Gaetano Finocchiaro

Gaetano Finocchiaro

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Gaetano Finocchiaro

Gaetano Finocchiaro

Publications by authors named "Gaetano Finocchiaro"

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98Publications

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MRI in Glioma Immunotherapy: Evidence, Pitfalls, and Perspectives.

J Immunol Res 2017 20;2017:5813951. Epub 2017 Apr 20.

Neuroradiology Unit, Fondazione IRCCS Istituto Neurologico "Carlo Besta", Milan, Italy.

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March 2018

Genetic Evolution of Glioblastoma Stem-Like Cells From Primary to Recurrent Tumor.

Stem Cells 2017 11 29;35(11):2218-2228. Epub 2017 Sep 29.

Laboratory of Cancer Stem Cell Research, Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.

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November 2017

Diffuse glioblastoma resembling acute hemorrhagic leukoencephalitis.

Quant Imaging Med Surg 2017 Oct;7(5):592-597

Unit of Neuroradiology, Department of Advanced Biomedical Sciences, "Federico II" University, Naples, Italy.

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October 2017

Identification and characterization of a new source of adult human neural progenitors.

Cell Death Dis 2017 08 10;8(8):e2991. Epub 2017 Aug 10.

Vilhelm Magnus Laboratory of Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway.

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August 2017

Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.

Cancer Cell 2017 07;32(1):42-56.e6

Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA. Electronic address:

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July 2017

Intertumoral Heterogeneity within Medulloblastoma Subgroups.

Authors:
Florence M G Cavalli Marc Remke Ladislav Rampasek John Peacock David J H Shih Betty Luu Livia Garzia Jonathon Torchia Carolina Nor A Sorana Morrissy Sameer Agnihotri Yuan Yao Thompson Claudia M Kuzan-Fischer Hamza Farooq Keren Isaev Craig Daniels Byung-Kyu Cho Seung-Ki Kim Kyu-Chang Wang Ji Yeoun Lee Wieslawa A Grajkowska Marta Perek-Polnik Alexandre Vasiljevic Cecile Faure-Conter Anne Jouvet Caterina Giannini Amulya A Nageswara Rao Kay Ka Wai Li Ho-Keung Ng Charles G Eberhart Ian F Pollack Ronald L Hamilton G Yancey Gillespie James M Olson Sarah Leary William A Weiss Boleslaw Lach Lola B Chambless Reid C Thompson Michael K Cooper Rajeev Vibhakar Peter Hauser Marie-Lise C van Veelen Johan M Kros Pim J French Young Shin Ra Toshihiro Kumabe Enrique López-Aguilar Karel Zitterbart Jaroslav Sterba Gaetano Finocchiaro Maura Massimino Erwin G Van Meir Satoru Osuka Tomoko Shofuda Almos Klekner Massimo Zollo Jeffrey R Leonard Joshua B Rubin Nada Jabado Steffen Albrecht Jaume Mora Timothy E Van Meter Shin Jung Andrew S Moore Andrew R Hallahan Jennifer A Chan Daniela P C Tirapelli Carlos G Carlotti Maryam Fouladi José Pimentel Claudia C Faria Ali G Saad Luca Massimi Linda M Liau Helen Wheeler Hideo Nakamura Samer K Elbabaa Mario Perezpeña-Diazconti Fernando Chico Ponce de León Shenandoah Robinson Michal Zapotocky Alvaro Lassaletta Annie Huang Cynthia E Hawkins Uri Tabori Eric Bouffet Ute Bartels Peter B Dirks James T Rutka Gary D Bader Jüri Reimand Anna Goldenberg Vijay Ramaswamy Michael D Taylor

Cancer Cell 2017 06;31(6):737-754.e6

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A1, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada. Electronic address:

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June 2017

TLRgeting Evasion of Immune Pathways in Glioblastoma.

Cell Stem Cell 2017 04;20(4):422-424

Unit of Molecular Neuro-Oncology, Foundation IRCCS Neurological Institute Carlo Besta, 20133 Milan, Italy. Electronic address:

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April 2017

Hypermutations in gliomas: a potential immunotherapy target.

Discov Med 2017 02;23(125):113-120

Unit of Molecular Neuro-Oncology, Fondazione IRCCS Istituto Neurologico Besta, 20133 Milano, Italy.

