Gail V W Johnson

Gail V W Johnson

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Gail V W Johnson

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It's all about tau.

Prog Neurobiol 2019 Apr 31;175:54-76. Epub 2018 Dec 31.

Laboratory of Neurodegenerative Diseases, Centro de Investigación Biomédica, Universidad Autónoma de Chile, Santiago, Chile; Centro de Investigación y Estudio del Consumo de Alcohol en Adolescentes (CIIA), Santiago, Chile. Electronic address:

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http://dx.doi.org/10.1016/j.pneurobio.2018.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397676PMC
April 2019

Tissue Transglutaminase-Mediated AT1 Receptor Sensitization Underlies Pro-inflammatory Cytokine LIGHT-Induced Hypertension.

Am J Hypertens 2019 Apr;32(5):476-485

Department of Biochemistry and Molecular Biology, McGovern Medical School at Houston, University of Texas, Houston, Texas, USA.

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http://dx.doi.org/10.1093/ajh/hpz018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475879PMC
April 2019

Nuclear transglutaminase 2 directly regulates expression of cathepsin S in rat cortical neurons.

Eur J Neurosci 2018 Nov 6;48(9):3043-3051. Epub 2018 Oct 6.

Department of Anesthesiology and Perioperative Medicine, University of Rochester, Rochester, New York.

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http://dx.doi.org/10.1111/ejn.14159DOI Listing
November 2018

Depletion of astrocytic transglutaminase 2 improves injury outcomes.

Mol Cell Neurosci 2018 10 30;92:128-136. Epub 2018 Jun 30.

Department of Pharmacology and Physiology, University of Rochester, Rochester, NY 14642, USA; Department of Biomedical Genetics, University of Rochester, Rochester, NY 14642, USA; Department of Anesthesiology and Perioperative Medicine, University of Rochester, Rochester, NY 14642, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mcn.2018.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218936PMC
October 2018

Transglutaminase 2: Friend or foe? The discordant role in neurons and astrocytes.

J Neurosci Res 2018 Jul 23;96(7):1150-1158. Epub 2018 Mar 23.

Department of Pharmacology and Physiology, University of Rochester, Rochester, New York.

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http://dx.doi.org/10.1002/jnr.24239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980740PMC
July 2018

Assessing the degradation of tau in primary neurons: The role of autophagy.

Methods Cell Biol 2017 31;141:229-244. Epub 2017 Jul 31.

University of Rochester, Rochester, NY, Unites States. Electronic address:

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http://dx.doi.org/10.1016/bs.mcb.2017.06.011DOI Listing
June 2018

Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.

Neurobiol Aging 2018 03 9;63:128-139. Epub 2017 Dec 9.

Department of Anesthesiology, University of Rochester Medical Center, University of Rochester, Rochester, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801049PMC
March 2018

Depletion of transglutaminase 2 in neurons alters expression of extracellular matrix and signal transduction genes and compromises cell viability.

Mol Cell Neurosci 2018 01 29;86:72-80. Epub 2017 Nov 29.

Department of Anesthesiology and Perioperative Medicine, University of Rochester Medical Center, 601 Elmwood Ave, Box 604, Rochester, NY 14642, United States; Department of Pharmacology and Physiology, University of Rochester Medical Center, 601 Elmwood Ave, Box 604, Rochester, NY 14642, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10447431173026
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http://dx.doi.org/10.1016/j.mcn.2017.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736014PMC
January 2018

Subcellular localization patterns of transglutaminase 2 in astrocytes and neurons are differentially altered by hypoxia.

Neuroreport 2017 Dec;28(18):1208-1214

Departments of aNeuroscience bAnesthesiology, University of Rochester Medical Center, Rochester, New York, USA.

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http://dx.doi.org/10.1097/WNR.0000000000000895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685886PMC
December 2017

Transglutaminase 2 modulation of NF-κB signaling in astrocytes is independent of its ability to mediate astrocytic viability in ischemic injury.

Brain Res 2017 Aug 15;1668:1-11. Epub 2017 May 15.

Department of Neuroscience, University of Rochester Medical Center, 601 Elmwood Ave, Box 603, Rochester, NY 14642, United States; Department of Anesthesiology, University of Rochester Medical Center, 601 Elmwood Ave, Box 604, Rochester, NY 14642, United States. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2017.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525061PMC
August 2017

The complex role of transglutaminase 2 in glioblastoma proliferation.

Neuro Oncol 2017 Feb;19(2):208-218

Department of Anesthesiology, University of Rochester, Rochester, New York; Department of Pharmacology and Physiology, University of Rochester, Rochester, New York; Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1093/neuonc/now157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464277PMC
February 2017

Inhibition or ablation of transglutaminase 2 impairs astrocyte migration.

Biochem Biophys Res Commun 2017 Jan 27;482(4):942-947. Epub 2016 Nov 27.

Department of Pharmacology and Physiology, University of Rochester, Rochester, NY 14642, USA; Department of Anesthesiology, University of Rochester, Rochester, NY 14642, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.11.137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237609PMC
January 2017

Endostatin and transglutaminase 2 are involved in fibrosis of the aging kidney.

Kidney Int 2016 06 14;89(6):1281-92. Epub 2016 Apr 14.

Department of Medicine, Renal Research Institute, New York Medical College, Valhalla, New York, USA; Department of Pharmacology, Renal Research Institute, New York Medical College, Valhalla, New York, USA; Department of Physiology, Renal Research Institute, New York Medical College, Valhalla, New York, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2016.01.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868664PMC
June 2016

Fisetin stimulates autophagic degradation of phosphorylated tau via the activation of TFEB and Nrf2 transcription factors.

Sci Rep 2016 04 26;6:24933. Epub 2016 Apr 26.

Division of Brain Diseases, Center for Biomedical Sciences, Cheongju-si, Chungcheongbuk-do 363-951, Korea.

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http://dx.doi.org/10.1038/srep24933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844953PMC
April 2016

Mechanisms of tau and Aβ-induced excitotoxicity.

Brain Res 2016 Mar 28;1634:119-131. Epub 2015 Dec 28.

Department of Anesthesiology, University of Rochester Medical Center, Rochester, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2015.12.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779680PMC
March 2016

Tau facilitates Aβ-induced loss of mitochondrial membrane potential independent of cytosolic calcium fluxes in mouse cortical neurons.

