George Cotsarelis

George Cotsarelis

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George Cotsarelis

George Cotsarelis

Publications by authors named "George Cotsarelis"

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A cross-sectional survey and analysis of Dermatology Foundation Career Development Award recipients.

J Am Acad Dermatol 2019 Nov 28;81(5):1093-1098. Epub 2018 Nov 28.

Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01909622183296
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http://dx.doi.org/10.1016/j.jaad.2018.11.034DOI Listing
November 2019

Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing.

Nat Commun 2018 11 21;9(1):4903. Epub 2018 Nov 21.

The Ronald O. Perelman Department of Dermatology and Department of Cell Biology, New York University School of Medicine, New York, NY, 10016, USA.

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http://dx.doi.org/10.1038/s41467-018-07142-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249328PMC
November 2018

Isolation of Mouse Hair Follicle Bulge Stem Cells and Their Functional Analysis in a Reconstitution Assay.

Methods Mol Biol 2016 ;1453:57-69

Department of Dermatology, University of Pennsylvania Medical Center, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/978-1-4939-3786-8_8DOI Listing
January 2018

Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival.

Sci Transl Med 2016 Feb 3;8(324):324ra16. Epub 2016 Feb 3.

The Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/scitranslmed.aad3305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870001PMC
February 2016

TR3 is preferentially expressed by bulge epithelial stem cells in human hair follicles.

Lab Invest 2016 Jan 2;96(1):81-8. Epub 2015 Nov 2.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/labinvest.2015.125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915568PMC
January 2016

Generation of folliculogenic human epithelial stem cells from induced pluripotent stem cells.

Nat Commun 2014 ;5:3071

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/ncomms4071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049184PMC
November 2015

Vismodegib resistance in basal cell carcinoma: not a smooth fit.

Cancer Cell 2015 Mar;27(3):315-6

Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, BRB 1053, 421 Curie Boulevard, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.02.009DOI Listing
March 2015

Hypoxia-inducible factors regulate filaggrin expression and epidermal barrier function.

J Invest Dermatol 2015 Feb 7;135(2):454-461. Epub 2014 Jul 7.

Abramson Family Cancer Research Institute, Philadelphia, Pennsylvania, USA; Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Howard Hughes Medical Institute, Philadelphia, Pennsylvania, USA. Electronic address:

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http://dx.doi.org/10.1038/jid.2014.283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286527PMC
February 2015

CD133 expression correlates with membrane beta-catenin and E-cadherin loss from human hair follicle placodes during morphogenesis.

J Invest Dermatol 2015 Jan 10;135(1):45-55. Epub 2014 Jul 10.

Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address:

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http://dx.doi.org/10.1038/jid.2014.292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465595PMC
January 2015

Direct conversion of mouse and human fibroblasts to functional melanocytes by defined factors.

Nat Commun 2014 Dec 16;5:5807. Epub 2014 Dec 16.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/ncomms6807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335710PMC
December 2014

Dissociated human dermal papilla cells induce hair follicle neogenesis in grafted dermal-epidermal composites.

J Invest Dermatol 2014 Feb 7;134(2):538-540. Epub 2013 Aug 7.

Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA. Electronic address:

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http://dx.doi.org/10.1038/jid.2013.337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947143PMC
February 2014

Retinoids putting the "a" in alopecia.

J Invest Dermatol 2013 Feb;133(2):285-6

Department of Dermatology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/jid.2012.441DOI Listing
February 2013

Epithelial stem cells and implications for wound repair.

Semin Cell Dev Biol 2012 Dec 17;23(9):946-53. Epub 2012 Oct 17.

Department of Dermatology, Kligman Laboratories, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.semcdb.2012.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518754PMC
December 2012

Characterization and quantification of wound-induced hair follicle neogenesis using in vivo confocal scanning laser microscopy.

Skin Res Technol 2011 Nov 15;17(4):387-97. Epub 2011 Apr 15.

School of Biomedical Engineering, Science & Health Systems, Drexel University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/j.1600-0846.2011.00508.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164919PMC
November 2011

Fox-Fordyce disease following axillary laser hair removal.

Arch Dermatol 2011 May;147(5):573-6

Department of Dermatology, Hospital of the University of Pennsylvania, 3600 Spruce St, 2 Maloney Building, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1001/archdermatol.2011.103DOI Listing
May 2011

Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells.

