George Foussias

George Foussias

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George Foussias

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Separable and Replicable Neural Strategies During Social Brain Function in People With and Without Severe Mental Illness.

Am J Psychiatry 2019 Jul 4;176(7):521-530. Epub 2019 Jan 4.

Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Toronto (Hawco, Calarco, Mulsant, Viviano, Dickie, Foussias, Voineskos); the Department of Psychiatry, University of Toronto, Toronto (Hawco, Foussias, Mulsant, Voineskos); Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Md. (Buchanan, Gold); Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, N.Y. (Argyelan, DeRosse, Malhotra); Zucker School of Medicine at Hofstra/Northwell, Hempstead, N.Y. (Argyelan, DeRosse, Malhotra); the Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at the University of California, Los Angeles (Iacoboni).

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http://dx.doi.org/10.1176/appi.ajp.2018.17091020DOI Listing
July 2019

Reward-driven decision-making impairments in schizophrenia.

Schizophr Res 2019 Apr 12;206:277-283. Epub 2018 Nov 12.

Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.schres.2018.11.004DOI Listing
April 2019

Goal-directed planning and action impairments in schizophrenia evaluated in a virtual environment.

Schizophr Res 2019 Apr 22;206:400-406. Epub 2018 Nov 22.

Schizophrenia Division and Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 250 College St., Toronto, Ontario M5T 1R8, Canada; Institute of Medical Science, Faculty of Medicine, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada; Department of Psychiatry, University of Toronto, 250 College St., Toronto, Ontario M5T 1R8, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S09209964183061
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http://dx.doi.org/10.1016/j.schres.2018.10.012DOI Listing
April 2019

Brain structure, cognition, and brain age in schizophrenia, bipolar disorder, and healthy controls.

Neuropsychopharmacology 2019 04 20;44(5):898-906. Epub 2018 Dec 20.

Kimel Family Translational Imaging-Genetics Laboratory, Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://www.nature.com/articles/s41386-018-0298-z
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http://dx.doi.org/10.1038/s41386-018-0298-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461913PMC
April 2019

Altered Transcranial Magnetic Stimulation-Electroencephalographic Markers of Inhibition and Excitation in the Dorsolateral Prefrontal Cortex in Major Depressive Disorder.

Biol Psychiatry 2019 03 18;85(6):477-486. Epub 2018 Oct 18.

Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2018.09.032DOI Listing
March 2019

Achievement motivation in early schizophrenia: Relationship with symptoms, cognition and functional outcome.

Early Interv Psychiatry 2018 12 23;12(6):1038-1044. Epub 2017 Feb 23.

Schizophrenia Division and Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada.

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http://doi.wiley.com/10.1111/eip.12405
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http://dx.doi.org/10.1111/eip.12405DOI Listing
December 2018

Resting-State Connectivity Biomarkers of Cognitive Performance and Social Function in Individuals With Schizophrenia Spectrum Disorder and Healthy Control Subjects.

Biol Psychiatry 2018 11 13;84(9):665-674. Epub 2018 Apr 13.

Kimel Family Translational Imaging-Genetics Research Lab, Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario; Department of Psychiatry, University of Toronto, Toronto, Ontario. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2018.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177285PMC
November 2018

Objective investigation of activity preference in schizophrenia: A pilot study.

Psychiatry Res 2018 09 16;267:551-559. Epub 2018 May 16.

Schizophrenia Division and Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 250 College St., Toronto, Ontario M5T 1R8, Canada.; Institute of Medical Science, Faculty of Medicine, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada.; Department of Psychiatry, University of Toronto, 250 College St., Toronto, Ontario M5T 1R8, Canada.

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http://dx.doi.org/10.1016/j.psychres.2018.05.039DOI Listing
September 2018

Anhedonia in depression and schizophrenia: A transdiagnostic challenge.

CNS Neurosci Ther 2018 07 23;24(7):615-623. Epub 2018 Apr 23.

Arthur Sommer Rotenberg Suicide and Depression Studies Program, St. Michael's Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1111/cns.12854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489811PMC
July 2018

Objective assessment of exploratory behaviour in schizophrenia using wireless motion capture.

Schizophr Res 2018 05 24;195:122-129. Epub 2017 Sep 24.