Neurosci Lett 2015 Jun 15;597:32-7. Epub 2015 Apr 15.

Department of Anesthesiology, University of Rochester Medical Center, Rochester, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neulet.2015.04.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442715PMC
June 2015

BAG3 facilitates the clearance of endogenous tau in primary neurons.

Neurobiol Aging 2015 Jan 16;36(1):241-8. Epub 2014 Aug 16.

Department of Anesthesiology, University of Rochester Medical Center, University of Rochester, Rochester, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268232PMC
January 2015

Phosphorylated tau potentiates Aβ-induced mitochondrial damage in mature neurons.

Neurobiol Dis 2014 Nov 16;71:260-9. Epub 2014 Aug 16.

Department of Anesthesiology, University of Rochester Medical Center, Rochester, NY, USA.

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http://dx.doi.org/10.1016/j.nbd.2014.08.016DOI Listing
November 2014

NDP52 associates with phosphorylated tau in brains of an Alzheimer disease mouse model.

Biochem Biophys Res Commun 2014 Nov 18;454(1):196-201. Epub 2014 Oct 18.

Division of Brain Diseases, Center for Biomedical Sciences, Korea National Institute of Health, 187 Osongsaengmyeong2(i)-ro, Osong-eup, Chungju-si, Chungcheongbuk-do 363-951, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.10.066DOI Listing
November 2014

Sulforaphane induces autophagy through ERK activation in neuronal cells.

FEBS Lett 2014 Aug 18;588(17):3081-8. Epub 2014 Jun 18.

Division of Brain Diseases, Center for Biomedical Sciences, Korea National Institute of Health, 187 Osongsaengmyeong2(i)-ro, Osong-eup, Cheongwon-gun, Chungcheongbuk-do 363-951, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.febslet.2014.06.036DOI Listing
August 2014

Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52.

Nat Commun 2014 Mar 25;5:3496. Epub 2014 Mar 25.

Department of Anesthesiology, University of Rochester Medical Center, University of Rochester, 601 Elmwood Avenue, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1038/ncomms4496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990284PMC
March 2014

Mitochondrial permeability transition pore induces mitochondria injury in Huntington disease.

Mol Neurodegener 2013 Dec 11;8:45. Epub 2013 Dec 11.

Department of Anesthesiology, University of Rochester Medical Center, 601 Elmwood Ave, Box 604 (for courier: Rm 4-6314), Rochester, NY 14642, USA.

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http://dx.doi.org/10.1186/1750-1326-8-45DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878840PMC
December 2013

Tau clearance mechanisms and their possible role in the pathogenesis of Alzheimer disease.

Front Neurol 2013 Sep 3;4:122. Epub 2013 Sep 3.

Neuroscience Graduate Program, Department of Anesthesiology, University of Rochester , Rochester, NY , USA.

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http://dx.doi.org/10.3389/fneur.2013.00122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759803PMC
September 2013

Transglutaminase 2 facilitates or ameliorates HIF signaling and ischemic cell death depending on its conformation and localization.

Biochim Biophys Acta 2013 Jan 17;1833(1):1-10. Epub 2012 Oct 17.

Department of Anesthesiology, University of Rochester, Rochester, NY, USA.

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http://dx.doi.org/10.1016/j.bbamcr.2012.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518673PMC
January 2013

Metabolic state determines sensitivity to cellular stress in Huntington disease: normalization by activation of PPARγ.

PLoS One 2012 20;7(1):e30406. Epub 2012 Jan 20.

Department of Pharmacology and Physiology, University of Rochester, Rochester, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0030406PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262812PMC
June 2012

Vena cava and aortic smooth muscle cells express transglutaminases 1 and 4 in addition to transglutaminase 2.

Am J Physiol Heart Circ Physiol 2012 Apr 3;302(7):H1355-66. Epub 2012 Feb 3.

Department of Pharmacology and Toxicology, Michigan State University, East Lansing, 48824, USA.

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http://dx.doi.org/10.1152/ajpheart.00918.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330795PMC
April 2012

Guidelines for the use and interpretation of assays for monitoring autophagy.

