Gaetano Donofrio

Gaetano Donofrio

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Gaetano Donofrio

Publications by authors named "Gaetano Donofrio"

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Molecular and Antigenic Properties of Mammalian Cell-Expressed Antigen Tp9.

Front Immunol 2019 29;10:897. Epub 2019 Apr 29.

Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, United States.

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http://dx.doi.org/10.3389/fimmu.2019.00897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501543PMC
April 2019

Fighting breast cancer stem cells through the immune-targeting of the xCT cystine-glutamate antiporter.

Cancer Immunol Immunother 2019 Jan 15;68(1):131-141. Epub 2018 Jun 15.

Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Turin, Via Nizza, 52, 10126, Turin, Italy.

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http://dx.doi.org/10.1007/s00262-018-2185-1DOI Listing
January 2019

Bovine herpesvirus 4-based vector delivering the full length xCT DNA efficiently protects mice from mammary cancer metastases by targeting cancer stem cells.

Oncoimmunology 2018 6;7(12):e1494108. Epub 2018 Sep 6.

Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, Università degli Studi di Torino, Torino, Italy.

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http://dx.doi.org/10.1080/2162402X.2018.1494108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279326PMC
September 2018

Bovine herpes virus type 4 alters TNF-α and IL-8 profiles and impairs the survival of bovine endometrial epithelial cells.

Reprod Biol 2017 Sep 22;17(3):225-232. Epub 2017 May 22.

Department of Clinical Sciences, Swedish University of Agricultural Sciences, SLU, PO Box 7054, 750 07 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.repbio.2017.05.006DOI Listing
September 2017

An IL-8 Transiently Transgenized Mouse Model for the In Vivo Long-term Monitoring of Inflammatory Responses.

J Vis Exp 2017 07 7(125). Epub 2017 Jul 7.

Department of Medicine, General Pathology Division, Cystic Fibrosis Translational Research Laboratory "D. Lissandrini", University of Verona;

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http://dx.doi.org/10.3791/55499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609320PMC
July 2017

Immunization of bighorn sheep against Mannheimia haemolytica with a bovine herpesvirus 1-vectored vaccine.

Vaccine 2017 03 20;35(12):1630-1636. Epub 2017 Feb 20.

Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0264410X173017
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http://dx.doi.org/10.1016/j.vaccine.2017.02.006DOI Listing
March 2017

Nonviral gene-delivery by highly fluorinated gemini bispyridinium surfactant-based DNA nanoparticles.

J Colloid Interface Sci 2017 Feb 15;487:182-191. Epub 2016 Oct 15.

Institut Charles Sadron (CNRS), University of Strasbourg, 23 rue du Loess, 67034 Strasbourg Cedex, France.

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http://dx.doi.org/10.1016/j.jcis.2016.10.032DOI Listing
February 2017

Interleukin 8 haplotypes drive divergent responses in uterine endometrial cells and are associated with somatic cell score in Holstein-Friesian cattle.

Vet Immunol Immunopathol 2017 Feb 16;184:18-28. Epub 2016 Dec 16.

Animal & Bioscience Research Department, Animal and Grassland Research and Innovation Centre, Teagasc, Grange, Dunsany, Co. Meath, Ireland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01652427163037
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http://dx.doi.org/10.1016/j.vetimm.2016.12.006DOI Listing
February 2017

BoHV-4-based vector delivering Ebola virus surface glycoprotein.

J Transl Med 2016 11 24;14(1):325. Epub 2016 Nov 24.

Department of Medical-Veterinary Science, University of Parma, Via del Taglio 10, 43126, Parma, Italy.

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http://dx.doi.org/10.1186/s12967-016-1084-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122150PMC
November 2016

A chimeric protein comprising the immunogenic domains of Mannheimia haemolytica leukotoxin and outer membrane protein PlpE induces antibodies against leukotoxin and PlpE.

Vet Immunol Immunopathol 2016 Jul 9;175:36-41. Epub 2016 May 9.

Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164-7040, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vetimm.2016.05.004DOI Listing
July 2016

Cyclodextrin- and calixarene-based polycationic amphiphiles as gene delivery systems: a structure-activity relationship study.

Org Biomol Chem 2015 Feb;13(6):1708-23

Dept. Química Orgánica, Facultad de Química, Universidad de Sevilla, c/Profesor García González 1, 41012 Sevilla, Spain.

