Gabriel R Fries

Gabriel R Fries

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Gabriel R Fries

Publications by authors named "Gabriel R Fries"

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MicroRNA dysregulation in manic and euthymic patients with bipolar disorder.

J Affect Disord 2019 Sep 12;261:84-90. Epub 2019 Sep 12.

Department of Psychiatry, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.

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http://dx.doi.org/10.1016/j.jad.2019.09.060DOI Listing
September 2019

MicroRNAs in Major Depressive Disorder.

Adv Exp Med Biol 2019;1118:175-190

Translational Psychiatry Program, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA.

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http://dx.doi.org/10.1007/978-3-030-05542-4_9DOI Listing
August 2019

Preliminary investigation of peripheral extracellular vesicles' microRNAs in bipolar disorder.

J Affect Disord 2019 Aug 14;255:10-14. Epub 2019 May 14.

Translational Psychiatry Program, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth), 1941 East Rd, Houston, TX, United States; Translational Psychiatry Laboratory, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, SC, Brazil; Center of Excellence in Mood Disorders, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, United States; Neuroscience Graduate Program, The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, United States.

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http://dx.doi.org/10.1016/j.jad.2019.05.020DOI Listing
August 2019

Preliminary examination of the orexin system on relapse-related factors in cocaine use disorder.

Brain Res 2019 Jul 30:146359. Epub 2019 Jul 30.

Department of Psychiatry and Behavioral Sciences, UTHealth McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA; MD Anderson - UTHealth Graduate School of Biomedical Sciences, Program in Neuroscience, University of Texas Health Science Center at Houston, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.brainres.2019.146359DOI Listing
July 2019

TSPO upregulation in bipolar disorder and concomitant downregulation of mitophagic proteins and NLRP3 inflammasome activation.

Neuropsychopharmacology 2019 06 11;44(7):1291-1299. Epub 2018 Dec 11.

Translational Psychiatry Program, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA.

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http://dx.doi.org/10.1038/s41386-018-0293-4DOI Listing
June 2019

Moving pharmacoepigenetics tools for depression toward clinical use.

J Affect Disord 2019 Apr 6;249:336-346. Epub 2019 Feb 6.

Department of Psychiatry and Behavioral Sciences, School of Medicine, Emory University, Atlanta, GA, USA.

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http://dx.doi.org/10.1016/j.jad.2019.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763314PMC
April 2019

Analyzing leukocyte telomere length in bipolar disorder: Authors' reply.

Braz J Psychiatry 2017 Jul-Sep;39(3):275-276

Laborató rio de Psiquiatria Molecular, Hospital de Clínicas de Porto Alegre, UFRGS, Porto Alegre, RS, Brazil.

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http://dx.doi.org/10.1590/1516-4446-2017-2350DOI Listing
March 2019

Revisiting inflammation in bipolar disorder.

Pharmacol Biochem Behav 2019 Feb 24;177:12-19. Epub 2018 Dec 24.

Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, 77054 East Rd., Houston, TX, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.pbb.2018.12.006DOI Listing
February 2019

Are lithium effects dependent on genetic/epigenetic architecture?

Neuropsychopharmacology 2019 01;44(1):228

Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.

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http://dx.doi.org/10.1038/s41386-018-0194-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235883PMC
January 2019

Biomarkers for bipolar disorder: current status and challenges ahead.

Expert Rev Neurother 2019 Jan 28;19(1):67-81. Epub 2018 Nov 28.

a Department of Psychiatry & Behavioral Sciences , McGovern Medical School, UT Health , Houston , TX , USA.

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http://dx.doi.org/10.1080/14737175.2019.1550361DOI Listing
January 2019

Exosomal MicroRNAs as Potential Biomarkers in Neuropsychiatric Disorders.

Methods Mol Biol 2018 ;1733:79-85

Translational Psychiatry Program, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA.

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http://dx.doi.org/10.1007/978-1-4939-7601-0_6DOI Listing
December 2018

Expression of dopamine signaling genes in the post-mortem brain of individuals with mental illnesses is moderated by body mass index and mediated by insulin signaling genes.

J Psychiatr Res 2018 12 27;107:128-135. Epub 2018 Oct 27.

Mood Disorders Psychopharmacology Unit (MDPU), University Health Network, University of Toronto, Toronto, Canada; University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.jpsychires.2018.10.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278951PMC
December 2018

The impact of body mass index in gene expression of reelin pathway mediators in individuals with schizophrenia and mood disorders: A post-mortem study.

