Gary S Gilkeson

Gary S Gilkeson

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Gary S Gilkeson

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Novel mechanism for estrogen receptor alpha modulation of murine lupus.

J Autoimmun 2019 Feb 8;97:59-69. Epub 2018 Nov 8.

Medical University of South Carolina, Division of Rheumatology and Immunology, Charleston, SC, 29425, USA; Ralph H. Johnson Veterans Affairs Hospital, Charleston, SC, 29425, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S08968411183051
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http://dx.doi.org/10.1016/j.jaut.2018.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351212PMC
February 2019

A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.

Hum Mol Genet 2018 Jul;27(13):2392-2404

Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1093/hmg/ddy140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005081PMC
July 2018

A Long-Term Follow-Up Study of Allogeneic Mesenchymal Stem/Stromal Cell Transplantation in Patients with Drug-Resistant Systemic Lupus Erythematosus.

Stem Cell Reports 2018 03 1;10(3):933-941. Epub 2018 Mar 1.

Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2018.01.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918528PMC
March 2018

Transancestral mapping and genetic load in systemic lupus erythematosus.

Authors:
Carl D Langefeld Hannah C Ainsworth Deborah S Cunninghame Graham Jennifer A Kelly Mary E Comeau Miranda C Marion Timothy D Howard Paula S Ramos Jennifer A Croker David L Morris Johanna K Sandling Jonas Carlsson Almlöf Eduardo M Acevedo-Vásquez Graciela S Alarcón Alejandra M Babini Vicente Baca Anders A Bengtsson Guillermo A Berbotto Marc Bijl Elizabeth E Brown Hermine I Brunner Mario H Cardiel Luis Catoggio Ricard Cervera Jorge M Cucho-Venegas Solbritt Rantapää Dahlqvist Sandra D'Alfonso Berta Martins Da Silva Iñigo de la Rúa Figueroa Andrea Doria Jeffrey C Edberg Emőke Endreffy Jorge A Esquivel-Valerio Paul R Fortin Barry I Freedman Johan Frostegård Mercedes A García Ignacio García de la Torre Gary S Gilkeson Dafna D Gladman Iva Gunnarsson Joel M Guthridge Jennifer L Huggins Judith A James Cees G M Kallenberg Diane L Kamen David R Karp Kenneth M Kaufman Leah C Kottyan László Kovács Helle Laustrup Bernard R Lauwerys Quan-Zhen Li Marco A Maradiaga-Ceceña Javier Martín Joseph M McCune David R McWilliams Joan T Merrill Pedro Miranda José F Moctezuma Swapan K Nath Timothy B Niewold Lorena Orozco Norberto Ortego-Centeno Michelle Petri Christian A Pineau Bernardo A Pons-Estel Janet Pope Prithvi Raj Rosalind Ramsey-Goldman John D Reveille Laurie P Russell José M Sabio Carlos A Aguilar-Salinas Hugo R Scherbarth Raffaella Scorza Michael F Seldin Christopher Sjöwall Elisabet Svenungsson Susan D Thompson Sergio M A Toloza Lennart Truedsson Teresa Tusié-Luna Carlos Vasconcelos Luis M Vilá Daniel J Wallace Michael H Weisman Joan E Wither Tushar Bhangale Jorge R Oksenberg John D Rioux Peter K Gregersen Ann-Christine Syvänen Lars Rönnblom Lindsey A Criswell Chaim O Jacob Kathy L Sivils Betty P Tsao Laura E Schanberg Timothy W Behrens Earl D Silverman Marta E Alarcón-Riquelme Robert P Kimberly John B Harley Edward K Wakeland Robert R Graham Patrick M Gaffney Timothy J Vyse

Nat Commun 2017 07 17;8:16021. Epub 2017 Jul 17.

Divisions of Genetics and Molecular Medicine and Immunology, Infection and Inflammatory Diseases, King's College London, Guy's Hospital, London SE1 9RT, UK.

