George A Mashour

George A Mashour

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George A Mashour

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Independent discussion sections for improving inferential reproducibility in published research.

Br J Anaesth 2019 04 22;122(4):413-420. Epub 2019 Jan 22.

Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1016/j.bja.2018.12.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435840PMC
April 2019

General Anesthesia and the Cortex: Communication Breakdown?

Authors:
George A Mashour

Anesthesiology 2019 Apr;130(4):526-527

From the Center for Consciousness Science, Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000002636DOI Listing
April 2019

Escape From Oblivion: Neural Mechanisms of Emergence From General Anesthesia.

Anesth Analg 2019 Apr;128(4):726-736

Department of Anesthesiology, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1213/ANE.0000000000004006DOI Listing
April 2019

Cortical dynamics during psychedelic and anesthetized states induced by ketamine.

Neuroimage 2019 Apr 5;196:32-40. Epub 2019 Apr 5.

Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, United States; Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, United States; Neuroscience Graduate Program, University of Michigan Medical School, Ann Arbor, United States.

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http://dx.doi.org/10.1016/j.neuroimage.2019.03.076DOI Listing
April 2019

Relationship of critical dynamics, functional connectivity, and states of consciousness in large-scale human brain networks.

Neuroimage 2019 Mar 6;188:228-238. Epub 2018 Dec 6.

Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, United States; Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI, United States. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2018.12.011DOI Listing
March 2019

Dynamic Cortical Connectivity during General Anesthesia in Healthy Volunteers.

Anesthesiology 2019 03 28. Epub 2019 Mar 28.

From the Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan (D.L., P.E.V., G.A.M.) the Department of Anesthesiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania (M.B.K.) the Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri (M.S.A.). From the Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan From the Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan From the Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan From the Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan From the Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan From the Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan From the Department of Anesthesiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia From the Department of Anesthesiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia From the Department of Anesthesiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia From the Department of Anesthesiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia From the Department of Anesthesiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia From the Department of Anesthesiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia From the Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri From the Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri From the Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri.

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http://dx.doi.org/10.1097/ALN.0000000000002656DOI Listing
March 2019

Dynamic Cortical Connectivity during General Anesthesia in Surgical Patients.

Anesthesiology 2019 Mar 28. Epub 2019 Mar 28.

From the Department of Anesthesiology (P.E.V., D.L., M.Z., A.P.L., K.I.I., A.M.M., G.A.M.) the Center for Consciousness Science (P.E.V., D.L., G.A.M.) the Neuroscience Graduate Program (G.A.M.), University of Michigan Medical School Ann Arbor, Michigan the Department of Psychology, University of Michigan, Ann Arbor, Michigan (K.I.I.).

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http://dx.doi.org/10.1097/ALN.0000000000002677DOI Listing
March 2019

Role of Network Science in the Study of Anesthetic State Transitions.

Anesthesiology 2018 Nov;129(5):1029-1044

From the Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000002228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191341PMC
November 2018

Highways of the Brain, Traffic of the Mind.

Authors:
George A Mashour

Anesthesiology 2018 Nov;129(5):869-871

From the Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000002385DOI Listing
November 2018

Increasing Role of Maternal Immune Activation in Neurodevelopmental Disorders.

Front Behav Neurosci 2018 5;12:230. Epub 2018 Oct 5.

Center for Consciousness Science, Department of Anesthesiology, University of Michigan, Ann Arbor, MI, United States.

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https://www.frontiersin.org/article/10.3389/fnbeh.2018.00230
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http://dx.doi.org/10.3389/fnbeh.2018.00230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182081PMC
October 2018

Consciousness and Personhood in Medical Care.

Front Hum Neurosci 2018 2;12:306. Epub 2018 Aug 2.

Department of Anesthesiology, Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI, United States.

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http://dx.doi.org/10.3389/fnhum.2018.00306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082939PMC
August 2018

Mechanisms of hysteresis in human brain networks during transitions of consciousness and unconsciousness: Theoretical principles and empirical evidence.

PLoS Comput Biol 2018 08 30;14(8):e1006424. Epub 2018 Aug 30.

Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1006424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135517PMC
August 2018

Differentiating Drug-related and State-related Effects of Dexmedetomidine and Propofol on the Electroencephalogram.

Anesthesiology 2018 07;129(1):22-36

From the Turku PET Centre, University of Turku and the Hospital District of Southwest Finland, Turku, Finland (A.S., K.K., J.L., A.M., H.S.) the Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, Turku, Finland (A.S., R.E.K., M.K., A.M., H.S.) the Department of Psychology and Speech-Language Pathology, and Turku Brain and Mind Center (R.E.K., K.V., A.R.) the Department of Pharmacology, Drug Development and Therapeutics (H.S.) University of Turku, Turku, Finland; the Department of Anesthesiology, Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, Michigan (D.L., G.A.M.) the Department of Anesthesiology and Intensive Care, Oulu University Hospital, Oulu, Finland (K.K.) the Department of Intensive Care, Tampere University Hospital, Tampere, Finland (J.L.) the Department of Clinical Medicine, Biostatistics, University of Turku and Turku University Hospital, Turku, Finland (T.V.) the Department of Cognitive Neuroscience and Philosophy, School of Bioscience, University of Skövde, Skövde, Sweden (K.V., A.R.).

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http://dx.doi.org/10.1097/ALN.0000000000002192DOI Listing
July 2018

Differential Role of Prefrontal and Parietal Cortices in Controlling Level of Consciousness.

Curr Biol 2018 Jul 21;28(13):2145-2152.e5. Epub 2018 Jun 21.

Department of Anesthesiology, University of Michigan, 7433 Medical Science Building 1, 1150 West Medical Center Drive, Ann Arbor, MI 48109-5615, USA; Center for Consciousness Science, University of Michigan, Ann Arbor, MI 48109, USA; Neuroscience Graduate Program, University of Michigan, 4137 Undergraduate Science Building, 204 Washtenaw Avenue, Ann Arbor, MI 48109-2215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2018.05.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039257PMC
July 2018

Right now, in the right way: U. S. Food and Drug Administration's expanded access program and patient rights.

J Clin Transl Sci 2018 Jun;2(3):115-117

Michigan Institute for Clinical and Health Research (MICHR), Office of Research, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1017/cts.2018.318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202008PMC
June 2018

Neurologic Considerations and Complications Related to Liver Transplantation.

Anesthesiology 2018 05;128(5):1008-1014

From the Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000002148DOI Listing
May 2018

The controversial correlates of consciousness.

Authors:
George A Mashour

Science 2018 05;360(6388):493-494

Center for Consciousness Science, Department of Anesthesiology, Neuroscience Graduate Program, University of Michigan Medical School, University Hospital, 1H247, 1500 East Medical Center Drive, SPC-5048, Ann Arbor, MI 48109-5048, USA.

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http://dx.doi.org/10.1126/science.aat5616DOI Listing
May 2018

Neural Correlates of Unconsciousness in Large-Scale Brain Networks.

Trends Neurosci 2018 03 3;41(3):150-160. Epub 2018 Feb 3.

Neuroscience Graduate Program, Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1016/j.tins.2018.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835202PMC
March 2018

Systems Neuroscience: The Exciting Journey to Oblivion.

Curr Biol 2018 Mar;28(5):R223-R224

Center for Consciousness Science, University of Michigan, Ann Arbor, MI 48109, USA; Department of Anesthesiology and Critical Care, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.cub.2018.01.074DOI Listing
March 2018

Bottom-Up and Top-Down Mechanisms of General Anesthetics Modulate Different Dimensions of Consciousness.

Front Neural Circuits 2017 20;11:44. Epub 2017 Jun 20.

Department of Anesthesiology, University of MichiganAnn Arbor, MI, United States.

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http://dx.doi.org/10.3389/fncir.2017.00044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476707PMC
February 2018

Timescales of Intrinsic BOLD Signal Dynamics and Functional Connectivity in Pharmacologic and Neuropathologic States of Unconsciousness.

J Neurosci 2018 Feb 31;38(9):2304-2317. Epub 2018 Jan 31.

