Garrett M Frampton

Garrett M Frampton

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Garrett M Frampton

Garrett M Frampton

Publications by authors named "Garrett M Frampton"

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Clinical and Immunological Implications of Frameshift Mutations in Lung Cancer.

J Thorac Oncol 2019 Oct 22;14(10):1807-1817. Epub 2019 Jun 22.

Leonard M. Miller School of Medicine, University of Miami, Miami, Florida; Memorial Sloan Kettering Cancer Center, New York, New York; Weill Cornell Medical College, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2019.06.016DOI Listing
October 2019

Microsatellite-Stable Tumors with High Mutational Burden Benefit from Immunotherapy.

Cancer Immunol Res 2019 Oct 12;7(10):1570-1573. Epub 2019 Aug 12.

University of California San Diego Moores Cancer Center, La Jolla, California.

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http://dx.doi.org/10.1158/2326-6066.CIR-19-0149DOI Listing
October 2019

Pan-Cancer Analysis of Loss-of-Function Alterations and Their Association with the Focal Tandem-Duplicator Phenotype.

Oncologist 2019 Jul 10. Epub 2019 Jul 10.

Johns Hopkins University School of Medicine and Bloomberg-Kimmel Institute for Cancer Immunotherapy, Baltimore, Maryland, USA

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http://dx.doi.org/10.1634/theoncologist.2019-0214DOI Listing
July 2019

PD-L1 expression and tumor mutational burden are independent biomarkers in most cancers.

JCI Insight 2019 Mar 21;4(6). Epub 2019 Mar 21.

Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1172/jci.insight.126908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482991PMC
March 2019

APOBEC-related mutagenesis and neo-peptide hydrophobicity: implications for response to immunotherapy.

Oncoimmunology 2019 24;8(3):1550341. Epub 2018 Dec 24.

Department of Medicine, Division of Hematology/Oncology, and Center for Personalized Cancer Therapy, University of California, Moores Cancer Center, La Jolla, CA, USA.

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http://dx.doi.org/10.1080/2162402X.2018.1550341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350681PMC
December 2018

Successful Treatment of HIV-Associated Kaposi Sarcoma with Immune Checkpoint Blockade.

Cancer Immunol Res 2018 10 7;6(10):1129-1135. Epub 2018 Sep 7.

Department of Medicine, Division of Hematology/Oncology, University of California San Diego, La Jolla, California.

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http://dx.doi.org/10.1158/2326-6066.CIR-18-0121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248326PMC
October 2018

GNAS, GNAQ, and GNA11 alterations in patients with diverse cancers.

Cancer 2018 10 11;124(20):4080-4089. Epub 2018 Sep 11.

Center for Personalized Cancer Therapy, University of California San Diego Moores Cancer Center, Louisiana Jolla, California.

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http://doi.wiley.com/10.1002/cncr.31724
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http://dx.doi.org/10.1002/cncr.31724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234097PMC
October 2018

Mutations and PD-1 Inhibitor Resistance in -Mutant Lung Adenocarcinoma.

Cancer Discov 2018 07 17;8(7):822-835. Epub 2018 May 17.

Department of Thoracic and Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/2159-8290.CD-18-0099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030433PMC
July 2018

Comprehensive Genomic Profiling of Renal Cell Carcinoma at Initial Diagnosis and Putative Local Recurrence.

Eur Urol Focus 2018 03 5;4(2):267-269. Epub 2016 Feb 5.

Department of Medical Oncology and Experimental Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.euf.2016.01.010DOI Listing
March 2018

Tumor Mutational Burden as an Independent Predictor of Response to Immunotherapy in Diverse Cancers.

Mol Cancer Ther 2017 11 23;16(11):2598-2608. Epub 2017 Aug 23.

Division of Hematology/Oncology, Department of Medicine, University of California San Diego, Moores Cancer Center, La Jolla, California.

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http://mct.aacrjournals.org/lookup/doi/10.1158/1535-7163.MCT
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http://dx.doi.org/10.1158/1535-7163.MCT-17-0386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670009PMC
November 2017

Severe nivolumab-induced pneumonitis preceding durable clinical remission in a patient with refractory, metastatic lung squamous cell cancer: a case report.

J Hematol Oncol 2017 02 28;10(1):64. Epub 2017 Feb 28.

Division of Hematology/Oncology, Department of Internal Medicine, University of California Davis School of Medicine, University of California Davis Comprehensive Cancer Center, 4501 X Street, Suite 3016, Sacramento, CA, 95817, USA.

