Gary A Splitter

Gary A Splitter

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Gary A Splitter

Gary A Splitter

Publications by authors named "Gary A Splitter"

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35Publications

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Let There Be Light! Bioluminescent Imaging to Study Bacterial Pathogenesis in Live Animals and Plants.

Adv Biochem Eng Biotechnol 2016 ;154:119-45

Ohio Agricultural Research and Development Center, Department of Veterinary Preventive Medicine, The Ohio State University, Wooster, OH, 44691, USA.

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http://dx.doi.org/10.1007/10_2014_280DOI Listing
September 2018

Brucella Peptide Cross-Reactive Major Histocompatibility Complex Class I Presentation Activates SIINFEKL-Specific T Cell Receptor-Expressing T Cells.

Infect Immun 2018 07 21;86(7). Epub 2018 Jun 21.

Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA

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http://dx.doi.org/10.1128/IAI.00281-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013681PMC
July 2018

The Bacterial Second Messenger Cyclic di-GMP Regulates Brucella Pathogenesis and Leads to Altered Host Immune Response.

Infect Immun 2016 Dec 18;84(12):3458-3470. Epub 2016 Nov 18.

Department of Pediatrics, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.

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http://dx.doi.org/10.1128/IAI.00531-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116723PMC
December 2016

CD8+ T cell exhaustion, suppressed gamma interferon production, and delayed memory response induced by chronic Brucella melitensis infection.

Infect Immun 2015 Dec 28;83(12):4759-71. Epub 2015 Sep 28.

Department of Pathobiological Sciences, University of Wisconsin-Madison School of Veterinary Medicine, Madison, Wisconsin, USA

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http://iai.asm.org/lookup/doi/10.1128/IAI.01184-15
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http://dx.doi.org/10.1128/IAI.01184-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645381PMC
December 2015

Brucella induces an unfolded protein response via TcpB that supports intracellular replication in macrophages.

PLoS Pathog 2013 5;9(12):e1003785. Epub 2013 Dec 5.

Department of Pediatrics, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1003785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855547PMC
September 2014

Osteoarticular tissue infection and development of skeletal pathology in murine brucellosis.

Dis Model Mech 2013 May 8;6(3):811-8. Epub 2013 Mar 8.

Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA.

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http://dx.doi.org/10.1242/dmm.011056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634663PMC
May 2013

Modulation of host microtubule dynamics by pathogenic bacteria.

Biomol Concepts 2012 Dec;3(6):571-580

Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA.

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http://dx.doi.org/10.1515/bmc-2012-0030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625037PMC
December 2012

Active evasion of CTL mediated killing and low quality responding CD8+ T cells contribute to persistence of brucellosis.

PLoS One 2012 25;7(4):e34925. Epub 2012 Apr 25.

Department of Pathology and Laboratory Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0034925PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338818PMC
September 2012

Modulation of microtubule dynamics by a TIR domain protein from the intracellular pathogen Brucella melitensis.

Biochem J 2011 Oct;439(1):79-83

Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA.

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http://dx.doi.org/10.1042/BJ20110577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513345PMC
October 2011

Biochemical and functional analysis of TIR domain containing protein from Brucella melitensis.

Biochem Biophys Res Commun 2010 Jun 13;397(1):59-63. Epub 2010 May 13.

Department of Pathobiological Sciences, University of Wisconsin-Madison, WI, USA.

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http://dx.doi.org/10.1016/j.bbrc.2010.05.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900483PMC
June 2010

Discordant Brucella melitensis antigens yield cognate CD8+ T cells in vivo.

Infect Immun 2010 Jan 2;78(1):168-76. Epub 2009 Nov 2.

Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA.

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http://dx.doi.org/10.1128/IAI.00994-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798188PMC
January 2010

Brucella regulators: self-control in a hostile environment.

Trends Microbiol 2009 Aug 5;17(8):371-7. Epub 2009 Aug 5.

University of Wisconsin, Department of Pathobiological Sciences, Madison, WI 53706, USA.

