Gabriel Lopez-Berestein

Gabriel Lopez-Berestein

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Gabriel Lopez-Berestein

Publications by authors named "Gabriel Lopez-Berestein"

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100Publications

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Telomere Dysfunction Induces Sirtuin Repression that Drives Telomere-Dependent Disease.

Cell Metab 2019 Jun 28;29(6):1274-1290.e9. Epub 2019 Mar 28.

Department of Physiology and Biophysics, Baylor College of Medicine, Houston, TX 77030, USA; Huffington Center on Aging, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.03.001DOI Listing
June 2019

Pan-cancer genomic analysis links 3'UTR DNA methylation with increased gene expression in T cells.

EBioMedicine 2019 May 2;43:127-137. Epub 2019 May 2.

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.04.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558231PMC
May 2019

The Modulatory Role of MicroRNA-873 in the Progression of KRAS-Driven Cancers.

Mol Ther Nucleic Acids 2019 Mar 13;14:301-317. Epub 2018 Dec 13.

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Center for RNA Interference and Non-Coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.omtn.2018.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348737PMC
March 2019

Autophagy is Required to Regulate Mitochondria Renewal, Cell Attachment, and All-trans-Retinoic Acid-Induced Differentiation in NB4 Acute Promyelocytic Leukemia Cells.

J Environ Pathol Toxicol Oncol 2019 ;38(1):13-20

Department of Experimental Therapeutics, The University of Texas M.D. Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1615/JEnvironPatholToxicolOncol.2018027885DOI Listing
March 2019

PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis.

EBioMedicine 2019 Feb 14;40:290-304. Epub 2019 Jan 14.

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.11.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411965PMC
February 2019

Presence of Circulating miR-145, miR-155, and miR-382 in Exosomes Isolated from Serum of Breast Cancer Patients and Healthy Donors.

Dis Markers 2019 12;2019:6852917. Epub 2019 Feb 12.

Universidad Autónoma de Nuevo León, College of Biological Sciences, Department of Cellular Biology and Genetics, San Nicolás de los Garza, Nuevo León, Mexico.

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http://dx.doi.org/10.1155/2019/6852917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390256PMC
February 2019

Exosomal miRNA confers chemo resistance via targeting Cav1/p-gp/M2-type macrophage axis in ovarian cancer.

EBioMedicine 2018 Dec 25;38:100-112. Epub 2018 Nov 25.

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S23523964183049
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http://dx.doi.org/10.1016/j.ebiom.2018.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306310PMC
December 2018

Thymoquinone inhibits cell proliferation, migration, and invasion by regulating the elongation factor 2 kinase (eEF-2K) signaling axis in triple-negative breast cancer.

Breast Cancer Res Treat 2018 Oct 3;171(3):593-605. Epub 2018 Jul 3.

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 422, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1007/s10549-018-4847-2DOI Listing
October 2018

Bone protection by inhibition of microRNA-182.

Nat Commun 2018 10 5;9(1):4108. Epub 2018 Oct 5.

Arthritis and Tissue Degeneration Program, The David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, 10021, NY, USA.

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http://dx.doi.org/10.1038/s41467-018-06446-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173760PMC
October 2018

Chitosan Nanoparticles for miRNA Delivery.

Methods Mol Biol 2017 ;1632:219-230

Center for RNA Interference and Non-coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1007/978-1-4939-7138-1_14DOI Listing
April 2018

RNA interference-based therapy and its delivery systems.

Cancer Metastasis Rev 2018 03;37(1):107-124

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1007/s10555-017-9717-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898634PMC
March 2018

Cancer-associated fibroblasts regulate endothelial adhesion protein LPP to promote ovarian cancer chemoresistance.

J Clin Invest 2018 02 18;128(2):589-606. Epub 2017 Dec 18.

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1172/JCI95200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785271PMC
February 2018

MYC Targeted Long Noncoding RNA DANCR Promotes Cancer in Part by Reducing p21 Levels.

Cancer Res 2018 01 27;78(1):64-74. Epub 2017 Nov 27.

Abramson Family Cancer Research Institute, Abramson Cancer Center and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-0815DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993051PMC
January 2018

Differential Effects of EGFL6 on Tumor versus Wound Angiogenesis.

Cell Rep 2017 Dec;21(10):2785-2795

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.11.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749980PMC
December 2017

Therapeutic Targeting of AXL Receptor Tyrosine Kinase Inhibits Tumor Growth and Intraperitoneal Metastasis in Ovarian Cancer Models.