Authors:
Daniel J Klionsky Fabio C Abdalla Hagai Abeliovich Robert T Abraham Abraham Acevedo-Arozena Khosrow Adeli Lotta Agholme Maria Agnello Patrizia Agostinis Julio A Aguirre-Ghiso Hyung Jun Ahn Ouardia Ait-Mohamed Slimane Ait-Si-Ali Takahiko Akematsu Shizuo Akira Hesham M Al-Younes Munir A Al-Zeer Matthew L Albert Roger L Albin Javier Alegre-Abarrategui Maria Francesca Aleo Mehrdad Alirezaei Alexandru Almasan Maylin Almonte-Becerril Atsuo Amano Ravi Amaravadi Shoba Amarnath Amal O Amer Nathalie Andrieu-Abadie Vellareddy Anantharam David K Ann Shailendra Anoopkumar-Dukie Hiroshi Aoki Nadezda Apostolova Giuseppe Arancia John P Aris Katsuhiko Asanuma Nana Y O Asare Hisashi Ashida Valerie Askanas David S Askew Patrick Auberger Misuzu Baba Steven K Backues Eric H Baehrecke Ben A Bahr Xue-Yuan Bai Yannick Bailly Robert Baiocchi Giulia Baldini Walter Balduini Andrea Ballabio Bruce A Bamber Edward T W Bampton Gábor Bánhegyi Clinton R Bartholomew Diane C Bassham Robert C Bast Henri Batoko Boon-Huat Bay Isabelle Beau Daniel M Béchet Thomas J Begley Christian Behl Christian Behrends Soumeya Bekri Bryan Bellaire Linda J Bendall Luca Benetti Laura Berliocchi Henri Bernardi Francesca Bernassola Sébastien Besteiro Ingrid Bhatia-Kissova Xiaoning Bi Martine Biard-Piechaczyk Janice S Blum Lawrence H Boise Paolo Bonaldo David L Boone Beat C Bornhauser Karina R Bortoluci Ioannis Bossis Frédéric Bost Jean-Pierre Bourquin Patricia Boya Michaël Boyer-Guittaut Peter V Bozhkov Nathan R Brady Claudio Brancolini Andreas Brech Jay E Brenman Ana Brennand Emery H Bresnick Patrick Brest Dave Bridges Molly L Bristol Paul S Brookes Eric J Brown John H Brumell Nicola Brunetti-Pierri Ulf T Brunk Dennis E Bulman Scott J Bultman Geert Bultynck Lena F Burbulla Wilfried Bursch Jonathan P Butchar Wanda Buzgariu Sergio P Bydlowski Ken Cadwell Monika Cahová Dongsheng Cai Jiyang Cai Qian Cai Bruno Calabretta Javier Calvo-Garrido Nadine Camougrand Michelangelo Campanella Jenny Campos-Salinas Eleonora Candi Lizhi Cao Allan B Caplan Simon R Carding Sandra M Cardoso Jennifer S Carew Cathleen R Carlin Virginie Carmignac Leticia A M Carneiro Serena Carra Rosario A Caruso Giorgio Casari Caty Casas Roberta Castino Eduardo Cebollero Francesco Cecconi Jean Celli Hassan Chaachouay Han-Jung Chae Chee-Yin Chai David C Chan Edmond Y Chan Raymond Chuen-Chung Chang Chi-Ming Che Ching-Chow Chen Guang-Chao Chen Guo-Qiang Chen Min Chen Quan Chen Steve S-L Chen WenLi Chen Xi Chen Xiangmei Chen Xiequn Chen Ye-Guang Chen Yingyu Chen Yongqiang Chen Yu-Jen Chen Zhixiang Chen Alan Cheng Christopher H K Cheng Yan Cheng Heesun Cheong Jae-Ho Cheong Sara Cherry Russ Chess-Williams Zelda H Cheung Eric Chevet Hui-Ling Chiang Roberto Chiarelli Tomoki Chiba Lih-Shen Chin Shih-Hwa Chiou Francis V Chisari Chi Hin Cho Dong-Hyung Cho Augustine M K Choi DooSeok Choi Kyeong Sook Choi Mary E Choi Salem Chouaib Divaker Choubey Vinay Choubey Charleen T Chu Tsung-Hsien Chuang Sheau-Huei Chueh Taehoon Chun Yong-Joon Chwae Mee-Len Chye Roberto Ciarcia Maria R Ciriolo Michael J Clague Robert S B Clark Peter G H Clarke Robert Clarke Patrice Codogno Hilary A Coller María I Colombo Sergio Comincini Maria Condello Fabrizio Condorelli Mark R Cookson Graham H Coombs Isabelle Coppens Ramon Corbalan Pascale Cossart Paola Costelli Safia Costes Ana Coto-Montes Eduardo Couve Fraser P Coxon James M Cregg José L Crespo Marianne J Cronjé Ana Maria Cuervo Joseph J Cullen Mark J Czaja Marcello D'Amelio Arlette Darfeuille-Michaud Lester M Davids Faith E Davies Massimo De Felici John F de Groot Cornelis A M de Haan Luisa De Martino Angelo De Milito Vincenzo De Tata Jayanta Debnath Alexei Degterev Benjamin Dehay Lea M D Delbridge Francesca Demarchi Yi Zhen Deng Jörn Dengjel Paul Dent Donna Denton Vojo Deretic Shyamal D Desai Rodney J Devenish Mario Di Gioacchino Gilbert Di Paolo Chiara Di Pietro Guillermo Díaz-Araya Inés Díaz-Laviada Maria T Diaz-Meco Javier Diaz-Nido Ivan Dikic Savithramma P Dinesh-Kumar Wen-Xing Ding Clark W Distelhorst Abhinav Diwan Mojgan Djavaheri-Mergny Svetlana Dokudovskaya Zheng Dong Frank C Dorsey Victor Dosenko James J Dowling Stephen Doxsey Marlène Dreux Mark E Drew Qiuhong Duan Michel A Duchosal Karen Duff Isabelle Dugail Madeleine Durbeej Michael Duszenko Charles L Edelstein Aimee L Edinger Gustavo Egea Ludwig Eichinger N Tony Eissa Suhendan Ekmekcioglu Wafik S El-Deiry Zvulun Elazar Mohamed Elgendy Lisa M Ellerby Kai Er Eng Anna-Mart Engelbrecht Simone Engelender Jekaterina Erenpreisa Ricardo Escalante Audrey Esclatine Eeva-Liisa Eskelinen Lucile