Publications by authors named "Georg Hansmann"

92Publications

Paediatric/congenital cardiology physician scientists-An endangered species.

Eur J Clin Invest 2020 Jul 31:e13367. Epub 2020 Jul 31.

Department of Cardiology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1111/eci.13367DOI Listing
July 2020

Pulmonary hypertension in bronchopulmonary dysplasia.

Pediatr Res 2020 Jun 10. Epub 2020 Jun 10.

Division of Pediatric Cardiology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1038/s41390-020-0993-4DOI Listing
June 2020

Pulmonary Hypertension in Adults with Congenital Heart Disease: Real-World Data from the International COMPERA-CHD Registry.

J Clin Med 2020 05 13;9(5). Epub 2020 May 13.

Universitätsklinik Köln- Herzzentrum, Klinik III für Innere Medizin, 50937 Köln, Germany.

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http://dx.doi.org/10.3390/jcm9051456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290703PMC
May 2020

Left Ventricular Geometry and Near-Simultaneous Invasive Hemodynamics in Pediatric Pulmonary Hypertension.

Circ Cardiovasc Imaging 2020 May 15;13(5):e010787. Epub 2020 May 15.

European Pediatric Pulmonary Vascular Disease Network, Berlin, Germany (M.K., G.H.).

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http://dx.doi.org/10.1161/CIRCIMAGING.120.010787DOI Listing
May 2020

Selexipag for the treatment of children with pulmonary arterial hypertension: First multicenter experience in drug safety and efficacy.

J Heart Lung Transplant 2020 Jul 7;39(7):695-706. Epub 2020 Apr 7.

Division of Pediatric Cardiology, Department of Pediatrics, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1016/j.healun.2020.03.029DOI Listing
July 2020

A novel echocardiographic approach indicates disease severity in pediatric pulmonary hypertension.

Pediatr Int 2020 05 17;62(5):637-639. Epub 2020 Apr 17.

Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1111/ped.14163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318688PMC
May 2020

Trans-right ventricle and transpulmonary metabolite gradients in human pulmonary arterial hypertension.

Heart 2020 Sep 20;106(17):1332-1341. Epub 2020 Feb 20.

Department of Pediatric Cardiology and Critical care, Hannover Medical School, Hannover, Germany

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http://dx.doi.org/10.1136/heartjnl-2019-315900DOI Listing
September 2020

Trans-Right-Ventricle and Transpulmonary MicroRNA Gradients in Human Pulmonary Arterial Hypertension.

Pediatr Crit Care Med 2020 04;21(4):340-349

All authors: Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1097/PCC.0000000000002207DOI Listing
April 2020

Activation of the Metabolic Master Regulator PPARγ: A Potential PIOneering Therapy for Pulmonary Arterial Hypertension.

Am J Respir Cell Mol Biol 2020 02;62(2):143-156

Pittsburgh Heart, Lung, Blood, and Vascular Medicine Institute, and.

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http://dx.doi.org/10.1165/rcmb.2019-0226PSDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993553PMC
February 2020

Hypoxia drives cardiac miRNAs and inflammation in the right and left ventricle.

J Mol Med (Berl) 2019 10 23;97(10):1427-1438. Epub 2019 Jul 23.

Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.

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http://dx.doi.org/10.1007/s00109-019-01817-6DOI Listing
October 2019

The PPARγ agonist pioglitazone prevents TGF-β induced renal fibrosis by repressing EGR-1 and STAT3.

BMC Nephrol 2019 07 5;20(1):245. Epub 2019 Jul 5.

Department of Pathophysiology, Semmelweis University, Nagyvárad tér 4, Budapest, H-1089, Hungary.

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http://dx.doi.org/10.1186/s12882-019-1431-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610924PMC
July 2019

Chronic TGF-β1 Signaling in Pulmonary Arterial Hypertension Induces Sustained Canonical Smad3 Pathways in Vascular Smooth Muscle Cells.

Am J Respir Cell Mol Biol 2019 07;61(1):121-123

1 Department of Pediatric Cardiology and Critical Care Hannover Medical School Hannover, Germany and.

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http://dx.doi.org/10.1165/rcmb.2018-0275LEDOI Listing
July 2019

LRP1 Deficiency in Vascular SMC Leads to Pulmonary Arterial Hypertension That Is Reversed by PPARγ Activation.

Circ Res 2019 06 26;124(12):1778-1785. Epub 2019 Apr 26.

