Gary Gilbert

Gary Gilbert

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Gary Gilbert

Gary Gilbert

Publications by authors named "Gary Gilbert"

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The evolving understanding of factor VIII binding sites and implications for the treatment of hemophilia A.

Authors:
Gary E Gilbert

Blood Rev 2019 01 24;33:1-5. Epub 2018 May 24.

VA Boston Healthcare System, Harvard Medical School, Boston, MA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.blre.2018.05.001DOI Listing
January 2019

A microengineered vascularized bleeding model that integrates the principal components of hemostasis.

Nat Commun 2018 02 6;9(1):509. Epub 2018 Feb 6.

Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 345 Ferst Drive, Atlanta, GA, 30332, USA.

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http://dx.doi.org/10.1038/s41467-018-02990-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802762PMC
February 2018

Inhibitory antibodies against factor VIII C1 domain.

Authors:
Gary E Gilbert

Blood 2016 10;128(16):2001-2002

VA BOSTON HEALTHCARE SYSTEM; HARVARD MEDICAL SCHOOL.

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http://dx.doi.org/10.1182/blood-2016-08-727818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073179PMC
October 2016

Platelet binding sites for factor VIII in relation to fibrin and phosphatidylserine.

Blood 2015 Sep 10;126(10):1237-44. Epub 2015 Jul 10.

Departments of Pediatrics and Pathology, University of Michigan, Ann Arbor, MI.

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http://dx.doi.org/10.1182/blood-2015-01-620245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559935PMC
September 2015

Lactadherin inhibits secretory phospholipase A2 activity on pre-apoptotic leukemia cells.

PLoS One 2013 23;8(10):e77143. Epub 2013 Oct 23.

Department of Molecular Biology, Aarhus University, Aarhus C, Denmark ; Departments of Medicine, Veterans Administration Boston Healthcare System, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077143PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806724PMC
February 2015

Changes in the Factor VIII C2 domain upon membrane binding determined by hydrogen-deuterium exchange MS.

Biochem J 2014 Aug;461(3):443-51

*Medicine Departments of VA Boston Healthcare System, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02132, U.S.A.

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http://dx.doi.org/10.1042/BJ20140121DOI Listing
August 2014

Factor VIII inhibitor epitopes and an enigma.

Authors:
Gary E Gilbert

Blood 2013 Dec;122(26):4160-1

VA BOSTON HEALTHCARE SYSTEM;

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http://dx.doi.org/10.1182/blood-2013-10-531822DOI Listing
December 2013

Endothelial cell phagocytosis of senescent neutrophils decreases procoagulant activity.

Thromb Haemost 2013 Jun 4;109(6):1079-90. Epub 2013 Apr 4.

Department of Medicine, The First Affiliated Hospital, Harbin Medical University, 23 Youzheng Street, Nangang District, Harbin 150001, China.

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http://dx.doi.org/10.1160/TH12-12-0894DOI Listing
June 2013

Backbone resonance assignments of the C2 domain of coagulation factor VIII.

Biomol NMR Assign 2013 Apr 6;7(1):31-4. Epub 2012 Mar 6.

Department of Chemistry, University of Illinois at Urbana-Champaign, 600 S Mathews Ave, Urbana, IL 61801, USA.

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http://dx.doi.org/10.1007/s12104-012-9370-5DOI Listing
April 2013

Conservative mutations in the C2 domains of factor VIII and factor V alter phospholipid binding and cofactor activity.

Blood 2012 Aug 21;120(9):1923-32. Epub 2012 May 21.

Department of Medicine, Veterans Administration Boston Healthcare System, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1182/blood-2012-01-408245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433094PMC
August 2012

Lactadherin binds to phosphatidylserine-containing vesicles in a two-step mechanism sensitive to vesicle size and composition.

Biochim Biophys Acta 2012 Apr 2;1818(4):1019-27. Epub 2011 Sep 2.

Interdisciplinary Nanoscience Center, Aarhus University, Gustav Wieds Vej 10C, DK-8000 Aarhus C, Denmark.

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http://dx.doi.org/10.1016/j.bbamem.2011.08.032DOI Listing
April 2012

Phagocytosis by macrophages and endothelial cells inhibits procoagulant and fibrinolytic activity of acute promyelocytic leukemia cells.

Blood 2012 Mar 2;119(10):2325-34. Epub 2011 Dec 2.

