Publications by authors named "Gemma Fabriàs"

99Publications

β-Galactosylceramidase Promotes Melanoma Growth via Modulation of Ceramide Metabolism.

Authors:
Mirella Belleri Giuseppe Paganini Daniela Coltrini Roberto Ronca Daniela Zizioli Michela Corsini Andrea Barbieri Elisabetta Grillo Stefano Calza Roberto Bresciani Eugenio Maiorano Mauro G Mastropasqua Tiziana Annese Arianna Giacomini Domenico Ribatti Josefina Casas Thierry Levade Gemma Fabrias Marco Presta

Cancer Res 2020 Nov 30;80(22):5011-5023. Epub 2020 Sep 30.

Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.

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November 2020

CCR5 deficiency impairs CD4 T-cell memory responses and antigenic sensitivity through increased ceramide synthesis.

Authors:
Ana Martín-Leal Raquel Blanco Josefina Casas María E Sáez Elena Rodríguez-Bovolenta Itziar de Rojas Carina Drechsler Luis Miguel Real Gemma Fabrias Agustín Ruíz Mario Castro Wolfgang Wa Schamel Balbino Alarcón Hisse M van Santen Santos Mañes

EMBO J 2020 Aug 11;39(15):e104749. Epub 2020 Jun 11.

Department of Immunology and Oncology, Centro Nacional de Biotecnología (CNB/CSIC), Madrid, Spain.

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August 2020

The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells.

Authors:
Pau Muñoz-Guardiola Josefina Casas Elisabet Megías-Roda Sònia Solé Héctor Perez-Montoyo Marc Yeste-Velasco Tatiana Erazo Nora Diéguez-Martínez Sergio Espinosa-Gil Cristina Muñoz-Pinedo Guillermo Yoldi Jose L Abad Miguel F Segura Teresa Moran Margarita Romeo Joaquim Bosch-Barrera Ana Oaknin Jose Alfón Carles Domènech Gemma Fabriàs Guillermo Velasco Jose M Lizcano

Autophagy 2020 May 25:1-18. Epub 2020 May 25.

Protein Kinases and Signal Transduction Laboratory, Departament De Bioquímica I Biologia Molecular and Institut De Neurociències, Universitat Autònoma De Barcelona (UAB) , Barcelona, Spain.

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May 2020

Ovarian Hormone-Dependent Effects of Dietary Lipids on APP/PS1 Mouse Brain.

Authors:
Jose Luis Herrera Lara Ordoñez-Gutierrez Gemma Fabrias Josefina Casas Araceli Morales Guadalberto Hernandez Nieves G Acosta Covadonga Rodriguez Luis Prieto-Valiente Luis M Garcia-Segura Francisco G Wandosell Rafael Alonso

Front Aging Neurosci 2019 19;11:346. Epub 2019 Dec 19.

Departamento de Ciencias Médicas Básicas, Instituto de Tecnologías Biomédicas-Centro de Investigaciones Biomédicas de Canarias, Universidad de La Laguna, San Cristóbal de La Laguna, Spain.

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December 2019

A Mechanism-Based Sphingosine-1-phosphate Lyase Inhibitor.

Authors:
Guillem Pons Daniel Riba Mireia Casasampere Eduardo Izquierdo José-Luís Abad Gemma Fabriàs Pilar G Rodríguez Ortega Juan J López-González Manuel Montejo Josefina Casas Antonio Delgado

J Org Chem 2020 01 3;85(2):419-429. Epub 2020 Jan 3.

Spanish National Research Council (CSIC), Institute for Advanced Chemistry of Catalonia (IQAC-CSIC) , Research Unit on Bioactive Molecules (RUBAM), Department of Biological Chemistry , Jordi Girona 18-26 , 08034 Barcelona , Spain.

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January 2020

Ceramide Analogue SACLAC Modulates Sphingolipid Levels and Splicing to Induce Apoptosis in Acute Myeloid Leukemia.

Authors:
Jennifer M Pearson Su-Fern Tan Arati Sharma Charyguly Annageldiyev Todd E Fox Jose Luis Abad Gemma Fabrias Dhimant Desai Shantu Amin Hong-Gang Wang Myles C Cabot David F Claxton Mark Kester David J Feith Thomas P Loughran

Mol Cancer Res 2020 03 19;18(3):352-363. Epub 2019 Nov 19.

Department of Medicine, Division of Hematology & Oncology, University of Virginia, Charlottesville, Virginia.

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March 2020

Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells.

Authors:
Li-Pin Kao Samy A F Morad Traci S Davis Matthew R MacDougall Miki Kassai Noha Abdelmageed Todd E Fox Mark Kester Thomas P Loughran Jose' L Abad Gemma Fabrias Su-Fern Tan David J Feith David F Claxton Sarah Spiegel Kelsey H Fisher-Wellman Myles C Cabot

J Lipid Res 2019 09 30;60(9):1590-1602. Epub 2019 Jul 30.

Department of Biochemistry and Molecular Biology Brody School of Medicine, East Carolina University, and the East Carolina Diabetes and Obesity Institute, Greenville, NC

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September 2019

Activity-Based Imaging of Acid Ceramidase in Living Cells.

Authors:
Yadira F Ordóñez José Luís Abad Mazen Aseeri Josefina Casas Virginie Garcia Mireia Casasampere Edward H Schuchman Thierry Levade Antonio Delgado Gemma Triola Gemma Fabrias

J Am Chem Soc 2019 05 2;141(19):7736-7742. Epub 2019 May 2.

Research Unit on Bioactive Molecules (RUBAM), Department of Biological Chemistry , Institute for Advanced Chemistry of Catalonia (IQAC-CSIC) , Jordi Girona, 18 , 08034 Barcelona , Spain.

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May 2019

New fluorogenic probes for neutral and alkaline ceramidases.

Authors:
Mireia Casasampere Núria Bielsa Daniel Riba Laura Bassas Ruijuan Xu Cungui Mao Gemma Fabriàs José-Luis Abad Antonio Delgado Josefina Casas

J Lipid Res 2019 06 29;60(6):1174-1181. Epub 2019 Mar 29.

Spanish National Research Council (CSIC), Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Department of Biological Chemistry, Research Unit on Bioactive Molecules (RUBAM), 08034 Barcelona, Spain

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June 2019

Clearly Detectable, Kinetically Restricted Solid-Solid Phase Transition in cis-Ceramide Monolayers.

Authors:
M Laura Fanani Jon V Busto Jesús Sot José L Abad Gemma Fabrías Leonor Saiz Jose M G Vilar Félix M Goñi Bruno Maggio Alicia Alonso

Langmuir 2018 10 24;34(39):11749-11758. Epub 2018 Sep 24.

Instituto Biofisika (CSIC, UPV/EHU) , B. Sarriena s/n , 48940 Leioa , Spain.

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October 2018

Ovarian Function Modulates the Effects of Long-Chain Polyunsaturated Fatty Acids on the Mouse Cerebral Cortex.

Authors:
Jose L Herrera Lara Ordoñez-Gutierrez Gemma Fabrias Josefina Casas Araceli Morales Guadalberto Hernandez Nieves G Acosta Covadonga Rodriguez Luis Prieto-Valiente Luis M Garcia-Segura Rafael Alonso Francisco G Wandosell

Front Cell Neurosci 2018 24;12:103. Epub 2018 Apr 24.

Centro de Biología Molecular "Severo Ochoa" (CSIC-UAM), Universidad Autónoma de Madrid, Madrid, Spain.

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April 2018

SOD3 improves the tumor response to chemotherapy by stabilizing endothelial HIF-2α.

Authors:
Emilia Mira Lorena Carmona-Rodríguez Beatriz Pérez-Villamil Josefina Casas María Jesús Fernández-Aceñero Diego Martínez-Rey Paula Martín-González Ignacio Heras-Murillo Mateo Paz-Cabezas Manuel Tardáguila Tim D Oury Silvia Martín-Puig Rosa Ana Lacalle Gemma Fabriás Eduardo Díaz-Rubio Santos Mañes

Nat Commun 2018 02 8;9(1):575. Epub 2018 Feb 8.

Department of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Darwin, 3, Madrid, 28049, Spain.

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February 2018

Dihydroceramide Desaturase 1 Inhibitors Reduce Amyloid-β Levels in Primary Neurons from an Alzheimer's Disease Transgenic Model.

Authors:
Lara Ordóñez-Gutiérrez Irene Benito-Cuesta José Luis Abad Josefina Casas Gemma Fábrias Francisco Wandosell

Pharm Res 2018 Feb 6;35(3):49. Epub 2018 Feb 6.

Centro de Biología Molecular "Severo Ochoa" CSIC-UAM, Nicolás Cabrera, 1, Madrid, Spain.

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February 2018

Ghrelin Causes a Decline in GABA Release by Reducing Fatty Acid Oxidation in Cortex.

Authors:
Joan Francesc Mir Sebastián Zagmutt Mathieu P Lichtenstein Judit García-Villoria Minéia Weber Ana Gracia Gemma Fabriàs Josefina Casas Miguel López Núria Casals Antònia Ribes Cristina Suñol Laura Herrero Dolors Serra

Mol Neurobiol 2018 Sep 2;55(9):7216-7228. Epub 2018 Feb 2.

Department of Biochemistry and Physiology, Facultat de Farmàcia i Ciències de l'Alimentació and Institut de Biomedicina de la Universitat de Barcelona (IBUB), Universitat de Barcelona, Av. Joan XXIII, 27-30, E-08028, Barcelona, Spain.

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September 2018

Jaspine B induces nonapoptotic cell death in gastric cancer cells independently of its inhibition of ceramide synthase.

Authors:
Francesca Cingolani Fabio Simbari Jose Luis Abad Mireia Casasampere Gemma Fabrias Anthony H Futerman Josefina Casas

J Lipid Res 2017 08 1;58(8):1500-1513. Epub 2017 Jun 1.

Research Unit on BioActive Molecules (RUBAM), Department of Biomedicinal Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona, Spain

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August 2017

The first fluorogenic sensor for sphingosine-1-phosphate lyase activity in intact cells.

Authors:
Pol Sanllehí Mireia Casasampere José-Luis Abad Gemma Fabriàs Olga López Jordi Bujons Josefina Casas Antonio Delgado

Chem Commun (Camb) 2017 May;53(39):5441-5444

Spanish National Research Council (CSIC), Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), Research Unit on Bioactive Molecules (RUBAM), Department of Biomedicinal Chemistry, Jordi Girona 18 26, 08034 Barcelona, Spain.

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May 2017

Stereoselective preparation of quaternary 2-vinyl sphingosines and ceramides and their effect on basal sphingolipid metabolism.

Authors:
Raquel Calderón Nerea Mercadal José Luis Abad Xavier Ariza Antonio Delgado Jordi Garcia Aleix Rodríguez Gemma Fabriàs

Chem Phys Lipids 2017 06 23;205:34-41. Epub 2017 Apr 23.

Consejo Superior de Investigaciones Científicas (CSIC), Institut de Química Avançada de Catalunya (IQAC-CSIC), Research Unit on Bioactive Molecules (RUBAM), Calle Jordi Girona 18-26, 08034 Barcelona, Spain. Electronic address:

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June 2017

From the configurational preference of dihydroceramide desaturase-1 towards Δ-unsaturated substrates to the discovery of a new inhibitor.

Authors:
Ana Pou José-Luís Abad Yadira F Ordóñez Maria Garrido Josefina Casas Gemma Fabriàs Antonio Delgado

Chem Commun (Camb) 2017 Apr;53(31):4394-4397

Spanish National Research Council (CSIC), Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), Research Unit on Bioactive Molecules (RUBAM), Department of Biomedicinal Chemistry, Jordi Girona 18-26, 08034-Barcelona, Spain.

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April 2017

Acid Ceramidase Deficiency in Mice Results in a Broad Range of Central Nervous System Abnormalities.

Authors:
Jakub Sikora Shaalee Dworski E Ellen Jones Mustafa A Kamani Matthew C Micsenyi Tomo Sawada Pauline Le Faouder Justine Bertrand-Michel Aude Dupuy Christopher K Dunn Ingrid Cong Yang Xuan Josefina Casas Gemma Fabrias David R Hampson Thierry Levade Richard R Drake Jeffrey A Medin Steven U Walkley

Am J Pathol 2017 Apr;187(4):864-883

Dominick P. Purpura Department of Neuroscience, Rose F. Kennedy Intellectual and Developmental Disabilities Research Center, Albert Einstein College of Medicine, Bronx, New York. Electronic address:

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April 2017

Corrigendum to "Sphingolipids as Mediators in the Crosstalk between Microbiota and Intestinal Cells: Implications for Inflammatory Bowel Disease".

Authors:
Bryan Phillips-Farfán Karla Carvajal Edgar Alejandro Medina-Torres Sara Elva Espinosa-Padilla Gemma Fabrias Luz Camacho

Mediators Inflamm 2016;2016:7267956. Epub 2016 Nov 14.

Laboratorio de Nutrición Experimental, Instituto Nacional de Pediatría, 04530 Ciudad de México, Mexico.

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November 2016

Dihydroceramide desaturase inhibitors induce autophagy via dihydroceramide-dependent and independent mechanisms.

Authors:
Mireia Casasampere Yadira F Ordóñez Josefina Casas Gemma Fabrias

Biochim Biophys Acta Gen Subj 2017 Feb 25;1861(2):264-275. Epub 2016 Nov 25.

Consejo Superior de Investigaciones Científicas (CSIC), Institut de Química Avançada de Catalunya (IQAC-CSIC), Departament de Química Biomèdica, Research Unit on Bioactive Molecules (RUBAM), Jordi Girona 18-26, 08034 Barcelona, Spain.. Electronic address:

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February 2017

Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease.

