Geert Jan Biessels

Geert Jan Biessels

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Geert Jan Biessels

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Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration.

Authors:
Eric E Smith Geert Jan Biessels François De Guio Frank Erik de Leeuw Simon Duchesne Marco Düring Richard Frayne M Arfan Ikram Eric Jouvent Bradley J MacIntosh Michael J Thrippleton Meike W Vernooij Hieab Adams Walter H Backes Lucia Ballerini Sandra E Black Christopher Chen Rod Corriveau Charles DeCarli Steven M Greenberg M Edip Gurol Michael Ingrisch Dominic Job Bonnie Y K Lam Lenore J Launer Jennifer Linn Cheryl R McCreary Vincent C T Mok Leonardo Pantoni G Bruce Pike Joel Ramirez Yael D Reijmer Jose Rafael Romero Stefan Ropele Natalia S Rost Perminder S Sachdev Christopher J M Scott Sudha Seshadri Mukul Sharma Steven Sourbron Rebecca M E Steketee Richard H Swartz Robert van Oostenbrugge Matthias van Osch Sanneke van Rooden Anand Viswanathan David Werring Martin Dichgans Joanna M Wardlaw

Alzheimers Dement (Amst) 2019 Dec 26;11:191-204. Epub 2019 Feb 26.

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/j.dadm.2019.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396326PMC
December 2019

The Meta VCI Map consortium for meta-analyses on strategic lesion locations for vascular cognitive impairment using lesion-symptom mapping: Design and multicenter pilot study.

Authors:
Nick A Weaver Lei Zhao J Matthijs Biesbroek Hugo J Kuijf Hugo P Aben Hee-Joon Bae Miguel Á A Caballero Francesca M Chappell Christopher P L H Chen Martin Dichgans Marco Duering Marios K Georgakis Ruben S van der Giessen Bibek Gyanwali Olivia K L Hamilton Saima Hilal Elise M Vom Hofe Paul L M de Kort Peter J Koudstaal Bonnie Y K Lam Jae-Sung Lim Stephen D J Makin Vincent C T Mok Lin Shi Maria C Valdés Hernández Narayanaswamy Venketasubramanian Joanna M Wardlaw Frank A Wollenweber Adrian Wong Xu Xin Geert Jan Biessels

Alzheimers Dement (Amst) 2019 Dec 12;11:310-326. Epub 2019 Apr 12.

Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1016/j.dadm.2019.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465616PMC
December 2019

European Ultrahigh-Field Imaging Network for Neurodegenerative Diseases (EUFIND).

Authors:
Emrah Düzel Julio Acosta-Cabronero David Berron Geert Jan Biessels Isabella Björkman-Burtscher Michel Bottlaender Richard Bowtell Mark V Buchem Arturo Cardenas-Blanco Fawzi Boumezbeur Dennis Chan Stuart Clare Mauro Costagli Ludovic de Rochefort Ariane Fillmer Penny Gowland Oskar Hansson Jeroen Hendrikse Oliver Kraff Mark E Ladd Itamar Ronen Esben Petersen James B Rowe Hartwig Siebner Tony Stoecker Sina Straub Michela Tosetti Kamil Uludag Alexandre Vignaud Jaco Zwanenburg Oliver Speck

Alzheimers Dement (Amst) 2019 Dec 31;11:538-549. Epub 2019 Jul 31.

German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Magdeburg, Germany.

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http://dx.doi.org/10.1016/j.dadm.2019.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675944PMC
December 2019

Standardized Assessment of Automatic Segmentation of White Matter Hyperintensities and Results of the WMH Segmentation Challenge.

Authors:
Hugo J Kuijf Adria Casamitjana D Louis Collins Mahsa Dadar Achilleas Georgiou Mohsen Ghafoorian Dakai Jin April Khademi Jesse Knight Hongwei Li Xavier Llado J Matthijs Biesbroek Miguel Luna Qaiser Mahmood Richard McKinley Alireza Mehrtash Sebastien Ourselin Bo-Yong Park Hyunjin Park Sang Hyun Park Simon Pezold Elodie Puybareau Jeroen De Bresser Leticia Rittner Carole H Sudre Sergi Valverde Veronica Vilaplana Roland Wiest Yongchao Xu Ziyue Xu Guodong Zeng Jianguo Zhang Guoyan Zheng Rutger Heinen Christopher Chen Wiesje van der Flier Frederik Barkhof Max A Viergever Geert Jan Biessels Simon Andermatt Mariana Bento Matt Berseth Mikhail Belyaev M Jorge Cardoso

IEEE Trans Med Imaging 2019 Nov 19;38(11):2556-2568. Epub 2019 Mar 19.

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http://dx.doi.org/10.1109/TMI.2019.2905770DOI Listing
November 2019

Oxidative stress and endothelial dysfunction are associated with reduced cognition in type 2 diabetes.

Authors:
Onno N Groeneveld Esther van den Berg Odd Erik Johansen Sven Schnaidt Karin Hermansson Bernard Zinman Mark A Espeland Geert Jan Biessels

Diab Vasc Dis Res 2019 Nov 9;16(6):577-581. Epub 2019 May 9.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1177/1479164119848093DOI Listing
November 2019

Frequent Cognitive Impairment in Patients With Disorders Along the Heart-Brain Axis.

Authors:
Astrid M Hooghiemstra Anna E Leeuwis Anne Suzannne Bertens Geert Jan Biessels Michiel L Bots Hans-Peter Brunner-La Rocca Jacoba P Greving L Jaap Kappelle Robert J van Oostenbrugge Albert C van Rossum Wiesje M van der Flier

Stroke 2019 Nov 5:STROKEAHA119026031. Epub 2019 Nov 5.

From the Department of Neurology, Alzheimer Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, location VUmc, the Netherlands (A.M.H., A.E.L., W.M.v.d.F.).

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http://dx.doi.org/10.1161/STROKEAHA.119.026031DOI Listing
November 2019

High-Normal Adolescent Fasting Plasma Glucose Is Associated With Poorer Midlife Brain Health: Bogalusa Heart Study.

Authors:
Owen Carmichael Patrick Stuchlik Sreekrishna Pillai Geert-Jan Biessels Ram Dhullipudi Anna Madden-Rusnak Shane Martin Daniel S Hsia Vivian Fonseca Lydia Bazzano

J Clin Endocrinol Metab 2019 Oct;104(10):4492-4500

Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.

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http://dx.doi.org/10.1210/jc.2018-02750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736207PMC
October 2019

Effect of Linagliptin on Cognitive Performance in Patients With Type 2 Diabetes and Cardiorenal Comorbidities: The CARMELINA Randomized Trial.

Authors:
Geert Jan Biessels Chloë Verhagen Jolien Janssen Esther van den Berg Bernard Zinman Julio Rosenstock Jyothis T George Anna Passera Sven Schnaidt Odd Erik Johansen

Diabetes Care 2019 Oct 9;42(10):1930-1938. Epub 2019 Aug 9.

Biostatistics and Data Sciences, Boehringer Ingelheim, Biberach, Germany.

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http://dx.doi.org/10.2337/dc19-0783DOI Listing
October 2019

Assessment of the appropriate use criteria for amyloid PET in an unselected memory clinic cohort: The ABIDE project.

Authors:
Arno de Wilde Rik Ossenkoppele Wiesje Pelkmans Femke Bouwman Colin Groot Ingrid van Maurik Marissa Zwan Maqsood Yaqub Frederik Barkhof Adriaan A Lammertsma Geert Jan Biessels Philip Scheltens Bart N van Berckel Wiesje M van der Flier

Alzheimers Dement 2019 Oct 6. Epub 2019 Oct 6.

Department of Neurology, Amsterdam Neuroscience, Alzheimer Center, VU University, Amsterdam UMC, Amsterdam, the Netherlands; Department of Epidemiology and Biostatistics, Amsterdam Neuroscience, VU University of Amsterdam, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.jalz.2019.07.003DOI Listing
October 2019

Nonfocal Transient Neurological Attacks Are Associated With Cerebral Small Vessel Disease.

Authors:
Eline A Oudeman Jacoba P Greving Renske M Van den Berg-Vos Geert Jan Biessels Esther E Bron Robert van Oostenbrugge Jeroen de Bresser L Jaap Kappelle

Stroke 2019 Oct 22:STROKEAHA119025328. Epub 2019 Oct 22.

