Galen Hostetter

Galen Hostetter

UNVERIFIED PROFILE

Are you Galen Hostetter?   Register this Author

Register author
Galen Hostetter

Galen Hostetter

Publications by authors named "Galen Hostetter"

Are you Galen Hostetter?   Register this Author

61Publications

1603Reads

7Profile Views

Notch3 promotes prostate cancer-induced bone lesion development via MMP-3.

Oncogene 2020 Jan 29;39(1):204-218. Epub 2019 Aug 29.

Program for Skeletal Disease and Tumor Microenvironment, Center for Cancer and Cell Biology, Grand Rapids, MI, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41388-019-0977-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938550PMC
January 2020

Characterization of farnesyl diphosphate farnesyl transferase 1 (FDFT1) expression in cancer.

Per Med 2019 01 23;16(1):51-65. Epub 2018 Nov 23.

Translational Genomics Research Institute (TGen), Phoenix, AZ 85004, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/pme-2016-0058DOI Listing
January 2019

KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism.

Cancer Cell 2018 11;34(5):807-822.e7

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:

View Article

Download full-text PDF

Source
https://www.researchgate.net/publication/325458004_KRAS_Supp
Web Search
http://scholar.google.fi/citations?user=_42T_HMAAAAJ&hl=en
Web Search
https://www.journals.elsevier.com/cancer-cell/recent-article
Web Search
https://linkinghub.elsevier.com/retrieve/pii/S15356108183046
Publisher Site
http://dx.doi.org/10.1016/j.ccell.2018.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321749PMC
November 2018

Nuclear PTEN Localization Contributes to DNA Damage Response in Endometrial Adenocarcinoma and Could Have a Diagnostic Benefit for Therapeutic Management of the Disease.

Mol Cancer Ther 2018 09 13;17(9):1995-2003. Epub 2018 Jun 13.

Department of Obstetrics, Gynecology and Reproductive Biology, College of Human Medicine, Michigan State University, Grand Rapids, Michigan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1535-7163.MCT-17-1255DOI Listing
September 2018

Volume Retention, Metabolism, and Cellular Composition of Human Fat Xenografts.

Plast Reconstr Surg Glob Open 2018 Aug 6;6(8):e1869. Epub 2018 Aug 6.

Michigan State University College of Human Medicine, Grand Rapids, Mich.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/GOX.0000000000001869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181496PMC
August 2018

Inhibition of ROCK1 kinase modulates both tumor cells and stromal fibroblasts in pancreatic cancer.

PLoS One 2017 25;12(8):e0183871. Epub 2017 Aug 25.

Molecular Medicine Division, The Translational Genomics Research Institute, Phoenix, Arizona, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0183871PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571985PMC
October 2017

Concurrent Hepsin overexpression and adenomatous polyposis coli deletion causes invasive prostate carcinoma in mice.

Prostate 2015 Oct 2;75(14):1579-85. Epub 2015 Jul 2.

Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/pros.23032
Publisher Site
http://dx.doi.org/10.1002/pros.23032DOI Listing
October 2015

Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer.

Clin Cancer Res 2015 Aug 18;21(15):3561-8. Epub 2015 Feb 18.

Clinical Translational Research Division, The Translational Genomics Research Institute, Phoenix, Arizona.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-14-1051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526394PMC
August 2015

Stromal expression of miR-21 identifies high-risk group in triple-negative breast cancer.

Am J Pathol 2014 Dec 6;184(12):3217-25. Epub 2014 Nov 6.

Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, Michigan; Laboratory of microRNA Diagnostics and Therapeutics, Van Andel Research Institute, Grand Rapids, Michigan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2014.08.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258602PMC
December 2014

Establishment of genetically diverse patient-derived xenografts of colorectal cancer.

Am J Cancer Res 2014 19;4(6):824-37. Epub 2014 Nov 19.

Laboratory of Systems Biology, Van Andel Research Institute Grand Rapids, MI 49503, USA ; Van Andel Institute Graduate School Grand Rapids, MI 49503, USA.

View Article

Download full-text PDF

Source
http://www.ajcr.us/files/ajcr0002438.pdf
Web Search
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266715PMC
December 2014

A pilot study using next-generation sequencing in advanced cancers: feasibility and challenges.

PLoS One 2013 30;8(10):e76438. Epub 2013 Oct 30.

Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare (VGPCC), Scottsdale, Arizona, United States of America ; The Translational Genomics Research Institute, Phoenix, Arizona, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0076438PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813699PMC
August 2014

Transient induction of ING4 by Myc drives prostate epithelial cell differentiation and its disruption drives prostate tumorigenesis.

Cancer Res 2014 Jun 24;74(12):3357-68. Epub 2014 Apr 24.

Authors' Affiliations: Laboratory of Integrin Signaling; Laboratory of Translational Imaging; and Laboratory of Analytical Pathology; and Van Andel Institute Graduate School, Grand Rapids; Genetics Graduate Program, Michigan State University, Lansing, Michigan; and Tranlational Genomics Research Institute and University of Arizona College of Medicine, Phoenix, Arizona

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-13-3076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066454PMC
June 2014

Negative regulation of NF-κB by the ING4 tumor suppressor in breast cancer.

PLoS One 2012 4;7(10):e46823. Epub 2012 Oct 4.