Schizophrenia Division and Campbell Family Research Institute, Centre for Addiction and Mental Health, 250 College St., Toronto, Ontario M5T 1R8, Canada; Institute of Medical Science, Faculty of Medicine, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada; Department of Psychiatry, University of Toronto, 250 College St., Toronto, Ontario M5T 1R8, Canada.

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http://dx.doi.org/10.1016/j.schres.2017.09.011DOI Listing
May 2018

Investigating the predictors of happiness, life satisfaction and success in schizophrenia.

Compr Psychiatry 2018 02 22;81:42-47. Epub 2017 Nov 22.

Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S0010440X173025
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http://dx.doi.org/10.1016/j.comppsych.2017.11.005DOI Listing
February 2018

Investigating consummatory and anticipatory pleasure across motivation deficits in schizophrenia and healthy controls.

Psychiatry Res 2017 08 23;254:112-117. Epub 2017 Apr 23.

Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S01651781163210
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http://dx.doi.org/10.1016/j.psychres.2017.04.040DOI Listing
August 2017

Switching to Clozapine Using Immediate Versus Gradual Antipsychotic Discontinuation: A Pilot, Double-Blind, Randomized Controlled Trial.

J Clin Psychiatry 2017 02;78(2):223-228

Schizophrenia Division, Centre for Addiction and Mental Health, 250 College St, Toronto, Ontario, M5T 1R8, Canada.

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http://dx.doi.org/10.4088/JCP.15m10286DOI Listing
February 2017

Using poverty of speech as a case study to explore the overlap between negative symptoms and cognitive dysfunction.

Schizophr Res 2016 10 27;176(2-3):411-416. Epub 2016 May 27.

Schizophrenia Division and Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.schres.2016.05.019DOI Listing
October 2016

Neurocognitive impairment in the deficit subtype of schizophrenia.

Eur Arch Psychiatry Clin Neurosci 2016 Aug 11;266(5):397-407. Epub 2015 Aug 11.

Schizophrenia Division and Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 250 College Street, Room 320, Toronto, ON, M5T 1R8, Canada.

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http://dx.doi.org/10.1007/s00406-015-0629-6DOI Listing
August 2016

Life satisfaction and happiness among young adults with schizophrenia.

Psychiatry Res 2016 Aug 1;242:174-179. Epub 2016 Jun 1.

Schizophrenia Division and Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.psychres.2016.05.046DOI Listing
August 2016

Motivational deficits in major depressive disorder: Cross-sectional and longitudinal relationships with functional impairment and subjective well-being.

Compr Psychiatry 2016 Apr 18;66:31-8. Epub 2015 Dec 18.

Schizophrenia Division and Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S0010440X153001
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http://dx.doi.org/10.1016/j.comppsych.2015.12.004DOI Listing
April 2016

Treating Negative Symptoms in Schizophrenia: an Update.

Curr Treat Options Psychiatry 2016;3:133-150. Epub 2016 Apr 8.

Department of Psychiatry, University of Toronto, Toronto, ON Canada ; Institute of Medical Science, University of Toronto, Toronto, ON Canada ; Centre for Addiction and Mental Health (CAMH), 250 College St., Toronto, ON M5T 1R8 Canada.

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http://dx.doi.org/10.1007/s40501-016-0075-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908169PMC
April 2016

Distress related to subclinical negative symptoms in a non-clinical sample: Role of dysfunctional attitudes.

Psychiatry Res 2015 Dec 5;230(2):249-54. Epub 2015 Sep 5.

Schizophrenia Division, Centre for Addiction and Mental Health, Toronto, ON, Canada; Institute of Medical Science, University of Toronto, Toronto, ON, Canada; Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.psychres.2015.09.002DOI Listing
December 2015

Measuring motivation in people with schizophrenia.

Schizophr Res 2015 Dec 29;169(1-3):423-426. Epub 2015 Sep 29.

Schizophrenia Division and Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.schres.2015.09.012DOI Listing
December 2015

Baseline social amotivation predicts 1-year functioning in UHR subjects: A validation and prospective investigation.

Eur Neuropsychopharmacol 2015 Dec 30;25(12):2187-96. Epub 2015 Oct 30.

