Gautam Sethi

Gautam Sethi

UNVERIFIED PROFILE

Are you Gautam Sethi?   Register this Author

Register author
Gautam Sethi

Gautam Sethi

Publications by authors named "Gautam Sethi"

Are you Gautam Sethi?   Register this Author

100Publications

1015Reads

44Profile Views

A unique CDK4/6 inhibitor: Current and future therapeutic strategies of abemaciclib.

Pharmacol Res 2020 Jun 14;156:104686. Epub 2020 Feb 14.

Cancer Science Institute of Singapore, National University of Singapore, Singapore; Department of Haematology-Oncology, National University Cancer Institute Singapore, National University Health System, Singapore; Department of Pharmacology, National University of Singapore, Singapore; Department of Medicine, National University Cancer Institute Singapore, National University Health System, Singapore. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phrs.2020.104686DOI Listing
June 2020

The multifaceted role of reactive oxygen species in tumorigenesis.

Cell Mol Life Sci 2020 May 1. Epub 2020 May 1.

Amity Institute of Molecular Medicine and Stem Cell Research (AIMMSCR), Amity University Campus, Sector-125, Noida, Uttar Pradesh, 201313, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00018-020-03536-5DOI Listing
May 2020

Repurposing of drugs: An attractive pharmacological strategy for cancer therapeutics.

Semin Cancer Biol 2020 May 5. Epub 2020 May 5.

Amity Institute of Molecular Medicine and Stem cell Research (AIMMSCR), Amity University Uttar Pradesh, Noida, 201313, India. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.semcancer.2020.04.006DOI Listing
May 2020

Autophagy-modulating phytochemicals in cancer therapeutics: Current evidences and future perspectives.

Semin Cancer Biol 2020 May 22. Epub 2020 May 22.

Cancer and Cell Death Laboratory, Department of Life Science, National Institute of Technology, Rourkela 769008, Odisha, India. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.semcancer.2020.05.008DOI Listing
May 2020

Targeting STAT3 signaling pathway in cancer by agents derived from Mother Nature.

Semin Cancer Biol 2020 Apr 20. Epub 2020 Apr 20.

Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore 570006, India. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.semcancer.2020.03.016DOI Listing
April 2020

Circadian rhythm disruption and Alzheimer's disease: The dynamics of a vicious cycle.

Curr Neuropharmacol 2020 Apr 28. Epub 2020 Apr 28.

Neuropharmacology Laboratory, School of Pharmaceutical Sciences, Shoolini University, Solan 173 212, Himachal Pradesh. India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1570159X18666200429013041DOI Listing
April 2020

RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination.

Acta Pharmacol Sin 2020 Mar 23;41(3):394-403. Epub 2019 Oct 23.

Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41401-019-0309-6DOI Listing
March 2020

Piceatannol: A natural stilbene for the prevention and treatment of cancer.

Pharmacol Res 2020 03 8;153:104635. Epub 2020 Jan 8.

Cancer Biology Laboratory and DBT-AIST International Laboratory for Advanced Biomedicine (DAILAB), Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Assam, 781039, India. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phrs.2020.104635DOI Listing
March 2020

Molecular mechanisms of action of hesperidin in cancer: Recent trends and advancements.

Exp Biol Med (Maywood) 2020 Mar 12;245(5):486-497. Epub 2020 Feb 12.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1535370220903671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082885PMC
March 2020

Wnt signaling mediates TLR pathway and promote unrestrained adipogenesis and metaflammation: Therapeutic targets for obesity and type 2 diabetes.

Pharmacol Res 2020 02 14;152:104602. Epub 2019 Dec 14.

Department of Pharmacology and Therapeutics, School of Medicine, Faculty of Health and Medical Sciences, Taylor's University, Subang Jaya, Malaysia; Department of Pharmacology and Therapeutics, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Victoria, 3010, Australia; Malaysian Institute of Pharmaceuticals and Nutraceuticals (IPharm), Bukit Gambir, Gelugor, Pulau Pinang, Malaysia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phrs.2019.104602DOI Listing
February 2020

Curcumin Delivery Mediated by Bio-Based Nanoparticles: A Review.

