Geoffrey L Greene

Geoffrey L Greene

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Geoffrey L Greene

Geoffrey L Greene

Publications by authors named "Geoffrey L Greene"

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Next-Generation ERα Inhibitors for Endocrine-Resistant ER+ Breast Cancer.

Endocrinology 2019 Apr;160(4):759-769

Ben May Department for Cancer Research, The University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1210/en.2018-01095DOI Listing
April 2019

Publisher Correction: Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance.

Nat Rev Cancer 2018 Oct;18(10):662

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1038/s41568-018-0053-0DOI Listing
October 2018

Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer.

Mol Pharmacol 2018 08 8;94(2):812-822. Epub 2018 May 8.

Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (P.Y.M., B.A., P.F., D.M.Q.R., J.A.G., V.C.J.); The Ben May Department for Cancer Research, University of Chicago, Chicago, Illinois (S.W.F., S.S.R., G.L.G.); Department of Oncology, Lombardi Comprehensive Cancer Center, Washington, DC (S.S.); and Institute of Chemistry, Romanian Academy, Timisoara, Romania (R.F.C.)

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http://dx.doi.org/10.1124/mol.117.111385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022805PMC
August 2018

A "cross-stitched" peptide with improved helicity and proteolytic stability.

Org Biomol Chem 2018 05;16(20):3702-3706

Department of Medicinal Chemistry and Pharmacognosy and UI Cancer Center, University of Illinois at Chicago, 833 S. Wood St., Chicago, IL 60612, USA.

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http://dx.doi.org/10.1039/c8ob00790jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993042PMC
May 2018

Interferon-Stimulated Genes Are Transcriptionally Repressed by PR in Breast Cancer.

Mol Cancer Res 2017 10 6;15(10):1331-1340. Epub 2017 Jul 6.

Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas.

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http://dx.doi.org/10.1158/1541-7786.MCR-17-0180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626608PMC
October 2017

Capture of associated targets on chromatin links long-distance chromatin looping to transcriptional coordination.

Nat Commun 2016 09 16;7:12893. Epub 2016 Sep 16.

Ben May Department of Cancer Research, University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1038/ncomms12893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028417PMC
September 2016

The Neutron Enigma.

Sci Am 2016 Apr;314(4):36-41

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http://dx.doi.org/10.1038/scientificamerican0416-36DOI Listing
April 2016

Stapled Peptides with γ-Methylated Hydrocarbon Chains for the Estrogen Receptor/Coactivator Interaction.

Angew Chem Int Ed Engl 2016 Mar 1;55(13):4252-5. Epub 2016 Mar 1.

Department of Medicinal Chemistry and Pharmacognosy and UI Cancer Center, University of Illinois at Chicago, 833 S. Wood St., Chicago, IL, 60612, USA.

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http://dx.doi.org/10.1002/anie.201510557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964982PMC
March 2016

Mapping ERβ genomic binding sites reveals unique genomic features and identifies EBF1 as an ERβ interactor.

PLoS One 2013 8;8(8):e71355. Epub 2013 Aug 8.

Ben May Department for Cancer Research, University of Chicago, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0071355PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738513PMC
April 2014

Examining the pathogenesis of breast cancer using a novel agent-based model of mammary ductal epithelium dynamics.

PLoS One 2013 21;8(5):e64091. Epub 2013 May 21.

Pritzker School of Medicine, University of Chicago, Chicago, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0064091PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660364PMC
December 2013

Prolactin activates ERα in the absence of ligand in female mammary development and carcinogenesis in vivo.

Endocrinology 2013 Dec 24;154(12):4483-92. Epub 2013 Sep 24.

Department of Comparative Biosciences, 2015 Linden Drive, University of Wisconsin-Madison, Madison, WI 53706.

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http://dx.doi.org/10.1210/en.2013-1533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836081PMC
December 2013

In memoriam: Elwood Jensen (1920-2012).

Endocr Rev 2013 Dec;34(6):761-3

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http://dx.doi.org/10.1210/er.2013-1031DOI Listing
December 2013

Cross-talk between the ligand- and DNA-binding domains of estrogen receptor.

Proteins 2013 Nov 19;81(11):1900-9. Epub 2013 Aug 19.

Center for Proteomics and Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, 44106-4988.

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http://dx.doi.org/10.1002/prot.24331DOI Listing
November 2013

In memoriam: Elwood Jensen (1920-2012).

Endocrinology 2013 Oct;154(10):3489-91

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http://dx.doi.org/10.1210/en.2013-1009DOI Listing
October 2013

Overcoming mutation-based resistance to antiandrogens with rational drug design.

Elife 2013 Apr 9;2:e00499. Epub 2013 Apr 9.

Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences , Memorial Sloan-Kettering Cancer Center , New York , United States ; Human Oncology and Pathogenesis Program , Memorial Sloan-Kettering Cancer Center , New York , United States.

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https://elifesciences.org/articles/00499
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http://dx.doi.org/10.7554/eLife.00499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622181PMC
April 2013

The effects of 17β-estradiol and a selective estrogen receptor modulator, bazedoxifene, on ovarian carcinogenesis.

Gynecol Oncol 2012 Jan 11;124(1):134-41. Epub 2011 Oct 11.

Department of Obstetrics and Gynecology, Center for Integrative Science, University of Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.ygyno.2011.08.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249832PMC
January 2012

Removal of lactate dehydrogenase-elevating virus from human-in-mouse breast tumor xenografts by cell-sorting.

J Virol Methods 2011 May 24;173(2):266-70. Epub 2011 Feb 24.

The Ben May Department for Cancer Research, The University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.jviromet.2011.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086718PMC
May 2011

Green tea catechins inhibit angiogenesis through suppression of STAT3 activation.