Espert Virginia Espina Huizhou Fan Jia Fan Qi-Wen Fan Zhen Fan Shengyun Fang Yongqi Fang Manolis Fanto Alessandro Fanzani Thomas Farkas Jean-Claude Farré Mathias Faure Marcus Fechheimer Carl G Feng Jian Feng Qili Feng Youji Feng László Fésüs Ralph Feuer Maria E Figueiredo-Pereira Gian Maria Fimia Diane C Fingar Steven Finkbeiner Toren Finkel Kim D Finley Filomena Fiorito Edward A Fisher Paul B Fisher Marc Flajolet Maria L Florez-McClure Salvatore Florio Edward A Fon Francesco Fornai Franco Fortunato Rati Fotedar Daniel H Fowler Howard S Fox Rodrigo Franco Lisa B Frankel Marc Fransen José M Fuentes Juan Fueyo Jun Fujii Kozo Fujisaki Eriko Fujita Mitsunori Fukuda Ruth H Furukawa Matthias Gaestel Philippe Gailly Malgorzata Gajewska Brigitte Galliot Vincent Galy Subramaniam Ganesh Barry Ganetzky Ian G Ganley Fen-Biao Gao George F Gao Jinming Gao Lorena Garcia Guillermo Garcia-Manero Mikel Garcia-Marcos Marjan Garmyn Andrei L Gartel Evelina Gatti Mathias Gautel Thomas R Gawriluk Matthew E Gegg Jiefei Geng Marc Germain Jason E Gestwicki David A Gewirtz Saeid Ghavami Pradipta Ghosh Anna M Giammarioli Alexandra N Giatromanolaki Spencer B Gibson Robert W Gilkerson Michael L Ginger Henry N Ginsberg Jakub Golab Michael S Goligorsky Pierre Golstein Candelaria Gomez-Manzano Ebru Goncu Céline Gongora Claudio D Gonzalez Ramon Gonzalez Cristina González-Estévez Rosa Ana González-Polo Elena Gonzalez-Rey Nikolai V Gorbunov Sharon Gorski Sandro Goruppi Roberta A Gottlieb Devrim Gozuacik Giovanna Elvira Granato Gary D Grant Kim N Green Aleš Gregorc Frédéric Gros Charles Grose Thomas W Grunt Philippe Gual Jun-Lin Guan Kun-Liang Guan Sylvie M Guichard Anna S Gukovskaya Ilya Gukovsky Jan Gunst Asa B Gustafsson Andrew J Halayko Amber N Hale Sandra K Halonen Maho Hamasaki Feng Han Ting Han Michael K Hancock Malene Hansen Hisashi Harada Masaru Harada Stefan E Hardt J Wade Harper Adrian L Harris James Harris Steven D Harris Makoto Hashimoto Jeffrey A Haspel Shin-ichiro Hayashi Lori A Hazelhurst Congcong He You-Wen He Marie-Joseé Hébert Kim A Heidenreich Miep H Helfrich Gudmundur V Helgason Elizabeth P Henske Brian Herman Paul K Herman Claudio Hetz Sabine Hilfiker Joseph A Hill Lynne J Hocking Paul Hofman Thomas G Hofmann Jörg Höhfeld Tessa L Holyoake Ming-Huang Hong David A Hood Gökhan S Hotamisligil Ewout J Houwerzijl Maria Høyer-Hansen Bingren Hu Chien-An A Hu Hong-Ming Hu Ya Hua Canhua Huang Ju Huang Shengbing Huang Wei-Pang Huang Tobias B Huber Won-Ki Huh Tai-Ho Hung Ted R Hupp Gang Min Hur James B Hurley Sabah N A Hussain Patrick J Hussey Jung Jin Hwang Seungmin Hwang Atsuhiro Ichihara Shirin Ilkhanizadeh Ken Inoki Takeshi Into Valentina Iovane Juan L Iovanna Nancy Y Ip Yoshitaka Isaka Hiroyuki Ishida Ciro Isidoro Ken-ichi Isobe Akiko Iwasaki Marta Izquierdo Yotaro Izumi Panu M Jaakkola Marja Jäättelä George R Jackson William T Jackson Bassam Janji Marina Jendrach Ju-Hong Jeon Eui-Bae Jeung Hong Jiang Hongchi Jiang Jean X Jiang Ming Jiang Qing Jiang Xuejun Jiang Xuejun Jiang Alberto Jiménez Meiyan Jin Shengkan Jin Cheol O Joe Terje Johansen Daniel E Johnson Gail V W Johnson Nicola L Jones Bertrand Joseph Suresh K Joseph Annie M Joubert Gábor Juhász Lucienne Juillerat-Jeanneret Chang Hwa Jung Yong-Keun Jung Kai Kaarniranta Allen Kaasik Tomohiro Kabuta Motoni Kadowaki Katarina Kagedal Yoshiaki Kamada Vitaliy O Kaminskyy Harm H Kampinga Hiromitsu Kanamori Chanhee Kang Khong Bee Kang Kwang Il Kang Rui Kang Yoon-A Kang Tomotake Kanki Thirumala-Devi Kanneganti Haruo Kanno Anumantha G Kanthasamy Arthi Kanthasamy Vassiliki Karantza Gur P Kaushal Susmita Kaushik Yoshinori Kawazoe Po-Yuan Ke John H Kehrl Ameeta Kelekar Claus Kerkhoff David H Kessel Hany Khalil Jan A K W Kiel Amy A Kiger Akio Kihara Deok Ryong Kim Do-Hyung Kim Dong-Hou Kim Eun-Kyoung Kim Hyung-Ryong Kim Jae-Sung Kim Jeong Hun Kim Jin Cheon Kim John K Kim Peter K Kim Seong Who Kim Yong-Sun Kim Yonghyun Kim Adi Kimchi Alec C Kimmelman Jason S King Timothy J Kinsella Vladimir Kirkin Lorrie A Kirshenbaum Katsuhiko Kitamoto Kaio Kitazato Ludger Klein Walter T Klimecki Jochen Klucken Erwin Knecht Ben C B Ko Jan C Koch Hiroshi Koga Jae-Young Koh Young Ho Koh Masato Koike Masaaki Komatsu Eiki Kominami Hee Jeong Kong Wei-Jia Kong Viktor I Korolchuk Yaichiro Kotake Michael I Koukourakis Juan B Kouri Flores Attila L Kovács Claudine Kraft Dimitri Krainc Helmut Krämer Carole Kretz-Remy Anna M Krichevsky Guido Kroemer Rejko Krüger Oleg Krut Nicholas T Ktistakis Chia-Yi Kuan Roza Kucharczyk Ashok Kumar Raj Kumar Sharad Kumar Mondira Kundu Hsing-Jien Kung Tino