Georg Brabant

Georg Brabant

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Georg Brabant

Georg Brabant

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A Comprehensive Molecular Characterization of the Pancreatic Neuroendocrine Tumor Cell Lines BON-1 and QGP-1.

Cancers (Basel) 2020 Mar 14;12(3). Epub 2020 Mar 14.

First Department of Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, D-23538 Lübeck, Germany.

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http://dx.doi.org/10.3390/cancers12030691DOI Listing
March 2020

CD5L constitutes a novel biomarker for integrated hepatic thyroid hormone action.

Thyroid 2020 Mar 18. Epub 2020 Mar 18.

Universitätsklinikum Schleswig-Holstein, CBBM Molecular Endocrinology, Ratzeburger Allee 160, Lübeck, Germany, 23562.

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http://dx.doi.org/10.1089/thy.2019.0635DOI Listing
March 2020

Patients with mutations of the Thyroid hormone beta-receptor show an ADHD-like phenotype for performance monitoring: an electrophysiological study.

Neuroimage Clin 2020 Mar 19;26:102250. Epub 2020 Mar 19.

Department of Neurology, University of Lübeck, Lübeck, Germany; Department of Psychology II, University of Lübeck, Lübeck, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2020.102250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109456PMC
March 2020

The Influence of Thyroid Hormones on Brain Structure and Function in Humans.

Exp Clin Endocrinol Diabetes 2020 Feb 10. Epub 2020 Feb 10.

Department of Neurology, University of Lübeck, Lübeck, Germany.

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http://dx.doi.org/10.1055/a-1101-9090DOI Listing
February 2020

A Thyroid Hormone-Independent Molecular Fingerprint of 3,5-Diiodothyronine Suggests a Strong Relationship with Coffee Metabolism in Humans.

Thyroid 2019 Dec 11;29(12):1743-1754. Epub 2019 Nov 11.

Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.1089/thy.2018.0549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918876PMC
December 2019

[Hypoparathyroidism - un underestimated problem?]

MMW Fortschr Med 2019 12;161(Suppl 7):12-20

MVZ Endokrinologikum Göttingen, Zentrum für Hormon- und Stoffwechselerkrankungen, Nuklearmedizin und Humangenetik, Göttingen, Deutschland.

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http://dx.doi.org/10.1007/s15006-019-1174-4DOI Listing
December 2019

Unraveling the Molecular Basis for Successful Thyroid Hormone Replacement Therapy: The Need for New Thyroid Tissue- and Pathway-Specific Biomarkers.

Exp Clin Endocrinol Diabetes 2019 Oct 7. Epub 2019 Oct 7.

Medizinische Klinik I, Universitätsklinikum Schleswig-Holstein, Lübeck, Germany.

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http://dx.doi.org/10.1055/a-1012-8484DOI Listing
October 2019

Thyroid Related Quality of Life in Elderly with Subclinical Hypothyroidism and Improvement on Levothyroxine is Distinct from that in Young Patients (TSAGE).

Horm Metab Res 2019 Sep 10;51(9):568-574. Epub 2019 Sep 10.

Department of Endocrinology, Diabetes and Metabolism, Clinical Chemistry - Division of Laboratory Research, University Hospital Essen, University Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1055/a-0897-8785DOI Listing
September 2019

Long-Term Endocrine and Metabolic Consequences of Cancer Treatment: A Systematic Review.

Endocr Rev 2019 06;40(3):711-767

Experimental and Clinical Endocrinology, University Hospital of Schleswig-Holstein, Campus Luebeck, Luebeck, Germany.

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https://academic.oup.com/edrv/advance-article/doi/10.1210/er
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http://dx.doi.org/10.1210/er.2018-00092DOI Listing
June 2019

Experimentally induced subclinical hypothyroidism causes decreased functional connectivity of the cuneus: A resting state fMRI study.

Psychoneuroendocrinology 2019 04 12;102:158-163. Epub 2018 Dec 12.

Department of Neurology, University of Lübeck, Lübeck, Germany; Department of Psychology II, University of Lübeck, Lübeck, Germany.

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http://dx.doi.org/10.1016/j.psyneuen.2018.12.012DOI Listing
April 2019

Metabolic Syndrome in Thyroid Disease.

Front Horm Res 2018 5;49:48-66. Epub 2018 Apr 5.

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http://dx.doi.org/10.1159/000485996DOI Listing
January 2019

The corticosteroid prednisolone increases amygdala and insula reactivity to food approach signals in healthy young men.