Department of Anesthesiology and Center for Consciousness Science, University of Michigan, Ann Arbor, Michigan 48109 and

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http://dx.doi.org/10.1523/JNEUROSCI.2545-17.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830518PMC
February 2018

Estimating the Integrated Information Measure Phi from High-Density Electroencephalography during States of Consciousness in Humans.

Front Hum Neurosci 2018 16;12:42. Epub 2018 Feb 16.

Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, United States.

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http://dx.doi.org/10.3389/fnhum.2018.00042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821001PMC
February 2018

Functional Brain Network Mechanism of Hypersensitivity in Chronic Pain.

Sci Rep 2018 01 10;8(1):243. Epub 2018 Jan 10.

Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, 48109, USA.

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http://dx.doi.org/10.1038/s41598-017-18657-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762762PMC
January 2018

Comment on the PODCAST study - Authors' reply.

Lancet 2017 11;390(10110):2346

Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1016/S0140-6736(17)32896-9DOI Listing
November 2017

Adapting the model of consumer behavior to the design of an online health research recruitment tool.

J Clin Transl Sci 2017 Aug 14;1(4):240-245. Epub 2017 Aug 14.

Michigan Institute for Clinical and Health Research, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1017/cts.2017.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890321PMC
August 2017

Toward a science of translational science.

J Clin Transl Sci 2017 Aug 14;1(4):253-255. Epub 2017 Aug 14.

Office of Research, Medical School, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1017/cts.2017.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890312PMC
August 2017

Neurophysiologic Correlates of Ketamine Sedation and Anesthesia: A High-density Electroencephalography Study in Healthy Volunteers.

Anesthesiology 2017 07;127(1):58-69

From the Department of Anesthesiology (P.E.V., T.B.-B., U.L., D.L., H.K., E.J., V.T., A.M.M., B.S.K., P.P., G.A.M.), Center for Consciousness Science (P.E.V., T.B.-B., U.L., D.L., H.K., G.A.M.), and Neuroscience Graduate Program (G.A.M.), University of Michigan Medical School, Ann Arbor, Michigan; and the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois (A.B.P.).

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http://dx.doi.org/10.1097/ALN.0000000000001671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478453PMC
July 2017

Protocol for the Reconstructing Consciousness and Cognition (ReCCognition) Study.

Front Hum Neurosci 2017 7;11:284. Epub 2017 Jun 7.

Department of Anesthesiology and Critical Care, Perelman School of Medicine, University of PennsylvaniaPhiladelphia, PA, United States.

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http://dx.doi.org/10.3389/fnhum.2017.00284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461274PMC
June 2017

Relationship of Topology, Multiscale Phase Synchronization, and State Transitions in Human Brain Networks.

Front Comput Neurosci 2017 30;11:55. Epub 2017 Jun 30.

Center for Consciousness Science, University of Michigan Medical SchoolAnn Arbor, MI, United States.

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http://dx.doi.org/10.3389/fncom.2017.00055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492767PMC
June 2017

Effect of a Clinical and Translational Science Award institute on grant funding in a major research university.

J Clin Transl Sci 2017 Apr 2;1(2):88-93. Epub 2017 Mar 2.

Office of Research, Medical School, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1017/cts.2016.32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444804PMC
April 2017

Network Inefficiency: A Rosetta Stone for the Mechanism of Anesthetic-induced Unconsciousness.

Authors:
George A Mashour

Anesthesiology 2017 03;126(3):366-368

From the Department of Anesthesiology, Center for Consciousness Science, Neuroscience Graduate Program, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000001510DOI Listing
March 2017

Paradoxical Emergence: Administration of Subanesthetic Ketamine during Isoflurane Anesthesia Induces Burst Suppression but Accelerates Recovery.

Anesthesiology 2017 Mar;126(3):482-494

From the Department of Anesthesiology (V.S.H.-W., D.L., G.A.M.), Center of Consciousness Science (V.S.H.-W., D.L., G.A.M.), and Neuroscience Graduate Program (G.A.M.), University of Michigan, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000001512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309196PMC
March 2017

Accelerated Recovery of Consciousness after General Anesthesia Is Associated with Increased Functional Brain Connectivity in the High-Gamma Bandwidth.

