Geert Jan Biessels

Geert Jan Biessels

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Geert Jan Biessels

Publications by authors named "Geert Jan Biessels"

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Oxidative stress and endothelial dysfunction are associated with reduced cognition in type 2 diabetes.

Diab Vasc Dis Res 2019 Nov 9;16(6):577-581. Epub 2019 May 9.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1177/1479164119848093DOI Listing
November 2019

Frequent Cognitive Impairment in Patients With Disorders Along the Heart-Brain Axis.

Stroke 2019 Nov 5:STROKEAHA119026031. Epub 2019 Nov 5.

From the Department of Neurology, Alzheimer Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, location VUmc, the Netherlands (A.M.H., A.E.L., W.M.v.d.F.).

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http://dx.doi.org/10.1161/STROKEAHA.119.026031DOI Listing
November 2019

High-Normal Adolescent Fasting Plasma Glucose Is Associated With Poorer Midlife Brain Health: Bogalusa Heart Study.

J Clin Endocrinol Metab 2019 Oct;104(10):4492-4500

Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.

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http://dx.doi.org/10.1210/jc.2018-02750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736207PMC
October 2019

Assessment of the appropriate use criteria for amyloid PET in an unselected memory clinic cohort: The ABIDE project.

Alzheimers Dement 2019 Oct 6. Epub 2019 Oct 6.

Department of Neurology, Amsterdam Neuroscience, Alzheimer Center, VU University, Amsterdam UMC, Amsterdam, the Netherlands; Department of Epidemiology and Biostatistics, Amsterdam Neuroscience, VU University of Amsterdam, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.jalz.2019.07.003DOI Listing
October 2019

Nonfocal Transient Neurological Attacks Are Associated With Cerebral Small Vessel Disease.

Stroke 2019 Oct 22:STROKEAHA119025328. Epub 2019 Oct 22.

From the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, the Netherlands (E.A.O., G.J.B., L.J.K.).

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http://dx.doi.org/10.1161/STROKEAHA.119.025328DOI Listing
October 2019

Occurrence of Impaired Physical Performance in Memory Clinic Patients With Cerebral Small Vessel Disease.

Alzheimer Dis Assoc Disord 2018 Jul-Sep;32(3):214-219

Department of Geriatrics, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1097/WAD.0000000000000233DOI Listing
September 2019

Physical Performance in Memory Clinic Patients: The Potential Role of the White Matter Network.

J Am Geriatr Soc 2019 Sep 28;67(9):1880-1887. Epub 2019 May 28.

Department of Neurology, Neurosurgery, and Neuropsychology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jgs.15987
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http://dx.doi.org/10.1111/jgs.15987DOI Listing
September 2019

Reply to: Comment on Physical Performance in Memory Clinic Patients: The Potential Role of the White Matter Network.

J Am Geriatr Soc 2019 Sep 13. Epub 2019 Sep 13.

Department of Neurology, Neurosurgery, and Neuropsychology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1111/jgs.16160DOI Listing
September 2019

Cortical microinfarcts in memory clinic patients are associated with reduced cerebral perfusion.

J Cereb Blood Flow Metab 2019 Sep 26:271678X19877403. Epub 2019 Sep 26.

Memory Aging and Cognition Centre, Department of Pharmacology, National University of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1177/0271678X19877403DOI Listing
September 2019

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping.

J Vis Exp 2019 Sep 25(151). Epub 2019 Sep 25.

Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University.

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http://dx.doi.org/10.3791/59653DOI Listing
September 2019

Hippocampal sulcal cavities: prevalence, risk factors and association with cognitive performance. The SMART-Medea study and PREDICT-MR study.

Brain Imaging Behav 2019 Aug;13(4):1093-1102

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6.131, P.O. Box 85500, 3508, GA, Utrecht, the Netherlands.

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http://dx.doi.org/10.1007/s11682-018-9916-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647498PMC
August 2019

Nonfocal transient neurological attacks are related to cognitive impairment in patients with heart failure.

J Neurol 2019 Aug 21;266(8):2035-2042. Epub 2019 May 21.

