George A Mashour

George A Mashour

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George A Mashour

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Altered Global Brain Signal during Physiologic, Pharmacologic, and Pathologic States of Unconsciousness in Humans and Rats.

Anesthesiology 2020 Jun;132(6):1392-1406

From the Department of Anesthesiology, Huashan Hospital, Fudan University, Shanghai, China (J.Z., Y.C., J.X.) the Department of Anesthesiology and Center for Consciousness Science, University of Michigan, Ann Arbor, Michigan (S.T., Z.H., G.A.M., A.G.H.) Institute of Mental Health Research (S.F., G.N.) School of Psychology (S.F.), University of Ottawa, Ottawa, Canada Department of Psychology, University of Montreal, Montreal, Canada (S.F., J.D.) Functional Neuroimaging Unit, Institute of Geriatrics, University of Montréal, Montréal, Canada (S.F., J.D.) McConnell Brain Imaging Center, Montreal Neurological Institute, McGill University, Montreal, Canada (J.D.) Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China (J.W., X.W., Y.M.) Mental Health Center, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China (J.Z., G.N.) School of Psychology, South China Normal University, Guangzhou, Guangdong, China (P.Q.).

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http://dx.doi.org/10.1097/ALN.0000000000003197DOI Listing
June 2020

Activation of Preoptic GABAergic or Glutamatergic Neurons Modulates Sleep-Wake Architecture, but Not Anesthetic State Transitions.

Curr Biol 2020 Mar 20;30(5):779-787.e4. Epub 2020 Feb 20.

Department of Anesthesiology, University of Michigan, 7433 Medical Science Building 1, 1150 West Medical Center Drive, Ann Arbor, MI 48109-5615, USA; Center for Consciousness Science, University of Michigan, Ann Arbor, MI 48109, USA; Neuroscience Graduate Program, University of Michigan, 4137 Undergraduate Science Building, 204 Washtenaw Avenue, Ann Arbor, MI 48109-2215, USA.

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http://dx.doi.org/10.1016/j.cub.2019.12.063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156032PMC
March 2020

Conscious Processing and the Global Neuronal Workspace Hypothesis.

Neuron 2020 03;105(5):776-798

Collège de France, 11 Place Marcelin Berthelot, 75005 Paris, France; Cognitive Neuroimaging Unit, CEA, INSERM, Université Paris-Sud, Université Paris-Saclay, NeuroSpin Center, 91191 Gif/Yvette, France. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2020.01.026DOI Listing
March 2020

Temporal circuit of macroscale dynamic brain activity supports human consciousness.

Sci Adv 2020 03 11;6(11):eaaz0087. Epub 2020 Mar 11.

Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1126/sciadv.aaz0087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065875PMC
March 2020

Pharmacologically informed machine learning approach for identifying pathological states of unconsciousness via resting-state fMRI.

Neuroimage 2020 02 29;206:116316. Epub 2019 Oct 29.

Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, USA; Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI, USA; Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2019.116316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981054PMC
February 2020

Targeting network hubs with noninvasive brain stimulation in patients with fibromyalgia.

Pain 2020 01;161(1):43-46

Department of Anesthesiology, University of Michigan, Ann Arbor, MI, United States.

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http://dx.doi.org/10.1097/j.pain.0000000000001696DOI Listing
January 2020

Measuring team science: Associations between a clinical-translational science institute and investigator ego networks.

J Clin Transl Sci 2019 Dec;2(6):363-370

Michigan Institute for Clinical and Health Research, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1017/cts.2019.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676646PMC
December 2019

Are There Common Network-level Correlates of the Anesthetized Brain in Infants and Adults?

Anesthesiology 2019 12;131(6):1202-1204

From the Department of Anesthesiology (M.P.P., G.A.M.) the Center for Consciousness Science (M.P.P., G.A.M.) the Neuroscience Graduate Program (G.A.M.), University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000002993DOI Listing
December 2019

The Biology of General Anesthesia from Paramecium to Primate.