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February 2017

Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase II Study of Onartuzumab Plus Bevacizumab Versus Placebo Plus Bevacizumab in Patients With Recurrent Glioblastoma: Efficacy, Safety, and Hepatocyte Growth Factor and O-Methylguanine-DNA Methyltransferase Biomarker Analyses.

J Clin Oncol 2017 Jan 5;35(3):343-351. Epub 2016 Dec 5.

Timothy Cloughesy, University of California, Los Angeles; Lawrence Recht, Stanford Cancer Center, Stanford; Carlos Bais, Thomas Sandmann, Jean-Marie Bruey, Hartmut Koeppen, Bo Liu, Wendy Verret, See-Chun Phan, and David S. Shames, Genentech, South San Francisco, CA; Tom Mikkelsen, Henry Ford Hospital, Detroit, MI; Gaetano Finocchiaro, Istituto Neurologico Carlo Besta, Milan; Alba A. Brandes, Azienda Unità Sanitaria Locale-Istituto di Ricovero e Cura a Carattere Scientifico Institute of Neurologic Sciences, Bologna, Italy; Cristóbal Belda-Iniesta, Centro Integral Oncológico Clara Campal, University Hospital HM Sanchinarro, Madrid; Estela Pineda, Hospital Clinic of Barcelona; Carmen Balana, Institut Català d'Oncologia Badalona Hospital Germans Trias I Pujol, Barcelona, Spain; Olivier L. Chinot, Aix-Marseille Université Assistance Publique-Hôpitaux de Marseille, Marseille, France; David R. Macdonald, London Health Sciences Centre, London, Ontario, Canada; Manfred Westphal, University Clinic Hamburg-Eppendorf, Hamburg, Germany; Kirsten Hopkins, Bristol Haematology and Oncology Centre, Bristol, United Kingdom; and Michael Weller, University Hospital Zurich, Zurich, Switzerland.

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January 2017

Principles of immunotherapy.

Handb Clin Neurol 2016 ;134:163-81

Department of Neurosurgery, University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

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December 2016

Human glioblastoma stem-like cells accumulate protoporphyrin IX when subjected to exogenous 5-aminolaevulinic acid, rendering them sensitive to photodynamic treatment.

J Photochem Photobiol B 2016 Oct 27;163:203-10. Epub 2016 Aug 27.

Institute for Transplantation Diagnostics and Cell Therapeutics, Heinrich-Heine University Hospital Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany. Electronic address:

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October 2016

A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways.

Nat Commun 2016 10 4;7:12885. Epub 2016 Oct 4.

Department of Neurology, Northwestern Brain Tumor Institute, The Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA.

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October 2016

AVAREG: a phase II, randomized, noncomparative study of fotemustine or bevacizumab for patients with recurrent glioblastoma.

Neuro Oncol 2016 09 6;18(9):1304-12. Epub 2016 Mar 6.

Department of Medical Oncology, Bellaria-Maggiore Hospital, Azienda USL-IRCCS Institute of Neurological Sciences, Bologna, Italy (A.A.B., E.F.); Molecular Neuro-Oncology Unit, IRCCS Foundation Carlo Besta, Milan, Italy (G.F., M.E.); Department of Clinical and Experimental Oncology, Medical Oncology, Veneto Institute of Oncology- IRCCS Padua, Italy (V.Z., G.L.); Department of Medical Oncology, IRCCS San Raffaele, Milan, Italy (M.R.); Oncology Department, Santa Maria Hospital, Terni, Italy (C.C.); Department of Medical Oncology, Regina Elena National Cancer Institute, Rome, Italy (A.F.); E.O. Ospedale Galliera, Genova, Italy (M.C.); Oncology Unit, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy (E.M.); OPIS, Palazzo Aliprandi, Desio MB, Italy (M.M.); Roche S.p.A. Medical Affairs and CO, Monza, Italy (E.P.); Neuroradiology Department, Bellaria-Maggiore Hospital, Azienda USL-IRCCS Institute of Neurological Sciences, Ospedale Bellaria, Bologna, Italy (R.A.); Department of Biomedical and Neuromotor Science, University of Bologna, Section of Anatomic Pathology M. Malpighi-Bellaria Hospital, Bologna, Italy (V.E.).

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September 2016

Ultrasonic Surgical Aspirate is a Reliable Source For Culturing Glioblastoma Stem Cells.

Sci Rep 2016 09 8;6:32788. Epub 2016 Sep 8.

