Gabriele Stocco

Gabriele Stocco

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Gabriele Stocco

Publications by authors named "Gabriele Stocco"

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Therapeutic drug monitoring to improve outcome of anti-TNF drugs in pediatric inflammatory bowel disease.

Expert Opin Drug Metab Toxicol 2019 Jul 14;15(7):527-539. Epub 2019 Jun 14.

e University of Trieste , Department of Life Sciences , Trieste , Italy.

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http://dx.doi.org/10.1080/17425255.2019.1630378DOI Listing
July 2019

Perspectives on Rational Drug Design and Therapy for Pediatric Precision Medicine.

Authors:
Gabriele Stocco

Curr Med Chem 2018;25(24):2762-2763

Department of Life Sciences University of Trieste Via Fleming 22 34127 Trieste, Italy.

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http://dx.doi.org/10.2174/092986732524180704125041DOI Listing
December 2018

Pharmacogenetics of treatments for inflammatory bowel disease.

Expert Opin Drug Metab Toxicol 2018 Dec 3;14(12):1209-1223. Epub 2018 Dec 3.

e Department of Life Sciences , University of Trieste , Trieste , Italy.

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http://dx.doi.org/10.1080/17425255.2018.1551876DOI Listing
December 2018

Novel motif of variable number of tandem repeats in TPMT promoter region and evolutionary association of variable number of tandem repeats with TPMT*3 alleles.

Pharmacogenomics 2018 11 22;19(17):1311-1322. Epub 2018 Oct 22.

Department of Clinical Biochemistry, Faculty of Pharmacy, University of Ljubljana, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia.

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https://www.futuremedicine.com/doi/10.2217/pgs-2018-0123
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http://dx.doi.org/10.2217/pgs-2018-0123DOI Listing
November 2018

How to predict response to anti-tumour necrosis factor agents in inflammatory bowel disease.

Expert Rev Gastroenterol Hepatol 2018 Aug 6;12(8):797-810. Epub 2018 Jul 6.

c First Department of Internal Medicine, San Matteo Hospital Foundation , University of Pavia , Pavia , Italy.

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http://dx.doi.org/10.1080/17474124.2018.1494573DOI Listing
August 2018

Risk Factors and Outcomes of Thalidomide-induced Peripheral Neuropathy in a Pediatric Inflammatory Bowel Disease Cohort.

Inflamm Bowel Dis 2017 10;23(10):1810-1816

*Pediatric Gastroenterology, Institute for Maternal and Child Health, IRCCS "Burlo Garofolo," Trieste, Italy; †Department of Life Sciences, University of Trieste, Trieste, Italy; ‡Clinical Epidemiology and Public Health Research Unit, Institute for Maternal and Child Health, IRCCS "Burlo Garofolo," Trieste, Italy; §Pediatric Gastroenterology Unit, Institute "Giannina Gaslini," Genoa, Italy; ‖Neuropsychiatry Unit, Institute "Giannina Gaslini," Genoa, Italy; ¶Pediatric Gastroenterology and Cystic Fibrosis Unit, University of Messina, Messina, Italy; **Department of Sciences for Woman and Child Health, University of Florence, Meyer Children Hospital, Florence, Italy; ††Pediatric Department, Children's Hospital "V. Buzzi" Milan, Italy; ‡‡Pediatric Gastroenterology and Hepatology, University of Pisa, Pisa, Italy; §§Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy; and ‖‖Pediatric Neurology, Institute for Maternal and Child Health, IRCCS "Burlo Garofolo," Trieste, Italy.

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http://dx.doi.org/10.1097/MIB.0000000000001195DOI Listing
October 2017

Glucocorticoid Receptor Interacting Co-regulators: Putative Candidates for Future Drug Targeting Therapy.

Mini Rev Med Chem 2017 ;17(8):657-666

Department of Life Sciences, University of Trieste, Via Alexander Fleming, 22, 34127 Trieste, Italy.

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http://dx.doi.org/10.2174/1389557516666161130094255DOI Listing
September 2017

Pharmacokinetics and pharmacodynamics of thiopurines in an in vitro model of human hepatocytes: Insights from an innovative mass spectrometry assay.

Chem Biol Interact 2017 Sep 12;275:189-195. Epub 2017 Aug 12.

Department of Medical, Surgical and Health Sciences, University of Trieste, I-34127 Trieste, Italy; Institute for Maternal and Child Health I.R.C.C.S. Burlo Garofolo, I-34137 Trieste, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S00092797173025
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http://dx.doi.org/10.1016/j.cbi.2017.08.009DOI Listing
September 2017

Multicentric Case-Control Study on Azathioprine Dose and Pharmacokinetics in Early-onset Pediatric Inflammatory Bowel Disease.