From the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, the Netherlands (E.A.O., G.J.B., L.J.K.).

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http://dx.doi.org/10.1161/STROKEAHA.119.025328DOI Listing
October 2019

Occurrence of Impaired Physical Performance in Memory Clinic Patients With Cerebral Small Vessel Disease.

Authors:
Jurre H Verwer Geert-Jan Biessels Rutger Heinen Lieza G Exalto Marielle H Emmelot-Vonk Huiberdina L Koek

Alzheimer Dis Assoc Disord 2018 Jul-Sep;32(3):214-219

Department of Geriatrics, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1097/WAD.0000000000000233DOI Listing
September 2019

Diabetic Retinopathy and Dementia in Type 1 Diabetes.

Authors:
Liora G Rodill Lieza G Exalto Paola Gilsanz Geert Jan Biessels Charles P Quesenberry Rachel A Whitmer

Alzheimer Dis Assoc Disord 2018 Apr-Jun;32(2):125-130

Kaiser Permanente Division of Research.

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http://dx.doi.org/10.1097/WAD.0000000000000230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963957PMC
September 2019

Physical Performance in Memory Clinic Patients: The Potential Role of the White Matter Network.

Authors:
Jurre H Verwer Yael D Reijmer Huiberdina L Koek Geert Jan Biessels

J Am Geriatr Soc 2019 Sep 28;67(9):1880-1887. Epub 2019 May 28.

Department of Neurology, Neurosurgery, and Neuropsychology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jgs.15987
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http://dx.doi.org/10.1111/jgs.15987DOI Listing
September 2019

Reply to: Comment on Physical Performance in Memory Clinic Patients: The Potential Role of the White Matter Network.

Authors:
Jurre H Verwer Yael D Reijmer Huiberdina L Koek Geert Jan Biessels

J Am Geriatr Soc 2019 Sep 13. Epub 2019 Sep 13.

Department of Neurology, Neurosurgery, and Neuropsychology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1111/jgs.16160DOI Listing
September 2019

Cortical microinfarcts in memory clinic patients are associated with reduced cerebral perfusion.

Authors:
Doeschka A Ferro Henri Jjm Mutsaerts Saima Hilal Hugo J Kuijf Esben T Petersen Jan Petr Susanne J van Veluw Narayanaswamy Venketasubramanian Tan Boon Yeow Geert Jan Biessels Christopher Chen

J Cereb Blood Flow Metab 2019 Sep 26:271678X19877403. Epub 2019 Sep 26.

Memory Aging and Cognition Centre, Department of Pharmacology, National University of Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1177/0271678X19877403DOI Listing
September 2019

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping.

Authors:
J Matthijs Biesbroek Hugo J Kuijf Nick A Weaver Lei Zhao Marco Duering Geert Jan Biessels

J Vis Exp 2019 Sep 25(151). Epub 2019 Sep 25.

Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University.

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http://dx.doi.org/10.3791/59653DOI Listing
September 2019

Automated Multi-Atlas Segmentation of Hippocampal and Extrahippocampal Subregions in Alzheimer's Disease at 3T and 7T: What Atlas Composition Works Best?

Authors:
Long Xie Russell T Shinohara Ranjit Ittyerah Hugo J Kuijf John B Pluta Kim Blom Minke Kooistra Yael D Reijmer Huiberdina L Koek Jaco J M Zwanenburg Hongzhi Wang Peter R Luijten Mirjam I Geerlings Sandhitsu R Das Geert Jan Biessels David A Wolk Paul A Yushkevich Laura E M Wisse

J Alzheimers Dis 2018 ;63(1):217-225

Department of Radiology, Penn Image Computing and Science Laboratory (PICSL), University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.3233/JAD-170932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468320PMC
August 2019

Hippocampal sulcal cavities: prevalence, risk factors and association with cognitive performance. The SMART-Medea study and PREDICT-MR study.

Authors:
Kim Blom Huiberdina L Koek Yolanda van der Graaf Maarten H T Zwartbol Laura E M Wisse Jeroen Hendrikse Geert Jan Biessels Mirjam I Geerlings

Brain Imaging Behav 2019 Aug;13(4):1093-1102

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6.131, P.O. Box 85500, 3508, GA, Utrecht, the Netherlands.

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http://dx.doi.org/10.1007/s11682-018-9916-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647498PMC
August 2019

Nonfocal transient neurological attacks are related to cognitive impairment in patients with heart failure.

Authors:
Eline A Oudeman Jacoba P Greving Astrid M Hooghiemstra Hans-Peter Brunner-La Rocca Geert Jan Biessels L Jaap Kappelle

J Neurol 2019 Aug 21;266(8):2035-2042. Epub 2019 May 21.

Department of Neurology and Neurosurgery, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s00415-019-09376-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647193PMC
August 2019

Cerebral Perfusion and the Occurrence of Nonfocal Transient Neurological Attacks.

Authors:
Eline A Oudeman Esther E Bron Renske M Van den Berg-Vos Jacoba P Greving Geert Jan Biessels Catharina J M Klijn L Jaap Kappelle

Cerebrovasc Dis 2019 16;47(5-6):303-308. Epub 2019 Aug 16.

Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1159/000502334DOI Listing
August 2019

Cerebral amyloid burden is associated with white matter hyperintensity location in specific posterior white matter regions.

Authors:
Nick A Weaver Thomas Doeven Frederik Barkhof J Matthijs Biesbroek Onno N Groeneveld Hugo J Kuijf Niels D Prins Philip Scheltens Charlotte E Teunissen Wiesje M van der Flier Geert Jan Biessels

Neurobiol Aging 2019 Aug 9. Epub 2019 Aug 9.

Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, the Netherlands.

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.08.001DOI Listing
August 2019

Impact of white matter hyperintensity location on depressive symptoms in memory-clinic patients: a lesion–symptom mapping study

Authors:
Anna E. Leeuwis Nick A. Weaver J. Matthijs Biesbroek Lieza G. Exalto Hugo J. Kuijf Astrid M. Hooghiemstra Niels D. Prins Philip Scheltens Frederik Barkhof Wiesje M. van der Flier Geert Jan Biessels

J Psychiatry Neurosci 2019 07;44(4):E1-E10

From the Alzheimer Centre Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands (Leeuwis, Hooghiemstra, Prins, Scheltens, van der Flier); the Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht, the Netherlands (Weaver, Biesbroek, Exalto, Biessels); the Image Sciences Institute, University Medical Centre Utrecht, Utrecht, the Netherlands (Kuijf); the Department of Medical Humanities, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (Hooghiemstra); the Institutes of Neurology and Healthcare Engineering, UCL, London, United Kingdom (Barkhof); the Department of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (Barkhof); and the Department of Epidemiology & Biostatistics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (Flier).

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http://dx.doi.org/10.1503/jpn.180136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606429PMC
July 2019

Subjective cognitive decline, brain imaging biomarkers, and cognitive functioning in patients with a history of vascular disease: the SMART-Medea study.

Authors:
Kim Blom Huiberdina L Koek Maarten H T Zwartbol Yolanda van der Graaf Lara Kesseler Geert Jan Biessels Mirjam I Geerlings

Neurobiol Aging 2019 Jul 24;84:33-40. Epub 2019 Jul 24.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht and Utrecht University, Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.07.011DOI Listing
July 2019

White Matter Hyperintensities and Cognition in Mild Cognitive Impairment and Alzheimer's Disease: A Domain-Specific Meta-Analysis.

Authors:
Esther van den Berg Mirjam I Geerlings Geert Jan Biessels Paul J Nederkoorn Raoul P Kloppenborg

J Alzheimers Dis 2018 ;63(2):515-527

Department of Neurology, Franciscus, Rotterdam, The Netherlands.

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http://dx.doi.org/10.3233/JAD-170573DOI Listing
June 2019

Cortical Microinfarcts and White Matter Connectivity in Memory Clinic Patients.

Authors:
Doeschka Ferro Rutger Heinen Bruno de Brito Robalo Hugo Kuijf Geert Jan Biessels Yael Reijmer

Front Neurol 2019 5;10:571. Epub 2019 Jun 5.

Brain Center, University Medical Center Utrecht, Department of Neurology, University Medical Center Utrecht, University Utrecht, Utrecht, Netherlands.

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http://dx.doi.org/10.3389/fneur.2019.00571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560058PMC
June 2019

Treatment of Diabetes in Older Adults: An Endocrine Society* Clinical Practice Guideline.