Research Division, Institute of Mental Health, Singapore, Singapore; Department of General Psychiatry 1, Institute of Mental Health, Singapore, Singapore; Office of Clinical Sciences, Duke-NUS Graduate Medical School, Singapore, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2015.10.007DOI Listing
December 2015

Neuroimaging predictors of functional outcomes in schizophrenia at baseline and 6-month follow-up.

Schizophr Res 2015 Dec 24;169(1-3):69-75. Epub 2015 Oct 24.

Kimel Family Translational Imaging-Genetics Research Lab, Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, ON M5T 1R8, Canada; Institute of Medical Science, University of Toronto, 27 King's College Circle, Toronto, ON M5S, Canada; Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, 250 College Street, Toronto, ON M5T 1R8, Canada; Department of Psychiatry, University of Toronto, 27 King's College Circle, Toronto, ON, M5S, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2015.10.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681643PMC
December 2015

Values in First-Episode Schizophrenia.

Can J Psychiatry 2015 Nov;60(11):507-14

Professor, Department of Psychiatry, Complex Mental Illness Program, Schizophrenia Division, Centre for Addiction and Mental Health, Toronto, Ontario.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679131PMC
http://dx.doi.org/10.1177/070674371506001106DOI Listing
November 2015

Subtyping Schizophrenia by Treatment Response: Antipsychotic Development and the Central Role of Positive Symptoms.

Can J Psychiatry 2015 Nov;60(11):515-22

Lead, Subspecialty Clinics, Schizophrenia Division, Centre for Addiction and Mental Health, Toronto, Ontario; Professor, Department of Psychiatry, University of Toronto, Toronto, Ontario.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679132PMC
http://dx.doi.org/10.1177/070674371506001107DOI Listing
November 2015

Effort-based decision making as an objective paradigm for the assessment of motivational deficits in schizophrenia.

Schizophr Res 2015 Oct 26;168(1-2):483-90. Epub 2015 Jul 26.

Schizophrenia Division and Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.schres.2015.07.023DOI Listing
October 2015

The Effects of Video Games on Cognition and Brain Structure: Potential Implications for Neuropsychiatric Disorders.

Curr Psychiatry Rep 2015 Sep;17(9):71

Pharmacogenetics Research Clinic, Centre for Addiction and Mental Health, Toronto, ON, Canada.

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http://link.springer.com/10.1007/s11920-015-0609-6
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http://dx.doi.org/10.1007/s11920-015-0609-6DOI Listing
September 2015

Motivational deficits in early schizophrenia: prevalent, persistent, and key determinants of functional outcome.

Schizophr Res 2015 Aug 15;166(1-3):9-16. Epub 2015 May 15.

Schizophrenia Division, Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.schres.2015.04.040DOI Listing
August 2015

Examination of the validity of the Brief Neurocognitive Assessment (BNA) for schizophrenia.

Schizophr Res 2015 Aug 23;166(1-3):304-9. Epub 2015 May 23.

Schizophrenia Division, Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.schres.2015.05.015DOI Listing
August 2015

Determinants of patient-rated and clinician-rated illness severity in schizophrenia.

J Clin Psychiatry 2015 Jul;76(7):924-30

Schizophrenia Division, Centre for Addiction and Mental Health, 250 College St, Room 320, Toronto, Ontario, Canada M5T 1R8

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http://dx.doi.org/10.4088/JCP.14m09128DOI Listing
July 2015

Motivation and Social Cognition in Patients with Schizophrenia.

J Int Neuropsychol Soc 2015 Jul 2;21(6):436-43. Epub 2015 Jul 2.

1Schizophrenia Division and Campbell Family Mental Health Research Institute,Centre for Addiction and Mental Health,Toronto,Canada.

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http://dx.doi.org/10.1017/S1355617715000375DOI Listing
July 2015

Antipsychotics and amotivation.

Neuropsychopharmacology 2015 May 8;40(6):1539-48. Epub 2015 Jan 8.

1] Schizophrenia Division, Centre for Addiction and Mental Health, Toronto, Canada [2] Institute of Medical Science, University of Toronto, Toronto, Canada [3] Department of Psychiatry, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1038/npp.2015.3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397414PMC
May 2015

Further neuroimaging evidence for the deficit subtype of schizophrenia: a cortical connectomics analysis.