Department of Neurology and Neurosurgery, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s00415-019-09376-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647193PMC
August 2019

Cerebral Perfusion and the Occurrence of Nonfocal Transient Neurological Attacks.

Cerebrovasc Dis 2019 16;47(5-6):303-308. Epub 2019 Aug 16.

Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1159/000502334DOI Listing
August 2019

Impact of white matter hyperintensity location on depressive symptoms in memory-clinic patients: a lesion–symptom mapping study

J Psychiatry Neurosci 2019 07;44(4):E1-E10

From the Alzheimer Centre Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands (Leeuwis, Hooghiemstra, Prins, Scheltens, van der Flier); the Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht, the Netherlands (Weaver, Biesbroek, Exalto, Biessels); the Image Sciences Institute, University Medical Centre Utrecht, Utrecht, the Netherlands (Kuijf); the Department of Medical Humanities, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (Hooghiemstra); the Institutes of Neurology and Healthcare Engineering, UCL, London, United Kingdom (Barkhof); the Department of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (Barkhof); and the Department of Epidemiology & Biostatistics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (Flier).

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http://dx.doi.org/10.1503/jpn.180136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606429PMC
July 2019

Subjective cognitive decline, brain imaging biomarkers, and cognitive functioning in patients with a history of vascular disease: the SMART-Medea study.

Neurobiol Aging 2019 Jul 24;84:33-40. Epub 2019 Jul 24.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht and Utrecht University, Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.07.011DOI Listing
July 2019

Cortical Microinfarcts and White Matter Connectivity in Memory Clinic Patients.

Front Neurol 2019 5;10:571. Epub 2019 Jun 5.

Brain Center, University Medical Center Utrecht, Department of Neurology, University Medical Center Utrecht, University Utrecht, Utrecht, Netherlands.

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http://dx.doi.org/10.3389/fneur.2019.00571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560058PMC
June 2019

Clinical relevance of acute cerebral microinfarcts in vascular cognitive impairment.

Neurology 2019 Apr 8;92(14):e1558-e1566. Epub 2019 Mar 8.

From the Department of Neurology (D.A.F., H.v.d.B., L.G.E., J.M.F.B., G.J.B.), Brain Center UMC Utrecht, University Medical Center Utrecht, Utrecht University; Department of Neurology (J.M.F.B.), Onze Lieve Vrouwe Gasthuis (OLVG) West; Department of Radiology & Nuclear Medicine (F.B.) Department of Neurology and Alzheimer Center Amsterdam (N.D.P., W.M.v.d.F.), Department of Epidemiology & Biostatistics (W.M.v.d.F.), Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, the Netherlands; and Institutes of Neurology and Healthcare Engineering (F.B.), University College London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000007250DOI Listing
April 2019

White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities.

Alzheimers Dement (N Y) 2019 9;5:107-117. Epub 2019 Apr 9.

Molecular & Clinical Sciences Research Institute, St George's University of London and Department of Neurology, St George's University Hospitals NHS Foundation Trust, London, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S23528737193000
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http://dx.doi.org/10.1016/j.trci.2019.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461571PMC
April 2019

People with type 2 diabetes and screen-detected cognitive impairment use acute health care services more often: observations from the COG-ID study.

Diabetol Metab Syndr 2019 22;11:21. Epub 2019 Feb 22.

1Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1186/s13098-019-0416-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387554PMC
February 2019

The cumulative effect of small vessel disease lesions is reflected in structural brain networks of memory clinic patients.

Neuroimage Clin 2018 19;19:963-969. Epub 2018 Jun 19.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S22131582183020
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http://dx.doi.org/10.1016/j.nicl.2018.06.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039838PMC
January 2019

Vascular dysfunction-The disregarded partner of Alzheimer's disease.

Alzheimers Dement 2019 01;15(1):158-167

Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Alzheimer's Disease Research Center, Keck School of Medicine at the University of Southern California, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.07.222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338083PMC
January 2019

The Clinical Phenotype of Vascular Cognitive Impairment in Patients with Type 2 Diabetes Mellitus.

