Ganesh S Moorthy

Ganesh S Moorthy

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Ganesh S Moorthy

Ganesh S Moorthy

Publications by authors named "Ganesh S Moorthy"

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14Publications

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An improved ultra-high-performance liquid chromatography-tandem mass spectrometric method for the quantitation of dexmedetomidine in small volume of pediatric plasma.

Biomed Chromatogr 2019 Jun 7;33(6):e4487. Epub 2019 Feb 7.

Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1002/bmc.4487DOI Listing
June 2019

Development and validation of a volumetric absorptive microsampling assay for analysis of voriconazole and voriconazole N-oxide in human whole blood.

J Chromatogr B Analyt Technol Biomed Life Sci 2019 Jan 8;1105:67-75. Epub 2018 Dec 8.

Center for Clinical Pharmacology, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA 19104, United States of America; Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA 19104, United States of America.

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https://linkinghub.elsevier.com/retrieve/pii/S15700232183135
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http://dx.doi.org/10.1016/j.jchromb.2018.12.007DOI Listing
January 2019

Enhanced Intratumoral Delivery of SN38 as a Tocopherol Oxyacetate Prodrug Using Nanoparticles in a Neuroblastoma Xenograft Model.

Clin Cancer Res 2018 06 7;24(11):2585-2593. Epub 2018 Mar 7.

Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-3811DOI Listing
June 2018

Ketamine and norketamine stability in whole blood at ambient and 4°C conditions.

Biomed Chromatogr 2018 Mar 9;32(3). Epub 2017 Nov 9.

Center for Clinical Pharmacology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1002/bmc.4104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801204PMC
March 2018

Development and validation of a sensitive assay for analysis of midazolam, free and conjugated 1-hydroxymidazolam and 4-hydroxymidazolam in pediatric plasma: Application to Pediatric Pharmacokinetic Study.

J Chromatogr B Analyt Technol Biomed Life Sci 2017 Nov 28;1067:1-9. Epub 2017 Sep 28.

Center for Clinical Pharmacology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States; Department of Anesthesiology and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States.

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http://dx.doi.org/10.1016/j.jchromb.2017.09.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662017PMC
November 2017

Brief Report: CYP2B6 516G>T Minor Allele Protective of Late Virologic Failure in Efavirenz-Treated HIV-Infected Patients in Botswana.

J Acquir Immune Defic Syndr 2017 08;75(4):488-491

*Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA; †Department of Epidemiology and Biostatistics, Dornsife School of Public Health, Drexel University, Philadelphia, PA; ‡Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA; §Metrum Research Group, Tariffville, CT; ‖Botswana-UPenn Partnership, University of Botswana, Gaborone, Botswana; ¶Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA; #Division of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, PA; **Faculty of Medicine, University of Botswana, Gaborone, Botswana; ††Office of the Chancellor, Rutgers Biomedical and Health Sciences, Rutgers University, Newark, NJ; and ‡‡Department of Medicine (Infectious Diseases), University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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http://Insights.ovid.com/crossref?an=00126334-201708010-0001
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http://dx.doi.org/10.1097/QAI.0000000000001442DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524513PMC
August 2017

Population pharmacokinetics of midazolam and its metabolites in overweight and obese adolescents.

Br J Clin Pharmacol 2015 Nov 10;80(5):1185-96. Epub 2015 Sep 10.

Division of Clinical Pharmacology, Children's National Medical Center, Washington DC, USA.

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http://dx.doi.org/10.1111/bcp.12693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631191PMC
November 2015

A liquid chromatography/tandem mass spectrometry method for determination of obatoclax in human plasma.

J Chromatogr B Analyt Technol Biomed Life Sci 2014 Nov 16;971:30-4. Epub 2014 Sep 16.

Division of Clinical Pharmacology and Therapeutics, The Children's Hospital of Philadelphia, United States of America; Division of Oncology, The Children's Hospital of Philadelphia, United States of America.

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http://dx.doi.org/10.1016/j.jchromb.2014.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252240PMC
November 2014

A sensitive and selective liquid chromatography/tandem mass spectrometry method for quantitative analysis of efavirenz in human plasma.

PLoS One 2013 5;8(6):e63305. Epub 2013 Jun 5.

Division of Clinical Pharmacology & Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0063305PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673986PMC
January 2014

Comparative preclinical drug metabolism and pharmacokinetic evaluation of novel 4-aminoquinoline anti-malarials.

J Pharm Sci 2009 Jan;98(1):362-77

Drug Metabolism and Pharmacokinetics, GlaxoSmithKline Drug Discovery, 1250 South Collegeville Rd, Collegeville, Pennsylvania 19426, USA.

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http://dx.doi.org/10.1002/jps.21469DOI Listing
January 2009

Preclinical drug metabolism and pharmacokinetic evaluation of GW844520, a novel anti-malarial mitochondrial electron transport inhibitor.

J Pharm Sci 2006 Dec;95(12):2657-72

Drug Metabolism and Pharmacokinetics, Microbial, Musculoskeletal and Proliferative Diseases, Center of Excellence for Drug Discovery, GlaxoSmithKline R&D, 1250 South Collegeville Rd, Collegeville, PA 19426, USA.

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http://dx.doi.org/10.1002/jps.20681DOI Listing
December 2006