Mol Ther Nucleic Acids 2017 Dec 5;9:251-262. Epub 2017 Jul 5.

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.omtn.2017.06.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675720PMC
December 2017

Role of Platelet-Derived Tgfβ1 in the Progression of Ovarian Cancer.

Clin Cancer Res 2017 Sep 13;23(18):5611-5621. Epub 2017 Jun 13.

Department of Benign Hematology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-3272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600833PMC
September 2017

miR-200c-driven Mesenchymal-To-Epithelial Transition is a Therapeutic Target in Uterine Carcinosarcomas.

Sci Rep 2017 06 15;7(1):3614. Epub 2017 Jun 15.

Gynecologic Oncology, Laura and Isaac Perlmutter Cancer Center, NYU Langone Medical Center, New York, NY, 10016, USA.

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http://dx.doi.org/10.1038/s41598-017-03972-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472620PMC
June 2017

Inhibition Synergistically Enhances the Effects of Magnetic Fluid Hyperthermia in Ovarian Cancer.

Mol Cancer Ther 2017 05 21;16(5):966-976. Epub 2017 Feb 21.

Department of Chemical Engineering, University of Puerto Rico-Mayagüez, Mayagüez, Puerto Rico.

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http://dx.doi.org/10.1158/1535-7163.MCT-16-0519DOI Listing
May 2017

Role of CTGF in Sensitivity to Hyperthermia in Ovarian and Uterine Cancers.

Cell Rep 2016 11;17(6):1621-1631

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center (MDACC), Houston, TX 77030, USA; Center for RNA Interference and Non-Coding RNAs, MDACC, Houston, TX 77030, USA; Department of Cancer Biology, MDACC, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.10.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123842PMC
November 2016

Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth.

Cell Metab 2016 11;24(5):685-700

Laboratory for Systems Biology of Human Diseases, Rice University, Houston, TX 77005, USA; Department of Chemical and Biomolecular Engineering, Rice University, Houston, TX 77005, USA; Department of Bioengineering, Rice University, Houston, TX 77005, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.10.011DOI Listing
November 2016

Profiling Long Noncoding RNA Expression Using Custom-Designed Microarray.

Methods Mol Biol 2016 ;1402:33-41

Center for RNA Interference and Non-Coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1007/978-1-4939-3378-5_5DOI Listing
October 2016

Assessment of In Vivo siRNA Delivery in Cancer Mouse Models.

Methods Mol Biol 2016 ;1402:189-197

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center (MDACC), Houston, TX, 77054, USA.

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http://dx.doi.org/10.1007/978-1-4939-3378-5_15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142631PMC
October 2016

microRNA Therapeutics in Cancer - An Emerging Concept.

EBioMedicine 2016 Oct 20;12:34-42. Epub 2016 Sep 20.

Departments of Experimental Therapeutics and Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA and Center for RNA Interference and Non-Coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2016.09.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078622PMC
October 2016

ΔNp63/DGCR8-Dependent MicroRNAs Mediate Therapeutic Efficacy of HDAC Inhibitors in Cancer.

Cancer Cell 2016 06;29(6):874-888

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA; Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.04.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908836PMC
June 2016

Adrenergic Stimulation of DUSP1 Impairs Chemotherapy Response in Ovarian Cancer.

Clin Cancer Res 2016 Apr 18;22(7):1713-24. Epub 2015 Nov 18.

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas. Center for RNAi and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, Texas. Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-1275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818718PMC
April 2016

Linalool-Incorporated Nanoparticles as a Novel Anticancer Agent for Epithelial Ovarian Carcinoma.

Mol Cancer Ther 2016 04 9;15(4):618-27. Epub 2016 Feb 9.

Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea. Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, South Korea.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0733-TDOI Listing
April 2016

Differentiation therapy for hepatocellular carcinoma: Multifaceted effects of miR-148a on tumor growth and phenotype and liver fibrosis.

Hepatology 2016 Mar 14;63(3):864-79. Epub 2016 Jan 14.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1002/hep.28367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764447PMC
March 2016

miRNA Deregulation in Cancer Cells and the Tumor Microenvironment.

Cancer Discov 2016 Mar 10;6(3):235-46. Epub 2016 Feb 10.

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas. Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/2159-8290.CD-15-0893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783232PMC
March 2016

Role of Increased n-acetylaspartate Levels in Cancer.