J Alzheimers Dis 2019 ;68(1):311-322

Department of Neurology, Brain Center Rudolph Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.3233/JAD-180914DOI Listing
January 2019

Depressive symptoms and quality of life after screening for cognitive impairment in patients with type 2 diabetes: observations from the Cog-ID cohort study.

BMJ Open 2019 01 17;9(1):e024696. Epub 2019 Jan 17.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1136/bmjopen-2018-024696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340460PMC
January 2019

HbA, Insulin Resistance, and β-Cell Function in Relation to Cognitive Function in Type 2 Diabetes: The CAROLINA Cognition Substudy.

Diabetes Care 2019 01;42(1):e1-e3

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.2337/DC18-0914DOI Listing
January 2019

Higher Pulsatility in Cerebral Perforating Arteries in Patients With Small Vessel Disease Related Stroke, a 7T MRI Study.

Stroke 2018 Dec 11:STROKEAHA118022516. Epub 2018 Dec 11.

Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, The Netherlands (C.J.M.K., G.J.B.).

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http://dx.doi.org/10.1161/STROKEAHA.118.022516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314503PMC
December 2018

Parietal Involvement in Constructional Apraxia as Measured Using the Pentagon Copying Task.

Dement Geriatr Cogn Disord 2018 24;46(1-2):50-59. Epub 2018 Aug 24.

Department of Neurology, Erasmus MC University Medical Centre, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1159/000491634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187841PMC
November 2018

HbA, Insulin Resistance, and β-Cell Function in Relation to Cognitive Function in Type 2 Diabetes: The CAROLINA Cognition Substudy.

Diabetes Care 2018 Nov 19. Epub 2018 Nov 19.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.2337/dc18-0914DOI Listing
November 2018

Cognitive decline and dementia in diabetes mellitus: mechanisms and clinical implications.

Nat Rev Endocrinol 2018 10;14(10):591-604

Department of Pharmacology and Nutritional Sciences and Department of Neurology, University of Kentucky, Lexington, KY, USA.

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http://dx.doi.org/10.1038/s41574-018-0048-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397437PMC
October 2018

Microstructure of Strategic White Matter Tracts and Cognition in Memory Clinic Patients with Vascular Brain Injury.

Dement Geriatr Cogn Disord 2017 19;44(5-6):268-282. Epub 2018 Jan 19.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1159/000485376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972515PMC
September 2018

Carotid circumferential wall stress is not associated with cognitive performance among individuals in late middle age: The Maastricht Study.

Atherosclerosis 2018 09 4;276:15-22. Epub 2018 Jul 4.

Department of Internal Medicine, Maastricht University Medical Centre +, Maastricht, the Netherlands; CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, the Netherlands.

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.07.003DOI Listing
September 2018

Applicability of diagnostic constructs for cognitive impairment in patients with type 2 diabetes mellitus.

Diabetes Res Clin Pract 2018 Aug 24;142:92-99. Epub 2018 May 24.

University Medical Center Utrecht, Brain Center Rudolf Magnus, Department of Neurology, PO Box 85500, 3508 GA Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.diabres.2018.05.025DOI Listing
August 2018

Cortical Microinfarcts on 3T Magnetic Resonance Imaging in Cerebral Amyloid Angiopathy.

Stroke 2018 08;49(8):1899-1905

Department of Clinical Neurosciences (A.Z., A.R.S., A.C., B.G.G., C.R.M., E.E.S., R.F.).

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http://dx.doi.org/10.1161/STROKEAHA.118.020810DOI Listing
August 2018

Cortical Cerebral Microinfarcts on 3 Tesla MRI in Patients with Vascular Cognitive Impairment.

J Alzheimers Dis 2017 ;60(4):1443-1450

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, The Netherlands.

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http://dx.doi.org/10.3233/JAD-170481DOI Listing
July 2018

Free water determines diffusion alterations and clinical status in cerebral small vessel disease.

Alzheimers Dement 2018 06 16;14(6):764-774. Epub 2018 Feb 16.

Institute for Stroke and Dementia Research, University Hospital, LMU Munich, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.