Kurz Ho Jeong Kwon Albert R La Spada Frank Lafont Trond Lamark Jacques Landry Jon D Lane Pierre Lapaquette Jocelyn F Laporte Lajos László Sergio Lavandero Josée N Lavoie Robert Layfield Pedro A Lazo Weidong Le Laurent Le Cam Daniel J Ledbetter Alvin J X Lee Byung-Wan Lee Gyun Min Lee Jongdae Lee Ju-Hyun Lee Michael Lee Myung-Shik Lee Sug Hyung Lee Christiaan Leeuwenburgh Patrick Legembre Renaud Legouis Michael Lehmann Huan-Yao Lei Qun-Ying Lei David A Leib José Leiro John J Lemasters Antoinette Lemoine Maciej S Lesniak Dina Lev Victor V Levenson Beth Levine Efrat Levy Faqiang Li Jun-Lin Li Lian Li Sheng Li Weijie Li Xue-Jun Li Yan-bo Li Yi-Ping Li Chengyu Liang Qiangrong Liang Yung-Feng Liao Pawel P Liberski Andrew Lieberman Hyunjung J Lim Kah-Leong Lim Kyu Lim Chiou-Feng Lin Fu-Cheng Lin Jian Lin Jiandie D Lin Kui Lin Wan-Wan Lin Weei-Chin Lin Yi-Ling Lin Rafael Linden Paul Lingor Jennifer Lippincott-Schwartz Michael P Lisanti Paloma B Liton Bo Liu Chun-Feng Liu Kaiyu Liu Leyuan Liu Qiong A Liu Wei Liu Young-Chau Liu Yule Liu Richard A Lockshin Chun-Nam Lok Sagar Lonial Benjamin Loos Gabriel Lopez-Berestein Carlos López-Otín Laura Lossi Michael T Lotze Peter Lőw Binfeng Lu Bingwei Lu Bo Lu Zhen Lu Frédéric Luciano Nicholas W Lukacs Anders H Lund Melinda A Lynch-Day Yong Ma Fernando Macian Jeff P MacKeigan Kay F Macleod Frank Madeo Luigi Maiuri Maria Chiara Maiuri Davide Malagoli May Christine V Malicdan Walter Malorni Na Man Eva-Maria Mandelkow Stéphen Manon Irena Manov Kai Mao Xiang Mao Zixu Mao Philippe Marambaud Daniela Marazziti Yves L Marcel Katie Marchbank Piero Marchetti Stefan J Marciniak Mateus Marcondes Mohsen Mardi Gabriella Marfe Guillermo Mariño Maria Markaki Mark R Marten Seamus J Martin Camille Martinand-Mari Wim Martinet Marta Martinez-Vicente Matilde Masini Paola Matarrese Saburo Matsuo Raffaele Matteoni Andreas Mayer Nathalie M Mazure David J McConkey Melanie J McConnell Catherine McDermott Christine McDonald Gerald M McInerney Sharon L McKenna BethAnn McLaughlin Pamela J McLean Christopher R McMaster G Angus McQuibban Alfred J Meijer Miriam H Meisler Alicia Meléndez Thomas J Melia Gerry Melino Maria A Mena Javier A Menendez Rubem F S Menna-Barreto Manoj B Menon Fiona M Menzies Carol A Mercer Adalberto Merighi Diane E Merry Stefania Meschini Christian G Meyer Thomas F Meyer Chao-Yu Miao Jun-Ying Miao Paul A M Michels Carine Michiels Dalibor Mijaljica Ana Milojkovic Saverio Minucci Clelia Miracco Cindy K Miranti Ioannis Mitroulis Keisuke Miyazawa Noboru Mizushima Baharia Mograbi Simin Mohseni Xavier Molero Bertrand Mollereau Faustino Mollinedo Takashi Momoi Iryna Monastyrska Martha M Monick Mervyn J Monteiro Michael N Moore Rodrigo Mora Kevin Moreau Paula I Moreira Yuji Moriyasu Jorge Moscat Serge Mostowy Jeremy C Mottram Tomasz Motyl Charbel E-H Moussa Sylke Müller Sylviane Muller Karl Münger Christian Münz Leon O Murphy Maureen E Murphy Antonio Musarò Indira Mysorekar Eiichiro Nagata Kazuhiro Nagata Aimable Nahimana Usha Nair Toshiyuki Nakagawa Kiichi Nakahira Hiroyasu Nakano Hitoshi Nakatogawa Meera Nanjundan Naweed I Naqvi Derek P Narendra Masashi Narita Miguel Navarro Steffan T Nawrocki Taras Y Nazarko Andriy Nemchenko Mihai G Netea Thomas P Neufeld Paul A Ney Ioannis P Nezis Huu Phuc Nguyen Daotai Nie Ichizo Nishino Corey Nislow Ralph A Nixon Takeshi Noda Angelika A Noegel Anna Nogalska Satoru Noguchi Lucia Notterpek Ivana Novak Tomoyoshi Nozaki Nobuyuki Nukina Thorsten Nürnberger Beat Nyfeler Keisuke Obara Terry D Oberley Salvatore Oddo Michinaga Ogawa Toya Ohashi Koji Okamoto Nancy L Oleinick F Javier Oliver Laura J Olsen Stefan Olsson Onya Opota Timothy F Osborne Gary K Ostrander Kinya Otsu Jing-hsiung James Ou Mireille Ouimet Michael Overholtzer Bulent Ozpolat Paolo Paganetti Ugo Pagnini Nicolas Pallet Glen E Palmer Camilla Palumbo Tianhong Pan 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Yoshikawa Tamotsu Yoshimori Kohki Yoshimoto Ho Jin You Richard J Youle Anas Younes Li Yu Long Yu Seong-Woon Yu Wai Haung Yu Zhi-Min Yuan Zhenyu Yue Cheol-Heui Yun Michisuke Yuzaki Olga Zabirnyk Elaine Silva-Zacarin David Zacks Eldad Zacksenhaus Nadia Zaffaroni Zahra Zakeri Herbert J Zeh Scott O Zeitlin Hong Zhang Hui-Ling Zhang Jianhua Zhang Jing-Pu Zhang Lin Zhang Long Zhang Ming-Yong Zhang Xu Dong Zhang Mantong Zhao Yi-Fang Zhao Ying Zhao Zhizhuang J Zhao Xiaoxiang Zheng Boris Zhivotovsky Qing Zhong Cong-Zhao Zhou Changlian Zhu Wei-Guo Zhu Xiao-Feng Zhu Xiongwei Zhu Yuangang Zhu Teresa Zoladek Wei-Xing Zong Antonio Zorzano Jürgen Zschocke Brian Zuckerbraun