J Psychiatr Res 2018 07 13;102:186-191. Epub 2018 Apr 13.

Mood Disorders Psychopharmacology Unit (MDPU), University Health Network, Toronto, Canada; University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2018.04.012DOI Listing
July 2018

The miRNome of bipolar disorder.

J Affect Disord 2018 06 23;233:110-116. Epub 2017 Sep 23.

Translational Psychiatry Program, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, USA; Center of Excellence on Mood Disorders, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA; Neuroscience Graduate Program, The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA; Laboratory of Neurosciences, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina (UNESC), Criciúma, SC, Brazil.

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http://dx.doi.org/10.1016/j.jad.2017.09.025DOI Listing
June 2018

Elevated Plasma S100B, Psychotic Symptoms, and Cognition in Schizophrenia.

Psychiatr Q 2018 03;89(1):53-60

Harris County Psychiatric Center, University of Texas Health Science Center at Houston, 2800 South MacGregor Way, Houston, TX, 77021, USA.

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http://dx.doi.org/10.1007/s11126-017-9514-yDOI Listing
March 2018

Genome-wide expression in veterans with schizophrenia further validates the immune hypothesis for schizophrenia.

Schizophr Res 2018 02 20;192:255-261. Epub 2017 Jun 20.

Translational Psychiatry Program, Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, 1941 East Rd, 77054 Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2017.06.016DOI Listing
February 2018

The FKBP51 Glucocorticoid Receptor Co-Chaperone: Regulation, Function, and Implications in Health and Disease.

Int J Mol Sci 2017 Dec 5;18(12). Epub 2017 Dec 5.

Department of Translational Science in Psychiatry, Max Planck Institute of Psychiatry, 80804 Munich, Germany.

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http://dx.doi.org/10.3390/ijms18122614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751217PMC
December 2017

Accelerated epigenetic aging and mitochondrial DNA copy number in bipolar disorder.

Transl Psychiatry 2017 12 11;7(12):1283. Epub 2017 Dec 11.

Translational Psychiatry Program, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston (UTHealth), 1941 East Rd, 77054, Houston, TX, USA.

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http://dx.doi.org/10.1038/s41398-017-0048-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802567PMC
December 2017

Biomarkers in first-degree relatives of patients with bipolar disorder: what can they tell us?

Braz J Psychiatry 2017 Jul-Sep;39(3):277-278

Translational Psychiatry Program, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA.

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http://dx.doi.org/10.1590/1516-4446-2017-2302DOI Listing
November 2017

Distinct lithium-induced gene expression effects in lymphoblastoid cell lines from patients with bipolar disorder.

Eur Neuropsychopharmacol 2017 11 20;27(11):1110-1119. Epub 2017 Sep 20.

Translational Psychiatry Program, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, United States. Electronic address:

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http://dx.doi.org/10.1016/j.euroneuro.2017.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685885PMC
November 2017

Shortened telomere length in bipolar disorder: a comparison of the early and late stages of disease.

Braz J Psychiatry 2016 Oct-Dec;38(4):281-286. Epub 2016 Oct 17.

Laboratório de Psiquiatria Molecular, Hospital de Clínicas de Porto Alegre, UFRGS, Porto Alegre, RS, Brazil.

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http://dx.doi.org/10.1590/1516-4446-2016-1910DOI Listing
May 2017

Cognition and functioning in bipolar depression.

Braz J Psychiatry 2016 Jul-Sep;38(3):201-6. Epub 2016 May 2.

Laboratório de Psiquiatria Molecular, Instituto Nacional de Ciência e Tecnologia - Medicina Translacional (INCT-TM), Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.

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http://dx.doi.org/10.1590/1516-4446-2014-1558DOI Listing
April 2017

The FKBP51-Glucocorticoid Receptor Balance in Stress-Related Mental Disorders.

Curr Mol Pharmacol 2015 ;9(2):126-40

Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany.

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October 2016

The role of DNA methylation in the pathophysiology and treatment of bipolar disorder.

Neurosci Biobehav Rev 2016 Sep 18;68:474-488. Epub 2016 Jun 18.

Translational Psychiatry Program, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston (UTHealth), 1941 East Rd, 77054, Houston, TX, USA; Center of Excellence on Mood Disorders, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth), Houston, TX, USA; Neuroscience Graduate Program, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX, USA; Laboratory of Neurosciences, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina (UNESC), Criciúma, SC, Brazil.