Inflamm Bowel Dis 2017 04;23(4):628-634

*Department of Life Sciences, University of Trieste, Trieste, Italy; †Department of Pediatrics, Institute for Maternal and Child Health Burlo Garofolo, Trieste, Italy; ‡Gastroenterology and Endoscopy Unit, Gaslini Institute for Children, Genoa, Italy; §Pediatric Gastroenterology and Liver Unit, Sapienza University of Rome, Rome, Italy; ‖Department of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, Naples, Italy; ¶Hepatology, Gastroenterology and Nutrition Unit, Bambino Gesù Children's Hospital, Rome, Italy; **Department of Pediatric, University of Messina, Messina, Italy; ††PhD School in Science of Reproduction and Development, University of Trieste, Trieste, Italy; and ‡‡Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.

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http://dx.doi.org/10.1097/MIB.0000000000001051DOI Listing
April 2017

Thiopurine Biotransformation and Pharmacological Effects: Contribution of Oxidative Stress.

Curr Drug Metab 2016 ;17(6):542-9

University of Trieste, Department of Life Sciences, Via A. Fleming 22, Trieste, I-34127, Italy.

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February 2017

Glucocorticoid pharmacogenetics in pediatric idiopathic nephrotic syndrome.

Pharmacogenomics 2015 30;16(14):1631-48. Epub 2015 Sep 30.

Department of Life Sciences, University of Trieste, I-34127 Trieste, Italy.

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http://dx.doi.org/10.2217/pgs.15.101DOI Listing
July 2016

Carbamazepine-induced thrombocytopenic purpura in a child: Insights from a genomic analysis.

Blood Cells Mol Dis 2016 07 3;59:97-9. Epub 2016 May 3.

Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy; Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy.

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http://dx.doi.org/10.1016/j.bcmd.2016.05.001DOI Listing
July 2016

Role of Pharmacogenetics in Hematopoietic Stem Cell Transplantation Outcome in Children.

Int J Mol Sci 2015 Aug 10;16(8):18601-27. Epub 2015 Aug 10.

Institute for Maternal and Child Health (I.R.C.C.S.) Burlo Garofolo, UO Pediatric Hemato-Oncology, Trieste 34137, Italy.

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http://dx.doi.org/10.3390/ijms160818601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581262PMC
August 2015

Role of oxidative stress mediated by glutathione-s-transferase in thiopurines' toxic effects.

Chem Res Toxicol 2015 Jun 8;28(6):1186-95. Epub 2015 May 8.

†Department of Life Sciences, University of Trieste, 34127 Trieste, Italy.

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http://dx.doi.org/10.1021/acs.chemrestox.5b00019DOI Listing
June 2015

Genetic determinants for methotrexate response in juvenile idiopathic arthritis.

Front Pharmacol 2015 23;6:52. Epub 2015 Mar 23.

Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste Italy ; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste Italy.

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http://dx.doi.org/10.3389/fphar.2015.00052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369651PMC
April 2015

Pharmacogenetics of azathioprine in inflammatory bowel disease: a role for glutathione-S-transferase?

World J Gastroenterol 2014 Apr;20(13):3534-41

Gabriele Stocco, Marco Pelin, Giuliana Decorti, Department of Life Sciences, University of Trieste, I-34127 Trieste, Italy.

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http://dx.doi.org/10.3748/wjg.v20.i13.3534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974520PMC
April 2014

Deletion of glutathione-s-transferase m1 reduces azathioprine metabolite concentrations in young patients with inflammatory bowel disease.

J Clin Gastroenterol 2014 Jan;48(1):43-51

Departments of *Life Sciences †Medical, Surgical, and Health Sciences ∥Scuola di Dottorato di Ricerca in Scienze della Riproduzione, University of Trieste ‡Institute for Maternal and Child Health IRCCS Burlo Garofolo §Department of Prevention, Sanitary Services Agency Number 1, Trieste, Italy.

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http://dx.doi.org/10.1097/MCG.0b013e31828b2866DOI Listing
January 2014

ABCB1 and ABCC1 variants associated with virological failure of first-line protease inhibitors antiretroviral regimens in Northeast Brazil patients.

J Clin Pharmacol 2013 Dec 17;53(12):1286-93. Epub 2013 Sep 17.

Department of Genetics, Federal University of Pernambuco, Recife, PE, Brazil; Laboratory of Immunopatology Keizo Asami (LIKA), Federal University of Pernambuco, Recife, PE, Brazil.