Curr Biol 2019 11;29(22):R1199-R1210

Department of Anesthesiology, University of Michigan, 7433 Medical Science Building 1, 1150 West Medical Center Drive, Ann Arbor, MI 48109, USA; Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Neuroscience Graduate Program, University of Michigan Medical School, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2019.09.071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902878PMC
November 2019

Role of cortical feedback signalling in consciousness and anaesthetic-induced unconsciousness.

Authors:
George A Mashour

Br J Anaesth 2019 10 1;123(4):404-405. Epub 2019 Aug 1.

Center for Consciousness Science, Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bja.2019.07.001DOI Listing
October 2019

Role of Voltage-Gated Sodium Channels in the Mechanism of Ether-Induced Unconsciousness.

Pharmacol Rev 2019 10;71(4):450-466

Departments of Pharmacology (N.D.) and Anesthesiology (G.A.M.), Center for Consciousness Science (N.D., G.A.M.), and Neuroscience Graduate Program (J.M.H., G.A.M.), University of Michigan, Ann Arbor, Michigan

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http://dx.doi.org/10.1124/pr.118.016592DOI Listing
October 2019

Uncovering covert stroke in surgical patients.

Lancet 2019 09 15;394(10203):982-984. Epub 2019 Aug 15.

Department of Anesthesiology and Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(19)31770-2DOI Listing
September 2019

Cortical dynamics during psychedelic and anesthetized states induced by ketamine.

Neuroimage 2019 08 5;196:32-40. Epub 2019 Apr 5.

Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, United States; Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, United States; Neuroscience Graduate Program, University of Michigan Medical School, Ann Arbor, United States.

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http://dx.doi.org/10.1016/j.neuroimage.2019.03.076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559852PMC
August 2019

Paradoxical lucidity: A potential paradigm shift for the neurobiology and treatment of severe dementias.

Alzheimers Dement 2019 08 19;15(8):1107-1114. Epub 2019 Jun 19.

Department of Family Medicine, Rush Medical College, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.jalz.2019.04.002DOI Listing
August 2019

Modern Anesthetic Ethers Demonstrate Quantum Interactions with Entangled Photons.

Sci Rep 2019 08 5;9(1):11351. Epub 2019 Aug 5.

Department of Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA.

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http://www.nature.com/articles/s41598-019-47651-1
Publisher Site
http://dx.doi.org/10.1038/s41598-019-47651-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683176PMC
August 2019

Pharmacologic Unmasking of Neurologic Deficits: A Stress Test for the Brain.

Anesthesiology 2019 Jul;131(1):5-6

From the Department of Anesthesiology, Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000002775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586480PMC
July 2019

Dynamic Cortical Connectivity during General Anesthesia in Healthy Volunteers.

Anesthesiology 2019 06;130(6):870-884

From the Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan (D.L., P.E.V., G.A.M.) the Department of Anesthesiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania (M.B.K.) the Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri (M.S.A.). From the Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan From the Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan From the Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan From the Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan From the Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan From the Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan From the Department of Anesthesiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania From the Department of Anesthesiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania From the Department of Anesthesiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania From the Department of Anesthesiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania From the Department of Anesthesiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania From the Department of Anesthesiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania From the Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri From the Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri From the Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri.

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http://dx.doi.org/10.1097/ALN.0000000000002656DOI Listing
June 2019

Dynamic Cortical Connectivity during General Anesthesia in Surgical Patients.

Anesthesiology 2019 06;130(6):885-897

From the Department of Anesthesiology (P.E.V., D.L., M.Z., A.P.L., K.I.I., A.M.M., G.A.M.) the Center for Consciousness Science (P.E.V., D.L., G.A.M.) the Neuroscience Graduate Program (G.A.M.), University of Michigan Medical School Ann Arbor, Michigan the Department of Psychology, University of Michigan, Ann Arbor, Michigan (K.I.I.).

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http://dx.doi.org/10.1097/ALN.0000000000002677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520139PMC
June 2019

Independent discussion sections for improving inferential reproducibility in published research.

Br J Anaesth 2019 04 22;122(4):413-420. Epub 2019 Jan 22.

Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1016/j.bja.2018.12.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435840PMC
April 2019

General Anesthesia and the Cortex: Communication Breakdown?