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http://dx.doi.org/10.1038/ncomms16021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520018PMC
July 2017

Plasmacytoid dendritic cell distribution and maturation are altered in lupus prone mice prior to the onset of clinical disease.

Clin Immunol 2017 02 30;175:109-114. Epub 2016 Dec 30.

Division of Rheumatology and Immunology, Department of Medicine, 96 Jonathan Lucas Street, Suite 816, Medical University of South Carolina, Charleston, SC 29425, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2016.12.009DOI Listing
February 2017

X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome.

Arthritis Rheumatol 2016 05;68(5):1290-1300

College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

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http://dx.doi.org/10.1002/art.39560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019501PMC
May 2016

Early Ovariectomy Results in Reduced Numbers of CD11c+/CD11b+ Spleen Cells and Impacts Disease Expression in Murine Lupus.

Front Immunol 2016 15;7:31. Epub 2016 Feb 15.

Division of Rheumatology and Immunology, Ralph H. Johnson Veterans Affairs Hospital, Medical University of South Carolina , Charleston, SC , USA.

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http://dx.doi.org/10.3389/fimmu.2016.00031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753299PMC
February 2016

Estrogen Receptor α Deficiency Modulates TLR Ligand-Mediated PDC-TREM Expression in Plasmacytoid Dendritic Cells in Lupus-Prone Mice.

J Immunol 2015 Dec 9;195(12):5561-71. Epub 2015 Nov 9.

Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425; and Medical Research Service, Ralph H. Johnson Veterans Affairs Medical Center, Charleston, SC 29403

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http://dx.doi.org/10.4049/jimmunol.1500315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790076PMC
December 2015

Estrogen receptor alpha modulates mesangial cell responses to toll-like receptor ligands.

Am J Med Sci 2014 Dec;348(6):492-500

Medical Research Service, Ralph H. Johnson VAMC and the Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.

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http://dx.doi.org/10.1097/MAJ.0000000000000339DOI Listing
December 2014

Estrogen receptor alpha deficiency protects against development of cognitive impairment in murine lupus.

J Neuroinflammation 2014 Dec 16;11:171. Epub 2014 Dec 16.

Division of Rheumatology and Immunology, Department of Neurosciences, and Ralph H Johnson Veterans Affairs Hospital, Medical University of South Carolina, 96 Jonathan Lucas Street, Suite 814, MSC637, Charleston, SC, 29425, USA.

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http://dx.doi.org/10.1186/s12974-014-0171-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272530PMC
December 2014

Allogeneic mesenchymal stem cell transplantation for lupus nephritis patients refractory to conventional therapy.

Clin Rheumatol 2014 Nov 14;33(11):1611-9. Epub 2014 Aug 14.

Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing, Jiangsu, 210008, People's Republic of China.

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http://dx.doi.org/10.1007/s10067-014-2754-4DOI Listing
November 2014

Differential efficacy of human mesenchymal stem cells based on source of origin.

J Immunol 2014 Nov 1;193(9):4381-90. Epub 2014 Oct 1.

Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425; Medical Research Service, Ralph H. Johnson Veterans Affairs Medical Center, Charleston, SC 29403.

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1401636
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http://dx.doi.org/10.4049/jimmunol.1401636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201962PMC
November 2014

Pregnancy outcomes among African-American patients with systemic lupus erythematosus compared with controls.

Lupus Sci Med 2014 22;1(1):e000020. Epub 2014 Apr 22.

Division of Rheumatology, Department of Medicine , Medical University of South Carolina , Charleston, South Carolina , USA.

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http://dx.doi.org/10.1136/lupus-2014-000020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211631PMC
October 2014

Allogeneic mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus: 4 years of experience.

Cell Transplant 2013 ;22(12):2267-77

Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu, P. R. China.

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http://dx.doi.org/10.3727/096368911X582769cDOI Listing
August 2014

Endothelial nitric oxide synthase reduces crescentic and necrotic glomerular lesions, reactive oxygen production, and MCP1 production in murine lupus nephritis.

