Georg Krupitza

Georg Krupitza

UNVERIFIED PROFILE

Are you Georg Krupitza?   Register this Author

Register author
Georg Krupitza

Georg Krupitza

Publications by authors named "Georg Krupitza"

Are you Georg Krupitza?   Register this Author

90Publications

2523Reads

10Profile Views

Impact of Weight Loss Strategies on Obesity-Induced DNA Damage.

Mol Nutr Food Res 2019 09 14;63(17):e1900045. Epub 2019 Jun 14.

Department of Internal Medicine I, Institute of Cancer Research, Medical University of Vienna, Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mnfr.201900045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771950PMC
September 2019

High impact of miRNA-4521 on FOXM1 expression in medulloblastoma.

Cell Death Dis 2019 Sep 20;10(10):696. Epub 2019 Sep 20.

Department of Pediatrics and Adolescent Medicine, Molecular Neuro-Oncology, Medical University of Vienna, Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41419-019-1926-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754377PMC
September 2019

Chemical Composition of and the Effects on Tumor Invasiveness .

Front Pharmacol 2018 3;9:304. Epub 2018 Apr 3.

Department of Pharmacognosy, Faculty of Life Sciences, University of Vienna, Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fphar.2018.00304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891616PMC
April 2018

Thiosemicarbazone derivatives, thiazolyl hydrazones, effectively inhibit leukemic tumor cell growth: Down-regulation of ribonucleotide reductase activity and synergism with arabinofuranosylcytosine.

Food Chem Toxicol 2017 Oct 14;108(Pt A):53-62. Epub 2017 Jul 14.

Department of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria; Department of Pathology, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fct.2017.07.029DOI Listing
October 2017

Isolation of eudesmanes from Pluchea odorata and evaluation of their effects on cancer cell growth and tumor invasiveness in vitro.

Phytochemistry 2017 Sep 26;141:37-47. Epub 2017 May 26.

Department of Pharmacognosy, University of Vienna, Althanstraße 14, 1090 Vienna, Austria. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phytochem.2017.05.009DOI Listing
September 2017

Comparison of cancer cells in 2D vs 3D culture reveals differences in AKT-mTOR-S6K signaling and drug responses.

J Cell Sci 2017 01 23;130(1):203-218. Epub 2016 Sep 23.

Institute of Medical Genetics, Medical University of Vienna, Währinger Straße 10, Vienna A-1090, Austria

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jcs.188102DOI Listing
January 2017

The Tradescantia micronucleus assay is a highly sensitive tool for the detection of low levels of radioactivity in environmental samples.

Environ Pollut 2016 Dec 7;219:1044-1048. Epub 2016 Sep 7.

Institute of Cancer Research, Department of Internal Medicine I, Borschkegasse 8a, Vienna 1090, Austria. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.envpol.2016.09.004DOI Listing
December 2016

The microRNA-200 family: still much to discover.

Biomol Concepts 2016 Dec;7(5-6):311-319

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1515/bmc-2016-0020DOI Listing
December 2016

Cancer cell-derived 12(S)-HETE signals via 12-HETE receptor, RHO, ROCK and MLC2 to induce lymph endothelial barrier breaching.

Br J Cancer 2016 07 30;115(3):364-70. Epub 2016 Jun 30.

Clinical Institute of Pathology, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/bjc.2016.201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973159PMC
July 2016

Increased complexity in carcinomas: Analyzing and modeling the interaction of human cancer cells with their microenvironment.

Semin Cancer Biol 2015 Dec 28;35:107-24. Epub 2015 Aug 28.

Institute of Medical Genetics, Medical University of Vienna, Währinger Straße 10, A-1090 Vienna, Austria. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.semcancer.2015.08.007DOI Listing
December 2015

Loss of miR-200 family in 5-fluorouracil resistant colon cancer drives lymphendothelial invasiveness in vitro.

Hum Mol Genet 2015 Jul 1;24(13):3689-98. Epub 2015 Apr 1.

Department of Medicine I, Comprehensive Cancer Center of the Medical University of Vienna, 1090 Vienna, Austria,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddv113DOI Listing
July 2015

The effect of organic anion-transporting polypeptides 1B1, 1B3 and 2B1 on the antitumor activity of flavopiridol in breast cancer cells.

Int J Oncol 2015 Jan 24;46(1):324-32. Epub 2014 Oct 24.

Department of Clinical Pharmacy and Diagnostics, University of Vienna, Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/ijo.2014.2731DOI Listing
January 2015

Fibroblast growth factor receptor 4: a putative key driver for the aggressive phenotype of hepatocellular carcinoma.

Carcinogenesis 2014 Oct 16;35(10):2331-8. Epub 2014 Jul 16.