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http://dx.doi.org/10.1039/c4ob02204aDOI Listing
February 2015

Nonviral gene delivery: gemini bispyridinium surfactant-based DNA nanoparticles.

J Phys Chem B 2014 Nov 10;118(46):13183-91. Epub 2014 Nov 10.

Department of Pharmacy, University of Parma , Parco Area delle Scienze 27/A, 43124 Parma, Italy.

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http://dx.doi.org/10.1021/jp507999gDOI Listing
November 2014

Enlightened Mannhemia haemolytica lung inflammation in bovinized mice.

Vet Res 2014 Jan 25;45. Epub 2014 Jan 25.

Department of Medical Veterinary Science, University of Parma, via del Taglio 10, 43126 Parma, Italy.

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http://dx.doi.org/10.1186/1297-9716-45-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906860PMC
January 2014

Aurora and IKK kinases cooperatively interact to protect multiple myeloma cells from Apo2L/TRAIL.

Blood 2013 Oct 23;122(15):2641-53. Epub 2013 Aug 23.

Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy;

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http://dx.doi.org/10.1182/blood-2013-02-482356DOI Listing
October 2013

Efficient heterologous antigen gene delivery and expression by a replication-attenuated BoHV-4-based vaccine vector.

Vaccine 2013 Aug 3;31(37):3906-14. Epub 2013 Jul 3.

Dipartimento di Scienze Medico-Veterinarie, Università di Parma, via del Taglio 10, 43126 Parma, Italy.

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http://dx.doi.org/10.1016/j.vaccine.2013.06.052DOI Listing
August 2013

Characterization of caprine herpesvirus 1 (CpHV1) glycoprotein E and glycoprotein I ectodomains expressed in mammalian cells.

Vet Microbiol 2013 Jun 22;164(3-4):222-8. Epub 2013 Feb 22.

Dipartimento di Produzioni Animali, Epidemiologia ed Ecologia, Università di Torino, Italy.

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http://dx.doi.org/10.1016/j.vetmic.2013.02.008DOI Listing
June 2013

Bovine endometrial stromal cells support tumor necrosis factor alpha-induced bovine herpesvirus type 4 enhanced replication.

Biol Reprod 2013 May 31;88(5):135. Epub 2013 May 31.

Department of Medical-Veterinary Science, University of Parma, Parma, Italy.

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http://dx.doi.org/10.1095/biolreprod.112.106740DOI Listing
May 2013

Bovine herpesvirus 4 glycoprotein B is indispensable for lytic replication and irreplaceable by VSVg.

BMC Vet Res 2013 Jan 9;9. Epub 2013 Jan 9.

Dipartimento di Scienze Medico Veterinarie, Università di Parma, via del Taglio 10, 43126, Parma, Italy.

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http://dx.doi.org/10.1186/1746-6148-9-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549454PMC
January 2013

Lower rim guanidinocalix[4]arenes: macrocyclic nonviral vectors for cell transfection.

Bioconjug Chem 2012 May 16;23(5):993-1002. Epub 2012 Apr 16.

Dipartimento di Chimica Organica e Industriale, Università di Parma , Parco Area delle Scienze 17/A, I-43124, Parma, Italy.

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http://dx.doi.org/10.1021/bc2006829DOI Listing
May 2012

Immunization of knock-out α/β interferon receptor mice against lethal bluetongue infection with a BoHV-4-based vector expressing BTV-8 VP2 antigen.

Vaccine 2011 Apr 12;29(16):3074-82. Epub 2011 Feb 12.

Dipartimento di Salute Animale, Facoltà di Medicina Veterinaria, Università di Parma, via del Taglio 10, 43100 Parma, Italy.

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http://dx.doi.org/10.1016/j.vaccine.2011.01.075DOI Listing
April 2011

Bovine herpesvirus 4 immediate early 2 (Rta) gene is an essential gene and is duplicated in bovine herpesvirus 4 isolate U.

Vet Microbiol 2011 Mar 7;148(2-4):219-31. Epub 2010 Oct 7.

Dipartimento di Salute Animale, Facoltà di Medicina Veterinaria, Università di Parma, via del Taglio 10, 43100 Parma, Italy.

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http://dx.doi.org/10.1016/j.vetmic.2010.09.031DOI Listing
March 2011

Swine adipose stromal cells loaded with recombinant bovine herpesvirus 4 virions expressing a foreign antigen induce potent humoral immune responses in pigs.

