Garret A FitzGerald

Front Immunol 2018 5;9:2565. Epub 2018 Nov 5.

Perelman School of Medicine, Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA, United States.

Clin Pharmacol Ther 2019 Sep 29;106(3):632-641. Epub 2019 Apr 29.

Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

J Pharmacol Exp Ther 2019 Sep 27;370(3):416-426. Epub 2019 Jun 27.

Department of Neuroscience, Imaging, and Clinical Sciences and Center for Research on Aging and Translational Medicine, "G. d'Annunzio" University School of Medicine, Chieti, Italy (A.Sa., A.B., A.C., M.D., S.T., P.G.-L., T.S., L.D.F., R.F., P.B., S.A., P.P.); Department of Systems Pharmacology and Translational Therapeutics and Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania (E.R., G.A.F.); Departments of General Pathology (V.A., A.Sg.) and Pharmacology (C.P.), Catholic University School of Medicine, Rome, Italy; Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Graduate School of the Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China (G.L., Y.G.); and Department of Pharmacology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China (Y.Y.)

Nat Commun 2019 Sep 11;10(1):4107. Epub 2019 Sep 11.

Institute of Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, PA, 19104, USA.

Sci Rep 2019 Sep 17;9(1):13477. Epub 2019 Sep 17.

Institute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, PA, USA.

Science 2019 08;365(6453):547-549

Divisions of Human Genetics and Immunobiology, Center for Chronobiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, 240 Albert Sabin Way, Cincinnati, OH 45229, USA.

J Pharmacol Exp Ther 2019 Jul 16;370(1):18-24. Epub 2019 Apr 16.

Advanced Institute for Medical Sciences, Dalian Medical University, Dalian, China (L.C., T.J.); School of Life Science and Biotechnology, Dalian University of Technology, Dalian, China (G.Y.); Institute for Translational Medicine and Therapeutics (L.C., G.Y., S.Y.T., G.A.F.) and Cardiovascular Institute (T.W., G.A.F.), University of Pennsylvania, Philadelphia, Pennsylvania; and State Key Laboratory of Medical Molecular Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (Q.W., M.W.)

J Clin Invest 2019 Jun 4;130:3594-3609. Epub 2019 Jun 4.

Department of Medicine.

JCI Insight 2019 Apr 11;5. Epub 2019 Apr 11.

Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Nat Commun 2019 04 23;10(1):1888. Epub 2019 Apr 23.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.

Sci Transl Med 2019 Apr;11(489)

Elazer R. Edelman is co-Chief Scientific Advisor of Science Translational Medicine. He is the Director and Edward J. Poitras Professor, Institute for Medical Engineering and Science at MIT, Cambridge, MA 02139, Professor of Medicine at Harvard Medical School, and Senior Attending Physician in the Division of Cardiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. Email:

J Pharmacol Exp Ther 2018 12 10;367(3):425-432. Epub 2018 Oct 10.

Department of Systems Pharmacology and Translational Therapeutics (W.-L.S., E.R., X.L., T.G., G.A.F.), Institute for Translational Medicine and Therapeutics (W.-L.S., E.R., X.L., T.G., G.R.G., G.A.F.), and Perelman School of Medicine and Department of Genetics (G.R.G.), University of Pennsylvania, Philadelphia, Pennsylvania

Arterioscler Thromb Vasc Biol 2018 12;38(12):2819-2826

The Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania (G.Y., S.T., X.L., G.A.F.).

Circulation 2018 11;138(21):2367-2378

Department of Systems Pharmacology and Translational Therapeutics and the Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, Philadelphia, PA (E.R., S.Y.T., D.M., S.D.R., H.M., X.L., N.F.L., A.M.W., G.A.F.).

Cell Rep 2018 11;25(6):1511-1524.e6

Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA, USA. Electronic address:

FASEB J 2018 10 20;32(10):5326-5337. Epub 2018 Apr 20.

Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada; and.

J Lipid Res 2018 10;59(10):2035

Front Pharmacol 2018 4;9:1093. Epub 2018 Oct 4.

SEMA4, a Mount Sinai Venture, Stamford, CT, United States.