Breast Cancer Res Treat 2009 Oct 28;117(3):505-15. Epub 2008 Sep 28.

The Ben May Department for Cancer Research, The University of Chicago, GCIS W325D, 929 East 57th Street, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1007/s10549-008-0196-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664280PMC
October 2009

Estrogen-dependent and -independent estrogen receptor-alpha signaling separately regulate male fertility.

Endocrinology 2009 Jun 5;150(6):2898-905. Epub 2009 Mar 5.

The Ben May Department for Cancer Research, The University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1210/en.2008-1016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689797PMC
June 2009

Modulation of alphaCaMKII signaling by rapid ERalpha action.

Brain Res 2008 Jul 23;1222:1-17. Epub 2008 May 23.

The Ben May Department for Cancer Research, The University of Chicago, Chicago, IL 60637, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000689930801125
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http://dx.doi.org/10.1016/j.brainres.2008.05.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597455PMC
July 2008

Inhibition of mammary tumorigenesis in the C3(1)/SV40 mouse model by green tea.

Breast Cancer Res Treat 2008 Feb 5;107(3):359-69. Epub 2007 May 5.

The Ben May Department for Cancer Research, The University of Chicago, GCIS W330, 929 East 57th Street, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1007/s10549-007-9568-xDOI Listing
February 2008

CBP Is a dosage-dependent regulator of nuclear factor-kappaB suppression by the estrogen receptor.

Mol Endocrinol 2008 Feb 11;22(2):263-72. Epub 2007 Oct 11.

Department of Cancer Biology, The Scripps Research Institute, Jupiter, FL 33458, USA.

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http://dx.doi.org/10.1210/me.2007-0324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234588PMC
February 2008

Molecular characterization of a B-ring unsaturated estrogen: implications for conjugated equine estrogen components of premarin.

Steroids 2008 Jan 11;73(1):59-68. Epub 2007 Sep 11.

The Ben May Department for Cancer Research, The University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.steroids.2007.08.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2225582PMC
January 2008

Structural plasticity in the oestrogen receptor ligand-binding domain.

EMBO Rep 2007 Jun 27;8(6):563-8. Epub 2007 Apr 27.

Department of Cancer Biology, The Scripps Research Institute, 5353 Parkside Drive, Jupiter, Florida 33458, USA.

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http://dx.doi.org/10.1038/sj.embor.7400963DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2002528PMC
June 2007

Conformation-specific affinity purification of proteins using engineered binding proteins: application to the estrogen receptor.

Protein Expr Purif 2006 Jun 14;47(2):348-54. Epub 2005 Nov 14.

Department of Biochemistry and Molecular Biology, The University of Chicago, IL 60637, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S104659280500379
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http://dx.doi.org/10.1016/j.pep.2005.10.021DOI Listing
June 2006

Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity.

J Biol Chem 2006 Jun 28;281(26):17909-19. Epub 2006 Apr 28.

Ben May Institute for Cancer Research, University of Chicago W330, 929 E. 57th Street, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1074/jbc.M513684200DOI Listing
June 2006

Recruitment of histone deacetylase 4 to the N-terminal region of estrogen receptor alpha.

Mol Endocrinol 2005 Dec 28;19(12):2930-42. Epub 2005 Jul 28.

The Ben May Institute for Cancer Research, The University of Chicago, Center for Integrative Sciences, Room W330, 929 East 57th Street, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1210/me.2005-0178DOI Listing
December 2005

Label-free detection of protein-protein interactions on biochips.

Angew Chem Int Ed Engl 2005 Aug;44(34):5480-3

Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, 5735 South Ellis Avenue, Chicago, IL 60637, USA.

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http://chemgroups.northwestern.edu/mrksich/pdf/angew_2005_44
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http://doi.wiley.com/10.1002/anie.200501363
Publisher Site
http://dx.doi.org/10.1002/anie.200501363DOI Listing
August 2005

Ligand control of coregulator recruitment to nuclear receptors.

Annu Rev Physiol 2005 ;67:309-33

The University of Chicago, The Ben May Institute for Cancer Research, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1146/annurev.physiol.66.032802.154710DOI Listing
May 2005

Structural basis for an unexpected mode of SERM-mediated ER antagonism.

Mol Cell 2005 May;18(4):413-24

The Ben May Institute for Cancer Research and Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1016/j.molcel.2005.04.014DOI Listing
May 2005

Plasma membrane estrogen receptors exist and functions as dimers.

Mol Endocrinol 2004 Dec 1;18(12):2854-65. Epub 2004 Jul 1.

Long Beach Veterans Affairs Medical Center/University of California-Irvine, 5901 East 7th Street, Long Beach, California 90822, USA.

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http://dx.doi.org/10.1210/me.2004-0115DOI Listing
December 2004

Nuclear receptor ligands and cofactor recruitment: is there a coactivator "on deck"?

Mol Cell 2003 Apr;11(4):850-1

The Ben May Institute for Cancer Research, The University of Chicago, 5841 South Maryland Avenue, MC6027, Illinois 60637, USA.

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http://dx.doi.org/10.1016/s1097-2765(03)00133-3DOI Listing
April 2003

In vivo imaging reveals estrogen receptor's hidden personality.

Nat Med 2003 Jan;9(1):22-3

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http://dx.doi.org/10.1038/nm0103-22DOI Listing
January 2003

Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism.

Nat Struct Biol 2002 May;9(5):359-64

The Howard Hughes Medical Institute and Department of Biochemistry and Biophysics, University of California, San Francisco, California 94143, USA.

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http://www.nature.com/doifinder/10.1038/nsb787
Publisher Site
http://dx.doi.org/10.1038/nsb787DOI Listing
May 2002