PLoS One 2013 31;8(5):e64650. Epub 2013 May 31.

Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0064650PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669382PMC
February 2014

Impact of sphingosine kinase 2 deficiency on the development of TNF-alpha-induced inflammatory arthritis.

Rheumatol Int 2013 Oct 3;33(10):2677-81. Epub 2012 Aug 3.

Departments of Microbiology and Immunology, 173 Ashley Avenue MSC 504 Room 203, Charleston, SC, 29425, USA.

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http://link.springer.com/10.1007/s00296-012-2493-2
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http://dx.doi.org/10.1007/s00296-012-2493-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784643PMC
October 2013

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.

Authors:
Keri L Monda Gary K Chen Kira C Taylor Cameron Palmer Todd L Edwards Leslie A Lange Maggie C Y Ng Adebowale A Adeyemo Matthew A Allison Lawrence F Bielak Guanjie Chen Mariaelisa Graff Marguerite R Irvin Suhn K Rhie Guo Li Yongmei Liu Youfang Liu Yingchang Lu Michael A Nalls Yan V Sun Mary K Wojczynski Lisa R Yanek Melinda C Aldrich Adeyinka Ademola Christopher I Amos Elisa V Bandera Cathryn H Bock Angela Britton Ulrich Broeckel Quiyin Cai Neil E Caporaso Chris S Carlson John Carpten Graham Casey Wei-Min Chen Fang Chen Yii-Der I Chen Charleston W K Chiang Gerhard A Coetzee Ellen Demerath Sandra L Deming-Halverson Ryan W Driver Patricia Dubbert Mary F Feitosa Ye Feng Barry I Freedman Elizabeth M Gillanders Omri Gottesman Xiuqing Guo Talin Haritunians Tamara Harris Curtis C Harris Anselm J M Hennis Dena G Hernandez Lorna H McNeill Timothy D Howard Barbara V Howard Virginia J Howard Karen C Johnson Sun J Kang Brendan J Keating Suzanne Kolb Lewis H Kuller Abdullah Kutlar Carl D Langefeld Guillaume Lettre Kurt Lohman Vaneet Lotay Helen Lyon Joann E Manson William Maixner Yan A Meng Kristine R Monroe Imran Morhason-Bello Adam B Murphy Josyf C Mychaleckyj Rajiv Nadukuru Katherine L Nathanson Uma Nayak Amidou N'diaye Barbara Nemesure Suh-Yuh Wu M Cristina Leske Christine Neslund-Dudas Marian Neuhouser Sarah Nyante Heather Ochs-Balcom Adesola Ogunniyi Temidayo O Ogundiran Oladosu Ojengbede Olufunmilayo I Olopade Julie R Palmer Edward A Ruiz-Narvaez Nicholette D Palmer Michael F Press Evandine Rampersaud Laura J Rasmussen-Torvik Jorge L Rodriguez-Gil Babatunde Salako Eric E Schadt Ann G Schwartz Daniel A Shriner David Siscovick Shad B Smith Sylvia Wassertheil-Smoller Elizabeth K Speliotes Margaret R Spitz Lara Sucheston Herman Taylor Bamidele O Tayo Margaret A Tucker David J Van Den Berg Digna R Velez Edwards Zhaoming Wang John K Wiencke Thomas W Winkler John S Witte Margaret Wrensch Xifeng Wu James J Yang Albert M Levin Taylor R Young Neil A Zakai Mary Cushman Krista A Zanetti Jing Hua Zhao Wei Zhao Yonglan Zheng Jie Zhou Regina G Ziegler Joseph M Zmuda Jyotika K Fernandes Gary S Gilkeson Diane L Kamen Kelly J Hunt Ida J Spruill Christine B Ambrosone Stefan Ambs Donna K Arnett Larry Atwood Diane M Becker Sonja I Berndt Leslie Bernstein William J Blot Ingrid B Borecki Erwin P Bottinger Donald W Bowden Gregory Burke Stephen J Chanock Richard S Cooper Jingzhong Ding David Duggan Michele K Evans Caroline Fox W Timothy Garvey Jonathan P Bradfield Hakon Hakonarson Struan F A Grant Ann Hsing Lisa Chu Jennifer J Hu Dezheng Huo Sue A Ingles Esther M John Joanne M Jordan Edmond K Kabagambe Sharon L R Kardia Rick A Kittles Phyllis J Goodman Eric A Klein Laurence N Kolonel Loic Le Marchand Simin Liu Barbara McKnight Robert C Millikan Thomas H Mosley Badri Padhukasahasram L Keoki Williams Sanjay R Patel Ulrike Peters Curtis A Pettaway Patricia A Peyser Bruce M Psaty Susan Redline Charles N Rotimi Benjamin A Rybicki Michèle M Sale Pamela J Schreiner Lisa B Signorello Andrew B Singleton Janet L Stanford Sara S Strom Michael J Thun Mara Vitolins Wei Zheng Jason H Moore Scott M Williams Shamika Ketkar Xiaofeng Zhu Alan B Zonderman Charles Kooperberg George J Papanicolaou Brian E Henderson Alex P Reiner Joel N Hirschhorn Ruth J F Loos Kari E North Christopher A Haiman

