Georg Schett

Georg Schett

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Georg Schett

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Vascularised human skin equivalents as a novel in vitro model of skin fibrosis and platform for testing of antifibrotic drugs.

Ann Rheum Dis 2019 Dec 20;78(12):1686-1692. Epub 2019 Sep 20.

Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, Erlangen, Germany

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http://dx.doi.org/10.1136/annrheumdis-2019-216108DOI Listing
December 2019

Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions of disease states of gout.

Ann Rheum Dis 2019 Nov 9;78(11):1592-1600. Epub 2019 Sep 9.

Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.

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http://dx.doi.org/10.1136/annrheumdis-2019-215933DOI Listing
November 2019

Changes in mechanical loading affect arthritis-induced bone loss in mice.

Bone 2019 Nov 9:115149. Epub 2019 Nov 9.

Friedrich-Alexander-University Erlangen-Nuremberg (FAU), Department of Internal Medicine 3 -Rheumatology & Immunology, University Hospital Erlangen, Erlangen, Germany; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2019.115149DOI Listing
November 2019

Checkpoint inhibitor-induced eosinophilic fasciitis following high eosinophilia associated with complete response.

Rheumatology (Oxford) 2019 Oct;58(10):1875-1877

Department of Dermatology, Universitätsklinikum Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg (FAU), Erlangen, Germany.

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http://dx.doi.org/10.1093/rheumatology/kez164DOI Listing
October 2019

The Role of Dietary Fiber in Rheumatoid Arthritis Patients: A Feasibility Study.

Nutrients 2019 Oct 7;11(10). Epub 2019 Oct 7.

Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander University (FAU) Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany.

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http://dx.doi.org/10.3390/nu11102392DOI Listing
October 2019

Citrullination Licenses Calpain to Decondense Nuclei in Neutrophil Extracellular Trap Formation.

Front Immunol 2019 22;10:2481. Epub 2019 Oct 22.

Department of Medicine 1, Friedrich-Alexander-Universität Erlangen-Nürnberg, Deutsches Zentrum Immuntherapie, Kussmaul Campus for Medical Research and Translational Research Center, Erlangen, Germany.

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http://dx.doi.org/10.3389/fimmu.2019.02481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817590PMC
October 2019

Development of Joint Erosions in the Preclinical Phase of Rheumatoid Arthritis Depicted by Cinematic Rendering.

Arthritis Rheumatol 2019 Sep 22;71(9):1592. Epub 2019 Jul 22.

Friedrich Alexander University Erlangen-Nuremberg and Universitaetsklinikum Erlangen, Erlangen, Germany.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/art.41001
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http://dx.doi.org/10.1002/art.41001DOI Listing
September 2019

Comparison of the effects of tocilizumab monotherapy and adalimumab in combination with methotrexate on bone erosion repair in rheumatoid arthritis.

Ann Rheum Dis 2019 Sep 29;78(9):1186-1191. Epub 2019 May 29.

Department of Internal Medicine 3, Friedrich Alexander University Erlangen-Nurnberg and Universitaetsklinikum Erlangen, Erlangen, Germany

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http://dx.doi.org/10.1136/annrheumdis-2018-214894DOI Listing
September 2019

Acyltransferase skinny hedgehog regulates TGFβ-dependent fibroblast activation in SSc.

Ann Rheum Dis 2019 Sep 8;78(9):1269-1273. Epub 2019 Jun 8.

Department of Internal Medicine 3- Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Bayern, Germany

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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2019-21506
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http://dx.doi.org/10.1136/annrheumdis-2019-215066DOI Listing
September 2019

Extracellular DNA traps in inflammation, injury and healing.

Nat Rev Nephrol 2019 Sep 18;15(9):559-575. Epub 2019 Jun 18.

Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and University Hospital Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.1038/s41581-019-0163-2DOI Listing
September 2019

NOX2 mediates quiescent handling of dead cell remnants in phagocytes.

Redox Biol 2019 09 20;26:101279. Epub 2019 Jul 20.

Department of Medicine 3, Rheumatology and Immunology, Friedrich Alexander-University Erlangen-Nürnberg, Universitätsklinikum Erlangen, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2019.101279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669319PMC
September 2019

Next-generation imaging of the skeletal system and its blood supply.

Nat Rev Rheumatol 2019 Sep 8;15(9):533-549. Epub 2019 Aug 8.