Front Syst Neurosci 2017 24;11:16. Epub 2017 Mar 24.

Department of Anesthesiology, University of MichiganAnn Arbor, MI, USA; Center for Consciousness Science, University of MichiganAnn Arbor, MI, USA; Neuroscience Graduate Program, University of MichiganAnn Arbor, MI, USA.

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http://dx.doi.org/10.3389/fnsys.2017.00016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364164PMC
March 2017

Incidence of Connected Consciousness after Tracheal Intubation: A Prospective, International, Multicenter Cohort Study of the Isolated Forearm Technique.

Anesthesiology 2017 02;126(2):214-222

From the Department of Anesthesiology, University of Wisconsin-Madison, Madison, Wisconsin (R.D.S., A.R., C.B., A.H., R.M.B.); Department of Anesthesia, Rambam Healthcare Campus, Haifa, Israel (A.R.); Department of Anesthesiology and Critical Care, Houston Methodist Hospital, Houston, Texas (R.M.B.); Department of Anaesthesia, Waikato Clinical School, University of Auckland, Hamilton, New Zealand (A.G., J.W., J.S.); Department of Anesthesiology; University Hospital RWTH Aachen, Aachen, Germany (A.S., R.R., M.C.); Department of Anesthesia and Intensive Care Medicine, CHU University Hospital of Liège, Liège, Belgium (A.D., G.T., V.B.); University Department of Anesthesia and Intensive Care Medicine, CHR Citadelle and CHU University Hospital of Liège, Liège, Belgium (A.D., G.T., V.B.); Department of Anesthesiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands, (S.T., S.M., A.A.); and Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan (P.E.V., H.F., G.A.M.).

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http://dx.doi.org/10.1097/ALN.0000000000001479DOI Listing
February 2017

Repertoire of mesoscopic cortical activity is not reduced during anesthesia.

Neuroscience 2016 Dec 14;339:402-417. Epub 2016 Oct 14.

Department of Anesthesiology, Center for Consciousness Science, Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI, United States.

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http://dx.doi.org/10.1016/j.neuroscience.2016.10.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118138PMC
December 2016

Network-level Mechanisms of Ketamine Anesthesia.

Authors:
George A Mashour

Anesthesiology 2016 11;125(5):830-831

From the Department of Anesthesiology, Center for Consciousness Science, Neuroscience Graduate Program, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000001276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5183540PMC
November 2016

Neural Correlates of Wakefulness, Sleep, and General Anesthesia: An Experimental Study in Rat.

Anesthesiology 2016 11;125(5):929-942

From the Department of Anesthesiology (D.P., H.L., G.A.M.), Center for Consciousness Science (D.P., B.H.S., G.A.M.), and Neuroscience Graduate Program (G.A.M.), University of Michigan, Ann Arbor, Michigan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069172PMC
http://dx.doi.org/10.1097/ALN.0000000000001342DOI Listing
November 2016

Neural Correlates of Sevoflurane-induced Unconsciousness Identified by Simultaneous Functional Magnetic Resonance Imaging and Electroencephalography.

Anesthesiology 2016 11;125(5):861-872

From the Departments of Neurology (D.G., G.R., A.T., M.M., R.I.), Anesthesiology (A.R., T.K., P.K., J.P., S.B., A.T., M.M., E.F.K., D.J.), and Neuroradiology (V.R., C.P., C.Z.), Klinikum rechts der Isar der Technischen Universität München, München, Germany; and Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan (G.A.M.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069173PMC
http://dx.doi.org/10.1097/ALN.0000000000001322DOI Listing
November 2016

Disconnecting Consciousness: Is There a Common Anesthetic End Point?

Anesth Analg 2016 11;123(5):1228-1240

From the Department of Anesthesiology, Center for Consciousness Science, University of Michigan, Ann Arbor, Michigan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073005PMC
http://dx.doi.org/10.1213/ANE.0000000000001353DOI Listing
November 2016

Recognition and Management of Perioperative Stroke in Hospitalized Patients.