Vaccine 2011 Jan 27;29(5):867-72. Epub 2010 Nov 27.

Dipartimento di Salute Animale, Università di Parma, Sezione di Malattie Infettive degli Animali, Via del Taglio 10, 43126 Parma, Italy.

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http://dx.doi.org/10.1016/j.vaccine.2010.11.048DOI Listing
January 2011

The chemokine IL8 is up-regulated in bovine endometrial stromal cells by the BoHV-4 IE2 gene product, ORF50/Rta: a step ahead toward a mechanism for BoHV-4 induced endometritis.

Biol Reprod 2010 Dec 18;83(6):919-28. Epub 2010 Aug 18.

Sezione di Malattie Infettive degli Animali, Dipartimento di Salute Animale, Facoltà di Medicina Veterinaria, Università di Parma, Parma, Italy.

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http://dx.doi.org/10.1095/biolreprod.110.086074DOI Listing
December 2010

Integration of bovine herpesvirus 4 genome into cultured persistently infected host cell genome.

Virol J 2010 Sep 21;7:246. Epub 2010 Sep 21.

Dipartimento di Salute Animale, Sezione di Malattie Infettive degli Animali, Università di Parma, Via del Taglio 10, 43100 Parma, Italy.

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http://dx.doi.org/10.1186/1743-422X-7-246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949847PMC
September 2010

Virally and physically transgenized equine adipose-derived stromal cells as a cargo for paracrine secreted factors.

BMC Cell Biol 2010 Sep 23;11:73. Epub 2010 Sep 23.

Dipartimento di Salute Animale, Sezione di Malattie Infettive, Facoltà di Medicina Veterinaria, via del Taglio 10, 43100 Parma, Italy.

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http://dx.doi.org/10.1186/1471-2121-11-73DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949624PMC
September 2010

Defining postpartum uterine disease and the mechanisms of infection and immunity in the female reproductive tract in cattle.

Biol Reprod 2009 Dec 13;81(6):1025-32. Epub 2009 May 13.

Institute of Life Science, School of Medicine, Swansea University, Swansea, UK.

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http://dx.doi.org/10.1095/biolreprod.109.077370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784443PMC
December 2009

Isolation and characterization of bovine herpesvirus 4 (BoHV-4) from a cow affected by post partum metritis and cloning of the genome as a bacterial artificial chromosome.

Reprod Biol Endocrinol 2009 Aug 19;7:83. Epub 2009 Aug 19.

Dipartimento di Salute Animale, Facoltà di Medicina Veterinaria, Università di Parma, via del Taglio 10, 43100 Parma, Italy.

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http://dx.doi.org/10.1186/1477-7827-7-83DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734843PMC
August 2009

Bovine endometrial stromal cells display osteogenic properties.

Reprod Biol Endocrinol 2008 Dec 16;6:65. Epub 2008 Dec 16.

Università di Parma, Facoltà di Medicina Veterinaria, Dipartimento di Salute Animale, Sezione di Malattie Infettive degli Animali, Via del Taglio 8, 43100 Parma, Italy.

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http://dx.doi.org/10.1186/1477-7827-6-65DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657796PMC
December 2008

Bacterial infection of endometrial stromal cells influences bovine herpesvirus 4 immediate early gene activation: a new insight into bacterial and viral interaction for uterine disease.

Reproduction 2008 Sep 24;136(3):361-6. Epub 2008 Jun 24.

Dipartimento di Salute Animale, Facoltà di Medicina Veterinaria, Università di Parma, Sezione di Malattie Infettive degli Animali, via del Taglio 8, 43100 Parma, Italy.

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http://dx.doi.org/10.1530/REP-08-0171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707594PMC
September 2008

Macrocyclic nonviral vectors: high cell transfection efficiency and low toxicity in a lower rim guanidinium calix[4]arene.

Org Lett 2008 Sep 23;10(18):3953-6. Epub 2008 Aug 23.

Dipartimento di Chimica Organica e Industriale, Università di Parma, V.le G. P. Usberti 17/a, 43100 Parma, Italy.

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http://dx.doi.org/10.1021/ol801326dDOI Listing
September 2008

Thermodynamics and biological properties of the aqueous solutions of new glucocationic surfactants.