Institute for Experimental Immunology and Imaging, University Hospital, University Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1038/s41584-019-0274-yDOI Listing
September 2019

Neutrophil Extracellular Traps Initiate Gallstone Formation.

Immunity 2019 Sep 15;51(3):443-450.e4. Epub 2019 Aug 15.

Friedrich Alexander University Erlangen-Nürnberg (FAU), Department of Internal Medicine 3 - Rheumatology and Immunology, Universitätsklinikum Erlangen, 90154 Erlangen, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613193031
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http://dx.doi.org/10.1016/j.immuni.2019.07.002DOI Listing
September 2019

Treatment with DNases rescues hidden neutrophil elastase from aggregated NETs.

J Leukoc Biol 2019 Sep 2. Epub 2019 Sep 2.

Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Department of Internal Medicine 3-Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlange, Germany.

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http://dx.doi.org/10.1002/JLB.3AB0918-370RDOI Listing
September 2019

Aggregated NETs Sequester and Detoxify Extracellular Histones.

Front Immunol 2019 11;10:2176. Epub 2019 Sep 11.

Department of Medicine 3 - Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.3389/fimmu.2019.02176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749074PMC
September 2019

T2 Mapping as a New Method for Quantitative Assessment of Cartilage Damage in RA.

J Rheumatol 2019 Aug 15. Epub 2019 Aug 15.

From the Department of Trauma and Orthopaedic Surgery, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany; Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany; Department of Radiology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany; UKE Athleticum, University Hospital of Hamburg-Eppendorf, Hamburg, Germany. Funding declaration: This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sector. Address correspondence to: Milena L. Pachowsky, MD Department of Trauma and Orthopaedic Surgery Universitätsklinikum Erlangen Krankenhausstr. 12 91052 Erlangen.

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http://dx.doi.org/10.3899/jrheum.180728DOI Listing
August 2019

Autoantibodies Recognizing Secondary NEcrotic Cells Promote Neutrophilic Phagocytosis and Identify Patients With Systemic Lupus Erythematosus.

Front Immunol 2018 7;9:989. Epub 2018 May 7.

Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.3389/fimmu.2018.00989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949357PMC
July 2019

Fra1 Controls Rheumatoid Factor Autoantibody Production by Bone Marrow Plasma Cells and the Development of Autoimmune Bone Loss.

J Bone Miner Res 2019 Jul 19;34(7):1352-1365. Epub 2019 Mar 19.

Department of Medicine 3, Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.1002/jbmr.3705DOI Listing
July 2019

Effect of disease-modifying anti-rheumatic drugs on bone structure and strength in psoriatic arthritis patients.

Arthritis Res Ther 2019 Jul 3;21(1):162. Epub 2019 Jul 3.

Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander University (FAU) Erlangen-Nürnberg and Universitätsklinikum Erlangen, Ulmenweg 18, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1186/s13075-019-1938-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607518PMC
July 2019

The gut-bone axis: how bacterial metabolites bridge the distance.

J Clin Invest 2019 07 15;129(8):3018-3028. Epub 2019 Jul 15.

Division of Endocrinology, Metabolism and Lipids, Department of Medicine, Emory University, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1172/JCI128521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668676PMC
July 2019

How Autoantibodies Regulate Osteoclast Induced Bone Loss in Rheumatoid Arthritis.

Front Immunol 2019 3;10:1483. Epub 2019 Jul 3.

Department of Internal Medicine 3, University of Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.3389/fimmu.2019.01483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619397PMC
July 2019

Disease interception with interleukin-17 inhibition in high-risk psoriasis patients with subclinical joint inflammation-data from the prospective IVEPSA study.

Arthritis Res Ther 2019 Jul 26;21(1):178. Epub 2019 Jul 26.

Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nurnberg (FAU) and Universitaetsklinikum Erlangen, Ulmenweg 18, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1186/s13075-019-1957-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659205PMC
July 2019

Dipeptidyl-peptidase-4 as a marker of activated fibroblasts and a potential target for the treatment of fibrosis in Systemic Sclerosis.

Arthritis Rheumatol 2019 Jul 26. Epub 2019 Jul 26.

Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-University (FAU) Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.1002/art.41058DOI Listing
July 2019

Effects of conventional uric acid lowering therapy on monosodium urate crystal deposits.

Arthritis Rheumatol 2019 Jul 28. Epub 2019 Jul 28.