A A Case Rep 2016 Aug;7(3):55-6

From the *Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan; †University of Michigan Medical School, Ann Arbor, Michigan; and ‡Department of Anesthesia, University of California San Francisco School of Medicine, San Francisco, California.

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http://dx.doi.org/10.1213/XAA.0000000000000342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975429PMC
August 2016

The Neurobiology of Anesthetic Emergence.

J Neurosurg Anesthesiol 2016 Jul;28(3):250-5

Department of Anesthesiology, Division of Neuroanesthesiology, Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI.

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http://pdfs.journals.lww.com/jnsa/9000/00000/The_Neurobiolog
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http://pdfs.journals.lww.com/jnsa/2016/07000/The_Neurobiolog
Web Search
http://dx.doi.org/10.1097/ANA.0000000000000212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752918PMC
July 2016

Disruption of corticocortical information transfer during ketamine anesthesia in the primate brain.

Neuroimage 2016 07 16;134:459-465. Epub 2016 Apr 16.

Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, 48109.

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http://dx.doi.org/10.1016/j.neuroimage.2016.04.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912854PMC
July 2016

Reduced Nav1.6 Sodium Channel Activity in Mice Increases In Vivo Sensitivity to Volatile Anesthetics.

PLoS One 2015 7;10(8):e0134960. Epub 2015 Aug 7.

Department of Anesthesiology, University of Michigan, 7433 Medical Science Building 1, 1150, West Medical Center Drive, Ann Arbor, Michigan, United States of America; Center for Consciousness Science, University of Michigan, Ann Arbor, Michigan, United States of America; Neuroscience Graduate Program, University of Michigan, Ann Arbor, Michigan, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134960PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529172PMC
May 2016

Anesthetizing the Self: The Neurobiology of Humbug.

Authors:
George A Mashour

Anesthesiology 2016 Apr;124(4):747-9

From the Department of Anesthesiology, Center for Consciousness Science, and Neuroscience Graduate Program, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000001028DOI Listing
April 2016

Perioperative stroke.

Can J Anaesth 2016 Feb 21;63(2):193-204. Epub 2015 Sep 21.

Department of Anesthesiology, University of Michigan Health System, University Hospital 1H247, 1500 East Medical Center Drive, SPC 5048, Ann Arbor, MI, 48109, USA.

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http://dx.doi.org/10.1007/s12630-015-0494-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720532PMC
February 2016

Functional and Topological Conditions for Explosive Synchronization Develop in Human Brain Networks with the Onset of Anesthetic-Induced Unconsciousness.

Front Comput Neurosci 2016 21;10. Epub 2016 Jan 21.

Department of Anesthesiology, University of Michigan Medical SchoolAnn Arbor, MI, USA; Center for Consciousness Science, University of Michigan Medical SchoolAnn Arbor, MI, USA.

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http://dx.doi.org/10.3389/fncom.2016.00001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720783PMC
February 2016

Influence of Ventilation Strategies and Anesthetic Techniques on Regional Cerebral Oximetry in the Beach Chair Position: A Prospective Interventional Study with a Randomized Comparison of Two Anesthetics.

Anesthesiology 2015 Oct;123(4):765-74

From the Department of Anesthesiology (P.P., A.D., A.A., M.N., A.S., M.H., G.A.M.) and Department of Orthopedic Surgery (B.S.M.), University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000000798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573359PMC
October 2015

Alerting thresholds for the prevention of intraoperative awareness with explicit recall: a secondary analysis of the Michigan Awareness Control Study.

Eur J Anaesthesiol 2015 May;32(5):346-53

From the Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan (AMS, SK, KKT, JCV, GAM), Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri (MSA) and Department of Biomedical Engineering, Wayne State University, Detroit, Michigan, USA (JMC).

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May 2015

Noble path to oblivion: molecular and neurophysiological mechanisms of xenon.

Authors:
George A Mashour

Anesthesiology 2015 May;122(5):971-3

From the Department of Anesthesiology, Neuroscience Graduate Program, Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, Michigan.

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May 2015

Intraoperative awareness risk, anesthetic sensitivity, and anesthetic management for patients with natural red hair: a matched cohort study.