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http://dx.doi.org/10.1016/j.jalz.2017.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994358PMC
June 2018

White matter hyperintensity shape and location feature analysis on brain MRI; proof of principle study in patients with diabetes.

Sci Rep 2018 01 30;8(1):1893. Epub 2018 Jan 30.

Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/s41598-018-20084-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789823PMC
January 2018

How to choose the most appropriate cognitive test to evaluate cognitive complaints in primary care.

BMC Fam Pract 2017 Dec 16;18(1):101. Epub 2017 Dec 16.

Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1186/s12875-017-0675-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732477PMC
December 2017

Detection, risk factors, and functional consequences of cerebral microinfarcts.

Lancet Neurol 2017 09 14;16(9):730-740. Epub 2017 Jul 14.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(17)30196-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861500PMC
September 2017

Abnormalities of Cerebral Deep Medullary Veins on 7 Tesla MRI in Amnestic Mild Cognitive Impairment and Early Alzheimer's Disease: A Pilot Study.

J Alzheimers Dis 2017 ;57(3):705-710

Brain Center Rudolf Magnus, Department of Neurology, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.3233/JAD-160952DOI Listing
August 2017

Brain microvascular injury and white matter disease provoked by diabetes-associated hyperamylinemia.

Ann Neurol 2017 Aug 29;82(2):208-222. Epub 2017 Jul 29.

Department of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, KY.

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http://dx.doi.org/10.1002/ana.24992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568970PMC
August 2017

Insulin resistance and cognitive performance in type 2 diabetes - The Maastricht study.

J Diabetes Complications 2017 May 12;31(5):824-830. Epub 2017 Feb 12.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1016/j.jdiacomp.2017.01.020DOI Listing
May 2017

Rule induction performance in amnestic mild cognitive impairment and Alzheimer's dementia: examining the role of simple and biconditional rule learning processes.

J Clin Exp Neuropsychol 2017 Apr 12;39(3):231-241. Epub 2016 Sep 12.

d Department of Neurology, Brain Center Rudolf Magnus , University Medical Center , Utrecht , the Netherlands.

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http://dx.doi.org/10.1080/13803395.2016.1218444DOI Listing
April 2017

Lesion location and cognitive impact of cerebral small vessel disease.

Clin Sci (Lond) 2017 Apr;131(8):715-728

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands.

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http://dx.doi.org/10.1042/CS20160452DOI Listing
April 2017

Reduced vascular amyloid burden at microhemorrhage sites in cerebral amyloid angiopathy.

Acta Neuropathol 2017 03 22;133(3):409-415. Epub 2016 Oct 22.

Department of Neurology, J. Philip Kistler Stroke Research Center, Harvard Medical School, Massachusetts General Hospital, 175 Cambridge Street, Suite 300, Boston, MA, 02114, USA.

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http://link.springer.com/10.1007/s00401-016-1635-0
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http://dx.doi.org/10.1007/s00401-016-1635-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325834PMC
March 2017

Brain volume and cognitive function in patients with revascularized coronary artery disease.

Int J Cardiol 2017 Mar 21;230:80-84. Epub 2016 Dec 21.

Department of Intensive Care, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.ijcard.2016.12.079DOI Listing
March 2017

Chronic hyperglycemia is related to poor functional outcome after acute ischemic stroke.

Int J Stroke 2017 02 26;12(2):180-186. Epub 2016 Oct 26.

1 Department of Neurology and Neurosurgery, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1177/1747493016676619DOI Listing
February 2017

Alzheimer's biomarkers in daily practice (ABIDE) project: Rationale and design.

Alzheimers Dement (Amst) 2017 23;6:143-151. Epub 2017 Jan 23.

Department of Neurology & Alzheimer Center, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands; Department of Epidemiology and Biostatistics, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.dadm.2017.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318541PMC
January 2017

Microbleed and microinfarct detection in amyloid angiopathy: a high-resolution MRI-histopathology study.

Brain 2016 12 19;139(Pt 12):3151-3162. Epub 2016 Sep 19.

1 J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1093/brain/aww229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840880PMC
December 2016

Quantification of deep medullary veins at 7 T brain MRI.