Department of Internal Medicine 3, Friedrich-Alexander University Erlangen-Nuernberg and Universitätsklinikum Erlangen, Ulmenweg 18, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1002/art.41063DOI Listing
July 2019

In Vivo Models of Rheumatoid Arthritis.

Methods Mol Biol 2019 ;1914:269-280

Department of Medicine 3, Rheumatology and Immunology, University Hospital Erlangen, Erlangen, Germany.

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http://link.springer.com/10.1007/978-1-4939-8997-3_14
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http://dx.doi.org/10.1007/978-1-4939-8997-3_14DOI Listing
June 2019

Generation and Analysis of Human and Murine Osteoclasts.

Curr Protoc Immunol 2019 Jun 8;125(1):e74. Epub 2019 Apr 8.

Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Department of Internal Medicine 3-Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.1002/cpim.74DOI Listing
June 2019

Frontline Science: Aggregated neutrophil extracellular traps prevent inflammation on the neutrophil-rich ocular surface.

J Leukoc Biol 2019 Jun 12;105(6):1087-1098. Epub 2019 Apr 12.

Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.1002/JLB.HI0718-249RRDOI Listing
June 2019

Calcium pyrophosphate deposition disease induced inflammatory back pain.

Rheumatology (Oxford) 2019 Jun 17. Epub 2019 Jun 17.

Department of Internal Medicine 3, Rheumatology and Immunology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.

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https://academic.oup.com/rheumatology/advance-article/doi/10
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http://dx.doi.org/10.1093/rheumatology/kez225DOI Listing
June 2019

Cost-effective Tapering Algorithm in Patients with Rheumatoid Arthritis: Combination of Multibiomarker Disease Activity Score and Autoantibody Status.

J Rheumatol 2019 May 1;46(5):460-466. Epub 2018 Dec 1.

From the Friedrich-Alexander-University Erlangen-Nuremberg (FAU), Department of Internal Medicine 3 - Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany; St. Vincent Hospital, Vinforce Study Group, Medical University of Vienna, Vienna, Austria; Institutio de Rheumatologia, São Paolo, Brazil; University of Würzburg, Internal Medicine 2, Würzburg; University Medical Center Freiburg, Rheumatology and Clinical Immunology, Freiburg; Rheumatology Clinical Practice Erlangen, Erlangen; Rheumatology Practice and Department of Internal Medicine 2, Clinic Burghausen, Burghausen; Asklepios Medical Center, Department of Rheumatology and clinical Immunology, Bad Abbach; Rheumatology Practice Bamberg, Bamberg; Rheumatology Practice Bayreuth, Bayreuth; University of Heidelberg, Medicine 5, Heidelberg; Rheumatology Practice Nuremberg, Nuremberg; Schlosspark Klinik, Internal Medicine/Rheumatology, Berlin; University of Tübingen, Centre for Interdisciplinary Clinical Immunology, Tübingen; Praxiszentrum St. Bonifatius, Munich, Germany.

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.180028
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http://dx.doi.org/10.3899/jrheum.180028DOI Listing
May 2019

Long-term experience with apremilast in patients with psoriatic arthritis: 5-year results from a PALACE 1-3 pooled analysis.

Arthritis Res Ther 2019 May 10;21(1):118. Epub 2019 May 10.

Rheumatology Clinical Research Division, Swedish Medical Center/Providence St. Joseph Health and University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1186/s13075-019-1901-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509758PMC
May 2019

Response to: 'Idiopathic inflammatory myopathies and antisynthetase syndrome: contribution of antisynthetase antibodies to improve current classification criteria' by Greco .

Ann Rheum Dis 2019 Apr 17. Epub 2019 Apr 17.

Department of Internal Medicine 3, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1136/annrheumdis-2019-215484DOI Listing
April 2019

What Are the Peripheral Blood Determinants for Increased Osteoclast Formation in the Various Inflammatory Diseases Associated With Bone Loss?

Front Immunol 2019 19;10:505. Epub 2019 Mar 19.

Gerontology and Bone Metabolic Diseases Division, Department of Medical Science, University of Turin, Turin, Italy.

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http://dx.doi.org/10.3389/fimmu.2019.00505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434996PMC
March 2019

Effects of ustekinumab versus tumor necrosis factor inhibition on enthesitis: Results from the enthesial clearance in psoriatic arthritis (ECLIPSA) study.