Psychoneuroendocrinology 2019 01 8;99:154-165. Epub 2018 Sep 8.

Department of Internal Medicine I, University of Lübeck, Lübeck, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S03064530173149
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http://dx.doi.org/10.1016/j.psyneuen.2018.09.007DOI Listing
January 2019

Melatonin secretion following brain midline irradiation is diminished, but not correlated with subjective sleep disturbances.

Clin Endocrinol (Oxf) 2018 12 2;89(6):870-877. Epub 2018 Aug 2.

Department of Neurosurgery, University Hospital RWTH Aachen, Aachen, Germany.

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http://doi.wiley.com/10.1111/cen.13814
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http://dx.doi.org/10.1111/cen.13814DOI Listing
December 2018

2018 European Thyroid Association (ETA) Guidelines on the Diagnosis and Management of Central Hypothyroidism.

Eur Thyroid J 2018 Oct 19;7(5):225-237. Epub 2018 Jul 19.

Department of Pediatric Endocrinology, Emma Children's Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

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https://www.karger.com/Article/FullText/491388
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http://dx.doi.org/10.1159/000491388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198777PMC
October 2018

A Copeptin-Based Approach in the Diagnosis of Diabetes Insipidus.

N Engl J Med 2018 Aug;379(5):428-439

From the University of Leipzig, Department of Endocrinology and Nephrology (W.F., A.T.), and Leipzig University Medical Center, Integrated Research and Treatment Center Adiposity Diseases (W.F.), Leipzig, the Department of Internal Medicine I, Division of Endocrinology and Diabetes, University Hospital, University of Würzburg (I.C., M.K., M.F.), and the Clinical Trial Center (U.M.) and Central Laboratory (M.F.), University Hospital Würzburg, Würzburg, Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-Universität, Munich (J.S.), the Department of Neurosurgery, University Hospital Hamburg-Eppendorf, Hamburg (J.F.), and Experimental and Clinical Endocrinology, University Hospital Lübeck, Lübeck (G.B.) - all in Germany; the Clinic of Endocrinology, Diabetology and Metabolism (J.R., I.S., B.W., E.C., M.C.-C.) and the Clinical Trial Unit (D.R.V.), Department of Clinical Research, University of Basel and University Hospital Basel, Basel, the Department of Endocrinology, Kantonsspital St. Gallen, St. Gallen (T.D., S.B.), the Department of Endocrinology, Inselspital Bern, Bern (E.C.), the Department of Endocrinology, Luzerner Kantonsspital, Lucerne (C.H., S.F.), and the Division of Endocrinology, Diabetology and Metabolism, Medical University Clinic, Kantonsspital Aarau, Aarau (B.M.) - all in Switzerland; and Faculdade de Medicina da UFMG, Universidade Federal de Minas Gerais (J.D., A.R.-O.), and Hermes Pardini Institute (J.D.), Belo Horizonte, Brazil.

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http://dx.doi.org/10.1056/NEJMoa1803760DOI Listing
August 2018

MicroRNA analysis of gastroenteropancreatic neuroendocrine tumors and metastases.

Oncotarget 2018 Jun 19;9(47):28379-28390. Epub 2018 Jun 19.

Department of Pathology, Section of Hematopathology and Endocrine Pathology, University Hospital of Schleswig-Holstein, Lübeck 23538, Germany.

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http://dx.doi.org/10.18632/oncotarget.25357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033345PMC
June 2018

Pheochromocytoma and paraganglioma: genotype versus anatomic location as determinants of tumor phenotype.

Cell Tissue Res 2018 05 24;372(2):347-365. Epub 2018 Jan 24.

Medical Department 1, University Medical Center Schleswig-Holstein, Lübeck, Germany.

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http://dx.doi.org/10.1007/s00441-017-2760-3DOI Listing
May 2018

Effects of thyroid hormones on thermogenesis and energy partitioning.

J Mol Endocrinol 2018 04 6;60(3):R157-R170. Epub 2018 Feb 6.

Medizinische Klinik IExperimentelle und Klinische Endokrinologie, Universität zu Lübeck, Lübeck, Germany

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http://dx.doi.org/10.1530/JME-17-0319DOI Listing
April 2018

Comprehensive assessment of sex hormones in Takotsubo syndrome.

Int J Cardiol 2018 Jan;250:11-15

Department of Cardiology, Angiology and Intensive Care Medicine, Medical Clinic II, University Heart Center Lübeck, Lübeck, Germany; German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck, Lübeck, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.10.047DOI Listing
January 2018

Differential regulation of monocarboxylate transporter 8 expression in thyroid cancer and hyperthyroidism.