JAMA Psychiatry 2015 May;72(5):446-55

Kimel Family Translational Imaging Genetics Laboratory, Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada2Schizophrenia Division of the Complex Mental Illness Program, Centre for Addiction and Mental Health, Toronto.

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http://dx.doi.org/10.1001/jamapsychiatry.2014.3020DOI Listing
May 2015

Relationship between symptomatic improvement and overall illness severity in patients with schizophrenia.

J Clin Psychopharmacol 2015 Apr;35(2):128-33

From the *Schizophrenia Division, Centre for Addiction and Mental Health; and †Institute of Medical Science, and ‡Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/JCP.0000000000000286DOI Listing
April 2015

Clinical and functional outcomes in people with schizophrenia with a high sense of well-being.

J Nerv Ment Dis 2015 Mar;203(3):187-93

*Schizophrenia Division, Centre for Addiction and Mental Health; and †Institute of Medical Science and ‡Department of Psychiatry, University of Toronto, Toronto, Canada.

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http://pdfs.journals.lww.com/jonmd/2015/03000/Clinical_and_F
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/NMD.0000000000000266DOI Listing
March 2015

What does schizophrenia teach us about antipsychotics?

Can J Psychiatry 2015 Mar;60(3 Suppl 2):S14-8

Assistant Professor, Department of Psychiatry, University of Toronto, Toronto, Ontario; Staff Psychiatrist, Schizophrenia Program, Centre for Addiction and Mental Health, Toronto, Ontario; Scientist, Campbell Family Mental Health Research Institute, Toronto, Ontario.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418619PMC
March 2015

Extrapyramidal symptoms and cognitive test performance in patients with schizophrenia.

Schizophr Res 2015 Feb 1;161(2-3):351-6. Epub 2014 Dec 1.

Schizophrenia Division, Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.schres.2014.11.018DOI Listing
February 2015

Dissecting negative symptoms in schizophrenia: opportunities for translation into new treatments.

J Psychopharmacol 2015 Feb 16;29(2):116-26. Epub 2014 Dec 16.

Campbell Family Mental Health Research Institute, and Schizophrenia Division - Complex Mental Illness Program, Centre for Addiction and Mental Health, Toronto, ON, Canada Department of Psychiatry, University of Toronto, Toronto, ON, Canada Institute of Medical Science, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1177/0269881114562092DOI Listing
February 2015

Motivational deficits and cognitive test performance in schizophrenia.

JAMA Psychiatry 2014 Sep;71(9):1058-65

Schizophrenia Division, Centre for Addiction and Mental Health, Toronto, Ontario, Canada2Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada4Department of Psychiatry, University of Toronto, Toronto, Ontario.

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http://dx.doi.org/10.1001/jamapsychiatry.2014.1105DOI Listing
September 2014

Antipsychotic dosing: found in translation.

J Psychiatry Neurosci 2014 Jul;39(4):223-31

Institute of Medical Science, University of Toronto, Toronto, Ont.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074233PMC
July 2014

Effect of antipsychotic medication on overall life satisfaction among individuals with chronic schizophrenia: findings from the NIMH CATIE study.

Eur Neuropsychopharmacol 2014 Jul 15;24(7):1078-85. Epub 2014 Mar 15.

Schizophrenia Division, Centre for Addiction and Mental Health, Toronto, Ontario, Canada M5T 1R8; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.euroneuro.2014.03.001DOI Listing
July 2014

Daily activity patterns in remitted first-episode schizophrenia.

Compr Psychiatry 2014 Jul 13;55(5):1182-7. Epub 2014 Apr 13.

Schizophrenia Division, Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.comppsych.2014.04.001DOI Listing
July 2014

Negative symptoms of schizophrenia: clinical features, relevance to real world functioning and specificity versus other CNS disorders.

Eur Neuropsychopharmacol 2014 May 11;24(5):693-709. Epub 2013 Nov 11.

Centre for Addiction and Mental Health, University of Toronto, 250 College Street, Toronto, Ontario, Canada M5T 1R8; Department of Psychiatry, University of Toronto, 250 College Street, Toronto, Ontario, Canada M5T 1R8; Institute of Medical Science, Faculty of Medicine, University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario, Canada M5S 1A8.