From the Department of Pediatric Cardiology and Critical Care (L.C., G.H.), Hannover Medical School, Germany.

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http://dx.doi.org/10.1161/CIRCRESAHA.119.315088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554044PMC
June 2019

Sympathetic nervous system controls resolution of inflammation via regulation of repulsive guidance molecule A.

Nat Commun 2019 02 7;10(1):633. Epub 2019 Feb 7.

Department of Anesthesiology and Intensive Care Medicine, Molecular Intensive Care Medicine, University Hospital Tübingen, Eberhard-Karls University, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany.

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http://dx.doi.org/10.1038/s41467-019-08328-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367413PMC
February 2019

A pediatric perspective on the TAPSE/PASP ratio in pulmonary arterial hypertension.

Int J Cardiol 2019 03;278:242

Departments of Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1016/j.ijcard.2018.11.092DOI Listing
March 2019

Tricuspid annular plane systolic excursion (TAPSE) in pediatric pulmonary hypertension: Integrating right ventricular ejection efficiency (RVEe) into advanced multi-parametric imaging.

Int J Cardiol 2019 Jan 3;274:296-298. Epub 2018 Jul 3.

Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Germany.

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http://dx.doi.org/10.1016/j.ijcard.2018.07.013DOI Listing
January 2019

Pathobiology, pathology and genetics of pulmonary hypertension: Update from the Cologne Consensus Conference 2018.

Int J Cardiol 2018 Dec 20;272S:4-10. Epub 2018 Sep 20.

Excellence Cluster Cardiopulmonary System, University of Giessen Lung Center, German Center for Lung Research (DZL), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany.

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http://dx.doi.org/10.1016/j.ijcard.2018.09.070DOI Listing
December 2018

Should we use the oral selective IP receptor agonist selexipag off-label in children with pulmonary arterial hypertension?

Pulm Circ 2018 Jul-Sep;8(3):2045894018793580

2 Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Germany.

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http://dx.doi.org/10.1177/2045894018793580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161208PMC
September 2018

Inhibition of neogenin fosters resolution of inflammation and tissue regeneration.

J Clin Invest 2018 10 17;128(10):4711-4726. Epub 2018 Sep 17.

Department of Anesthesiology and Intensive Care Medicine, Molecular Intensive Care Medicine, University Hospital Tübingen, Eberhard-Karls University Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1172/JCI96259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159953PMC
October 2018

Echocardiographic estimation of elevated right ventricular afterload in preterm infants at risk for pulmonary hypertension: next steps.

J Pediatr 2018 11 23;202:335-336. Epub 2018 Aug 23.

Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover, Germany; On behalf of the European Pediatric Pulmonary Vascular Disease Network.

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http://dx.doi.org/10.1016/j.jpeds.2018.07.054DOI Listing
November 2018

Reply to "Diagnostic and prognostic value of echocardiography in pulmonary arterial hypertension".

Clin Cardiol 2018 09 21;41(9):1152-1153. Epub 2018 Aug 21.

Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1002/clc.23038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489919PMC
September 2018

Different indications for transcatheter and surgical patent ductus arteriosus closure in preterm infants less than 2kg.

Int J Cardiol 2018 09;266:83

Department of Pediatric Cardiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1016/j.ijcard.2017.11.029DOI Listing
September 2018

The right ventricular outflow tract in pediatric pulmonary hypertension-Data from the European Pediatric Pulmonary Vascular Disease Network.

Echocardiography 2018 06 5;35(6):841-848. Epub 2018 Mar 5.

Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1111/echo.13852DOI Listing
June 2018

First-in-child use of the oral soluble guanylate cyclase stimulator riociguat in pulmonary arterial hypertension.

Pulm Circ 2018 Jan-Mar;8(1):2045893217743123. Epub 2017 Nov 3.

1 Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1177/2045893217743123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731721PMC
November 2017

Future Applications of the Selective Prostacyclin (IP) Receptor Agonist Selexipag in Pediatric Pulmonary Hypertension.

Pediatr Cardiol 2017 10 7;38(7):1523-1524. Epub 2017 Aug 7.

Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.

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http://link.springer.com/10.1007/s00246-017-1699-1
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http://dx.doi.org/10.1007/s00246-017-1699-1DOI Listing
October 2017

First-in-child use of the oral selective prostacyclin IP receptor agonist selexipag in pulmonary arterial hypertension.

Pulm Circ 2017 Apr-Jun;7(2):551-554. Epub 2017 May 12.

Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1177/2045893217703369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467934PMC
May 2017

Pulmonary Hypertension in Infants, Children, and Young Adults.

Authors:
Georg Hansmann

J Am Coll Cardiol 2017 May;69(20):2551-2569

Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2017.03.575DOI Listing
May 2017

PPARγ Links BMP2 and TGFβ1 Pathways in Vascular Smooth Muscle Cells, Regulating Cell Proliferation and Glucose Metabolism.

Cell Metab 2017 May;25(5):1118-1134.e7

Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover 30625, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2017.03.011DOI Listing
May 2017

Normal Reference Values and z Scores of the Pulmonary Artery Acceleration Time in Children and Its Importance for the Assessment of Pulmonary Hypertension.

Circ Cardiovasc Imaging 2017 Jan;10(1)

From the Division of Pediatric Cardiology, Department of Pediatrics (M.K., G.G., A.G., M.G., A.B.), Institute for Medical Informatics, Statistics and Documentation (A.A.), and Centre of Physiological Medicine (G.C.), Medical University Graz, Austria; and Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover, Germany (G.H.).

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http://dx.doi.org/10.1161/CIRCIMAGING.116.005336DOI Listing
January 2017

Diagnostics in Children and Adolescents with Suspected or Confirmed Pulmonary Hypertension.

Paediatr Respir Rev 2017 Jun 26;23:3-15. Epub 2016 Oct 26.

Department of Paediatric Cardiology, University of Münster, Germany.

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http://dx.doi.org/10.1016/j.prrv.2016.10.006DOI Listing
June 2017

Left Ventricular Diastolic Dysfunction in Pediatric Pulmonary Hypertension.

Authors:
Georg Hansmann

Circ Cardiovasc Imaging 2016 09;9(9)

From the Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Germany.

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http://dx.doi.org/10.1161/CIRCIMAGING.116.005527DOI Listing
September 2016

Transthoracic echocardiography in the evaluation of pediatric pulmonary hypertension and ventricular dysfunction.

Pulm Circ 2016 Mar;6(1):15-29

Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1086/685051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860554PMC
March 2016

Right ventricular outflow tract velocity time integral (RVOT VTI) and tricuspid regurgitation velocity/RVOT VTI ratio in pediatric pulmonary hypertension.

Int J Cardiol 2016 Jun 24;212:274-6. Epub 2016 Mar 24.

Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1016/j.ijcard.2016.03.111DOI Listing
June 2016

Recent Advances in the Treatment of Preterm Newborn Infants with Patent Ductus Arteriosus.

Clin Perinatol 2016 Mar;43(1):113-29

Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Carl-Neuberg-Str. 1, Hannover 30625, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.clp.2015.11.008DOI Listing
March 2016

Echocardiographic Reference Values for Right Atrial Size in Children with and without Atrial Septal Defects or Pulmonary Hypertension.

Pediatr Cardiol 2016 Apr 26;37(4):686-95. Epub 2015 Dec 26.

Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1007/s00246-015-1332-0DOI Listing
April 2016

Natural History of Patent Ductus Arteriosus in Very Low Birth Weight Infants after Discharge.

J Pediatr 2015 Nov 1;167(5):1149-51. Epub 2015 Aug 1.

Department of Neonatology, Charité University Medical Center, Berlin, Germany.

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http://dx.doi.org/10.1016/j.jpeds.2015.06.032DOI Listing
November 2015

The Sugen 5416/hypoxia mouse model of pulmonary hypertension revisited: long-term follow-up.

Pulm Circ 2014 Dec;4(4):619-29

Department of Medicine, Division of Newborn Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.

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http://journals.sagepub.com/doi/10.1086/678508
Publisher Site
http://dx.doi.org/10.1086/678508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278622PMC
December 2014

Platelet-rich plasma for the treatment of patent ductus arteriosus: not quite ready for prime time.

Cardiol Young 2015 Jan 27;25(1):139-40. Epub 2014 Aug 27.

2Department of Pediatric Cardiology and Critical CareHannover Medical School,Hannover,Germany.

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http://dx.doi.org/10.1017/S1047951114001516DOI Listing
January 2015

Interdisciplinary networks for the treatment of childhood pulmonary vascular disease: what pulmonary hypertension doctors can learn from pediatric oncologists.

Authors:
Georg Hansmann

Pulm Circ 2013 Dec;3(4):792-801

Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1086/674766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070820PMC
December 2013

Registries for paediatric pulmonary hypertension.