Cancer and Cell Biology Division, Translational Genomics Research Institute, Phoenix, Arizona, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0046823PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464231PMC
May 2013

Molecular Characterization of a Patient's Small Cell Carcinoma of the Ovary of the Hypercalcemic Type.

J Cancer 2012 26;3:58-66. Epub 2012 Jan 26.

1. Clinical Translational Research Division, Translational Genomics Research Institute, Phoenix, AZ, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7150/jca.3872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273708PMC
October 2012

Hedgehog signaling pathway molecules and ALDH1A1 expression in early-stage non-small cell lung cancer.

Lung Cancer 2012 May 23;76(2):191-6. Epub 2011 Nov 23.

Cancer and Cell Biology Division, The Translational Genomics Research Institute (TGen), Phoenix, AZ, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.lungcan.2011.10.015DOI Listing
May 2012

Quiescin sulfhydryl oxidase 1 promotes invasion of pancreatic tumor cells mediated by matrix metalloproteinases.

Mol Cancer Res 2011 Dec 11;9(12):1621-31. Epub 2011 Oct 11.

Arizona State University, School of Life Sciences, Tempe, AZ 85287, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-11-0018DOI Listing
December 2011

Perineural invasion and associated pain in pancreatic cancer.

Nat Rev Cancer 2011 Sep 23;11(10):695-707. Epub 2011 Sep 23.

Clinical Translational Research Division, Translational Genomics Research Institute, 13208 East Shea Boulevard, Scottsdale, Arizona 85259, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrc3131DOI Listing
September 2011

Targeting the tumor microenvironment in cancer: why hyaluronidase deserves a second look.

Cancer Discov 2011 Sep;1(4):291-6

Clinical Translational Research Division, The Translational Genomics Research Institute, Phoenix, Arizona, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2159-8290.CD-11-0136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204883PMC
September 2011

Genomic analysis by oligonucleotide array Comparative Genomic Hybridization utilizing formalin-fixed, paraffin-embedded tissues.

Methods Mol Biol 2011 ;700:185-98

Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/978-1-61737-954-3_13
Publisher Site
http://dx.doi.org/10.1007/978-1-61737-954-3_13DOI Listing
April 2011

Higher expression of the heterogeneous nuclear ribonucleoprotein k in melanoma.

Ann Surg Oncol 2010 Oct 25;17(10):2619-27. Epub 2010 May 25.

Department of Surgery, Arizona Cancer Center, University of Arizona, Tucson, AZ, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1245/s10434-010-1121-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943057PMC
October 2010

Identification of pancreatic cancer-specific cell-surface markers for development of targeting ligands.

Methods Mol Biol 2010 ;624:195-210

Molecular and Functional Imaging, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-60761-609-2_13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010309PMC
June 2010

Validation of TPX2 as a potential therapeutic target in pancreatic cancer cells.

Clin Cancer Res 2009 Nov 27;15(21):6519-28. Epub 2009 Oct 27.

Clinical Translational Research Division, Translational Genomics Research Institute, Phoenix, Arizona 85004, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-09-0077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783218PMC
November 2009

Small interfering RNA-mediated knockdown of PRL phosphatases results in altered Akt phosphorylation and reduced clonogenicity of pancreatic cancer cells.

Mol Cancer Ther 2008 Jan 9;7(1):202-10. Epub 2008 Jan 9.

Department of Molecular and Cellular Biology, University of Arizona, Tucson, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1535-7163.MCT-07-0542DOI Listing
January 2008

Tissue factor expression, angiogenesis, and thrombosis in pancreatic cancer.

Clin Cancer Res 2007 May;13(10):2870-5

James P. Wilmot Cancer Center, Department of Medicine, University of Rochester, Rochester, New York 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-06-2351DOI Listing
May 2007

Vascular endothelial growth factor and DPC4 predict adjuvant therapy outcomes in resected pancreatic cancer.

J Gastrointest Surg 2005 Sep-Oct;9(7):903-11

James P. Wilmot Cancer Center and the Department of Medicine, University of Rochester, Rochester, NY 14642, and the National Human Genomics Research Institute, National Institutes of Health, Bethesda, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gassur.2005.06.021DOI Listing
January 2006

Tissue microarrays: applications in genomic research.

Expert Rev Mol Diagn 2005 Mar;5(2):171-81

TMA Core Service, Translational Genomics Research Institute, 400 N. 5 Street, Phoenix AZ 85004, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1586/14737159.5.2.171DOI Listing
March 2005

Thymidylate synthase expression predicts the response to 5-fluorouracil-based adjuvant therapy in pancreatic cancer.

Clin Cancer Res 2003 Sep;9(11):4165-71

Department of Surgery, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA.

View Article

Download full-text PDF

Source
September 2003

High frequency of BRAF mutations in nevi.

Nat Genet 2003 Jan 25;33(1):19-20. Epub 2002 Nov 25.

Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, 50 South Drive, Bethesda, Maryland 20892, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/ng1054
Publisher Site
http://dx.doi.org/10.1038/ng1054DOI Listing
January 2003

Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma.

Cancer Cell 2002 Apr;1(3):279-88

National Human Genome Research Institute, Cancer Genetics Branch, National Institutes of Health, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s1535-6108(02)00045-4DOI Listing
April 2002