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http://dx.doi.org/10.1016/j.euroneuro.2013.10.017DOI Listing
May 2014

Toward a more parsimonious assessment of neurocognition in schizophrenia: a 10-minute assessment tool.

J Psychiatr Res 2014 May 24;52:50-6. Epub 2014 Jan 24.

Schizophrenia Division, Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.jpsychires.2014.01.009DOI Listing
May 2014

Abbreviated quality of life scales for schizophrenia: comparison and utility of two brief community functioning measures.

Schizophr Res 2014 Apr 11;154(1-3):89-92. Epub 2014 Mar 11.

Schizophrenia Division, Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.schres.2014.02.013DOI Listing
April 2014

Schizophrenia, cognition, and psychosis.

JAMA Psychiatry 2014 Mar;71(3):336-7

Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1001/jamapsychiatry.2013.3532DOI Listing
March 2014

The neurobiology of relapse in schizophrenia.

Schizophr Res 2014 Feb 24;152(2-3):381-90. Epub 2013 Oct 24.

Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; Centre for Addiction and Mental Health (CAMH), Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.schres.2013.10.009DOI Listing
February 2014

Effect of intrinsic motivation on cognitive performance in schizophrenia: a pilot study.

Schizophr Res 2014 Jan 12;152(1):317-8. Epub 2013 Dec 12.

Schizophrenia Division, Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada.

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http://dx.doi.org/10.1016/j.schres.2013.11.037DOI Listing
January 2014

Amotivation and functional outcomes in early schizophrenia.

Psychiatry Res 2013 Dec 1;210(2):665-8. Epub 2013 Aug 1.

Schizophrenia Division, Centre for Addiction and Mental Health, Toronto, ON, Canada; Institute of Medical Science, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2013.07.024DOI Listing
December 2013

Neural substrates underlying effort computation in schizophrenia.

Neurosci Biobehav Rev 2013 Dec 12;37(10 Pt 2):2649-65. Epub 2013 Sep 12.

Schizophrenia Division, Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neubiorev.2013.09.001DOI Listing
December 2013

Clinical determinants of life satisfaction in chronic schizophrenia: data from the CATIE study.

Schizophr Res 2013 Dec 1;151(1-3):203-8. Epub 2013 Nov 1.

Schizophrenia Division, Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2013.10.021DOI Listing
December 2013

Simulating real world functioning in schizophrenia using a naturalistic city environment and single-trial, goal-directed navigation.

Front Behav Neurosci 2013 26;7:180. Epub 2013 Nov 26.

Institute of Medical Science, University of Toronto ON, Canada ; Centre for Addiction and Mental Health, Campbell Family Mental Health Research Institute Toronto, ON, Canada.

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http://dx.doi.org/10.3389/fnbeh.2013.00180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840323PMC
December 2013

Incentive motivation deficits in schizophrenia reflect effort computation impairments during cost-benefit decision-making.

J Psychiatr Res 2013 Nov 28;47(11):1590-6. Epub 2013 Aug 28.

Schizophrenia Division, Centre for Addiction and Mental Health, 250 College Street, Toronto, ON, Canada M5T 1R8; Institute of Medical Science, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2013.08.003DOI Listing
November 2013

Impairments in both reward and punishment guided reinforcement learning in schizophrenia.

Schizophr Res 2013 Nov 6;150(2-3):592-3. Epub 2013 Sep 6.

Schizophrenia Division, Centre for Addiction and Mental Health, Toronto, ON, Canada; Institute of Medical Science, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2013.08.012DOI Listing
November 2013

Using treatment response to subtype schizophrenia: proposal for a new paradigm in classification.

Schizophr Bull 2013 Nov 17;39(6):1169-72. Epub 2013 Sep 17.

*To whom correspondence should be addressed; Complex Mental Illness Division-Schizophrenia Program, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada M5T 1R8; tel: 416-535-8501, fax: 416-979-4292, e-mail:

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http://dx.doi.org/10.1093/schbul/sbt137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796094PMC
November 2013

Antipsychotic response in first-episode schizophrenia: efficacy of high doses and switching.

