Gareth J Morgan

Gareth J Morgan

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Gareth J Morgan

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Subclonal evolution in disease progression from MGUS/SMM to multiple myeloma is characterised by clonal stability.

Leukemia 2019 Feb 25;33(2):457-468. Epub 2018 Jul 25.

Myeloma Research Laboratory, Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, 5005, Australia.

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http://dx.doi.org/10.1038/s41375-018-0206-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365384PMC
February 2019

SAPIEN valve for percutaneous transcatheter pulmonary valve replacement without "pre-stenting": A multi-institutional experience.

Catheter Cardiovasc Interv 2019 Feb 23;93(2):324-329. Epub 2018 Oct 23.

Department of Pediatrics, Division of Cardiology, UCLA Mattel Children's Hospital, Los Angeles, California.

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http://dx.doi.org/10.1002/ccd.27932DOI Listing
February 2019

Variation in Anticoagulation Practices in the Congenital Cardiac Catheterization Lab: Results of a Multinational PICES Survey.

Pediatr Cardiol 2019 Jan 18;40(1):53-60. Epub 2018 Aug 18.

Division of Cardiology, The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

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http://dx.doi.org/10.1007/s00246-018-1960-2DOI Listing
January 2019

Pulmonary Artery Stenting.

Interv Cardiol Clin 2019 Jan 25;8(1):33-46. Epub 2018 Oct 25.

Department of Pediatric Cardiology, Children's Hospital of Colorado, University of Colorado School of Medicine, 13123 East 16th Avenue, Box 100, Aurora CO 80045, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S22117458183006
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http://dx.doi.org/10.1016/j.iccl.2018.08.005DOI Listing
January 2019

Role of domain interactions in the aggregation of full-length immunoglobulin light chains.

Proc Natl Acad Sci U S A 2019 Jan 31;116(3):854-863. Epub 2018 Dec 31.

Department of Molecular Genetics, The University of Toronto, Toronto, ON, Canada M5S 1A8;

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http://dx.doi.org/10.1073/pnas.1817538116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338840PMC
January 2019

Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.

Nat Commun 2019 01 10;10(1):213. Epub 2019 Jan 10.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.

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http://www.nature.com/articles/s41467-018-08107-8
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http://dx.doi.org/10.1038/s41467-018-08107-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328616PMC
January 2019

Reduced proximal aortic compliance and elevated wall shear stress after early repair of tetralogy of Fallot.

J Thorac Cardiovasc Surg 2018 Dec 21;156(6):2239-2249. Epub 2018 Sep 21.

Section of Congenital Heart Surgery, Heart Institute, Children's Hospital Colorado, University of Colorado Denver | Anschutz Medical Campus, Aurora, Colo.

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http://dx.doi.org/10.1016/j.jtcvs.2018.08.081DOI Listing
December 2018

Distinct promoter methylation profile reveals spatial epigenetic heterogeneity in 2 myeloma patients with multifocal extramedullary relapses.

Clin Epigenetics 2018 Dec 20;10(1):158. Epub 2018 Dec 20.

Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road, Pokfulam, Hong Kong.

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http://dx.doi.org/10.1186/s13148-018-0597-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302381PMC
December 2018

Close look at the Potts shunt flow hemodynamics in a patient with severe pulmonary hypertension: 4D-flow MRI evaluation.

J Magn Reson Imaging 2018 Nov 19. Epub 2018 Nov 19.

Section of Congenital Heart Surgery Heart Institute Children's Hospital Colorado, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, USA.

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http://dx.doi.org/10.1002/jmri.26554DOI Listing
November 2018

The genomic features associated with high-risk multiple myeloma.

Oncotarget 2018 Oct 26;9(84):35478-35479. Epub 2018 Oct 26.

Myeloma Institute, University of Arkansas for Medical Sciences, Little Rock, AR.

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http://dx.doi.org/10.18632/oncotarget.26269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231458PMC
October 2018

Impact of different coarctation therapies on aortic stiffness: phase-contrast MRI study.

Int J Cardiovasc Imaging 2018 Sep 17;34(9):1459-1469. Epub 2018 Apr 17.

Department of Radiology, Children's Hospital Colorado, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.