Authors:
Derek LeRoith Geert Jan Biessels Susan S Braithwaite Felipe F Casanueva Boris Draznin Jeffrey B Halter Irl B Hirsch Marie E McDonnell Mark E Molitch M Hassan Murad Alan J Sinclair

J Clin Endocrinol Metab 2019 May;104(5):1520-1574

King's College, London, United Kingdom.

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http://dx.doi.org/10.1210/jc.2019-00198DOI Listing
May 2019

Clinical relevance of acute cerebral microinfarcts in vascular cognitive impairment.

Authors:
Doeschka A Ferro Hilde van den Brink Lieza G Exalto Jooske M F Boomsma Frederik Barkhof Niels D Prins Wiesje M van der Flier Geert Jan Biessels

Neurology 2019 Apr 8;92(14):e1558-e1566. Epub 2019 Mar 8.

From the Department of Neurology (D.A.F., H.v.d.B., L.G.E., J.M.F.B., G.J.B.), Brain Center UMC Utrecht, University Medical Center Utrecht, Utrecht University; Department of Neurology (J.M.F.B.), Onze Lieve Vrouwe Gasthuis (OLVG) West; Department of Radiology & Nuclear Medicine (F.B.) Department of Neurology and Alzheimer Center Amsterdam (N.D.P., W.M.v.d.F.), Department of Epidemiology & Biostatistics (W.M.v.d.F.), Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, the Netherlands; and Institutes of Neurology and Healthcare Engineering (F.B.), University College London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000007250DOI Listing
April 2019

White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities.

Authors:
Jessica Alber Suvarna Alladi Hee-Joon Bae David A Barton Laurel A Beckett Joanne M Bell Sara E Berman Geert Jan Biessels Sandra E Black Isabelle Bos Gene L Bowman Emanuele Brai Adam M Brickman Brandy L Callahan Roderick A Corriveau Silvia Fossati Rebecca F Gottesman Deborah R Gustafson Vladimir Hachinski Kathleen M Hayden Alex M Helman Timothy M Hughes Jeremy D Isaacs Angela L Jefferson Sterling C Johnson Alifiya Kapasi Silke Kern Jay C Kwon Juraj Kukolja Athene Lee Samuel N Lockhart Anne Murray Katie E Osborn Melinda C Power Brittani R Price Hanneke F M Rhodius-Meester Jacqueline A Rondeau Allyson C Rosen Douglas L Rosene Julie A Schneider Henrieta Scholtzova C Elizabeth Shaaban Narlon C B S Silva Heather M Snyder Walter Swardfager Aron M Troen Susanne J van Veluw Prashanthi Vemuri Anders Wallin Cheryl Wellington Donna M Wilcock Sharon Xiangwen Xie Atticus H Hainsworth

Alzheimers Dement (N Y) 2019 9;5:107-117. Epub 2019 Apr 9.

Molecular & Clinical Sciences Research Institute, St George's University of London and Department of Neurology, St George's University Hospitals NHS Foundation Trust, London, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S23528737193000
Publisher Site
http://dx.doi.org/10.1016/j.trci.2019.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461571PMC
April 2019

People with type 2 diabetes and screen-detected cognitive impairment use acute health care services more often: observations from the COG-ID study.

Authors:
Jolien Janssen Paula S Koekkoek Geert Jan Biessels L Jaap Kappelle Guy E H M Rutten

Diabetol Metab Syndr 2019 22;11:21. Epub 2019 Feb 22.

1Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1186/s13098-019-0416-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387554PMC
February 2019

The cumulative effect of small vessel disease lesions is reflected in structural brain networks of memory clinic patients.

Authors:
Rutger Heinen Naomi Vlegels Jeroen de Bresser Alexander Leemans Geert Jan Biessels Yael D Reijmer

Neuroimage Clin 2018 19;19:963-969. Epub 2018 Jun 19.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S22131582183020
Publisher Site
http://dx.doi.org/10.1016/j.nicl.2018.06.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039838PMC
January 2019

Vascular dysfunction-The disregarded partner of Alzheimer's disease.

Authors:
Melanie D Sweeney Axel Montagne Abhay P Sagare Daniel A Nation Lon S Schneider Helena C Chui Michael G Harrington Judy Pa Meng Law Danny J J Wang Russell E Jacobs Fergus N Doubal Joel Ramirez Sandra E Black Maiken Nedergaard Helene Benveniste Martin Dichgans Costantino Iadecola Seth Love Philip M Bath Hugh S Markus Rustam A Salman Stuart M Allan Terence J Quinn Rajesh N Kalaria David J Werring Roxana O Carare Rhian M Touyz Steve C R Williams Michael A Moskowitz Zvonimir S Katusic Sarah E Lutz Orly Lazarov Richard D Minshall Jalees Rehman Thomas P Davis Cheryl L Wellington Hector M González Chun Yuan Samuel N Lockhart Timothy M Hughes Christopher L H Chen Perminder Sachdev John T O'Brien Ingmar Skoog Leonardo Pantoni Deborah R Gustafson Geert Jan Biessels Anders Wallin Eric E Smith Vincent Mok Adrian Wong Peter Passmore Frederick Barkof Majon Muller Monique M B Breteler Gustavo C Román Edith Hamel Sudha Seshadri Rebecca F Gottesman Mark A van Buchem Zoe Arvanitakis Julie A Schneider Lester R Drewes Vladimir Hachinski Caleb E Finch Arthur W Toga Joanna M Wardlaw Berislav V Zlokovic

Alzheimers Dement 2019 01;15(1):158-167

Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Alzheimer's Disease Research Center, Keck School of Medicine at the University of Southern California, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.07.222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338083PMC
January 2019

The Clinical Phenotype of Vascular Cognitive Impairment in Patients with Type 2 Diabetes Mellitus.

Authors:
Onno N Groeneveld Costanza Moneti Rutger Heinen Jeroen de Bresser Hugo J Kuijf Lieza G Exalto Jooske M F Boomsma L Jaap Kappelle Frederik Barkhof Niels D Prins Philip Scheltens Wiesje M van der Flier Geert Jan Biessels

J Alzheimers Dis 2019 ;68(1):311-322

Department of Neurology, Brain Center Rudolph Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.3233/JAD-180914DOI Listing
January 2019

Depressive symptoms and quality of life after screening for cognitive impairment in patients with type 2 diabetes: observations from the Cog-ID cohort study.

Authors:
Jolien Janssen Paula S Koekkoek Geert-Jan Biessels Jaap L Kappelle Guy E H M Rutten

BMJ Open 2019 01 17;9(1):e024696. Epub 2019 Jan 17.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1136/bmjopen-2018-024696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340460PMC
January 2019

HbA, Insulin Resistance, and β-Cell Function in Relation to Cognitive Function in Type 2 Diabetes: The CAROLINA Cognition Substudy.

Authors:
Jolien Janssen Esther van den Berg Bernard Zinman Mark A Espeland Stefan L C Geijselaers Michaela Mattheus Odd Erik Johansen Geert Jan Biessels

Diabetes Care 2019 01;42(1):e1-e3

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.2337/DC18-0914DOI Listing
January 2019

How Do Different Forms of Vascular Brain Injury Relate to Cognition in a Memory Clinic Population: The TRACE-VCI Study.

Authors:
Jooske M F Boomsma Lieza G Exalto Frederik Barkhof Esther van den Berg Jeroen de Bresser Rutger Heinen Anna E Leeuwis Niels D Prins Philip Scheltens Henry C Weinstein Wiesje M van der Flier Geert Jan Biessels

J Alzheimers Dis 2019 ;68(3):1273-1286

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http://dx.doi.org/10.3233/JAD-180696DOI Listing
January 2019

Higher Pulsatility in Cerebral Perforating Arteries in Patients With Small Vessel Disease Related Stroke, a 7T MRI Study.

Authors:
Lennart J Geurts Jaco J M Zwanenburg Catharina J M Klijn Peter R Luijten Geert Jan Biessels

Stroke 2018 Dec 11:STROKEAHA118022516. Epub 2018 Dec 11.

Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, The Netherlands (C.J.M.K., G.J.B.).

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http://dx.doi.org/10.1161/STROKEAHA.118.022516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314503PMC
December 2018

Parietal Involvement in Constructional Apraxia as Measured Using the Pentagon Copying Task.

