Gene G Olinger

Gene G Olinger

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Gene G Olinger

Gene G Olinger

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Nonhuman Primate Models of Ebola Virus Disease.

Curr Top Microbiol Immunol 2017;411:171-193

Integrated Research Facility, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Frederick, MD, USA.

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http://dx.doi.org/10.1007/82_2017_20DOI Listing
May 2019

Avian Influenza Is a Catalyst for Economic and Political Destabilization in Iran.

Health Secur 2018 Mar/Apr;16(2):143. Epub 2018 Mar 15.

Gene G. Olinger, PhD, MBA, is Principal Science Advisor, and Kenneth B. Yeh, MS, is Senior Science Advisor; both at MRIGlobal, Gaithersburg, Maryland.

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http://dx.doi.org/10.1089/hs.2018.0016DOI Listing
October 2018

Testing therapeutics in cell-based assays: Factors that influence the apparent potency of drugs.

PLoS One 2018 22;13(3):e0194880. Epub 2018 Mar 22.

Integrated Research Facility, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Frederick, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0194880PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864066PMC
July 2018

Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome: Current Therapeutic Options and Potential Targets for Novel Therapies.

Drugs 2017 Dec;77(18):1935-1966

Integrated Research Facility, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Frederick, MD, USA.

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http://dx.doi.org/10.1007/s40265-017-0830-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733787PMC
December 2017

High dose sertraline monotherapy fails to protect rhesus macaques from lethal challenge with Ebola virus Makona.

Sci Rep 2017 07 19;7(1):5886. Epub 2017 Jul 19.

Integrated Research Facility, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Frederick, 21702, Maryland, USA.

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http://dx.doi.org/10.1038/s41598-017-06179-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517626PMC
July 2017

Antibody therapeutics for Ebola virus disease.

Curr Opin Virol 2016 04 27;17:45-49. Epub 2016 Jan 27.

Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, 1015 Arlington Street, Winnipeg, Manitoba R3E 3R2, Canada; Department of Medical Microbiology, University of Manitoba, 745 Bannatyne Avenue, Winnipeg, Manitoba R3E 0J9, Canada; Department of Immunology, University of Manitoba, 745 Bannatyne Avenue, Winnipeg, Manitoba R3E 0J9, Canada.

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http://dx.doi.org/10.1016/j.coviro.2016.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902774PMC
April 2016

Viral Hemorrhagic Fever Diagnostics.

Clin Infect Dis 2016 Jan 9;62(2):214-9. Epub 2015 Sep 9.

Division of Clinical Research, National Institute of Allergy and Infectious Diseases, Integrated Research Facility, Frederick, Maryland.

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http://dx.doi.org/10.1093/cid/civ792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723665PMC
January 2016

The lipid moiety of brincidofovir is required for in vitro antiviral activity against Ebola virus.

Antiviral Res 2016 Jan 23;125:71-8. Epub 2015 Oct 23.

Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2015.10.010DOI Listing
January 2016

Inhibition of Ebola and Marburg Virus Entry by G Protein-Coupled Receptor Antagonists.

J Virol 2015 Oct 22;89(19):9932-8. Epub 2015 Jul 22.

Department of Microbiology and Immunology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA

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http://dx.doi.org/10.1128/JVI.01337-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577884PMC
October 2015

Fighting Ebola with novel spore decontamination technologies for the military.

Front Microbiol 2015 12;6:663. Epub 2015 Aug 12.

Children's Hospital - Oakland Research Institute, University of California San Francisco - Benioff, Oakland, CA USA.

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http://dx.doi.org/10.3389/fmicb.2015.00663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533522PMC
August 2015

Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs.

PLoS Pathog 2015 Jun 26;11(6):e1005016. Epub 2015 Jun 26.

Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America; Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1005016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482612PMC
June 2015

Antiviral potential of ERK/MAPK and PI3K/AKT/mTOR signaling modulation for Middle East respiratory syndrome coronavirus infection as identified by temporal kinome analysis.

Antimicrob Agents Chemother 2015 Feb 8;59(2):1088-99. Epub 2014 Dec 8.

Integrated Research Facility, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Frederick, Maryland, USA Emerging Viral Pathogens Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Frederick, Maryland, USA.

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http://aac.asm.org/content/59/2/1088.full.pdf
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http://aac.asm.org/content/early/2014/12/02/AAC.03659-14.ful
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http://aac.asm.org/lookup/doi/10.1128/AAC.03659-14
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http://dx.doi.org/10.1128/AAC.03659-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335870PMC
February 2015

The cyanobacterial lectin scytovirin displays potent in vitro and in vivo activity against Zaire Ebola virus.

Antiviral Res 2014 Dec 5;112:1-7. Epub 2014 Oct 5.

Molecular Targets Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, United States. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2014.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258435PMC
December 2014

Structures of protective antibodies reveal sites of vulnerability on Ebola virus.

Proc Natl Acad Sci U S A 2014 Dec 17;111(48):17182-7. Epub 2014 Nov 17.

Department of Immunology and Microbial Science, and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037;

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http://dx.doi.org/10.1073/pnas.1414164111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260551PMC
December 2014

Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp.

Nature 2014 Oct 29;514(7520):47-53. Epub 2014 Aug 29.

