Publications by authors named "Gabriel Santpere"

41Publications

The Presence of Human Herpesvirus 6 in the Brain in Health and Disease.

Biomolecules 2020 Nov 6;10(11). Epub 2020 Nov 6.

Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), 28031 Madrid, Spain.

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http://dx.doi.org/10.3390/biom10111520DOI Listing
November 2020

Expanding the Geographic Characterisation of Epstein-Barr Virus Variation through Gene-Based Approaches.

Microorganisms 2020 Oct 29;8(11). Epub 2020 Oct 29.

Neurogenomics Group, Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Medical Research Institute (IMIM), Department of Experimental and Health Sciences (DXECS), Universitat Pompeu Fabra, 08003 Barcelona, Spain.

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http://dx.doi.org/10.3390/microorganisms8111686DOI Listing
October 2020

Whole-Genome and RNA Sequencing Reveal Variation and Transcriptomic Coordination in the Developing Human Prefrontal Cortex.

Cell Rep 2020 04;31(1):107489

Department of Neuroscience and Kavli Institute for Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA; Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06520, USA; Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA; Department of Comparative Medicine, Program in Integrative Cell Signaling and Neurobiology of Metabolism, Yale School of Medicine, New Haven, CT 06510, USA; Program in Cellular Neuroscience, Neurodegeneration, and Repair and Yale Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.03.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295160PMC
April 2020

Modeling the Evolution of Human Brain Development Using Organoids.

Cell 2019 11;179(6):1250-1253

Departments of Genetics, Psychiatry, and Comparative Medicine, Program in Cellular Neuroscience, Neurodegeneration and Repair, and Yale Child Study Center, Yale School of Medicine, New Haven, CT, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.10.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034679PMC
November 2019

Gene Expression Profile in Frontal Cortex in Sporadic Frontotemporal Lobar Degeneration-TDP.

J Neuropathol Exp Neurol 2018 07;77(7):608-627

Neuropathology, Pathologic Anatomy Service, Bellvitge University Hospital, IDIBELL, Hospitalet de Llobregat, Spain.

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http://dx.doi.org/10.1093/jnen/nly037DOI Listing
July 2018

Author Correction: Whole genome diversity of inherited chromosomally integrated HHV-6 derived from healthy individuals of diverse geographic origin.

Sci Rep 2018 Apr 17;8(1):6357. Epub 2018 Apr 17.

Institute of Evolutionary Biology (UPF-CSIC), Departament de Ciències Experimentals i la Salut, Universitat Pompeu Fabra, PRBB, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1038/s41598-018-24603-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902477PMC
April 2018

Whole genome diversity of inherited chromosomally integrated HHV-6 derived from healthy individuals of diverse geographic origin.

Sci Rep 2018 02 22;8(1):3472. Epub 2018 Feb 22.

Institute of Evolutionary Biology (UPF-CSIC), Departament de Ciències Experimentals i la Salut, Universitat Pompeu Fabra, PRBB, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1038/s41598-018-21645-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823862PMC
February 2018

Transcriptome evolution from breast epithelial cells to basal-like tumors.

Oncotarget 2018 Jan 8;9(1):453-463. Epub 2017 Dec 8.

Translational Research Unit and CIBERONC, Albacete University Hospital, Albacete, Spain.

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http://dx.doi.org/10.18632/oncotarget.23065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787480PMC
January 2018

Functional transcriptomic annotation and protein-protein interaction network analysis identify NEK2, BIRC5, and TOP2A as potential targets in obese patients with luminal A breast cancer.

Breast Cancer Res Treat 2018 Apr 12;168(3):613-623. Epub 2018 Jan 12.

Translational Oncology Laboratory, Centro Regional de Investigaciones Biomédicas (CRIB), Universidad de Castilla La Mancha (UCLM), C/Almansa 14, 02008, Albacete, Spain.

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http://dx.doi.org/10.1007/s10549-017-4652-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842257PMC
April 2018

Evolution of the Human Nervous System Function, Structure, and Development.