Can J Anaesth 2015 Apr 14;62(4):345-55. Epub 2015 Feb 14.

Department of Anesthesiology, Washington University in Saint Louis, School of Medicine, Campus Box 8054, 660 S. Euclid Ave., Saint Louis, MO, 63110, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661058PMC
April 2015

General relationship of global topology, local dynamics, and directionality in large-scale brain networks.

PLoS Comput Biol 2015 Apr 14;11(4):e1004225. Epub 2015 Apr 14.

Department of Anesthesiology, Center for Consciousness Science and Neuroscience Graduate Program, University of Michigan Medical School, Ann Arbor, Michigan, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397097PMC
April 2015

Neurophysiological correlates of sevoflurane-induced unconsciousness.

Anesthesiology 2015 Feb;122(2):307-16

From the Department of Anesthesiology (S.B.-M., V.T., G.V., A.A., D.R., B.S., E.J., G.A.M.) and Neuroscience Graduate Program (G.A.M.), Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000000482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301983PMC
February 2015

Assessing levels of consciousness with symbolic analysis.

Philos Trans A Math Phys Eng Sci 2015 Feb;373(2034)

Center for Consciousness Science, Department of Anesthesiology, Neuroscience Graduate Program, University of Michigan Medical School, 1500 East Medical Center Drive, Ann Arbor, MI 48109-5048, USA.

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February 2015

Psychological sequelae of surgery in a prospective cohort of patients from three intraoperative awareness prevention trials.

Anesth Analg 2015 Jan;120(1):87-95

From the *Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri; †Department of Psychology, Washington University in St. Louis, St. Louis, Missouri; ‡Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan; §Department of Anesthesiology, Washington University in St. Louis, St. Louis, Missouri; ∥Department of Anesthesia and Perioperative Medicine, University of Manitoba, Winnipeg, Manitoba, Canada; #Department of Psychology and Community Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada; and **Department of Anesthesiology and Surgery, Washington University in St. Louis, St. Louis, Missouri.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535987PMC
January 2015

Coupled flip-flop model for REM sleep regulation in the rat.

PLoS One 2014 10;9(4):e94481. Epub 2014 Apr 10.

Department of Mathematics, University of Michigan, Ann Arbor, Michigan, United States of America; Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America; Neuroscience Graduate Program, University of Michigan, Ann Arbor, Michigan, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983214PMC
December 2014

Mind the gap: attitudes towards intraoperative brain monitoring.

Anesth Analg 2014 Nov;119(5):1022-5

From the *Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri, and †Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan.

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November 2014

Perioperative care of patients at high risk for stroke during or after non-cardiac, non-neurologic surgery: consensus statement from the Society for Neuroscience in Anesthesiology and Critical Care*.

J Neurosurg Anesthesiol 2014 Oct;26(4):273-85

*Departments of Anesthesiology and Neurosurgery, University of Michigan, Ann Arbor, MI †Departments of Anesthesiology, Neurology, and Neurosurgery, University of Kansas, Kansas City, KS ‡Department of Anesthesiology, University of Florida, Gainesville, FL §Department of Anesthesia and Perioperative Care, University of California, San Francisco, CA.

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October 2014

Subgraph "backbone" analysis of dynamic brain networks during consciousness and anesthesia.

PLoS One 2013 15;8(8):e70899. Epub 2013 Aug 15.

Department of Physics, Pohang University of Science and Technology, Pohang-si, Gyeongsangbuk-do, South Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744550PMC
September 2014

Postoperative delirium: disconnecting the network?

Anesthesiology 2014 Aug;121(2):214-6

From the Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan (G.A.M.); and Department of Anesthesiology and Cardiothoracic Intensive Care, Washington University School of Medicine, St. Louis, Missouri (M.S.A.).

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August 2014

Dementia and sensitivity to anesthetics.

Can J Anaesth 2014 Jul 29;61(7):599-604. Epub 2014 Apr 29.