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http://dx.doi.org/10.1016/j.neubiorev.2016.06.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003658PMC
September 2016

Modeling mania in preclinical settings: A comprehensive review.

Prog Neuropsychopharmacol Biol Psychiatry 2016 Apr 4;66:22-34. Epub 2015 Nov 4.

Center for Translational Psychiatry, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, Houston, TX 77054, USA; Center of Excellence on Mood Disorders, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, Houston, TX 77054, USA; Laboratory of Neurosciences, Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, SC, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2015.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728043PMC
April 2016

Memory and brain-derived neurotrophic factor after subchronic or chronic amphetamine treatment in an animal model of mania.

J Psychiatr Res 2015 Sep 15;68:329-36. Epub 2015 May 15.

Laboratory of Genetic Identification and Medical Genetic Service, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350, 90035-903, Rio Grande do Sul, Brazil; Department of Biochemistry, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos, 2600, 90035-903, Rio Grande do Sul, Brazil. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00223956150014
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http://dx.doi.org/10.1016/j.jpsychires.2015.05.006DOI Listing
September 2015

Neurotrophins, inflammation and oxidative stress as illness activity biomarkers in bipolar disorder.

Expert Rev Neurother 2013 Jul;13(7):827-42

Laboratório de Psiquiatria Molecular, Instituto Nacional de Ciência e Tecnologia - Translacional em Medicina, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

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http://dx.doi.org/10.1586/14737175.2013.811981DOI Listing
July 2013

Peripheral toxicity in crack cocaine use disorders.

Neurosci Lett 2013 Jun 15;544:80-4. Epub 2013 Apr 15.

Bipolar Disorders Program & INCT Translational Medicine, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.

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http://dx.doi.org/10.1016/j.neulet.2013.03.045DOI Listing
June 2013

Effects of experimental cerebral malaria in memory, brain-derived neurotrophic factor and acetylcholinesterase activity [correction for acitivity] in the hippocampus of survivor mice.

Neurosci Lett 2012 Aug 27;523(2):104-7. Epub 2012 Jun 27.

Laboratory of Neurosciences and National Institute for Translational Medicine (INCT-TM), Postgraduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, 88806-000 Criciúma, SC, Brazil.

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http://dx.doi.org/10.1016/j.neulet.2012.06.051DOI Listing
August 2012

Memantine treatment reverses anhedonia, normalizes corticosterone levels and increases BDNF levels in the prefrontal cortex induced by chronic mild stress in rats.

Metab Brain Dis 2012 Jun 11;27(2):175-82. Epub 2012 Feb 11.

Laboratório de Neurociências and Instituto Nacional de Ciência e Tecnologia, Translacional em Medicina, Programa de Pós-Graduação em Ciências da Saúde, Unidade Acadêmica de Ciências da Saúde, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.

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http://dx.doi.org/10.1007/s11011-012-9281-2DOI Listing
June 2012

Administration of cannabidiol and imipramine induces antidepressant-like effects in the forced swimming test and increases brain-derived neurotrophic factor levels in the rat amygdala.

Acta Neuropsychiatr 2011 Oct;23(5):241-8

Laboratório de Neurociências and Instituto Nacional de Ciência e Tecnologia Translacional em Medicina (INCT-TM), Programa de Pós-Graduação em Ciências da Saúde, Unidade Acadêmica de Ciências da Saúde, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.

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http://dx.doi.org/10.1111/j.1601-5215.2011.00579.xDOI Listing
October 2011

Therapeutic use of omega-3 fatty acids in bipolar disorder.

Expert Rev Neurother 2011 Jul;11(7):1029-47

Section of Psychiatry, Department of Medicine, CIBERSAM University of Valencia Medical School, Valencia, Spain.

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http://dx.doi.org/10.1586/ern.11.42DOI Listing
July 2011

Neuroanatomical profile of antimaniac effects of histone deacetylases inhibitors.

Mol Neurobiol 2011 Jun 22;43(3):207-14. Epub 2011 Mar 22.

Laboratory of Neurosciences and National Institute for Translational Medicine (INCT-TM), Postgraduate Program in Health Sciences, University of Southern Santa Catarina, Criciúma, SC, Brazil.