Norwegian Center for Stem Cell Research, Department of Immunology, Oslo University Hospital, 1112 Blindern 0317 OSLO, Norway.

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September 2016

Novel mechanisms and approaches in immunotherapy for brain tumors.

Discov Med 2015 Jul-Aug;20(108):7-15

Unit of Molecular Neuro-Oncology, Fondazione IRCCS Istituto Neurologico Besta, via Celoria 11, 20133 Milano, Italy.

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May 2016

Immunotherapy with dendritic cells loaded with glioblastoma stem cells: from preclinical to clinical studies.

Cancer Immunol Immunother 2016 Jan 16;65(1):101-9. Epub 2015 Sep 16.

Unit of Molecular Neuro-Oncology, Fondazione I.R.C.C.S. Istituto Neurologico C. Besta, Via Celoria 11, 20133, Milan, Italy.

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January 2016

126 novel mutations in Italian patients with neurofibromatosis type 1.

Mol Genet Genomic Med 2015 Nov 7;3(6):513-25. Epub 2015 Jul 7.

Molecular Neuro-oncology IRCCS Foundation, "C. Besta" Neurological Institute Milan Italy.

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November 2015

Safe and Reproducible Preparation of Functional Dendritic Cells for Immunotherapy in Glioblastoma Patients.

Stem Cells Transl Med 2015 Oct 13;4(10):1164-72. Epub 2015 Aug 13.

Cell Therapy Production Unit, Laboratory of Cellular Neurobiology, Cerebrovascular Unit, and Unit of Molecular Neuro-Oncology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.

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October 2015

Erratum to: Extraneural metastases in glioblastoma patients: two cases with YKL-40-positive glioblastomas and a meta-analysis of the literature.

Neurosurg Rev 2015 Oct;38(4):773

Unit of Neurology VIII-Molecular Neuro-Oncology, Foundation, I.R.C.C.S., Neurological National Institute C. Besta, Milan, Italy,

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October 2015

Radiosurgery reirradiation for high-grade glioma recurrence: a retrospective analysis.

Neurol Sci 2015 Aug 25;36(8):1431-40. Epub 2015 Mar 25.

Radiotherapy Unit, Neurosurgery Department, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, MI, Italy,

