Publications by authors named "Gabrielle A Mesches"

2 Publications

  • Page 1 of 1

Treatment Integrity Failures during Timeout from Play.

Behav Modif 2020 Jun 16:145445520935392. Epub 2020 Jun 16.

West Virginia University, Morgantown, WV, USA.

Timeout is an effective behavior-reduction strategy with considerable generality. However, little is known about how timeout is implemented under natural conditions, or how errors in implementation impact effectiveness. During Experiment 1, we observed teachers implementing timeout during play to evaluate how frequently the teachers implemented timeout following target behavior (omission errors) and other behaviors (commission errors) for four children. Teachers rarely implemented timeout; thus, omission errors were frequent, but commission errors rarely occurred. During Experiment 2, we used a reversal design to compare timeout implemented with 0% omission integrity, 100% integrity, and the level of omission integrity observed to occur during Experiment 1 for two of the participants. Timeout implemented with reduced-integrity decreased problem behavior relative to baseline, suggesting that infrequent teacher implementation of timeout may have been sufficient to reduce problem behavior.
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http://dx.doi.org/10.1177/0145445520935392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738358PMC
June 2020

A common clinical conundrum: Antidepressant treatment of depression in pregnant women.

Semin Perinatol 2020 04 25;44(3):151229. Epub 2020 Jan 25.

Mayo Clinic, Rochester, MN, United States.

Depression during pregnancy is associated with adverse maternal, pregnancy, and infant outcomes. Treatment during pregnancy requires a balanced discussion of the risks of both drug exposure and untreated depression. An updated review of the epidemiology, outcomes, and management of maternal depression is presented. Adverse outcomes are associated with both maternal depression and antidepressants. Research gaps include data on the longitudinal developmental trajectory of offspring exposed to antidepressants compared to depression, with assessment of in utero symptom exposure and environmental exposures. Additionally, neonatal syndrome associated with antidepressant use during pregnancy has no consensus definition or mechanistic explanation. With sophisticated large-scale epidemiologic studies, there has been progress in distinguishing the impact of depression processes from medication used for treatment. Optimal treatment of perinatal depression includes close symptom monitoring and medication adjustments to maintain symptom remission. This evolving field requires frequent consultation with reproductive data sources included in this article.
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http://dx.doi.org/10.1016/j.semperi.2020.151229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214132PMC
April 2020