Georg Widhalm

Georg Widhalm

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Georg Widhalm

Georg Widhalm

Publications by authors named "Georg Widhalm"

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High-resolution metabolic mapping of gliomas via patch-based super-resolution magnetic resonance spectroscopic imaging at 7T.

Neuroimage 2019 May 14;191:587-595. Epub 2019 Feb 14.

High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria; Christian Doppler Laboratory for Clinical Molecular MR Imaging, Austria. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10538119193010
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http://dx.doi.org/10.1016/j.neuroimage.2019.02.023DOI Listing
May 2019

5-aminolevulinic acid induced protoporphyrin IX (ALA-PpIX) fluorescence guidance in meningioma surgery.

J Neurooncol 2019 Feb 2;141(3):555-565. Epub 2019 Jan 2.

Department of Neurosurgery, Dartmouth Hitchcock Medical Center, 1 Medical Center Drive, Lebanon, NH, 03766, USA.

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http://dx.doi.org/10.1007/s11060-018-03079-7DOI Listing
February 2019

The prognostic value of [I]-vascular endothelial growth factor ([I]-VEGF) in glioma.

Eur J Nucl Med Mol Imaging 2018 12 30;45(13):2396-2403. Epub 2018 Jul 30.

Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1007/s00259-018-4088-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208804PMC
December 2018

Beyond backscattering: optical neuroimaging by BRAD.

Biomed Opt Express 2018 Jun 1;9(6):2476-2494. Epub 2018 May 1.

Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1364/BOE.9.002476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154182PMC
June 2018

Bioimaging and surgery of brain tumors.

Handb Clin Neurol 2017 ;145:535-545

Department of Neurosurgery, Medical University of Vienna, Vienna, Austria; Central Nervous System Tumors Unit, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/B978-0-12-802395-2.00033-XDOI Listing
January 2018

Correlation of immune phenotype with IDH mutation in diffuse glioma.

Neuro Oncol 2017 Oct;19(11):1460-1468

Institute of Neurology, Medical University of Vienna, Vienna, Austria; Department of Medicine I, Medical University of Vienna, Vienna, Austria; Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria; Department of Neurosurgery, Medical University of Vienna, Vienna, Austria; Department of Genome Science, The John Curtin School of Medical Research, The Australian National University, Canberra, Australia; Laboratory of Brain Tumor Biology and Genetics, Service of Neurosurgery & Neuroscience Research Center, Lausanne University Hospital (CHUV), Lausanne, Switzerland.

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http://dx.doi.org/10.1093/neuonc/nox054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737620PMC
October 2017

Combining standard clinical blood values for improving survival prediction in patients with newly diagnosed brain metastases-development and validation of the LabBM score.

Neuro Oncol 2017 Sep;19(9):1255-1262

Department of Medicine I, Medical University of Vienna, Vienna, Austria; Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria; Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland; Biostatistics Division, German Cancer Research Center, Heidelberg, Germany; Department of Neurosurgery, Medical University of Vienna, Vienna, Austria; Department of Radiotherapy, Medical University of Vienna, Vienna, Austria; Department of Pathology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1093/neuonc/now290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570252PMC
September 2017

Tumor infiltrating lymphocytes and PD-L1 expression in brain metastases of small cell lung cancer (SCLC).

J Neurooncol 2016 10 19;130(1):19-29. Epub 2016 Jul 19.

Department of Medicine I and Comprehensive Cancer Center CNS Unit (CCC-CNS), Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s11060-016-2216-8DOI Listing
October 2016

Descriptive statistical analysis of a real life cohort of 2419 patients with brain metastases of solid cancers.

ESMO Open 2016 16;1(2):e000024. Epub 2016 Mar 16.

Department of Medicine I, Medical University of Vienna, Vienna, Austria; Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1136/esmoopen-2015-000024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070252PMC
March 2016

Expression profiling of angiogenesis-related genes in brain metastases of lung cancer and melanoma.