Cell 2017 Jul;170(2):226-247

Department of Neuroscience, Yale School of Medicine, New Haven, CT, USA; Department of Genetics, Yale School of Medicine, New Haven, CT, USA; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA; Section of Comparative Medicine, Yale School of Medicine, New Haven, CT, USA; Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale School of Medicine, New Haven, CT, USA; Yale Child Study Center, Yale School of Medicine, New Haven, CT, USA; Kavli Institute for Neuroscience, Yale School of Medicine, New Haven, CT, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.06.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647789PMC
July 2017

Genetic factors affecting EBV copy number in lymphoblastoid cell lines derived from the 1000 Genome Project samples.

PLoS One 2017 27;12(6):e0179446. Epub 2017 Jun 27.

Institute of Evolutionary Biology (UPF-CSIC), Departament de Ciències Experimentals i la Salut, Universitat Pompeu Fabra, PRBB, Barcelona, Catalonia, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0179446PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487016PMC
September 2017

Erratum to: Interhemispheric gene expression differences in the cerebral cortex of humans and macaque monkeys.

Brain Struct Funct 2017 09;222(7):3367-3368

Department of Anthropology and Center for the Advanced Study of Human Paleobiology, The George Washington University, Washington, DC, 20052, USA.

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http://dx.doi.org/10.1007/s00429-017-1433-zDOI Listing
September 2017

Transcriptional network analysis in frontal cortex in Lewy body diseases with focus on dementia with Lewy bodies.

Brain Pathol 2018 05 6;28(3):315-333. Epub 2017 Apr 6.

Department of Pathology and Experimental Therapeutics, University of Barcelona, L'Hospitalet de Llobregat, Spain.

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http://dx.doi.org/10.1111/bpa.12511DOI Listing
May 2018

Interhemispheric gene expression differences in the cerebral cortex of humans and macaque monkeys.

Brain Struct Funct 2017 Sep 19;222(7):3241-3254. Epub 2017 Mar 19.

Department of Anthropology and Center for the Advanced Study of Human Paleobiology, The George Washington University, Washington, DC, 20052, USA.

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http://dx.doi.org/10.1007/s00429-017-1401-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605391PMC
September 2017

Natural Selection in the Great Apes.

Mol Biol Evol 2016 12 30;33(12):3268-3283. Epub 2016 Oct 30.

Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.

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http://dx.doi.org/10.1093/molbev/msw215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100057PMC
December 2016

Differences in molecular evolutionary rates among microRNAs in the human and chimpanzee genomes.

BMC Genomics 2016 07 29;17:528. Epub 2016 Jul 29.

Department of Experimental and Health Sciences, IBE, Institute of Evolutionary Biology, (Universitat Pompeu Fabra -CSIC), Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1186/s12864-016-2863-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966751PMC
July 2016

Great ape genetic diversity and population history.

Nature 2013 Jul 3;499(7459):471-5. Epub 2013 Jul 3.

Institut de Biologia Evolutiva, CSIC-Universitat Pompeu Fabra, PRBB, Doctor Aiguader 88, Barcelona, Catalonia 08003, Spain.

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http://dx.doi.org/10.1038/nature12228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822165PMC
July 2013

Enhanced Botrytis cinerea resistance of Arabidopsis plants grown in compost may be explained by increased expression of defense-related genes, as revealed by microarray analysis.

PLoS One 2013 6;8(2):e56075. Epub 2013 Feb 6.

Unitat de Fisiologia Vegetal, Departament de Biologia Vegetal, Facultat de Biologia, Universitat de Barcelona, Barcelona, Catalonia, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0056075PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566078PMC
August 2013

Evidence for premature lipid raft aging in APP/PS1 double-transgenic mice, a model of familial Alzheimer disease.

J Neuropathol Exp Neurol 2012 Oct;71(10):868-81

Laboratorio de Fisiología y Biofísica de Membranas, Facultad de Biología, Universidad de La Laguna, Tenerife, Spain.

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http://dx.doi.org/10.1097/NEN.0b013e31826be03cDOI Listing
October 2012

Lipid alterations in lipid rafts from Alzheimer's disease human brain cortex.