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http://dx.doi.org/10.1007/s10554-018-1357-6DOI Listing
September 2018

Three-Dimensional Echocardiographic Guidance of Right Heart Catheterization Decreases Radiation Exposure in Atrial Septal Defect Closures.

J Am Soc Echocardiogr 2018 Sep 27;31(9):1044-1049. Epub 2018 Jun 27.

Pediatric Cardiology, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado.

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http://dx.doi.org/10.1016/j.echo.2018.04.016DOI Listing
September 2018

Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.

Nat Commun 2018 09 13;9(1):3707. Epub 2018 Sep 13.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.

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http://www.nature.com/articles/s41467-018-04989-w
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http://dx.doi.org/10.1038/s41467-018-04989-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137048PMC
September 2018

Maintaining therapeutic progress in multiple myeloma by integrating genetic and biological advances into the clinic.

Expert Rev Hematol 2018 07 26;11(7):513-523. Epub 2018 Jun 26.

a Myeloma Institute , The University of Arkansas for Medical Sciences , Little Rock , AR , USA.

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http://dx.doi.org/10.1080/17474086.2018.1489718DOI Listing
July 2018

MAFb protein confers intrinsic resistance to proteasome inhibitors in multiple myeloma.

BMC Cancer 2018 Jul 6;18(1):724. Epub 2018 Jul 6.

Myeloma Institute, University of Arkansas for Medical Sciences, Winthrop P. Rockefeller Cancer Institute, 4301 West Markham St., Slot 776, Rm 914, Little Rock, AR, 72205, USA.

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http://dx.doi.org/10.1186/s12885-018-4602-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035431PMC
July 2018

Pulmonary Regurgitation- Is the Future Percutaneous or Surgical?

Authors:
Gareth J Morgan

Front Pediatr 2018 10;6:184. Epub 2018 Jul 10.

Congenital Interventional Cardiologist, Heart Institute, Children's Hospital of Colorado, University Colorado Hospital, Colorado University, Denver, CO, United States.

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http://dx.doi.org/10.3389/fped.2018.00184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048258PMC
July 2018

Stenting of the inter-atrial septum in infants and small children: Indications, techniques and outcomes.

Catheter Cardiovasc Interv 2018 Jun 11;91(7):1294-1300. Epub 2018 Jan 11.

Department of Paediatric Cardiology, Evelina London Children's Hospital, Guy's and St. Thomas' Hospital, London, United Kingdom.

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http://dx.doi.org/10.1002/ccd.27462DOI Listing
June 2018

HSF1 Is Essential for Myeloma Cell Survival and A Promising Therapeutic Target.

Clin Cancer Res 2018 May 1;24(10):2395-2407. Epub 2018 Feb 1.

Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, London, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-1594DOI Listing
May 2018

Optimus covered stent: Advanced covered stent technology for complex congenital heart disease.

Congenit Heart Dis 2018 May 21;13(3):458-462. Epub 2018 Feb 21.

Department of Pediatric Cardiology, Birmingham Children's Hospital, Birmingham, United Kingdom.

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http://dx.doi.org/10.1111/chd.12596DOI Listing
May 2018

Thymic PTH Increases After Thyroparathyroidectomy in C57BL/KaLwRij Mice.

Endocrinology 2018 04;159(4):1561-1569

Myeloma Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas.

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http://dx.doi.org/10.1210/en.2017-03083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839736PMC
April 2018

Large Calibre Self-Expanding Stents for Pulmonary Stenosis After the Arterial Switch, a Low-Risk Solution to a Low-Flow Situation.

Pediatr Cardiol 2018 Apr 22;39(4):824-828. Epub 2018 Feb 22.

Evelina London Childrens Hospital, Westminster Bridge Road, London, SE1 7EH, UK.

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http://link.springer.com/10.1007/s00246-018-1833-8
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http://dx.doi.org/10.1007/s00246-018-1833-8DOI Listing
April 2018

Evaluation of a modified Cheatham-Platinum stent for the treatment of aortic coarctation by finite element modelling.

JRSM Cardiovasc Dis 2018 Jan-Dec;7:2048004018773958. Epub 2018 Apr 27.

Department of Pediatrics, University of Texas Southwestern Medical Centre, Dallas, TX, USA.