Eur Radiol 2016 Oct 16;26(10):3412-8. Epub 2016 Feb 16.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s00330-016-4220-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021732PMC
October 2016

Perivascular spaces on 7 Tesla brain MRI are related to markers of small vessel disease but not to age or cardiovascular risk factors.

J Cereb Blood Flow Metab 2016 10 6;36(10):1708-1717. Epub 2016 May 6.

Brain Center Rudolf Magnus, Department of Neurology, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1177/0271678X16648970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076789PMC
October 2016

Carotid stiffness is associated with impairment of cognitive performance in individuals with and without type 2 diabetes. The Maastricht Study.

Atherosclerosis 2016 10 22;253:186-193. Epub 2016 Jul 22.

Department of Internal Medicine, Maastricht University Medical Centre +, Maastricht, The Netherlands; CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2016.07.912DOI Listing
October 2016

Risk Factors and Cognitive Relevance of Cortical Cerebral Microinfarcts in Patients With Ischemic Stroke or Transient Ischemic Attack.

Stroke 2016 10 18;47(10):2450-5. Epub 2016 Aug 18.

From the Department of Medicine and Therapeutics (Z.W., A.W., W.L., L.S., A.L., V.C.T.M.), Therese Pei Fong Chow Research Centre for Prevention of Dementia (A.W., L.S., V.C.T.M.), Lui Che Woo Institute of Innovative Medicine (A.W., L.S., V.C.T.M.), The Chinese University of Hong Kong, China; Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, China (Z.W.); Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands (S.J.v.V., G.J.B.); Institute of Neuroscience and the Second Affiliated Hospital of Guangzhou Medical University and Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, China (J.Y.); and Department of Neurology, Jinling Hospital, Nanjing University School of Medicine, China (Y.X.).

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http://dx.doi.org/10.1161/STROKEAHA.115.012278DOI Listing
October 2016

Microbleeds on MRI are associated with microinfarcts on autopsy in cerebral amyloid angiopathy.

Neurology 2016 Oct 9;87(14):1488-1492. Epub 2016 Sep 9.

From the Hemorrhagic Stroke Research Program (A.L., S.J.v.V., A.C., D.R., A.V., A.A., S.M.-R., E.M.G., S.M.G., A.V.), Department of Neurology, Massachusetts General Hospital Stroke Research Center, Harvard Medical School, Boston; Department of Neurology (S.J.v.V., G.J.B.), Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands; Department of Pathology (C.M.W.), New York University Langone Medical Center, New York University School of Medicine; Department of Medicine (D.R.), Faculty of Medicine, Naresuan University, Phitsanulok, Thailand; and C.S. Kubik Laboratory for Neuropathology (M.F.), Massachusetts General Hospital, Harvard Medical School, Boston.

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http://dx.doi.org/10.1212/WNL.0000000000003184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075970PMC
October 2016

Determinants of leptomeningeal collateral flow in stroke patients with a middle cerebral artery occlusion.

Neuroradiology 2016 Oct 20;58(10):969-977. Epub 2016 Jul 20.

Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, HP E01 132, 3584 CX, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s00234-016-1727-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069303PMC
October 2016

Cortical cerebral microinfarcts on 3T MRI: A novel marker of cerebrovascular disease.

Neurology 2016 Oct 2;87(15):1583-1590. Epub 2016 Sep 2.

From the Memory Ageing and Cognition Centre (S.H., M.A.S., Q.L.C., C.C., M.K.I.), National University Health System, Singapore; Department of Pharmacology (S.H., M.A.S., Q.L.C., C.C.), National University of Singapore; Department of Neurology (E.S., S.J.v.V., G.J.B., M.K.I.), Brain Center Rudolf Magnus, University Medical Center Utrecht; Departments of Radiology and Medical Informatics (H.V.) and Neurology and Epidemiology (M.K.I.), Erasmus University Medical Center, Rotterdam, the Netherlands; Singapore Eye Research Institute (C.-Y. Cheng, C.S., C.Y. Cheung, T.Y.W.), Singapore National Eye Center; Academic Medicine Research Institute (T.Y.W., M.K.I.), Duke-NUS Graduate Medical School; and Raffles Neuroscience Centre (N.V.), Raffles Hospital, Singapore.