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http://dx.doi.org/10.1007/s12035-011-8178-0DOI Listing
June 2011

Chronic administration of harmine elicits antidepressant-like effects and increases BDNF levels in rat hippocampus.

J Neural Transm (Vienna) 2010 Oct 5;117(10):1131-7. Epub 2010 Aug 5.

Laboratório de Neurociências and Instituto Nacional de Ciência e Tecnologia Translacional em Medicina (INCT-TM), Programa de Pós-Graduação em Ciências da Saúde, Unidade Acadêmica de Ciências da Saúde, Universidade do Extremo Sul Catarinense, Criciúma, SC 88806-000, Brazil.

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http://dx.doi.org/10.1007/s00702-010-0451-2DOI Listing
October 2010

Effects of mood stabilizers on hippocampus and amygdala BDNF levels in an animal model of mania induced by ouabain.

J Psychiatr Res 2010 Jun 1;44(8):506-10. Epub 2009 Dec 1.

Laboratory of Neurosciences and National Science and Technology Institute for Translational Medicine, Postgraduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, 88808-000 Criciúma, SC, Brazil.

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http://dx.doi.org/10.1016/j.jpsychires.2009.11.002DOI Listing
June 2010

Effects of moderate exercise on cigarette smoke exposure-induced hippocampal oxidative stress values and neurological behaviors in mice.

Neurosci Lett 2010 May 18;475(1):16-9. Epub 2010 Mar 18.

Exercise Biochemistry and Physiology Laboratory, Postgraduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, Criciúma, SC, Brazil.

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http://dx.doi.org/10.1016/j.neulet.2010.03.030DOI Listing
May 2010

Neurochemical and behavioural effects of acute and chronic memantine administration in rats: Further support for NMDA as a new pharmacological target for the treatment of depression?

Brain Res Bull 2010 Apr 30;81(6):585-9. Epub 2009 Nov 30.

Laboratório de Neurociências and Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Programa de Pós-Graduação em Ciências da Saúde, Unidade Acadêmica de Ciências da Saúde, Universidade do Extremo Sul Catarinense, 88806-000 Criciúma, SC, Brazil.

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http://dx.doi.org/10.1016/j.brainresbull.2009.11.013DOI Listing
April 2010

Effects of beta-carboline harmine on behavioral and physiological parameters observed in the chronic mild stress model: further evidence of antidepressant properties.

Brain Res Bull 2010 Mar 20;81(4-5):491-6. Epub 2009 Sep 20.

Laboratório de Neurociências and Instituto Nacional de Ciência e Tecnologia Translacional em Medicina, Programa de Pós-Graduação em Ciências da Saúde, Unidade Acadêmica de Ciências da Saúde, Universidade do Extremo Sul Catarinense, 88806-000 Criciúma, SC, Brazil.

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http://dx.doi.org/10.1016/j.brainresbull.2009.09.008DOI Listing
March 2010

Increased serum neurotrophin-4/5 levels in bipolar disorder.

J Psychiatr Res 2009 Apr 10;43(7):721-3. Epub 2008 Dec 10.

Bipolar Disorders Program and Molecular Psychiatry Laboratory, Hospital de Clínicas de Porto Alegre (HCPA), Universidade Federal do Rio Grande do Sul, Ramiro Barcelos, 2350, CEP 90035-003, Porto Alegre, RS, Brazil.

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http://dx.doi.org/10.1016/j.jpsychires.2008.10.005DOI Listing
April 2009

Chronic administration of ketamine elicits antidepressant-like effects in rats without affecting hippocampal brain-derived neurotrophic factor protein levels.

Basic Clin Pharmacol Toxicol 2008 Dec;103(6):502-6

Laboratory of Neurosciences, Postgraduate Program in Health Sciences, University of the Far South Catarinense, Criciuma, SC, Brazil.

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http://dx.doi.org/10.1111/j.1742-7843.2008.00210.xDOI Listing
December 2008

Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus.

Prog Neuropsychopharmacol Biol Psychiatry 2008 Jan 8;32(1):140-4. Epub 2007 Aug 8.

Laboratório de Neurociências, Programa de Pós-Graduação em Ciências da Saúde, Unidade Acadêmica de Ciências da Saúde, Universidade do Extremo Sul Catarinense, 88806-000 Criciúma, SC, Brazil.

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http://linkinghub.elsevier.com/retrieve/pii/S027858460700269
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http://dx.doi.org/10.1016/j.pnpbp.2007.07.027DOI Listing
January 2008