Eur J Endocrinol 2017 Sep 2;177(3):243-250. Epub 2017 Jun 2.

Department of Endocrinology and Metabolism and Division of Laboratory Research, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1530/EJE-17-0279DOI Listing
September 2017

Copeptin as a marker of an altered CRH axis in pituitary disease.

Endocrine 2017 Sep 9;57(3):474-480. Epub 2017 Aug 9.

Experimental and Clinical Endocrinology Med Clinic I, University of Luebeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.

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http://link.springer.com/10.1007/s12020-017-1366-6
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http://dx.doi.org/10.1007/s12020-017-1366-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573756PMC
September 2017

Plasma proteome and metabolome characterization of an experimental human thyrotoxicosis model.

BMC Med 2017 Jan 9;15(1). Epub 2017 Jan 9.

Medical Clinic I, University of Lübeck, Experimental and Clinical Endocrinology, Ratzeburger Allee 160, Zentralklinikum (Haus 40), 23538, Lübeck, Germany.

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http://dx.doi.org/10.1186/s12916-016-0770-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220622PMC
January 2017

Thermoregulatory and Cardiovascular Consequences of a Transient Thyrotoxicosis and Recovery in Male Mice.

Endocrinology 2016 07 4;157(7):2957-67. Epub 2016 May 4.

Department of Cell and Molecular Biology (C.S.H., L.H., M.M., B.V., J.M.), Karolinska Institutet, Stockholm, Sweden 17177; Institute of Experimental Endocrinology (C.S.H.), Charité-University Hospital Berlin, Berlin, Germany 13353; Center of Brain, Behavior and Metabolism CBBM/Medizinische Klinik I (L.H., R.O., G.B., J.M.), University of Lübeck, Lübeck, Germany 23562; and Medizinische Klinik II (M.M.), University of Lübeck, Lübeck, Germany 23562.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
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http://dx.doi.org/10.1210/en.2016-1095DOI Listing
July 2016

Prednisolone increases neural reactivity to negative socio-emotional stimuli in healthy young men.

Eur Neuropsychopharmacol 2016 07 11;26(7):1176-89. Epub 2016 May 11.

Department of Neurology, University of Lübeck, Lübeck, Germany; Institute of Psychology II, University of Lübeck, Lübeck, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2016.04.010DOI Listing
July 2016

Copeptin under glucagon stimulation.

Endocrine 2016 May 17;52(2):344-51. Epub 2015 Nov 17.

Experimental and Clinical Endocrinology Med Clinic I, University of Luebeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.

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http://dx.doi.org/10.1007/s12020-015-0783-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824796PMC
May 2016

Association of sex hormones with incident 10-year cardiovascular disease and mortality in women.

Maturitas 2015 Dec 28;82(4):424-30. Epub 2015 Aug 28.

Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Greifswald, University Medicine Greifswald, Greifswald, Germany; European University of Applied Sciences, Faculty of Applied Public Health, Rostock, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.maturitas.2015.08.009DOI Listing
December 2015

Endogenous Androgens and Sex Hormone-Binding Globulin in Women and Risk of Metabolic Syndrome and Type 2 Diabetes.

J Clin Endocrinol Metab 2015 Dec 7;100(12):4595-603. Epub 2015 Oct 7.

Institute of Clinical Chemistry and Laboratory Medicine (B.F., H.K. H.W., M.N., R.H.), DZHK (German Centre for Cardiovascular Research) (S.G., H.W., H.V., M.D., M.N., R.H.), Greifswald, Germany 17475, Institute for Community Medicine (H.V.), Department of Cardiology (S.G., M.D.), University Medicine Greifswald, Germany 17475; Department of Clinical Chemistry (B.G.K.), University Hospital, South Manchester, United Kingdom M23 9LT; Department of Internal Medicine I (G.B.), University Lübeck, Germany 23562; and European University of Applied Sciences (R.H.), Faculty of Applied Public Health, Rostock, Germany 18057.

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http://dx.doi.org/10.1210/jc.2015-2546DOI Listing
December 2015

Effect of Experimental Thyrotoxicosis on Brain Gray Matter: A Voxel-Based Morphometry Study.

Eur Thyroid J 2015 Sep 30;4(Suppl 1):113-8. Epub 2015 May 30.