Molecules 2020 Feb 6;25(3). Epub 2020 Feb 6.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules25030689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037405PMC
February 2020

Celastrol Alleviates Gamma Irradiation-Induced Damage by Modulating Diverse Inflammatory Mediators.

Int J Mol Sci 2020 Feb 6;21(3). Epub 2020 Feb 6.

Singapore Nuclear Research and Safety Initiative, National University of Singapore, Singapore 138602, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms21031084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036880PMC
February 2020

Plant lectins and their usage in preparing targeted nanovaccines for cancer immunotherapy.

Semin Cancer Biol 2020 Feb 14. Epub 2020 Feb 14.

Protein Biochemistry Research Laboratory, Dr. D. Y. Patil Biotechnology & Bioinformatics Institute, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Tathawade, Pune, 411033, Maharashtra, India. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.semcancer.2020.02.005DOI Listing
February 2020

Topoisomerase inhibitors: Pharmacology and emerging nanoscale delivery systems.

Pharmacol Res 2020 01 17;151:104551. Epub 2019 Nov 17.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phrs.2019.104551DOI Listing
January 2020

The vital role of ATP citrate lyase in chronic diseases.

J Mol Med (Berl) 2020 Jan 19;98(1):71-95. Epub 2019 Dec 19.

Cancer Biology Laboratory & DBT-AIST International Laboratory for Advanced Biomedicine (DAILAB), Department of Biosciences & Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam, 781039, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00109-019-01863-0DOI Listing
January 2020

Cytoskeletal Proteins in Cancer and Intracellular Stress: A Therapeutic Perspective.

Cancers (Basel) 2020 Jan 18;12(1). Epub 2020 Jan 18.

Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, 117593 Singapore, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cancers12010238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017214PMC
January 2020

Neuronal Development-Related miRNAs as Biomarkers for Alzheimer's disease, Depression, Schizophrenia and Ionizing Radiation Exposure.

Curr Med Chem 2020 Jan 21. Epub 2020 Jan 21.

Radiation Physiology Lab, Singapore Nuclear Research and Safety Initiative, National University of Singapore, CREATE Tower, Singapore 138602. Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/0929867327666200121122910DOI Listing
January 2020

Farnesol abrogates epithelial to mesenchymal transition process through regulating Akt/mTOR pathway.

Pharmacol Res 2019 12 31;150:104504. Epub 2019 Oct 31.

Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phrs.2019.104504DOI Listing
December 2019

The Emerging Role of Long Non-Coding RNAs in the Metastasis of Hepatocellular Carcinoma.

Biomolecules 2019 12 31;10(1). Epub 2019 Dec 31.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/biom10010066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023197PMC
December 2019

Role of Reactive Oxygen Species in Cancer Progression: Molecular Mechanisms and Recent Advancements.

Biomolecules 2019 11 13;9(11). Epub 2019 Nov 13.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/biom9110735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920770PMC
November 2019

The Emerging Roles of the HERC Ubiquitin Ligases in Cancer.

Curr Pharm Des 2018 ;24(15):1676-1681

Institute of Clinical Pharmacology, Guangzhou University of Chinese Medicine, 12 Jichang Road, Baiyun District, Guangzhou 510405, China.

View Article

Download full-text PDF

Source
http://www.eurekaselect.com/162478/article
Publisher Site
http://dx.doi.org/10.2174/1381612824666180528081024DOI Listing
October 2019

Engineering anti-cancer nanovaccine based on antigen cross-presentation.

Biosci Rep 2019 Oct;39(10)

Protein Biochemistry Research Laboratory, Dr. D.Y. Patil Biotechnology and Bioinformatics Institute, Dr. D.Y. Patil Vidyapeeth (Deemed to be University), Tathawade, Pune 411033, Maharashtra, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BSR20193220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822533PMC
October 2019

Anti-cancer effects of oxymatrine are mediated through multiple molecular mechanism(s) in tumor models.

Pharmacol Res 2019 09 5;147:104327. Epub 2019 Jul 5.

College of Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phrs.2019.104327DOI Listing
September 2019

The E-Cadherin and N-Cadherin Switch in Epithelial-to-Mesenchymal Transition: Signaling, Therapeutic Implications, and Challenges.

Cells 2019 09 20;8(10). Epub 2019 Sep 20.