J Clin Invest 2011 Feb 4;121(2):613-22. Epub 2011 Jan 4.

Department of Dermatology, Kligman Laboratories, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://www.jci.org/articles/view/44478
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http://dx.doi.org/10.1172/JCI44478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026732PMC
February 2011

Keratin 15-positive stem cells give rise to basal cell carcinomas in irradiated Ptch1(+/-) mice.

Cancer Cell 2011 Jan;19(1):5-6

Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, PA, 19104, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15356108110000
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http://dx.doi.org/10.1016/j.ccr.2011.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038118PMC
January 2011

Neural Wiskott-Aldrich syndrome protein modulates Wnt signaling and is required for hair follicle cycling in mice.

J Clin Invest 2010 Feb 11;120(2):446-56. Epub 2010 Jan 11.

Gastrointestinal Unit and Center for Inflammatory Bowel Disease, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1172/JCI36478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810069PMC
February 2010

Review of hair follicle dermal cells.

J Dermatol Sci 2010 Jan;57(1):2-11

Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.jdermsci.2009.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818774PMC
January 2010

Targeted disruption of stat3 reveals a major role for follicular stem cells in skin tumor initiation.

Cancer Res 2009 Oct 8;69(19):7587-94. Epub 2009 Sep 8.

Department of Carcinogenesis, The University of Texas M.D. Anderson Cancer Center, Science Park-Research Division, Smithville, TX 78957, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-1180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043290PMC
October 2009

Epidermal cells rev up reprogramming.

Nat Biotechnol 2008 Nov;26(11):1243-4

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http://dx.doi.org/10.1038/nbt1108-1243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147182PMC
November 2008

Is the hair follicle necessary for normal wound healing?

J Invest Dermatol 2008 May;128(5):1059-61

Department of Dermatology, Kligman Laboratories, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/jid.2008.86DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147170PMC
May 2008

The longest telomeres: a general signature of adult stem cell compartments.

Genes Dev 2008 Mar 18;22(5):654-67. Epub 2008 Feb 18.

Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Centre, Madrid E-28029, Spain.

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http://dx.doi.org/10.1101/gad.451008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259034PMC
March 2008

Defining hair follicles in the age of stem cell bioengineering.

J Invest Dermatol 2007 Sep;127(9):2098-100

Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

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http://dx.doi.org/10.1038/sj.jid.5700947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388139PMC
September 2007

How hair gets its pigment.

Cell 2007 Sep;130(5):779-81

Department of Genetics, Stanford School of Medicine, Stanford, CA 94305, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S009286740701095
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http://dx.doi.org/10.1016/j.cell.2007.08.032DOI Listing
September 2007

Turning skin into embryonic stem cells.

Nat Med 2007 Jul;13(7):783-4

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http://dx.doi.org/10.1038/nm0707-783DOI Listing
July 2007

Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss.

Cell Stem Cell 2007 Jun;1(1):113-26

Abramson Family Cancer Research Institute, Department of Cancer Biology, University of Pennsylvania School of Medicine, 421 Curie Boulevard, Philadelphia, PA 19104-6160, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S193459090700005
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http://dx.doi.org/10.1016/j.stem.2007.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920603PMC
June 2007

Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding.

Nature 2007 May;447(7142):316-20

Department of Dermatology, Kligman Laboratories, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://www.nature.com/articles/nature05766
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http://dx.doi.org/10.1038/nature05766DOI Listing
May 2007

Epithelial stem cells: a folliculocentric view.

J Invest Dermatol 2006 Jul;126(7):1459-68

Department of Dermatology, Kligman Laboratories, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/sj.jid.5700376DOI Listing
July 2006

Report from the cicatricial alopecia colloquium.

J Invest Dermatol 2006 Mar;126(3):539-41

Aderans Research Institute, Philadelphia, Pennsylvania 19104-3318, USA.

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http://dx.doi.org/10.1038/sj.jid.5700148DOI Listing
March 2006

Gene expression profiling gets to the root of human hair follicle stem cells.

