Gareth A Wilson

Gareth A Wilson

UNVERIFIED PROFILE

Are you Gareth A Wilson?   Register this Author

Register author
Gareth A Wilson

Gareth A Wilson

Publications by authors named "Gareth A Wilson"

Are you Gareth A Wilson?   Register this Author

32Publications

1044Reads

23Profile Views

Computational Methods for Analysis of Tumor Clonality and Evolutionary History.

Methods Mol Biol 2019 ;1878:217-226

Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-8868-6_13DOI Listing
May 2019

Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal.

Cell 2018 04 12;173(3):595-610.e11. Epub 2018 Apr 12.

Translational Cancer Therapeutics Laboratory, the Francis Crick Institute, London NW1 1AT, UK; Cancer Research UK Lung Cancer Centre of Excellence London, University College London Cancer Institute, London WC1E 6DD, UK; Department of Medical Oncology, University College London Hospitals, London NW1 2BU, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2018.03.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938372PMC
April 2018

Corrigendum: Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.

Authors:
Christopher Abbosh Nicolai J Birkbak Gareth A Wilson Mariam Jamal-Hanjani Tudor Constantin Raheleh Salari John Le Quesne David A Moore Selvaraju Veeriah Rachel Rosenthal Teresa Marafioti Eser Kirkizlar Thomas B K Watkins Nicholas McGranahan Sophia Ward Luke Martinson Joan Riley Francesco Fraioli Maise Al Bakir Eva Grönroos Francisco Zambrana Raymondo Endozo Wenya Linda Bi Fiona M Fennessy Nicole Sponer Diana Johnson Joanne Laycock Seema Shafi Justyna Czyzewska-Khan Andrew Rowan Tim Chambers Nik Matthews Samra Turajlic Crispin Hiley Siow Ming Lee Martin D Forster Tanya Ahmad Mary Falzon Elaine Borg David Lawrence Martin Hayward Shyam Kolvekar Nikolaos Panagiotopoulos Sam M Janes Ricky Thakrar Asia Ahmed Fiona Blackhall Yvonne Summers Dina Hafez Ashwini Naik Apratim Ganguly Stephanie Kareht Rajesh Shah Leena Joseph Anne Marie Quinn Phil A Crosbie Babu Naidu Gary Middleton Gerald Langman Simon Trotter Marianne Nicolson Hardy Remmen Keith Kerr Mahendran Chetty Lesley Gomersall Dean A Fennell Apostolos Nakas Sridhar Rathinam Girija Anand Sajid Khan Peter Russell Veni Ezhil Babikir Ismail Melanie Irvin-Sellers Vineet Prakash Jason F Lester Malgorzata Kornaszewska Richard Attanoos Haydn Adams Helen Davies Dahmane Oukrif Ayse U Akarca John A Hartley Helen L Lowe Sara Lock Natasha Iles Harriet Bell Yenting Ngai Greg Elgar Zoltan Szallasi Roland F Schwarz Javier Herrero Aengus Stewart Sergio A Quezada Karl S Peggs Peter Van Loo Caroline Dive C Jimmy Lin Matthew Rabinowitz Hugo J W L Aerts Allan Hackshaw Jacqui A Shaw Bernhard G Zimmermann Charles Swanton

Nature 2018 02 20;554(7691):264. Epub 2017 Dec 20.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature25161DOI Listing
February 2018

Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution.

Cell 2017 Nov 26;171(6):1259-1271.e11. Epub 2017 Oct 26.

Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London WC1E 6BT, UK; Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, 1 Midland Rd, London NW1 1AT, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2017.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720478PMC
November 2017

Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection.

BMC Bioinformatics 2017 Jul 25;18(1):354. Epub 2017 Jul 25.

UCL Cancer Institute, University College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12859-017-1753-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526259PMC
July 2017

Tracking the Evolution of Non-Small-Cell Lung Cancer.

N Engl J Med 2017 06 26;376(22):2109-2121. Epub 2017 Apr 26.