Authors:
Stefan Van der Stigchel Jeroen de Bresser Rutger Heinen Huiberdina L Koek Yael D Reijmer Geert Jan Biessels Esther van den Berg

Dement Geriatr Cogn Disord 2018 24;46(1-2):50-59. Epub 2018 Aug 24.

Department of Neurology, Erasmus MC University Medical Centre, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1159/000491634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187841PMC
November 2018

HbA, Insulin Resistance, and β-Cell Function in Relation to Cognitive Function in Type 2 Diabetes: The CAROLINA Cognition Substudy.

Authors:
Jolien Janssen Esther van den Berg Bernard Zinman Mark A Espeland Stefan L C Geijselaers Michaela Mattheus Odd Erik Johansen Geert Jan Biessels

Diabetes Care 2018 Nov 19. Epub 2018 Nov 19.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.2337/dc18-0914DOI Listing
November 2018

Cognitive decline and dementia in diabetes mellitus: mechanisms and clinical implications.

Authors:
Geert Jan Biessels Florin Despa

Nat Rev Endocrinol 2018 10;14(10):591-604

Department of Pharmacology and Nutritional Sciences and Department of Neurology, University of Kentucky, Lexington, KY, USA.

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http://dx.doi.org/10.1038/s41574-018-0048-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397437PMC
October 2018

Microstructure of Strategic White Matter Tracts and Cognition in Memory Clinic Patients with Vascular Brain Injury.

Authors:
J Matthijs Biesbroek Alexander Leemans Hanna den Bakker Marco Duering Benno Gesierich Huiberdina L Koek Esther van den Berg Albert Postma Geert Jan Biessels

Dement Geriatr Cogn Disord 2017 19;44(5-6):268-282. Epub 2018 Jan 19.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1159/000485376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972515PMC
September 2018

Association of Amyloid Positron Emission Tomography With Changes in Diagnosis and Patient Treatment in an Unselected Memory Clinic Cohort: The ABIDE Project.

Authors:
Arno de Wilde Wiesje M van der Flier Wiesje Pelkmans Femke Bouwman Jurre Verwer Colin Groot Marieke M van Buchem Marissa Zwan Rik Ossenkoppele Maqsood Yaqub Marleen Kunneman Ellen M A Smets Frederik Barkhof Adriaan A Lammertsma Andrew Stephens Erik van Lier Geert Jan Biessels Bart N van Berckel Philip Scheltens

JAMA Neurol 2018 09;75(9):1062-1070

Department of Neurology & Alzheimer Center, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1001/jamaneurol.2018.1346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143118PMC
September 2018

Carotid circumferential wall stress is not associated with cognitive performance among individuals in late middle age: The Maastricht Study.

Authors:
Stefan Lc Geijselaers Simone Js Sep Miranda T Schram Martin Pj van Boxtel Thomas T van Sloten Jos Op Het Roodt Ronald Ma Henry Koen D Reesink Nicolaas C Schaper Pieter C Dagnelie Carla Jh van der Kallen Geert Jan Biessels Coen DA Stehouwer

Atherosclerosis 2018 09 4;276:15-22. Epub 2018 Jul 4.

Department of Internal Medicine, Maastricht University Medical Centre +, Maastricht, the Netherlands; CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, the Netherlands.

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.07.003DOI Listing
September 2018

Microstructural White Matter Abnormalities and Cognitive Impairment After Aneurysmal Subarachnoid Hemorrhage.

Authors:
Yael D Reijmer Marc S van den Heerik Rutger Heinen Alexander Leemans Jeroen Hendrikse Jill B de Vis Lisa A van der Kleij Carlo Lucci Mariska E Hendriks Martine J E van Zandvoort Irene M C Huenges Wajer J M Anne Visser-Meily Gabriel J E Rinkel Geert Jan Biessels Mervyn D I Vergouwen

Stroke 2018 09;49(9):2040-2045

From the Department of Neurology and Neurosurgery (Y.D.R., M.S.v.d.H., R.H., M.J.E.v.Z., I.M.C.H.W., G.J.E.R., G.J.B., M.D.I.V.).

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September 2018

Applicability of diagnostic constructs for cognitive impairment in patients with type 2 diabetes mellitus.

Authors:
Onno N Groeneveld Esther van den Berg Guy E H M Rutten Paula S Koekkoek L Jaap Kappelle Geert Jan Biessels

Diabetes Res Clin Pract 2018 Aug 24;142:92-99. Epub 2018 May 24.

University Medical Center Utrecht, Brain Center Rudolf Magnus, Department of Neurology, PO Box 85500, 3508 GA Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.diabres.2018.05.025DOI Listing
August 2018

Cortical Microinfarcts on 3T Magnetic Resonance Imaging in Cerebral Amyloid Angiopathy.

Authors:
Hilde van den Brink Angela Zwiers Aaron R Switzer Anna Charlton Cheryl R McCreary Bradley G Goodyear Richard Frayne Geert Jan Biessels Eric E Smith

Stroke 2018 08;49(8):1899-1905

Department of Clinical Neurosciences (A.Z., A.R.S., A.C., B.G.G., C.R.M., E.E.S., R.F.).

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August 2018

The Missing Link in the Pathophysiology of Vascular Cognitive Impairment: Design of the Heart-Brain Study.

Authors:
Astrid M Hooghiemstra Anne Suzanne Bertens Anna E Leeuwis Esther E Bron Michiel L Bots Hans-Peter Brunner-La Rocca Anton J M de Craen Rob J van der Geest Jacoba P Greving L Jaap Kappelle Wiro J Niessen Robert J van Oostenbrugge Matthias J P van Osch Albert de Roos Albert C van Rossum Geert Jan Biessels Mark A van Buchem Mat J A P Daemen Wiesje M van der Flier

Cerebrovasc Dis Extra 2017 10;7(3):140-152. Epub 2017 Oct 10.

Alzheimer Center & Department of Neurology, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1159/000480738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730112PMC
July 2018

Cortical Cerebral Microinfarcts on 3 Tesla MRI in Patients with Vascular Cognitive Impairment.

Authors:
Doeschka A Ferro Susanne J van Veluw Huiberdina L Koek Lieza G Exalto Geert Jan Biessels

J Alzheimers Dis 2017 ;60(4):1443-1450

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, The Netherlands.

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http://dx.doi.org/10.3233/JAD-170481DOI Listing
July 2018

Association of Cerebrospinal Fluid (CSF) Insulin with Cognitive Performance and CSF Biomarkers of Alzheimer's Disease.

Authors:
Stefan L C Geijselaers Pauline Aalten Inez H G B Ramakers Peter Paul De Deyn Annemieke C Heijboer Huiberdina L Koek Marcel G M OldeRikkert Janne M Papma Fransje E Reesink Lieke L Smits Coen D A Stehouwer Charlotte E Teunissen Frans R J Verhey Wiesje M van der Flier Geert Jan Biessels

J Alzheimers Dis 2018 ;61(1):309-320

Department of Internal Medicine and Cardiovascular Research Institute, Maastricht University Medical Centre +, Maastricht, the Netherlands.

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http://dx.doi.org/10.3233/JAD-170522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734123PMC
July 2018

Evaluation of a deep learning approach for the segmentation of brain tissues and white matter hyperintensities of presumed vascular origin in MRI.

Authors:
Pim Moeskops Jeroen de Bresser Hugo J Kuijf Adriënne M Mendrik Geert Jan Biessels Josien P W Pluim Ivana Išgum

Neuroimage Clin 2018 12;17:251-262. Epub 2017 Oct 12.

Image Sciences Institute, University Medical Center Utrecht and Utrecht University, The Netherlands.

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http://dx.doi.org/10.1016/j.nicl.2017.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683197PMC
June 2018

Free water determines diffusion alterations and clinical status in cerebral small vessel disease.

Authors:
Marco Duering Sofia Finsterwalder Ebru Baykara Anil Man Tuladhar Benno Gesierich Marek J Konieczny Rainer Malik Nicolai Franzmeier Michael Ewers Eric Jouvent Geert Jan Biessels Reinhold Schmidt Frank-Erik de Leeuw Ofer Pasternak Martin Dichgans

Alzheimers Dement 2018 06 16;14(6):764-774. Epub 2018 Feb 16.

Institute for Stroke and Dementia Research, University Hospital, LMU Munich, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.

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http://dx.doi.org/10.1016/j.jalz.2017.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994358PMC
June 2018

Vascular reactivity in small cerebral perforating arteries with 7 T phase contrast MRI - A proof of concept study.