J Phys Chem B 2008 Aug 11;112(31):9360-70. Epub 2008 Jul 11.

Dipartimento di Scienze Farmacologiche, Biologiche e Chimiche Applicate, Università di Parma, Viale G.P. Usberti, 27/A-43100 Parma, Italy.

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http://dx.doi.org/10.1021/jp800470aDOI Listing
August 2008

Assessment of bovine herpesvirus 4 based vector in chicken.

J Virol Methods 2008 Mar;148(1-2):303-6

Dipartimento di Salute Animale, Sezione di Malattie Infettive degli Animali, Facoltà di Medicina Veterinaria, 43100 Parma, Italy.

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http://dx.doi.org/10.1016/j.jviromet.2007.12.006DOI Listing
March 2008

Transduction of the rat brain by Bovine Herpesvirus 4.

Genet Vaccines Ther 2008 Feb 12;6. Epub 2008 Feb 12.

Department of Human Anatomy and Physiology, University of Padova, 35131 Padova, Italy.

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http://dx.doi.org/10.1186/1479-0556-6-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2259350PMC
February 2008

Establishment of a bovine herpesvirus 4 based vector expressing a secreted form of the bovine viral diarrhoea virus structural glycoprotein E2 for immunization purposes.

BMC Biotechnol 2007 Oct 18;7:68. Epub 2007 Oct 18.

Università di Parma, Facoltà di Medicina Veterinaria, Dipartimento di Salute Animale, Sezione di Malattie Infettive degli Animali, via del Taglio 8, 43100 Parma, Italy.

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http://dx.doi.org/10.1186/1472-6750-7-68DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048506PMC
October 2007

Production of Wnt inhibitors by myeloma cells: potential effects on canonical Wnt pathway in the bone microenvironment.

Cancer Res 2007 Aug;67(16):7665-74

Hematology and Bone Marrow Transplantation Center, Department of Internal Medicine and Biomedical Science, University of Parma, Parma, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-4666DOI Listing
August 2007

Bovine herpesvirus 4 is tropic for bovine endometrial cells and modulates endocrine function.

Reproduction 2007 Jul;134(1):183-97

Dipartimento di Salute Animale, Sezione di Malattie Infettive, Facoltà di Medicina Veterinaria, via del Taglio 8, 43100 Parma, Italy.

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http://dx.doi.org/10.1530/REP-07-0065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2740819PMC
July 2007

Generation of a transposon insertion mutant library for bovine herpesvirus 4 cloned as a bacterial artificial chromosome by in vitro MuA based DNA transposition system.

J Virol Methods 2007 Apr 19;141(1):63-70. Epub 2006 Dec 19.

Università di Parma, Facoltà di Medicina Veterinaria, Dipartimento di Salute Animale, Sezione di Malattie Infettive degli Animali, via del Taglio 8, 43100 Parma, Italy.

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http://dx.doi.org/10.1016/j.jviromet.2006.11.028DOI Listing
April 2007

First Serbian isolates of bovine herpesvirus 4 (BoHV-4) from a herd with a history of postpartum metritis.

New Microbiol 2007 Jan;30(1):53-7

Department of Virology, The Institute of Veterinary Medicine of Serbia, Belgrade, Belgrade, Serbia.

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http://www.newmicrobiologica.org/pub/allegati_pdf/2007/1/53.
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January 2007

Recombinant bovine herpesvirus 4 (BoHV-4) expressing glycoprotein D of BoHV-1 is immunogenic and elicits serum-neutralizing antibodies against BoHV-1 in a rabbit model.

Clin Vaccine Immunol 2006 Nov 23;13(11):1246-54. Epub 2006 Aug 23.

Dipartimento di Salute Animale, Sezione di Malattie Infettive, Facoltà di Medicina Veterinaria, via del Taglio 8, 43100 Parma, Italy.

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http://dx.doi.org/10.1128/CVI.00200-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1656551PMC
November 2006

DNA condensation and cell transfection properties of guanidinium calixarenes: dependence on macrocycle lipophilicity, size, and conformation.

J Am Chem Soc 2006 Nov;128(45):14528-36

Dipartimento di Chimica Organica e Industriale, Università degli Studi, Viale G. P. Usberti 17/A, 43100 Parma, Italy.