From the Cancer Research UK Lung Cancer Centre of Excellence (M.J.-H., G.A.W., N. McGranahan, N.J.B., S.V., S.S., D.H.J., R.R., S.-M.L., M.D.F., C.A., S.M.J., C.D., C.S.), London and Manchester, Good Clinical Laboratory Practice Facility, University College London (UCL) Experimental Cancer Medicine Centre (H.L.L., J.A.H.), Bill Lyons Informatics Centre (J.H.), and Cancer Immunology Unit (S.A.Q.), UCL Cancer Institute, the Translational Cancer Therapeutics Laboratory (G.A.W., N. McGranahan, N.J.B., T.B.K.W., A.R., T.C., S. Turajlic, H.X., C.T.H., C.S.), Department of Bioinformatics and Biostatistics (R.M., M.S., S.H., M.E., A.S.), Advanced Sequencing Facility (N. Matthews), and Cancer Genomics Laboratory (S.D., P.V.L.), Francis Crick Institute, the Renal and Skin Units, Royal Marsden Hospital (S. Turajlic), the Departments of Medical Oncology (M.J.-H., S.-M.L., M.D.F., T.A., C.A., C.S.), Pathology (M.F., E.B., T.M.), Cardiothoracic Surgery (D.L., M.H., S. Kolvekar, N.P.), Respiratory Medicine (S.M.J., R.T.), and Radiology (A.A.), UCL Hospitals, Lungs for Living, UCL Respiratory, UCL (S.M.J.), the Department of Radiotherapy, North Middlesex University Hospital (G.A.), the Department of Respiratory Medicine, Royal Free Hospital (S. Khan), and UCL Cancer Research UK and Cancer Trials Centre (N.I., H.B., Y.N., A.H.), London, Cancer Studies, University of Leicester (D.A.M., D.A.F., J.A.S., J.L.Q.), the Department of Thoracic Surgery, Glenfield Hospital (A.N., S.R.), and the Medical Research Center Toxicology Unit (J.L.Q.), Leicester, the Institute of Cancer Studies, University of Manchester (F.B.), the Christie Hospital (F.B., Y.S.), the Departments of Cardiothoracic Surgery (R.S.) and Pathology (L.J., A.M.Q.) and the North West Lung Centre (P.A.C.), University Hospital of South Manchester, and Cancer Research UK Manchester Institute (C.D.), Manchester, the Departments of Thoracic Surgery (B.N.) and Cellular Pathology (G.L., S. Trotter), Birmingham Heartlands Hospital, Molecular Pathology Diagnostic Services, Queen Elizabeth Hospital (P.T., B.O.), and Institute of Immunology and Immunotherapy, University of Birmingham (G.M.), Birmingham, the Departments of Medical Oncology (M.N.), Cardiothoracic Surgery (H.R.), Pathology (K.K.), Respiratory Medicine (M.C.), and Radiology (L.G.), Aberdeen University Medical School and Aberdeen Royal Infirmary, Aberdeen, the Department of Respiratory Medicine, Barnet and Chase Farm Hospitals, Barnet (S. Khan), the Department of Respiratory Medicine, Princess Alexandra Hospital, Harlow (P.R.), the Department of Clinical Oncology, St. Luke's Cancer Centre, Guildford (V.E.), the Departments of Pathology (B.I.), Respiratory Medicine (M.I.-S.), and Radiology (V.P.), Ashford and St. Peters' Hospitals, Surrey, the Department of Clinical Oncology, Velindre Hospital (J.F.L.), the Departments of Radiology (H.A.) and Respiratory Medicine (H.D.), University Hospital Llandough, the Departments of Pathology (R.A.) and Cardiothoracic Surgery (M.K.), University Hospital of Wales, and Cardiff University (R.A.), Cardiff, and Wellcome Trust Sanger Institute, Hinxton, and Big Data Institute, University of Oxford, Oxford (S.D.) - all in the United Kingdom; the Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby (Z.S.); the Computational Health Informatics Program, Boston Children's Hospital and Harvard Medical School, Boston (Z.S.); MTA-SE-NAP, Brain Metastasis Research Group, 2nd Department of Pathology, Semmelweis University, Budapest, Hungary (Z.S.); Berlin Institute for Medical Systems Biology, Max Delbrueck Center for Molecular Medicine, Berlin (R.F.S.); and the Department of Human Genetics, University of Leuven, Leuven, Belgium (P.V.L.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa1616288DOI Listing
June 2017

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.