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http://dx.doi.org/10.1016/j.tim.2009.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487705PMC
August 2009

Brucella TIR Domain-containing Protein Mimics Properties of the Toll-like Receptor Adaptor Protein TIRAP.

J Biol Chem 2009 Apr 5;284(15):9892-8. Epub 2009 Feb 5.

Department of Pathobiological Sciences, University of Wisconsin, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1074/jbc.M805458200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665112PMC
April 2009

Evaluation of recombinant invasive, non-pathogenic Eschericia coli as a vaccine vector against the intracellular pathogen, Brucella.

J Immune Based Ther Vaccines 2009 Jan 6;7. Epub 2009 Jan 6.

Department of Pathobiological Sciences, University of Wisconsin-Madison, 1656 Linden Drive, Madison, WI 53706, USA.

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http://dx.doi.org/10.1186/1476-8518-7-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633335PMC
January 2009

DNA recognition properties of the cell-to-cell movement protein (MP) of soybean isolate of Mungbean yellow mosaic India virus (MYMIV-Sb).

Virus Res 2008 Feb 18;131(2):152-9. Epub 2007 Oct 18.

Department of Plant Biotechnology, School of Biotechnology, Madurai Kamaraj University, Madurai 625021, India.

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http://dx.doi.org/10.1016/j.virusres.2007.09.002DOI Listing
February 2008

Attenuated bioluminescent Brucella melitensis mutants GR019 (virB4), GR024 (galE), and GR026 (BMEI1090-BMEI1091) confer protection in mice.

Infect Immun 2006 May;74(5):2925-36

Department of Animal Health and Biomedical Sciences, University of Wisconsin-Madison, 1656 Linden Drive, Madison, WI 53706, USA.

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http://dx.doi.org/10.1128/IAI.74.5.2925-2936.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459743PMC
May 2006

Temporal analysis of pathogenic events in virulent and avirulent Brucella melitensis infections.

Cell Microbiol 2005 Oct;7(10):1459-73

Department of Animal Health and Biomedical Sciences, University of Wisconsin, Madison, 53706, USA.

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http://doi.wiley.com/10.1111/j.1462-5822.2005.00570.x
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http://dx.doi.org/10.1111/j.1462-5822.2005.00570.xDOI Listing
October 2005

Enhancement of antigen acquisition by dendritic cells and MHC class II-restricted epitope presentation to CD4+ T cells using VP22 DNA vaccine vectors that promote intercellular spreading following initial transfection.

J Leukoc Biol 2005 Aug 27;78(2):401-11. Epub 2005 Apr 27.

Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164-7040, USA.

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http://dx.doi.org/10.1189/jlb.1204722DOI Listing
August 2005

Nuclear and mitochondrial localization signals overlap within bovine herpesvirus 1 tegument protein VP22.

J Biol Chem 2005 Apr 10;280(16):16038-44. Epub 2005 Feb 10.

Department of Animal Health, University of Wisconsin, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1074/jbc.M500054200DOI Listing
April 2005

Nuclear and mitochondrial localization signals overlap within bovine herpesvirus 1 tegument protein VP22.

J Biol Chem 2005 Apr 10;280(16):16038-44. Epub 2005 Feb 10.

Department of Animal Health, University of Wisconsin, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1074/jbc.M500054200DOI Listing
April 2005

The role of integrase/recombinase xerD and monofunctional biosynthesis peptidoglycan transglycosylase genes in the pathogenicity of Brucella abortus infection in vitro and in vivo.

Microb Pathog 2004 Nov;37(5):241-51

Department of Animal Health and Biomedical Sciences, University of Wisconsin-Madison, 1656 Linden Drive, Madison, WI 53706, USA.

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http://dx.doi.org/10.1016/j.micpath.2004.07.004DOI Listing
November 2004

Denitrification genes regulate Brucella virulence in mice.

J Bacteriol 2004 Sep;186(18):6025-31

Department of Microbiology, Wing Hall, Cornell University, Ithaca, NY 14853-8101, USA.

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http://dx.doi.org/10.1128/JB.186.18.6025-6031.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC515144PMC
September 2004

Comparative whole-genome hybridization reveals genomic islands in Brucella species.