Semin Arthritis Rheum 2019 02 13;48(4):632-637. Epub 2018 Jun 13.

Department of Internal Medicine and Institute for Clinical Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2018.05.011DOI Listing
February 2019

I would never take preventive medication! Perspectives and information needs of people who underwent predictive tests for rheumatoid arthritis.

Arthritis Care Res (Hoboken) 2019 Feb 2. Epub 2019 Feb 2.

Section for Outcomes Research, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/acr.23841DOI Listing
February 2019

Checkpoint Inhibitors.

Dtsch Arztebl Int 2019 Feb;116(8):119-126

Department of Dermatology, University Hospital Erlangen-Nürnberg; Department of Internal Medicine II, University Hospital, Ludwig-Maximilians-University (LMU )Munich; Department of Medicine 3, University Hospital Erlangen-Nürnberg; Department of Medicine 1, University Hospital Erlangen-Nürnberg; Clinic for Dermatology, Essen University Hospital, University of Duisburg-Essen.

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http://dx.doi.org/10.3238/arztebl.2019.0119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454802PMC
February 2019

Anti-inflammatory and immune-regulatory cytokines in rheumatoid arthritis.

Nat Rev Rheumatol 2019 Jan;15(1):9-17

Department of Internal Medicine 3, Friedrich Alexander University Erlangen-Nuremberg and Universitatsklinikum Erlangen, Erlangen, Germany.

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http://www.nature.com/articles/s41584-018-0109-2
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http://dx.doi.org/10.1038/s41584-018-0109-2DOI Listing
January 2019

Response to: 'Is the PET/CT first choice for differential diagnosis of FUO/IUO?' by Armagan .

Ann Rheum Dis 2018 11 2;77(11):e83. Epub 2018 Feb 2.

Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nuremberg, Universitatsklinikum Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.1136/annrheumdis-2017-212785DOI Listing
November 2018

Fra-2 Expression in Osteoblasts Regulates Systemic Inflammation and Lung Injury through Osteopontin.

Mol Cell Biol 2018 11 29;38(22). Epub 2018 Oct 29.

Friedrich-Alexander University Erlangen-Nürnberg, Department of Internal Medicine 3 Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany

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http://mcb.asm.org/lookup/doi/10.1128/MCB.00022-18
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http://dx.doi.org/10.1128/MCB.00022-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206458PMC
November 2018

Effects of the IL-23-IL-17 pathway on bone in spondyloarthritis.

Nat Rev Rheumatol 2018 11;14(11):631-640

Department of Internal Medicine 3, Friedrich Alexander University Erlangen-Nuremberg and Universitatsklinikum Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.1038/s41584-018-0091-8DOI Listing
November 2018

Remission in psoriatic arthritis-where are we now?

Rheumatology (Oxford) 2018 08;57(8):1321-1331

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Leeds, UK.

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http://dx.doi.org/10.1093/rheumatology/kex344DOI Listing
August 2018

Response to: the value of 18(F)-FDG-PET/CT in identifying the cause of fever of unknown origin (FUO) and inflammation of unknown origin (IUO): data from a prospective study.

Ann Rheum Dis 2018 08 16;77(8):e53. Epub 2017 Nov 16.

Department of Internal Medicine 3 and Institute for Clinical Immunology, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1136/annrheumdis-2017-212520DOI Listing
August 2018

A model of chronic enthesitis and new bone formation characterized by multimodal imaging.

Dis Model Mech 2018 08 30;11(9). Epub 2018 Aug 30.

Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, 91054, Erlangen, Germany

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http://dmm.biologists.org/lookup/doi/10.1242/dmm.034041
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http://dx.doi.org/10.1242/dmm.034041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176995PMC
August 2018

Resolution of chronic inflammatory disease: universal and tissue-specific concepts.

Nat Commun 2018 08 15;9(1):3261. Epub 2018 Aug 15.

Department of Internal Medicine 1, Friedrich-Alexander University Erlangen-Nürnberg and Universitatsklinikum Erlangen, 91054, Erlangen, Germany.

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http://www.nature.com/articles/s41467-018-05800-6
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http://dx.doi.org/10.1038/s41467-018-05800-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093916PMC
August 2018

Cortical bone loss is an early feature of nonradiographic axial spondyloarthritis.

Arthritis Res Ther 2018 08 30;20(1):202. Epub 2018 Aug 30.