School of Biosciences, Faculty of Health and Medical Sciences, Taylor's University, Subang Jaya 47500, Malaysia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cells8101118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830116PMC
September 2019

Nanoparticles Targeting STATs in Cancer Therapy.

Cells 2019 09 27;8(10). Epub 2019 Sep 27.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cells8101158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829305PMC
September 2019

Brusatol, a Nrf2 Inhibitor Targets STAT3 Signaling Cascade in Head and Neck Squamous Cell Carcinoma.

Biomolecules 2019 09 30;9(10). Epub 2019 Sep 30.

College of Korean Medicine, Kyung Hee University, #47, Kyungheedae-gil, Dongdaemoon-gu, Seoul 130-701, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/biom9100550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843503PMC
September 2019

Insights into Biological Role of LncRNAs in Epithelial-Mesenchymal Transition.

Cells 2019 09 30;8(10). Epub 2019 Sep 30.

School of Basic Medicine, Health Science Center, Yangtze University, Nanhuan Road, Jingzhou, Hubei 434023, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cells8101178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829226PMC
September 2019

Conditioned media from adipocytes promote proliferation, migration, and invasion in melanoma and colorectal cancer cells.

J Cell Physiol 2019 08 9;234(10):18249-18261. Epub 2019 Mar 9.

Department of Korean Pathology, College of Korean Medicine, Kyung Hee University, Kyungheedae-ro, Dongdaemun-gu, Seoul, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcp.28456DOI Listing
August 2019

Natural product-based nanoformulations for cancer therapy: Opportunities and challenges.

Semin Cancer Biol 2019 Aug 14. Epub 2019 Aug 14.

Lake Erie College of Osteopathic Medicine, Bradenton, FL 34211, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.semcancer.2019.08.014DOI Listing
August 2019

An Update on Pharmacological Potential of Boswellic Acids against Chronic Diseases.

Int J Mol Sci 2019 Aug 22;20(17). Epub 2019 Aug 22.

Cancer Biology Laboratory and DBT-AIST International Centre for Translational and Environmental Research(DAICENTER), Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Assam 781039, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms20174101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747466PMC
August 2019

Hydrogen Sulfide Prevents Elastin Loss and Attenuates Calcification Induced by High Glucose in Smooth Muscle Cells through Suppression of Stat3/Cathepsin S Signaling Pathway.

Int J Mol Sci 2019 Aug 27;20(17). Epub 2019 Aug 27.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms20174202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747320PMC
August 2019

Targeting STAT3 and oxidative phosphorylation in oncogene-addicted tumors.

Redox Biol 2019 07 13;25:101073. Epub 2018 Dec 13.

Department of Haematology-Oncology, National University Health System, Singapore; Haematology-Oncology Research Group, National University Cancer Institute of Singapore, National University Health System, Singapore; Cancer Science Institute, Singapore. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S22132317183090
Publisher Site
http://dx.doi.org/10.1016/j.redox.2018.101073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859582PMC
July 2019

A Brief Overview of the Antitumoral Actions of Leelamine.

Biomedicines 2019 Jul 19;7(3). Epub 2019 Jul 19.

College of Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/biomedicines7030053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783843PMC
July 2019

Casticin inhibits growth and enhances ionizing radiation-induced apoptosis through the suppression of STAT3 signaling cascade.

J Cell Biochem 2019 06 5;120(6):9787-9798. Epub 2018 Dec 5.

Department of Science in Korean Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcb.28259DOI Listing
June 2019

Cycloastragenol can negate constitutive STAT3 activation and promote paclitaxel-induced apoptosis in human gastric cancer cells.

Phytomedicine 2019 Jun 31;59:152907. Epub 2019 Mar 31.

Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phymed.2019.152907DOI Listing
June 2019

Honokiol for cancer therapeutics: A traditional medicine that can modulate multiple oncogenic targets.

Pharmacol Res 2019 06 17;144:192-209. Epub 2019 Apr 17.

Cancer Biology Laboratory and DBT-AIST International Laboratory for Advanced Biomedicine (DAILAB) Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Assam, 781039, India. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phrs.2019.04.004DOI Listing
June 2019

Functional interplay between YY1 and CARM1 promotes oral carcinogenesis.