Authors:
Lennart J Geurts Alex A Bhogal Jeroen C W Siero Peter R Luijten Geert Jan Biessels Jaco J M Zwanenburg

Neuroimage 2018 05 14;172:470-477. Epub 2018 Feb 14.

Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.neuroimage.2018.01.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915583PMC
May 2018

A Role for New Brain Magnetic Resonance Imaging Modalities in Daily Clinical Practice: Protocol of the Prediction of Cognitive Recovery After Stroke (PROCRAS) Study.

Authors:
Hugo P Aben Yael D Reijmer Johanna Ma Visser-Meily Jacoba M Spikman Jeroen de Bresser Geert Jan Biessels Paul Lm de Kort

JMIR Res Protoc 2018 May 28;7(5):e127. Epub 2018 May 28.

Elisabeth Tweesteden Hospital, Department of Neurology, Tilburg, Netherlands.

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http://www.researchprotocols.org/2018/5/e127/
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http://dx.doi.org/10.2196/resprot.9431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997934PMC
May 2018

Better and faster velocity pulsatility assessment in cerebral white matter perforating arteries with 7T quantitative flow MRI through improved slice profile, acquisition scheme, and postprocessing.

Authors:
Lennart Geurts Geert Jan Biessels Peter Luijten Jaco Zwanenburg

Magn Reson Med 2018 03 11;79(3):1473-1482. Epub 2017 Jul 11.

UMC Utrecht, Department of Radiology, Utrecht, the Netherlands.

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http://dx.doi.org/10.1002/mrm.26821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811780PMC
March 2018

Patterns of progressive atrophy vary with age in Alzheimer's disease patients.

Authors:
Cassidy M Fiford Gerard R Ridgway David M Cash Marc Modat Jennifer Nicholas Emily N Manning Ian B Malone Geert Jan Biessels Sebastien Ourselin Owen T Carmichael M Jorge Cardoso Josephine Barnes

Neurobiol Aging 2018 03 14;63:22-32. Epub 2017 Nov 14.

Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805840PMC
March 2018

Symptomatic Treatment of Vascular Cognitive Impairment (STREAM-VCI): Protocol for a Cross-Over Trial.

Authors:
Jolien Fleur Leijenaar Geert Jan Groeneveld Wiesje Maria van der Flier Philip Scheltens Erica Surya Klaassen Henry Chanoch Weinstein Geert Jan Biessels Frederik Barkhof Niels Daniël Prins

JMIR Res Protoc 2018 Mar 20;7(3):e80. Epub 2018 Mar 20.

Alzheimer Center & Department of Neurology, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, Netherlands.

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http://dx.doi.org/10.2196/resprot.9192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883073PMC
March 2018

Rationale and design of the CAROLINA® - cognition substudy: a randomised controlled trial on cognitive outcomes of linagliptin versus glimepiride in patients with type 2 diabetes mellitus.

Authors:
Geert Jan Biessels Jolien Janssen Esther van den Berg Bernard Zinman Mark A Espeland Michaela Mattheus Odd Erik Johansen

BMC Neurol 2018 Jan 15;18(1). Epub 2018 Jan 15.

Clinical development, Therapeutic Area Metabolism, Boehringer Ingelheim, Asker, Norway.

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http://dx.doi.org/10.1186/s12883-018-1014-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769408PMC
January 2018

White matter hyperintensity shape and location feature analysis on brain MRI; proof of principle study in patients with diabetes.

Authors:
Jeroen de Bresser Hugo J Kuijf Karlijn Zaanen Max A Viergever Jeroen Hendrikse Geert Jan Biessels

Sci Rep 2018 01 30;8(1):1893. Epub 2018 Jan 30.

Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/s41598-018-20084-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789823PMC
January 2018

How to choose the most appropriate cognitive test to evaluate cognitive complaints in primary care.

Authors:
Jolien Janssen Paula S Koekkoek Eric P Moll van Charante L Jaap Kappelle Geert Jan Biessels Guy E H M Rutten

BMC Fam Pract 2017 Dec 16;18(1):101. Epub 2017 Dec 16.

Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1186/s12875-017-0675-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732477PMC
December 2017

The Role of Hyperglycemia, Insulin Resistance, and Blood Pressure in Diabetes-Associated Differences in Cognitive Performance-The Maastricht Study.

Authors:
Stefan L C Geijselaers Simone J S Sep Danny Claessens Miranda T Schram Martin P J van Boxtel Ronald M A Henry Frans R J Verhey Abraham A Kroon Pieter C Dagnelie Casper G Schalkwijk Carla J H van der Kallen Geert Jan Biessels Coen D A Stehouwer

Diabetes Care 2017 11 25;40(11):1537-1547. Epub 2017 Aug 25.

Department of Internal Medicine, Maastricht University Medical Centre+, Maastricht, the Netherlands

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http://care.diabetesjournals.org/lookup/doi/10.2337/dc17-033
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http://dx.doi.org/10.2337/dc17-0330DOI Listing
November 2017

Detection, risk factors, and functional consequences of cerebral microinfarcts.

Authors:
Susanne J van Veluw Andy Y Shih Eric E Smith Christopher Chen Julie A Schneider Joanna M Wardlaw Steven M Greenberg Geert Jan Biessels

Lancet Neurol 2017 09 14;16(9):730-740. Epub 2017 Jul 14.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(17)30196-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861500PMC
September 2017

Abnormalities of Cerebral Deep Medullary Veins on 7 Tesla MRI in Amnestic Mild Cognitive Impairment and Early Alzheimer's Disease: A Pilot Study.

Authors:
Willem H Bouvy Hugo J Kuijf Jaco J M Zwanenburg Huiberdina L Koek L Jaap Kappelle Peter R Luijten M Kamran Ikram Geert Jan Biessels

J Alzheimers Dis 2017 ;57(3):705-710

Brain Center Rudolf Magnus, Department of Neurology, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.3233/JAD-160952DOI Listing
August 2017

Brain microvascular injury and white matter disease provoked by diabetes-associated hyperamylinemia.

Authors:
Han Ly Nirmal Verma Fengen Wu Miao Liu Kathryn E Saatman Peter T Nelson John T Slevin Larry B Goldstein Geert Jan Biessels Florin Despa

Ann Neurol 2017 Aug 29;82(2):208-222. Epub 2017 Jul 29.

Department of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, KY.

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http://dx.doi.org/10.1002/ana.24992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568970PMC
August 2017

Robustness of Automated Methods for Brain Volume Measurements across Different MRI Field Strengths.

Authors:
Rutger Heinen Willem H Bouvy Adrienne M Mendrik Max A Viergever Geert Jan Biessels Jeroen de Bresser

PLoS One 2016 31;11(10):e0165719. Epub 2016 Oct 31.

Department of Radiology, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0165719PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087903PMC
June 2017

Impact of Strategically Located White Matter Hyperintensities on Cognition in Memory Clinic Patients with Small Vessel Disease.

Authors:
J Matthijs Biesbroek Nick A Weaver Saima Hilal Hugo J Kuijf Mohammad Kamran Ikram Xin Xu Boon Yeow Tan Narayanaswamy Venketasubramanian Albert Postma Geert Jan Biessels Christopher P L H Chen

PLoS One 2016 8;11(11):e0166261. Epub 2016 Nov 8.

Memory Aging & Cognition Centre, National University Health System, Singapore, Singapore.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0166261PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100905PMC
June 2017

Insulin resistance and cognitive performance in type 2 diabetes - The Maastricht study.

Authors:
Stefan L C Geijselaers Simone J S Sep Miranda T Schram Martin P J van Boxtel Ronald M A Henry Frans R J Verhey Abraham A Kroon Nicolaas C Schaper Pieter C Dagnelie Carla J H van der Kallen Coen D A Stehouwer Geert Jan Biessels

J Diabetes Complications 2017 May 12;31(5):824-830. Epub 2017 Feb 12.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1016/j.jdiacomp.2017.01.020DOI Listing
May 2017

Impaired Emotion Recognition after Left Hemispheric Stroke: A Case Report and Brief Review of the Literature.

Authors:
Hugo P Aben Yael D Reijmer Johanna M A Visser-Meily Jacoba M Spikman Geert Jan Biessels Paul L M de Kort Procras Study Group

Case Rep Neurol Med 2017 7;2017:1045039. Epub 2017 May 7.