Department of Medicine I, Division: Institute of Cancer Research, Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna, Austria and Institute of Clinical Pathology, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria

View Article

Download full-text PDF

Source
http://carcin.oxfordjournals.org/content/35/10/2331.full.pdf
Web Search
http://www.carcin.oxfordjournals.org/cgi/doi/10.1093/carcin/
Publisher Site
http://dx.doi.org/10.1093/carcin/bgu151DOI Listing
October 2014

Cytotoxic constituents from Lobaria scrobiculata and a comparison of two bioassays for their evaluation.

J Nat Prod 2014 Apr 11;77(4):1069-73. Epub 2014 Apr 11.

Department of Pharmacognosy, Faculty of Life Sciences, University of Vienna , Althanstraße 14, A-1090 Vienna, Austria.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/np4008574
Publisher Site
http://dx.doi.org/10.1021/np4008574DOI Listing
April 2014

In vitro cell migration and invasion assays.

Mutat Res 2013 Jan-Mar;752(1):10-24. Epub 2012 Aug 23.

Institute of Medical Genetics, Medical University of Vienna, A-1090 Vienna, Währinger Strasse 10, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mrrev.2012.08.001DOI Listing
April 2013

Induction of nuclear anomalies in exfoliated buccal cells of coca chewers: results of a field study.

Arch Toxicol 2013 Mar 6;87(3):529-34. Epub 2012 Nov 6.

Department of Internal Medicine 1, Institute of Cancer Research, Medical University of Vienna, Borschkegasse 8A, 1090, Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00204-012-0969-1DOI Listing
March 2013

Effects on inflammatory responses by the sphingoid base 4,8-sphingadienine.

Int J Mol Med 2012 Sep 15;30(3):703-7. Epub 2012 Jun 15.

Department of Pharmacognosy, University of Vienna, A-1090 Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/ijmm.2012.1035DOI Listing
September 2012

Characterization of glucocerebrosides and the active metabolite 4,8-sphingadienine from Arisaema amurense and Pinellia ternata by NMR and CD spectroscopy and ESI-MS/CID-MS.

J Agric Food Chem 2012 Jul 13;60(29):7204-10. Epub 2012 Jul 13.

Department of Pharmacognosy, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jf302085uDOI Listing
July 2012

The major vault protein mediates resistance to epidermal growth factor receptor inhibition in human hepatoma cells.

Cancer Lett 2012 Jun 17;319(2):164-172. Epub 2012 Jan 17.

Institute of Cancer Research, Department of Medicine I, Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna, Austria. Electronic address:

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S030438351200027
Publisher Site
http://dx.doi.org/10.1016/j.canlet.2012.01.002DOI Listing
June 2012

Combination effects of digalloylresveratrol with arabinofuranosylcytosine and difluorodeoxycytidine in human leukemia and pancreatic cancer cells.

Nucleosides Nucleotides Nucleic Acids 2011 Dec;30(12):1190-6

Department of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, General Hospital of Vienna, Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15257770.2011.596497DOI Listing
December 2011

Initial steps of metastasis: cell invasion and endothelial transmigration.

Mutat Res 2011 Jul-Oct;728(1-2):23-34. Epub 2011 May 12.

Department of Medicine I, Medical University of Vienna, Borschkegasse 8a, 1090 Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mrrev.2011.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028085PMC
October 2011

Metabolomic analysis of resveratrol-induced effects in the human breast cancer cell lines MCF-7 and MDA-MB-231.

OMICS 2011 Jan-Feb;15(1-2):9-14. Epub 2011 Jan 17.

Department of Clinical Pharmacy and Diagnostics, University of Vienna, Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/omi.2010.0114DOI Listing
May 2011

Ferruginenes A-C from Rhododendron ferrugineum and their cytotoxic evaluation.

J Nat Prod 2011 Apr 28;74(4):712-7. Epub 2011 Mar 28.

Center of Excellence for Innovation in Chemistry (PERCH-CIC) and Department of Chemistry, Faculty of Science, Mahasarakham University, Maha Sarakham, 44150 Thailand.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/np100778kDOI Listing
April 2011

A novel N-hydroxy-N'-aminoguanidine derivative inhibits ribonucleotide reductase activity: Effects in human HL-60 promyelocytic leukemia cells and synergism with arabinofuranosylcytosine (Ara-C).

Biochem Pharmacol 2011 Jan 16;81(1):50-9. Epub 2010 Sep 16.

Department of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, General Hospital of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bcp.2010.09.006DOI Listing
January 2011

Antiproliferative effects of some novel synthetic solanidine analogs on HL-60 human leukemia cells in vitro.

Steroids 2011 Jan 23;76(1-2):156-62. Epub 2010 Oct 23.

