Garret M Hampton

Garret M Hampton

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Garret M Hampton

Garret M Hampton

Publications by authors named "Garret M Hampton"

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Activating Mutations in PIK3CB Confer Resistance to PI3K Inhibition and Define a Novel Oncogenic Role for p110β.

Cancer Res 2016 Mar 12;76(5):1193-203. Epub 2016 Jan 12.

Department of Oncology Biomarker Development, Genentech, Inc., South San Francisco, California.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-2201DOI Listing
March 2016

High-throughput detection of clinically relevant mutations in archived tumor samples by multiplexed PCR and next-generation sequencing.

Clin Cancer Res 2014 Apr 26;20(8):2080-91. Epub 2014 Feb 26.

Authors' Affiliations: Departments of Oncology Biomarker Development, Bioinformatics, Structural Biology, and Pathology, Genentech, Inc.; Fluidigm Inc., South San Francisco, California; and Expression Analysis, Durham, North Carolina.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-3114DOI Listing
April 2014

Discovery and development of DNA methylation-based biomarkers for lung cancer.

Epigenomics 2014 Feb;6(1):59-72

Department of Oncology Biomarker Development, Genentech Inc., South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.2217/epi.13.81DOI Listing
February 2014

Systematic analysis and validation of differential gene expression in ovarian serous adenocarcinomas and normal ovary.

J Cancer Res Clin Oncol 2013 Feb 23;139(2):347-55. Epub 2012 Oct 23.

Department of Gynecology and Obstetrics, University Medical Center RWTH, Pauwelsstrasse 30, 52074 Aachen, Germany.

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http://link.springer.com/10.1007/s00432-012-1334-8
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http://dx.doi.org/10.1007/s00432-012-1334-8DOI Listing
February 2013

Evaluation of circulating tumor cells and circulating tumor DNA in non-small cell lung cancer: association with clinical endpoints in a phase II clinical trial of pertuzumab and erlotinib.

Clin Cancer Res 2012 Apr 5;18(8):2391-401. Epub 2012 Apr 5.

Department of Oncology Biomarker Development and Oncology Clinical Development, Genentech, Inc, South San Francisco, California 94080, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-3148DOI Listing
April 2012

Cdc6 and cyclin E2 are PTEN-regulated genes associated with human prostate cancer metastasis.

Neoplasia 2009 Jan;11(1):66-76

Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA 22908, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606120PMC
http://dx.doi.org/10.1593/neo.81048DOI Listing
January 2009

A phosphoproteomic analysis of the ErbB2 receptor tyrosine kinase signaling pathways.

Biochemistry 2006 Dec 19;45(51):15529-40. Epub 2006 Dec 19.

Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1021/bi060971cDOI Listing
December 2006

Comprehensive analysis of HE4 expression in normal and malignant human tissues.

Mod Pathol 2006 Jun;19(6):847-53

Department of Pathology, Robert E. Fechner Laboratory of Surgical Pathology, University of Virginia Medical Center, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1038/modpathol.3800612DOI Listing
June 2006

A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase.

Proc Natl Acad Sci U S A 2006 Mar 28;103(10):3775-80. Epub 2006 Feb 28.

Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1073/pnas.0600040103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1383649PMC
March 2006

Mapping of candidate tumor suppressor genes on chromosome 12 in adenoid cystic carcinoma.

Lab Invest 2005 Sep;85(9):1076-85

Department of Pathology, University of Virginia Health System, Charlottesville, VA 22908-0708, USA.

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http://dx.doi.org/10.1038/labinvest.3700314DOI Listing
September 2005

Altered expression of TFF-1 and CES-2 in Barrett's Esophagus and associated adenocarcinomas.

Neoplasia 2005 Apr;7(4):407-16

Digestive Health Center of Excellence, Division of Gastroenterology and Hepatology, University of Virginia, Charlottesville, VA 22908, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1501154PMC
http://dx.doi.org/10.1593/neo.04715DOI Listing
April 2005

RNAi and HTS: exploring cancer by systematic loss-of-function.

Oncogene 2004 Nov;23(51):8392-400

Department of Chemistry, Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1038/sj.onc.1208217DOI Listing
November 2004

Profiling the evolution of human metastatic bladder cancer.

Cancer Res 2004 Nov;64(21):7813-21

Department of Molecular Physiology and Biological Physics, Division of Biostatistics, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-0826DOI Listing
November 2004

Overexpression of the 32-kilodalton dopamine and cyclic adenosine 3',5'-monophosphate-regulated phosphoprotein in common adenocarcinomas.

Cancer 2003 Oct;98(7):1547-51

Department of Medicine, Division of Gastroenterology, University of Virginia Health System, Charlottesville, Virginia 22908-0708, USA.

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http://dx.doi.org/10.1002/cncr.11654DOI Listing
October 2003

Exposing oncogenic dependencies for cancer drug target discovery and validation using RNAi.

Semin Cancer Biol 2003 Aug;13(4):293-300

The Genomics Institute of Novartis Research Institute Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121, USA.

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August 2003

Large-scale molecular and tissue microarray analysis of mesothelin expression in common human carcinomas.

Hum Pathol 2003 Jun;34(6):605-9

Department of Pathology, University of Virginia Health System, Charlottesville 22908, USA.

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http://dx.doi.org/10.1016/s0046-8177(03)00177-1DOI Listing
June 2003

An array of insights: application of DNA chip technology in the study of cell biology.

Trends Cell Biol 2003 Mar;13(3):151-6

The Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121, USA.

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March 2003

Classifying human cancer by analysis of gene expression.

Trends Mol Med 2003 Jan;9(1):5-10

Genomics Institute of the Novartis Research Foundation, 10 675 John Jay Hopkins Drive, San Diego, CA 92121, USA.

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January 2003

RhoGDI2 is an invasion and metastasis suppressor gene in human cancer.

Cancer Res 2002 Nov;62(22):6418-23

Department of Molecular Physiology and Biological Physics, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA.

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November 2002