Oncotarget 2019 Jun 4;10(38):3709-3724. Epub 2019 Jun 4.

Transcription and Disease Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore 560064, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.26984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557205PMC
June 2019

Intricate role of mitochondrial lipid in mitophagy and mitochondrial apoptosis: its implication in cancer therapeutics.

Cell Mol Life Sci 2019 May 11;76(9):1641-1652. Epub 2018 Dec 11.

Department of Life Science, National Institute of Technology Rourkela, Rourkela, Odisha, 769008, India.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00018-018-2990-x
Publisher Site
http://dx.doi.org/10.1007/s00018-018-2990-xDOI Listing
May 2019

Encapsulated human mesenchymal stem cells (eMSCs) as a novel anti-cancer agent targeting breast cancer stem cells: Development of 3D primed therapeutic MSCs.

Int J Biochem Cell Biol 2019 05 6;110:59-69. Epub 2019 Feb 6.

Division of Cancer Stem Cells and Cardiovascular Regeneration, School of Regenerative Medicine, Manipal Academy of Higher Education (MAHE), Bangalore, 560 065, India; Curtin Medical School, Curtin University, Perth, Western Australia, 6102, Australia; Cuor Stem Cellutions Pvt Ltd, School of Regenerative Medicine, Manipal Academy of Higher Education (MAHE), Bangalore, 560 065, India. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S13572725193003
Publisher Site
http://dx.doi.org/10.1016/j.biocel.2019.02.001DOI Listing
May 2019

Long non-coding RNAs are emerging targets of phytochemicals for cancer and other chronic diseases.

Cell Mol Life Sci 2019 May 16;76(10):1947-1966. Epub 2019 Mar 16.

Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, Uttar Pradesh, 221005, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00018-019-03053-0DOI Listing
May 2019

Targeting autophagy using natural compounds for cancer prevention and therapy.

Cancer 2019 04 12;125(8):1228-1246. Epub 2019 Feb 12.

Lake Erie College of Osteopathic Medicine, Bradenton, Florida.

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1002/cncr.31978
Publisher Site
http://dx.doi.org/10.1002/cncr.31978DOI Listing
April 2019

Brassinin Represses Invasive Potential of Lung Carcinoma Cells through Deactivation of PI3K/Akt/mTOR Signaling Cascade.

Molecules 2019 Apr 22;24(8). Epub 2019 Apr 22.

KHU-KIST Department of Converging Science and Technology, Kyung Hee University, Seoul 02447, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules24081584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514890PMC
April 2019

Oleuropein induces apoptosis via abrogating NF-κB activation cascade in estrogen receptor-negative breast cancer cells.

J Cell Biochem 2019 03 27;120(3):4504-4513. Epub 2018 Sep 27.

Radiobiology Research Laboratory, Singapore Nuclear Research and Safety Initiative, National University of Singapore, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcb.27738DOI Listing
March 2019

The expanding roles of long non-coding RNAs in the regulation of cancer stem cells.

Int J Biochem Cell Biol 2019 03 7;108:17-20. Epub 2019 Jan 7.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 117600, Singapore. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S13572725193000
Publisher Site
http://dx.doi.org/10.1016/j.biocel.2019.01.003DOI Listing
March 2019

Arctiin is a pharmacological inhibitor of STAT3 phosphorylation at tyrosine 705 residue and potentiates bortezomib-induced apoptotic and anti-angiogenic effects in human multiple myeloma cells.

Phytomedicine 2019 Mar 11;55:282-292. Epub 2018 Aug 11.

College of Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, South Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phymed.2018.06.038DOI Listing
March 2019

Inhibition of the deubiquitinase USP9x induces pre-B cell homeobox 1 (PBX1) degradation and thereby stimulates prostate cancer cell apoptosis.

J Biol Chem 2019 03 4;294(12):4572-4582. Epub 2019 Feb 4.

From the Key Laboratory of Protein Modification and Degradation, School of Basic Medical Sciences, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou 511436, China,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.RA118.006057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433065PMC
March 2019

Pleiotropic Pharmacological Actions of Capsazepine, a Synthetic Analogue of Capsaicin, against Various Cancers and Inflammatory Diseases.

Molecules 2019 Mar 12;24(5). Epub 2019 Mar 12.