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http://pubs.acs.org/doi/abs/10.1021/ja0634425
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http://dx.doi.org/10.1021/ja0634425DOI Listing
November 2006

Bovine herpesvirus 4 based vector interaction with liver cells in vitro and in vivo.

J Virol Methods 2006 Sep 19;136(1-2):126-36. Epub 2006 May 19.

Dipartimento di Salute Animale, Facoltà di Medicina Veterinaria, Sezione di Malattie Infettive degli Animali, Università di Parma, via del Taglio 8, 43100 Parma, Italy.

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http://dx.doi.org/10.1016/j.jviromet.2006.04.008DOI Listing
September 2006

Association between Coxiella burnetii seropositivity and abortion in dairy cattle of Northern Italy.

New Microbiol 2006 Jul;29(3):211-4

Università di Parma, Dipartimento di Salute Animale, Parma, Italy.

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July 2006

Expression of bovine viral diarrhea virus glycoprotein E2 as a soluble secreted form in a Mammalian cell line.

Clin Vaccine Immunol 2006 Jun;13(6):698-701

Dipartimento di Salute Animale, Sezione di Malattie Infettive degli Animali, Facoltà di Medicina Veterinaria, Via del Taglio 8, 43100 Parma, Italy.

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http://dx.doi.org/10.1128/CVI.00071-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1489545PMC
June 2006

Outcome of bovine herpesvirus 4 infection following direct viral injection in the lateral ventricle of the mouse brain.

Microbes Infect 2006 Mar 3;8(3):898-904. Epub 2006 Feb 3.

Dipartimento di Salute Animale, Sezione di Malattie Infettive degli Animali, Università di Parma, Via del Taglio 8, 43100 Parma, Italy.

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http://dx.doi.org/10.1016/j.micinf.2005.10.016DOI Listing
March 2006

Paracrine inhibition of prion propagation by anti-PrP single-chain Fv miniantibodies.

J Virol 2005 Jul;79(13):8330-8

Institute of Neuropathology, University Hospital Zurich, Schmelzbergstrasse 12, CH-8091 Zürich, Switzerland.

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http://dx.doi.org/10.1128/JVI.79.13.8330-8338.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1143714PMC
July 2005

Potential secondary pathogenic role for bovine herpesvirus 4.

J Clin Microbiol 2005 Jul;43(7):3421-6

Dipartimento di Salute Animale, Sezione di Malattie Infettive degli Animali, Facoltà di Medicina Veterinaria, via del Taglio 8, 43100 Parma, Italy.

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http://dx.doi.org/10.1128/JCM.43.7.3421-3426.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1169148PMC
July 2005

Biologically active bisquaternary ammonium chlorides: physico-chemical properties of long chain amphiphiles and their evaluation as non-viral vectors for gene delivery.

Biochim Biophys Acta 2005 Mar 19;1722(2):224-33. Epub 2005 Jan 19.

Dipartimento di Scienze Farmacologiche, Biologiche e Chimiche Applicate, Università di Parma, Parco Area delle Scienze, 27A-43100 Parma, Italy.

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http://dx.doi.org/10.1016/j.bbagen.2004.12.013DOI Listing
March 2005

Bovine herpesvirus 4 infects differentiated neuronal cells in culture and establish persistent infection upon selection.

J Neurovirol 2004 Apr;10(2):123-30

Sezione di Malattie Infettive degli Animali, Dipartimento di Salute Animale, Parma, Italy.

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http://dx.doi.org/10.1080/13550280490279780DOI Listing
April 2004

Activation of bovine herpesvirus 4 lytic replication in a non-permissive cell line by overexpression of BoHV-4 immediate early (IE) 2 gene.

J Virol Methods 2004 Mar;116(2):203-7

Sezione di Malattie Infettive degli Animali, Dipartimento di Salute Animale, via del Taglio 8, Parma 43100, Italy.

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http://dx.doi.org/10.1016/j.jviromet.2003.11.019DOI Listing
March 2004

Potential of bovine herpesvirus 4 as a gene delivery vector.

J Virol Methods 2002 Mar;101(1-2):49-61

Facolta' di Medicina Veterinaria, Sezione di Malattie Infettive degli Animali, Dipartimento di Salute Animale, Universita' degli Studi di Parma, Via del Taglio 8, 43100, Parma, Italy.

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http://dx.doi.org/10.1016/s0166-0934(01)00419-0DOI Listing
March 2002