Authors:
George A Mashour

Anesthesiology 2019 04;130(4):526-527

From the Center for Consciousness Science, Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000002636DOI Listing
April 2019

Escape From Oblivion: Neural Mechanisms of Emergence From General Anesthesia.

Anesth Analg 2019 04;128(4):726-736

Department of Anesthesiology, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1213/ANE.0000000000004006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885009PMC
April 2019

General Anesthesia Does Not Have Persistent Effects on Attention in Rodents.

Front Behav Neurosci 2019 17;13:76. Epub 2019 Apr 17.

Department of Anesthesiology, University of Michigan, Ann Arbor, MI, United States.

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http://dx.doi.org/10.3389/fnbeh.2019.00076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478802PMC
April 2019

Relationship of critical dynamics, functional connectivity, and states of consciousness in large-scale human brain networks.

Neuroimage 2019 03 6;188:228-238. Epub 2018 Dec 6.

Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, United States; Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI, United States. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2018.12.011DOI Listing
March 2019

Role of Network Science in the Study of Anesthetic State Transitions.

Anesthesiology 2018 11;129(5):1029-1044

From the Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000002228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191341PMC
November 2018

Highways of the Brain, Traffic of the Mind.

Authors:
George A Mashour

Anesthesiology 2018 11;129(5):869-871

From the Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000002385DOI Listing
November 2018

Increasing Role of Maternal Immune Activation in Neurodevelopmental Disorders.

Front Behav Neurosci 2018 5;12:230. Epub 2018 Oct 5.

Center for Consciousness Science, Department of Anesthesiology, University of Michigan, Ann Arbor, MI, United States.

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https://www.frontiersin.org/article/10.3389/fnbeh.2018.00230
Publisher Site
http://dx.doi.org/10.3389/fnbeh.2018.00230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182081PMC
October 2018

Consciousness and Personhood in Medical Care.

Front Hum Neurosci 2018 2;12:306. Epub 2018 Aug 2.

Department of Anesthesiology, Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI, United States.

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http://dx.doi.org/10.3389/fnhum.2018.00306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082939PMC
August 2018

Mechanisms of hysteresis in human brain networks during transitions of consciousness and unconsciousness: Theoretical principles and empirical evidence.

PLoS Comput Biol 2018 08 30;14(8):e1006424. Epub 2018 Aug 30.

Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1006424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135517PMC
August 2018

Differentiating Drug-related and State-related Effects of Dexmedetomidine and Propofol on the Electroencephalogram.

Anesthesiology 2018 07;129(1):22-36

From the Turku PET Centre, University of Turku and the Hospital District of Southwest Finland, Turku, Finland (A.S., K.K., J.L., A.M., H.S.) the Department of Perioperative Services, Intensive Care and Pain Medicine, Turku University Hospital, Turku, Finland (A.S., R.E.K., M.K., A.M., H.S.) the Department of Psychology and Speech-Language Pathology, and Turku Brain and Mind Center (R.E.K., K.V., A.R.) the Department of Pharmacology, Drug Development and Therapeutics (H.S.) University of Turku, Turku, Finland; the Department of Anesthesiology, Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, Michigan (D.L., G.A.M.) the Department of Anesthesiology and Intensive Care, Oulu University Hospital, Oulu, Finland (K.K.) the Department of Intensive Care, Tampere University Hospital, Tampere, Finland (J.L.) the Department of Clinical Medicine, Biostatistics, University of Turku and Turku University Hospital, Turku, Finland (T.V.) the Department of Cognitive Neuroscience and Philosophy, School of Bioscience, University of Skövde, Skövde, Sweden (K.V., A.R.).

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http://dx.doi.org/10.1097/ALN.0000000000002192DOI Listing
July 2018

Differential Role of Prefrontal and Parietal Cortices in Controlling Level of Consciousness.

Curr Biol 2018 07 21;28(13):2145-2152.e5. Epub 2018 Jun 21.

Department of Anesthesiology, University of Michigan, 7433 Medical Science Building 1, 1150 West Medical Center Drive, Ann Arbor, MI 48109-5615, USA; Center for Consciousness Science, University of Michigan, Ann Arbor, MI 48109, USA; Neuroscience Graduate Program, University of Michigan, 4137 Undergraduate Science Building, 204 Washtenaw Avenue, Ann Arbor, MI 48109-2215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2018.05.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039257PMC
July 2018

Right now, in the right way: U. S. Food and Drug Administration's expanded access program and patient rights.