J Alzheimers Dis 2010 ;19(2):489-502

Instituto de Tecnologías Biomédicas, Universidad de La Laguna, Tenerife, Spain.

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http://dx.doi.org/10.3233/JAD-2010-1242DOI Listing
April 2010

VDAC and ERalpha interaction in caveolae from human cortex is altered in Alzheimer's disease.

Mol Cell Neurosci 2009 Nov 10;42(3):172-83. Epub 2009 Jul 10.

Laboratory of Cellular Neurobiology, Department of Physiology, Faculty of Medicine and Institute of Biomedical Technologies, University of La Laguna, 38071 Sta. Cruz de Tenerife, Spain.

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http://dx.doi.org/10.1016/j.mcn.2009.07.001DOI Listing
November 2009

LRRK2 and neurodegeneration.

Acta Neuropathol 2009 Mar 14;117(3):227-46. Epub 2009 Jan 14.

Institut de Neuropatologia, IDIBELL-Hospital Universitari de Bellvitge, Universitat de Barcelona, Hospitalet de LLobregat, CIBERNED, Barcelona, Spain.

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http://link.springer.com/10.1007/s00401-008-0478-8
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http://dx.doi.org/10.1007/s00401-008-0478-8DOI Listing
March 2009

Delineation of early changes in cases with progressive supranuclear palsy-like pathology. Astrocytes in striatum are primary targets of tau phosphorylation and GFAP oxidation.

Brain Pathol 2009 Apr 6;19(2):177-87. Epub 2008 May 6.

Institut de Neuropatologia, Servei Anatomia Patològica, IDIBELL-Hospital Universitari de Bellvitge, carrer Feixa Llarga s/n, Hospitalet de Llobregat, Spain.

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http://dx.doi.org/10.1111/j.1750-3639.2008.00173.xDOI Listing
April 2009

Coenzyme q induces tau aggregation, tau filaments, and Hirano bodies.

J Neuropathol Exp Neurol 2008 May;67(5):428-34

Centro de Biología Molecular "Severo Ochoa" (CSIC-UAM), Universidad Autónoma de Madrid, Madrid, Spain.

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http://dx.doi.org/10.1097/NEN.0b013e31816fc9b6DOI Listing
May 2008

Argyrophilic grain disease.

Brain 2008 Jun 29;131(Pt 6):1416-32. Epub 2008 Jan 29.

Institut Neuropatologia, Servei Anatomia Patològica, IDIBELL-Hospital Universitari de Bellvitge, carrer Feixa LLarga sn, 08907 Hospitalet de Llobregat, Spain.

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http://dx.doi.org/10.1093/brain/awm305DOI Listing
June 2008

C-terminal end and aminoacid Lys48 in HMG-CoA lyase are involved in substrate binding and enzyme activity.

Mol Genet Metab 2007 Jun 24;91(2):120-7. Epub 2007 Apr 24.

Department of Biochemistry and Molecular Biology, School of Health Sciences, Universitat Internacional de Catalunya, E-08195 Sant Cugat, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.ymgme.2007.03.007DOI Listing
June 2007

Expression of transcription factors c-Fos, c-Jun, CREB-1 and ATF-2, and caspase-3 in relation with abnormal tau deposits in Pick's disease.

Acta Neuropathol 2006 Apr 23;111(4):341-50. Epub 2006 Feb 23.

Unitat de Neuropatologia Experimental, Universitat de Barcelona, Hospitalet de Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.1007/s00401-005-0013-0DOI Listing
April 2006

Low molecular weight species of tau in Alzheimer's disease are dependent on tau phosphorylation sites but not on delayed post-mortem delay in tissue processing.

Neurosci Lett 2006 May 20;399(1-2):106-10. Epub 2006 Feb 20.

Institut Neuropatologia, Servei Anatomia Patològica, IDIBELL-Hospital Universitari de Bellvitge, Universitat de Barcelona, 08907 Hospitalet de Llobregat, Spain.

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http://dx.doi.org/10.1016/j.neulet.2006.01.036DOI Listing
May 2006