Department of Neurology, Elisabeth Tweesteden Hospital, Tilburg, Netherlands.

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http://dx.doi.org/10.1155/2017/1045039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438834PMC
May 2017

Rule induction performance in amnestic mild cognitive impairment and Alzheimer's dementia: examining the role of simple and biconditional rule learning processes.

Authors:
Joukje M Oosterman Sophie M Heringa Roy P C Kessels Geert Jan Biessels Huiberdina L Koek Joseph H R Maes Esther van den Berg

J Clin Exp Neuropsychol 2017 Apr 12;39(3):231-241. Epub 2016 Sep 12.

d Department of Neurology, Brain Center Rudolf Magnus , University Medical Center , Utrecht , the Netherlands.

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http://dx.doi.org/10.1080/13803395.2016.1218444DOI Listing
April 2017

Association Between Subclinical Cardiac Biomarkers and Clinically Manifest Cardiac Diseases With Cortical Cerebral Microinfarcts.

Authors:
Saima Hilal Yuek Ling Chai Susanne van Veluw Muhammad Amin Shaik Mohammad Kamran Ikram Narayanaswamy Venketasubramanian Arthur Mark Richards Geert Jan Biessels Christopher Chen

JAMA Neurol 2017 04;74(4):403-410

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore2Memory Aging and Cognition Center, National University Health System, Singapore.

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http://archneur.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaneurol.2016.5335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470359PMC
April 2017

Lesion location and cognitive impact of cerebral small vessel disease.

Authors:
J Matthijs Biesbroek Nick A Weaver Geert Jan Biessels

Clin Sci (Lond) 2017 Apr;131(8):715-728

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands.

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http://dx.doi.org/10.1042/CS20160452DOI Listing
April 2017

Vascular Cognitive Impairment in a Memory Clinic Population: Rationale and Design of the "Utrecht-Amsterdam Clinical Features and Prognosis in Vascular Cognitive Impairment" (TRACE-VCI) Study.

Authors:
Jooske Marije Funke Boomsma Lieza Geertje Exalto Frederik Barkhof Esther van den Berg Jeroen de Bresser Rutger Heinen Huiberdina Lena Koek Niels Daniël Prins Philip Scheltens Henry Chanoch Weinstein Wiesje Maria van der Flier Geert Jan Biessels

JMIR Res Protoc 2017 Apr 19;6(4):e60. Epub 2017 Apr 19.

Department of Neurology, Neurosurgery and Neuropsychology, Brain Centre Rudolf Magnus Institute, University Medical Centre Utrecht, Utrecht, Netherlands.

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http://dx.doi.org/10.2196/resprot.6864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415656PMC
April 2017

Reduced vascular amyloid burden at microhemorrhage sites in cerebral amyloid angiopathy.

Authors:
Susanne J van Veluw Hugo J Kuijf Andreas Charidimou Anand Viswanathan Geert Jan Biessels Annemieke J M Rozemuller Matthew P Frosch Steven M Greenberg

Acta Neuropathol 2017 03 22;133(3):409-415. Epub 2016 Oct 22.

Department of Neurology, J. Philip Kistler Stroke Research Center, Harvard Medical School, Massachusetts General Hospital, 175 Cambridge Street, Suite 300, Boston, MA, 02114, USA.

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http://link.springer.com/10.1007/s00401-016-1635-0
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http://dx.doi.org/10.1007/s00401-016-1635-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325834PMC
March 2017

White matter hyperintensities are associated with disproportionate progressive hippocampal atrophy.

Authors:
Cassidy M Fiford Emily N Manning Jonathan W Bartlett David M Cash Ian B Malone Gerard R Ridgway Manja Lehmann Kelvin K Leung Carole H Sudre Sebastien Ourselin Geert Jan Biessels Owen T Carmichael Nick C Fox M Jorge Cardoso Josephine Barnes

Hippocampus 2017 03 9;27(3):249-262. Epub 2017 Jan 9.

Department of Neurodegenerative Disease, Dementia Research Centre, UCL Institute of Neurology, London, United Kingdom.

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http://dx.doi.org/10.1002/hipo.22690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324634PMC
March 2017

Brain volume and cognitive function in patients with revascularized coronary artery disease.

Authors:
Thomas H Ottens Jeroen Hendrikse Hendrik M Nathoe Geert Jan Biessels Diederik van Dijk

Int J Cardiol 2017 Mar 21;230:80-84. Epub 2016 Dec 21.

Department of Intensive Care, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.ijcard.2016.12.079DOI Listing
March 2017

Chronic hyperglycemia is related to poor functional outcome after acute ischemic stroke.

Authors:
Merel Ja Luitse Birgitta K Velthuis L Jaap Kappelle Yolanda van der Graaf Geert Jan Biessels

Int J Stroke 2017 02 26;12(2):180-186. Epub 2016 Oct 26.

1 Department of Neurology and Neurosurgery, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1177/1747493016676619DOI Listing
February 2017

Prevention of Stroke in Patients With Silent Cerebrovascular Disease: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association.

Authors:
Eric E Smith Gustavo Saposnik Geert Jan Biessels Fergus N Doubal Myriam Fornage Philip B Gorelick Steven M Greenberg Randall T Higashida Scott E Kasner Sudha Seshadri

Stroke 2017 Feb 15;48(2):e44-e71. Epub 2016 Dec 15.

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http://dx.doi.org/10.1161/STR.0000000000000116DOI Listing
February 2017

Alzheimer's biomarkers in daily practice (ABIDE) project: Rationale and design.

Authors:
Arno de Wilde Ingrid S van Maurik Marleen Kunneman Femke Bouwman Marissa Zwan Eline A J Willemse Geert Jan Biessels Mirella Minkman Ruth Pel Niki S M Schoonenboom Ellen M A Smets Mike P Wattjes Frederik Barkhof Andrew Stephens Erik J van Lier Richard Batrla-Utermann Philip Scheltens Charlotte E Teunissen Bart N M van Berckel Wiesje M van der Flier

Alzheimers Dement (Amst) 2017 23;6:143-151. Epub 2017 Jan 23.

Department of Neurology & Alzheimer Center, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands; Department of Epidemiology and Biostatistics, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.dadm.2017.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318541PMC
January 2017

Microbleed and microinfarct detection in amyloid angiopathy: a high-resolution MRI-histopathology study.

Authors:
Susanne J van Veluw Andreas Charidimou Andre J van der Kouwe Arne Lauer Yael D Reijmer Isabel Costantino M Edip Gurol Geert Jan Biessels Matthew P Frosch Anand Viswanathan Steven M Greenberg

Brain 2016 12 19;139(Pt 12):3151-3162. Epub 2016 Sep 19.

1 J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1093/brain/aww229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840880PMC
December 2016

Quantification of deep medullary veins at 7 T brain MRI.

Authors:
Hugo J Kuijf Willem H Bouvy Jaco J M Zwanenburg Tom B Razoux Schultz Max A Viergever Koen L Vincken Geert Jan Biessels

Eur Radiol 2016 Oct 16;26(10):3412-8. Epub 2016 Feb 16.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s00330-016-4220-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021732PMC
October 2016

Perivascular spaces on 7 Tesla brain MRI are related to markers of small vessel disease but not to age or cardiovascular risk factors.

Authors:
Willem H Bouvy Jaco J M Zwanenburg Rik Reinink Laura E M Wisse Peter R Luijten L Jaap Kappelle Mirjam I Geerlings Geert Jan Biessels

J Cereb Blood Flow Metab 2016 10 6;36(10):1708-1717. Epub 2016 May 6.

Brain Center Rudolf Magnus, Department of Neurology, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1177/0271678X16648970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076789PMC
October 2016

Carotid stiffness is associated with impairment of cognitive performance in individuals with and without type 2 diabetes. The Maastricht Study.

Authors:
Stefan L C Geijselaers Simone J S Sep Miranda T Schram Martin P J van Boxtel Thomas T van Sloten Ronald M A Henry Koen D Reesink Abraham A Kroon Annemarie Koster Nicolaas C Schaper Pieter C Dagnelie Carla J H van der Kallen Geert Jan Biessels Coen D A Stehouwer

Atherosclerosis 2016 10 22;253:186-193. Epub 2016 Jul 22.