J Clin Transl Sci 2018 Jun;2(3):115-117

Michigan Institute for Clinical and Health Research (MICHR), Office of Research, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1017/cts.2018.318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202008PMC
June 2018

Neurologic Considerations and Complications Related to Liver Transplantation.

Anesthesiology 2018 05;128(5):1008-1014

From the Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000002148DOI Listing
May 2018

The controversial correlates of consciousness.

Authors:
George A Mashour

Science 2018 05;360(6388):493-494

Center for Consciousness Science, Department of Anesthesiology, Neuroscience Graduate Program, University of Michigan Medical School, University Hospital, 1H247, 1500 East Medical Center Drive, SPC-5048, Ann Arbor, MI 48109-5048, USA.

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http://dx.doi.org/10.1126/science.aat5616DOI Listing
May 2018

Neural Correlates of Unconsciousness in Large-Scale Brain Networks.

Trends Neurosci 2018 03 3;41(3):150-160. Epub 2018 Feb 3.

Neuroscience Graduate Program, Center for Consciousness Science, Department of Anesthesiology, University of Michigan Medical School, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1016/j.tins.2018.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835202PMC
March 2018

Systems Neuroscience: The Exciting Journey to Oblivion.

Curr Biol 2018 03;28(5):R223-R224

Center for Consciousness Science, University of Michigan, Ann Arbor, MI 48109, USA; Department of Anesthesiology and Critical Care, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.cub.2018.01.074DOI Listing
March 2018

Bottom-Up and Top-Down Mechanisms of General Anesthetics Modulate Different Dimensions of Consciousness.

Front Neural Circuits 2017 20;11:44. Epub 2017 Jun 20.

Department of Anesthesiology, University of MichiganAnn Arbor, MI, United States.

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http://dx.doi.org/10.3389/fncir.2017.00044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476707PMC
February 2018

Timescales of Intrinsic BOLD Signal Dynamics and Functional Connectivity in Pharmacologic and Neuropathologic States of Unconsciousness.

J Neurosci 2018 02 31;38(9):2304-2317. Epub 2018 Jan 31.

Department of Anesthesiology and Center for Consciousness Science, University of Michigan, Ann Arbor, Michigan 48109 and

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http://dx.doi.org/10.1523/JNEUROSCI.2545-17.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830518PMC
February 2018

Estimating the Integrated Information Measure Phi from High-Density Electroencephalography during States of Consciousness in Humans.

Front Hum Neurosci 2018 16;12:42. Epub 2018 Feb 16.

Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, United States.

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http://dx.doi.org/10.3389/fnhum.2018.00042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821001PMC
February 2018

Functional Brain Network Mechanism of Hypersensitivity in Chronic Pain.

Sci Rep 2018 01 10;8(1):243. Epub 2018 Jan 10.

Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, 48109, USA.

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http://dx.doi.org/10.1038/s41598-017-18657-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762762PMC
January 2018

Comment on the PODCAST study - Authors' reply.

Lancet 2017 11;390(10110):2346

Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1016/S0140-6736(17)32896-9DOI Listing
November 2017

Adapting the model of consumer behavior to the design of an online health research recruitment tool.

J Clin Transl Sci 2017 Aug 14;1(4):240-245. Epub 2017 Aug 14.

Michigan Institute for Clinical and Health Research, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1017/cts.2017.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890321PMC
August 2017

Toward a science of translational science.

J Clin Transl Sci 2017 Aug 14;1(4):253-255. Epub 2017 Aug 14.

Office of Research, Medical School, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1017/cts.2017.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890312PMC
August 2017

Neurophysiologic Correlates of Ketamine Sedation and Anesthesia: A High-density Electroencephalography Study in Healthy Volunteers.

Anesthesiology 2017 07;127(1):58-69

From the Department of Anesthesiology (P.E.V., T.B.-B., U.L., D.L., H.K., E.J., V.T., A.M.M., B.S.K., P.P., G.A.M.), Center for Consciousness Science (P.E.V., T.B.-B., U.L., D.L., H.K., G.A.M.), and Neuroscience Graduate Program (G.A.M.), University of Michigan Medical School, Ann Arbor, Michigan; and the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois (A.B.P.).