KHU-KIST Department of Converging Science and Technology, Kyung Hee University, Seoul 02447, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules24050995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429077PMC
March 2019

Role of Natural Products in Modulating Histone Deacetylases in Cancer.

Molecules 2019 Mar 16;24(6). Epub 2019 Mar 16.

College of Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules24061047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471757PMC
March 2019

Potential of Zerumbone as an Anti-Cancer Agent.

Molecules 2019 Feb 18;24(4). Epub 2019 Feb 18.

Cancer Biology Laboratory, DBT-AIST International Laboratory for Advanced Biomedicine (DAILAB), Department of Biosciences & Bioengineering, Indian Institute of Technology, Guwahati, Assam 781039, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules24040734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413012PMC
February 2019

FBXW7 in Cancer: What Has Been Unraveled Thus Far?

Cancers (Basel) 2019 Feb 19;11(2). Epub 2019 Feb 19.

Cancer Biology Laboratory and DBT-AIST International Laboratory for Advanced Biomedicine (DAILAB), Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam-781039, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cancers11020246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406609PMC
February 2019

Casticin-Induced Inhibition of Cell Growth and Survival Are Mediated through the Dual Modulation of Akt/mTOR Signaling Cascade.

Cancers (Basel) 2019 Feb 22;11(2). Epub 2019 Feb 22.

Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea.

View Article

Download full-text PDF

Source
http://www.mdpi.com/2072-6694/11/2/254
Publisher Site
http://dx.doi.org/10.3390/cancers11020254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406334PMC
February 2019

Signal Transducer and Activator of Transcription (STATs) Proteins in Cancer and Inflammation: Functions and Therapeutic Implication.

Front Oncol 2019 21;9:48. Epub 2019 Feb 21.

School of Biosciences, Faculty of Health and Medical Sciences, Taylor's University, Subang Jaya, Malaysia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fonc.2019.00048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393348PMC
February 2019

Role of tumor-derived exosomes in cancer metastasis.

Biochim Biophys Acta Rev Cancer 2019 01 9;1871(1):12-19. Epub 2018 Nov 9.

Cancer Science Institute of Singapore, National University of Singapore, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 117600, Singapore. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0304419X183015
Publisher Site
http://dx.doi.org/10.1016/j.bbcan.2018.10.004DOI Listing
January 2019

Oxymatrine Attenuates Tumor Growth and Deactivates STAT5 Signaling in a Lung Cancer Xenograft Model.

Cancers (Basel) 2019 Jan 7;11(1). Epub 2019 Jan 7.

Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea.

View Article

Download full-text PDF

Source
http://www.mdpi.com/2072-6694/11/1/49
Publisher Site
http://dx.doi.org/10.3390/cancers11010049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356594PMC
January 2019

Sorcin a Potential Molecular Target for Cancer Therapy.

Transl Oncol 2018 Dec 11;11(6):1379-1389. Epub 2018 Sep 11.

Cancer Biology Laboratory, DBT-AIST International Laboratory for Advanced Biomedicine (DAILAB), Department of Biosciences & Bioengineering, Indian Institute of Technology Guwahati, Assam-781039, India. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tranon.2018.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134165PMC
December 2018

Dysregulation of Nrf2 in Hepatocellular Carcinoma: Role in Cancer Progression and Chemoresistance.

Cancers (Basel) 2018 Dec 3;10(12). Epub 2018 Dec 3.

Molecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore 641 046, Tamilnadu, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cancers10120481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315366PMC
December 2018

Pharmacological Utilization of Bergamottin, Derived from Grapefruits, in Cancer Prevention and Therapy.

Int J Mol Sci 2018 Dec 14;19(12). Epub 2018 Dec 14.

Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms19124048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321104PMC
December 2018

Stemness, Pluripotentiality, and Wnt Antagonism: sFRP4, a Wnt antagonist Mediates Pluripotency and Stemness in Glioblastoma.

Cancers (Basel) 2018 12 27;11(1). Epub 2018 Dec 27.

Division of Cancer Stem Cells and Cardiovascular and Neuronal Regeneration, School of Regenerative Medicine, Manipal Academy of Higher Education (MAHE), Bangalore 560 065, India.