J Clin Invest 2006 Jan;116(1):19-22

University of Pennsylvania School of Medicine, M8 Stellar-Chance Laboratories, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1172/JCI27490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1323274PMC
January 2006

Gene expression profiling gets to the root of human hair follicle stem cells.

J Clin Invest 2006 Jan;116(1):19-22

University of Pennsylvania School of Medicine, M8 Stellar-Chance Laboratories, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1172/JCI27490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1323274PMC
January 2006

Bioengineering the hair follicle: fringe benefits of stem cell technology.

Curr Opin Biotechnol 2005 Oct;16(5):493-7

Aderans Research Institute, 3401 Market Street, Philadelphia, Pennsylvania 19104, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S095816690500129
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http://dx.doi.org/10.1016/j.copbio.2005.08.002DOI Listing
October 2005

Developmental biology. Rac1 up for epidermal stem cells.

Science 2005 Aug;309(5736):890-1

Institute of Biochemistry, University of Lausanne, Chemin de Bovaresses 155, CH-1066 Epalinges, Switzerland.

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http://dx.doi.org/10.1126/science.1117192DOI Listing
August 2005

Hair follicle stem cells in the lower bulge form the secondary germ, a biochemically distinct but functionally equivalent progenitor cell population, at the termination of catagen.

Differentiation 2004 Dec;72(9-10):548-57

Department of Dermatology, University of Pennsylvania School of Medicine, M8 Stellar-Chance Laboratories, 422 Curie Blvd, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1111/j.1432-0436.2004.07209008.xDOI Listing
December 2004

Desmogleins 1 and 3 in the companion layer anchor mouse anagen hair to the follicle.

J Invest Dermatol 2004 Nov;123(5):817-22

Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0022202X1532036
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http://dx.doi.org/10.1111/j.0022-202X.2004.23479.xDOI Listing
November 2004

Capturing and profiling adult hair follicle stem cells.

Nat Biotechnol 2004 Apr 14;22(4):411-7. Epub 2004 Mar 14.

Department of Dermatology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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http://dx.doi.org/10.1038/nbt950DOI Listing
April 2004

Keratin 15 promoter targets putative epithelial stem cells in the hair follicle bulge.

J Invest Dermatol 2003 Nov;121(5):963-8

Department of Dermatology, Kligman Laboratories, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0022202X1530530
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http://dx.doi.org/10.1046/j.1523-1747.2003.12600.xDOI Listing
November 2003

Decreased serum ferritin is associated with alopecia in women.

J Invest Dermatol 2003 Nov;121(5):985-8

Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1046/j.1523-1747.2003.12540.xDOI Listing
November 2003

Scarring alopecia associated with mastocytosis.

J Cutan Pathol 2003 Oct;30(9):561-5

Departments of Pathology and Laboratory Medicine, Hospital of University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1034/j.1600-0560.2003.00093.xDOI Listing
October 2003

Differential expression of cyclin D1 in the human hair follicle.

Am J Pathol 2003 Sep;163(3):969-78

Department of Pathology, Hospital of University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868252PMC
http://dx.doi.org/10.1016/S0002-9440(10)63456-6DOI Listing
September 2003

Multiply recurrent trichilemmal carcinoma with perineural invasion and cytokeratin 17 positivity.

Dermatol Surg 2003 Aug;29(8):886-9

Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://pdfs.journals.lww.com/dermatologicsurgery/2003/08000/
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http://dx.doi.org/10.1046/j.1524-4725.2003.29241.xDOI Listing
August 2003

Desmoglein isotype expression in the hair follicle and its cysts correlates with type of keratinization and degree of differentiation.

J Invest Dermatol 2003 Jun;120(6):1052-7

Department of Pathology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1046/j.1523-1747.2003.12234.xDOI Listing
June 2003

Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34.

J Invest Dermatol 2003 Apr;120(4):501-11

Cancer Biology Group, National Center for Toxicogenomics, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0022202X1530224
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http://dx.doi.org/10.1046/j.1523-1747.2003.12088.xDOI Listing
April 2003

Acrodermatitis enteropathica associated with anorexia nervosa.

JAMA 2002 Dec;288(21):2655-6

Department of Dermatology, Brown University, Providence, RI, USA.

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http://dx.doi.org/10.1001/jama.288.21.2655DOI Listing
December 2002