Nat Genet 2013 Jun 14;45(6):690-6. Epub 2013 Apr 14.

The Center for Observational Research, Amgen, Inc. Thousand Oaks, California, USA.

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http://dx.doi.org/10.1038/ng.2608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694490PMC
June 2013

Gene expression profile reveals abnormalities of multiple signaling pathways in mesenchymal stem cell derived from patients with systemic lupus erythematosus.

Clin Dev Immunol 2012 27;2012:826182. Epub 2012 Aug 27.

Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, 321 Zhongshan Road, Nanjing, Jiangsu 210008, China.

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https://www.hindawi.com/journals/jir/2012/826182/
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http://dx.doi.org/10.1155/2012/826182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433142PMC
January 2013

Mechanisms of tissue injury in lupus nephritis.

Arthritis Res Ther 2011 21;13(6):250. Epub 2011 Dec 21.

Department of Medicine, Division of Rheumatology, Medical University of South Carolina, 96 Jonathan Lucas St, CSB 912 MSC 637 Charleston, SC 29425-6370, USA.

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http://dx.doi.org/10.1186/ar3528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334648PMC
December 2012

Differential effect of allogeneic versus syngeneic mesenchymal stem cell transplantation in MRL/lpr and (NZB/NZW)F1 mice.

Clin Immunol 2012 Nov 17;145(2):142-52. Epub 2012 Sep 17.

Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu 210008, China.

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http://dx.doi.org/10.1016/j.clim.2012.08.012DOI Listing
November 2012

Multiple Autoantibodies Display Association with Lymphopenia, Proteinuria, and Cellular Casts in a Large, Ethnically Diverse SLE Patient Cohort.

Autoimmune Dis 2012 4;2012:819634. Epub 2012 Sep 4.

Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA ; Department of Medicine and Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

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http://dx.doi.org/10.1155/2012/819634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439936PMC
September 2012

Estrogen receptor alpha modulates Toll-like receptor signaling in murine lupus.

Clin Immunol 2012 Jul 20;144(1):1-12. Epub 2012 Apr 20.

Medical University of South Carolina, Division of Rheumatology and Immunology and Ralph H. Johnson Veterans Affairs Hospital, Charleston, SC 29425, USA.

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http://dx.doi.org/10.1016/j.clim.2012.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737583PMC
July 2012

Impact of sphingosine kinase on inflammatory pathways in fibroblast-like synoviocytes.

Inflamm Allergy Drug Targets 2011 Dec;10(6):464-71

Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, 29425, USA.

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December 2011

Increased expression of beta-arrestin 1 and 2 in murine models of rheumatoid arthritis: isoform specific regulation of inflammation.