Authors:
Sandra Torres Nuria Matías Anna Baulies Susana Nuñez Cristina Alarcon-Vila Laura Martinez Natalia Nuño Anna Fernandez Joan Caballeria Thierry Levade Alba Gonzalez-Franquesa Pablo Garcia-Rovés Elisa Balboa Silvana Zanlungo Gemma Fabrías Josefina Casas Carlos Enrich Carmen Garcia-Ruiz José C Fernández-Checa

Redox Biol 2017 04 20;11:60-72. Epub 2016 Nov 20.

Cell Death and Proliferation, Institute of Biomedical Research of Barcelona (IIBB), CSIC, Barcelona, Spain; Liver Unit, Hospital Clinic I Provincial de Barcelona, IDIBAPS and CIBERehd, Barcelona, Spain; Research Center for ALPD, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States. Electronic address:

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April 2017

Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization.

Authors:
Sonia Hernández-Tiedra Gemma Fabriàs David Dávila Íñigo J Salanueva Josefina Casas L Ruth Montes Zuriñe Antón Elena García-Taboada María Salazar-Roa Mar Lorente Jesper Nylandsted Jane Armstrong Israel López-Valero Christopher S McKee Ana Serrano-Puebla Roberto García-López José González-Martínez José L Abad Kentaro Hanada Patricia Boya Félix Goñi Manuel Guzmán Penny Lovat Marja Jäättelä Alicia Alonso Guillermo Velasco

Autophagy 2016 11 16;12(11):2213-2229. Epub 2016 Sep 16.

a Department of Biochemistry and Molecular Biology I , School of Biology, Complutense University , Madrid , Spain.

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November 2016

Sphingolipids as Mediators in the Crosstalk between Microbiota and Intestinal Cells: Implications for Inflammatory Bowel Disease.

Authors:
Phillips-Farfán Bryan Carvajal Karla Medina-Torres Edgar Alejandro Espinosa-Padilla Sara Elva Fabrias Gemma Camacho Luz

Mediators Inflamm 2016;2016:9890141. Epub 2016 Aug 30.

Laboratorio de Nutrición Experimental, Instituto Nacional de Pediatría, 04530 Ciudad de México, Mexico.

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August 2016

Plasmalogen enrichment in exosomes secreted by a nematode parasite versus those derived from its mouse host: implications for exosome stability and biology.

Authors:
Fabio Simbari Jana McCaskill Gillian Coakley Marissa Millar Rick M Maizels Gemma Fabriás Josefina Casas Amy H Buck

J Extracell Vesicles 2016 5;5:30741. Epub 2016 Jul 5.

Institute of Immunology and Infection Research and Centre for Immunity, Infection and Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh, UK;

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July 2016

3-Ketosphinganine provokes the accumulation of dihydroshingolipids and induces autophagy in cancer cells.

Authors:
Yadira F Ordóñez Jèssica González Carmen Bedia Josefina Casas José Luis Abad Antonio Delgado Gemma Fabrias

Mol Biosyst 2016 Apr 1;12(4):1166-73. Epub 2016 Mar 1.

Consejo Superior de Investigaciones Científicas (CSIC), Institut de Química Avançada de Catalunya (IQAC-CSIC), Research Unit on Bioactive Molecules (RUBAM), Jordi Girona 18-26, 08034 Barcelona, Spain.