1] National Laboratory for Zoonotic Diseases and Special Pathogens, Public Health Agency of Canada, Winnipeg, Manitoba R3E 3R2, Canada [2] Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba R3E 0J9, Canada [3] Department of Immunology, University of Manitoba, Winnipeg, Manitoba R3E 0T5, Canada [4] Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/nature13777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214273PMC
October 2014

Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names.

Viruses 2014 Sep 26;6(9):3663-82. Epub 2014 Sep 26.

IViral Special Pathogens Branch, Division of High-Consequence Pathogens Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.

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http://dx.doi.org/10.3390/v6093663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189044PMC
September 2014

Post-exposure therapy of filovirus infections.

Trends Microbiol 2014 Aug 30;22(8):456-63. Epub 2014 Apr 30.

Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada; Department of Medical Microbiology, University of Manitoba, Winnipeg, MB, Canada; Department of Immunology, University of Manitoba, Winnipeg, MB, Canada; Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0966842X140007
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http://dx.doi.org/10.1016/j.tim.2014.04.002DOI Listing
August 2014

Pyridinyl imidazole inhibitors of p38 MAP kinase impair viral entry and reduce cytokine induction by Zaire ebolavirus in human dendritic cells.

Antiviral Res 2014 Jul 9;107:102-9. Epub 2014 May 9.

Dept. of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2014.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103912PMC
July 2014

Comparison of the plaque assay and 50% tissue culture infectious dose assay as methods for measuring filovirus infectivity.

J Virol Methods 2013 Nov 5;193(2):565-71. Epub 2013 Jun 5.

Biomedical Sciences Department, Defence Science and Technology Laboratory (DSTL), Porton Down, Salisbury, Wiltshire SP4 0JQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jviromet.2013.05.015DOI Listing
November 2013

Standardization of the filovirus plaque assay for use in preclinical studies.

Viruses 2012 Dec 6;4(12):3511-30. Epub 2012 Dec 6.

Integrated Toxicology Division, United States Army Medical Research Institute of Infectious Diseases, 1425 Porter Street, Frederick, MD 21702, USA.

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http://dx.doi.org/10.3390/v4123511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528277PMC
December 2012

Potential vaccines and post-exposure treatments for filovirus infections.

Viruses 2012 Sep 21;4(9):1619-50. Epub 2012 Sep 21.

United States Army Medical Research Institute of Infectious Diseases, Division of Virology, Frederick, MD 21702, USA.

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http://dx.doi.org/10.3390/v4091619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499823PMC
September 2012

Real-time monitoring of cardiovascular function in rhesus macaques infected with Zaire ebolavirus.

J Infect Dis 2011 Nov;204 Suppl 3:S1000-10

Department of Preventive Medicine, Infectious Disease Clinical Research Program, Uniformed Services University, Bethesda, MD 20814, USA.

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https://academic.oup.com/jid/article-lookup/doi/10.1093/infd
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http://dx.doi.org/10.1093/infdis/jir337DOI Listing
November 2011

High-dose mannose-binding lectin therapy for Ebola virus infection.

J Infect Dis 2011 Jan;203(2):175-9

Program of Developmental Immunology, Department of Pediatrics, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1093/infdis/jiq025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071052PMC
January 2011

Zaire Ebola virus entry into human dendritic cells is insensitive to cathepsin L inhibition.

Cell Microbiol 2010 Feb 22;12(2):148-57. Epub 2009 Sep 22.

Department of Microbiology, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1111/j.1462-5822.2009.01385.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996272PMC
February 2010

Discovery of common marburgvirus protective epitopes in a BALB/c mouse model.

Virol J 2009 Aug 27;6:132. Epub 2009 Aug 27.

Division of Bacteriology, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Fort Detrick, Maryland, 21702, USA.

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http://dx.doi.org/10.1186/1743-422X-6-132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746211PMC
August 2009

Donor variability in HIV binding to peripheral blood mononuclear cells.

Virol J 2008 Aug 15;5:95. Epub 2008 Aug 15.

Section of Experimental Atherosclerosis, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Drive, Building 10, Room 5N111, Bethesda, Maryland 20892, USA.

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http://virologyj.biomedcentral.com/articles/10.1186/1743-422
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http://dx.doi.org/10.1186/1743-422X-5-95DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2538508PMC
August 2008

Ebola virus-like particle-based vaccine protects nonhuman primates against lethal Ebola virus challenge.

J Infect Dis 2007 Nov;196 Suppl 2:S430-7

US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702, USA.

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http://dx.doi.org/10.1086/520583DOI Listing
November 2007

Filoviruses and the balance of innate, adaptive, and inflammatory responses.

Viral Immunol 2006 ;19(4):602-12

US Army Medical Research Institute for Infectious Diseases, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1089/vim.2006.19.602DOI Listing
February 2007

Mannose-binding lectin binds to Ebola and Marburg envelope glycoproteins, resulting in blocking of virus interaction with DC-SIGN and complement-mediated virus neutralization.

J Gen Virol 2005 Sep;86(Pt 9):2535-42

Rush St Luke's Medical Center, Department of Immunology and Microbiology, 1653 W. Congress Parkway, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1099/vir.0.81199-0DOI Listing
September 2005

Cellular factors influence the binding of HIV type 1 to cells.

AIDS Res Hum Retroviruses 2002 Mar;18(4):259-67

Department of Immunology/Microbiology, Rush University, Chicago, Illinois 60612, USA.

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http://dx.doi.org/10.1089/088922202753472838DOI Listing
March 2002