Autophagy 2012 Apr;8(4):445-544

Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.

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April 2012

Truncated tau and Aβ cooperatively impair mitochondria in primary neurons.

Neurobiol Aging 2012 Mar 29;33(3):619.e25-35. Epub 2011 Mar 29.

Department of Anesthesiology, University of Rochester, Rochester, NY 14642, USA.

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March 2012

Complete transglutaminase 2 ablation results in reduced stroke volumes and astrocytes that exhibit increased survival in response to ischemia.

Neurobiol Dis 2012 Mar 14;45(3):1042-50. Epub 2011 Dec 14.

Department of Pharmacology and Physiology, 601 Elmwood Avenue, Box 711, University of Rochester, Rochester, NY 14642, USA.

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March 2012

Transglutaminase 2: a molecular Swiss army knife.

Biochim Biophys Acta 2012 Feb 10;1823(2):406-19. Epub 2011 Oct 10.

Department of Pharmacology, University of Rochester, 601 Elmwood Ave., Rochester, NY 14642, USA.

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February 2012

Decreases in valosin-containing protein result in increased levels of tau phosphorylated at Ser262/356.

FEBS Lett 2011 Nov 5;585(21):3424-9. Epub 2011 Oct 5.

Department of Pharmacology and Physiology, University of Rochester, Rochester, NY, USA.

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November 2011

Transglutaminase 2 and its role in pulmonary fibrosis.

Am J Respir Crit Care Med 2011 Sep 23;184(6):699-707. Epub 2011 Jun 23.

University of Rochester, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Rochester, NY 14642, USA.

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September 2011

The toxicity of tau in Alzheimer disease: turnover, targets and potential therapeutics.

J Cell Mol Med 2011 Aug;15(8):1621-35

Department of Anesthesiology and the Interdepartmental Graduate Program in Neuroscience, University of Rochester, Rochester, NY, USA.

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August 2011

The application of permanent middle cerebral artery ligation in the mouse.

J Vis Exp 2011 Jul 25(53). Epub 2011 Jul 25.

Department of Pharmacology and Physiology, University of Rochester, USA.

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July 2011

Split GFP complementation assay for quantitative measurement of tau aggregation in situ.

Methods Mol Biol 2011 ;670:109-23

Department of Pharmacology, College of Medicine, Kangwon National University, Chunchon, Korea.

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May 2011

Cytosolic guanine nucledotide binding deficient form of transglutaminase 2 (R580a) potentiates cell death in oxygen glucose deprivation.

PLoS One 2011 Jan 31;6(1):e16665. Epub 2011 Jan 31.

Department of Pharmacology and Physiology, University of Rochester, Rochester, New York, United States of America.

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January 2011

AES/GRG5: more than just a dominant-negative TLE/GRG family member.

Dev Dyn 2010 Nov;239(11):2795-805

Department of Anesthesiology, University of Rochester, Rochester, New York 14642, USA.

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November 2010

The role of tau kinases in Alzheimer's disease.

Curr Opin Drug Discov Devel 2010 Sep;13(5):595-603

University of Alabama at Birmingham, Department of Cell Biology, 1530 3rd Avenue South, Birmingham, AL 35294, USA.

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September 2010

A caspase cleaved form of tau is preferentially degraded through the autophagy pathway.

J Biol Chem 2010 Jul 13;285(29):21978-87. Epub 2010 May 13.

Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.

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July 2010

Differential modulation of TCF/LEF-1 activity by the soluble LRP6-ICD.

PLoS One 2010 Jul 28;5(7):e11821. Epub 2010 Jul 28.

Department of Anesthesiology and Pharmacology, University of Rochester, Rochester, New York, United States of America.

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July 2010

The interrelationship between mitochondrial dysfunction and transcriptional dysregulation in Huntington disease.

J Bioenerg Biomembr 2010 Jun;42(3):199-205

Department of Anesthesiology, University of Rochester, 601 Elmwood Ave, Box 604, Rochester, NY 14642, USA.

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June 2010

Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease.

Brain Res Bull 2009 Oct 19;80(4-5):242-7. Epub 2009 Jul 19.

Department of Anesthesiology, University of Rochester, Rochester, NY 14642-0002, USA.

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October 2009

Intracellular localization and conformational state of transglutaminase 2: implications for cell death.

PLoS One 2009 Jul 1;4(7):e6123. Epub 2009 Jul 1.

Department of Pharmacology and Physiology, University of Rochester, Rochester, NY, USA.

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July 2009

Increased expression of Bim contributes to the potentiation of serum deprivation-induced apoptotic cell death in Huntington's disease knock-in striatal cell line.

Neurol Res 2009 Feb 7;31(1):77-83. Epub 2008 Aug 7.

Department of Pharmacology, College of Medicine, Kangwon National University, Chunchon, Korea.

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February 2009

Immortalized cortical neurons expressing caspase-cleaved tau are sensitized to endoplasmic reticulum stress induced cell death.

Brain Res 2008 Oct 7;1234:206-12. Epub 2008 Aug 7.

Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL 35294-0017, USA.

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October 2008

Histone deacetylase 6 interacts with the microtubule-associated protein tau.

J Neurochem 2008 Sep 12;106(5):2119-30. Epub 2008 Jul 12.

Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA.

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September 2008

Transglutaminase 2 protects against ischemic insult, interacts with HIF1beta, and attenuates HIF1 signaling.

FASEB J 2008 Aug 28;22(8):2662-75. Epub 2008 Mar 28.

Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA.

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August 2008

New application of beta-galactosidase complementation to monitor tau self-association.

J Neurochem 2008 Aug 28;106(4):1545-51. Epub 2008 Jun 28.

Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA.

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August 2008

The last tangle of tau.

J Alzheimers Dis 2008 Aug;14(4):441-7

Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL, USA.

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August 2008

Split GFP complementation assay: a novel approach to quantitatively measure aggregation of tau in situ: effects of GSK3beta activation and caspase 3 cleavage.

J Neurochem 2007 Dec 1;103(6):2529-39. Epub 2007 Oct 1.

Department of Psychiatry, University of Alabama at Birmingham School of Medicine, Alabama, USA.

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December 2007

Mitochondrial-targeted active Akt protects SH-SY5Y neuroblastoma cells from staurosporine-induced apoptotic cell death.

J Cell Biochem 2007 Sep;102(1):196-210

Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.

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September 2007

Activation of glycogen synthase kinase 3beta promotes the intermolecular association of tau. The use of fluorescence resonance energy transfer microscopy.

J Biol Chem 2007 Aug 12;282(32):23410-7. Epub 2007 Jun 12.

Department of Psychiatry, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama 35294, USA.

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August 2007

Type 2 transglutaminase differentially modulates striatal cell death in the presence of wild type or mutant huntingtin.

J Neurochem 2007 Jul 30;102(1):25-36. Epub 2007 Mar 30.

Department of Psychiatry, University of Alabama at Birmingham, Birmingham, Alabama 35294-0017, USA.

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July 2007

Ubiquitin-proteasome system alterations in a striatal cell model of Huntington's disease.

J Neurosci Res 2007 Jun;85(8):1774-88

Department of Cell Biology, and Department of Psychiatry, The University of Alabama at Birmingham, Birmingham, Alabama, USA.

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June 2007

Regulated proteolytic processing of LRP6 results in release of its intracellular domain.