Eur Neuropsychopharmacol 2013 Sep 22;23(9):1017-22. Epub 2013 May 22.

Centre for Addiction and Mental Health, Ontario, Canada; Department of Psychiatry, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.euroneuro.2013.04.010DOI Listing
September 2013

Neuroimaging evidence for the deficit subtype of schizophrenia.

JAMA Psychiatry 2013 May;70(5):472-80

Department of Psychiatry, Centre for Addiction and Mental Health, Toronto, Canada.

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http://dx.doi.org/10.1001/jamapsychiatry.2013.786DOI Listing
May 2013

Clozapine and therapeutic drug monitoring: is there sufficient evidence for an upper threshold?

Psychopharmacology (Berl) 2013 Feb 22;225(3):505-18. Epub 2012 Nov 22.

Schizophrenia Program, Centre for Addiction and Mental Health, ), Toronto, Ontario, Canada,

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http://dx.doi.org/10.1007/s00213-012-2922-7DOI Listing
February 2013

Clozapine's role in the treatment of first-episode schizophrenia.

Am J Psychiatry 2013 Feb;170(2):146-51

Department of Psychiatry, University of Toronto, Canada.

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http://dx.doi.org/10.1176/appi.ajp.2012.12060778DOI Listing
February 2013

Happiness in first-episode schizophrenia.

Schizophr Res 2012 Oct 15;141(1):98-103. Epub 2012 Aug 15.

Department of Psychiatry, Faculty of Medicine, University of Toronto, Canada.

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http://dx.doi.org/10.1016/j.schres.2012.07.012DOI Listing
October 2012

An algorithm-based approach to first-episode schizophrenia: response rates over 3 prospective antipsychotic trials with a retrospective data analysis.

J Clin Psychiatry 2011 Nov 8;72(11):1439-44. Epub 2011 Mar 8.

Schizophrenia Program, Centre for Addiction and Mental Health, 250 College St, Toronto, Ontario, M5T 1R8, Canada.

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http://dx.doi.org/10.4088/JCP.09m05785yelDOI Listing
November 2011

Schizophrenia as a disorder of too little dopamine: implications for symptoms and treatment.

Expert Rev Neurother 2011 Apr;11(4):589-607

University of Toronto, Toronto, Ontario, Canada.

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http://www.tandfonline.com/doi/full/10.1586/ern.10.191
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http://dx.doi.org/10.1586/ern.10.191DOI Listing
April 2011

Long-acting injectable antipsychotics in the treatment of schizophrenia: their role in relapse prevention.

Expert Opin Pharmacother 2010 Oct;11(14):2301-17

Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1517/14656566.2010.499125DOI Listing
October 2010

Where to position clozapine: re-examining the evidence.

Can J Psychiatry 2010 Oct;55(10):677-84

Schizophrenia Program, Centre for Addiction and Mental Health, Toronto, Ontario.

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http://dx.doi.org/10.1177/070674371005501007DOI Listing
October 2010

Negative symptoms in schizophrenia: avolition and Occam's razor.

Schizophr Bull 2010 Mar 21;36(2):359-69. Epub 2008 Jul 21.

Department of Psychiatry, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1093/schbul/sbn094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2833114PMC
March 2010

Antipsychotics and schizophrenia: from efficacy and effectiveness to clinical decision-making.

Can J Psychiatry 2010 Mar;55(3):117-25

Schizophrenia Program, Centre for Addiction and Mental Health, Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, Ontario.

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http://dx.doi.org/10.1177/070674371005500302DOI Listing
March 2010

Progress in defining optimal treatment outcome in schizophrenia.

CNS Drugs 2010 Jan;24(1):9-20

Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

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http://link.springer.com/10.2165/11530250-000000000-00000
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http://dx.doi.org/10.2165/11530250-000000000-00000DOI Listing
January 2010

Genomic organization of the siglec gene locus on chromosome 19q13.4 and cloning of two new siglec pseudogenes.

Gene 2002 Mar;286(2):259-70

Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, 600 University Avenue, Toronto, ON, Canada M5G 1X5.

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http://dx.doi.org/10.1016/s0378-1119(02)00432-8DOI Listing
March 2002