View Article

Download full-text PDF

Source
http://www.mdpi.com/2072-6694/11/1/25
Publisher Site
http://dx.doi.org/10.3390/cancers11010025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356444PMC
December 2018

Ophiopogonin D, a Steroidal Glycoside Abrogates STAT3 Signaling Cascade and Exhibits Anti-Cancer Activity by Causing GSH/GSSG Imbalance in Lung Carcinoma.

Cancers (Basel) 2018 Nov 8;10(11). Epub 2018 Nov 8.

Department of Science in Korean Medicine, College of Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea.

View Article

Download full-text PDF

Source
http://www.mdpi.com/2072-6694/10/11/427
Publisher Site
http://dx.doi.org/10.3390/cancers10110427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265752PMC
November 2018

Traditional Chinese Medicine in Neuroprotection after Brain Insults with Special Reference to Radioprotection.

Evid Based Complement Alternat Med 2018 26;2018:2767208. Epub 2018 Nov 26.

Radiation Physiology Laboratory, Singapore Nuclear Research and Safety Initiative, National University of Singapore, 1 CREATE Way #04-01, CREATE Tower, Singapore 138602.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2018/2767208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287144PMC
November 2018

Hydrogen sulfide inhibits ATP-induced neuroinflammation and Aβ synthesis by suppressing the activation of STAT3 and cathepsin S.

Brain Behav Immun 2018 10 5;73:603-614. Epub 2018 Jul 5.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbi.2018.07.005DOI Listing
October 2018

Molecular Targets Modulated by Fangchinoline in Tumor Cells and Preclinical Models.

Molecules 2018 Oct 5;23(10). Epub 2018 Oct 5.

College of Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules23102538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222742PMC
October 2018

Potential Anti-Inflammatory and Anti-Cancer Properties of Farnesol.

Molecules 2018 Oct 31;23(11). Epub 2018 Oct 31.

Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea.

View Article

Download full-text PDF

Source
http://www.mdpi.com/1420-3049/23/11/2827
Publisher Site
http://dx.doi.org/10.3390/molecules23112827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278318PMC
October 2018

Slow Loris Trade in Vietnam: Exploring Diverse Knowledge and Values.

Folia Primatol (Basel) 2018 10;89(1):45-62. Epub 2018 Apr 10.

Faculty of Anthropology, Hanoi University of Social Science and Humanities, Vietnam National University, Hanoi, Vietnam.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000481196DOI Listing
September 2018

Formononetin-induced oxidative stress abrogates the activation of STAT3/5 signaling axis and suppresses the tumor growth in multiple myeloma preclinical model.

Cancer Lett 2018 09 29;431:123-141. Epub 2018 May 29.

College of Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, Republic of Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2018.05.038DOI Listing
September 2018

Novel tumor necrosis factor-α induced protein eight (TNFAIP8/TIPE) family: Functions and downstream targets involved in cancer progression.

Cancer Lett 2018 09 18;432:260-271. Epub 2018 Jun 18.

Cancer Biology Laboratory & DBT-AIST International Laboratory for Advanced Biomedicine (DAILAB), Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam, 781039, India. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2018.06.017DOI Listing
September 2018

The Role of Signal Transducer and Activator of Transcription 3 (STAT3) and Its Targeted Inhibition in Hematological Malignancies.

Cancers (Basel) 2018 Sep 13;10(9). Epub 2018 Sep 13.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore.

View Article

Download full-text PDF

Source
http://www.mdpi.com/2072-6694/10/9/327
Publisher Site
http://dx.doi.org/10.3390/cancers10090327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162647PMC
September 2018

TIPE Family of Proteins and Its Implications in Different Chronic Diseases.

Int J Mol Sci 2018 Sep 29;19(10). Epub 2018 Sep 29.

Cancer Biology Laboratory, DBT-AIST International Laboratory for Advanced Biomedicine (DAILAB), Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Assam 781039, India.

View Article

Download full-text PDF

Source
http://www.mdpi.com/1422-0067/19/10/2974
Publisher Site
http://dx.doi.org/10.3390/ijms19102974DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213092PMC
September 2018

Role of RNF20 in cancer development and progression - a comprehensive review.