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April 2016

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Authors:
Daniel J Klionsky Kotb Abdelmohsen Akihisa Abe Md Joynal Abedin Hagai Abeliovich Abraham Acevedo Arozena Hiroaki Adachi Christopher M Adams Peter D Adams Khosrow Adeli Peter J Adhihetty Sharon G Adler Galila Agam Rajesh Agarwal Manish K Aghi Maria Agnello Patrizia Agostinis Patricia V Aguilar Julio Aguirre-Ghiso Edoardo M Airoldi Slimane Ait-Si-Ali Takahiko Akematsu Emmanuel T Akporiaye Mohamed Al-Rubeai Guillermo M Albaiceta Chris Albanese Diego Albani Matthew L Albert Jesus Aldudo Hana Algül Mehrdad Alirezaei Iraide Alloza Alexandru Almasan Maylin Almonte-Beceril Emad S Alnemri Covadonga Alonso Nihal Altan-Bonnet Dario C Altieri Silvia Alvarez Lydia Alvarez-Erviti Sandro Alves Giuseppina Amadoro Atsuo Amano Consuelo Amantini Santiago Ambrosio Ivano Amelio Amal O Amer Mohamed Amessou Angelika Amon Zhenyi An Frank A Anania Stig U Andersen Usha P Andley Catherine K Andreadi Nathalie Andrieu-Abadie Alberto Anel David K Ann Shailendra Anoopkumar-Dukie Manuela Antonioli Hiroshi Aoki Nadezda Apostolova Saveria Aquila Katia Aquilano Koichi Araki Eli Arama Agustin Aranda Jun Araya Alexandre Arcaro Esperanza Arias Hirokazu Arimoto Aileen R Ariosa Jane L Armstrong Thierry Arnould Ivica Arsov Katsuhiko Asanuma Valerie Askanas Eric Asselin Ryuichiro Atarashi Sally S Atherton Julie D Atkin Laura D Attardi Patrick Auberger Georg Auburger Laure Aurelian Riccardo Autelli Laura Avagliano Maria Laura Avantaggiati Limor Avrahami Suresh Awale Neelam Azad Tiziana Bachetti Jonathan M Backer Dong-Hun Bae Jae-Sung Bae Ok-Nam Bae Soo Han Bae Eric H Baehrecke Seung-Hoon Baek Stephen Baghdiguian Agnieszka Bagniewska-Zadworna Hua Bai Jie Bai Xue-Yuan Bai Yannick Bailly Kithiganahalli Narayanaswamy Balaji Walter Balduini Andrea Ballabio Rena Balzan Rajkumar Banerjee Gábor Bánhegyi Haijun Bao Benoit Barbeau Maria D Barrachina Esther Barreiro Bonnie Bartel Alberto Bartolomé Diane C Bassham Maria Teresa Bassi Robert C Bast Alakananda Basu Maria Teresa Batista Henri Batoko Maurizio Battino Kyle Bauckman Bradley L Baumgarner K Ulrich Bayer Rupert Beale Jean-François Beaulieu George R Beck Christoph Becker J David Beckham Pierre-André Bédard Patrick J Bednarski Thomas J Begley Christian Behl Christian Behrends Georg Mn Behrens Kevin E Behrns Eloy Bejarano Amine Belaid Francesca Belleudi Giovanni Bénard Guy Berchem Daniele Bergamaschi Matteo Bergami Ben Berkhout Laura Berliocchi Amélie Bernard Monique Bernard Francesca Bernassola Anne Bertolotti Amanda S Bess Sébastien Besteiro Saverio Bettuzzi Savita Bhalla Shalmoli Bhattacharyya Sujit K Bhutia Caroline Biagosch Michele Wolfe Bianchi Martine Biard-Piechaczyk Viktor Billes Claudia Bincoletto Baris Bingol Sara W Bird Marc Bitoun Ivana Bjedov Craig Blackstone Lionel Blanc Guillermo A Blanco Heidi Kiil Blomhoff Emilio Boada-Romero Stefan Böckler Marianne Boes Kathleen Boesze-Battaglia Lawrence H Boise Alessandra Bolino Andrea Boman Paolo Bonaldo Matteo Bordi Jürgen Bosch Luis M Botana Joelle Botti German Bou Marina Bouché Marion Bouchecareilh Marie-Josée Boucher Michael E Boulton Sebastien G Bouret Patricia Boya Michaël Boyer-Guittaut Peter V Bozhkov Nathan Brady Vania Mm Braga Claudio Brancolini Gerhard H Braus José M Bravo-San Pedro Lisa A Brennan Emery H Bresnick Patrick Brest Dave Bridges Marie-Agnès Bringer Marisa Brini Glauber C Brito Bertha Brodin Paul S Brookes Eric J Brown Karen Brown Hal E Broxmeyer Alain Bruhat Patricia Chakur Brum John H Brumell Nicola Brunetti-Pierri Robert J Bryson-Richardson Shilpa Buch Alastair M Buchan Hikmet Budak Dmitry V Bulavin Scott J Bultman Geert Bultynck Vladimir Bumbasirevic Yan Burelle Robert E Burke Margit Burmeister Peter Bütikofer Laura Caberlotto Ken Cadwell Monika Cahova Dongsheng Cai Jingjing Cai Qian Cai Sara Calatayud Nadine Camougrand Michelangelo Campanella Grant R Campbell Matthew Campbell Silvia Campello Robin Candau Isabella Caniggia Lavinia Cantoni Lizhi Cao Allan B Caplan Michele Caraglia Claudio Cardinali Sandra Morais Cardoso Jennifer S Carew Laura A Carleton Cathleen R Carlin Silvia Carloni Sven R Carlsson Didac Carmona-Gutierrez Leticia Am Carneiro Oliana Carnevali Serena Carra Alice Carrier Bernadette Carroll Caty Casas Josefina Casas Giuliana Cassinelli Perrine Castets Susana Castro-Obregon Gabriella Cavallini Isabella Ceccherini Francesco Cecconi Arthur I Cederbaum Valentín Ceña Simone Cenci Claudia Cerella Davide Cervia Silvia Cetrullo Hassan Chaachouay Han-Jung Chae Andrei S Chagin Chee-Yin Chai Gopal Chakrabarti Georgios Chamilos Edmond Yw Chan Matthew Tv Chan Dhyan Chandra Pallavi Chandra Chih-Peng Chang Raymond Chuen-Chung Chang Ta Yuan Chang John C Chatham Saurabh Chatterjee Santosh Chauhan Yongsheng Che Michael E Cheetham Rajkumar Cheluvappa Chun-Jung Chen Gang Chen Guang-Chao Chen Guoqiang Chen Hongzhuan Chen Jeff W Chen Jian-Kang Chen Min Chen Mingzhou Chen Peiwen Chen Qi Chen Quan Chen Shang-Der Chen Si Chen Steve S-L Chen Wei Chen Wei-Jung Chen Wen Qiang Chen Wenli Chen Xiangmei Chen Yau-Hung Chen Ye-Guang Chen Yin Chen Yingyu Chen Yongshun Chen Yu-Jen Chen Yue-Qin Chen Yujie Chen Zhen Chen Zhong Chen Alan Cheng Christopher Hk Cheng Hua Cheng Heesun Cheong Sara Cherry Jason Chesney Chun Hei Antonio Cheung Eric Chevet Hsiang Cheng Chi Sung-Gil Chi Fulvio Chiacchiera Hui-Ling Chiang Roberto Chiarelli Mario Chiariello Marcello Chieppa Lih-Shen Chin Mario Chiong Gigi Nc Chiu Dong-Hyung Cho Ssang-Goo Cho William C Cho Yong-Yeon Cho Young-Seok Cho Augustine Mk Choi Eui-Ju Choi Eun-Kyoung Choi Jayoung Choi Mary E Choi Seung-Il Choi Tsui-Fen Chou Salem Chouaib Divaker Choubey Vinay Choubey Kuan-Chih Chow Kamal Chowdhury Charleen T Chu Tsung-Hsien Chuang Taehoon Chun Hyewon Chung Taijoon Chung Yuen-Li Chung Yong-Joon Chwae Valentina Cianfanelli Roberto Ciarcia Iwona A Ciechomska Maria Rosa Ciriolo Mara Cirone Sofie Claerhout Michael J Clague Joan Clària Peter Gh Clarke Robert Clarke Emilio Clementi Cédric Cleyrat Miriam Cnop Eliana M Coccia Tiziana Cocco Patrice Codogno Jörn Coers Ezra Ew Cohen David Colecchia Luisa Coletto Núria S Coll Emma Colucci-Guyon Sergio Comincini Maria Condello Katherine L Cook Graham H Coombs Cynthia D Cooper J Mark Cooper Isabelle Coppens Maria Tiziana Corasaniti Marco Corazzari Ramon Corbalan Elisabeth Corcelle-Termeau Mario D Cordero Cristina Corral-Ramos Olga Corti Andrea Cossarizza Paola Costelli Safia Costes Susan L Cotman Ana Coto-Montes Sandra Cottet Eduardo Couve Lori R Covey L Ashley Cowart Jeffery S Cox Fraser P Coxon Carolyn B Coyne Mark S Cragg Rolf J Craven Tiziana Crepaldi Jose L Crespo Alfredo Criollo Valeria Crippa Maria Teresa Cruz Ana Maria Cuervo Jose M Cuezva Taixing Cui Pedro R Cutillas Mark J Czaja Maria F Czyzyk-Krzeska Ruben K Dagda Uta Dahmen Chunsun Dai Wenjie Dai Yun Dai Kevin N Dalby Luisa Dalla Valle Guillaume Dalmasso Marcello D'Amelio Markus Damme Arlette Darfeuille-Michaud Catherine Dargemont Victor M Darley-Usmar Srinivasan Dasarathy Biplab Dasgupta Srikanta Dash Crispin R Dass Hazel Marie Davey Lester M Davids David Dávila Roger J Davis Ted M Dawson Valina L Dawson Paula Daza Jackie de Belleroche Paul de Figueiredo Regina Celia Bressan Queiroz de Figueiredo José de la Fuente Luisa De Martino Antonella De Matteis Guido Ry De Meyer Angelo De Milito Mauro De Santi Wanderley de Souza Vincenzo De Tata Daniela De Zio Jayanta Debnath Reinhard Dechant Jean-Paul Decuypere Shane Deegan Benjamin Dehay Barbara Del Bello Dominic P Del Re Régis Delage-Mourroux Lea Md Delbridge Louise Deldicque Elizabeth Delorme-Axford Yizhen Deng Joern Dengjel Melanie Denizot Paul Dent Channing J Der Vojo Deretic Benoît Derrien Eric Deutsch Timothy P Devarenne Rodney J Devenish Sabrina Di Bartolomeo Nicola Di Daniele Fabio Di Domenico Alessia Di Nardo Simone Di Paola Antonio Di Pietro Livia Di Renzo Aaron DiAntonio Guillermo Díaz-Araya Ines Díaz-Laviada Maria T Diaz-Meco Javier Diaz-Nido Chad A Dickey Robert C Dickson Marc Diederich Paul Digard Ivan Dikic Savithrama P Dinesh-Kumar Chan Ding Wen-Xing Ding Zufeng Ding Luciana Dini Jörg Hw Distler Abhinav Diwan Mojgan Djavaheri-Mergny Kostyantyn Dmytruk Renwick Cj Dobson Volker Doetsch Karol Dokladny Svetlana Dokudovskaya Massimo Donadelli X Charlie Dong Xiaonan Dong Zheng Dong Terrence M Donohue Kelly S Doran Gabriella D'Orazi Gerald W Dorn Victor Dosenko Sami Dridi Liat Drucker Jie Du Li-Lin Du Lihuan Du André du Toit Priyamvada Dua Lei Duan Pu Duann Vikash Kumar Dubey Michael R Duchen Michel A Duchosal Helene Duez Isabelle Dugail Verónica I Dumit Mara C Duncan Elaine A Dunlop William A Dunn Nicolas Dupont Luc Dupuis Raúl V Durán Thomas M Durcan Stéphane Duvezin-Caubet Umamaheswar Duvvuri Vinay Eapen Darius Ebrahimi-Fakhari Arnaud Echard Leopold Eckhart Charles L Edelstein Aimee L Edinger Ludwig Eichinger Tobias Eisenberg Avital Eisenberg-Lerner N Tony Eissa Wafik S El-Deiry Victoria El-Khoury Zvulun Elazar Hagit Eldar-Finkelman Chris Jh Elliott Enzo Emanuele Urban Emmenegger Nikolai Engedal Anna-Mart Engelbrecht Simone Engelender Jorrit M Enserink Ralf Erdmann Jekaterina Erenpreisa Rajaraman Eri Jason L Eriksen Andreja Erman Ricardo Escalante Eeva-Liisa Eskelinen Lucile Espert Lorena Esteban-Martínez Thomas J Evans Mario Fabri Gemma Fabrias Cinzia Fabrizi Antonio Facchiano Nils J Færgeman Alberto Faggioni W Douglas Fairlie Chunhai Fan Daping Fan Jie Fan Shengyun Fang Manolis Fanto Alessandro Fanzani Thomas Farkas Mathias Faure Francois B Favier Howard Fearnhead Massimo Federici Erkang Fei Tania C Felizardo Hua Feng Yibin Feng Yuchen Feng Thomas A Ferguson Álvaro F Fernández Maite G Fernandez-Barrena Jose C Fernandez-Checa Arsenio Fernández-López Martin E Fernandez-Zapico Olivier Feron Elisabetta Ferraro Carmen Veríssima Ferreira-Halder Laszlo Fesus Ralph Feuer Fabienne C Fiesel Eduardo C Filippi-Chiela Giuseppe Filomeni Gian Maria Fimia John H Fingert Steven Finkbeiner Toren Finkel Filomena Fiorito Paul B Fisher Marc Flajolet Flavio Flamigni Oliver Florey Salvatore Florio R Andres Floto Marco Folini Carlo Follo Edward A Fon Francesco Fornai Franco Fortunato Alessandro Fraldi Rodrigo Franco Arnaud Francois Aurélie François Lisa B Frankel Iain Dc Fraser Norbert Frey Damien G Freyssenet Christian Frezza Scott L Friedman Daniel E Frigo Dongxu Fu José M Fuentes Juan Fueyo Yoshio Fujitani Yuuki Fujiwara Mikihiro Fujiya Mitsunori Fukuda Simone Fulda Carmela Fusco Bozena Gabryel Matthias Gaestel Philippe Gailly Malgorzata Gajewska Sehamuddin Galadari Gad Galili Inmaculada Galindo Maria F Galindo Giovanna Galliciotti Lorenzo Galluzzi Luca Galluzzi Vincent Galy Noor Gammoh Sam Gandy Anand K Ganesan Swamynathan Ganesan Ian G Ganley Monique Gannagé Fen-Biao Gao Feng Gao Jian-Xin Gao Lorena García Nannig Eleonora García Véscovi Marina Garcia-Macía Carmen Garcia-Ruiz Abhishek D Garg Pramod Kumar Garg Ricardo Gargini Nils Christian Gassen Damián Gatica Evelina Gatti Julie Gavard Evripidis Gavathiotis Liang Ge Pengfei Ge Shengfang Ge Po-Wu Gean Vania Gelmetti Armando A Genazzani Jiefei Geng Pascal Genschik Lisa Gerner Jason E Gestwicki David A Gewirtz Saeid Ghavami Eric Ghigo Debabrata Ghosh Anna Maria Giammarioli Francesca Giampieri Claudia Giampietri Alexandra Giatromanolaki Derrick J Gibbings Lara Gibellini Spencer B Gibson Vanessa Ginet Antonio Giordano Flaviano Giorgini Elisa Giovannetti Stephen E Girardin Suzana Gispert Sandy Giuliano Candece L Gladson Alvaro Glavic Martin Gleave Nelly Godefroy Robert M Gogal Kuppan Gokulan Gustavo H Goldman Delia Goletti Michael S Goligorsky Aldrin V Gomes Ligia C Gomes Hernando Gomez Candelaria Gomez-Manzano Rubén Gómez-Sánchez Dawit Ap Gonçalves Ebru Goncu Qingqiu Gong Céline Gongora Carlos B Gonzalez Pedro Gonzalez-Alegre Pilar Gonzalez-Cabo Rosa Ana González-Polo Ing Swie Goping Carlos Gorbea Nikolai V Gorbunov Daphne R Goring Adrienne M Gorman Sharon M Gorski Sandro Goruppi Shino Goto-Yamada Cecilia Gotor Roberta A Gottlieb Illana Gozes Devrim Gozuacik Yacine Graba Martin Graef Giovanna E Granato Gary Dean Grant Steven Grant Giovanni Luca Gravina Douglas R Green Alexander Greenhough Michael T Greenwood Benedetto Grimaldi Frédéric Gros Charles Grose Jean-Francois Groulx Florian Gruber Paolo Grumati Tilman Grune Jun-Lin Guan Kun-Liang Guan Barbara Guerra Carlos Guillen Kailash Gulshan Jan Gunst Chuanyong Guo Lei Guo Ming Guo Wenjie Guo Xu-Guang Guo Andrea A Gust Åsa B Gustafsson Elaine Gutierrez Maximiliano G Gutierrez Ho-Shin Gwak Albert Haas James E Haber Shinji Hadano Monica Hagedorn David R Hahn Andrew J Halayko Anne Hamacher-Brady Kozo Hamada Ahmed Hamai Andrea Hamann Maho Hamasaki Isabelle Hamer Qutayba Hamid Ester M Hammond Feng