Publications by authors named "Gaston Mazandu"

39Publications

MSclassifier: median-supplement model-based classification tool for automated knowledge discovery.

F1000Res 2020 10;9:1114. Epub 2020 Sep 10.

African Institute for Mathematical Sciences and Computational Biology Division, Department of Integrative Biomedical Sciences, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.

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September 2020

Simulation of African and non-African low and high coverage whole genome sequence data to assess variant calling approaches.

Brief Bioinform 2020 Dec 21. Epub 2020 Dec 21.

Faculty of Health Sciences, Division of Human Genetics, Department of Pathology, University of Cape Town, Cape Town, South Africa.

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December 2020

IHP-PING-generating integrated human protein-protein interaction networks on-the-fly.

Brief Bioinform 2020 Oct 31. Epub 2020 Oct 31.

Computational Biology Division, Department of Integrative Biomedical Sciences, IDM, CIDRI-Africa WT Centre, University of Cape Town, Health Sciences Campus. Anzio Rd, Observatory, 7925, South Africa.

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October 2020

Identifying genetic variants and pathways associated with extreme levels of fetal hemoglobin in sickle cell disease in Tanzania.

BMC Med Genet 2020 06 5;21(1):125. Epub 2020 Jun 5.

Sickle Cell Program, Department of Hematology and Blood Transfusion, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.

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June 2020

A broad survey of DNA sequence data simulation tools.

Brief Funct Genomics 2020 01;19(1):49-59

Division of Human Genetics, Department of Pathology, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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January 2020

Computational/in silico methods in drug target and lead prediction.

Brief Bioinform 2020 09;21(5):1663-1675

Division of Human Genetics, Department of Pathology, University of Cape Town, Observatory 7925, South Africa.

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September 2020

Dissecting Mutation Prediction of Variants in African Genomes: Challenges and Perspectives.

Front Genet 2019 25;10:601. Epub 2019 Jun 25.

Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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June 2019

Hydroxyurea-Induced miRNA Expression in Sickle Cell Disease Patients in Africa.

Front Genet 2019 28;10:509. Epub 2019 May 28.

Division of Human Genetics, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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May 2019

Dating admixture events is unsolved problem in multi-way admixed populations.

Brief Bioinform 2018 11 19. Epub 2018 Nov 19.

Division of Human Genetics, Department of Pathology, Institute of Infectious Disease and Molecular Medicine,Faculty of Health Sciences, University of Cape Town, Observatory, Cape Town, South Africa.

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November 2018

A comprehensive survey of models for dissecting local ancestry deconvolution in human genome.

Brief Bioinform 2019 09;20(5):1709-1724

African Institute for Mathematical Sciences, Muizenberg, Cape Town 7945, South Africa.

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September 2019

Post genome-wide association analysis: dissecting computational pathway/network-based approaches.

Brief Bioinform 2019 03;20(2):690-700

Division of Human Genetics, Department of Pathology, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Private Bag, Rondebosch, 7700, Cape Town, South Africa; African Institute for Mathematical Sciences, 7945 Muizenberg, Cape Town, South Africa and Computational Biology Division, Department of Integrative Biomedical Sciences, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Medical School, Anzio Road, Observatory, 7925, Cape Town, South Africa.

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March 2019

A post-gene silencing bioinformatics protocol for plant-defence gene validation and underlying process identification: case study of the Arabidopsis thaliana NPR1.

BMC Plant Biol 2017 Nov 23;17(1):218. Epub 2017 Nov 23.

African Institute for Mathematical Sciences (AIMS), AIMS South Africa and AIMS Ghana, Cape Town, South Africa.

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November 2017

A multi-scenario genome-wide medical population genetics simulation framework.

Bioinformatics 2017 Oct;33(19):2995-3002

Department of Pathology, Division of Human Genetics, Faculty of Health Sciences, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory, Cape Town 7925, South Africa.

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October 2017