Department of Neurology, University of Lübeck, Lübeck, Germany.

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https://www.karger.com/Article/FullText/398793
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http://dx.doi.org/10.1159/000398793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640290PMC
September 2015

Effect of Experimental Thyrotoxicosis onto Blood Coagulation: A Proteomics Study.

Eur Thyroid J 2015 Sep 28;4(Suppl 1):119-24. Epub 2015 May 28.

Interfaculty Institute for Genetics and Functional Genomics, Greifswald, Germany.

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http://dx.doi.org/10.1159/000381769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640288PMC
September 2015

Self-reported endocrine late effects in adults treated for brain tumours, Hodgkin and non-Hodgkin lymphoma: a registry based study in Northern Germany.

Eur J Endocrinol 2015 Aug 6;173(2):139-48. Epub 2015 May 6.

Experimental and Clinical EndocrinologyDepartment of Internal Medicine I, University Hospital of Schleswig-Holstein, Campus Luebeck, Ratzeburger Allee 160, 23538 Luebeck, GermanyInstitute of Social Medicine and EpidemiologyUniversity Luebeck, Ratzeburger Allee 160, 23538 Luebeck, GermanyDepartment of Pediatric Hematology and OncologyUniversity Hospital of Schleswig-Holstein, Campus Luebeck, Ratzeburger Allee 160, 23538 Luebeck, GermanyDepartment of NeurosurgeryUniversity Hospital of Essen, Hufelandstr. 55, 45147 Essen, Germany andInstitute of Cancer Epidemiology e.V.University Luebeck, Ratzeburger Allee 160, 23538 Luebeck, Germany

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http://dx.doi.org/10.1530/EJE-15-0174DOI Listing
August 2015

Management of subclinical hypothyroidism in pregnancy: are we too simplistic?

Eur J Endocrinol 2015 Jul 3;173(1):P1-P11. Epub 2015 Feb 3.

Experimental and Clinical EndocrinologyUniversity of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, GermanyDepartment of EndocrinologyUniversity of Manchester, Manchester, UKDepartment of Internal MedicineRotterdam Thyroid Center, Erasmus Medical Center, Rotterdam, The NetherlandsDepartment of Obstetrics and GynaecologyNational University of Singapore, Singapore, SingaporeInstituto de Investigaciones BiomedicasConsejo Superior de Investigaciones Cientificas and Universidad Autonoma de Madrid, Madrid, SpainCenter for Biomedical Research on Rare DiseasesMadrid, SpainPierre et Marie Curie UniversityParis, FranceDepartment of Clinical Medicine and SurgeryUniversity of Naples 'Federico II', Naples 80131, ItalyCollege of Medical and Dental SciencesInstitute for Biomedical Research, Centre for Endocrinology, Diabetes and Metabolism, Level 2, University of Birmingham, Birmingham B15 2TT, UKDepartment of EndocrinologyInstitute of Clinical Medicine, Aalborg University Hospital, Aalborg University, Aalborg, Denmark.

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https://eje.bioscientifica.com/view/journals/eje/173/1/P1.xm
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http://dx.doi.org/10.1530/EJE-14-1005DOI Listing
July 2015

CUP Syndrome in Neuroendocrine Neoplasia: Analysis of Risk Factors and Impact of Surgical Intervention.

World J Surg 2015 Jun;39(6):1443-51

Department for Surgery, University Hospital Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany,

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http://link.springer.com/10.1007/s00268-015-2963-2
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http://dx.doi.org/10.1007/s00268-015-2963-2DOI Listing
June 2015

Experimentally induced thyrotoxicosis leads to increased connectivity in temporal lobe structures: a resting state fMRI study.

Psychoneuroendocrinology 2015 Jun 12;56:100-9. Epub 2015 Mar 12.

Department of Neurology, University of Lübeck, Lübeck, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.psyneuen.2015.03.009DOI Listing
June 2015

Oncogenic mutations and chromosomal aberrations in primary extranodal diffuse large B-cell lymphomas of the thyroid--a study of 21 cases.

J Clin Endocrinol Metab 2015 Feb 25;100(2):754-62. Epub 2014 Nov 25.

Department of Pathology, Reference Centre for Lymph Node Pathology and Hematopathology (J.K., V.B., J.S., K.R., A.C.F., C.T.), Department of Internal Medicine I (N.G., J.G., G.B., H.L.), and Department of Radiation Oncology (D.R.), University Hospital of Schleswig-Holstein, Campus Luebeck, 23538 Luebeck, Germany.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2014-3250DOI Listing
February 2015

Genomic landscape of pancreatic neuroendocrine tumors.