Health Ministry Key Laboratory of Cell Transplantation, Heilongjiang Institute of Hematology and Oncology, Department of Hematology, The First Affiliated Hospital, Harbin Medical University, China.

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http://dx.doi.org/10.1182/blood-2011-06-362186DOI Listing
March 2012

Curbing an inhibitor for hemostasis.

Blood 2011 May;117(20):5277-8

VA Boston Healthcare System.

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http://dx.doi.org/10.1182/blood-2011-03-342725DOI Listing
May 2011

Membrane-binding properties of the Factor VIII C2 domain.

Biochem J 2011 Apr;435(1):187-96

Department of Medicine, Veterans Affairs Boston Healthcare System, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02132, USA.

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http://dx.doi.org/10.1042/BJ20101797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670696PMC
April 2011

A membrane-interactive surface on the factor VIII C1 domain cooperates with the C2 domain for cofactor function.

Blood 2011 Mar 14;117(11):3181-9. Epub 2010 Dec 14.

Department of Medicine, Veterans Administration Boston Healthcare System, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1182/blood-2010-08-301663DOI Listing
March 2011

Daunorubicin induces procoagulant activity of cultured endothelial cells through phosphatidylserine exposure and microparticles release.

Thromb Haemost 2010 Dec 30;104(6):1235-41. Epub 2010 Sep 30.

Department of Hematology, The First Affiliated Hospital, Harbin Medical University, Harbin, China.

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http://dx.doi.org/10.1160/TH10-02-0102DOI Listing
December 2010

Daunorubicin induces procoagulant response through phosphatidylserine exposure in red blood cells.

Thromb Res 2010 Feb 2;125(2):178-83. Epub 2009 Oct 2.

Department of Hematology, First Affiliated Hospital, Harbin Medical University, Harbin 150001, China.

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https://linkinghub.elsevier.com/retrieve/pii/S00493848090039
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http://dx.doi.org/10.1016/j.thromres.2009.09.006DOI Listing
February 2010

Bovine lactadherin as a calcium-independent imaging agent of phosphatidylserine expressed on the surface of apoptotic HeLa cells.

J Histochem Cytochem 2009 Oct 22;57(10):907-14. Epub 2009 Jun 22.

Protein Chemistry Laboratory, Milk Protein Research Consortium, Department of Molecular Biology, University of Aarhus, Aarhus, Denmark.

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http://dx.doi.org/10.1369/jhc.2009.953729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746724PMC
October 2009

Factor VIII C1 domain residues Lys 2092 and Phe 2093 contribute to membrane binding and cofactor activity.

Blood 2009 Oct 17;114(18):3938-46. Epub 2009 Aug 17.

Department of Plasma Proteins, Sanquin Research, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2009-01-197707DOI Listing
October 2009

Procoagulant activity and phosphatidylserine of amniotic fluid cells.

Thromb Haemost 2009 May;101(5):845-51

Division of Hematology, Department of Medicine, The First Affiliated Hospital, Harbin Medical University, Harbin, China, 150001.

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May 2009

Where does von Willebrand factor go?

Authors:
Gary E Gilbert

Blood 2008 Sep;112(5):1549-50

VA Boston Healthcare System, USA.

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http://dx.doi.org/10.1182/blood-2008-07-167742DOI Listing
September 2008

How to pass information and deliver energy to a network of implantable devices within the human body.

Conf Proc IEEE Eng Med Biol Soc 2007 ;2007:5286-9

Laboratory for Computational Neuroscience, Department of Neurosurgery, University of Pittsburgh, Pittsburgh, PA 15260, USA.

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http://dx.doi.org/10.1109/IEMBS.2007.4353534DOI Listing
March 2008

Crystal structure of lactadherin C2 domain at 1.7A resolution with mutational and computational analyses of its membrane-binding motif.

J Biol Chem 2008 Mar 26;283(11):7230-41. Epub 2007 Dec 26.

Department of Physiology and Biophysics, Boston University School of Medicine, Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.1074/jbc.M705195200DOI Listing
March 2008

Membrane phosphatidylserine regulates surface charge and protein localization.

Science 2008 Jan;319(5860):210-3

Division of Cell Biology, Hospital for Sick Children, Toronto M5G 1X8, Canada.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1152066
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http://dx.doi.org/10.1126/science.1152066DOI Listing
January 2008

An overview of 3D video transmission and display technologies for telemedicine applications.