Department of Internal Medicine, Maastricht University Medical Centre +, Maastricht, The Netherlands; CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2016.07.912DOI Listing
October 2016

A Novel Imaging Marker for Small Vessel Disease Based on Skeletonization of White Matter Tracts and Diffusion Histograms.

Authors:
Ebru Baykara Benno Gesierich Ruth Adam Anil Man Tuladhar J Matthijs Biesbroek Huiberdina L Koek Stefan Ropele Eric Jouvent Hugues Chabriat Birgit Ertl-Wagner Michael Ewers Reinhold Schmidt Frank-Erik de Leeuw Geert Jan Biessels Martin Dichgans Marco Duering

Ann Neurol 2016 Oct 29;80(4):581-92. Epub 2016 Aug 29.

Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-University LMU, Munich, Germany.

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http://dx.doi.org/10.1002/ana.24758DOI Listing
October 2016

Risk Factors and Cognitive Relevance of Cortical Cerebral Microinfarcts in Patients With Ischemic Stroke or Transient Ischemic Attack.

Authors:
Zhaolu Wang Susanne J van Veluw Adrian Wong Wenyan Liu Lin Shi Jie Yang Yunyun Xiong Alexander Lau Geert Jan Biessels Vincent C T Mok

Stroke 2016 10 18;47(10):2450-5. Epub 2016 Aug 18.

From the Department of Medicine and Therapeutics (Z.W., A.W., W.L., L.S., A.L., V.C.T.M.), Therese Pei Fong Chow Research Centre for Prevention of Dementia (A.W., L.S., V.C.T.M.), Lui Che Woo Institute of Innovative Medicine (A.W., L.S., V.C.T.M.), The Chinese University of Hong Kong, China; Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, China (Z.W.); Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands (S.J.v.V., G.J.B.); Institute of Neuroscience and the Second Affiliated Hospital of Guangzhou Medical University and Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, China (J.Y.); and Department of Neurology, Jinling Hospital, Nanjing University School of Medicine, China (Y.X.).

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http://dx.doi.org/10.1161/STROKEAHA.115.012278DOI Listing
October 2016

Microbleeds on MRI are associated with microinfarcts on autopsy in cerebral amyloid angiopathy.

Authors:
Arne Lauer Susanne J van Veluw Christopher M William Andreas Charidimou Duangnapa Roongpiboonsopit Anastasia Vashkevich Alison Ayres Sergi Martinez-Ramirez Edip M Gurol Geert Jan Biessels Matthew Frosch Steven M Greenberg Anand Viswanathan

Neurology 2016 Oct 9;87(14):1488-1492. Epub 2016 Sep 9.

From the Hemorrhagic Stroke Research Program (A.L., S.J.v.V., A.C., D.R., A.V., A.A., S.M.-R., E.M.G., S.M.G., A.V.), Department of Neurology, Massachusetts General Hospital Stroke Research Center, Harvard Medical School, Boston; Department of Neurology (S.J.v.V., G.J.B.), Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands; Department of Pathology (C.M.W.), New York University Langone Medical Center, New York University School of Medicine; Department of Medicine (D.R.), Faculty of Medicine, Naresuan University, Phitsanulok, Thailand; and C.S. Kubik Laboratory for Neuropathology (M.F.), Massachusetts General Hospital, Harvard Medical School, Boston.

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http://dx.doi.org/10.1212/WNL.0000000000003184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075970PMC
October 2016

Determinants of leptomeningeal collateral flow in stroke patients with a middle cerebral artery occlusion.

Authors:
Tom van Seeters Geert Jan Biessels L Jaap Kappelle Yolanda van der Graaf Birgitta K Velthuis

Neuroradiology 2016 Oct 20;58(10):969-977. Epub 2016 Jul 20.

Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, HP E01 132, 3584 CX, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s00234-016-1727-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069303PMC
October 2016

Cortical cerebral microinfarcts on 3T MRI: A novel marker of cerebrovascular disease.

Authors:
Saima Hilal Emiel Sikking Muhammad Amin Shaik Qun Lin Chan Susanne J van Veluw Henri Vrooman Ching-Yu Cheng Charumathi Sabanayagam Carol Y Cheung Tien Yin Wong Narayanaswamy Venketasubramanian Geert Jan Biessels Christopher Chen Mohammad Kamran Ikram

Neurology 2016 Oct 2;87(15):1583-1590. Epub 2016 Sep 2.

From the Memory Ageing and Cognition Centre (S.H., M.A.S., Q.L.C., C.C., M.K.I.), National University Health System, Singapore; Department of Pharmacology (S.H., M.A.S., Q.L.C., C.C.), National University of Singapore; Department of Neurology (E.S., S.J.v.V., G.J.B., M.K.I.), Brain Center Rudolf Magnus, University Medical Center Utrecht; Departments of Radiology and Medical Informatics (H.V.) and Neurology and Epidemiology (M.K.I.), Erasmus University Medical Center, Rotterdam, the Netherlands; Singapore Eye Research Institute (C.-Y. Cheng, C.S., C.Y. Cheung, T.Y.W.), Singapore National Eye Center; Academic Medicine Research Institute (T.Y.W., M.K.I.), Duke-NUS Graduate Medical School; and Raffles Neuroscience Centre (N.V.), Raffles Hospital, Singapore.

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http://dx.doi.org/10.1212/WNL.0000000000003110DOI Listing
October 2016

The Prognostic Value of CT Angiography and CT Perfusion in Acute Ischemic Stroke.

Authors:
Tom van Seeters Geert Jan Biessels L Jaap Kappelle Irene C van der Schaaf Jan Willem Dankbaar Alexander D Horsch Joris M Niesten Merel J Luitse Charles B Majoie Jan Albert Vos Wouter J Schonewille Marianne A van Walderveen Marieke J Wermer Lucien E Duijm Koos Keizer Joseph C Bot Marieke C Visser Aad van der Lugt Diederik W Dippel F Oskar Kesselring Jeannette Hofmeijer Geert J Lycklama À Nijeholt Jelis Boiten Willem Jan van Rooij Paul L de Kort Yvo B Roos Ewoud J van Dijk C Constantijn Pleiter Willem P Mali Yolanda van der Graaf Birgitta K Velthuis

Cerebrovasc Dis 2015 21;40(5-6):258-69. Epub 2015 Oct 21.

Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1159/000441088DOI Listing
September 2016

MRBrainS Challenge: Online Evaluation Framework for Brain Image Segmentation in 3T MRI Scans.

Authors:
Adriënne M Mendrik Koen L Vincken Hugo J Kuijf Marcel Breeuwer Willem H Bouvy Jeroen de Bresser Amir Alansary Marleen de Bruijne Aaron Carass Ayman El-Baz Amod Jog Ranveer Katyal Ali R Khan Fedde van der Lijn Qaiser Mahmood Ryan Mukherjee Annegreet van Opbroek Sahil Paneri Sérgio Pereira Mikael Persson Martin Rajchl Duygu Sarikaya Örjan Smedby Carlos A Silva Henri A Vrooman Saurabh Vyas Chunliang Wang Liang Zhao Geert Jan Biessels Max A Viergever

Comput Intell Neurosci 2015 2;2015:813696. Epub 2015 Dec 2.

Image Sciences Institute, University Medical Center Utrecht, 3584 CX Utrecht, Netherlands.

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http://www.hindawi.com/journals/cin/2015/813696/
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http://dx.doi.org/10.1155/2015/813696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680055PMC
September 2016

The natural course of elevated levels of depressive symptoms in patients with vascular disease over eight years of follow-up. The SMART-Medea study.

Authors:
Minke Kooistra Yolanda van der Graaf Anne M Grool Nicolaas P A Zuithoff Geert Jan Biessels Mirjam I Geerlings

J Affect Disord 2016 Sep 24;202:95-101. Epub 2016 May 24.

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jad.2016.05.050DOI Listing
September 2016

Reproducibility and variability of quantitative magnetic resonance imaging markers in cerebral small vessel disease.

Authors:
François De Guio Eric Jouvent Geert Jan Biessels Sandra E Black Carol Brayne Christopher Chen Charlotte Cordonnier Frank-Eric De Leeuw Martin Dichgans Fergus Doubal Marco Duering Carole Dufouil Emrah Duzel Franz Fazekas Vladimir Hachinski M Arfan Ikram Jennifer Linn Paul M Matthews Bernard Mazoyer Vincent Mok Bo Norrving John T O'Brien Leonardo Pantoni Stefan Ropele Perminder Sachdev Reinhold Schmidt Sudha Seshadri Eric E Smith Luciano A Sposato Blossom Stephan Richard H Swartz Christophe Tzourio Mark van Buchem Aad van der Lugt Robert van Oostenbrugge Meike W Vernooij Anand Viswanathan David Werring Frank Wollenweber Joanna M Wardlaw Hugues Chabriat

J Cereb Blood Flow Metab 2016 08 11;36(8):1319-37. Epub 2016 May 11.