World J Gastroenterol 2014 Dec;20(46):17498-506

Niklas Gebauer, Christian Schmidt-Werthern, Veronica Bernard, Alfred C Feller, Christoph Thorns, Department of Pathology, University Hospital of Schleswig-Holstein, 23538 Luebeck, Germany.

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http://dx.doi.org/10.3748/wjg.v20.i46.17498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265611PMC
December 2014

Detection of 3,5-diiodothyronine in sera of patients with altered thyroid status using a new monoclonal antibody-based chemiluminescence immunoassay.

Thyroid 2014 Sep 1;24(9):1350-60. Epub 2014 Aug 1.

1 Institute for Experimental Endocrinology, Charité-Universitätsmedizin Berlin , Berlin, Germany .

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http://dx.doi.org/10.1089/thy.2013.0688DOI Listing
September 2014

The association between IGF-I/IGFBP-3 and subclinical end points: epidemiology faces the limits.

J Clin Endocrinol Metab 2014 Aug 13;99(8):2804-12. Epub 2014 May 13.

Institute of Clinical Chemistry and Laboratory Medicine (C.M., H.W., M.N., N.F.) and Department of Prosthetic Dentistry, Gerodontology, and Biomaterials (S.S.), Center of Oral Health, University Medicine Greifswald, 17475 Greifswald, Germany; Med Clinic I (G.B.), University of Lübeck, 23538 Lübeck, Germany; and Klinik für Innere Medizin I (U.W.), Evangelisches Waldkrankenhaus Spandau, 13589 Berlin, Germany.

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http://dx.doi.org/10.1210/jc.2013-3746DOI Listing
August 2014

Global microRNA profiling of pancreatic neuroendocrine neoplasias.

Anticancer Res 2014 May;34(5):2249-54

Institut für Pathologie, Universität zu Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.

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May 2014

2013 ETA Guideline: Management of Subclinical Hypothyroidism.

Eur Thyroid J 2013 Dec 27;2(4):215-28. Epub 2013 Nov 27.

Clinique Endocrinologique Marc Linquette, CHU, Lille, France.

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http://dx.doi.org/10.1159/000356507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923601PMC
December 2013

Cross-sectional and longitudinal associations between insulin-like growth factor I and metabolic syndrome: a general population study in German adults.

Diabetes Metab Res Rev 2013 Sep;29(6):452-62

Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße NK, D-17475, Greifswald, Germany.

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http://dx.doi.org/10.1002/dmrr.2412DOI Listing
September 2013

Inhibiting the phosphatidylinositide 3-kinase pathway blocks radiation-induced metastasis associated with Rho-GTPase and Hypoxia-inducible factor-1 activity.

Radiother Oncol 2013 Sep 25;108(3):548-53. Epub 2013 Jul 25.

Hypoxia and Therapeutics Group, Manchester Pharmacy School, University of Manchester, UK.

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http://dx.doi.org/10.1016/j.radonc.2013.06.027DOI Listing
September 2013

Positive association between testosterone, blood pressure, and hypertension in women: longitudinal findings from the Study of Health in Pomerania.

J Hypertens 2013 Jun;31(6):1106-13

Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, D-17489 Greifswald, Germany.

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http://dx.doi.org/10.1097/HJH.0b013e3283603eb1DOI Listing
June 2013

Thyroid hormones and the metabolic syndrome.

Eur Thyroid J 2013 Jun 28;2(2):83-92. Epub 2013 May 28.

Medizinische Klinik I, Experimentelle und Klinische Endokrinologie, Universität zu Lübeck, Lübeck, Germany ; Department of Endocrinology, The Christie Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1159/000351249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821514PMC
June 2013

Response to GH treatment in adult GH deficiency is predicted by gender, age, and IGF1 SDS but not by stimulated GH-peak.

Eur J Endocrinol 2013 May 15;168(5):733-43. Epub 2013 Apr 15.

Department of Medical Endocrinology, PE 2132, Rigshospitalet, National University Hospital, Copenhagen University, Copenhagen, Denmark.

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http://dx.doi.org/10.1530/EJE-13-0005DOI Listing
May 2013

Serum bile acids and leptin interact with glucose metabolism in patients with liver cirrhosis.

Clin Nutr 2013 Feb 6;32(1):122-9. Epub 2012 Jul 6.