Han Weidong Han James T Handa John A Hanover Malene Hansen Masaru Harada Ljubica Harhaji-Trajkovic J Wade Harper Abdel Halim Harrath Adrian L Harris James Harris Udo Hasler Peter Hasselblatt Kazuhisa Hasui Robert G Hawley Teresa S Hawley Congcong He Cynthia Y He Fengtian He Gu He Rong-Rong He Xian-Hui He You-Wen He Yu-Ying He Joan K Heath Marie-Josée Hébert Robert A Heinzen Gudmundur Vignir Helgason Michael Hensel Elizabeth P Henske Chengtao Her Paul K Herman Agustín Hernández Carlos Hernandez Sonia Hernández-Tiedra Claudio Hetz P Robin Hiesinger Katsumi Higaki Sabine Hilfiker Bradford G Hill Joseph A Hill William D Hill Keisuke Hino Daniel Hofius Paul Hofman Günter U Höglinger Jörg Höhfeld Marina K Holz Yonggeun Hong David A Hood Jeroen Jm Hoozemans Thorsten Hoppe Chin Hsu Chin-Yuan Hsu Li-Chung Hsu Dong Hu Guochang Hu Hong-Ming Hu Hongbo Hu Ming Chang Hu Yu-Chen Hu Zhuo-Wei Hu Fang Hua Ya Hua Canhua Huang Huey-Lan Huang Kuo-How Huang Kuo-Yang Huang Shile Huang Shiqian Huang Wei-Pang Huang Yi-Ran Huang Yong Huang Yunfei Huang Tobias B Huber Patricia Huebbe Won-Ki Huh Juha J Hulmi Gang Min Hur James H Hurley Zvenyslava Husak Sabah Na Hussain Salik Hussain Jung Jin Hwang Seungmin Hwang Thomas Is Hwang Atsuhiro Ichihara Yuzuru Imai Carol Imbriano Megumi Inomata Takeshi Into Valentina Iovane Juan L Iovanna Renato V Iozzo Nancy Y Ip Javier E Irazoqui Pablo Iribarren Yoshitaka Isaka Aleksandra J Isakovic Harry Ischiropoulos Jeffrey S Isenberg Mohammad Ishaq Hiroyuki Ishida Isao Ishii Jane E Ishmael Ciro Isidoro Ken-Ichi Isobe Erika Isono Shohreh Issazadeh-Navikas Koji Itahana Eisuke Itakura Andrei I Ivanov Anand Krishnan V Iyer José M Izquierdo Yotaro Izumi Valentina Izzo Marja Jäättelä Nadia Jaber Daniel John Jackson William T Jackson Tony George Jacob Thomas S Jacques Chinnaswamy Jagannath Ashish Jain Nihar Ranjan Jana Byoung Kuk Jang Alkesh Jani Bassam Janji Paulo Roberto Jannig Patric J Jansson Steve Jean Marina Jendrach Ju-Hong Jeon Niels Jessen Eui-Bae Jeung Kailiang Jia Lijun Jia Hong Jiang Hongchi Jiang Liwen Jiang Teng Jiang Xiaoyan Jiang Xuejun Jiang Xuejun Jiang Ying Jiang Yongjun Jiang Alberto Jiménez Cheng Jin Hongchuan Jin Lei Jin Meiyan Jin Shengkan Jin Umesh Kumar Jinwal Eun-Kyeong Jo Terje Johansen Daniel E Johnson Gail Vw Johnson James D Johnson Eric Jonasch Chris Jones Leo Ab Joosten Joaquin Jordan Anna-Maria Joseph Bertrand Joseph Annie M Joubert Dianwen Ju Jingfang Ju Hsueh-Fen Juan Katrin Juenemann Gábor Juhász Hye Seung Jung Jae U Jung Yong-Keun Jung Heinz Jungbluth Matthew J Justice Barry Jutten Nadeem O Kaakoush Kai Kaarniranta Allen Kaasik Tomohiro Kabuta Bertrand Kaeffer Katarina Kågedal Alon Kahana Shingo Kajimura Or Kakhlon Manjula Kalia Dhan V Kalvakolanu Yoshiaki Kamada Konstantinos Kambas Vitaliy O Kaminskyy Harm H Kampinga Mustapha Kandouz Chanhee Kang Rui Kang Tae-Cheon Kang Tomotake Kanki Thirumala-Devi Kanneganti Haruo Kanno Anumantha G Kanthasamy Marc Kantorow Maria Kaparakis-Liaskos Orsolya Kapuy Vassiliki Karantza Md Razaul Karim Parimal Karmakar Arthur Kaser Susmita Kaushik Thomas Kawula A Murat Kaynar Po-Yuan Ke Zun-Ji Ke John H Kehrl Kate E Keller Jongsook Kim Kemper Anne K Kenworthy Oliver Kepp Andreas Kern Santosh Kesari David Kessel Robin Ketteler Isis do Carmo Kettelhut Bilon Khambu Muzamil Majid Khan Vinoth Km Khandelwal Sangeeta Khare Juliann G Kiang Amy A Kiger Akio Kihara Arianna L Kim Cheol Hyeon Kim Deok Ryong Kim Do-Hyung Kim Eung Kweon Kim Hye Young Kim Hyung-Ryong Kim Jae-Sung Kim Jeong Hun Kim Jin Cheon Kim Jin Hyoung Kim Kwang Woon Kim Michael D Kim Moon-Moo Kim Peter K Kim Seong Who Kim Soo-Youl Kim Yong-Sun Kim Yonghyun Kim Adi Kimchi Alec C Kimmelman Tomonori Kimura Jason S King Karla Kirkegaard Vladimir Kirkin Lorrie A Kirshenbaum Shuji Kishi Yasuo Kitajima Katsuhiko Kitamoto Yasushi Kitaoka Kaio Kitazato Rudolf A Kley Walter T Klimecki Michael Klinkenberg Jochen Klucken Helene Knævelsrud Erwin Knecht Laura Knuppertz Jiunn-Liang Ko Satoru Kobayashi Jan C Koch Christelle Koechlin-Ramonatxo Ulrich Koenig Young Ho Koh Katja Köhler Sepp D Kohlwein Masato Koike Masaaki Komatsu Eiki Kominami Dexin Kong Hee Jeong Kong Eumorphia G Konstantakou Benjamin T Kopp Tamas Korcsmaros Laura Korhonen Viktor I Korolchuk Nadya V Koshkina Yanjun Kou Michael I Koukourakis Constantinos Koumenis Attila L Kovács Tibor Kovács Werner J Kovacs Daisuke Koya Claudine Kraft Dimitri Krainc Helmut Kramer Tamara Kravic-Stevovic Wilhelm Krek Carole Kretz-Remy Roswitha Krick Malathi Krishnamurthy Janos Kriston-Vizi Guido Kroemer Michael C Kruer Rejko Kruger Nicholas T Ktistakis Kazuyuki Kuchitsu Christian Kuhn Addanki Pratap Kumar Anuj Kumar Ashok Kumar Deepak Kumar Dhiraj Kumar Rakesh Kumar Sharad Kumar Mondira Kundu Hsing-Jien Kung Atsushi Kuno Sheng-Han Kuo Jeff Kuret Tino Kurz Terry Kwok Taeg Kyu Kwon Yong Tae Kwon Irene Kyrmizi Albert R La Spada Frank Lafont Tim Lahm Aparna Lakkaraju Truong Lam Trond Lamark Steve Lancel Terry H Landowski Darius J R Lane Jon D Lane Cinzia Lanzi Pierre Lapaquette Louis R Lapierre Jocelyn Laporte Johanna Laukkarinen Gordon W Laurie Sergio Lavandero Lena Lavie Matthew J LaVoie Betty Yuen Kwan Law Helen Ka-Wai Law Kelsey B Law Robert Layfield Pedro A Lazo Laurent Le Cam Karine G Le Roch Hervé Le Stunff Vijittra Leardkamolkarn Marc Lecuit Byung-Hoon Lee Che-Hsin Lee Erinna F Lee Gyun Min Lee He-Jin Lee Hsinyu Lee Jae Keun Lee Jongdae Lee Ju-Hyun Lee Jun Hee Lee Michael Lee Myung-Shik Lee Patty J Lee Sam W Lee Seung-Jae Lee Shiow-Ju Lee Stella Y Lee Sug Hyung Lee Sung Sik Lee Sung-Joon Lee Sunhee Lee Ying-Ray Lee Yong J Lee Young H Lee Christiaan Leeuwenburgh Sylvain Lefort Renaud Legouis Jinzhi Lei Qun-Ying Lei David A Leib Gil Leibowitz Istvan Lekli Stéphane D Lemaire John J Lemasters Marius K Lemberg Antoinette Lemoine Shuilong Leng Guido Lenz Paola Lenzi Lilach O Lerman Daniele Lettieri Barbato Julia I-Ju Leu Hing Y Leung Beth Levine Patrick A Lewis Frank Lezoualc'h Chi Li Faqiang Li Feng-Jun Li Jun Li Ke Li Lian Li Min Li Min Li Qiang Li Rui Li Sheng Li Wei Li Wei Li Xiaotao Li Yumin Li Jiqin Lian Chengyu Liang Qiangrong Liang Yulin Liao Joana Liberal Pawel P Liberski Pearl Lie Andrew P Lieberman Hyunjung Jade Lim Kah-Leong Lim Kyu Lim Raquel T Lima Chang-Shen Lin Chiou-Feng Lin Fang Lin Fangming Lin Fu-Cheng Lin Kui Lin Kwang-Huei Lin Pei-Hui Lin Tianwei Lin Wan-Wan Lin Yee-Shin Lin Yong Lin Rafael Linden Dan Lindholm Lisa M Lindqvist Paul Lingor Andreas Linkermann Lance A Liotta Marta M Lipinski Vitor A Lira Michael P Lisanti Paloma B Liton Bo Liu Chong Liu Chun-Feng Liu Fei Liu Hung-Jen Liu Jianxun Liu Jing-Jing Liu Jing-Lan Liu Ke Liu Leyuan Liu Liang Liu Quentin Liu Rong-Yu Liu Shiming Liu Shuwen Liu Wei Liu Xian-De Liu Xiangguo Liu Xiao-Hong Liu Xinfeng Liu Xu Liu Xueqin Liu Yang Liu Yule Liu Zexian Liu Zhe Liu Juan P Liuzzi Gérard Lizard Mila Ljujic Irfan J Lodhi Susan E Logue Bal L Lokeshwar Yun Chau Long Sagar Lonial Benjamin Loos Carlos López-Otín Cristina López-Vicario Mar Lorente Philip L Lorenzi Péter Lõrincz Marek Los Michael T Lotze Penny E Lovat Binfeng Lu Bo Lu Jiahong Lu Qing Lu She-Min Lu Shuyan Lu Yingying Lu Frédéric Luciano Shirley Luckhart John Milton Lucocq Paula Ludovico Aurelia Lugea Nicholas W Lukacs Julian J Lum Anders H Lund Honglin Luo Jia Luo Shouqing Luo Claudio Luparello Timothy Lyons Jianjie Ma Yi Ma Yong Ma Zhenyi Ma Juliano Machado Glaucia M Machado-Santelli Fernando Macian Gustavo C MacIntosh Jeffrey P MacKeigan Kay F Macleod John D MacMicking Lee Ann MacMillan-Crow Frank Madeo Muniswamy Madesh Julio Madrigal-Matute Akiko Maeda Tatsuya Maeda Gustavo Maegawa Emilia Maellaro Hannelore Maes Marta Magariños Kenneth Maiese Tapas K Maiti Luigi Maiuri Maria Chiara Maiuri Carl G Maki Roland Malli Walter Malorni Alina Maloyan Fathia Mami-Chouaib Na Man Joseph D Mancias Eva-Maria Mandelkow Michael A Mandell Angelo A Manfredi Serge N Manié Claudia Manzoni Kai Mao Zixu Mao Zong-Wan Mao Philippe Marambaud Anna Maria Marconi Zvonimir Marelja Gabriella Marfe Marta Margeta Eva Margittai Muriel Mari Francesca V Mariani Concepcio Marin Sara Marinelli Guillermo Mariño Ivanka Markovic Rebecca Marquez Alberto M Martelli Sascha Martens Katie R Martin Seamus J Martin Shaun Martin Miguel A Martin-Acebes Paloma Martín-Sanz Camille Martinand-Mari Wim Martinet Jennifer Martinez Nuria Martinez-Lopez Ubaldo Martinez-Outschoorn Moisés Martínez-Velázquez Marta Martinez-Vicente Waleska Kerllen Martins Hirosato Mashima James A Mastrianni Giuseppe Matarese Paola Matarrese Roberto Mateo Satoaki Matoba Naomichi Matsumoto Takehiko Matsushita Akira Matsuura Takeshi Matsuzawa Mark P Mattson Soledad Matus Norma Maugeri Caroline Mauvezin Andreas Mayer Dusica Maysinger Guillermo D Mazzolini Mary Kate McBrayer Kimberly McCall Craig McCormick Gerald M McInerney Skye C McIver Sharon McKenna John J McMahon Iain A McNeish Fatima Mechta-Grigoriou Jan Paul Medema Diego L Medina Klara Megyeri Maryam Mehrpour Jawahar L Mehta Yide Mei Ute-Christiane Meier Alfred J Meijer Alicia Meléndez Gerry Melino Sonia Melino Edesio Jose Tenorio de Melo Maria A Mena Marc D Meneghini Javier A Menendez Regina Menezes Liesu Meng Ling-Hua Meng Songshu Meng Rossella Menghini A Sue Menko Rubem Fs Menna-Barreto Manoj B Menon Marco A Meraz-Ríos Giuseppe Merla Luciano Merlini Angelica M Merlot Andreas Meryk Stefania Meschini Joel N Meyer Man-Tian Mi Chao-Yu Miao Lucia Micale Simon Michaeli Carine Michiels Anna Rita Migliaccio Anastasia Susie Mihailidou Dalibor Mijaljica Katsuhiko Mikoshiba Enrico Milan Leonor Miller-Fleming Gordon B Mills Ian G Mills Georgia Minakaki Berge A Minassian Xiu-Fen Ming Farida Minibayeva Elena A Minina Justine D Mintern Saverio Minucci Antonio Miranda-Vizuete Claire H Mitchell Shigeki Miyamoto Keisuke Miyazawa Noboru Mizushima Katarzyna Mnich Baharia Mograbi Simin Mohseni Luis Ferreira Moita Marco Molinari Maurizio Molinari Andreas Buch Møller Bertrand Mollereau Faustino Mollinedo Marco Mongillo Martha M Monick Serena Montagnaro Craig Montell Darren J Moore Michael N Moore Rodrigo Mora-Rodriguez Paula I Moreira Etienne Morel Maria Beatrice Morelli Sandra Moreno Michael J Morgan Arnaud Moris Yuji Moriyasu Janna L Morrison Lynda A Morrison Eugenia Morselli Jorge Moscat Pope L Moseley Serge Mostowy Elisa Motori Denis Mottet Jeremy C Mottram Charbel E-H Moussa Vassiliki E Mpakou Hasan Mukhtar Jean M Mulcahy Levy Sylviane Muller Raquel Muñoz-Moreno Cristina Muñoz-Pinedo Christian Münz Maureen E Murphy James T Murray Aditya Murthy Indira U Mysorekar Ivan R Nabi Massimo Nabissi Gustavo A Nader Yukitoshi Nagahara Yoshitaka Nagai Kazuhiro Nagata Anika Nagelkerke Péter Nagy Samisubbu R Naidu Sreejayan Nair Hiroyasu Nakano Hitoshi Nakatogawa Meera Nanjundan Gennaro Napolitano Naweed I Naqvi Roberta Nardacci Derek P Narendra Masashi Narita Anna Chiara Nascimbeni Ramesh Natarajan Luiz C Navegantes Steffan T Nawrocki Taras Y Nazarko Volodymyr Y Nazarko Thomas Neill Luca M Neri Mihai G Netea Romana T Netea-Maier Bruno M Neves Paul A Ney Ioannis P Nezis Hang Tt Nguyen Huu Phuc Nguyen Anne-Sophie Nicot Hilde Nilsen Per Nilsson Mikio Nishimura Ichizo Nishino Mireia Niso-Santano Hua Niu Ralph A Nixon Vincent Co Njar Takeshi Noda Angelika A Noegel Elsie Magdalena Nolte Erik Norberg Koenraad K Norga Sakineh Kazemi Noureini Shoji Notomi Lucia Notterpek Karin Nowikovsky Nobuyuki Nukina Thorsten Nürnberger Valerie B O'Donnell Tracey O'Donovan Peter J O'Dwyer Ina Oehme Clara L Oeste Michinaga Ogawa Besim Ogretmen Yuji Ogura Young J Oh Masaki Ohmuraya Takayuki Ohshima Rani Ojha Koji Okamoto Toshiro Okazaki F Javier Oliver Karin Ollinger Stefan Olsson Daniel P Orban Paulina Ordonez Idil Orhon Laszlo Orosz Eyleen J O'Rourke Helena Orozco Angel L Ortega Elena Ortona Laura D Osellame Junko Oshima Shigeru Oshima Heinz D Osiewacz Takanobu Otomo Kinya Otsu Jing-Hsiung James Ou Tiago F Outeiro Dong-Yun Ouyang Hongjiao Ouyang Michael Overholtzer Michelle A Ozbun P Hande Ozdinler Bulent Ozpolat Consiglia Pacelli Paolo Paganetti Guylène Page Gilles Pages Ugo Pagnini Beata Pajak Stephen C Pak Karolina Pakos-Zebrucka Nazzy Pakpour Zdena Palková Francesca Palladino Kathrin Pallauf Nicolas Pallet Marta Palmieri Søren R Paludan Camilla Palumbo Silvia Palumbo Olatz Pampliega Hongming Pan Wei Pan Theocharis Panaretakis Aseem Pandey Areti Pantazopoulou Zuzana Papackova Daniela L Papademetrio Issidora Papassideri Alessio Papini Nirmala Parajuli Julian Pardo Vrajesh V Parekh Giancarlo Parenti Jong-In Park Junsoo Park Ohkmae K Park Roy Parker Rosanna Parlato Jan B Parys Katherine R Parzych Jean-Max Pasquet Benoit Pasquier Kishore Bs Pasumarthi Daniel Patschan Cam Patterson Sophie Pattingre Scott Pattison Arnim Pause Hermann Pavenstädt Flaminia Pavone