Gauri Patwardhan

Gauri Patwardhan

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Gauri Patwardhan

Gauri Patwardhan

Publications by authors named "Gauri Patwardhan"

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18Publications

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Identification and Validation of a Novel Biologics Target in Triple Negative Breast Cancer.

Sci Rep 2019 Oct 17;9(1):14934. Epub 2019 Oct 17.

Department of Internal Medicine, Section of Medical Oncology, Yale Cancer Center, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1038/s41598-019-51453-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797726PMC
October 2019

Mitotic read-out genes confer poor outcome in luminal A breast cancer tumors.

Oncotarget 2017 Mar;8(13):21733-21740

Translational Research Unit, Albacete University Hospital and Centro Regional de Investigaciones Biomedicas (CRIB), Castilla La Mancha University, Albacete, Spain.

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http://dx.doi.org/10.18632/oncotarget.15562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400619PMC
March 2017

Systematic Drug Screening Identifies Tractable Targeted Combination Therapies in Triple-Negative Breast Cancer.

Cancer Res 2017 01 21;77(2):566-578. Epub 2016 Nov 21.

Department of Internal Medicine, Section of Medical Oncology, Yale School of Medicine, Yale University, New Haven, Connecticut.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-1901DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582957PMC
January 2017

Sphingolipids and mitochondrial apoptosis.

J Bioenerg Biomembr 2016 Apr;48(2):153-68

Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY, 40202, USA.

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http://dx.doi.org/10.1007/s10863-015-9602-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434644PMC
April 2016

Ceramide channels: destabilization by Bcl-xL and role in apoptosis.

Biochim Biophys Acta 2015 Oct 26;1848(10 Pt A):2374-84. Epub 2015 Jul 26.

Department of Biology, University of Maryland, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2015.07.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554889PMC
October 2015

Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells.

Biochim Biophys Acta 2014 Nov 6;1841(11):1571-80. Epub 2014 Sep 6.

Department of Basic Pharmaceutical Sciences, University of Louisiana at Monroe, Monroe, LA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2014.08.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188706PMC
November 2014

Glucosylceramide synthase, a factor in modulating drug resistance, is overexpressed in metastatic breast carcinoma.

Int J Oncol 2011 Aug 23;39(2):425-31. Epub 2011 May 23.

Department of Basic Pharmaceutical Sciences, University of Louisiana at Monroe, 700 University Avenue, Monroe, LA 71209, USA.

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http://dx.doi.org/10.3892/ijo.2011.1052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037863PMC
August 2011

Suppression of glucosylceramide synthase restores p53-dependent apoptosis in mutant p53 cancer cells.

Cancer Res 2011 Mar 28;71(6):2276-85. Epub 2011 Jan 28.

Department of Basic Pharmaceutical Sciences, University of Louisiana at Monroe, Monroe, Louisiana 71201, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-3107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059346PMC
March 2011

Sphingolipids and expression regulation of genes in cancer.

Prog Lipid Res 2011 Jan 21;50(1):104-14. Epub 2010 Oct 21.

Department of Basic Pharmaceutical Sciences, University of Louisiana at Monroe, 700 University Avenue, Monroe, LA 71209, USA.

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http://dx.doi.org/10.1016/j.plipres.2010.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012148PMC
January 2011

Mixed backbone antisense glucosylceramide synthase oligonucleotide (MBO-asGCS) loaded solid lipid nanoparticles: in vitro characterization and reversal of multidrug resistance in NCI/ADR-RES cells.

Int J Pharm 2010 Nov 15;400(1-2):251-9. Epub 2010 Sep 15.

Department of Basic Pharmaceutical Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, LA 71209-0497, United States.

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http://dx.doi.org/10.1016/j.ijpharm.2010.08.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952652PMC
November 2010

Direct assessment of P-glycoprotein efflux to determine tumor response to chemotherapy.

Biochem Pharmacol 2010 Jul 16;80(1):72-9. Epub 2010 Mar 16.

Department of Basic Pharmaceutical Sciences, University of Louisiana at Monroe, Monroe, LA 71209, USA.

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http://dx.doi.org/10.1016/j.bcp.2010.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860649PMC
July 2010

Direct quantitative determination of ceramide glycosylation in vivo: a new approach to evaluate cellular enzyme activity of glucosylceramide synthase.

J Lipid Res 2010 Apr 13;51(4):866-74. Epub 2009 Oct 13.

Department of Basic Pharmaceutical Sciences, University of Louisiana at Monroe, Monroe, LA, USA.

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http://dx.doi.org/10.1194/jlr.D002949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842142PMC
April 2010

A role for ceramide in driving cancer cell resistance to doxorubicin.

FASEB J 2008 Jul 1;22(7):2541-51. Epub 2008 Feb 1.

Department of Basic Pharmaceutical Sciences, University of Louisiana at Monroe, 700 University Ave., Monroe, LA 71209, USA.

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http://dx.doi.org/10.1096/fj.07-092981DOI Listing
July 2008