University Paris Diderot, Sorbonne Paris Cité, UMRS 1161 INSERM, Paris, France DHU NeuroVasc, Sorbonne Paris Cité, Paris, France Department of Neurology, AP-HP, Lariboisière Hospital, Paris, France

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http://dx.doi.org/10.1177/0271678X16647396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976752PMC
August 2016

Third European Stroke Science Workshop.

Authors:
Martin Dichgans Anna M Planas Geert Jan Biessels Bart van der Worp Cathie Sudlow Bo Norrving Kennedy Lees Heinrich P Mattle

Stroke 2016 07 9;47(7):e178-86. Epub 2016 Jun 9.

From the Institute for Stroke and Dementia Research, Klinikum der Universtität München, Ludwig-Maximilians University, Munich, Germany (M.D.); Munich Cluster for Systems Neurology (SyNergy), Munich, Germany (M.D.); Institutd' Investigacions Biomèdiques de Barcelona (IIBB), Consejo Superior de Investigaciones Científicas (CSIC), Institutd' Investigacions Biomèdiques August Pi iSunyer (IDIBAPS), Barcelona, Spain (A.M.P.); Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands (G.J.B., B.v.d.W.); Centre for Clinical Brain Sciences, Division of Clinical Neurosciences, University of Edinburgh, Edinburgh, United Kingdom (C.S.); Department of Clinical Sciences, Neurology, Lund University, Lund, Sweden (B.N.); Institute of Cardiovascular & Medical Sciences, University of Glasgow, Glasgow, United Kingdom (K.L.); and Department of Neurology, Inselspital, University of Bern, Bern, Switzerland (H.P.M.).

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http://dx.doi.org/10.1161/STROKEAHA.116.013516DOI Listing
July 2016

Diagnosis and treatment of vascular damage in dementia.

Authors:
Geert Jan Biessels

Biochim Biophys Acta 2016 05 22;1862(5):869-77. Epub 2015 Nov 22.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center, Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2015.11.009DOI Listing
May 2016

CT angiography and CT perfusion improve prediction of infarct volume in patients with anterior circulation stroke.

Authors:
Tom van Seeters Geert Jan Biessels L Jaap Kappelle Irene C van der Schaaf Jan Willem Dankbaar Alexander D Horsch Joris M Niesten Merel J A Luitse Charles B L M Majoie Jan Albert Vos Wouter J Schonewille Marianne A A van Walderveen Marieke J H Wermer Lucien E M Duijm Koos Keizer Joseph C J Bot Marieke C Visser Aad van der Lugt Diederik W J Dippel F Oskar H W Kesselring Jeannette Hofmeijer Geert J Lycklama À Nijeholt Jelis Boiten Willem Jan van Rooij Paul L M de Kort Yvo B W E M Roos Frederick J A Meijer C Constantijn Pleiter Willem P T M Mali Yolanda van der Graaf Birgitta K Velthuis

Neuroradiology 2016 Apr 14;58(4):327-37. Epub 2016 Jan 14.

Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, HP E01.132 3584 CX, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s00234-015-1636-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819789PMC
April 2016

Cerebral amyloid angiopathy severity is linked to dilation of juxtacortical perivascular spaces.

Authors:
Susanne J van Veluw Geert Jan Biessels Willem H Bouvy Wim Gm Spliet Jaco Jm Zwanenburg Peter R Luijten Eric A Macklin Annemieke Jm Rozemuller M Edip Gurol Steven M Greenberg Anand Viswanathan Sergi Martinez-Ramirez

J Cereb Blood Flow Metab 2016 Mar 7;36(3):576-80. Epub 2015 Dec 7.

J.P.K. Stroke Research Center, Department of Neurology, MGH, Boston, MA, USA.

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http://dx.doi.org/10.1177/0271678X15620434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794108PMC
March 2016

Heterogeneous histopathology of cortical microbleeds in cerebral amyloid angiopathy.

Authors:
Susanne J van Veluw Geert Jan Biessels Catharina J M Klijn Annemieke J M Rozemuller

Neurology 2016 Mar 3;86(9):867-71. Epub 2016 Feb 3.

From the Department of Neurology, Brain Center Rudolf Magnus (S.J.v.V., G.J.B., C.J.M.K.), and the Department of Pathology (A.J.M.R.), University Medical Center Utrecht; Department of Neurology, Donders Institute for Brain Cognition and Behaviour, Center for Neuroscience (C.J.M.K.), Radboud University Medical Center, Nijmegen; and Department of Pathology (A.J.M.R.), VU Medical Center, Amsterdam, the Netherlands.

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http://www.neurology.org/content/early/2016/02/03/WNL.000000
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http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000241
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http://dx.doi.org/10.1212/WNL.0000000000002419DOI Listing
March 2016

Peripheral glucose levels and cognitive outcome after ischemic stroke-Results from the Munich Stroke Cohort.

Authors:
Vera Zietemann Frank Arne Wollenweber Anna Bayer-Karpinska Geert Jan Biessels Martin Dichgans

Eur Stroke J 2016 Mar 1;1(1):51-60. Epub 2016 Mar 1.

Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität LMU, Munich, Germany.

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http://dx.doi.org/10.1177/2396987316631674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301221PMC
March 2016

First translational 'Think Tank' on cerebrovascular disease, cognitive impairment and dementia.

Authors:
Frank C Barone Deborah Gustafson Howard A Crystal Herman Moreno Mateusz G Adamski Ken Arai Alison E Baird Clotilde Balucani Adam M Brickman David Cechetto Philip Gorelick Geert Jan Biessels Amanda Kiliaan Lenore Launer Julie Schneider Farzaneh A Sorond Rachel Whitmer Clinton Wright Zheng Gang Zhang

J Transl Med 2016 Feb 13;14:50. Epub 2016 Feb 13.

Neurology, Henry Ford Hospital, Detroit, MI, USA.

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http://dx.doi.org/10.1186/s12967-016-0806-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752794PMC
February 2016

Potentials of incretin-based therapies in dementia and stroke in type 2 diabetes mellitus.

Authors:
Onno N Groeneveld L Jaap Kappelle Geert Jan Biessels

J Diabetes Investig 2016 Jan 3;7(1):5-16. Epub 2015 Oct 3.

University Medical Center Utrecht Brain Center Rudolf Magnus Department of Neurology Utrecht the Netherlands.

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http://dx.doi.org/10.1111/jdi.12420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718099PMC
January 2016

Genetic determinants of white matter hyperintensities and amyloid angiopathy in familial Alzheimer's disease.

Authors:
Natalie S Ryan Geert-Jan Biessels Lois Kim Jennifer M Nicholas Philip A Barber Phoebe Walsh Priya Gami Huw R Morris António J Bastos-Leite Jonathan M Schott Jon Beck Simon Mead Lucia Chavez-Gutierrez Bart de Strooper Martin N Rossor Tamas Revesz Tammaryn Lashley Nick C Fox

Neurobiol Aging 2015 Dec 4;36(12):3140-3151. Epub 2015 Sep 4.

Dementia Research Centre, Department of Neurodegenerative Diseases, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.08.026DOI Listing
December 2015

Hippocampal insulin resistance and cognitive dysfunction.

Authors:
Geert Jan Biessels Lawrence P Reagan

Nat Rev Neurosci 2015 Nov 14;16(11):660-71. Epub 2015 Oct 14.

Department of Pharmacology, Physiology and Neuroscience, University of South Carolina School of Medicine, 6439 Garners Ferry Road, VA Building 1, Room D40, Columbia, South Carolina 29208, USA.

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http://dx.doi.org/10.1038/nrn4019DOI Listing
November 2015

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images.

Authors:
Susanne J van Veluw Geert Jan Biessels Peter R Luijten Jaco J M Zwanenburg

J Vis Exp 2015 Nov 20(105). Epub 2015 Nov 20.

Department of Radiology, University Medical Center Utrecht.

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http://dx.doi.org/10.3791/53125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692739PMC
November 2015