Department of Anesthesiology, University Hospital, University of Michigan, 1H247, 1500 E. Medical Center Dr., SPC-5048, Ann Arbor, MI, 48109-5048, USA,

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http://dx.doi.org/10.1007/s12630-014-0166-1DOI Listing
July 2014

Psychological trajectories after intraoperative awareness with explicit recall.

Anesth Analg 2014 Jul;119(1):1-3

From the Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan and Department of Anesthesiology, Washington University, St. Louis, Missouri.

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July 2014

Top-down mechanisms of anesthetic-induced unconsciousness.

Authors:
George A Mashour

Front Syst Neurosci 2014 23;8:115. Epub 2014 Jun 23.

Neuroscience Graduate Program, Department of Anesthesiology, Center for Consciousness Science, University of Michigan Medical School Ann Arbor, MI, USA.

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http://dx.doi.org/10.3389/fnsys.2014.00115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066704PMC
July 2014

Electroencephalographic effects of ketamine on power, cross-frequency coupling, and connectivity in the alpha bandwidth.

Front Syst Neurosci 2014 1;8:114. Epub 2014 Jul 1.

Department of Anesthesiology, Center for Consciousness Science, University of Michigan Medical School Ann Arbor, MI, USA ; Neuroscience Graduate Program, University of Michigan Medical School Ann Arbor, MI, USA.

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July 2014

In reply.

Anesthesiology 2014 Jun;120(6):1522-3

University of Michigan Medical School, Ann Arbor, Michigan (G.A.M.).

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June 2014

Postoperative delirium in a substudy of cardiothoracic surgical patients in the BAG-RECALL clinical trial.

Anesth Analg 2014 Apr;118(4):809-17

From the *Department of Anesthesiology, Washington University School of Medicine; †Department of Mathematics, Washington University in Saint Louis, Saint Louis, Missouri; and ‡Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012920PMC
April 2014

Perioperative metoprolol and risk of stroke after noncardiac surgery.

Anesthesiology 2013 Dec;119(6):1340-6

* Assistant Professor and Associate Chair for Faculty Affairs, § Robert B. Sweet Professor and Chair, ∥ Director of Statistical Core, Department of Anesthesiology, # Associate Professor, Department of Internal Medicine, ‡ Resident in Anesthesiology, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan. † Resident in Anesthesiology, Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts. ** Medical Student, Department of Anesthesiology, University of Michigan Medical School. †† Assistant Professor, Director, Center for Perioperative Outcomes Research, Department of Anesthesiology, University of Michigan.

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December 2013

Reconfiguration of network hub structure after propofol-induced unconsciousness.

Anesthesiology 2013 Dec;119(6):1347-59

Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873632PMC
December 2013

Altered states: psychedelics and anesthetics.

Anesthesiology 2013 Dec;119(6):1255-60

* Resident, † Associate Chair for Faculty Affairs, Associate Professor of Anesthesiology and Neurosurgery, Department of Anesthesiology; Faculty, Neuroscience Graduate Program, University of Michigan, Ann Arbor, Michigan.

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December 2013

Cognitive unbinding: a neuroscientific paradigm of general anesthesia and related states of unconsciousness.

Authors:
George A Mashour

Neurosci Biobehav Rev 2013 Dec 26;37(10 Pt 2):2751-9. Epub 2013 Sep 26.

Associate Professor of Anesthesiology, Faculty of Neuroscience Graduate Program, University of Michigan Medical School, 1500 East Medical Center Drive, 1H247 University Hospital/SPC-5048, Ann Arbor, MI 48109-5048, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870022PMC
December 2013

Increased risk of intraoperative awareness in patients with a history of awareness.