Sci Rep 2018 08 14;8(1):12097. Epub 2018 Aug 14.

Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada.

Cell Rep 2018 07;24(4):809-814

Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-5127, USA. Electronic address:

J Immunol 2018 06 25;200(12):4004-4011. Epub 2018 Apr 25.

Department of Pharmacology and Toxicology, Boonshoft School of Medicine, Wright State University, Dayton, OH 45435;

Arterioscler Thromb Vasc Biol 2018 05 29;38(5):1115-1124. Epub 2018 Mar 29.

From the State Key Laboratory of Cardiovascular Disease (H.H., S.H., Q.W., C.X., H.C., L.Z., Z.X., J.M., M.W.)

J Exp Med 2018 04 30;215(4):1059-1068. Epub 2018 Jan 30.

Department of Neurology, Washington University School of Medicine, St. Louis, MO

Proc Natl Acad Sci U S A 2018 04 2;115(16):4170-4175. Epub 2018 Apr 2.

Division of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104;

J Lipid Res 2018 03 4;59(3):564-575. Epub 2018 Jan 4.

Institute for Translational Medicine and Therapeutics University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6160

Circ Res 2018 02;122(4):537-539

From the Institute for Translational Medicine and Therapeutics (T.G., G.A.F.) and Department of Surgery (A.N.), Perelman School of Medicine, University of Pennsylvania, Philadelphia.

J Lipid Res 2018 01 27;59(1):102-112. Epub 2017 Nov 27.

Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada

J Lipid Res 2018 01 27;59(1):89-101. Epub 2017 Nov 27.

Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada

EBioMedicine 2018 Jan 19;27:200-213. Epub 2017 Dec 19.

Department of Physiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada. Electronic address:

J Biol Rhythms 2017 Dec 1;32(6):505-515. Epub 2017 Sep 1.

Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Pennsylvania.

Sci Rep 2017 12 7;7(1):17141. Epub 2017 Dec 7.

Department of Systems Pharmacology and Translational Therapeutics, at the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.

Mol Metab 2017 11 19;6(11):1395-1406. Epub 2017 Aug 19.

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA. Electronic address:

Clin Pharmacol Ther 2017 Oct 17;102(4):611-622. Epub 2017 Aug 17.

Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Trends Genet 2017 10 24;33(10):760-769. Epub 2017 Aug 24.

Department of Systems Pharmacology and Translational Therapeutics, ​Perelman School of Medicine, University of Pennsylvania, 3400 Civic Center Boulevard, Smilow - 10th Floor, Room 122, Building 421, Philadelphia, PA 19104, USA. Electronic address:

J Biol Rhythms 2017 Oct 3;32(5):380-393. Epub 2017 Nov 3.

27 Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

Trends Pharmacol Sci 2017 08 23;38(8):733-748. Epub 2017 Jun 23.

Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

Science 2017 Mar 9;355(6329):1026-1027. Epub 2017 Mar 9.

Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Nat Methods 2017 02 12;14(2):135-139. Epub 2016 Dec 12.

Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Circulation 2017 01 13;135(2):113-115. Epub 2016 Nov 13.

From Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

JCI Insight 2016 Aug;1(12)

Department of Systems Pharmacology and Translational Therapeutics and Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Circulation 2016 Jul;134(4):328-38

From Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, Department of Systems Pharmacology and Translational Therapeutics (S.Y.T., J.M., L.T., S.-C.P., L.C., E.P., G.A.F.); Department of Animal Biology, School of Veterinary Medicine (S.Y.T., G.R.G., J.L.); and Department of Genetics, University of Pennsylvania, Philadelphia (J.M.).

Sci Transl Med 2016 06;8(343):343fs10

Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-5158, USA. Email:

Oncotarget 2016 May;7(22):32462-77

Department of Neuroscience, Imaging and Clinical Science, Section of Cardiovascular and Pharmacological Sciences, and CeSI-MeT, "G. d'Annunzio" University, School of Medicine, Chieti, Italy.

Cell Metab 2016 05;23(5):757-9

Institute for Translational Medicine and Therapeutics, 10-123 Smilow Center for Translational Research, Building 421, 3400 Civic Center Boulevard, Philadelphia, PA 19104-5158, USA. Electronic address:

JAMA 2016 Apr;315(16):1793-4

Institute for Translational Medicine and Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia.