Department of Internal Medicine 3, Friedrich Alexander University Erlangen-Nurnberg and Universitätsklinikum Erlangen, Ulmenweg 18, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1186/s13075-018-1620-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117894PMC
August 2018

Simultaneous quantification of bone erosions and enthesiophytes in the joints of patients with psoriasis or psoriatic arthritis - effects of age and disease duration.

Arthritis Res Ther 2018 08 31;20(1):203. Epub 2018 Aug 31.

Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Department of Internal Medicine 3 - Rheumatology and Immunology, Universitätsklinikum Erlangen, Ulmenweg 18, D-91054, Erlangen, Germany.

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https://arthritis-research.biomedcentral.com/articles/10.118
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http://dx.doi.org/10.1186/s13075-018-1691-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117875PMC
August 2018

Biomechanical properties of bone are impaired in patients with ACPA-positive rheumatoid arthritis and associated with the occurrence of fractures.

Ann Rheum Dis 2018 07 23;77(7):973-980. Epub 2018 Feb 23.

Friedrich Alexander University Erlangen-Nürnberg, Department of Internal Medicine 3, Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.1136/annrheumdis-2017-212404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029639PMC
July 2018

Low amounts of bisecting glycans characterize cerebrospinal fluid-borne IgG.

J Neuroimmunol 2018 07 16;320:19-24. Epub 2018 Apr 16.

Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Department of Internal Medicine 3, Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2018.04.010DOI Listing
July 2018

Group 2 Innate Lymphoid Cells Attenuate Inflammatory Arthritis and Protect from Bone Destruction in Mice.

Cell Rep 2018 07;24(1):169-180

Department of Internal Medicine 3, Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.06.005DOI Listing
July 2018

EGFR controls bone development by negatively regulating mTOR-signaling during osteoblast differentiation.

Cell Death Differ 2018 06 14;25(6):1094-1106. Epub 2018 Feb 14.

Department of Internal Medicine I, Institute of Cancer Research, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1038/s41418-017-0054-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988706PMC
June 2018

Poly(ADP-ribose) polymerase-1 regulates fibroblast activation in systemic sclerosis.

Ann Rheum Dis 2018 05 3;77(5):744-751. Epub 2018 Feb 3.

Department of Internal Medicine 3 for Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), University Hospital of Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.1136/annrheumdis-2017-212265DOI Listing
May 2018

Eosinophils are not essential for maintenance of murine plasma cells in the bone marrow.

Eur J Immunol 2018 05 5;48(5):822-828. Epub 2018 Mar 5.

Department of Internal Medicine III and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1002/eji.201747227DOI Listing
May 2018

Osteoimmunology.

Calcif Tissue Int 2018 05 13;102(5):501-502. Epub 2018 Apr 13.

Department of Internal Medicine 3, Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nuremberg and Universitatsklinikum Erlangen, Ulmenweg 18, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1007/s00223-018-0421-5DOI Listing
May 2018

Upper zone of growth plate and cartilage matrix associated protein protects cartilage during inflammatory arthritis.

Arthritis Res Ther 2018 05 2;20(1):88. Epub 2018 May 2.

Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Universitätsklinikum Erlangen, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1186/s13075-018-1583-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932879PMC
May 2018

Methods for segmentation of rheumatoid arthritis bone erosions in high-resolution peripheral quantitative computed tomography (HR-pQCT).

Semin Arthritis Rheum 2018 04 23;47(5):611-618. Epub 2017 Sep 23.

Institute of Medical Physics (IMP), Friedrich-Alexander-University Erlangen-Nüremberg (FAU), Henkestrasse 91, Erlangen 91052, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2017.09.011DOI Listing
April 2018

Protein kinases G are essential downstream mediators of the antifibrotic effects of sGC stimulators.

Ann Rheum Dis 2018 03 8;77(3):459. Epub 2018 Jan 8.

Department of Internal Medicine III - Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Universitätsklinikum Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.1136/annrheumdis-2017-212489DOI Listing
March 2018

The B cell response to citrullinated antigens in the development of rheumatoid arthritis.

Nat Rev Rheumatol 2018 03 8;14(3):157-169. Epub 2018 Feb 8.

Department of Rheumatology, Leiden University Medical Center, PO Box 9600, 2300RC Leiden, The Netherlands.

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http://www.nature.com/doifinder/10.1038/nrrheum.2018.10
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http://dx.doi.org/10.1038/nrrheum.2018.10DOI Listing
March 2018

Unilateral plantar erythema nodosum in sarcoidosis.