Department of Pharmacodynamics and Biopharmacy, University of Szeged, H-6720 Szeged, Eötvös u. 6, Hungary.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.steroids.2010.10.006DOI Listing
January 2011

Antitumor effects of KITC, a new resveratrol derivative, in AsPC-1 and BxPC-3 human pancreatic carcinoma cells.

Invest New Drugs 2009 Oct 8;27(5):393-401. Epub 2008 Oct 8.

Clinical Institute of Medical and Chemical Laboratory Diagnostics, General Hospital of Vienna, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10637-008-9183-7
Publisher Site
http://dx.doi.org/10.1007/s10637-008-9183-7DOI Listing
October 2009

Digalloylresveratrol, a new phenolic acid derivative induces apoptosis and cell cycle arrest in human HT-29 colon cancer cells.

Cancer Lett 2009 Feb 25;274(2):299-304. Epub 2008 Oct 25.

Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, General Hospital of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2008.09.020DOI Listing
February 2009

Altered expression of organic anion transporter polypeptide (OATP) genes in human breast carcinoma.

Cancer Biol Ther 2008 Sep 13;7(9):1450-5. Epub 2008 Sep 13.

Department of Clinical Pharmacy and Diagnostics, University of Vienna, Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cbt.7.9.6282DOI Listing
September 2008

Synergistic effects of deuterium oxide and gemcitabine in human pancreatic cancer cell lines.

Cancer Lett 2008 Feb 26;259(2):231-9. Epub 2007 Nov 26.

Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, General Hospital of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2007.10.010DOI Listing
February 2008

Oncogenic c-H-ras deregulates survivin expression: an improvement for survival.

FEBS Lett 2007 Oct 21;581(25):4921-6. Epub 2007 Sep 21.

Clinics of Internal Medicine I, Division Institute of Cancer Research, Medical University of Vienna, Borschkegasse 8a, 1090 Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.febslet.2007.09.023DOI Listing
October 2007

Avemar, a nontoxic fermented wheat germ extract, induces apoptosis and inhibits ribonucleotide reductase in human HL-60 promyelocytic leukemia cells.

Cancer Lett 2007 Jun 29;250(2):323-8. Epub 2006 Nov 29.

Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, General Hospital of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2006.10.018DOI Listing
June 2007

Gallic acid inhibits ribonucleotide reductase and cyclooxygenases in human HL-60 promyelocytic leukemia cells.

Cancer Lett 2007 Jan 20;245(1-2):156-62. Epub 2006 Feb 20.

Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, General Hospital of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03043835060002
Publisher Site
http://dx.doi.org/10.1016/j.canlet.2006.01.001DOI Listing
January 2007

Cytotoxic and biochemical effects of 3,3',4,4',5,5'-hexahydroxystilbene, a novel resveratrol analog in HL-60 human promyelocytic leukemia cells.

Exp Hematol 2006 Oct;34(10):1377-84

Clinical Institute of Medical and Chemical Laboratory Diagnostics, General Hospital of Vienna, Medical University of Vienna, Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exphem.2006.05.018DOI Listing
October 2006

Immunologic and biochemical effects of the fermented wheat germ extract Avemar.

Exp Biol Med (Maywood) 2005 Feb;230(2):144-9

Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, General Hospital of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/153537020523000209DOI Listing
February 2005

Truncated ALK derived from chromosomal translocation t(2;5)(p23;q35) binds to the SH3 domain of p85-PI3K.

Mutat Res 2005 Feb;570(1):9-15

Institute of Clinical Pathology, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mrfmmm.2004.09.011DOI Listing
February 2005

The evolution of cell death programs as prerequisites of multicellularity.

Mutat Res 2003 Jun;543(3):235-49

Institute of Clinical Pathology, University of Vienna, Währinger Gürtel 18-20, A-1090 Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s1383-5742(02)00110-2DOI Listing
June 2003

Trimidox, an inhibitor of ribonucleotide reductase, synergistically enhances the inhibition of colony formation by Ara-C in HL-60 human promyelocytic leukemia cells.

Biochem Pharmacol 2002 Aug;64(3):481-5

Clinical Institute for Medical and Chemical Laboratory Diagnostics, General Hospital of Vienna, Medical School, University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0006-2952(02)01186-3DOI Listing
August 2002

Derivation of nephrogenic adenomas from renal tubular cells in kidney-transplant recipients.

N Engl J Med 2002 Aug;347(9):653-9

Department of Clinical Pathology and Center of Excellence in Clinical and Experimental Oncology, University of Vienna General Hospital, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa013413DOI Listing
August 2002

Potential mechanisms of benzamide riboside mediated cell death.

Curr Med Chem 2002 Apr;9(7):765-71

Institute of Clinical Pathology, University of Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/0929867024606849DOI Listing
April 2002