Mol Immunol 2011 Oct 19;49(1-2):64-74. Epub 2011 Aug 19.

Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29425, United States.

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http://dx.doi.org/10.1016/j.molimm.2011.07.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205331PMC
October 2011

The dual role of complement in the progression of renal disease in NZB/W F(1) mice and alternative pathway inhibition.

Mol Immunol 2011 Oct 14;49(1-2):317-23. Epub 2011 Oct 14.

Department of Medicine, Division of Rheumatology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01615890110075
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http://dx.doi.org/10.1016/j.molimm.2011.09.015DOI Listing
October 2011

A GA microsatellite in the Fli1 promoter modulates gene expression and is associated with systemic lupus erythematosus patients without nephritis.

Arthritis Res Ther 2010 18;12(6):R212. Epub 2010 Nov 18.

Division of Rheumatology, Department of Medicine, Medical University of South Carolina, 96 Jonathon Lucas St, Charleston, SC 29425, USA.

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http://dx.doi.org/10.1186/ar3189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046520PMC
June 2011

Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus.

Arthritis Rheum 2010 Aug;62(8):2467-75

Department of Immunology and Rheumatology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing, Jiangsu 210008, China.

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http://dx.doi.org/10.1002/art.27548DOI Listing
August 2010

Genetic sphingosine kinase 1 deficiency significantly decreases synovial inflammation and joint erosions in murine TNF-alpha-induced arthritis.

J Immunol 2010 Aug 19;185(4):2570-9. Epub 2010 Jul 19.

Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA.

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http://dx.doi.org/10.4049/jimmunol.1000644DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2942019PMC
August 2010

Allogenic mesenchymal stem cells transplantation in refractory systemic lupus erythematosus: a pilot clinical study.

Ann Rheum Dis 2010 Aug;69(8):1423-9

Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.

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http://ard.bmj.com/cgi/doi/10.1136/ard.2009.123463
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http://dx.doi.org/10.1136/ard.2009.123463DOI Listing
August 2010

The impact of vitamin D on dendritic cell function in patients with systemic lupus erythematosus.

PLoS One 2010 Feb 16;5(2):e9193. Epub 2010 Feb 16.

Division of Autoimmune and Musculoskeletal Disease, Feinstein Institute for Medical Research, Manhasset, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0009193PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821911PMC
February 2010

The impact of systemic lupus erythematosus on employment.

J Rheumatol 2009 Nov 27;36(11):2470-5. Epub 2009 Feb 27.

Medical University of South Carolina, Division of Rheumatology and Immunology, Charleston, South Carolina 29425, USA.

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http://dx.doi.org/10.3899/jrheum.080586DOI Listing
November 2009

A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration.

Invest Ophthalmol Vis Sci 2009 Jul 5;50(7):3056-64. Epub 2009 Mar 5.

Department of Neurosciences, Division of Research, Medical University of South Carolina, Charleston, South Carolina 29425, USA.

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http://dx.doi.org/10.1167/iovs.08-2222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908507PMC
July 2009

Assessment of trichloroethylene (TCE) exposure in murine strains genetically-prone and non-prone to develop autoimmune disease.

J Environ Sci Health A Tox Hazard Subst Environ Eng 2009 Apr;44(5):443-53

Clinical Laboratory Sciences Program, University of Nevada-Las Vegas, Las Vegas, Nevada, USA.

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http://www.tandfonline.com/doi/abs/10.1080/10934520902719738
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http://dx.doi.org/10.1080/10934520902719738DOI Listing
April 2009

N,N,-diethyl-m-toluamide (DEET) suppresses humoral immunological function in B6C3F1 mice.

Toxicol Sci 2009 Mar 13;108(1):110-23. Epub 2009 Jan 13.

Clinical Laboratory Sciences, University of Nevada-Las Vegas, Las Vegas, Nevada 89154, USA.