Stud Health Technol Inform 2007 ;125:298-303

Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA.

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May 2007

Design of the next-generation medical implants with communication energy and ports.

Stud Health Technol Inform 2007 ;125:457-9

Laboratory for Computational Neuroscience, Department of Neurosurgery, University of Pittsburgh, Pittsburgh, PA 15260, USA.

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May 2007

Lactadherin detects early phosphatidylserine exposure on immortalized leukemia cells undergoing programmed cell death.

Cytometry A 2006 Dec;69(12):1193-201

Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/cyto.a.20345DOI Listing
December 2006

Simulation training in the obstetrics and gynecology clerkship.

Am J Obstet Gynecol 2006 Nov 17;195(5):1489-92. Epub 2006 Jul 17.

Department of Obstetrics and Gynecology, Joan C. Edwards School of Medicine at Marshall University, Huntington, WV 25701, USA.

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http://dx.doi.org/10.1016/j.ajog.2006.05.003DOI Listing
November 2006

Simple model of the optical characteristics of bubbles and sediments in seawater of the surf zone.

Appl Opt 2006 Sep;45(25):6577-85

B.I. Stepanov Institute of Physics, National Academy of Sciences of Belarus, Minsk, Belarus.

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http://dx.doi.org/10.1364/ao.45.006577DOI Listing
September 2006

The future of military medicine has not arrived yet, but we can see it from here.

Telemed J E Health 2006 Aug;12(4):417-25

HQ U.S. Army Medical Research and Materiel Command. Fort Detrick, Maryland 21702, USA.

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http://dx.doi.org/10.1089/tmj.2006.12.417DOI Listing
August 2006

Use of microsphere-supported phospholipid membranes for analysis of protein-lipid interactions.

Authors:
Gary E Gilbert

Curr Protoc Cytom 2005 Nov;Chapter 13:Unit13.3

Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/0471142956.cy1303s34DOI Listing
November 2005

Telemedicine standardization in the NATO environment.

Telemed J E Health 2004 ;10(4):459-65

Charles McC. Mathias National Study Center for Trauma and Emergency Medical Systems, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1089/tmj.2004.10.459DOI Listing
March 2005

Lysine 5 and phenylalanine 9 of the factor IX omega-loop interact with phosphatidylserine in a membrane-mimetic environment.

Biochemistry 2004 Dec;43(49):15367-78

Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center, Department of Medicine, Harvard Medical School, 330 Brookline Avenue, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1021/bi049107fDOI Listing
December 2004

Lactadherin binds selectively to membranes containing phosphatidyl-L-serine and increased curvature.

Biochim Biophys Acta 2004 Nov;1667(1):82-90

Department of Medicine, VA Boston Healthcare System, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02132, USA.

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http://dx.doi.org/10.1016/j.bbamem.2004.09.006DOI Listing
November 2004

"SMART" technologies for anti-terrorism and homeland security.

Telemed J E Health 2003 ;9(2):223-6

Telemedicine and Advanced Technology Research Center (TATRC), Fort Detrick, Maryland 21702-5012, USA.

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http://dx.doi.org/10.1089/153056203766437561DOI Listing
August 2003

Lactadherin inhibits enzyme complexes of blood coagulation by competing for phospholipid-binding sites.

Blood 2003 Apr 27;101(7):2628-36. Epub 2002 Nov 27.

Department of Medicine, VA Boston Healthcare System, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1182/blood-2002-07-1951DOI Listing
April 2003

Military research needs in biomedical informatics.

J Am Med Inform Assoc 2002 Sep-Oct;9(5):509-19

Telemedicine and Advanced Technology Research Center, Fort Detrick, MD 21702-5012, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC346638PMC
http://dx.doi.org/10.1197/jamia.m1044DOI Listing
October 2002

Four hydrophobic amino acids of the factor VIII C2 domain are constituents of both the membrane-binding and von Willebrand factor-binding motifs.

J Biol Chem 2002 Feb 6;277(8):6374-81. Epub 2001 Nov 6.

Veterans Affairs Boston Healthcare System, Brigham and Women's Hospital, and Harvard Medical School, West Roxbury, Massachusetts 02132, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M104732200
Publisher Site
http://dx.doi.org/10.1074/jbc.M104732200DOI Listing
February 2002