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http://dx.doi.org/10.1097/ALN.0000000000001671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478453PMC
July 2017

Protocol for the Reconstructing Consciousness and Cognition (ReCCognition) Study.

Front Hum Neurosci 2017 7;11:284. Epub 2017 Jun 7.

Department of Anesthesiology and Critical Care, Perelman School of Medicine, University of PennsylvaniaPhiladelphia, PA, United States.

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http://dx.doi.org/10.3389/fnhum.2017.00284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461274PMC
June 2017

Relationship of Topology, Multiscale Phase Synchronization, and State Transitions in Human Brain Networks.

Front Comput Neurosci 2017 30;11:55. Epub 2017 Jun 30.

Center for Consciousness Science, University of Michigan Medical SchoolAnn Arbor, MI, United States.

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http://dx.doi.org/10.3389/fncom.2017.00055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492767PMC
June 2017

Effect of a Clinical and Translational Science Award institute on grant funding in a major research university.

J Clin Transl Sci 2017 Apr 2;1(2):88-93. Epub 2017 Mar 2.

Office of Research, Medical School, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1017/cts.2016.32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444804PMC
April 2017

Network Inefficiency: A Rosetta Stone for the Mechanism of Anesthetic-induced Unconsciousness.

Authors:
George A Mashour

Anesthesiology 2017 03;126(3):366-368

From the Department of Anesthesiology, Center for Consciousness Science, Neuroscience Graduate Program, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000001510DOI Listing
March 2017

Paradoxical Emergence: Administration of Subanesthetic Ketamine during Isoflurane Anesthesia Induces Burst Suppression but Accelerates Recovery.

Anesthesiology 2017 Mar;126(3):482-494

From the Department of Anesthesiology (V.S.H.-W., D.L., G.A.M.), Center of Consciousness Science (V.S.H.-W., D.L., G.A.M.), and Neuroscience Graduate Program (G.A.M.), University of Michigan, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000001512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309196PMC
March 2017

Accelerated Recovery of Consciousness after General Anesthesia Is Associated with Increased Functional Brain Connectivity in the High-Gamma Bandwidth.

Front Syst Neurosci 2017 24;11:16. Epub 2017 Mar 24.

Department of Anesthesiology, University of MichiganAnn Arbor, MI, USA; Center for Consciousness Science, University of MichiganAnn Arbor, MI, USA; Neuroscience Graduate Program, University of MichiganAnn Arbor, MI, USA.

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http://dx.doi.org/10.3389/fnsys.2017.00016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364164PMC
March 2017

Incidence of Connected Consciousness after Tracheal Intubation: A Prospective, International, Multicenter Cohort Study of the Isolated Forearm Technique.

Anesthesiology 2017 02;126(2):214-222

From the Department of Anesthesiology, University of Wisconsin-Madison, Madison, Wisconsin (R.D.S., A.R., C.B., A.H., R.M.B.); Department of Anesthesia, Rambam Healthcare Campus, Haifa, Israel (A.R.); Department of Anesthesiology and Critical Care, Houston Methodist Hospital, Houston, Texas (R.M.B.); Department of Anaesthesia, Waikato Clinical School, University of Auckland, Hamilton, New Zealand (A.G., J.W., J.S.); Department of Anesthesiology; University Hospital RWTH Aachen, Aachen, Germany (A.S., R.R., M.C.); Department of Anesthesia and Intensive Care Medicine, CHU University Hospital of Liège, Liège, Belgium (A.D., G.T., V.B.); University Department of Anesthesia and Intensive Care Medicine, CHR Citadelle and CHU University Hospital of Liège, Liège, Belgium (A.D., G.T., V.B.); Department of Anesthesiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands, (S.T., S.M., A.A.); and Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan (P.E.V., H.F., G.A.M.).

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February 2017

Repertoire of mesoscopic cortical activity is not reduced during anesthesia.

Neuroscience 2016 Dec 14;339:402-417. Epub 2016 Oct 14.