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https://academic.oup.com/toxsci/article-lookup/doi/10.1093/t
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http://dx.doi.org/10.1093/toxsci/kfp001DOI Listing
March 2009

A role for sphingosine kinase 1 in dextran sulfate sodium-induced colitis.

FASEB J 2009 Jan 24;23(1):143-52. Epub 2008 Sep 24.

Department of Medicine, Medical University of South Carolina, 114 Doughty St., MSC 779, Charleston, SC 29425, USA.

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http://dx.doi.org/10.1096/fj.08-118109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626622PMC
January 2009

Lifetime exposure to trichloroethylene (TCE) does not accelerate autoimmune disease in MRL +/+ mice.

J Environ Sci Health A Tox Hazard Subst Environ Eng 2008 Oct;43(12):1402-9

Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina 29412, USA.

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http://dx.doi.org/10.1080/10934520802232063DOI Listing
October 2008

Inducible nitric oxide synthase inhibitor SD-3651 reduces proteinuria in MRL/lpr mice deficient in the NOS2 gene.

J Investig Med 2008 Oct;56(7):911-9

Department of Medicine, Division of Rheumatology, Medical University of South Carolina, 96 Jonathan Lucas Street, Charleston, SC 29525, USA.

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http://jim.bmj.com/lookup/doi/10.2310/JIM.0b013e3181889e13
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http://dx.doi.org/10.2310/JIM.0b013e3181889e13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637653PMC
October 2008

The histone deacetylase inhibitor trichostatin A upregulates regulatory T cells and modulates autoimmunity in NZB/W F1 mice.

J Autoimmun 2008 Sep 23;31(2):123-30. Epub 2008 Jul 23.

Department of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, VA, USA.

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http://dx.doi.org/10.1016/j.jaut.2008.04.020DOI Listing
September 2008

Impact of estrogen receptor deficiency on disease expression in the NZM2410 lupus prone mouse.

Clin Immunol 2008 Aug 29;128(2):259-68. Epub 2008 May 29.

Medical University of South Carolina, 96 Jonathan Lucas Street, Suite 912, PO Box 250637, Charleston, SC 29425, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S152166160800605
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http://dx.doi.org/10.1016/j.clim.2008.03.508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778964PMC
August 2008

The transcription factor Fli-1 modulates marginal zone and follicular B cell development in mice.

J Immunol 2008 Aug;181(3):1644-54

Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504761PMC
http://dx.doi.org/10.4049/jimmunol.181.3.1644DOI Listing
August 2008

Suppression of humoral immunity in mice following exposure to perfluorooctane sulfonate.

Toxicol Sci 2008 Jul 20;104(1):144-54. Epub 2008 Mar 20.

Department of Pediatrics, Medical,University of South Carolina, Charleston, South Carolina 29412, USA.

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http://dx.doi.org/10.1093/toxsci/kfn059DOI Listing
July 2008

Ethnic disparities among patients with systemic lupus erythematosus in South Carolina.

J Rheumatol 2008 May 15;35(5):819-25. Epub 2008 Mar 15.

Division of Rheumatology and Immunology, Medical University of South Carolina, Charleston, South Carolina 29425, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670803PMC
May 2008

Autoantibody prevalence and lupus characteristics in a unique African American population.

Arthritis Rheum 2008 May;58(5):1237-47

Division of Rheumatology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA.

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http://dx.doi.org/10.1002/art.23416DOI Listing
May 2008

Two aspects of the clinical and humanistic burden of systemic lupus erythematosus: mortality risk and quality of life early in the course of disease.

Arthritis Rheum 2008 Apr;59(4):458-64

Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.1002/art.23539DOI Listing
April 2008

Low-dose targeted complement inhibition protects against renal disease and other manifestations of autoimmune disease in MRL/lpr mice.

J Immunol 2008 Jan;180(2):1231-8

Department of Microbiology and Immunology and Children's Research Institute, Medical University ofSouth Carolina, Charleston 29425, USA.

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http://dx.doi.org/10.4049/jimmunol.180.2.1231DOI Listing
January 2008