Zully Pedrozo Fernando J Peña Miguel A Peñalva Mario Pende Jianxin Peng Fabio Penna Josef M Penninger Anna Pensalfini Salvatore Pepe Gustavo Js Pereira Paulo C Pereira Verónica Pérez-de la Cruz María Esther Pérez-Pérez Diego Pérez-Rodríguez Dolores Pérez-Sala Celine Perier Andras Perl David H Perlmutter Ida Perrotta Shazib Pervaiz Maija Pesonen Jeffrey E Pessin Godefridus J Peters Morten Petersen Irina Petrache Basil J Petrof Goran Petrovski James M Phang Mauro Piacentini Marina Pierdominici Philippe Pierre Valérie Pierrefite-Carle Federico Pietrocola Felipe X Pimentel-Muiños Mario Pinar Benjamin Pineda Ronit Pinkas-Kramarski Marcello Pinti Paolo Pinton Bilal Piperdi James M Piret Leonidas C Platanias Harald W Platta Edward D Plowey Stefanie Pöggeler Marc Poirot Peter Polčic Angelo Poletti Audrey H Poon Hana Popelka Blagovesta Popova Izabela Poprawa Shibu M Poulose Joanna Poulton Scott K Powers Ted Powers Mercedes Pozuelo-Rubio Krisna Prak Reinhild Prange Mark Prescott Muriel Priault Sharon Prince Richard L Proia Tassula Proikas-Cezanne Holger Prokisch Vasilis J Promponas Karin Przyklenk Rosa Puertollano Subbiah Pugazhenthi Luigi Puglielli Aurora Pujol Julien Puyal Dohun Pyeon Xin Qi Wen-Bin Qian Zheng-Hong Qin Yu Qiu Ziwei Qu Joe Quadrilatero Frederick Quinn Nina Raben Hannah Rabinowich Flavia Radogna Michael J Ragusa Mohamed Rahmani Komal Raina Sasanka Ramanadham Rajagopal Ramesh Abdelhaq Rami Sarron Randall-Demllo Felix Randow Hai Rao V Ashutosh Rao Blake B Rasmussen Tobias M Rasse Edward A Ratovitski Pierre-Emmanuel Rautou Swapan K Ray Babak Razani Bruce H Reed Fulvio Reggiori Markus Rehm Andreas S Reichert Theo Rein David J Reiner Eric Reits Jun Ren Xingcong Ren Maurizio Renna Jane Eb Reusch Jose L Revuelta Leticia Reyes Alireza R Rezaie Robert I Richards Des R Richardson Clémence Richetta Michael A Riehle Bertrand H Rihn Yasuko Rikihisa Brigit E Riley Gerald Rimbach Maria Rita Rippo Konstantinos Ritis Federica Rizzi Elizete Rizzo Peter J Roach Jeffrey Robbins Michel Roberge Gabriela Roca Maria Carmela Roccheri Sonia Rocha Cecilia Mp Rodrigues Clara I Rodríguez Santiago Rodriguez de Cordoba Natalia Rodriguez-Muela Jeroen Roelofs Vladimir V Rogov Troy T Rohn Bärbel Rohrer Davide Romanelli Luigina Romani Patricia Silvia Romano M Isabel G Roncero Jose Luis Rosa Alicia Rosello Kirill V Rosen Philip Rosenstiel Magdalena Rost-Roszkowska Kevin A Roth Gael Roué Mustapha Rouis Kasper M Rouschop Daniel T Ruan Diego Ruano David C Rubinsztein Edmund B Rucker Assaf Rudich Emil Rudolf Ruediger Rudolf Markus A Ruegg Carmen Ruiz-Roldan Avnika Ashok Ruparelia Paola Rusmini David W Russ Gian Luigi Russo Giuseppe Russo Rossella Russo Tor Erik Rusten Victoria Ryabovol Kevin M Ryan Stefan W Ryter David M Sabatini Michael Sacher Carsten Sachse Michael N Sack Junichi Sadoshima Paul Saftig Ronit Sagi-Eisenberg Sumit Sahni Pothana Saikumar Tsunenori Saito Tatsuya Saitoh Koichi Sakakura Machiko Sakoh-Nakatogawa Yasuhito Sakuraba María Salazar-Roa Paolo Salomoni Ashok K Saluja Paul M Salvaterra Rosa Salvioli Afshin Samali Anthony Mj Sanchez José A Sánchez-Alcázar Ricardo Sanchez-Prieto Marco Sandri Miguel A Sanjuan Stefano Santaguida Laura Santambrogio Giorgio Santoni Claudia Nunes Dos Santos Shweta Saran Marco Sardiello Graeme Sargent Pallabi Sarkar Sovan Sarkar Maria Rosa Sarrias Minnie M Sarwal Chihiro Sasakawa Motoko Sasaki Miklos Sass Ken Sato Miyuki Sato Joseph Satriano Niramol Savaraj Svetlana Saveljeva Liliana Schaefer Ulrich E Schaible Michael Scharl Hermann M Schatzl Randy Schekman Wiep Scheper Alfonso Schiavi Hyman M Schipper Hana Schmeisser Jens Schmidt Ingo Schmitz Bianca E Schneider E Marion Schneider Jaime L Schneider Eric A Schon Miriam J Schönenberger Axel H Schönthal Daniel F Schorderet Bernd Schröder Sebastian Schuck Ryan J Schulze Melanie Schwarten Thomas L Schwarz Sebastiano Sciarretta Kathleen Scotto A Ivana Scovassi Robert A Screaton Mark Screen Hugo Seca Simon Sedej Laura Segatori Nava Segev Per O Seglen Jose M Seguí-Simarro Juan Segura-Aguilar Ekihiro Seki Christian Sell Iban Seiliez Clay F Semenkovich Gregg L Semenza Utpal Sen Andreas L Serra Ana Serrano-Puebla Hiromi Sesaki Takao Setoguchi Carmine Settembre John J Shacka Ayesha N Shajahan-Haq Irving M Shapiro Shweta Sharma Hua She C-K James Shen Chiung-Chyi Shen Han-Ming Shen Sanbing Shen Weili Shen Rui Sheng Xianyong Sheng Zu-Hang Sheng Trevor G Shepherd Junyan Shi Qiang Shi Qinghua Shi Yuguang Shi Shusaku Shibutani Kenichi Shibuya Yoshihiro Shidoji Jeng-Jer Shieh Chwen-Ming Shih Yohta Shimada Shigeomi Shimizu Dong Wook Shin Mari L Shinohara Michiko Shintani Takahiro Shintani Tetsuo Shioi Ken Shirabe Ronit Shiri-Sverdlov Orian Shirihai Gordon C Shore Chih-Wen Shu Deepak Shukla Andriy A Sibirny Valentina Sica Christina J Sigurdson Einar M Sigurdsson Puran Singh Sijwali Beata Sikorska Wilian A Silveira Sandrine Silvente-Poirot Gary A Silverman Jan Simak Thomas Simmet Anna Katharina Simon Hans-Uwe Simon Cristiano Simone Matias Simons Anne Simonsen Rajat Singh Shivendra V Singh Shrawan K Singh Debasish Sinha Sangita Sinha Frank A Sinicrope Agnieszka Sirko Kapil Sirohi Balindiwe Jn Sishi Annie Sittler Parco M Siu Efthimios Sivridis Anna Skwarska Ruth Slack Iva Slaninová Nikolai Slavov Soraya S Smaili Keiran Sm Smalley Duncan R Smith Stefaan J Soenen Scott A Soleimanpour Anita Solhaug Kumaravel Somasundaram Jin H Son Avinash Sonawane Chunjuan Song Fuyong Song Hyun Kyu Song Ju-Xian Song Wei Song Kai Y Soo Anil K Sood Tuck Wah Soong Virawudh Soontornniyomkij Maurizio Sorice Federica Sotgia David R Soto-Pantoja Areechun Sotthibundhu Maria João Sousa Herman P Spaink Paul N Span Anne Spang Janet D Sparks Peter G Speck Stephen A Spector Claudia D Spies Wolfdieter Springer Daret St Clair Alessandra Stacchiotti Bart Staels Michael T Stang Daniel T Starczynowski Petro Starokadomskyy Clemens Steegborn John W Steele Leonidas Stefanis Joan Steffan Christine M Stellrecht Harald Stenmark Tomasz M Stepkowski Stęphan T Stern Craig Stevens Brent R Stockwell Veronika Stoka Zuzana Storchova Björn Stork Vassilis Stratoulias Dimitrios J Stravopodis Pavel Strnad Anne Marie Strohecker Anna-Lena Ström Per Stromhaug Jiri Stulik Yu-Xiong Su Zhaoliang Su Carlos S Subauste Srinivasa Subramaniam Carolyn M Sue Sang Won Suh Xinbing Sui Supawadee Sukseree David Sulzer Fang-Lin Sun Jiaren Sun Jun Sun Shi-Yong Sun Yang Sun Yi Sun Yingjie Sun Vinod Sundaramoorthy Joseph Sung Hidekazu Suzuki Kuninori Suzuki Naoki Suzuki Tadashi Suzuki Yuichiro J Suzuki Michele S Swanson Charles Swanton Karl Swärd Ghanshyam Swarup Sean T Sweeney Paul W Sylvester Zsuzsanna Szatmari Eva Szegezdi Peter W Szlosarek Heinrich Taegtmeyer Marco Tafani Emmanuel Taillebourg Stephen Wg Tait Krisztina Takacs-Vellai Yoshinori Takahashi Szabolcs Takáts Genzou Takemura Nagio Takigawa Nicholas J Talbot Elena Tamagno Jerome Tamburini Cai-Ping Tan Lan Tan Mei Lan Tan Ming Tan Yee-Joo Tan Keiji Tanaka Masaki Tanaka Daolin Tang Dingzhong Tang Guomei Tang Isei Tanida Kunikazu Tanji Bakhos A Tannous Jose A Tapia Inmaculada Tasset-Cuevas Marc Tatar Iman Tavassoly Nektarios Tavernarakis Allen Taylor Graham S Taylor Gregory A Taylor J Paul Taylor Mark J Taylor Elena V Tchetina Andrew R Tee Fatima Teixeira-Clerc Sucheta Telang Tewin Tencomnao Ba-Bie Teng Ru-Jeng Teng Faraj Terro Gianluca Tettamanti Arianne L Theiss Anne E Theron Kelly Jean Thomas Marcos P Thomé Paul G Thomes Andrew Thorburn Jeremy Thorner Thomas Thum Michael Thumm Teresa Lm Thurston Ling Tian Andreas Till Jenny Pan-Yun Ting Vladimir I Titorenko Lilach Toker Stefano Toldo Sharon A Tooze Ivan Topisirovic Maria Lyngaas Torgersen Liliana Torosantucci Alicia Torriglia Maria Rosaria Torrisi Cathy Tournier Roberto Towns Vladimir Trajkovic Leonardo H Travassos Gemma Triola Durga Nand Tripathi Daniela Trisciuoglio Rodrigo Troncoso Ioannis P Trougakos Anita C Truttmann Kuen-Jer Tsai Mario P Tschan Yi-Hsin Tseng Takayuki Tsukuba Allan Tsung Andrey S Tsvetkov Shuiping Tu Hsing-Yu Tuan Marco Tucci David A Tumbarello Boris Turk Vito Turk Robin Fb Turner Anders A Tveita Suresh C Tyagi Makoto Ubukata Yasuo Uchiyama Andrej Udelnow Takashi Ueno Midori Umekawa Rika Umemiya-Shirafuji Benjamin R Underwood Christian Ungermann Rodrigo P Ureshino Ryo Ushioda Vladimir N Uversky Néstor L Uzcátegui Thomas Vaccari Maria I Vaccaro Libuše Váchová Helin Vakifahmetoglu-Norberg Rut Valdor Enza Maria Valente Francois Vallette Angela M Valverde Greet Van den Berghe Ludo Van Den Bosch Gijs R van den Brink F Gisou van der Goot Ida J van der Klei Luc Jw van der Laan Wouter G van Doorn Marjolein van Egmond Kenneth L van Golen Luc Van Kaer Menno van Lookeren Campagne Peter Vandenabeele Wim Vandenberghe Ilse Vanhorebeek Isabel Varela-Nieto M Helena Vasconcelos Radovan Vasko Demetrios G Vavvas Ignacio Vega-Naredo Guillermo Velasco Athanassios D Velentzas Panagiotis D Velentzas Tibor Vellai Edo Vellenga Mikkel Holm Vendelbo Kartik Venkatachalam Natascia Ventura Salvador Ventura Patrícia St Veras Mireille Verdier Beata G Vertessy Andrea Viale Michel Vidal Helena L A Vieira Richard D Vierstra Nadarajah Vigneswaran Neeraj Vij Miquel Vila Margarita Villar Victor H Villar Joan Villarroya Cécile Vindis Giampietro Viola Maria Teresa Viscomi Giovanni Vitale Dan T Vogl Olga V Voitsekhovskaja Clarissa von Haefen Karin von Schwarzenberg Daniel E Voth Valérie Vouret-Craviari Kristina Vuori Jatin M Vyas Christian Waeber Cheryl Lyn Walker Mark J Walker Jochen Walter Lei Wan Xiangbo Wan Bo Wang Caihong Wang Chao-Yung Wang Chengshu Wang Chenran Wang Chuangui Wang Dong Wang Fen Wang Fuxin Wang Guanghui Wang Hai-Jie Wang Haichao Wang Hong-Gang Wang Hongmin Wang Horng-Dar Wang Jing Wang Junjun Wang Mei Wang Mei-Qing Wang Pei-Yu Wang Peng Wang Richard C Wang Shuo Wang Ting-Fang Wang Xian Wang Xiao-Jia Wang Xiao-Wei Wang Xin Wang Xuejun Wang Yan Wang Yanming Wang Ying Wang Ying-Jan Wang Yipeng Wang Yu Wang Yu Tian Wang Yuqing Wang Zhi-Nong Wang Pablo Wappner Carl Ward Diane McVey Ward Gary Warnes Hirotaka Watada Yoshihisa Watanabe Kei Watase Timothy E Weaver Colin D Weekes Jiwu Wei Thomas Weide Conrad C Weihl Günther Weindl Simone Nardin Weis Longping Wen Xin Wen Yunfei Wen Benedikt Westermann Cornelia M Weyand Anthony R White Eileen White J Lindsay Whitton Alexander J Whitworth Joëlle Wiels Franziska Wild Manon E Wildenberg Tom Wileman Deepti Srinivas Wilkinson Simon Wilkinson Dieter Willbold Chris Williams Katherine Williams Peter R Williamson Konstanze F Winklhofer Steven S Witkin Stephanie E Wohlgemuth Thomas Wollert Ernst J Wolvetang Esther Wong G William Wong Richard W Wong Vincent Kam Wai Wong Elizabeth A Woodcock Karen L Wright Chunlai Wu Defeng Wu Gen Sheng Wu Jian Wu Junfang Wu Mian Wu Min Wu Shengzhou Wu William Kk Wu Yaohua Wu Zhenlong Wu Cristina Pr Xavier Ramnik J Xavier Gui-Xian Xia Tian Xia Weiliang Xia Yong Xia Hengyi Xiao Jian Xiao Shi Xiao Wuhan Xiao Chuan-Ming Xie Zhiping Xie Zhonglin Xie Maria Xilouri Yuyan Xiong Chuanshan Xu Congfeng Xu Feng Xu Haoxing Xu Hongwei Xu Jian Xu Jianzhen Xu Jinxian Xu Liang Xu Xiaolei Xu Yangqing Xu Ye Xu Zhi-Xiang Xu Ziheng Xu Yu Xue Takahiro Yamada Ai Yamamoto Koji Yamanaka Shunhei Yamashina Shigeko Yamashiro Bing Yan Bo Yan Xianghua Yan Zhen Yan Yasuo Yanagi Dun-Sheng Yang Jin-Ming Yang Liu Yang Minghua Yang Pei-Ming Yang Peixin Yang Qian Yang Wannian Yang Wei Yuan Yang Xuesong Yang Yi Yang Ying Yang Zhifen Yang Zhihong Yang Meng-Chao Yao Pamela J Yao Xiaofeng Yao Zhenyu Yao Zhiyuan Yao Linda S Yasui Mingxiang Ye Barry Yedvobnick Behzad Yeganeh Elizabeth S Yeh Patricia L Yeyati Fan Yi Long Yi Xiao-Ming Yin Calvin K Yip Yeong-Min Yoo Young Hyun Yoo Seung-Yong Yoon Ken-Ichi Yoshida Tamotsu Yoshimori Ken H Young Huixin Yu Jane J Yu Jin-Tai Yu Jun Yu Li Yu W Haung Yu Xiao-Fang Yu Zhengping Yu Junying Yuan Zhi-Min Yuan Beatrice Yjt Yue Jianbo Yue Zhenyu Yue David N Zacks Eldad Zacksenhaus Nadia Zaffaroni Tania Zaglia Zahra Zakeri Vincent Zecchini Jinsheng Zeng Min Zeng Qi Zeng Antonis S Zervos Donna D Zhang Fan Zhang Guo Zhang Guo-Chang Zhang Hao Zhang Hong Zhang Hong Zhang Hongbing Zhang Jian Zhang Jian Zhang Jiangwei Zhang Jianhua Zhang Jing-Pu Zhang Li Zhang Lin Zhang Lin Zhang Long Zhang Ming-Yong Zhang Xiangnan Zhang Xu Dong Zhang Yan Zhang Yang Zhang Yanjin Zhang Yingmei Zhang Yunjiao Zhang Mei Zhao Wei-Li Zhao Xiaonan Zhao Yan G Zhao Ying Zhao Yongchao Zhao Yu-Xia Zhao Zhendong Zhao Zhizhuang J Zhao Dexian Zheng Xi-Long Zheng Xiaoxiang Zheng Boris Zhivotovsky Qing Zhong Guang-Zhou Zhou Guofei Zhou Huiping Zhou Shu-Feng Zhou Xu-Jie Zhou Hongxin Zhu Hua Zhu Wei-Guo Zhu Wenhua Zhu Xiao-Feng Zhu Yuhua Zhu Shi-Mei Zhuang Xiaohong Zhuang Elio Ziparo Christos E Zois Teresa Zoladek Wei-Xing Zong Antonio Zorzano Susu M Zughaier

