Gagan B Panigrahi

Gagan B Panigrahi

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Gagan B Panigrahi

Gagan B Panigrahi

Publications by authors named "Gagan B Panigrahi"

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Absence of MutSβ leads to the formation of slipped-DNA for CTG/CAG contractions at primate replication forks.

DNA Repair (Amst) 2016 06 16;42:107-18. Epub 2016 Apr 16.

Program of Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario M5G 1L7, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5G 1L7, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15687864153011
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http://dx.doi.org/10.1016/j.dnarep.2016.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096786PMC
June 2016

An infant with MLH3 variants, FOXG1-duplication and multiple, benign cranial and spinal tumors: A clinical exome sequencing study.

Genes Chromosomes Cancer 2016 Feb 6;55(2):131-42. Epub 2015 Nov 6.

Pathology and Laboratory Medicine, University of California at Los Angeles, David Geffen School of Medicine, Los Angeles, CA, 90095.

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http://dx.doi.org/10.1002/gcc.22319DOI Listing
February 2016

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers.

Nat Genet 2015 Mar 2;47(3):257-62. Epub 2015 Feb 2.

1] Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada. [2] The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada. [3] Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada. [4] Department of Pediatrics, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/ng.3202DOI Listing
March 2015

Processing of double-R-loops in (CAG)·(CTG) and C9orf72 (GGGGCC)·(GGCCCC) repeats causes instability.

Nucleic Acids Res 2014 21;42(16):10473-87. Epub 2014 Aug 21.

Department of Genetics, The Hospital for Sick Children, Peter Gilgan Centre for Research & Learning, 686 Bay Street, Toronto, Ontario M5G 0A4, Canada Program of Molecular Genetics, University of Toronto, Toronto, Ontario M5G 0A4, Canada

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http://dx.doi.org/10.1093/nar/gku658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176329PMC
January 2015

Human mismatch repair protein hMutLα is required to repair short slipped-DNAs of trinucleotide repeats.

J Biol Chem 2012 Dec 18;287(50):41844-50. Epub 2012 Oct 18.

Department of Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M112.420398
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http://dx.doi.org/10.1074/jbc.M112.420398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516732PMC
December 2012

Maternal germline-specific effect of DNA ligase I on CTG/CAG instability.

Hum Mol Genet 2011 Jun 5;20(11):2131-43. Epub 2011 Mar 5.

Program of Genetics and Genome Biology, The Hospital for Sick Children Research Institute, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1093/hmg/ddr099DOI Listing
June 2011

Tissue- and age-specific DNA replication patterns at the CTG/CAG-expanded human myotonic dystrophy type 1 locus.

Nat Struct Mol Biol 2010 Sep 15;17(9):1079-87. Epub 2010 Aug 15.

Program of Genetics & Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/nsmb.1876DOI Listing
September 2010

Isolated short CTG/CAG DNA slip-outs are repaired efficiently by hMutSbeta, but clustered slip-outs are poorly repaired.

Proc Natl Acad Sci U S A 2010 Jul 22;107(28):12593-8. Epub 2010 Jun 22.

Program of Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada M5G 1L7.

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http://www.pnas.org/lookup/doi/10.1073/pnas.0909087107
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http://dx.doi.org/10.1073/pnas.0909087107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906547PMC
July 2010

Mutagenic roles of DNA "repair" proteins in antibody diversity and disease-associated trinucleotide repeat instability.

DNA Repair (Amst) 2008 Jul 16;7(7):1135-54. Epub 2008 May 16.

Program of Genetics & Genome Biology, The Hospital for Sick Children, Toronto, Ontario, Canada M5G 1L7.

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http://dx.doi.org/10.1016/j.dnarep.2008.03.014DOI Listing
July 2008

Slipped (CTG)*(CAG) repeats can be correctly repaired, escape repair or undergo error-prone repair.

Nat Struct Mol Biol 2005 Aug 17;12(8):654-62. Epub 2005 Jul 17.

Program of Genetics & Genomic Biology, The Hospital for Sick Children, 555 University Avenue, Elm Wing 11-135, Toronto, Ontario M5G 1X8, Canada.

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http://dx.doi.org/10.1038/nsmb959DOI Listing
August 2005

In vitro (CTG)*(CAG) expansions and deletions by human cell extracts.

J Biol Chem 2002 Apr 6;277(16):13926-34. Epub 2002 Feb 6.

Program of Genetics and Genomic Biology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario M5A 1X8, Canada.

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http://dx.doi.org/10.1074/jbc.M109761200DOI Listing
April 2002