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http://dx.doi.org/10.1177/2048004018773958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944143PMC
April 2018

Hybrid Strategy for High-Risk Neonates with Interrupted Aortic Arch: A Can Well Worth Kicking?

Int J Angiol 2018 Mar 19;27(1):50-53. Epub 2017 Apr 19.

Department of Paediatric Cardiology, Evelina Children's Hospital, London, United Kingdom.

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http://dx.doi.org/10.1055/s-0037-1602374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825225PMC
March 2018

Summary: FASEB Science Research Conference on Protein Aggregation in Health and Disease.

FASEB J 2018 03;32(3):1125-1129

Department of Molecular Medicine, The Scripps Research Institute, La Jolla, California, USA.

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http://dx.doi.org/10.1096/fj.201701266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236883PMC
March 2018

Measuring Flow Hemodynamic Indices and Oxygen Consumption in Children with Pulmonary Hypertension: A Comparison of Catheterization and Phase-Contrast MRI.

Pediatr Cardiol 2018 Feb 17;39(2):268-274. Epub 2017 Oct 17.

Division of Cardiology, Children's Hospital Colorado, Anschutz Medical Campus, 13123 E 16th Avenue, Aurora, CO, 80045-2560, USA.

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http://dx.doi.org/10.1007/s00246-017-1751-1DOI Listing
February 2018

Recombinant factor VIIa as a rescue therapy in severe haemoptysis in a patient with a Fontan circulation.

Cardiol Young 2018 Jan 11;28(1):144-146. Epub 2017 Sep 11.

2Adult Congenital Cardiology,St Thomas' Hospital, Guys and St Thomas' NHS foundation trust,London,United Kingdom.

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http://dx.doi.org/10.1017/S1047951117001007DOI Listing
January 2018

Translation efficiency is maintained at elevated temperature in .

J Biol Chem 2018 01 28;293(3):777-793. Epub 2017 Nov 28.

From the Departments of Chemistry and Molecular Medicine and

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http://dx.doi.org/10.1074/jbc.RA117.000284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777253PMC
January 2018

Integration of Genomics Into Treatment: Are We There Yet?

Am Soc Clin Oncol Educ Book 2017 ;37:569-574

From the Myeloma Institute, University of Arkansas for Medical Sciences, Little Rock, AR; Institute of Cancer Research, The Royal Marsden Hospital NHS Foundation Trust, London, United Kingdom.

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http://dx.doi.org/10.14694/EDBK_175166DOI Listing
December 2017

Incomplete Refolding of Antibody Light Chains to Non-Native, Protease-Sensitive Conformations Leads to Aggregation: A Mechanism of Amyloidogenesis in Patients?

Biochemistry 2017 Dec 4;56(50):6597-6614. Epub 2017 Dec 4.

Departments of Chemistry and Molecular Medicine, and ‡The Skaggs Institute for Chemical Biology, The Scripps Research Institute , La Jolla, California 92037, United States.

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http://dx.doi.org/10.1021/acs.biochem.7b00579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736400PMC
December 2017

Initial assessment of a novel delivery system (NuDEL™ ®) for the covered Cheatham-Platinum stent.

Cardiol Young 2017 Oct;27(8):1465-1469

1Departments of Paediatric and Adult Congenital Cardiology,Evelina London Children's Hospital,Guy's and St Thomas' NHS Foundation Trust,King's College London,London, United Kingdom.

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https://www.cambridge.org/core/product/identifier/S104795111
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http://dx.doi.org/10.1017/S1047951117000488DOI Listing
October 2017

Hyperhaploid karyotypes in multiple myeloma.

Oncotarget 2017 Oct 14;8(45):78259-78260. Epub 2017 Sep 14.

Jeffrey R. Sawyer: Department of Pathology, Myeloma Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

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http://dx.doi.org/10.18632/oncotarget.20875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667958PMC
October 2017

Active multiple myeloma suppresses and typically eliminates coexisting MGUS.

Br J Cancer 2017 Sep 20;117(6):835-839. Epub 2017 Jul 20.

Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham B15 2TT, UK.

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http://dx.doi.org/10.1038/bjc.2017.229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589985PMC
September 2017

Novel Three-Dimensional Image Fusion Software to Facilitate Guidance of Complex Cardiac Catheterization : 3D image fusion for interventions in CHD.