Eur Respir J 2013 Sep;42(3):580-3

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http://dx.doi.org/10.1183/09031936.00065713DOI Listing
September 2013

Thrombocytopenia in the first 24 hours after birth and incidence of patent ductus arteriosus.

Pediatrics 2012 Sep 6;130(3):e623-30. Epub 2012 Aug 6.

Department of Neonatology, Charité University Medical Center, Berlin, Germany.

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http://dx.doi.org/10.1542/peds.2012-0499DOI Listing
September 2012

Mesenchymal stem cell-mediated reversal of bronchopulmonary dysplasia and associated pulmonary hypertension.

Pulm Circ 2012 Apr-Jun;2(2):170-81

Department of Pediatrics, Division of Newborn Medicine, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.4103/2045-8932.97603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401871PMC
August 2012

Non-Invasive Imaging for Congenital Heart Disease: Recent Innovations in Transthoracic Echocardiography.

J Clin Exp Cardiolog 2012 Jan;Suppl 8

Division of Pediatric Cardiology, Department of Pediatrics, Medical University Graz, Austria.

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http://dx.doi.org/10.4172/2155-9880.S8-002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806133PMC
January 2012

Design and validation of an endothelial progenitor cell capture chip and its application in patients with pulmonary arterial hypertension.

J Mol Med (Berl) 2011 Oct 7;89(10):971-83. Epub 2011 Jul 7.

Department of Cardiology, Children's Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1007/s00109-011-0779-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306233PMC
October 2011

Engineered alginate hydrogels for effective microfluidic capture and release of endothelial progenitor cells from whole blood.

Langmuir 2011 Apr 14;27(7):4257-64. Epub 2011 Mar 14.

Department of Chemical Engineering, Northeastern University, Boston, Massachusetts 02115, United States.

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http://dx.doi.org/10.1021/la105016aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086588PMC
April 2011

Patent ductus arteriosus of the preterm infant.

Pediatrics 2010 May 26;125(5):1020-30. Epub 2010 Apr 26.

Department of Pediatrics, Emory University, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1542/peds.2009-3506DOI Listing
May 2010

PPARgamma activation: a potential treatment for pulmonary hypertension.

Sci Transl Med 2009 Dec;1(12):12ps14

Department of Cardiology, Children's Hospital Boston, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1126/scitranslmed.3000267DOI Listing
December 2009

Systematic underestimation of oxygen delivery in ventilated preterm infants.

Neonatology 2010 Jun 2;98(1):18-22. Epub 2009 Dec 2.

Neonatal Intensive Care Unit, Policlinico S. Maria alle Scotte, Azienda Ospedaliera Universitaria Senese, Siena, Italy. claudiodefelix @ hotmail.it

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https://www.karger.com/Article/FullText/262482
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http://dx.doi.org/10.1159/000262482DOI Listing
June 2010

The protective role of adiponectin in pulmonary vascular disease.

Am J Physiol Lung Cell Mol Physiol 2010 Jan 30;298(1):L1-2. Epub 2009 Oct 30.

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http://dx.doi.org/10.1152/ajplung.00367.2009DOI Listing
January 2010

Arrival and survival of a 3-week-old boy from Pakistan with an arterial oxygen saturation of 17%.

BMJ Case Rep 2009 17;2009. Epub 2009 Mar 17.

Department of Cardiology, Children's Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1136/bcr.07.2008.0500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030105PMC
November 2011

Pulmonary arterial hypertension is linked to insulin resistance and reversed by peroxisome proliferator-activated receptor-gamma activation.

Circulation 2007 Mar 5;115(10):1275-84. Epub 2007 Mar 5.

Department of Pediatrics, Division of Pediatric Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.106.663120DOI Listing
March 2007

Neonatal resuscitation on air: it is time to turn down the oxygen tanks [corrected].

Authors:
Georg Hansmann

Lancet 2004 Oct 9-15;364(9442):1293-4

Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/S0140-6736(04)17203-6DOI Listing
November 2004

Inhibition of hypoxia-induced apoptosis by modulation of retinoblastoma protein-dependent signaling in cardiomyocytes.

Circ Res 2002 Nov;91(9):782-9

Department of Cardiology, Campus Virchow Clinic, Charité, Humboldt University, and the Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.

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http://dx.doi.org/10.1161/01.res.0000041030.98642.41DOI Listing
November 2002