Autophagy 2016 ;12(1):1-222

kb Emory University, School of Medicine , Department of Microbiology and Immunology , Atlanta , GA , USA.

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October 2016

Introduction to the Robert Bittman Memorial Issue.

Authors:
Gemma Fabrias Alexander Greer Ravi S Lankalapalli Robert Engel

Chem Phys Lipids 2016 Jan;194

Department of Chemistry and Biochemistry, and Graduate Center, Queens College of the City University of New York, Flushing, NY 11367, USA.

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January 2016

Effect of prenatal steroidal inhibition of sPLA2 in a rat model of preterm lung.

Authors:
Ana Remesal Daniele De Luca Laura San Feliciano Maria Isidoro-Garcia Angelo Minucci Krizia Pocino Josefina Casas Gemma Fabrias Ettore D Capoluongo Dolores Ludena de la Cruz

Pulm Pharmacol Ther 2016 Feb 17;36:31-6. Epub 2015 Dec 17.

NICU and Animal Lab, Dept of Paediatrics, University Hospital of Salamanca, Paseo de San Vicente182, 37007 Salamanca, Spain.

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February 2016

Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis.

Authors:
Laura Martínez Sandra Torres Anna Baulies Cristina Alarcón-Vila Montserrat Elena Gemma Fabriàs Josefina Casas Joan Caballeria Jose C Fernandez-Checa Carmen García-Ruiz

Oncotarget 2015 Dec;6(39):41479-96

Cell Death and Proliferation, Institute of Biomedical Research of Barcelona (IIBB), CSIC, Barcelona, Spain.

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December 2015

De novo ceramide synthesis is involved in acute inflammation during labor.

Authors:
Paola Signorelli Laura Avagliano Marta R Reforgiato Nadia Toppi Josefina Casas Gemma Fabriàs Anna Maria Marconi Riccardo Ghidoni Anna Caretti

Biol Chem 2016 Jan;397(2):147-55

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January 2016

Introduction to the special issue: Inhibitors of enzymes involved in lipid metabolism.

Authors:
Gemma Fabrias Richard M Epand

Chem Phys Lipids 2016 May 17;197:1-2. Epub 2015 Aug 17.

Department of Biochemistry and Biomedical Sciences, McMaster University, Ontario, Canada.

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May 2016

Activity of neutral and alkaline ceramidases on fluorogenic N-acylated coumarin-containing aminodiols.

Authors:
Mireia Casasampere Luz Camacho Francesca Cingolani Josefina Casas Meritxell Egido-Gabás José Luís Abad Carmen Bedia Ruijuan Xu Kai Wang Daniel Canals Yusuf A Hannun Cungui Mao Gemma Fabrias

J Lipid Res 2015 Oct 18;56(10):2019-28. Epub 2015 Aug 18.

Consejo Superior de Investigaciones Científicas (CSIC), Institut de Química Avançada de Catalunya (IQAC-CSIC), Research Unit on Bioactive Molecules (RUBAM), 08034 Barcelona, Spain.

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October 2015

Obesogens beyond Vertebrates: Lipid Perturbation by Tributyltin in the Crustacean Daphnia magna.

Authors:
Rita Jordão Josefina Casas Gemma Fabrias Bruno Campos Benjamín Piña Marco F L Lemos Amadeu M V M Soares Romà Tauler Carlos Barata

Environ Health Perspect 2015 Aug 24;123(8):813-9. Epub 2015 Mar 24.

Department of Environmental Chemistry, Institute of Environmental Assessment and Water Research (IDAEA), Spanish Research Council (IDAEA, CSIC), Barcelona, Spain.

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August 2015

Natural grape extracts regulate colon cancer cells malignancy.

Authors:
Paola Signorelli Carlotta Fabiani Andrea Brizzolari Rita Paroni Josefina Casas Gemma Fabriàs Dario Rossi Riccardo Ghidoni Anna Caretti

Nutr Cancer 2015 23;67(3):494-503. Epub 2015 Feb 23.

a Department of Health Sciences , University of Milan , Milan , Italy , and San Paolo Hospital , Milan , Italy.

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December 2015

Azide-tagged sphingolipids: new tools for metabolic flux analysis.

Authors:
María Garrido José Luis Abad Gemma Fabriàs Josefina Casas Antonio Delgado

Chembiochem 2015 Mar 11;16(4):641-50. Epub 2015 Feb 11.

Research Unit on BioActive Molecules, Department of Biomedicinal Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Jordi Girona 18-26; 08034 Barcelona (Spain).

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March 2015

Coordinated regulation of the orosomucoid-like gene family expression controls de novo ceramide synthesis in mammalian cells.

Authors:
Kerstin Kiefer Amado Carreras-Sureda Roberto García-López Fanny Rubio-Moscardó Josefina Casas Gemma Fabriàs Rubén Vicente

J Biol Chem 2015 Jan 17;290(5):2822-30. Epub 2014 Dec 17.

From the Laboratory of Molecular Physiology and Channelopathies, Department of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003 Barcelona, Spain and

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January 2015

On-tissue localization of ceramides and other sphingolipids by MALDI mass spectrometry imaging.

Authors:
E Ellen Jones Shaalee Dworski Daniel Canals Josefina Casas Gemma Fabrias Drew Schoenling Thierry Levade Chadrick Denlinger Yusuf A Hannun Jeffrey A Medin Richard R Drake

Anal Chem 2014 Aug 8;86(16):8303-11. Epub 2014 Aug 8.

Department of Cell and Molecular Pharmacology and MUSC Proteomics Center, Medical University of South Carolina , 173 Ashley Avenue, Charleston, South Carolina 29425, United States.

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August 2014

Inhibition of dihydroceramide desaturase activity by the sphingosine kinase inhibitor SKI II.

Authors:
Francesca Cingolani Mireia Casasampere Pol Sanllehí Josefina Casas Jordi Bujons Gemma Fabrias

J Lipid Res 2014 Aug 29;55(8):1711-20. Epub 2014 May 29.

Research Unit on BioActive Molecules (RUBAM), Departments of Biomedicinal Chemistry Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), 08034 Barcelona, Spain.

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August 2014

Long-term increased carnitine palmitoyltransferase 1A expression in ventromedial hypotalamus causes hyperphagia and alters the hypothalamic lipidomic profile.

Authors:
Paula Mera Joan Francesc Mir Gemma Fabriàs Josefina Casas Ana S H Costa Maria Ida Malandrino José-Antonio Fernández-López Xavier Remesar Su Gao Shigeru Chohnan Maria Sol Rodríguez-Peña Harald Petry Guillermina Asins Fausto G Hegardt Laura Herrero Dolors Serra

PLoS One 2014 12;9(5):e97195. Epub 2014 May 12.

Department of Biochemistry and Molecular Biology, Facultat de Farmàcia, Universitat de Barcelona and Institut de Biomedicina de la Universitat de Barcelona (IBUB) and CIBER Fisiopatología de la Obesidad y la Nutrición (CIBERobn), Instituto de Salud Carlos III, Barcelona, Spain.

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June 2015

Molecular cloning and knockdown of galactocerebrosidase in zebrafish: new insights into the pathogenesis of Krabbe's disease.

Authors:
Daniela Zizioli Michela Guarienti Chiara Tobia Giuseppina Gariano Giuseppe Borsani Roberto Bresciani Roberto Ronca Edoardo Giacopuzzi Augusto Preti Germano Gaudenzi Mirella Belleri Emanuela Di Salle Gemma Fabrias Josefina Casas Domenico Ribatti Eugenio Monti Marco Presta

Biochim Biophys Acta 2014 Apr 24;1842(4):665-75. Epub 2014 Jan 24.

Unit of Oncology and Experimental Immunology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy. Electronic address:

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April 2014

A lovastatin-elicited genetic program inhibits M2 macrophage polarization and enhances T cell infiltration into spontaneous mouse mammary tumors.

Authors:
Emilia Mira Lorena Carmona-Rodríguez Manuel Tardáguila Iñigo Azcoitia Alicia González-Martín Luis Almonacid Josefina Casas Gemma Fabriás Santos Mañes

Oncotarget 2013 Dec;4(12):2288-301

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December 2013

Anti-inflammatory action of lipid nanocarrier-delivered myriocin: therapeutic potential in cystic fibrosis.

Authors:
Anna Caretti Alessandra Bragonzi Marcella Facchini Ida De Fino Camilla Riva Paolo Gasco Claudia Musicanti Josefina Casas Gemma Fabriàs Riccardo Ghidoni Paola Signorelli

Biochim Biophys Acta 2014 Jan 18;1840(1):586-94. Epub 2013 Oct 18.

Department of Health Sciences, University of Milan, San Paolo Hospital, Italy.

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January 2014

Systemic ceramide accumulation leads to severe and varied pathological consequences.

Authors:
Abdulfatah M Alayoubi James C M Wang Bryan C Y Au Stéphane Carpentier Virginie Garcia Shaalee Dworski Samah El-Ghamrasni Kevin N Kirouac Mathilde J Exertier Zi Jian Xiong Gilbert G Privé Calogera M Simonaro Josefina Casas Gemma Fabrias Edward H Schuchman Patricia V Turner Razqallah Hakem Thierry Levade Jeffrey A Medin

EMBO Mol Med 2013 Jun 16;5(6):827-42. Epub 2013 May 16.

Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.

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June 2013

Straightforward access to spisulosine and 4,5-dehydrospisulosine stereoisomers: probes for profiling ceramide synthase activities in intact cells.

Authors:
José Luis Abad Ingrid Nieves Pedro Rayo Josefina Casas Gemma Fabriàs Antonio Delgado

J Org Chem 2013 Jun 30;78(12):5858-66. Epub 2013 May 30.

Consejo Superior de Investigaciones Científicas (CSIC), Institut de Química Avançada de Catalunya (IQAC-CSIC), Research Unit on Bioactive Molecules (RUBAM), Jordi Girona 18-26, 08034 Barcelona, Spain.

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June 2013

Specific sphingolipid content decrease in Cerkl knockdown mouse retinas.

Authors:
Alejandro Garanto Nawajes A Mandal Meritxell Egido-Gabás Gemma Marfany Gemma Fabriàs Robert E Anderson Josefina Casas Roser Gonzàlez-Duarte

Exp Eye Res 2013 May 15;110:96-106. Epub 2013 Mar 15.

Departament de Genètica, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain.

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May 2013

Acid ceramidase as a therapeutic target in metastatic prostate cancer.

Authors:
Luz Camacho Oscar Meca-Cortés José Luis Abad Simón García Nuria Rubio Alba Díaz Toni Celià-Terrassa Francesca Cingolani Raquel Bermudo Pedro L Fernández Jerónimo Blanco Antonio Delgado Josefina Casas Gemma Fabriàs Timothy M Thomson

J Lipid Res 2013 May 19;54(5):1207-20. Epub 2013 Feb 19.

Department of Biomedicinal Chemistry, Research Unit on Bioactive Molecules (RUBAM), Institute for Advanced Chemistry of Catalonia, National Research Council (IQAC-CSIC), Barcelona, Spain.