Sci Transl Med 2016 Feb 3;8(324):324ra16. Epub 2016 Feb 3.

The Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Elife 2015 Dec 23;4:e08973. Epub 2015 Dec 23.

Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States.

Methods Enzymol 2015 26;552:211-28. Epub 2014 Dec 26.

Institute for Translational Medicine and Therapeutics, Smilow Center for Translational Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address:

JAMA 2015 Nov;314(17):1791-2

Institute for Translational Medicine and Therapeutics, Smilow Center for Translational Research, University of Pennsylvania Perelman School of Medicine, Philadelphia.

Science 2015 Oct;350(6258):282-3

Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

J Lipid Res 2015 Sep 15;56(9):1808-20. Epub 2015 Jul 15.

Institute for Translational Medicine and Therapeutics (ITMAT), Smilow Center for Translational Research, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104.

Pharmacogenet Genomics 2015 Aug;25(8):416-26

aDepartment of Systems Pharmacology and Translational Therapeutics, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Departments of bGenetics cBioengineering, Stanford University Medical Center, Stanford University, Stanford, California, USA.

Proc Natl Acad Sci U S A 2015 Aug 3;112(33):10479-84. Epub 2015 Aug 3.

Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, PA 19104;

Nat Genet 2015 Jun 27;47(6):569-76. Epub 2015 Apr 27.

1] Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA. [2] Department of Computer Science, Princeton University, Princeton, New Jersey, USA. [3] Simons Center for Data Analysis, Simons Foundation, New York, New York, USA.

Proc Natl Acad Sci U S A 2015 Jun 20;112(23):7231-6. Epub 2015 May 20.

School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland;

Science 2015 Jun;348(6240):1208-9

Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.

Sci Transl Med 2015 Apr;7(284):284fs15

Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-5158, USA.

Pharmacogenet Genomics 2015 Feb;25(2):96-106

aDepartment of Systems Pharmacology and Translational Therapeutics bInstitute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Departments of cGenetics dBioengineering, Stanford University, Stanford, California, USA.

Clin Ther 2014 Dec 23;36(12):2120-2121. Epub 2014 Oct 23.

Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

Proc Natl Acad Sci U S A 2014 Nov 10;111(47):16830-5. Epub 2014 Nov 10.

Institute for Translational Medicine and Therapeutics and

Science 2014 Nov;346(6212):921-2

Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Cell 2014 Oct;159(3):469-70

Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, PA 19104, USA. Electronic address:

Diabetes 2014 Sep 10;63(9):2911-23. Epub 2014 Apr 10.

Key Laboratory of Food Safety Research, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Graduate School of the Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China Key Laboratory of Food Safety Risk Assessment, Ministry of Health, Beijing, China

J Allergy Clin Immunol 2014 Sep 18;134(3):698-705.e5. Epub 2014 Jul 18.

Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tenn.

J Allergy Clin Immunol 2014 Aug 22;134(2):306-13. Epub 2014 Jan 22.

Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden; Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden.

Carcinogenesis 2014 Aug 3;35(8):1788-97. Epub 2014 Mar 3.

Institute for Translational Medicine and Therapeutics and Department of Pharmacology, University of Pennsylvania, Philadelphia, PA 19104, USA

Proc Natl Acad Sci U S A 2014 May 21;111(18):6828-33. Epub 2014 Apr 21.

The Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, The Department of Animal Biology, School of Veterinary Medicine, and The Department of Radiology, Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104.

Circulation 2014 Apr 11;129(17):1761-9. Epub 2014 Feb 11.

Institute for Translational Medicine and Therapeutics (S.Y.T., J.M., J.L., G.A.F.) and Perelman School of Medicine, Department of Animal Biology, School of Veterinary Medicine (L.T., E.P.), University of Pennsylvania, Philadelphia.

Am J Hum Genet 2014 Mar 20;94(3):349-60. Epub 2014 Feb 20.

Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

Circ Res 2014 Mar;114(7):1156-61

From the Departments of Medicine and Pharmacology, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

Am J Hum Genet 2014 Feb 23;94(2):198-208. Epub 2014 Jan 23.