Anesthesiology 2013 Dec;119(6):1275-83

* Medical Student and Predoctoral Research Trainee, Division of Cardiothoracic Anesthesiology and Department of Anesthesiology, ‖ Assistant Professor of Anesthesiology, Department of Anesthesiology, §§ Professor, Division Chief, and Director of INQUIRI, Division of Cardiothoracic Anesthesiology, Washington University School of Medicine, Saint Louis, Missouri. † Research Assistant Professor, ‡‡ Henry E. Mallinckrodt Professor and Department Head, University School of Medicine, Saint Louis, Missouri. ‡ Assistant Professor, Division of Biostatistics, Department of Mathematics, Washington University in Saint Louis, Saint Louis, Missouri. § Statistician Lead, ‖‖ Associate Chair for Faculty Affairs; Associate Professor of Anesthesiology and Neurosurgery; Faculty, Neuroscience Graduate Program, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan. # Associate Professor of Anesthesia and Critical Care, Department of Anesthesiology, University of Chicago, Chicago, Illinois. ** Professor and Department Head, †† Research Technician, Department of Anesthesiology and Perioperative Medicine, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.

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December 2013

Consciousness and the 21st century operating room.

Authors:
George A Mashour

Anesthesiology 2013 Nov;119(5):1003-5

Department of Anesthesiology, Neuroscience Graduate Program, University of Michigan Medical School, Ann Arbor, Michigan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823752PMC
November 2013

Consciousness and responsiveness: lessons from anaesthesia and the vegetative state.

Curr Opin Anaesthesiol 2013 Aug;26(4):444-9

Coma Science Group, Cyclotron Research Centre and Neurology Department, University of Liege and CHU Sart Tilman, Liege, Belgium.

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http://dx.doi.org/10.1097/ACO.0b013e3283628b5dDOI Listing
August 2013

Surge of neurophysiological coherence and connectivity in the dying brain.

Proc Natl Acad Sci U S A 2013 Aug 12;110(35):14432-7. Epub 2013 Aug 12.

Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1073/pnas.1308285110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3761619PMC
August 2013

Consciousness, anesthesia, and neural synchrony.

Authors:
George A Mashour

Anesthesiology 2013 Jul;119(1):7-9

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July 2013

General and specific consciousness: a first-order representationalist approach.

Front Psychol 2013 16;4:407. Epub 2013 Jul 16.

Whitney Humanities Center, Yale University New Haven, CT, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712269PMC
July 2013

Disruption of frontal-parietal communication by ketamine, propofol, and sevoflurane.

Anesthesiology 2013 Jun;118(6):1264-75

Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan 48109-5048, USA.

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http://dx.doi.org/10.1097/ALN.0b013e31829103f5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346246PMC
June 2013

Evolution of consciousness: phylogeny, ontogeny, and emergence from general anesthesia.

Proc Natl Acad Sci U S A 2013 Jun 10;110 Suppl 2:10357-64. Epub 2013 Jun 10.

Department of Anesthesiology, Neuroscience Graduate Program, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1073/pnas.1301188110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690605PMC
June 2013

Postoperative recovery with bispectral index versus anesthetic concentration-guided protocols.

Anesthesiology 2013 May;118(5):1113-22

Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1097/ALN.0b013e31828604abDOI Listing
May 2013

Altered cortical communication in amyotrophic lateral sclerosis.

Neurosci Lett 2013 May 6;543:172-6. Epub 2013 Apr 6.

Department of Anesthesiology, University of Michigan Medical School, 7433 Med Sci I, 1150 West Medical Center Drive, Ann Arbor, MI 48105, USA.

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http://dx.doi.org/10.1016/j.neulet.2013.03.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716378PMC
May 2013

In reply.

Anesthesiology 2013 May;118(5):1235-7

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May 2013

Assessment of intraoperative awareness with explicit recall: a comparison of 2 methods.

Anesth Analg 2013 Apr 4;116(4):889-91. Epub 2013 Mar 4.

Division of Neuroanesthesiology, Department of Anesthesiology, University of Michigan Medical School, 1H247 UH/SPC-5048, 1500 East Medical Center Drive, Ann Arbor, MI 48109-5048, USA.

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April 2013

The incidence of intraoperative awareness in the UK: under the rate or under the radar?

Br J Anaesth 2013 Apr 12;110(4):494-7. Epub 2013 Mar 12.

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http://dx.doi.org/10.1093/bja/aet012DOI Listing
April 2013

Capturing covert consciousness.

Lancet 2013 Jan;381(9863):271-2

Department of Anesthesiology, University of Michigan, Ann Arbor, MI 48109-5048, USA.

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January 2013