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May 2013

Natural products as platforms for the design of sphingolipid-related anticancer agents.

Authors:
Antonio Delgado Gemma Fabriàs Josefina Casas José Luis Abad

Adv Cancer Res 2013 ;117:237-81

Spanish National Research Council, Consejo Superior de Investigaciones Científicas, Research Unit on Bioactive Molecules, Jordi Girona 18-26, Barcelona, Spain.

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June 2013

The nonlysosomal β-glucosidase GBA2 promotes endoplasmic reticulum stress and impairs tumorigenicity of human melanoma cells.

Authors:
Sonia-Caroline Sorli Sandra Colié Virginie Albinet Alexandre Dubrac Christian Touriol Nicolas Guilbaud Carmen Bedia Gemma Fabriàs Josefina Casas Bruno Ségui Thierry Levade Nathalie Andrieu-Abadie

FASEB J 2013 Feb 16;27(2):489-98. Epub 2012 Oct 16.

Institut National de Santé et de Recherche Médicale (INSERM) Unité Mixte de Recherche 1037, Centre de Recherches en Cancérologie de Toulouse, Toulouse, France.

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February 2013

Fat necrosis generates proinflammatory halogenated lipids during acute pancreatitis.

Authors:
Neus Franco-Pons Josefina Casas Gemma Fabriàs Sabrina Gea-Sorlí Enrique de-Madaria Emilio Gelpí Daniel Closa

Ann Surg 2013 May;257(5):943-51

Department of Experimental Pathology, IIBB-CSIC, IDIBAPS and CIBEREHD, Barcelona, Spain.

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May 2013

Ceramide--antiestrogen nanoliposomal combinations--novel impact of hormonal therapy in hormone-insensitive breast cancer.

Authors:
Samy A F Morad Jonathan C Levin Sriram S Shanmugavelandy Mark Kester Gemma Fabrias Carmen Bedia Myles C Cabot

Mol Cancer Ther 2012 Nov 7;11(11):2352-61. Epub 2012 Sep 7.

Department of Experimental Therapeutics, John Wayne Cancer Institute, 2200 Santa Monica Blvd, Santa Monica, CA 90404, USA.

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November 2012

Dihydroceramide delays cell cycle G1/S transition via activation of ER stress and induction of autophagy.

Authors:
Vincenzo Gagliostro Josefina Casas Anna Caretti Jose L Abad Luigina Tagliavacca Riccardo Ghidoni Gemma Fabrias Paola Signorelli

Int J Biochem Cell Biol 2012 Dec 7;44(12):2135-43. Epub 2012 Sep 7.

Lab. Biochemistry & Molecular Biology, San Paolo Hospital, Medical School, University of Milan, Via A. di Rudinì 8, 20142 Milan, Italy.

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December 2012

Cellular changes that accompany shedding of human corneocytes.

Authors:
Tzu-Kai Lin Debra Crumrine Larry D Ackerman Juan-Luis Santiago Truus Roelandt Yoshikazu Uchida Melanie Hupe Gemma Fabriàs Jose L Abad Robert H Rice Peter M Elias

J Invest Dermatol 2012 Oct 28;132(10):2430-2439. Epub 2012 Jun 28.

Department of Veterans Affairs Medical Center and Department of Dermatology, Dermatology Service, University of California, San Francisco, San Francisco, California, USA. Electronic address:

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October 2012

Sialyllactose in viral membrane gangliosides is a novel molecular recognition pattern for mature dendritic cell capture of HIV-1.

Authors:
Nuria Izquierdo-Useros Maier Lorizate F-Xabier Contreras Maria T Rodriguez-Plata Bärbel Glass Itziar Erkizia Julia G Prado Josefina Casas Gemma Fabriàs Hans-Georg Kräusslich Javier Martinez-Picado

PLoS Biol 2012 24;10(4):e1001315. Epub 2012 Apr 24.

AIDS Research Institute IrsiCaixa, Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain.

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August 2012

3-Deoxy-3,4-dehydro analogs of XM462. Preparation and activity on sphingolipid metabolism and cell fate.

Authors:
Luz Camacho Fabio Simbari Maria Garrido José Luis Abad Josefina Casas Antonio Delgado Gemma Fabriàs

Bioorg Med Chem 2012 May 6;20(10):3173-9. Epub 2012 Apr 6.

Research Unit on Bioactive Molecules, Department of Biomedicinal Chemistry, Institute for Advanced Chemistry of Catalonia, Spanish Council for Scientific Research, Jordi Girona 18-26, 08034 Barcelona, Spain.

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May 2012

Fenretinide prevents lipid-induced insulin resistance by blocking ceramide biosynthesis.

Authors:
Benjamin T Bikman Yuguang Guan Guanghou Shui M Mobin Siddique William L Holland Ji Yun Kim Gemma Fabriàs Markus R Wenk Scott A Summers

J Biol Chem 2012 May 2;287(21):17426-37. Epub 2012 Apr 2.

Department of Physiology and Developmental Biology, Brigham Young University, Provo, Utah 84602, USA.

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May 2012

Sphingosine mediates TNFα-induced lysosomal membrane permeabilization and ensuing programmed cell death in hepatoma cells.

Authors:
Chiara Ullio Josefina Casas Ulf T Brunk Giuseppina Sala Gemma Fabriàs Riccardo Ghidoni Gabriella Bonelli Francesco M Baccino Riccardo Autelli

J Lipid Res 2012 Jun 27;53(6):1134-43. Epub 2012 Mar 27.

Department of Experimental Medicine and Oncology, University of Turin, Turin, Italy.

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June 2012

Determination of sphingosine-1-phosphate lyase activity by gas chromatography coupled to electron impact mass spectrometry.

Authors:
Ester Reina Luz Camacho Josefina Casas Paul P Van Veldhoven Gemma Fabrias

Chem Phys Lipids 2012 Feb 12;165(2):225-31. Epub 2012 Jan 12.

Dept. of Biomedicinal Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC), Spanish National Research Council (CSIC), Barcelona, Spain.

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February 2012

Dihydroceramide desaturase and dihydrosphingolipids: debutant players in the sphingolipid arena.

Authors:
Gemma Fabrias Jose Muñoz-Olaya Francesca Cingolani Paola Signorelli Josefina Casas Vincenzo Gagliostro Riccardo Ghidoni

Prog Lipid Res 2012 Apr 17;51(2):82-94. Epub 2011 Dec 17.

Dept. of Biomedicinal Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC), Spanish Council for Scientific Research (CSIC), 08034 Barcelona, Spain.

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April 2012

C6-ceramide and targeted inhibition of acid ceramidase induce synergistic decreases in breast cancer cell growth.

Authors:
Margaret Flowers Gemma Fabriás Antonio Delgado Josefina Casas Jose Luis Abad Myles C Cabot

Breast Cancer Res Treat 2012 Jun 21;133(2):447-58. Epub 2011 Sep 21.

Department of Experimental Therapeutics, John Wayne Cancer Institute, Santa Monica, CA, USA.

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June 2012

Sphingolipid modulation: a strategy for cancer therapy.

Authors:
Antonio Delgado Gemma Fabrias Carmen Bedia Josefina Casas Jose Luis Abad

Anticancer Agents Med Chem 2012 May;12(4):285-302

Spanish National Research Council (Consejo Superior de Investigaciones Científicas, CSIC), Research Unit on Bioactive Molecules (RUBAM), Barcelona, Spain.

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May 2012

Ceramidases in hematological malignancies: senseless or neglected target?

Authors:
Gemma Fabrias Carmen Bedia Josefina Casas Jose Luis Abad Antonio Delgado

Anticancer Agents Med Chem 2011 Nov;11(9):830-43

Spanish National Research Council, Research Unit on Bioactive Molecules, Departament de Química Biomèdica, Institut de Química Avançada de Catalunya, Barcelona, Spain.

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November 2011

Acid ceramidase expression modulates the sensitivity of A375 melanoma cells to dacarbazine.

Authors:
Carmen Bedia Josefina Casas Nathalie Andrieu-Abadie Gemma Fabriàs Thierry Levade

J Biol Chem 2011 Aug 23;286(32):28200-9. Epub 2011 Jun 23.

INSERM UMR 1037, CHU Rangueil, BP 84225, Toulouse 31432 Cedex 4, France.

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August 2011

Inhibition of acid ceramidase by a 2-substituted aminoethanol amide synergistically sensitizes prostate cancer cells to N-(4-hydroxyphenyl) retinamide.

Authors:
Valérie Gouazé-Andersson Margaret Flowers Ramin Karimi Gemma Fabriás Antonio Delgado Josefina Casas Myles C Cabot

Prostate 2011 Jul 28;71(10):1064-73. Epub 2010 Dec 28.

John Wayne Cancer Institute, Santa Monica, California 90404, USA.

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July 2011

A simple fluorogenic method for determination of acid ceramidase activity and diagnosis of Farber disease.

Authors:
Carmen Bedia Luz Camacho José Luís Abad Gemma Fabriàs Thierry Levade

J Lipid Res 2010 Dec 24;51(12):3542-7. Epub 2010 Sep 24.

INSERM, U858, Toulouse, France.

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December 2010

Dihydrosphingomyelin impairs HIV-1 infection by rigidifying liquid-ordered membrane domains.

Authors:
Catarina R Vieira Jose M Munoz-Olaya Jesús Sot Sonia Jiménez-Baranda Nuria Izquierdo-Useros Jose Luis Abad Beatriz Apellániz Rafael Delgado Javier Martinez-Picado Alicia Alonso Josefina Casas José L Nieva Gemma Fabriás Santos Mañes Félix M Goñi

Chem Biol 2010 Jul;17(7):766-75

Department of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Darwin 3, E-28049 Madrid, Spain.

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July 2010

Glucosylceramide synthesis inhibition affects cell cycle progression, membrane trafficking, and stage differentiation in Giardia lamblia.

Authors:
Sasa Stefanić Cornelia Spycher Laura Morf Gemma Fabriàs Josefina Casas Elisabeth Schraner Peter Wild Adrian B Hehl Sabrina Sonda

J Lipid Res 2010 Sep 24;51(9):2527-45. Epub 2010 Mar 24.

Institute of Parasitology, University of Zurich, Zurich, Switzerland.

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September 2010

Control of metabolism and signaling of simple bioactive sphingolipids: Implications in disease.

Authors:
Patricia Gangoiti Luz Camacho Lide Arana Alberto Ouro Maria H Granado Leyre Brizuela Josefina Casas Gemma Fabriás José Luis Abad Antonio Delgado Antonio Gómez-Muñoz

Prog Lipid Res 2010 Oct 1;49(4):316-34. Epub 2010 Mar 1.

Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Bilbao, Spain.

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October 2010

cis- versus trans-ceramides: effects of the double bond on conformation and H-bonding interactions.

Authors:
Shay C Phillips Gemma Triola Gemma Fabrias Félix M Goñi Donald B DuPré M Cecilia Yappert

J Phys Chem B 2009 Nov;113(46):15249-55

Department of Chemistry, University of Louisville, Louisville, Kentucky 40292, USA.

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November 2009

Dihydroceramide intracellular increase in response to resveratrol treatment mediates autophagy in gastric cancer cells.

Authors:
Paola Signorelli Jose M Munoz-Olaya Vincenzo Gagliostro Josefina Casas Riccardo Ghidoni Gemma Fabriàs

Cancer Lett 2009 Sep 25;282(2):238-43. Epub 2009 Apr 25.

Laboratory of Biochemistry and Molecular Biology, San Paolo University Hospital, Medical School, University of Milan, Italy.

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September 2009

Host cell P-glycoprotein is essential for cholesterol uptake and replication of Toxoplasma gondii.

Authors:
Iveta Bottova Adrian B Hehl Sasa Stefanić Gemma Fabriàs Josefina Casas Elisabeth Schraner Jean Pieters Sabrina Sonda

J Biol Chem 2009 Jun 22;284(26):17438-48. Epub 2009 Apr 22.

Institute of Parasitology, University of Zurich, Zurich, Switzerland.

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June 2009

Synthesis of a fluorogenic analogue of sphingosine-1-phosphate and its use to determine sphingosine-1-phosphate lyase activity.

Authors:
Carmen Bedia Luz Camacho Josefina Casas José Luis Abad Antonio Delgado Paul P Van Veldhoven Gemma Fabriàs

Chembiochem 2009 Mar;10(5):820-2

Department of Biomedicinal Chemistry, Institut de Química Avançada de Catalunya, CSIC, Jordi Girona 18, 08034 Barcelona, Spain.

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March 2009

Synthesis and biological properties of Pachastrissamine (jaspine B) and diastereoisomeric jaspines.

Authors:
Daniel Canals David Mormeneo Gemma Fabriàs Amadeu Llebaria Josefina Casas Antonio Delgado

Bioorg Med Chem 2009 Jan 18;17(1):235-41. Epub 2008 Nov 18.

Research Unit on BioActive Molecules (RUBAM), Departament de Química Biomèdica, Institut de Química Avançada de Catalunya (IQAC-C.S.I.C), Jordi Girona 18-26, 08034 Barcelona, Spain.

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January 2009

Cytotoxicity and acid ceramidase inhibitory activity of 2-substituted aminoethanol amides.

Authors:
Carmen Bedia Daniel Canals Xavier Matabosch Youssef Harrak Josefina Casas Amadeu Llebaria Antonio Delgado Gemma Fabriás

Chem Phys Lipids 2008 Nov 8;156(1-2):33-40. Epub 2008 Aug 8.

Research Unit on BioActive Molecules (RUBAM), Departament de Química Biomèdica, Institut de Química Avançada de Catalunya IQAC-CSIC, Jordi Girona 18-26, Barcelona, Spain.