Tumour Biol 2016 Jan 16;37(1):1173-82. Epub 2015 Aug 16.

Department of Medicine 1, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1007/s13277-015-3790-7DOI Listing
January 2016

What is the Surgical Benefit of Utilizing 5-Aminolevulinic Acid for Fluorescence-Guided Surgery of Malignant Gliomas?

Neurosurgery 2015 Nov;77(5):663-73

*Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY; ‡Department of Neurosurgery, Medical University Vienna, Vienna, Austria; §Department of Neurosurgery, University of Munster, Munster, Germany.

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http://dx.doi.org/10.1227/NEU.0000000000000929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615466PMC
November 2015

Programmed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastoma.

Neuro Oncol 2015 Aug 29;17(8):1064-75. Epub 2014 Oct 29.

Institute of Neurology, Medical University of Vienna, Vienna, Austria (A.S.B., G.R., A.W., J.A.H.); Department of Medicine I, Medical University of Vienna, Vienna, Austria (A.S.B., O.R., M.F., A.B., C.C.Z., C.M., M.P.); Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria (A.S.B., B.K., G.W., O.R., G.R., A.W., K.D., M.F., A.B., C.C.Z., C.M., J.A.H., M.P.); Department of Neurosurgery, Medical University of Vienna, Vienna, Austria (B.K., G.W.); Department of Radiotherapy, Medical University of Vienna, Vienna, Austria (K.D.); Department of Neurology, University Hospital Zurich, Zurich, Switzerland (M.W.); Laboratory of Brain Tumor Biology and Genetics, Service of Neurosurgery, Department of Clinical Neurosciences, University Hospital Lausanne (CHUV), Lausanne, Switzerland (S.K., M.E.H.); Neurology Clinic and National Center for Tumor Disease, University of Heidelberg, Heidelberg, Germany (W.W.); Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany (W.W.).

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http://dx.doi.org/10.1093/neuonc/nou307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490866PMC
August 2015

Haematopoietic stem cell transplantation for treatment of primary CNS lymphoma: single-centre experience and literature review.

Eur J Haematol 2015 Jul 23;95(1):75-82. Epub 2015 Mar 23.

Unit for Bone Marrow and Stem Cell Transplantation, Department of Medicine I, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/ejh.12482DOI Listing
July 2015

Density of tumor-infiltrating lymphocytes correlates with extent of brain edema and overall survival time in patients with brain metastases.

Oncoimmunology 2016;5(1):e1057388. Epub 2015 Jun 9.

Department for Medicine I/Clinical Division of Oncology; Medical University of Vienna; Vienna, Austria; Comprehensive Cancer Center - CNS Tumors Unit; Medical University of Vienna; Vienna, Austria.

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http://dx.doi.org/10.1080/2162402X.2015.1057388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760339PMC
June 2015

Differential role of angiogenesis and tumour cell proliferation in brain metastases according to primary tumour type: analysis of 639 cases.

Neuropathol Appl Neurobiol 2015 Feb;41(2):e41-55

Institute of Neurology, Medical University of Vienna, Vienna, Austria; Comprehensive Cancer Center CNS Tumors Unit, Medical University of Vienna, Vienna, Austria; Department of Medicine I, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/nan.12185DOI Listing
February 2015

Tumour-infiltrating lymphocytes and expression of programmed death ligand 1 (PD-L1) in melanoma brain metastases.

Histopathology 2015 Jan 10;66(2):289-99. Epub 2014 Nov 10.

Department of Medicine I, Medical University of Vienna, Vienna, Austria; Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/his.12537DOI Listing
January 2015

A novel protocol of continuous navigation guidance for endoscopic third ventriculostomy.

Neurosurgery 2014 Dec;10 Suppl 4:514-23; discussion 523-4

*Department of Neurosurgery, and ‡Department of Anesthesiology, Medical University of Vienna, Vienna, Austria; §Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1227/NEU.0000000000000518DOI Listing
December 2014

Amplification and overexpression of CMET is a common event in brain metastases of non-small cell lung cancer.