Charité - Universitätsmedizin Berlin, Department of Gastroenterology, Infectiology and Rheumatology (incl. section on Clinical Nutrition), Charitéplatz 1, Berlin 10117, Germany.

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http://dx.doi.org/10.1016/j.clnu.2012.06.006DOI Listing
February 2013

A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.

Authors:
Andrea D Coviello Robin Haring Melissa Wellons Dhananjay Vaidya Terho Lehtimäki Sarah Keildson Kathryn L Lunetta Chunyan He Myriam Fornage Vasiliki Lagou Massimo Mangino N Charlotte Onland-Moret Brian Chen Joel Eriksson Melissa Garcia Yong Mei Liu Annemarie Koster Kurt Lohman Leo-Pekka Lyytikäinen Ann-Kristin Petersen Jennifer Prescott Lisette Stolk Liesbeth Vandenput Andrew R Wood Wei Vivian Zhuang Aimo Ruokonen Anna-Liisa Hartikainen Anneli Pouta Stefania Bandinelli Reiner Biffar Georg Brabant David G Cox Yuhui Chen Steven Cummings Luigi Ferrucci Marc J Gunter Susan E Hankinson Hannu Martikainen Albert Hofman Georg Homuth Thomas Illig John-Olov Jansson Andrew D Johnson David Karasik Magnus Karlsson Johannes Kettunen Douglas P Kiel Peter Kraft Jingmin Liu Östen Ljunggren Mattias Lorentzon Marcello Maggio Marcello R P Markus Dan Mellström Iva Miljkovic Daniel Mirel Sarah Nelson Laure Morin Papunen Petra H M Peeters Inga Prokopenko Leslie Raffel Martin Reincke Alex P Reiner Kathryn Rexrode Fernando Rivadeneira Stephen M Schwartz David Siscovick Nicole Soranzo Doris Stöckl Shelley Tworoger André G Uitterlinden Carla H van Gils Ramachandran S Vasan H-Erich Wichmann Guangju Zhai Shalender Bhasin Martin Bidlingmaier Stephen J Chanock Immaculata De Vivo Tamara B Harris David J Hunter Mika Kähönen Simin Liu Pamela Ouyang Tim D Spector Yvonne T van der Schouw Jorma Viikari Henri Wallaschofski Mark I McCarthy Timothy M Frayling Anna Murray Steve Franks Marjo-Riitta Järvelin Frank H de Jong Olli Raitakari Alexander Teumer Claes Ohlsson Joanne M Murabito John R B Perry

PLoS Genet 2012 19;8(7):e1002805. Epub 2012 Jul 19.

Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1002805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400553PMC
January 2013

The atrial natriuretic peptide does not serve osmoregulation but predicts outcome following brain injury.

Acta Neurochir Suppl 2012 ;114:277-81

Department of Neurosurgery, University of Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1007/978-3-7091-0956-4_54DOI Listing
May 2012

Hypothyroidism following childhood cancer therapy-an under diagnosed complication.

Int J Cancer 2012 Mar 9;130(5):1145-50. Epub 2011 Jun 9.

Department of Endocrinology, The Christie NHS Foundation Trust, Manchester, United Kingdom.

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March 2012

Plasma bile acids are associated with energy expenditure and thyroid function in humans.

J Clin Endocrinol Metab 2012 Feb 7;97(2):535-42. Epub 2011 Dec 7.

Department of Gastroenterology, Hepatology, Endocrinology, and Nutrition, Klinikum Bremen Mitte, St. Juergen Strasse 1, D-28177 Bremen, Germany.

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http://dx.doi.org/10.1210/jc.2011-2329DOI Listing
February 2012

Age-specific reference ranges for serum testosterone and androstenedione concentrations in women measured by liquid chromatography-tandem mass spectrometry.

J Clin Endocrinol Metab 2012 Feb 7;97(2):408-15. Epub 2011 Dec 7.

Institute of Clinical Chemistry and Laboratory Medicine, University of Greifswald, Ferdinand-Sauerbruch-Strasse, D-17475 Greifswald, Germany.

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February 2012

GDC-0941 inhibits metastatic characteristics of thyroid carcinomas by targeting both the phosphoinositide-3 kinase (PI3K) and hypoxia-inducible factor-1α (HIF-1α) pathways.

J Clin Endocrinol Metab 2011 Dec 12;96(12):E1934-43. Epub 2011 Oct 12.

Hypoxia and Therapeutics Group, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, United Kingdom.