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August 2015

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

Authors:
Daniel J Brat Roel G W Verhaak Kenneth D Aldape W K Alfred Yung Sofie R Salama Lee A D Cooper Esther Rheinbay C Ryan Miller Mark Vitucci Olena Morozova A Gordon Robertson Houtan Noushmehr Peter W Laird Andrew D Cherniack Rehan Akbani Jason T Huse Giovanni Ciriello Laila M Poisson Jill S Barnholtz-Sloan Mitchel S Berger Cameron Brennan Rivka R Colen Howard Colman Adam E Flanders Caterina Giannini Mia Grifford Antonio Iavarone Rajan Jain Isaac Joseph Jaegil Kim Katayoon Kasaian Tom Mikkelsen Bradley A Murray Brian Patrick O'Neill Lior Pachter Donald W Parsons Carrie Sougnez Erik P Sulman Scott R Vandenberg Erwin G Van Meir Andreas von Deimling Hailei Zhang Daniel Crain Kevin Lau David Mallery Scott Morris Joseph Paulauskis Robert Penny Troy Shelton Mark Sherman Peggy Yena Aaron Black Jay Bowen Katie Dicostanzo Julie Gastier-Foster Kristen M Leraas Tara M Lichtenberg Christopher R Pierson Nilsa C Ramirez Cynthia Taylor Stephanie Weaver Lisa Wise Erik Zmuda Tanja Davidsen John A Demchok Greg Eley Martin L Ferguson Carolyn M Hutter Kenna R Mills Shaw Bradley A Ozenberger Margi Sheth Heidi J Sofia Roy Tarnuzzer Zhining Wang Liming Yang Jean Claude Zenklusen Brenda Ayala Julien Baboud Sudha Chudamani Mark A Jensen Jia Liu Todd Pihl Rohini Raman Yunhu Wan Ye Wu Adrian Ally J Todd Auman Miruna Balasundaram Saianand Balu Stephen B Baylin Rameen Beroukhim Moiz S Bootwalla Reanne Bowlby Christopher A Bristow Denise Brooks Yaron Butterfield Rebecca Carlsen Scott Carter Lynda Chin Andy Chu Eric Chuah Kristian Cibulskis Amanda Clarke Simon G Coetzee Noreen Dhalla Tim Fennell Sheila Fisher Stacey Gabriel Gad Getz Richard Gibbs Ranabir Guin Angela Hadjipanayis D Neil Hayes Toshinori Hinoue Katherine Hoadley Robert A Holt Alan P Hoyle Stuart R Jefferys Steven Jones Corbin D Jones Raju Kucherlapati Phillip H Lai Eric Lander Semin Lee Lee Lichtenstein Yussanne Ma Dennis T Maglinte Harshad S Mahadeshwar Marco A Marra Michael Mayo Shaowu Meng Matthew L Meyerson Piotr A Mieczkowski Richard A Moore Lisle E Mose Andrew J Mungall Angeliki Pantazi Michael Parfenov Peter J Park Joel S Parker Charles M Perou Alexei Protopopov Xiaojia Ren Jeffrey Roach Thaís S Sabedot Jacqueline Schein Steven E Schumacher Jonathan G Seidman Sahil Seth Hui Shen Janae V Simons Payal Sipahimalani Matthew G Soloway Xingzhi Song Huandong Sun Barbara Tabak Angela Tam Donghui Tan Jiabin Tang Nina Thiessen Timothy Triche David J Van Den Berg Umadevi Veluvolu Scot Waring Daniel J Weisenberger Matthew D Wilkerson Tina Wong Junyuan Wu Liu Xi Andrew W Xu Lixing Yang Travis I Zack Jianhua Zhang B Arman Aksoy Harindra Arachchi Chris Benz Brady Bernard Daniel Carlin Juok Cho Daniel DiCara Scott Frazer Gregory N Fuller JianJiong Gao Nils Gehlenborg David Haussler David I Heiman Lisa Iype Anders Jacobsen Zhenlin Ju Sol Katzman Hoon Kim Theo Knijnenburg Richard Bailey Kreisberg Michael S Lawrence William Lee Kalle Leinonen Pei Lin Shiyun Ling Wenbin Liu Yingchun Liu Yuexin Liu Yiling Lu Gordon Mills Sam Ng Michael S Noble Evan Paull Arvind Rao Sheila Reynolds Gordon Saksena Zack Sanborn Chris Sander Nikolaus Schultz Yasin Senbabaoglu Ronglai Shen Ilya Shmulevich Rileen Sinha Josh Stuart S Onur Sumer Yichao Sun Natalie Tasman Barry S Taylor Doug Voet Nils Weinhold John N Weinstein Da Yang Kosuke Yoshihara Siyuan Zheng Wei Zhang Lihua Zou Ty Abel Sara Sadeghi Mark L Cohen Jenny Eschbacher Eyas M Hattab Aditya Raghunathan Matthew J Schniederjan Dina Aziz Gene Barnett Wendi Barrett Darell D Bigner Lori Boice Cathy Brewer Chiara Calatozzolo Benito Campos Carlos Gilberto Carlotti Timothy A Chan Lucia Cuppini Erin Curley Stefania Cuzzubbo Karen Devine Francesco DiMeco Rebecca Duell J Bradley Elder Ashley Fehrenbach Gaetano Finocchiaro William Friedman Jordonna Fulop Johanna Gardner Beth Hermes Christel Herold-Mende Christine Jungk Ady Kendler Norman L Lehman Eric Lipp Ouida Liu Randy Mandt Mary McGraw Roger Mclendon Christopher McPherson Luciano Neder Phuong Nguyen Ardene Noss Raffaele Nunziata Quinn T Ostrom Cheryl Palmer Alessandro Perin Bianca Pollo Alexander Potapov Olga Potapova W Kimryn Rathmell Daniil Rotin Lisa Scarpace Cathy Schilero Kelly Senecal Kristen Shimmel Vsevolod Shurkhay Suzanne Sifri Rosy Singh Andrew E Sloan Kathy Smolenski Susan M Staugaitis Ruth Steele Leigh Thorne Daniela P C Tirapelli Andreas Unterberg Mahitha Vallurupalli Yun Wang Ronald Warnick Felicia Williams Yingli Wolinsky Sue Bell Mara Rosenberg Chip Stewart Franklin Huang Jonna L Grimsby Amie J Radenbaugh Jianan Zhang

N Engl J Med 2015 Jun 10;372(26):2481-98. Epub 2015 Jun 10.