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http://dx.doi.org/10.1186/s13045-017-0433-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331657PMC
February 2017

Characterization of 298 Patients with Lung Cancer Harboring MET Exon 14 Skipping Alterations.

J Thorac Oncol 2016 09 22;11(9):1493-502. Epub 2016 Jun 22.

Chao Family Comprehensive Cancer Center, University of California Irvine School of Medicine, Orange, California. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2016.06.004DOI Listing
September 2016

Comprehensive Genomic Profiling of Advanced Penile Carcinoma Suggests a High Frequency of Clinically Relevant Genomic Alterations.

Oncologist 2016 Jan 15;21(1):33-9. Epub 2015 Dec 15.

Foundation Medicine, Inc., Cambridge, Massachusetts, USA; Department of Medical Oncology, City of Hope Comprehensive Cancer Center, Duarte, California, USA; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, USA; Department of Pathology and Laboratory Medicine, Albany Medical College, Albany, New York, USA.

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http://www.foundationmedicine.com/wp-content/uploads/2015/12
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http://theoncologist.alphamedpress.org/cgi/doi/10.1634/theon
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http://dx.doi.org/10.1634/theoncologist.2015-0241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709208PMC
January 2016

MET 14 Deletion in Sarcomatoid Non-Small-Cell Lung Cancer Detected by Next-Generation Sequencing and Successfully Treated with a MET Inhibitor.

J Thorac Oncol 2015 Dec;10(12):e113-4

*Division of Hematology and Oncology, Linberger Comprehensive Cancer Center at the University of North Carolina, Chapel Hill, North Carolina; and †Research and Development, ‡Clinical Bioinformatics Operations, and §Clinical Development, Foundation Medicine Inc., Cambridge, Massachusetts.

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http://dx.doi.org/10.1097/JTO.0000000000000645DOI Listing
December 2015

Comparing two assays for clinical genomic profiling: the devil is in the data.

Onco Targets Ther 2015 24;8:2237-42. Epub 2015 Aug 24.

Foundation Medicine Inc., Cambridge, MA, USA.

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http://dx.doi.org/10.2147/OTT.S88908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556029PMC
September 2015

Concordance of genomic alterations between primary and recurrent breast cancer.

Mol Cancer Ther 2014 May 7;13(5):1382-9. Epub 2014 Mar 7.

Authors' Affiliations: Departments of Investigational Cancer Therapeutics, Surgical Oncology, Bioinformatics and Computational Biology, Pathology, Systems Biology, and Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas; Foundation Medicine, Cambridge, Massachusetts; Albany Medical College, Albany, New York; Fundacion para la Investigacion; Departments of Hematology-Oncology and Pathology, Hospital Clinico Universitario de Valencia; and INCLIVA Biomedical Research Institute, Valencia, Spain.

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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-13
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http://dx.doi.org/10.1158/1535-7163.MCT-13-0482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348062PMC
May 2014

CpG island structure and trithorax/polycomb chromatin domains in human cells.

Genomics 2012 Nov 20;100(5):320-6. Epub 2012 Jul 20.

Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1016/j.ygeno.2012.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483364PMC
November 2012

SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state.

Genes Dev 2009 Nov;23(21):2484-9

Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1101/gad.1837309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779743PMC
November 2009

Foxp3 occupancy and regulation of key target genes during T-cell stimulation.

Nature 2007 Feb 21;445(7130):931-5. Epub 2007 Jan 21.

Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/nature05478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008159PMC
February 2007

Reliability and reproducibility of gene expression measurements using amplified RNA from laser-microdissected primary breast tissue with oligonucleotide arrays.

J Mol Diagn 2005 Feb;7(1):57-64

Division of Graduate Medical Sciences, Boston University School of Medicine and Boston Medical Center, Boston, Massachusetts 02118, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1867505PMC
http://dx.doi.org/10.1016/S1525-1578(10)60009-8DOI Listing
February 2005

Pharmacogenomic identification of targets for adjuvant therapy with the topoisomerase poison camptothecin.

Cancer Res 2004 Mar;64(6):2096-104

Department of Genetics and Genomics, Boston University School of Medicine, Boston, Massachusetts, USA.

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http://cancerres.aacrjournals.org/content/canres/64/6/2096.f
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March 2004

Previously unidentified changes in renal cell carcinoma gene expression identified by parametric analysis of microarray data.

BMC Cancer 2003 Nov 27;3:31. Epub 2003 Nov 27.

Department of Genetics & Genomics, Boston University School of Medicine 715 Albany Street, E613 Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.1186/1471-2407-3-31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC317310PMC
November 2003