J Neurochem 2007 Apr 26;101(2):517-29. Epub 2007 Feb 26.

Department of Psychiatry, University of Alabama at Birmingham, Birmingham, Alabama 35294-0017, USA.

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April 2007

The role of tau phosphorylation and cleavage in neuronal cell death.

Front Biosci 2007 Jan 1;12:733-56. Epub 2007 Jan 1.

Department of Psychiatry, School of Medicine, University of Alabama at Birmingham, 1061 Sparks Center, 1720 7th Avenue South, Birmingham, AL 35294-0017, USA.

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http://dx.doi.org/10.2741/2097DOI Listing
January 2007

Transglutaminase 2 in neurodegenerative disorders.

Front Biosci 2007 Jan 1;12:891-904. Epub 2007 Jan 1.

Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, 1720 Seventh Avenue South, SC1061, Birmingham, AL 35294-0017, USA.

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January 2007

Tau is hyperphosphorylated at multiple sites in mouse brain in vivo after streptozotocin-induced insulin deficiency.

Diabetes 2006 Dec;55(12):3320-5

Department of Psychiatry and Behavioral Neurobiology, 1720 Seventh Ave. South, Sparks Center 1057, University of Alabama, Birmingham, AL 35294-0017, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851885PMC
December 2006

The role of tau phosphorylation in the pathogenesis of Alzheimer's disease.

Curr Alzheimer Res 2006 Dec;3(5):449-63

Department of Psychiatry, University of Alabama at Birmingham, Birmingham, AL 35294-0017, USA.

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December 2006

Mutant huntingtin expression induces mitochondrial calcium handling defects in clonal striatal cells: functional consequences.

J Biol Chem 2006 Nov 13;281(46):34785-95. Epub 2006 Sep 13.

Department of Psychiatry, University of Alabama at Birmingham, Birmingham, Alabama 35294-0017, USA.

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November 2006

Tau phosphorylation and proteolysis: insights and perspectives.

Authors:
Gail V W Johnson

J Alzheimers Dis 2006 ;9(3 Suppl):243-50

Department of Psychiatry, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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October 2006

Site-specific phosphorylation and caspase cleavage differentially impact tau-microtubule interactions and tau aggregation.

J Biol Chem 2006 Jul 10;281(28):19107-14. Epub 2006 May 10.

Department of Psychiatry, University of Alabama, Birmingham, Alabama 35294-0017, USA.

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http://dx.doi.org/10.1074/jbc.M511697200DOI Listing
July 2006

The protective effects of cystamine in the R6/2 Huntington's disease mouse involve mechanisms other than the inhibition of tissue transglutaminase.

Neurobiol Aging 2006 Jun;27(6):871-9

Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, 1720 7th Avenue South, Sparks Center Room 1061, Birmingham, AL 35294-0017, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2005.04.001DOI Listing
June 2006

Tissue transglutaminase overexpression in the brain potentiates calcium-induced hippocampal damage.

J Neurochem 2006 Apr 15;97(2):582-94. Epub 2006 Mar 15.

Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, 35294, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2006.03780.xDOI Listing
April 2006

The low density lipoprotein receptor-related protein 6 interacts with glycogen synthase kinase 3 and attenuates activity.

J Biol Chem 2006 Feb 19;281(8):4787-94. Epub 2005 Dec 19.

Department of Psychiatry, University of Alabama at Birmingham, Birmingham, Alabama 35294-0017, USA.

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http://dx.doi.org/10.1074/jbc.M508657200DOI Listing
February 2006

Cystamine treatment is neuroprotective in the YAC128 mouse model of Huntington disease.

J Neurochem 2005 Oct;95(1):210-20

Centre for Molecular Medicine and Therapeutics, Department of Medical Genetics and British Columbia Research Institute for Women and Children's Health, University of British Columbia, Vancouver, British Columbia, Canada.

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October 2005

Mitochondrial respiration and ATP production are significantly impaired in striatal cells expressing mutant huntingtin.

J Biol Chem 2005 Sep 27;280(35):30773-82. Epub 2005 Jun 27.

Department of Psychiatry, University of Alabama at Birmingham, Birmingham, Alabama 35294-0017, USA.

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September 2005

Increased glutathione levels in cortical and striatal mitochondria of the R6/2 Huntington's disease mouse model.

Neurosci Lett 2005 Sep;386(1):63-8

Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL 35294-0017, USA.

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http://dx.doi.org/10.1016/j.neulet.2005.05.065DOI Listing
September 2005

14-3-3Zeta does not increase GSK3beta-mediated tau phosphorylation in cell culture models.

Neurosci Lett 2005 Aug;384(3):211-6

Department of Psychiatry, School of Medicine, 1720 7th Avenue South, SC1061, University of Alabama at Birmingham, Birmingham, AL 35294-0017, USA.

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http://dx.doi.org/10.1016/j.neulet.2005.04.101DOI Listing
August 2005

Transglutaminases in neurodegenerative disorders.

Prog Exp Tumor Res 2005 ;38:139-57

Department of Psychiatry, University of Alabama at Birmingham-School of Medicine, 1720 7th Avenue South, Birmingham, AL 35294-0017, USA.

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http://dx.doi.org/10.1159/000084238DOI Listing
May 2005

Role of the intracellular domains of LRP5 and LRP6 in activating the Wnt canonical pathway.

J Cell Biochem 2005 May;95(2):328-38

Department of Psychiatry, University of Alabama at Birmingham, Alabama 35294-0017, USA.

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http://dx.doi.org/10.1002/jcb.20400DOI Listing
May 2005

Verification of somatic CAG repeat expansion by pre-PCR fractionation.

J Neurosci Methods 2005 May 28;144(1):11-7. Epub 2004 Nov 28.

Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.1016/j.jneumeth.2004.10.006DOI Listing
May 2005

FRAT-2 preferentially increases glycogen synthase kinase 3 beta-mediated phosphorylation of primed sites, which results in enhanced tau phosphorylation.

J Biol Chem 2005 Jan 1;280(1):270-6. Epub 2004 Nov 1.

Department of Psychiatry, University of Alabama at Birmingham, Alabama 35294-0017, USA.

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http://dx.doi.org/10.1074/jbc.M410061200DOI Listing
January 2005

Tissue transglutaminase contributes to disease progression in the R6/2 Huntington's disease mouse model via aggregate-independent mechanisms.