Department of Anesthesiology, Center for Consciousness Science, Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI, United States.

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http://dx.doi.org/10.1016/j.neuroscience.2016.10.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118138PMC
December 2016

Network-level Mechanisms of Ketamine Anesthesia.

Authors:
George A Mashour

Anesthesiology 2016 11;125(5):830-831

From the Department of Anesthesiology, Center for Consciousness Science, Neuroscience Graduate Program, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000001276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5183540PMC
November 2016

Neural Correlates of Wakefulness, Sleep, and General Anesthesia: An Experimental Study in Rat.

Anesthesiology 2016 11;125(5):929-942

From the Department of Anesthesiology (D.P., H.L., G.A.M.), Center for Consciousness Science (D.P., B.H.S., G.A.M.), and Neuroscience Graduate Program (G.A.M.), University of Michigan, Ann Arbor, Michigan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069172PMC
http://dx.doi.org/10.1097/ALN.0000000000001342DOI Listing
November 2016

Neural Correlates of Sevoflurane-induced Unconsciousness Identified by Simultaneous Functional Magnetic Resonance Imaging and Electroencephalography.

Anesthesiology 2016 11;125(5):861-872

From the Departments of Neurology (D.G., G.R., A.T., M.M., R.I.), Anesthesiology (A.R., T.K., P.K., J.P., S.B., A.T., M.M., E.F.K., D.J.), and Neuroradiology (V.R., C.P., C.Z.), Klinikum rechts der Isar der Technischen Universität München, München, Germany; and Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan (G.A.M.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069173PMC
http://dx.doi.org/10.1097/ALN.0000000000001322DOI Listing
November 2016

Disconnecting Consciousness: Is There a Common Anesthetic End Point?

Anesth Analg 2016 11;123(5):1228-1240

From the Department of Anesthesiology, Center for Consciousness Science, University of Michigan, Ann Arbor, Michigan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073005PMC
http://dx.doi.org/10.1213/ANE.0000000000001353DOI Listing
November 2016

Recognition and Management of Perioperative Stroke in Hospitalized Patients.

A A Case Rep 2016 Aug;7(3):55-6

From the *Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan; †University of Michigan Medical School, Ann Arbor, Michigan; and ‡Department of Anesthesia, University of California San Francisco School of Medicine, San Francisco, California.

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http://dx.doi.org/10.1213/XAA.0000000000000342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975429PMC
August 2016

The Neurobiology of Anesthetic Emergence.

J Neurosurg Anesthesiol 2016 Jul;28(3):250-5

Department of Anesthesiology, Division of Neuroanesthesiology, Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI.

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http://dx.doi.org/10.1097/ANA.0000000000000212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752918PMC
July 2016

Disruption of corticocortical information transfer during ketamine anesthesia in the primate brain.

Neuroimage 2016 07 16;134:459-465. Epub 2016 Apr 16.

Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, 48109.

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http://dx.doi.org/10.1016/j.neuroimage.2016.04.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912854PMC
July 2016

Reduced Nav1.6 Sodium Channel Activity in Mice Increases In Vivo Sensitivity to Volatile Anesthetics.

PLoS One 2015 7;10(8):e0134960. Epub 2015 Aug 7.

Department of Anesthesiology, University of Michigan, 7433 Medical Science Building 1, 1150, West Medical Center Drive, Ann Arbor, Michigan, United States of America; Center for Consciousness Science, University of Michigan, Ann Arbor, Michigan, United States of America; Neuroscience Graduate Program, University of Michigan, Ann Arbor, Michigan, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134960PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529172PMC
May 2016

Anesthetizing the Self: The Neurobiology of Humbug.

Authors:
George A Mashour

Anesthesiology 2016 Apr;124(4):747-9

From the Department of Anesthesiology, Center for Consciousness Science, and Neuroscience Graduate Program, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000001028DOI Listing
April 2016

Perioperative stroke.

Can J Anaesth 2016 Feb 21;63(2):193-204. Epub 2015 Sep 21.

Department of Anesthesiology, University of Michigan Health System, University Hospital 1H247, 1500 East Medical Center Drive, SPC 5048, Ann Arbor, MI, 48109, USA.