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November 2008

Synthesis and biological activity of a novel inhibitor of dihydroceramide desaturase.

Authors:
Jose M Munoz-Olaya Xavier Matabosch Carmen Bedia Meritxell Egido-Gabás Josefina Casas Amadeu Llebaria Antonio Delgado Gemma Fabriàs

ChemMedChem 2008 Jun;3(6):946-53

Research Unit on BioActive Molecules, Departamento de Química Orgánica Biológica, Instituto de Investigaciones Químicas y Ambientales de Barcelona, CSIC, Jordi Girona 18, 08034 Barcelona, Spain.

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June 2008

Substrate-dependent stereochemical course of the (Z)-13-desaturation catalyzed by the processionary moth multifunctional desaturase.

Authors:
José-Luis Abad Francisco Camps Gemma Fabriàs

J Am Chem Soc 2007 Dec 9;129(48):15007-12. Epub 2007 Nov 9.

Departamento de Química OrgAnica Biológica, Instituto de Investigaciones Químicas y Ambientales de Barcelona, Consejo Superior de Investigaciones Científicas, 08034 Barcelona, Spain.

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December 2007

A multifunctional desaturase involved in the biosynthesis of the processionary moth sex pheromone.

Authors:
Montserrat Serra Benjamin Piña José Luis Abad Francisco Camps Gemma Fabriàs

Proc Natl Acad Sci U S A 2007 Oct 5;104(42):16444-9. Epub 2007 Oct 5.

Research Unit on BioActive Molecules (RUBAM), Departament de Química Orgànica Biològica, Institut d'Investigacions Químiques i Ambientals de Barcelona, Consejo Superior de Investigaciones Científicas (CSIC), Barcelona, Spain.

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October 2007

Synthesis of a novel ceramide analogue and its use in a high-throughput fluorogenic assay for ceramidases.

Authors:
Carmen Bedia Josefina Casas Virginie Garcia Thierry Levade Gemma Fabriàs

Chembiochem 2007 Apr;8(6):642-8

Research Unit on BioActive Molecules, Departamento de Química Orgánica Biológica, Instituto de Investigaciones Químicas y Ambientales de Barcelona, CSIC, Jordi Girona 18, 08034 Barcelona, Spain.

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April 2007

Synthesis and use of deuterated palmitic acids to decipher the cryptoregiochemistry of a Delta13 desaturation.

Authors:
José-Luis Abad Montserrat Serra Francisco Camps Gemma Fabriàs

J Org Chem 2007 Feb;72(3):760-4

Departamento de Química OrgAnica Biológica, Instituto de Investigaciones Químicas y Ambientales de Barcelona, Consejo Superior de Investigaciones Científicas, J. Girona 18, 08034, Barcelona, Spain.

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February 2007

Chemical tools to investigate sphingolipid metabolism and functions.

Authors:
Antonio Delgado Josefina Casas Amadeu Llebaria José Luis Abad Gemma Fabriás

ChemMedChem 2007 May;2(5):580-606

Research Unit on Bioactive Molecules, Departament de Química Orgànica Biològica, Institut d'Investigacions Químiques i Ambientals de Barcelona (C.S.I.C); Jordi Girona 18-26, 08034 Barcelona, Spain.

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May 2007

Solid-phase synthesis of a combinatorial library of dihydroceramide analogues and its activity in human alveolar epithelial cells.

Authors:
Gemma Villorbina Daniel Canals Lydia Carde Santiago Grijalvo Rosalia Pascual Obdulia Rabal Jordi Teixidó Gemma Fabriàs Amadeu Llebaria Josefina Casas Antonio Delgado

Bioorg Med Chem 2007 Jan 17;15(1):50-62. Epub 2006 Oct 17.

Research Unit on BioActive Molecules (RUBAM), Departament de Química Orgànica Biològica, Institut d'Investigacions Químiques i Ambientals de Barcelona (IIQAB-C.S.I.C), Jordi Girona 18-26, 08034 Barcelona, Spain.

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January 2007

Inhibitors of sphingolipid metabolism enzymes.

Authors:
Antonio Delgado Josefina Casas Amadeu Llebaria José Luís Abad Gemma Fabrias

Biochim Biophys Acta 2006 Dec 1;1758(12):1957-77. Epub 2006 Sep 1.

Research Unit on Bioactive Molecules (RUBAM), Department of Biological Organic Chemistry, Chemical and Environmental Research Institute of Barcelona, (IIQAB-C.S.I.C), Jordi Girona 18-26, 08034 Barcelona, Spain.

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December 2006

Delta11 desaturases of Trichoplusia ni and Spodoptera littoralis exhibit dual catalytic behaviour.

Authors:
Montserrat Serra Lewis T Gauthier Gemma Fabrias Peter H Buist

Insect Biochem Mol Biol 2006 Oct 22;36(10):822-5. Epub 2006 Aug 22.

Department of Biological Organic Chemistry, IIQAB-CSIC, Jordi Girona 18, 08034 Barcelona, Spain.

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October 2006

Synthesis and use of probes to investigate the cryptoregiochemistry of the first animal acetylenase.

Authors:
José-Luis Abad Sergio Rodríguez Francisco Camps Gemma Fabriàs

J Org Chem 2006 Sep;71(20):7558-64

Departamento de Química Organica Biológica, Instituto de Investigaciones Químicas y Ambientales de Barcelona, Consejo Superior de Investigaciones Científicas, 08034, Barcelona, Spain.

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September 2006

Design, synthesis and activity as acid ceramidase inhibitors of 2-oxooctanoyl and N-oleoylethanolamine analogues.

Authors:
Santiago Grijalvo Carmen Bedia Gemma Triola Josefina Casas Amadeu Llebaria Jordi Teixidó Obdulia Rabal Thierry Levade Antonio Delgado Gemma Fabriàs

Chem Phys Lipids 2006 Oct 7;144(1):69-84. Epub 2006 Aug 7.

Research Unit on Bioactive Molecules (RUBAM), Departament de Química Orgànica Biològica, Institut d'Investigacions Químiques i Ambientals de Barcelona (IIQAB-CSIC), Jordi Girona 18-26, E-08034 Barcelona, Spain.

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October 2006

Biosynthesis of 10,12-dienoic fatty acids by a bifunctional Delta11 desaturase in Spodoptera littoralis.

Authors:
Montserrat Serra Benjami Piña Jordi Bujons Francisco Camps Gemma Fabriàs

Insect Biochem Mol Biol 2006 Aug 20;36(8):634-41. Epub 2006 May 20.

Department of Biological Organic Chemistry, IIQAB-CSIC, Jordi Girona 18, 08034 Barcelona, Spain.

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August 2006

Analogs of the dihydroceramide desaturase inhibitor GT11 modified at the amide function: synthesis and biological activities.

Authors:
Carmen Bedia Gemma Triola Josefina Casas Amadeu Llebaria Gemma Fabriàs

Org Biomol Chem 2005 Oct 8;3(20):3707-12. Epub 2005 Sep 8.

Research Unit on BioActive Molecules (RUBAM), Department of Biological Organic Chemistry, Instituto de Investigaciones Químicas y Ambientales de Barcelona (IIQAB), CSIC Jordi Girona 18, 08034, Barcelona, Spain.

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October 2005

Expression and evolution of delta9 and delta11 desaturase genes in the moth Spodoptera littoralis.

Authors:
Sergio Rodríguez Guixia Hao Weitian Liu Benjamín Piña Alejandro P Rooney Francisco Camps Wendell L Roelofs Gemma Fabriàs

Insect Biochem Mol Biol 2004 Dec;34(12):1315-28

Department of Biological Organic Chemistry, IIQAB-CSIC, IBMB-CSIC, Jordi Girona 18, 08034 Barcelona, Spain.

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December 2004

Synthesis and use of stereospecifically deuterated analogues of palmitic Acid to investigate the stereochemical course of the delta11 desaturase of the processionary moth.

Authors:
José-Luis Abad Gemma Villorbina Gemma Fabriàs Francisco Camps

J Org Chem 2004 Oct;69(21):7108-13

Departamento de Química Orgánica Biológica, Instituto de Investigaciones Químicas y Ambientales de Barcelona, Consejo Superior de Investigaciones Científicas, 08034, Barcelona, Spain.

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October 2004

Specificity of the dihydroceramide desaturase inhibitor N-[(1R,2S)-2-hydroxy-1-hydroxymethyl-2-(2-tridecyl-1-cyclopropenyl)ethyl]octanamide (GT11) in primary cultured cerebellar neurons.

Authors:
Gemma Triola Gemma Fabrias Mihaela Dragusin Lars Niederhausen Roland Broere Amadeu Llebaria Gerhild van Echten-Deckert

Mol Pharmacol 2004 Dec 15;66(6):1671-8. Epub 2004 Sep 15.

Research Unit on Bioactive Molecules, Department of Biological Organic Chemistry, Institut d'Investigacions Químiques i Ambientals de Barcelona, Consejo Superior de Investigaciones, Cientificas, Barcelona, Spain.

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December 2004

Synthesis of deuterated fatty acids to investigate the biosynthetic pathway of disparlure, the sex pheromone of the gypsy moth, Lymantria dispar.

Authors:
José-Luis Abad Gemma Fabriàs Francisco Camps

Lipids 2004 Apr;39(4):397-401

Departamento de Química Orgánica Biológica, Instituto de Investigaciones Químicas y Ambientales de Barcelona, Consejo Superior de Investigaciones Científicas, 08034-Barcelona, Spain.

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April 2004

Inhibition of the acyl-CoA desaturases involved in the biosynthesis of Spodoptera littoralis sex pheromone by analogs of 10,11-methylene-10-tetradecenoic acid.

Authors:
Sergio Rodríguez Francisco Camps Gemma Fabriàs

Insect Biochem Mol Biol 2004 Mar;34(3):283-9

Departamento de Química Orgánica Biológica, Instituto de Investigaciones Químicas y Ambientales de Barcelona, CSIC, Jordi Girona 18, 08034 Barcelona, Spain.

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March 2004

Synthesis of cyclopropene analogues of ceramide and their effect on dihydroceramide desaturase.

Authors:
Gemma Triola Gemma Fabriàs Josefina Casas Amadeu Llebaria

J Org Chem 2003 Dec;68(26):9924-32

RUBAM (Research Unit on BioActive Molecules), Department of Biological Organic Chemistry, IIQAB-CSIC, Jordi Girona 18-26, 08034 Barcelona, Spain.

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December 2003

Synthesis of fluorinated analogs of myristic acid as potential inhibitors of Egyptian armyworm (Spodoptera littoralis) delta11 desaturase.

Authors:
José-Luis Abad Gemma Villorbina Gemma Fabriàs Francisco Camps

Lipids 2003 Aug;38(8):865-71

Departamento de Química Orgánica Biológica, Instituto de Investigaciones Químicas y Ambientales de Barcelona, Consejo Superior de Investigaciones Científicas, 08034, Barcelona, Spain.

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August 2003

Enzymatic desaturation of fatty acids: delta11 desaturase activity on cyclopropane acid probes.

Authors:
Gemma Villorbina Lidia Roura Francisco Camps Jesús Joglar Gemma Fabriàs

J Org Chem 2003 Apr;68(7):2820-9

Departamento de Química Orgánica Biológica, Instituto de Investigaciones Químicas y Ambientales de Barcelona, Consejo Superior de Investigaciones Científicas, Jordi Girona 18-26, 08034 Barcelona, Spain.

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April 2003

Sex pheromone biosynthetic pathway for disparlure in the gypsy moth, Lymantria dispar.

Authors:
Russell A Jurenka Mitko Subchev Jose-Luis Abad Man-Yeon Choi Gemma Fabrias

Proc Natl Acad Sci U S A 2003 Feb 17;100(3):809-14. Epub 2003 Jan 17.

Department of Entomology, 407 Science II, Iowa State University, Ames, IA 50011-3222, USA.

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February 2003

A new member of the PBAN family in Spodoptera littoralis: molecular cloning and immunovisualisation in scotophase hemolymph.

Authors:
Francesc Iglesias Pilar Marco Marie-Christine François Francisco Camps Gemma Fabriàs Emmanuelle Jacquin-Joly

Insect Biochem Mol Biol 2002 Aug;32(8):901-8

Department of Biological Organic Chemistry, IIQAB, CSIC, Jordi Girona 18-26, E-08034 Barcelona, Spain.

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August 2002

Stereospecificity of an enzymatic monoene 1,4-dehydrogenation reaction: conversion of (Z)-11-tetradecenoic acid into (E,E)-10,12-tetradecadienoic acid.

Authors:
Sergio Rodríguez Pere Clapés Francisco Camps Gemma Fabriàs

J Org Chem 2002 Apr;67(7):2228-33

Department of Biological Organic Chemistry and Deparment of Peptide and Protein Chemistry, IIQAB-CSIC, Jordi Girona 18-26, 08034-Barcelona, Spain.

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April 2002

Synthesis of a Cyclopropene Analogue of Ceramide, a Potent Inhibitor of Dihydroceramide Desaturase This work was supported by the Dirección General de Enseñanza Superior e Investigación Científica (grant PB97-1171) and the Departament d'Universitats, Recerca i Societat de la Informació, Generalitat de Catalunya (grant 1999-SGR 00187 and a Predoctoral fellowship to G.T.). We thank Dr. J. Casas, Dr. A. Delgado, and Dr. J. Joglar for their help in different aspects of this work.

Authors:
Gemma Triola Gemma Fabriàs Amadeu Llebaria

Angew Chem Int Ed Engl 2001 May;40(10):1960-1962

Department of Biological Organic Chemistry (IIQAB-CSIC) Jordi Girona 18-26, 08034-Barcelona (Spain).

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May 2001