J Bacteriol 2004 Aug;186(15):5040-51

Department of Animal Health and Biomedical Sciences, University of Wisconsin, 1656 Linden Dr., Madison, WI 53706, USA.

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http://dx.doi.org/10.1128/JB.186.15.5040-5051.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC451633PMC
August 2004

Comparison of bovine leukemia virus (BLV) and CMV promoter-driven reporter gene expression in BLV-infected and non-infected cells.

Genet Vaccines Ther 2004 Aug 24;2(1):11. Epub 2004 Aug 24.

Department of Animal Health and Biomedical Sciences, University of Wisconsin-Madison, Madison, WI 53706-1581, USA.

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http://dx.doi.org/10.1186/1479-0556-2-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC516020PMC
August 2004

Comparative whole-genome hybridization reveals genomic islands in Brucella species.

J Bacteriol 2004 Aug;186(15):5040-51

Department of Animal Health and Biomedical Sciences, University of Wisconsin, 1656 Linden Dr., Madison, WI 53706, USA.

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http://dx.doi.org/10.1128/JB.186.15.5040-5051.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC451633PMC
August 2004

Molecular host-pathogen interaction in brucellosis: current understanding and future approaches to vaccine development for mice and humans.

Clin Microbiol Rev 2003 Jan;16(1):65-78

Laboratory of Cellular and Molecular Immunology, Department of Animal Health and Biomedical Sciences, University of Wisconsin, Madison, Wisconsin 53706, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC145300PMC
http://dx.doi.org/10.1128/cmr.16.1.65-78.2003DOI Listing
January 2003

Virulence criteria for Brucella abortus strains as determined by interferon regulatory factor 1-deficient mice.

Infect Immun 2002 Dec;70(12):7004-12

Laboratory of Cellular and Molecular Immunology, Department of Animal Health and Biomedical Sciences, University of Wisconsin, Madison 53706, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC132959PMC
http://dx.doi.org/10.1128/iai.70.12.7004-7012.2002DOI Listing
December 2002

Encephalomyocarditis and Mengo viruses productively infect murine T-lymphocyte cell lines but not fresh ex vivo derived T lymphocytes.

Viral Immunol 2002 ;15(1):155-63

Department of Animal Health and Biomedical Sciences, University of Wisconsin-Madison, 53706-1581, USA.

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http://dx.doi.org/10.1089/088282402317340305DOI Listing
October 2002

Molecular and immunological characterisation of recombinant Brucella abortus glyceraldehyde-3-phosphate-dehydrogenase, a T- and B-cell reactive protein that induces partial protection when co-administered with an interleukin-12-expressing plasmid in a DNA vaccine formulation.

J Med Microbiol 2002 Aug;51(8):661-671

Department of Biochemistry and Immunology and Institute for Investigation in Immunology - Millenium Institute, and *Department of General Biology, Federal University of Minas Gerais, Belo Horizonte, Brazil and †Department of Animal Health and Biomedical Sciences, University of Wisconsin, Madison, WI 53706, USA.

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http://dx.doi.org/10.1099/0022-1317-51-8-661DOI Listing
August 2002

Susceptibility of IFN regulatory factor-1 and IFN consensus sequence binding protein-deficient mice to brucellosis.

J Immunol 2002 Mar;168(5):2433-40

Laboratory of Cellular and Molecular Immunology, Department of Animal Health and Biomedical Sciences, University of Wisconsin, Madison, WI 53706, USA.

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http://dx.doi.org/10.4049/jimmunol.168.5.2433DOI Listing
March 2002

Mapping T and B lymphocyte epitopes of bovine herpesvirus-1 glycoprotein B.

J Gen Virol 1999 Oct;80 ( Pt 10):2699-2704

Department of Animal Health and Biomedical Sciences, University of Wisconsin-Madison, 1655 Linden Drive, Madison, WI 53706, USA1.

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http://dx.doi.org/10.1099/0022-1317-80-10-2699DOI Listing
October 1999