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http://dx.doi.org/10.1007/s12630-015-0494-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720532PMC
February 2016

Functional and Topological Conditions for Explosive Synchronization Develop in Human Brain Networks with the Onset of Anesthetic-Induced Unconsciousness.

Front Comput Neurosci 2016 21;10. Epub 2016 Jan 21.

Department of Anesthesiology, University of Michigan Medical SchoolAnn Arbor, MI, USA; Center for Consciousness Science, University of Michigan Medical SchoolAnn Arbor, MI, USA.

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http://dx.doi.org/10.3389/fncom.2016.00001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720783PMC
February 2016

Influence of Ventilation Strategies and Anesthetic Techniques on Regional Cerebral Oximetry in the Beach Chair Position: A Prospective Interventional Study with a Randomized Comparison of Two Anesthetics.

Anesthesiology 2015 Oct;123(4):765-74

From the Department of Anesthesiology (P.P., A.D., A.A., M.N., A.S., M.H., G.A.M.) and Department of Orthopedic Surgery (B.S.M.), University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000000798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573359PMC
October 2015

Alerting thresholds for the prevention of intraoperative awareness with explicit recall: a secondary analysis of the Michigan Awareness Control Study.

Eur J Anaesthesiol 2015 May;32(5):346-53

From the Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan (AMS, SK, KKT, JCV, GAM), Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri (MSA) and Department of Biomedical Engineering, Wayne State University, Detroit, Michigan, USA (JMC).

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http://dx.doi.org/10.1097/EJA.0000000000000123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737525PMC
May 2015

Noble path to oblivion: molecular and neurophysiological mechanisms of xenon.

Authors:
George A Mashour

Anesthesiology 2015 May;122(5):971-3

From the Department of Anesthesiology, Neuroscience Graduate Program, Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000000636DOI Listing
May 2015

Intraoperative awareness risk, anesthetic sensitivity, and anesthetic management for patients with natural red hair: a matched cohort study.

Can J Anaesth 2015 Apr 14;62(4):345-55. Epub 2015 Feb 14.

Department of Anesthesiology, Washington University in Saint Louis, School of Medicine, Campus Box 8054, 660 S. Euclid Ave., Saint Louis, MO, 63110, USA.

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http://dx.doi.org/10.1007/s12630-014-0305-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661058PMC
April 2015

General relationship of global topology, local dynamics, and directionality in large-scale brain networks.

PLoS Comput Biol 2015 Apr 14;11(4):e1004225. Epub 2015 Apr 14.

Department of Anesthesiology, Center for Consciousness Science and Neuroscience Graduate Program, University of Michigan Medical School, Ann Arbor, Michigan, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1004225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397097PMC
April 2015

Neurophysiological correlates of sevoflurane-induced unconsciousness.

Anesthesiology 2015 Feb;122(2):307-16

From the Department of Anesthesiology (S.B.-M., V.T., G.V., A.A., D.R., B.S., E.J., G.A.M.) and Neuroscience Graduate Program (G.A.M.), Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/ALN.0000000000000482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301983PMC
February 2015

Assessing levels of consciousness with symbolic analysis.

Philos Trans A Math Phys Eng Sci 2015 Feb;373(2034)

Center for Consciousness Science, Department of Anesthesiology, Neuroscience Graduate Program, University of Michigan Medical School, 1500 East Medical Center Drive, Ann Arbor, MI 48109-5048, USA.

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http://rsta.royalsocietypublishing.org/content/roypta/373/20
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http://dx.doi.org/10.1098/rsta.2014.0117DOI Listing
February 2015

Psychological sequelae of surgery in a prospective cohort of patients from three intraoperative awareness prevention trials.

Anesth Analg 2015 Jan;120(1):87-95

From the *Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri; †Department of Psychology, Washington University in St. Louis, St. Louis, Missouri; ‡Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan; §Department of Anesthesiology, Washington University in St. Louis, St. Louis, Missouri; ∥Department of Anesthesia and Perioperative Medicine, University of Manitoba, Winnipeg, Manitoba, Canada; #Department of Psychology and Community Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada; and **Department of Anesthesiology and Surgery, Washington University in St. Louis, St. Louis, Missouri.