Division of Transplantation, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA; Center for Applied Genomics, Abramson Research Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA. Electronic address:

J Clin Invest 2013 Dec 25;123(12):5389-400. Epub 2013 Nov 25.

Sci Transl Med 2013 Nov;5(212):212rv3

Institute for Translational Medicine and Therapeutics, Smilow Center for Translational Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

J Lipid Res 2013 Oct 15;54(10):2586-94. Epub 2013 Aug 15.

Institute for Translational Medicine and Therapeutics, Departments of Pharmacology and Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.

Clin Pharmacol Drug Dev 2013 Oct 25;2(4):379-86. Epub 2013 Jul 25.

Institute for Translational Medicine and Therapeutics (ITMAT), University of Pennsylvania, Philadelphia, PA, USA.

Circulation 2013 Sep;128(12):e191

Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

Handb Exp Pharmacol 2013 (217):243-60

Department of Neurology, Washington University School of Medicine, 7401 Byron Pl., Saint Louis, MO 63105, USA.

J Leukoc Biol 2013 Jul 26;94(1):77-88. Epub 2013 Apr 26.

Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, 1161 21st Ave., T-1218 MCN, Nashville, TN 37232-2650, USA.

Bio Protoc 2013 May;3(10)

Pharmacology Department, University of Pennsylvania, Philadelphia, USA.

J Invest Dermatol 2013 Apr 29;133(4):881-9. Epub 2012 Nov 29.

Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Hum Mol Genet 2013 Apr 8;22(8):1663-78. Epub 2013 Jan 8.

Division of Cardiovascular Medicine, University of Michigan Health System, Ann Arbor, MI, USA.

Clin Transl Sci 2013 Apr;6(2):85-7

University of Pittsburgh Clinical and Translational Science Institute, Pittsburgh, Pennsylvania, USA.

Circ Res 2013 02 18;112(3):432-40. Epub 2012 Dec 18.

The Institute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104-5158, USA.

Circ Res 2013 Feb;112(4):576-8

Circulation 2013 Jan 21;127(1):19-20. Epub 2012 Nov 21.

Circulation 2013 Jan 30;127(2):233-43. Epub 2012 Nov 30.

Institute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.

Circulation 2013 Jan 4;127(3):377-85. Epub 2012 Dec 4.

Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Circ Res 2013 Jan;112(1):174-94

UCD Conway Institute and Java Clinical Research, University College Dublin, Ireland.

Proc Natl Acad Sci U S A 2013 Jan 4;110(3):E183. Epub 2013 Jan 4.

Nat Med 2012 Dec 11;18(12):1768-77. Epub 2012 Nov 11.

Perelman School of Medicine, Institute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Bioconjug Chem 2012 Nov 1;23(11):2313-9. Epub 2012 Nov 1.

Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, PA 19104-6323, USA.

Arterioscler Thromb Vasc Biol 2012 Oct 9;32(10):2468-74. Epub 2012 Aug 9.

Cardiovascular Research Center, Hadassah Hebrew University Medical Center, Jerusalem 91120, Israel.

Sci Transl Med 2012 Oct;4(154):154cm10

Science 2012 Oct;338(6106):483-4

The Institute for Translational Medicine and Therapeutics, Perelman School of Medicine Translational Research Center, 10th Floor, 3400 Civic Center Boulevard, Philadelphia, PA 19104-5158, USA.

PLoS One 2012 10;7(5):e33518. Epub 2012 May 10.

Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America.

Circ Res 2012 Sep;111(8):965-6

Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Translational Research Center, Philadelphia, PA 19104-5158, USA.

Sci Transl Med 2012 May;4(132):132ra54

Institute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.

J Clin Invest 2012 Apr 12;122(4):1459-68. Epub 2012 Mar 12.

Institute for Translational Medicine and Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA.

Proc Natl Acad Sci U S A 2012 Apr 9;109(17):6727-32. Epub 2012 Apr 9.

Institute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, PA, 19104, USA.

Sci Transl Med 2012 Mar;4(126):126ra34

Department of Dermatology, Kligman Laboratories, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.