Biosci Rep 2018 08 12;38(4). Epub 2018 Jul 12.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 117600 Singapore

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BSR20171287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043722PMC
August 2018

Magnolol: A Neolignan from the Magnolia Family for the Prevention and Treatment of Cancer.

Int J Mol Sci 2018 08 10;19(8). Epub 2018 Aug 10.

Cancer Biology Laboratory and DBT-AIST International Laboratory for Advanced Biomedicine (DAILAB), Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Assam 781039, India.

View Article

Download full-text PDF

Source
http://www.mdpi.com/1422-0067/19/8/2362
Publisher Site
http://dx.doi.org/10.3390/ijms19082362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121321PMC
August 2018

Possible use of Punica granatum (Pomegranate) in cancer therapy.

Pharmacol Res 2018 07 2;133:53-64. Epub 2018 May 2.

Cancer Biology Laboratory & DBT-AIST International Laboratory for Advanced Biomedicine (DAILAB), Department of Biosciences & Bioengineering, Indian Institute of Technology Guwahati, Assam 781039, India. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phrs.2018.04.021DOI Listing
July 2018

Potential role of genipin in cancer therapy.

Pharmacol Res 2018 07 24;133:195-200. Epub 2018 May 24.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 117600, Singapore. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phrs.2018.05.007DOI Listing
July 2018

Antioxidant response elements: Discovery, classes, regulation and potential applications.

Redox Biol 2018 07 7;17:297-314. Epub 2018 May 7.

Molecular Toxicology Laboratory, Department of Biotechnology, Bharathiar University, Coimbatore 641046, Tamilnadu, India. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.redox.2018.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007815PMC
July 2018

Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn.

Pharmacol Res 2018 07 21;133:213-214. Epub 2018 May 21.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore; School of Biomedical Sciences, Curtin Health Innovation Research Institute, Curtin University, Perth, WA 6009, Australia. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10436618183066
Publisher Site
http://dx.doi.org/10.1016/j.phrs.2018.05.004DOI Listing
July 2018

NGAL is Downregulated in Oral Squamous Cell Carcinoma and Leads to Increased Survival, Proliferation, Migration and Chemoresistance.

Cancers (Basel) 2018 Jul 10;10(7). Epub 2018 Jul 10.

Cancer Biology Laboratory & DBT-AIST International Laboratory for Advanced Biomedicine (DAILAB), Department of Biosciences & Bioengineering, Indian Institute of Technology Guwahati, Assam 781039, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cancers10070228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071146PMC
July 2018

Bergamottin Suppresses Metastasis of Lung Cancer Cells through Abrogation of Diverse Oncogenic Signaling Cascades and Epithelial-to-Mesenchymal Transition.

Molecules 2018 07 2;23(7). Epub 2018 Jul 2.

Department of Science in Korean Medicine, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules23071601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100248PMC
July 2018

Evidence for the Involvement of the Master Transcription Factor NF-κB in Cancer Initiation and Progression.

Biomedicines 2018 Jul 27;6(3). Epub 2018 Jul 27.

Institute of Molecular and Cellular Biology (A*STAR), 61 Biopolis Drive, Singapore 138673, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/biomedicines6030082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163404PMC
July 2018

Pro-Apoptotic and Anti-Cancer Properties of Diosgenin: A Comprehensive and Critical Review.

Nutrients 2018 05 19;10(5). Epub 2018 May 19.

Department of Pharmaceutical Sciences, College of Pharmacy, Larkin University, 18301 N. Miami Avenue, Miami, FL 33169, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nu10050645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986524PMC
May 2018

Correction: Role of novel histone modifications in cancer.

Oncotarget 2018 04 10;9(27):19460. Epub 2018 Apr 10.

Institute of Molecular and Cell Biology, ASTAR, Biopolis Drive, Proteos, Singapore, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.25152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922411PMC
April 2018

The Application of Embelin for Cancer Prevention and Therapy.

Molecules 2018 03 9;23(3). Epub 2018 Mar 9.

College of Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules23030621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017120PMC
March 2018

Role of novel histone modifications in cancer.

Oncotarget 2018 Feb 17;9(13):11414-11426. Epub 2017 Dec 17.

Institute of Molecular and Cell Biology, ASTAR, Biopolis Drive, Proteos, Singapore, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.23356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834259PMC
February 2018