J Natl Cancer Inst 2016 Jan 26;108(6):djv426. Epub 2016 Jan 26.

Departments of Gynecologic Oncology and Reproductive Medicine (BZ, RAP, RR, TM, ASN, HJD, WH, CI, SYW, KMG, SP, LSM, AMN, GAP, AKS), Cancer Systems Imaging (NMZ, CRM, PKB), Biostatistics (MG), Cancer Medicine (CVP), Center for RNA Interference and Non-Coding RNA (CI, LSM, CRA, GLB, AKS), Cancer Biology (YS, MBE, GLB, AKS), Experimental Therapeutics (CRA, GLB), Bioinformatics and Computational Biology (YW, KAB), Melanoma Medical Oncology (MAD), and Pathology (JL), University of Texas M. D. Anderson Cancer Center, Houston, TX; Department of Nanomedicine and Bioengineering, UT Health, Houston, TX (GLB, AKS); Departments of Psychology, Urology, and Obstetrics and Gynecology, the University of Iowa, Iowa City, IA (SKL); Laboratory for Systems Biology of Human Diseases (LY, JB, AA, DN), Department of Chemical and Biomolecular Engineering (LY, JB, AA, DN), and Department of Bioengineering (DN), Rice University, Houston, TX.

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http://dx.doi.org/10.1093/jnci/djv426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849357PMC
January 2016

Long Noncoding RNA Ceruloplasmin Promotes Cancer Growth by Altering Glycolysis.

Cell Rep 2015 Dec 10;13(11):2395-2402. Epub 2015 Dec 10.

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for RNA Interference and Non-Coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.11.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691557PMC
December 2015

Augmentation of response to chemotherapy by microRNA-506 through regulation of RAD51 in serous ovarian cancers.

J Natl Cancer Inst 2015 Jul 20;107(7). Epub 2015 May 20.

: Departments of Pathology (GL, DY, YS, XL, PJ, DC, LH, WZ), Experimental Therapeutics (CRA, GLB), and Gynecologic Oncology and Reproductive Medicine (RR, LSM, AKS), Division of Cancer Medicine (CVP), Center for RNAi and Non-Coding RNA (RR, CVP, LSM, CRA, GLB, AKS, WZ), the University of Texas MD Anderson Cancer Center, Houston, TX; Department of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, China (GL, YW, FX); Department of Pathology (YS) and Epidemiology (KC), Tianjin Medical University Cancer Institute and Hospital, Tianjin, China; Department of Biochemistry and Molecular Biology, State Key Laboratory of Cancer Biology, the Fourth Military Medical University, Xi'an, China (XL); Institute for Systems Biology, Seattle, WA (IS); Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy (LDC, DM).

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http://academic.oup.com/jnci/article/doi/10.1093/jnci/djv108
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http://dx.doi.org/10.1093/jnci/djv108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554255PMC
July 2015

Nanotechnology: Future of Oncotherapy.

Clin Cancer Res 2015 Jul;21(14):3121-30

Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Center for RNA Interference and Non-Coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505622PMC
July 2015

Preclinical and clinical development of siRNA-based therapeutics.

Adv Drug Deliv Rev 2015 Jun 7;87:108-19. Epub 2015 Feb 7.

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2015.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504743PMC
June 2015

Exosomal Non-Coding RNAs: Diagnostic, Prognostic and Therapeutic Applications in Cancer.

Noncoding RNA 2015 Jun 3;1(1):53-68. Epub 2015 Jun 3.

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Centre, Houston, TX, 77054, USA.

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http://dx.doi.org/10.3390/ncrna1010053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932539PMC
June 2015

Rac1/Pak1/p38/MMP-2 Axis Regulates Angiogenesis in Ovarian Cancer.

Clin Cancer Res 2015 May 16;21(9):2127-37. Epub 2015 Jan 16.

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Center for RNAi and Non-coding RNA, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://clincancerres.aacrjournals.org/content/early/2015/01/
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http://clincancerres.aacrjournals.org/content/early/2015/03/
Web Search
http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-14-2279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417466PMC
May 2015

TP53 loss creates therapeutic vulnerability in colorectal cancer.

Nature 2015 Apr 22;520(7549):697-701. Epub 2015 Apr 22.

1] Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA [2] Center for RNA Interference and Non-coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/nature14418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417759PMC
April 2015

MiR-506 inhibits multiple targets in the epithelial-to-mesenchymal transition network and is associated with good prognosis in epithelial ovarian cancer.

J Pathol 2015 Jan 6;235(1):25-36. Epub 2014 Nov 6.

Department of Pathology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, 300060, China; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1002/path.4443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268369PMC
January 2015

Therapeutic silencing of KRAS using systemically delivered siRNAs.

Mol Cancer Ther 2014 Dec 3;13(12):2876-85. Epub 2014 Oct 3.

Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1535-7163.MCT-14-0074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416486PMC
December 2014

miR-205 acts as a tumour radiosensitizer by targeting ZEB1 and Ubc13.

Nat Commun 2014 Dec 5;5:5671. Epub 2014 Dec 5.

1] Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA [2] Cancer Biology and Genes &Development Programs, Graduate School of Biomedical Sciences, The University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/ncomms6671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377070PMC
December 2014

Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential.

Nat Commun 2014 Oct 3;5:5092. Epub 2014 Oct 3.

1] Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA [2] The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/ncomms6092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185407PMC
October 2014

Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression.

Nat Commun 2014 Oct 29;5:5202. Epub 2014 Oct 29.

1] Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA [2] Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA [3] Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/ncomms6202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215647PMC
October 2014

Clodronate inhibits tumor angiogenesis in mouse models of ovarian cancer.

Cancer Biol Ther 2014 Aug 19;15(8):1061-7. Epub 2014 May 19.

Department of Gynecologic Oncology and Reproductive Medicine; The University of Texas MD Anderson Cancer Center; Houston, TX USA; Department of Cancer Biology; The University of Texas MD Anderson Cancer Center; Houston, TX USA; Center for RNA Interference and Non-Coding RNA; The University of Texas MD Anderson Cancer Center; Houston, TX USA.

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http://dx.doi.org/10.4161/cbt.29184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119073PMC
August 2014

miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2.

Nature 2014 Aug 25;512(7515):431-5. Epub 2014 Jun 25.

1] Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA [2] Simmons Cancer Center, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1038/nature13375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149606PMC
August 2014

Focal adhesion kinase: an alternative focus for anti-angiogenesis therapy in ovarian cancer.

Cancer Biol Ther 2014 Jul 23;15(7):919-29. Epub 2014 Apr 23.

Department of Gynecologic Oncology; The University of Texas M.D. Anderson Cancer Center; Houston, TX USA; Department of Cancer Biology; The University of Texas M.D. Anderson Cancer Center; Houston, TX USA.

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http://dx.doi.org/10.4161/cbt.28882DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100993PMC
July 2014

Hematogenous metastasis of ovarian cancer: rethinking mode of spread.

Cancer Cell 2014 Jul;26(1):77-91

Department of Gynecologic Oncology and Reproductive Medicine, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA; Department of Cancer Biology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA; Center for RNA Interference and Non-coding RNA, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100212PMC
July 2014

Molecular biomarkers of residual disease after surgical debulking of high-grade serous ovarian cancer.

Clin Cancer Res 2014 Jun 22;20(12):3280-8. Epub 2014 Apr 22.

Authors' Affiliations: Departments of Bioinformatics and Computational Biology, Gynecologic Oncology and Reproductive Medicine, Experimental Therapeutics, Cancer Biology, and Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, Texas; and Fred Hutchinson Cancer Research Center, Seattle, WashingtonAuthors' Affiliations: Departments of Bioinformatics and Computational Biology, Gynecologic Oncology and Reproductive Medicine, Experimental Therapeutics, Cancer Biology, and Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, Texas; and Fred Hutchinson Cancer Research Center, Seattle, WashingtonAuthors' Affiliations: Departments of Bioinformatics and Computational Biology, Gynecologic Oncology and Reproductive Medicine, Experimental Therapeutics, Cancer Biology, and Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, Texas; and Fred Hutchinson Cancer Research Center, Seattle, Washington

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-14-0445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062703PMC
June 2014

RNAi therapies: drugging the undruggable.

Sci Transl Med 2014 Jun;6(240):240ps7

Departments of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230, USA. Center for RNA Interference and Non-Coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, TX 77230, USA. Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230, USA.

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http://stm.sciencemag.org/cgi/doi/10.1126/scitranslmed.30083
Publisher Site
http://dx.doi.org/10.1126/scitranslmed.3008362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154139PMC
June 2014