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http://dx.doi.org/10.1212/WNL.0000000000003110DOI Listing
October 2016

The natural course of elevated levels of depressive symptoms in patients with vascular disease over eight years of follow-up. The SMART-Medea study.

J Affect Disord 2016 Sep 24;202:95-101. Epub 2016 May 24.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2016.05.050DOI Listing
September 2016

Third European Stroke Science Workshop.

Stroke 2016 07 9;47(7):e178-86. Epub 2016 Jun 9.

From the Institute for Stroke and Dementia Research, Klinikum der Universtität München, Ludwig-Maximilians University, Munich, Germany (M.D.); Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (M.D.); Institutd' Investigacions Biomèdiques de Barcelona (IIBB), Consejo Superior de Investigaciones Científicas (CSIC), Institutd' Investigacions Biomèdiques August Pi iSunyer (IDIBAPS), Barcelona, Spain (A.M.P.); Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands (G.J.B., B.v.d.W.); Centre for Clinical Brain Sciences, Division of Clinical Neurosciences, University of Edinburgh, Edinburgh, United Kingdom (C.S.); Department of Clinical Sciences, Neurology, Lund University, Lund, Sweden (B.N.); Institute of Cardiovascular & Medical Sciences, University of Glasgow, Glasgow, United Kingdom (K.L.); and Department of Neurology, Inselspital, University of Bern, Bern, Switzerland (H.P.M.).

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http://dx.doi.org/10.1161/STROKEAHA.116.013516DOI Listing
July 2016

Diagnosis and treatment of vascular damage in dementia.

Biochim Biophys Acta 2016 05 22;1862(5):869-77. Epub 2015 Nov 22.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center, Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2015.11.009DOI Listing
May 2016

Heterogeneous histopathology of cortical microbleeds in cerebral amyloid angiopathy.

Neurology 2016 Mar 3;86(9):867-71. Epub 2016 Feb 3.

From the Department of Neurology, Brain Center Rudolf Magnus (S.J.v.V., G.J.B., C.J.M.K.), and the Department of Pathology (A.J.M.R.), University Medical Center Utrecht; Department of Neurology, Donders Institute for Brain Cognition and Behaviour, Center for Neuroscience (C.J.M.K.), Radboud University Medical Center, Nijmegen; and Department of Pathology (A.J.M.R.), VU Medical Center, Amsterdam, the Netherlands.

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http://www.neurology.org/content/early/2016/02/03/WNL.000000
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http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000241
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http://dx.doi.org/10.1212/WNL.0000000000002419DOI Listing
March 2016

Peripheral glucose levels and cognitive outcome after ischemic stroke-Results from the Munich Stroke Cohort.

Eur Stroke J 2016 Mar 1;1(1):51-60. Epub 2016 Mar 1.

Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, Germany.

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http://dx.doi.org/10.1177/2396987316631674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301221PMC
March 2016

Potentials of incretin-based therapies in dementia and stroke in type 2 diabetes mellitus.

J Diabetes Investig 2016 Jan 3;7(1):5-16. Epub 2015 Oct 3.

University Medical Center Utrecht Brain Center Rudolf Magnus Department of Neurology Utrecht the Netherlands.

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http://dx.doi.org/10.1111/jdi.12420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718099PMC
January 2016

Hippocampal insulin resistance and cognitive dysfunction.

Nat Rev Neurosci 2015 Nov 14;16(11):660-71. Epub 2015 Oct 14.

Department of Pharmacology, Physiology and Neuroscience, University of South Carolina School of Medicine, 6439 Garners Ferry Road, VA Building 1, Room D40, Columbia, South Carolina 29208, USA.

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http://dx.doi.org/10.1038/nrn4019DOI Listing
November 2015

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images.

J Vis Exp 2015 Nov 20(105). Epub 2015 Nov 20.

Department of Radiology, University Medical Center Utrecht.

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http://dx.doi.org/10.3791/53125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692739PMC
November 2015