J Neurochem 2005 Jan;92(1):83-92

Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, Alabama 35294-0017, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2004.02839.xDOI Listing
January 2005

Tau phosphorylation: physiological and pathological consequences.

Biochim Biophys Acta 2005 Jan;1739(2-3):280-97

Department of Psychiatry, School of Medicine, University of Alabama at Birmingham, 1061 Sparks Center, 1720 7th Avenue South, Birmingham, AL 35294-0017, USA.

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http://dx.doi.org/10.1016/j.bbadis.2004.06.017DOI Listing
January 2005

Glycogen synthase kinase 3 beta induces caspase-cleaved tau aggregation in situ.

J Biol Chem 2004 Dec 19;279(52):54716-23. Epub 2004 Oct 19.

Department of Psychiatry, University of Alabama at Birmingham, Alabama 35294-0017, USA.

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http://dx.doi.org/10.1074/jbc.M403364200DOI Listing
December 2004

Developmental regulation of tissue transglutaminase in the mouse forebrain.

J Neurochem 2004 Dec;91(6):1369-79

Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2004.02825.xDOI Listing
December 2004

Tau phosphorylation in neuronal cell function and dysfunction.

J Cell Sci 2004 Nov;117(Pt 24):5721-9

Department of Psychiatry, University of Alabama at Birmingham, Birmingham, AL 35294-0017, USA.

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http://dx.doi.org/10.1242/jcs.01558DOI Listing
November 2004

Tissue transglutaminase is not involved in the aggregate formation of stably expressed alpha-synuclein in SH-SY5Y human neuroblastoma cells.

Arch Pharm Res 2004 Aug;27(8):850-6

Department of Pharmacology, College of Medicine, Kangwon National University, Chunchon 200-701, Korea.

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http://dx.doi.org/10.1007/bf02980178DOI Listing
August 2004

Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release.

Hum Mol Genet 2004 Jul 26;13(14):1407-20. Epub 2004 May 26.

Department of Psychiatry, University of Alabama at Birmingham, 35294, USA.

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http://dx.doi.org/10.1093/hmg/ddh162DOI Listing
July 2004

Striatal cells from mutant huntingtin knock-in mice are selectively vulnerable to mitochondrial complex II inhibitor-induced cell death through a non-apoptotic pathway.

Hum Mol Genet 2004 Apr 12;13(7):669-81. Epub 2004 Feb 12.

Department of Psychiatry, University of Alabama at Birmingham, Birmingham, AL 35294-0017, USA.

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http://dx.doi.org/10.1093/hmg/ddh082DOI Listing
April 2004

Immunoblot analysis reveals that isopeptide antibodies do not specifically recognize the epsilon-(gamma-glutamyl)lysine bonds formed by transglutaminase activity.

J Neurosci Methods 2004 Apr;134(2):151-8

Department of Psychiatry, School of Medicine 1720, University of Alabama at Birmingham, 7th Avenue South, SC1061, Birmingham, AL 35294-0017, USA.

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http://dx.doi.org/10.1016/j.jneumeth.2003.11.006DOI Listing
April 2004

Effects of cyclin-dependent kinase-5 activity on apoptosis and tau phosphorylation in immortalized mouse brain cortical cells.

J Neurosci Res 2004 Apr;76(1):110-20

Department of Psychiatry, University of Alabama at Birmingham, Birmingham, Alabama 35294-0001, USA.

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http://dx.doi.org/10.1002/jnr.20051DOI Listing
April 2004

Intracellular localization and activity state of tissue transglutaminase differentially impacts cell death.

J Biol Chem 2004 Mar 11;279(10):8715-22. Epub 2003 Dec 11.

Department of Psychiatry, University of Alabama at Birmingham, Alabama 35294-0017, USA.

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http://dx.doi.org/10.1074/jbc.M308479200DOI Listing
March 2004

Cyclin-dependent kinase-5 in neurodegeneration.

J Neurochem 2004 Mar;88(6):1313-26

Department of Psychiatry, University of Alabama at Birmingham, Birmingham, Alabama, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2003.02328.xDOI Listing
March 2004

Validity of mouse models for the study of tissue transglutaminase in neurodegenerative diseases.

Mol Cell Neurosci 2004 Mar;25(3):493-503

Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294-0017, USA.

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http://dx.doi.org/10.1016/j.mcn.2003.11.016DOI Listing
March 2004

Mutant (R406W) human tau is hyperphosphorylated and does not efficiently bind microtubules in a neuronal cortical cell model.

J Biol Chem 2004 Feb 2;279(9):7893-900. Epub 2003 Dec 2.

Department of Psychiatry, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.

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http://dx.doi.org/10.1074/jbc.M311203200DOI Listing
February 2004

The glamour and gloom of glycogen synthase kinase-3.

Trends Biochem Sci 2004 Feb;29(2):95-102

Department of Psychiatry and Behavioral Neurobiology, Sparks Center 1057, University of Alabama at Birmingham, Birmingham, AL 35294-0017, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S09680004030032
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http://dx.doi.org/10.1016/j.tibs.2003.12.004DOI Listing
February 2004

Primed phosphorylation of tau at Thr231 by glycogen synthase kinase 3beta (GSK3beta) plays a critical role in regulating tau's ability to bind and stabilize microtubules.

J Neurochem 2004 Jan;88(2):349-58

Department of Psychiatry, University of Alabama at Birmingham, Birmingham, Alabama 35294-0017, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2004.02155.xDOI Listing
January 2004

The p38 MAP kinase signaling pathway in Alzheimer's disease.

Exp Neurol 2003 Oct;183(2):263-8

Department of Psychiatry, University of Alabama at Birmingham, Birmingham, AL 35294-0017, USA.

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http://dx.doi.org/10.1016/s0014-4886(03)00268-1DOI Listing
October 2003

Tissue transglutaminase directly regulates adenylyl cyclase resulting in enhanced cAMP-response element-binding protein (CREB) activation.

J Biol Chem 2003 Jul 12;278(29):26838-43. Epub 2003 May 12.

Department of Psychiatry, University of Alabama at Birmingham, Birmingham, Alabama 35294-0017, USA.

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http://dx.doi.org/10.1074/jbc.M303683200DOI Listing
July 2003