Arthritis Rheumatol 2018 02 5;70(2):297. Epub 2018 Jan 5.

Friedrich-Alexander University Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.1002/art.40341DOI Listing
February 2018

Cutting Edge: Homeostasis of Innate Lymphoid Cells Is Imbalanced in Psoriatic Arthritis.

J Immunol 2018 02 12;200(4):1249-1254. Epub 2018 Jan 12.

Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany; and

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http://dx.doi.org/10.4049/jimmunol.1700596DOI Listing
February 2018

Abatacept blocks anti-citrullinated protein antibody and rheumatoid factor mediated cytokine production in human macrophages in IDO-dependent manner.

Arthritis Res Ther 2018 02 7;20(1):24. Epub 2018 Feb 7.

Department of Internal Medicine 3 and Institute for Clinical Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum, Ulmenweg 18, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1186/s13075-018-1527-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803926PMC
February 2018

Physiological effects of modulating the interleukin-6 axis.

Authors:
Georg Schett

Rheumatology (Oxford) 2018 02;57(suppl_2):ii43-ii50

Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.1093/rheumatology/kex513DOI Listing
February 2018

The value of F-FDG-PET/CT in identifying the cause of fever of unknown origin (FUO) and inflammation of unknown origin (IUO): data from a prospective study.

Ann Rheum Dis 2018 Jan 19;77(1):70-77. Epub 2017 Sep 19.

Department of Internal Medicine 3, Institute for Clinical Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum, Erlangen, Germany.

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http://dx.doi.org/10.1136/annrheumdis-2017-211687DOI Listing
January 2018

The histone demethylase Jumonji domain-containing protein 3 (JMJD3) regulates fibroblast activation in systemic sclerosis.

Ann Rheum Dis 2018 Jan 25;77(1):150-158. Epub 2017 Oct 25.

Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, Erlangen, Bayern, Germany.

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http://dx.doi.org/10.1136/annrheumdis-2017-211501DOI Listing
January 2018

Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss.

Nat Commun 2018 01 4;9(1):55. Epub 2018 Jan 4.

Department of Internal Medicine 3, Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1038/s41467-017-02490-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754356PMC
January 2018

Hypoxia-inducible factor-1α is a critical transcription factor for IL-10-producing B cells in autoimmune disease.

Nat Commun 2018 01 17;9(1):251. Epub 2018 Jan 17.

Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, 91054, Erlangen, Germany.

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http://www.nature.com/articles/s41467-017-02683-x
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http://dx.doi.org/10.1038/s41467-017-02683-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772476PMC
January 2018

Interleukin-36 receptor mediates the crosstalk between plasma cells and synovial fibroblasts.

Eur J Immunol 2017 12 22;47(12):2101-2112. Epub 2017 Sep 22.

Department of Internal Medicine 3 - Rheumatology and Immunology, Universitätsklinikum Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Germany.

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http://dx.doi.org/10.1002/eji.201646788DOI Listing
December 2017

Enthesitis: from pathophysiology to treatment.

Nat Rev Rheumatol 2017 Nov;13(12):731-741

Section of Musculoskeletal Diseases, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and Chapel Allerton Hospital, Chapeltown Road, Leeds, West Yorkshire LS7 4SA, UK.

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http://dx.doi.org/10.1038/nrrheum.2017.188DOI Listing
November 2017

Long-term Combination Therapy with Anti-TNF plus Vedolizumab Induces and Maintains Remission in Therapy-refractory Ulcerative Colitis.

Am J Gastroenterol 2017 10;112(10):1621-1623

Department of Medicine 1, Friedrich-Alexander-Universität Erlangen-Nìrnberg, Erlangen, Germany.

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http://dx.doi.org/10.1038/ajg.2017.242DOI Listing
October 2017

Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis.

Nat Commun 2017 10 24;8(1):1130. Epub 2017 Oct 24.

Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, Erlangen, 91054, Germany.

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http://dx.doi.org/10.1038/s41467-017-01236-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654983PMC
October 2017

The role of ACPAs in at-risk individuals: Early targeting of the bone and joints.

Authors:
Georg Schett

Best Pract Res Clin Rheumatol 2017 02 6;31(1):53-58. Epub 2017 Nov 6.

Department of Internal Medicine 3 and Institute for Clinical Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.berh.2017.09.015DOI Listing
February 2017