Histopathology 2014 Nov 5;65(5):684-92. Epub 2014 Aug 5.

Department of Internal Medicine 1, Medical University of Vienna, Vienna, Austria; Comprehensive Cancer Center, CNS Unit, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/his.12475DOI Listing
November 2014

Intra-operative visualization of brain tumors with 5-aminolevulinic acid-induced fluorescence.

Authors:
Georg Widhalm

Clin Neuropathol 2014 Jul-Aug;33(4):260-78

Department of Neurosurgery, Institute of Neurology, and Comprehensive Cancer Center - Central Nervous System Tumours Unit (CCC-CNS), Medical University Vienna, Vienna, Austria.

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September 2014

5-Aminolevulinic acid induced fluorescence is a powerful intraoperative marker for precise histopathological grading of gliomas with non-significant contrast-enhancement.

PLoS One 2013 18;8(10):e76988. Epub 2013 Oct 18.

Department of Neurosurgery, Medical University Vienna, Vienna, Austria ; Institute of Neurology, Medical University Vienna, Vienna, Austria ; Comprehensive Cancer Center - Central Nervous System Tumours Unit (CCC-CNS), Medical University Vienna, Vienna, Austria.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0076988PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800004PMC
August 2014

Sorafenib for patients with pretreated recurrent or progressive high-grade glioma: a retrospective, single-institution study.

Anticancer Drugs 2014 Jul;25(6):723-8

aDepartment of Medicine I, Division of Medical Oncology bInstitute of Neurology Departments of cNeurosurgery dRadiotherapy and Radiobiology eComprehensive Cancer Center - Central Nervous System Tumours Unit (CCC-CNS), Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1097/CAD.0000000000000077DOI Listing
July 2014

Alleviation of brain edema and restoration of functional independence by bevacizumab in brain-metastatic breast cancer: a case report.

Breast Care (Basel) 2014 May;9(2):134-6

Department of Medicine I, Medical University of Vienna, Austria ; Comprehensive Cancer Center, CNS Tumors Unit (CCC-CNS), Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1159/000360930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038309PMC
May 2014

Clinical Neuropathology practice news 1-2014: pyrosequencing meets clinical and analytical performance criteria for routine testing of MGMT promoter methylation status in glioblastoma.

Clin Neuropathol 2014 Jan-Feb;33(1):6-14

Department of Medicine I, Medical University of Vienna, Vienna, Division of Pathology, Medical University of Innsbruck, Innsbruck, Comprehensive Cancer Center - CNS Tumors Unit (CCC-CNS), Medical University of Vienna, Vienna, Molecular Diagnostics, Austrian Institute of Technology, Department of Radiotherapy, Department of Neurosurgery, and Institute of Neurology, Medical University of Vienna, Vienna, Austria.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891253PMC
April 2014

PD1 (CD279) and PD-L1 (CD274, B7H1) expression in primary central nervous system lymphomas (PCNSL).

Clin Neuropathol 2014 Jan-Feb;33(1):42-9

Institute of Neurology, Department of Medicine I, Comprehensive Cancer Center, Department of Neurosurgery, and Institute of Clinical Pathology, Medical University of Vienna, Vienna, Austria.

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April 2014

High rate of FGFR1 amplifications in brain metastases of squamous and non-squamous lung cancer.

Lung Cancer 2014 Jan 17;83(1):83-9. Epub 2013 Oct 17.

Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria; Comprehensive Cancer Center Vienna, Central Nervous System Tumours Unit (CCC-CNS), Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2013.10.004DOI Listing
January 2014

Frequent overexpression of ErbB--receptor family members in brain metastases of non-small cell lung cancer patients.

APMIS 2013 Dec 12;121(12):1144-52. Epub 2013 Jun 12.

Institute of Neurology, Medical University of Vienna, Vienna, Austria; Comprehensive Cancer Center, Vienna, Austria.