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June 2015

DNA damage in mammalian neural stem cells leads to astrocytic differentiation mediated by BMP2 signaling through JAK-STAT.

Stem Cell Reports 2013 25;1(2):123-38. Epub 2013 Jul 25.

IFOM Foundation-The FIRC Institute of Molecular Oncology Foundation, Via Adamello 16, 20139 Milan, Italy.

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May 2015

EGFR amplified and overexpressing glioblastomas and association with better response to adjuvant metronomic temozolomide.

J Natl Cancer Inst 2015 May 3;107(5). Epub 2015 Mar 3.

Pathology (MC, BL, MFB, DM, VP, FF, PLP) and Pharmacology Units (CB, MP), Department of Molecular and Translational Medicine, University of Brescia and National Institute of Neuroscience, Italy; Medical Oncology (SG), Neurosurgery (LB), Radiation Oncology (MB), and Neuroradiology Departments (RL), Spedali Civili of Brescia, University of Brescia, Italy; Neural Stem Cell Biology Unit, Division of Regenerative Medicine, Stem Cells & Gene Therapy, San Raffaele Scientific Institute, Milan (SM, RG); Pathology Unit, Department of Surgical and Morphological Sciences, University of Insubria, Italy (DF); Neurological Institute Besta, Milan, Italy (SP, GF); Herbert Irving Comprehensive Cancer Center, Department of Pathology & Cell Biology and Department of Medicine, Division of Digestive and Liver Diseases, Columbia University, New York, NY (PD); IRCCS San Camillo Hospital, Venice, Italy (MP).

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May 2015

Perspectives for immunotherapy in glioblastoma treatment.

Curr Opin Oncol 2014 Nov;26(6):608-14

Unit of Molecular Neuro-Oncology, Fondazione I.R.C.C.S. Istituto Neurologico C. Besta, Milano, Italy.

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November 2014

Accuracy of 2-hydroxyglutarate quantification by short-echo proton-MRS at 3 T: a phantom study.

Phys Med 2014 Sep 28;30(6):702-7. Epub 2014 Mar 28.

Scientific Department, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy. Electronic address:

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September 2014

Combined analysis of TERT, EGFR, and IDH status defines distinct prognostic glioblastoma classes.

Neurology 2014 Sep 22;83(13):1200-6. Epub 2014 Aug 22.

From Sorbonne Universités (M.L., B.B., K.M., A.-L.D.S., A.R., M.R., P.C., O.S., M.S.), UPMC Univ Paris 06, Inserm, CNRS, UM 75, U 1127, UMR 7225, ICM, Paris; Institut du Cerveau et de la Moelle épinière (ICM) (B.B., Y.M.), Plateforme de Génotypage Séquençage, Paris; Groupe Hospitalier Pitié Salpêtrière, Laboratoire de Neuropathologie R Escourolle (K.M.), Onconeurothèque (K.M., Y.M., M.S.), and Groupe Hospitalier Pitié-Salpêtrière, Service de Neurologie 2 (A.-L.D.S., M.S.), AP-HP, Paris, France; National Neurological Institute C. Mondino (A.-L.D.S.), Pavia; Department of Neuroscience (M.R., P.C.), University of Padova; and Unit of Molecular Neuro-Oncology (R.P., G.F.), Fondazione IRCCS Carlo Besta, Milan, Italy.

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September 2014

Survival effect of first- and second-line treatments for patients with primary glioblastoma: a cohort study from a prospective registry, 1997-2010.

Neuro Oncol 2014 May 23;16(5):719-27. Epub 2014 Jan 23.

Unit of Neuroepidemiology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy (F.N., I.T., A.F., M.F., G.F.); Unit of Neuroradiology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy (M.G.B., L.F.); Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy; Department of Neurological Surgery, Johns Hopkins Medical School, Baltimore, Maryland (F.D.); Unit of Molecular Neuro-oncology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy (G.F.); Unit of Neuropathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy (B.P.); Department of Neurology, Ospedale Alessandro Manzoni, Lecco, Italy (A.S.); Unit of Clinical Neuro-oncology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy (A.S.).

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May 2014

Sox2 is required to maintain cancer stem cells in a mouse model of high-grade oligodendroglioma.

Cancer Res 2014 Mar 5;74(6):1833-44. Epub 2014 Mar 5.