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http://dx.doi.org/10.1210/jc.2011-1426DOI Listing
December 2011

Hypoxia-inducible factor in thyroid carcinoma.

J Thyroid Res 2011 16;2011:762905. Epub 2011 Jun 16.

Hypoxia and Therapeutics Group, School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134378PMC
November 2011

Comparison of serum cortisol measurement by immunoassay and liquid chromatography-tandem mass spectrometry in patients receiving the 11β-hydroxylase inhibitor metyrapone.

Ann Clin Biochem 2011 Sep 3;48(Pt 5):441-6. Epub 2011 Aug 3.

Biochemistry Department, The Christie NHS Foundation Trust, Withington, Manchester M20 4BX, UK.

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September 2011

Serum insulin-like growth factor I and its binding protein 3 in their relation to intima-media thickness: results of the study of health in Pomerania (SHIP).

Clin Endocrinol (Oxf) 2011 Jul;75(1):70-5

Institute of Clinical Chemistry and Laboratory MedicineDepartment of CardiologyDepartment of NeurologyInstitute for Community Medicine University of Greifswald, GermanyDepartment of Endocrinology, Christie Hospital, Manchester, UK.

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July 2011

The interface between thyroid and diabetes mellitus.

Clin Endocrinol (Oxf) 2011 Jul;75(1):1-9

Endocrine Unit, Evgenidion Hospital, University of Athens Medical School, Athens, GreeceService d' Endocrinologie-Diabète-Maladies Métaboliques, Centre Hospitalier, Lyon-Sud, FranceDepartment of Endocrinology, The Christie, Manchester Academic Health Science Centre, Manchester, UK.

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July 2011

Evidence for extrathyroidal formation of 3-iodothyronamine in humans as provided by a novel monoclonal antibody-based chemiluminescent serum immunoassay.

J Clin Endocrinol Metab 2011 Jun 13;96(6):1864-72. Epub 2011 Apr 13.

Institut für Experimentelle Endokrinologie, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1210/jc.2010-2680DOI Listing
June 2011

Visualizing hormone actions in the brain.

Trends Endocrinol Metab 2011 May 15;22(5):153-63. Epub 2011 Apr 15.

Department of Endocrinology, The Christie, Manchester Academic Health Science Centre, Wilmslow Road, Manchester M20 4BX, UK.

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http://dx.doi.org/10.1016/j.tem.2011.01.004DOI Listing
May 2011

Proinsulin and the proinsulin/insulin ratio in overweight and obese children and adolescents: relation to clinical parameters, insulin resistance, and impaired glucose regulation.

Pediatr Diabetes 2011 May 29;12(3 Pt 2):242-9. Epub 2011 Mar 29.

Department of Pediatric Endocrinology and Diabetology, Charité Universitätsmedizin Berlin, Germany.

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http://dx.doi.org/10.1111/j.1399-5448.2010.00734.xDOI Listing
May 2011

Wnt signaling in estrogen-induced lactotroph proliferation.

J Cell Sci 2011 Feb 18;124(Pt 4):540-7. Epub 2011 Jan 18.

Endocrinology & Diabetes Group, Faculty of Medical & Human Sciences, AV Hill Building, Oxford Road, University of Manchester, Manchester M13 9PT, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031368PMC
February 2011

Doxorubicin fails to eradicate cancer stem cells derived from anaplastic thyroid carcinoma cells: characterization of resistant cells.

Int J Oncol 2010 Aug;37(2):307-15

Division of Endocrinology, Department of Medicine, St Hedwig Hospital and Humboldt University, D-10115 Berlin, Berlin, Germany.

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http://dx.doi.org/10.3892/ijo_00000679DOI Listing
August 2010

Diet-induced obesity, exogenous leptin-, and MADB106 tumor cell challenge affect tissue leukocyte distribution and serum levels of cytokines in F344 rats.

Endocrine 2010 Aug 22;38(1):104-12. Epub 2010 Jun 22.

Institute for Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1007/s12020-010-9358-9DOI Listing
August 2010

TSH Isoforms: About a Case of Hypothyroidism in a Down's Syndrome Young Adult.

J Thyroid Res 2010 Jul 14;2010:703978. Epub 2010 Jul 14.

Laboratoire du Service de Médecine Nucléaire, Centre Hospitalier de Chambéry, 73000 Chambéry, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957696PMC
July 2010

More than a prolactinoma.

Pituitary 2010 ;13(1):87-8

Department of Endocrinology, Christie Hospital, Manchester, UK.