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http://dx.doi.org/10.1111/apm.12063DOI Listing
December 2013

Clinical neuropathology practice guide 1-2013: molecular subtyping of glioblastoma: ready for clinical use?

Clin Neuropathol 2013 Jan-Feb;32(1):5-8

Institute of Neurology, Department of Medicine I, Medical University of Vienna, Vienna.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664779PMC
April 2013

Computer-assisted and fractal-based morphometric assessment of microvascularity in histological specimens of gliomas.

Sci Rep 2012 29;2:429. Epub 2012 May 29.

Center for Anatomy and Cell Biology, Department of Systematic Anatomy, Medical University of Vienna, Vienna, Austria.

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http://www.nature.com/articles/srep00429
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http://dx.doi.org/10.1038/srep00429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361706PMC
February 2013

Exploratory investigation of eight circulating plasma markers in brain tumor patients.

Neurosurg Rev 2013 Jan 5;36(1):45-55; discussion 55-6. Epub 2012 Jul 5.

Department of Medicine III, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s10143-012-0401-6DOI Listing
January 2013

Brain tumor surgery with 3-dimensional surface navigation.

Neurosurgery 2012 Dec;71(2 Suppl Operative):ons286-94; discussion ons294-5

Department of Neurosurgery, Medical University Vienna, Waehringer Guertel 18-20, Vienna, Austria.

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https://academic.oup.com/ons/article-lookup/doi/10.1227/NEU.
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http://dx.doi.org/10.1227/NEU.0b013e31826a8a75DOI Listing
December 2012

Plasma MicroRNA-21 concentration may be a useful biomarker in glioblastoma patients.

Cancer Invest 2012 Oct 14;30(8):615-21. Epub 2012 Aug 14.

Department of Medicine, Comprehensive Cancer Center-Central Nervous System Tumours Unit (CCC-CNS), Medical University of Vienna, Vienna, Austria.

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http://www.tandfonline.com/doi/full/10.3109/07357907.2012.70
Publisher Site
http://dx.doi.org/10.3109/07357907.2012.708071DOI Listing
October 2012

Neurocognitive and sociodemographic functioning of glioblastoma long-term survivors.

J Neurooncol 2012 Sep 29;109(2):331-9. Epub 2012 May 29.

Department of Medicine I, Medical University of Vienna, Austria Comprehensive Cancer Center - Central Nervous System Tumours Unit (CCC-CNS), Währinger Gürtel 18-20, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s11060-012-0897-1DOI Listing
September 2012

Strength of skeletal muscle and self-reported physical performance in Austrian glioblastoma-patients.

Wien Klin Wochenschr 2012 Jun 12;124(11-12):377-83. Epub 2012 Jun 12.

Department of Physical Medicine and Rehabilitation, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.

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http://dx.doi.org/10.1007/s00508-012-0186-1DOI Listing
June 2012

A management algorithm for cerebrospinal fluid leak associated with anterior skull base fractures: detailed clinical and radiological follow-up.

Neurosurg Rev 2012 Apr 27;35(2):227-37; discussion 237-8. Epub 2011 Sep 27.

Department of Neurosurgery, Medical University Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.

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http://link.springer.com/10.1007/s10143-011-0352-3
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http://dx.doi.org/10.1007/s10143-011-0352-3DOI Listing
April 2012

The veins of the nucleus dentatus: anatomical and radiological findings.

Neuroimage 2011 Jan 23;54(1):74-9. Epub 2010 Jul 23.

Centre for Anatomy and Cell Biology, Department of Systematic Anatomy, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/j.neuroimage.2010.07.045DOI Listing
January 2011

Residual nonfunctioning pituitary adenomas: prognostic value of MIB-1 labeling index for tumor progression.

J Neurosurg 2009 Sep;111(3):563-71

Institute of Neurology, Department of Neurosurgery, Medical University Vienna, Vienna, Austria.

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http://dx.doi.org/10.3171/2008.4.17517DOI Listing
September 2009