Authors' Affiliations: Department of Biotechnology and Biosciences, University of Milano-Bicocca; Department of Molecular Neuro-Oncology, Fondazione I.R.C.C.S. Istituto Neurologico C.Besta; Department of Experimental Oncology, European Institute of Oncology at IFOM-IEO Campus; Tissue Processing Unit, The FIRC Institute of Molecular Oncology Foundation-IFOM, IFOM-IEO Campus, Milano; and IRCCS Azienda Ospedaliera Universitaria San Martino, IST Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy.

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March 2014

Operability of glioblastomas: "sins of action" versus "sins of non-action".

Neurol Sci 2013 Dec 12;34(12):2107-16. Epub 2013 Mar 12.

Department of Neurosurgery, Fondazione Istituto Neurologico Carlo Besta, Via Celoria 11, 20133, Milan, Italy,

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December 2013

Frequency of NFKBIA deletions is low in glioblastomas and skewed in glioblastoma neurospheres.

Mol Cancer 2013 Dec 11;12:160. Epub 2013 Dec 11.

Molecular Neuro-Oncology Unit, IRCCS Foundation "C,Besta" Neurological Institute, via Celoria 11, 20133 Milan, Italy.

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December 2013

Central nervous system lymphoma occurring in a patient with neurofibromatosis type 1 (von Recklinghausen disease).

Neurol Sci 2012 Dec;33(6):1429-33

Fondazione I.R.C.C.S. Istituto Neurologico C. Besta, Unit of Molecular Neuro-Oncology, Milan, Italy.

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December 2012

FOXP3, a novel glioblastoma oncosuppressor, affects proliferation and migration.

Oncotarget 2012 Oct 22;3(10):1146-57. Epub 2012 Sep 22.

Unit of Molecular Neuro-Oncology, Fondazione I.R.C.C.S. Istituto Neurologico C. Besta, Milan, Italy.

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October 2012

The MET oncogene is a functional marker of a glioblastoma stem cell subtype.

Cancer Res 2012 Sep 26;72(17):4537-50. Epub 2012 Jun 26.

IRCC-Institute for Cancer Research, Center for Experimental Clinical Molecular Oncology, University of Turin Medical School, Candiolo, Italy.

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September 2012

Immunotherapy against the radial glia marker GLAST effectively triggers specific antitumor effectors without autoimmunity.

Oncoimmunology 2012 Sep;1(6):884-893

Unit of Molecular Neuro-Oncology; Neurological Institute C. Besta; Milan, Italy ; Department of Experimental Oncology; European Institute of Oncology; Campus IFOM-IEO; Milan, Italy.

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September 2012

FABP4 is a candidate marker of cerebellar liponeurocytomas.

J Neurooncol 2012 Jul 3;108(3):513-9. Epub 2012 Apr 3.

Unit of Molecular Neuro-oncology, Fondazione IRCCS C. Besta, Via Celoria 11, 20133, Milan, Italy.

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July 2012

NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma.

Oncotarget 2012 Jul;3(7):723-34

Unit of Molecular Neuro-Oncology, Fondazione I.R.C.C.S. Istituto Neurologico C. Besta, Milan, Italy.

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July 2012

Expression profile of frizzled receptors in human medulloblastomas.

J Neurooncol 2012 Jan 18;106(2):271-80. Epub 2011 Aug 18.

UO Neuro-oncologia Molecolare-Neurologia VIII, Fondazione IRCCS, Istituto Neurologico "C. Besta", Via Celoria 11, 20133 Milan, Italy.

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January 2012

A critical role for regulatory T cells in driving cytokine profiles of Th17 cells and their modulation of glioma microenvironment.

Cancer Immunol Immunother 2011 Dec 21;60(12):1739-50. Epub 2011 Jul 21.

Unit of Molecular Neuro-Oncology, Fondazione I.R.C.C.S. Istituto Neurologico C. Besta, via Celoria 11, 20133 Milan, Italy.

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December 2011

Immunotherapy for glioma: getting closer to the clinical arena?

Curr Opin Neurol 2011 Dec;24(6):641-7

Unit of Molecular Neuro-Oncology, Fondazione I.R.C.C.S. Istituto Neurologico C. Besta, IFOM-IEO Campus, Milan, Italy.

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December 2011

Brain cancer immunoediting: novel examples provided by immunotherapy of malignant gliomas.

Expert Rev Anticancer Ther 2011 Nov;11(11):1759-74

Fondazione I.R.C.C.S Istituto Neurologico C. Besta, Via Celoria 11, 20133 Milan, Italy.