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http://dx.doi.org/10.1213/ANE.0000000000000498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535987PMC
January 2015

Coupled flip-flop model for REM sleep regulation in the rat.

PLoS One 2014 10;9(4):e94481. Epub 2014 Apr 10.

Department of Mathematics, University of Michigan, Ann Arbor, Michigan, United States of America; Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America; Neuroscience Graduate Program, University of Michigan, Ann Arbor, Michigan, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983214PMC
December 2014

Mind the gap: attitudes towards intraoperative brain monitoring.

Anesth Analg 2014 Nov;119(5):1022-5

From the *Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri, and †Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan.

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http://dx.doi.org/10.1213/ANE.0000000000000414DOI Listing
November 2014

Perioperative care of patients at high risk for stroke during or after non-cardiac, non-neurologic surgery: consensus statement from the Society for Neuroscience in Anesthesiology and Critical Care*.

J Neurosurg Anesthesiol 2014 Oct;26(4):273-85

*Departments of Anesthesiology and Neurosurgery, University of Michigan, Ann Arbor, MI †Departments of Anesthesiology, Neurology, and Neurosurgery, University of Kansas, Kansas City, KS ‡Department of Anesthesiology, University of Florida, Gainesville, FL §Department of Anesthesia and Perioperative Care, University of California, San Francisco, CA.

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http://dx.doi.org/10.1097/ANA.0000000000000087DOI Listing
October 2014

Postoperative delirium: disconnecting the network?

Anesthesiology 2014 Aug;121(2):214-6

From the Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan (G.A.M.); and Department of Anesthesiology and Cardiothoracic Intensive Care, Washington University School of Medicine, St. Louis, Missouri (M.S.A.).

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http://dx.doi.org/10.1097/ALN.0000000000000330DOI Listing
August 2014

Dementia and sensitivity to anesthetics.

Can J Anaesth 2014 Jul 29;61(7):599-604. Epub 2014 Apr 29.

Department of Anesthesiology, University Hospital, University of Michigan, 1H247, 1500 E. Medical Center Dr., SPC-5048, Ann Arbor, MI, 48109-5048, USA,

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http://dx.doi.org/10.1007/s12630-014-0166-1DOI Listing
July 2014

Psychological trajectories after intraoperative awareness with explicit recall.

Anesth Analg 2014 Jul;119(1):1-3

From the Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan and Department of Anesthesiology, Washington University, St. Louis, Missouri.

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http://dx.doi.org/10.1213/ANE.0000000000000265DOI Listing
July 2014

Top-down mechanisms of anesthetic-induced unconsciousness.

Authors:
George A Mashour

Front Syst Neurosci 2014 23;8:115. Epub 2014 Jun 23.

Neuroscience Graduate Program, Department of Anesthesiology, Center for Consciousness Science, University of Michigan Medical School Ann Arbor, MI, USA.

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http://dx.doi.org/10.3389/fnsys.2014.00115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066704PMC
July 2014

Electroencephalographic effects of ketamine on power, cross-frequency coupling, and connectivity in the alpha bandwidth.

Front Syst Neurosci 2014 1;8:114. Epub 2014 Jul 1.

Department of Anesthesiology, Center for Consciousness Science, University of Michigan Medical School Ann Arbor, MI, USA ; Neuroscience Graduate Program, University of Michigan Medical School Ann Arbor, MI, USA.

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http://dx.doi.org/10.3389/fnsys.2014.00114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076669PMC
July 2014

In reply.

Anesthesiology 2014 Jun;120(6):1522-3

University of Michigan Medical School, Ann Arbor, Michigan (G.A.M.).

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http://dx.doi.org/10.1097/ALN.0000000000000244DOI Listing
June 2014

Postoperative delirium in a substudy of cardiothoracic surgical patients in the BAG-RECALL clinical trial.

Anesth Analg 2014 Apr;118(4):809-17

From the *Department of Anesthesiology, Washington University School of Medicine; †Department of Mathematics, Washington University in Saint Louis, Saint Louis, Missouri; and ‡Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan.

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http://dx.doi.org/10.1213/ANE.0000000000000028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012920PMC
April 2014