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http://dx.doi.org/10.1002/jcph.165DOI Listing
December 2013

Commentary.

Authors:
Gabriele Stocco

Clin Chem 2013 Jul;59(7):1027

Department of Life Sciences, University of Trieste, Trieste, Italy.

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http://dx.doi.org/10.1373/clinchem.2012.200428DOI Listing
July 2013

Personalized therapies in pediatric inflammatory and autoimmune diseases.

Curr Pharm Des 2012 ;18(35):5766-75

Department of Life Sciences, University of Trieste, Trieste, 34127 TS, Italy.

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http://dx.doi.org/10.2174/138161212803530853DOI Listing
May 2013

Effect of periodontal therapy on the course of cyclosporin-induced gingival overgrowth: role of ABCB1 and PAI-1 gene polymorphisms.

Quintessence Int 2013 Mar;44(3):249-60

Dipartimento Universitario Clinico di Scienze Mediche, Chirurgiche e della Salute, University of Trieste, Trieste, Italy.

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http://dx.doi.org/10.3290/j.qi.a29052DOI Listing
March 2013

Systematic identification of host genomic variation related to treatment outcome of childhood acute lymphoblastic leukemia.

Pharmacogenomics 2013 Feb;14(3):235-6

Department of Life Sciences, University of Trieste, Trieste, Italy.

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http://dx.doi.org/10.2217/pgs.13.5DOI Listing
February 2013

Processes for incorporation of pharmacogenetic tests and interpretations in medical records for clinical practice.

Pharmacogenomics 2013 Feb;14(3):236-7

Department of Life Sciences, University of Trieste, Trieste, Italy.

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February 2013

ITPA genetic polymorphism is possibly associated with survival rate in Korean children with acute lymphoblastic leukemia.

Pharmacogenomics 2013 Feb;14(3):237-8

Department of Life Sciences, University of Trieste, Trieste, Italy.

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February 2013

DMET™ Plus array delivers results in good concordance with those of several lower-throughput genotyping methods in patient samples.

Pharmacogenomics 2013 Feb;14(3):238-9

Department of Life Sciences, University of Trieste, Trieste, Italy.

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February 2013

Pharmacogenomics in pediatric leukemia.

Curr Opin Pediatr 2010 Dec;22(6):703-10

Hematological Malignancies Program and Department of Pharmaceutical Sciences, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1097/MOP.0b013e32833fde85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612020PMC
December 2010

Genetic polymorphism of inosine-triphosphate-pyrophosphatase influences mercaptopurine metabolism and toxicity during treatment of acute lymphoblastic leukemia individualized for thiopurine-S-methyl-transferase status.

Expert Opin Drug Saf 2010 Jan;9(1):23-37

St. Jude Children's Research Hospital, Department of Pharmaceutical Sciences, 262 Danny Thomas Place MS 272, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1517/14740330903426151DOI Listing
January 2010

Carbamazepine hypersensitivity syndrome triggered by a human herpes virus reactivation in a genetically predisposed patient.

Int Arch Allergy Immunol 2009 6;149(2):173-7. Epub 2009 Jan 6.

IRCCS Burlo Garofolo, Pediatric Clinic, University of Trieste, Trieste IT-34127, Italy.

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http://dx.doi.org/10.1159/000189202DOI Listing
June 2009

ABCB1 gene polymorphisms and expression of P-glycoprotein and long-term prognosis in colorectal cancer.

Anticancer Res 2008 Nov-Dec;28(6B):3921-8

Department of Life Sciences, University of Trieste, Italy.

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February 2009

Interruption of mesalamine and reduction of the blood concentration of the active metabolites of azathioprine: possible causes of ulcerative colitis relapse.

Dig Dis Sci 2008 Dec 10;53(12):3246-9. Epub 2008 May 10.

Department of Biomedical Sciences, University of Trieste, Via L.Giorgieri 7,9, 34127, Trieste, Italy.

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http://link.springer.com/10.1007/s10620-008-0283-1
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http://dx.doi.org/10.1007/s10620-008-0283-1DOI Listing
December 2008

Distinct effects of dinuclear ruthenium(III) complexes on cell proliferation and on cell cycle regulation in human and murine tumor cell lines.

J Pharmacol Exp Ther 2003 May 11;305(2):725-32. Epub 2003 Feb 11.

Foundation Callerio-Onlus, Laboratories for Biological Research, Via A. Fleming 22-31, 34127 Trieste, Italy.

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http://dx.doi.org/10.1124/jpet.102.047803DOI Listing
May 2003