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November 2011

Intra-tumoral dendritic cells increase efficacy of peripheral vaccination by modulation of glioma microenvironment.

Neuro Oncol 2010 Apr 6;12(4):377-88. Epub 2010 Jan 6.

Unit of Molecular Neuro-Oncology, Fondazione I.R.C.C.S. Istituto Neurologico C. Besta, 20133 Milan, Italy.

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April 2010

MGMT promoter hypermethylation in a series of 104 glioblastomas.

Cancer Genomics Proteomics 2009 Jul-Aug;6(4):219-27

Neuro-bio-oncology Center of Policlinico di Monza Foundation, University of Turin, Via Pietro Micca, 29 - 13100 Vercelli, Italy.

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December 2009

Reelin affects chain-migration and differentiation of neural precursor cells.

Mol Cell Neurosci 2009 Dec 19;42(4):341-9. Epub 2009 Aug 19.

Dept. of Experimental Medicine and Biochemical Sciences, University of Rome "Tor Vergata", 00133 Rome, Italy.

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December 2009

Dendritic cell vaccines for cancer stem cells.

Methods Mol Biol 2009 ;568:233-47

Unit of Experimental Neuro-Oncology, Fondazione IRCCS Istituto Neurologico Besta, Milano, Italy.

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November 2009

Genetic signature of adult gliomas and correlation with MRI features.

Expert Rev Mol Diagn 2009 Oct;9(7):709-20

Unit of Neuroradiology, Fondazione IRCCS Istituto Neurologico Besta, via Celoria 11, 20133 Milan, Italy.

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October 2009

High-resolution genomic copy number profiling of glioblastoma multiforme by single nucleotide polymorphism DNA microarray.

Mol Cancer Res 2009 May 12;7(5):665-77. Epub 2009 May 12.

Division of Hematology and Oncology, Cedars-Sinai Medical Center, University of California at Los Angeles School of Medicine, Davis Building 5022 Room, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA.

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May 2009

Radiation-induced glioblastoma in a medulloblastoma patient: a case report with molecular features.

Neuropathology 2008 Dec 1;28(6):633-9. Epub 2008 Apr 1.

Division of Neuropathology, Intituto Nazionale Neurologico C Besta, Milano, Italy.

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December 2008

Loss of heterozygosity studies in extracranial metastatic meningiomas.

J Neurooncol 2007 Oct 24;85(1):81-5. Epub 2007 Apr 24.

Department of Experimental Neurology and Diagnostics, Fondazione IRCCS Istituto Neurologico Besta, Milano, Italy.

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October 2007

Expression of the neurogenic basic helix-loop-helix transcription factor NEUROG1 identifies a subgroup of medulloblastomas not expressing ATOH1.

Neuro Oncol 2007 Jul 23;9(3):298-307. Epub 2007 May 23.

Unit of Experimental Neuro-Oncology, Carlo Besta Neurological Institute Foundation, via Celoria 11, 20133 Milan, Italy.

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July 2007

The therapeutic potential of neural stem/progenitor cells in murine globoid cell leukodystrophy is conditioned by macrophage/microglia activation.

Neurobiol Dis 2006 Feb 30;21(2):314-23. Epub 2005 Sep 30.

Istituto Nazionale Neurologico C. Besta, Department of Experimental Neuro-Oncology and Diagnostics, via Celoria 11, 20133 Milano, Italy.

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February 2006

Expression of MATH1, a marker of cerebellar granule cell progenitors, identifies different medulloblastoma sub-types.

Neurosci Lett 2004 Nov;370(2-3):180-5

Department of Experimental Neurosciences and Diagnostics, Unit of Experimental Neuro-Oncology and Gene Therapy, via Celoria 11, 20133 Milano, Italy.

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November 2004

Genetic alterations and in vivo tumorigenicity of neurospheres derived from an adult glioblastoma.

Mol Cancer 2004 Oct 6;3:25. Epub 2004 Oct 6.

Istituto Nazionale Neurologico Besta, Dept. Experimental Neurology, Milano, Italy.

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October 2004

The potential of stem cells for the treatment of brain tumors and globoid cell leukodystrophy.

Cytotechnology 2003 Mar;41(2-3):93-101

Istituto Nazionale Neurologico Besta, Unit of Neuro-Oncology and Gene Therapy, Milan, Italy (Author for correspondence).

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March 2003