Pediatr Cardiol 2017 Aug 27;38(6):1133-1142. Epub 2017 May 27.

Department of Cardiology, Polish Mother's Memorial Hospital, Research Institute, Rzgowska Street 281/289, 93-338, Lodz, Poland.

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http://dx.doi.org/10.1007/s00246-017-1627-4DOI Listing
August 2017

Haematological cancer: Where are we now with the treatment of multiple myeloma?

Nat Rev Clin Oncol 2017 Aug 13;14(8):461-462. Epub 2017 Jun 13.

Myeloma Institute, University of Arkansas for Medical Sciences, 4301 W. Markham, Little Rock, Arkansas 72205, USA.

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http://dx.doi.org/10.1038/nrclinonc.2017.82DOI Listing
August 2017

Evolutionary biology of high-risk multiple myeloma.

Nat Rev Cancer 2017 08;17(9):543-556

The Myeloma Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA.

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http://dx.doi.org/10.1038/nrc.2017.63DOI Listing
August 2017

Comparison of self-expandable and balloon-expanding stents for hybrid ductal stenting in hypoplastic left heart complex.

Cardiol Young 2017 Jul;27(5):837-845

1Department of Congenital Heart Disease,Evelina London Children's Hospital,Guy's and St Thomas' NHS Foundation Trust,London,United Kingdom.

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http://dx.doi.org/10.1017/S1047951116001347DOI Listing
July 2017

Immunologic approaches for the treatment of multiple myeloma.

Cancer Treat Rev 2017 Apr 6;55:190-199. Epub 2017 Apr 6.

Myeloma Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

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http://dx.doi.org/10.1016/j.ctrv.2017.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604432PMC
April 2017

Fenestration closure with Amplatzer Duct Occluder II in patients after total cavo-pulmonary connection.

Arch Med Sci 2017 Mar 28;13(2):337-345. Epub 2016 Nov 28.

Department of Cardiology, Polish Mother's Memorial Hospital, Research Institute, Lodz, Poland.

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http://dx.doi.org/10.5114/aoms.2016.61836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332453PMC
March 2017

Echocardiographic Versus Angiographic Assessment of Patent Arterial Duct in Percutaneous Closure: Towards X-ray Free Duct Occlusion?

Pediatr Cardiol 2017 Feb 11;38(2):302-307. Epub 2017 Jan 11.

Department of Pediatric Cardiology, Evelina London Children's Hospital, Guys and St Thomas' NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1007/s00246-016-1513-5DOI Listing
February 2017

Early experience with the Occlutech PLD occluder for mitral paravalvar leak closure through a hybrid transapical approach.

EuroIntervention 2016 Dec 10;12(11):e1420-e1427. Epub 2016 Dec 10.

University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom.

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http://dx.doi.org/10.4244/EIJY15M12_07DOI Listing
December 2016

Monoclonal antibody therapy in multiple myeloma: where do we stand and where are we going?

Immunotherapy 2016 17;8(3):367-84. Epub 2016 Feb 17.

Myeloma Institute, University of Arkansas for Medical Sciences, 4301 West Markham, Little Rock, AR 72205, USA.

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http://dx.doi.org/10.2217/imt.15.118DOI Listing
December 2016

Initial experience with live three-dimensional image overlay for ductal stenting in hypoplastic left heart syndrome.

EuroIntervention 2016 Dec;12(12):1527-1533

Department of Cardiology, Polish Mother's Memorial Hospital, Research Institute, Lodz, Poland.

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http://dx.doi.org/10.4244/EIJ-D-15-00101DOI Listing
December 2016

Occlutech® muscular ventricular septal defect device: the first reported human use.

Authors:
Gareth J Morgan

Cardiol Young 2016 Oct 22;26(7):1448-51. Epub 2016 Jun 22.

Department of Congenital Cardiology,Guys and St Thomas' NHS Foundation Trust, Kings College London,London,United Kingdom.

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http://dx.doi.org/10.1017/S1047951116000949DOI Listing
October 2016

The Kinetic Stability of a Full-Length Antibody Light Chain Dimer Determines whether Endoproteolysis Can Release Amyloidogenic Variable Domains.

