Gareth R John

Gareth R John

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Gareth R John

Gareth R John

Publications by authors named "Gareth R John"

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Karyopherin Alpha Proteins Regulate Oligodendrocyte Differentiation.

PLoS One 2017 20;12(1):e0170477. Epub 2017 Jan 20.

Friedman Brain Institute, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0170477PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5249183PMC
August 2017

Understanding How Exercise Promotes Cognitive Integrity in the Aging Brain.

PLoS Biol 2015 11;13(11):e1002300. Epub 2015 Nov 11.

Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pbio.1002300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641709PMC
May 2016

Functional Characterization of DNA Methylation in the Oligodendrocyte Lineage.

Cell Rep 2016 Apr 14;15(4):748-760. Epub 2016 Apr 14.

Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063656PMC
http://dx.doi.org/10.1016/j.celrep.2016.03.060DOI Listing
April 2016

Relapses in multiple sclerosis: Relationship to disability.

Mult Scler Relat Disord 2016 Mar 8;6:10-20. Epub 2015 Sep 8.

UCSF Regional Pediatric MS Center, Race to Erase MS, San Francisco, CA, United States.

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http://dx.doi.org/10.1016/j.msard.2015.09.002DOI Listing
March 2016

Update on biomarkers in neuromyelitis optica.

Neurol Neuroimmunol Neuroinflamm 2015 Aug 23;2(4):e134. Epub 2015 Jul 23.

Stanford University (E.M., M.H.H.), Stanford, CA; Johns Hopkins University (M.L.), Baltimore, MD; University of Oxford (P.J.W.), UK; Tohoku University (D.K.S.), Sendai, Japan; University of São Paulo (D.K.S.), Brazil; University of Colorado (J.L.B.), Denver; Mt. Sinai University (G.R.J.), New York, NY; Thomas Jefferson University (D.C.H.), Philadelphia, PA; IDIBAPS (A.S.), Barcelona, Spain; Montreal Neurological Institute and Hospital (A.B.-O.), McGill University, Montreal, Quebec, Canada; Research Institute and Hospital of National Cancer Center (H.J.K.), Goyang, Korea; KS Hegde Medical Academy (L.P.), Nitte University, Mangalore, India; Oxford University Hospital (M.I.L.), Oxford, UK; University of Southern Denmark (N.A.), Odense; Vejle Hospital (N.A.), Denmark; University Hospital (N.K.), Marrakech, Morocco; MS Center (R.H.), Erasmus MC University Medical Center, Rotterdam, the Netherlands; Service de Neurologie A (R.M.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Bron, France; Molecular Neuroimmunology (S.J.), Department of Neurology, University Hospital Heidelberg, Germany; Tandem Labs (J.M.), San Diego, CA; University of Michigan Medical School (T.J.S.), Ann Arbor, MI; and David Geffen School of Medicine (M.R.Y.), University of California, Los Angeles.

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http://dx.doi.org/10.1212/NXI.0000000000000134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516398PMC
August 2015

Astrocytic TYMP and VEGFA drive blood-brain barrier opening in inflammatory central nervous system lesions.

Brain 2015 Jun 23;138(Pt 6):1548-67. Epub 2015 Mar 23.

1 Corinne Goldsmith Dickinson Centre for MS, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA 2 Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA 3 Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA

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http://dx.doi.org/10.1093/brain/awv077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614128PMC
June 2015

Combinatorial actions of Tgfβ and Activin ligands promote oligodendrocyte development and CNS myelination.

Development 2014 Jun;141(12):2414-28

Neurology, Mount Sinai School of Medicine, New York, NY 10029, USA Corinne Goldsmith Dickinson Center for MS, Mount Sinai School of Medicine, New York, NY 10029, USA Friedman Brain Institute, Mount Sinai School of Medicine, New York, NY 10029, USA

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http://dev.biologists.org/cgi/doi/10.1242/dev.106492
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http://dx.doi.org/10.1242/dev.106492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050697PMC
June 2014

Accelerated repair of demyelinated CNS lesions in the absence of non-muscle myosin IIB.

Glia 2014 Apr 28;62(4):580-91. Epub 2014 Jan 28.

Department of Biological Sciences, Hunter College, New York, New York; The Graduate Center, Molecular Cellular and Developmental Biology, The City University of New York, New York.

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http://dx.doi.org/10.1002/glia.22627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135430PMC
April 2014

Investigation of astrocyte - oligodendrocyte interactions in human cultures.