Authors:
Christopher Abbosh Nicolai J Birkbak Gareth A Wilson Mariam Jamal-Hanjani Tudor Constantin Raheleh Salari John Le Quesne David A Moore Selvaraju Veeriah Rachel Rosenthal Teresa Marafioti Eser Kirkizlar Thomas B K Watkins Nicholas McGranahan Sophia Ward Luke Martinson Joan Riley Francesco Fraioli Maise Al Bakir Eva Grönroos Francisco Zambrana Raymondo Endozo Wenya Linda Bi Fiona M Fennessy Nicole Sponer Diana Johnson Joanne Laycock Seema Shafi Justyna Czyzewska-Khan Andrew Rowan Tim Chambers Nik Matthews Samra Turajlic Crispin Hiley Siow Ming Lee Martin D Forster Tanya Ahmad Mary Falzon Elaine Borg David Lawrence Martin Hayward Shyam Kolvekar Nikolaos Panagiotopoulos Sam M Janes Ricky Thakrar Asia Ahmed Fiona Blackhall Yvonne Summers Dina Hafez Ashwini Naik Apratim Ganguly Stephanie Kareht Rajesh Shah Leena Joseph Anne Marie Quinn Phil A Crosbie Babu Naidu Gary Middleton Gerald Langman Simon Trotter Marianne Nicolson Hardy Remmen Keith Kerr Mahendran Chetty Lesley Gomersall Dean A Fennell Apostolos Nakas Sridhar Rathinam Girija Anand Sajid Khan Peter Russell Veni Ezhil Babikir Ismail Melanie Irvin-Sellers Vineet Prakash Jason F Lester Malgorzata Kornaszewska Richard Attanoos Haydn Adams Helen Davies Dahmane Oukrif Ayse U Akarca John A Hartley Helen L Lowe Sara Lock Natasha Iles Harriet Bell Yenting Ngai Greg Elgar Zoltan Szallasi Roland F Schwarz Javier Herrero Aengus Stewart Sergio A Quezada Karl S Peggs Peter Van Loo Caroline Dive C Jimmy Lin Matthew Rabinowitz Hugo J W L Aerts Allan Hackshaw Jacqui A Shaw Bernhard G Zimmermann Charles Swanton

Nature 2017 04;545(7655):446-451

Cancer Research UK Lung Cancer Centre of Excellence London and Manchester, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London WC1E 6DD, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature22364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812436PMC
April 2017

Human-specific epigenetic variation in the immunological Leukotriene B4 Receptor (LTB4R/BLT1) implicated in common inflammatory diseases.

Genome Med 2014 5;6(3):19. Epub 2014 Mar 5.

Medical Genomics, UCL Cancer Institute, University College London, London, UK ; Current address: Department of Twin Research & Genetic Epidemiology, St Thomas' Hospital, King's College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/gm536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062055PMC
August 2014

Human-specific CpG 'beacons' identify human-specific prefrontal cortex H3K4me3 chromatin peaks.

Epigenomics 2014 Feb;6(1):21-31

Medical Genomics, UCL Cancer Institute, University College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/epi.13.74DOI Listing
February 2014

DNA methylation analysis of murine hematopoietic side population cells during aging.

Epigenetics 2013 Oct 15;8(10):1114-22. Epub 2013 Aug 15.

UCL Institute of Healthy Ageing; University College London; London, UK; These senior authors contributed equally to this work.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/epi.26017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891692PMC
October 2013

Integrated virus-host methylome analysis in head and neck squamous cell carcinoma.

Epigenetics 2013 Sep 18;8(9):953-61. Epub 2013 Jul 18.

Medical Genomics; UCL Cancer Institute; University College London; London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/epi.25614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883772PMC
September 2013

A functional methylome map of ulcerative colitis.

Genome Res 2012 Nov 23;22(11):2130-7. Epub 2012 Jul 23.

Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, 24105 Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.138347.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483542PMC
November 2012

Human-specific CpG "beacons" identify loci associated with human-specific traits and disease.

Epigenetics 2012 Oct 11;7(10):1188-99. Epub 2012 Sep 11.

Medical Genomics, UCL Cancer Institute, University College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/epi.22127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469460PMC
October 2012

Methylome analysis using MeDIP-seq with low DNA concentrations.

Nat Protoc 2012 Mar 8;7(4):617-36. Epub 2012 Mar 8.

University College London (UCL) Cancer Institute, University College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nprot.2012.012DOI Listing
March 2012

Databases and software for the comparison of prokaryotic genomes.

Microbiology 2005 Jul;151(Pt 7):2125-32

Oxford Centre for Ecology and Hydrology, Mansfield Road, Oxford OX1 3SR, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1099/mic.0.28006-0DOI Listing
July 2005