J Mol Biol 2016 10 26;428(21):4280-4297. Epub 2016 Aug 26.

Departments of Chemistry and Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA; The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065776PMC
http://dx.doi.org/10.1016/j.jmb.2016.08.021DOI Listing
October 2016

Use of an Edwards Sapien S3 valve to replace a dysfunctional mechanical mitral valve in an 11-year old boy: another small step for surgical and interventional collaboration.

Eur J Cardiothorac Surg 2016 Sep 18;50(3):577-9. Epub 2016 Mar 18.

Department of Congenital Cardiology, Guys and St Thomas' NHS Foundation Trust, London, UK

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http://dx.doi.org/10.1093/ejcts/ezw076DOI Listing
September 2016

Early European experience with the Venus P-valve®: filling the gap in percutaneous pulmonary valve implantation.

EuroIntervention 2016 Aug 5;12(5):e643-51. Epub 2016 Aug 5.

Department of Congenital Cardiology, Evelina London Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.

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http://dx.doi.org/10.4244/EIJV12I5A105DOI Listing
August 2016

The diagnosis and interventional management of pulmonary arteriovenous malformations.

EuroIntervention 2016 May;12 Suppl X:X24-X27

Department of Congenital Cardiology, Evelina London Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.

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http://dx.doi.org/10.4244/EIJV12SXA5DOI Listing
May 2016

Live 3D image overlay for arterial duct closure with Amplatzer Duct Occluder II additional size.

Cardiol Young 2016 Mar 11;26(3):605-8. Epub 2015 Sep 11.

1Department of Cardiology,Research Institute,Polish Mother's Memorial Hospital,Lodz,Poland.

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http://dx.doi.org/10.1017/S1047951115001638DOI Listing
March 2016

Left Ventricular Myocardial and Hemodynamic Response to Exercise in Young Patients after Endovascular Stenting for Aortic Coarctation.

J Am Soc Echocardiogr 2016 Mar 30;29(3):237-46. Epub 2015 Dec 30.

Department of Pediatrics, Division of Cardiology, The Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto School of Medicine, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.echo.2015.11.017DOI Listing
March 2016

Hybrid Procedure for Neonates With Hypoplastic Left Heart Syndrome at High-Risk for Norwood: Midterm Outcomes.

Ann Thorac Surg 2015 Dec 1;100(6):2286-90; discussion 2291-2. Epub 2015 Oct 1.

Department of Cardiology and Cardiac Surgery, Evelina London Children's Hospital, Guy's & St. Thomas' NHS Foundation Trust, London, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S00034975150113
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http://dx.doi.org/10.1016/j.athoracsur.2015.06.098DOI Listing
December 2015

Mutational Spectrum, Copy Number Changes, and Outcome: Results of a Sequencing Study of Patients With Newly Diagnosed Myeloma.

J Clin Oncol 2015 Nov 17;33(33):3911-20. Epub 2015 Aug 17.

Brian A. Walker, Eileen M. Boyle, Christopher P. Wardell, Alex Murison, Dil B. Begum, Nasrin M. Dahir, Paula Z. Proszek, David C. Johnson, Martin F. Kaiser, Lorenzo Melchor, Lauren I. Aronson, Charlotte Pawlyn, Fabio Mirabella, John R. Jones, Annamaria Brioli, Faith E. Davies, and Gareth J. Morgan, The Institute of Cancer Research, London; Matthew Scales, The Institute of Cancer Research, Surrey; David A. Cairns, Walter M. Gregory, and Ana Quartilho, University of Leeds; Gordon Cook, St James's University Hospital, Leeds; Mark T. Drayson, University of Birmingham, Birmingham; Nigel Russell, Nottingham University Hospital, Nottingham; Graham H. Jackson, Newcastle University, Newcastle upon Tyne, United Kingdom; Aneta Mikulasova, Masaryk University, Brno, Czech Republic; and Xavier Leleu, Hôpital C. Huriez, Centre Hospitalier Régional Universitaire de Lille, Lille, France.

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http://ascopubs.org/doi/10.1200/JCO.2014.59.1503
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http://dx.doi.org/10.1200/JCO.2014.59.1503DOI Listing
November 2015