Authors:
Gareth R John

Methods Mol Biol 2012 ;814:401-14

Department of Neurology, Mount Sinai School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1007/978-1-61779-452-0_27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299010PMC
March 2012

Promoting myelin repair and return of function in multiple sclerosis.

FEBS Lett 2011 Dec 18;585(23):3813-20. Epub 2011 Aug 18.

Corinne Goldsmith Dickinson Center for MS, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1016/j.febslet.2011.08.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223332PMC
December 2011

On the occurrence of hypomyelination in a transgenic mouse model: a consequence of the myelin basic protein promoter?

J Neuropathol Exp Neurol 2011 Dec;70(12):1138-50

Department of Pathology, Albert Einstein College of Medicine, Bronx, New York, USA.

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http://dx.doi.org/10.1097/NEN.0b013e31823b188bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774272PMC
December 2011

Targeting oligodendrocyte protection and remyelination in multiple sclerosis.

Mt Sinai J Med 2011 Mar-Apr;78(2):244-57

Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Mount Sinai School of Medicine, New York, NY, USA.

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http://dx.doi.org/10.1002/msj.20244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074606PMC
July 2011

Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination.

Proc Natl Acad Sci U S A 2009 Nov 23;106(45):19162-7. Epub 2009 Oct 23.

Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Department of Neurology, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1073/pnas.0902834106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776461PMC
November 2009

IL-11 regulates autoimmune demyelination.

J Immunol 2009 Oct 4;183(7):4229-40. Epub 2009 Sep 4.

Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Department of Neurology, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.4049/jimmunol.0900622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027139PMC
October 2009

VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown.

Proc Natl Acad Sci U S A 2009 Feb 27;106(6):1977-82. Epub 2009 Jan 27.

Corinne Goldsmith Dickinson Center for Multiple Sclerosis and Department of Neurology, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1073/pnas.0808698106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644149PMC
February 2009

Revisiting Notch in remyelination of multiple sclerosis lesions.

J Clin Invest 2009 Jan;119(1):10-3

Department of Pathology, Albert Einstein College of Medicine, New York, NY 10461, USA.

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http://dx.doi.org/10.1172/JCI37786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613471PMC
January 2009

Interleukin-11 potentiates oligodendrocyte survival and maturation, and myelin formation.

J Neurosci 2006 Nov;26(47):12174-85

Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Mount Sinai School of Medicine, New York, New York 10029, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.2289-06.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675431PMC
November 2006

IL-1beta regulates blood-brain barrier permeability via reactivation of the hypoxia-angiogenesis program.

J Immunol 2006 Oct;177(8):5574-84

Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.4049/jimmunol.177.8.5574DOI Listing
October 2006

CXC chemokine receptors on human oligodendrocytes: implications for multiple sclerosis.

Brain 2005 May 17;128(Pt 5):1003-15. Epub 2005 Mar 17.

Department of Pathology (Neuropathology), Albert Einstein College of Medicine, 1300 Morris Park Avenue, F-140, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1093/brain/awh479DOI Listing
May 2005

The cytokine IL-1beta activates IFN response factor 3 in human fetal astrocytes in culture.

J Immunol 2005 Mar;174(6):3719-26

Sue Golding Graduate Division, Department of Pathology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.4049/jimmunol.174.6.3719DOI Listing
March 2005

IL-1-regulated responses in astrocytes: relevance to injury and recovery.

Glia 2005 Jan;49(2):161-76

Department of Neurology, Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Mount Sinai School of Medicine, New York, New York 10641, USA.

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http://dx.doi.org/10.1002/glia.20109DOI Listing
January 2005

Interleukin-1beta induces a reactive astroglial phenotype via deactivation of the Rho GTPase-Rock axis.

J Neurosci 2004 Mar;24(11):2837-45

Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Department of Neurology, Mount Sinai School of Medicine, New York, New York 10029, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.4789-03.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6729504PMC
March 2004

Cytokines: powerful regulators of glial cell activation.

Neuroscientist 2003 Feb;9(1):10-22

Department of Pathology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1177/1073858402239587DOI Listing
February 2003

Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation.

Nat Med 2002 Oct 23;8(10):1115-21. Epub 2002 Sep 23.

Department of Pathology (Neuropathology), Albert Einstein College of Medicine, Bronx, New York, USA.

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http://dx.doi.org/10.1038/nm781DOI Listing
October 2002