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May 2010

GH/IGF-I regulation in obesity--mechanisms and practical consequences in children and adults.

Horm Res Paediatr 2010 3;73(3):153-60. Epub 2010 Mar 3.

Department of Endocrinology, Christie Hospital, Manchester, UK.

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May 2010

Survivors of childhood cancer. Integrated follow-up is needed.

BMJ 2010 Feb 8;340:c588. Epub 2010 Feb 8.

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February 2010

Association between hepatic steatosis and serum IGF1 and IGFBP-3 levels in a population-based sample.

Eur J Endocrinol 2009 Nov 18;161(5):705-13. Epub 2009 Aug 18.

Institute of Community Medicine Institute of Clinical Chemistry and Laboratory Medicine Institute of Physiology Department of Internal Medicine B, University of Greifswald, Greifswald D-17487, Germany.

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November 2009

Altered phenotype of NK cells from obese rats can be normalized by transfer into lean animals.

Obesity (Silver Spring) 2009 Oct 14;17(10):1848-55. Epub 2009 May 14.

Institute for Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany.

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October 2009

Neuroendocrine function following traumatic brain injury and subsequent intensive care treatment: a prospective longitudinal evaluation.

J Neurotrauma 2009 Sep;26(9):1435-46

Department of Neurosurgery, University Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1089/neu.2008.0601DOI Listing
September 2009

Human growth hormone-related iatrogenic Creutzfeldt-Jakob disease--being aware of diagnostic features 25 years later.

J Clin Endocrinol Metab 2009 Aug;94(8):2684-5

Department of Endocrinology, The Christie, Manchester, United Kingdom.

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August 2009

Mortality and serum insulin-like growth factor (IGF)-I and IGF binding protein 3 concentrations.

J Clin Endocrinol Metab 2009 May 17;94(5):1732-9. Epub 2009 Feb 17.

Institute for Community Medicine, Ernst Moritz Arndt University, D-17487 Greifswald, Germany.

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May 2009

Five commercially available insulin-like growth factor I (IGF-I) assays in comparison to the former Nichols Advantage IGF-I in a growth hormone treated population.

Clin Chem Lab Med 2008 ;46(12):1776-83

Institute of Clinical Chemistry and Laboratory Medicine, Ernst Moritz Arndt University of Greifswald, Greifswald, Germany.

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March 2009

Effects of antiepileptic drug therapy on vitamin D status and biochemical markers of bone turnover in children with epilepsy.

Eur J Pediatr 2008 Dec 13;167(12):1369-77. Epub 2008 Feb 13.

Nutrition Physiology and Human Nutrition Unit, Institute of Food Science, Leibniz University of Hannover, Wunstorfer Str. 14, 30453, Hannover, Germany.

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December 2008

Resistance of Janus kinase-2 dependent leptin signaling in natural killer (NK) cells: a novel mechanism of NK cell dysfunction in diet-induced obesity.

Endocrinology 2008 Jul 20;149(7):3370-8. Epub 2008 Mar 20.

Institute for Functional and Applied Anatomy, Hannover Medical School, Carl-Neuberg Strasse 1, 30625 Hannover, Germany.

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http://dx.doi.org/10.1210/en.2007-1516DOI Listing
July 2008

Central insulin action regulates peripheral glucose and fat metabolism in mice.

J Clin Invest 2008 Jun;118(6):2132-47

Department of Mouse Genetics and Metabolism, Institute for Genetics, University of Cologne, and Center of Molecular Medicine Cologne, Cologne, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2350427PMC
June 2008

Association between serum insulin-like growth factor-I levels and thyroid disorders in a population-based study.

J Clin Endocrinol Metab 2007 Oct 31;92(10):4039-45. Epub 2007 Jul 31.

Institute of Community Medicine, University of Greifswald, D-17487 Greifswald, Germany.

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October 2007

Influence of GH substitution therapy in deficient adults on the recurrence rate of hormonally inactive pituitary adenomas: a case control study.

Eur J Endocrinol 2007 Aug;157(2):149-56

Department of Neurosurgery, University of Erlangen-Nuremberg, Schwabachanlage 6, D-91054 Erlangen, Germany.

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August 2007

GH releasing peptide 2 test: the holy grail of testing GH deficiency?

Authors:
Georg Brabant

Eur J Endocrinol 2007 Jul;157(1):29-30

Department of Endocrinology, Christie Hospital, University of Manchester, Manchester M20 4BX, UK.

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July 2007