Gabor K Toth

Gabor K Toth

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Gabor K Toth

Publications by authors named "Gabor K Toth"

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Corrigendum to "Age-dependent changes at the blood-brain barrier. A comparative structural and functional study in young adult and middle aged rats" [Brain Res. Bull. 139C (2018) 269-277].

Brain Res Bull 2020 Feb 24;155:211-212. Epub 2019 Nov 24.

Pázmány Péter Catholic University, Faculty of Information Technology and Bionics, Práter u. 50a, H-1083, Budapest, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.brainresbull.2019.11.003DOI Listing
February 2020

Immunomodulatory Effects of the Neuropeptide Pituitary Adenylate Cyclase-Activating Polypeptide in Acute .

Front Cell Infect Microbiol 2019 28;9:154. Epub 2019 May 28.

Medical Faculty, Institute of Inflammation and Neurodegeneration, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.

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http://dx.doi.org/10.3389/fcimb.2019.00154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546896PMC
January 2020

Enantioselective resolution of biologically active dipeptide analogs by high-performance liquid chromatography applying Cinchona alkaloid-based ion-exchanger chiral stationary phases.

J Chromatogr A 2020 Jan 27;1611:460574. Epub 2019 Sep 27.

Institute of Pharmaceutical Analysis, Interdisciplinary Excellence Centre, University of Szeged, H-6720 Szeged, Somogyi u. 4, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.chroma.2019.460574DOI Listing
January 2020

Compactness of Protein Folds Alters Disulfide-Bond Reducibility by Three Orders of Magnitude: A Comprehensive Kinetic Case Study on the Reduction of Differently Sized Tryptophan Cage Model Proteins.

Chembiochem 2019 Sep 2. Epub 2019 Sep 2.

Laboratory of Structural Chemistry and Biology and, MTA-ELTE Protein Modeling Research Group at the Institute of Chemistry, Eötvös Loránd University, 112, P. O. Box 32, 1518, Budapest, Hungary.

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http://dx.doi.org/10.1002/cbic.201900470DOI Listing
September 2019

Flow-chemistry enabled efficient synthesis of β-peptides: backbone topology vs. helix formation.

Chem Commun (Camb) 2019 Mar;55(21):3061-3064

Institute of Pharmaceutical Chemistry, University of Szeged, Eötvös u. 7., H-6720 Szeged, Hungary.

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http://dx.doi.org/10.1039/c8cc10147gDOI Listing
March 2019

Structure and Synthesis of Antifungal Disulfide β-Strand Proteins from Filamentous Fungi.

Microorganisms 2018 Dec 27;7(1). Epub 2018 Dec 27.

Department of Organic Chemistry, University of Debrecen, H-4032 Debrecen, Hungary.

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http://dx.doi.org/10.3390/microorganisms7010005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352176PMC
December 2018

Age-dependent changes at the blood-brain barrier. A Comparative structural and functional study in young adult and middle aged rats.

Brain Res Bull 2018 05 6;139:269-277. Epub 2018 Mar 6.

Pázmány Péter Catholic University, Faculty of Information Technology and Bionics, Práter u. 50a, H-1083 Budapest. Electronic address:

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http://dx.doi.org/10.1016/j.brainresbull.2018.03.001DOI Listing
May 2018

Synthesis of -peptide-6-amino-D-luciferin Conjugates.

Front Chem 2018 19;6:120. Epub 2018 Apr 19.

Department of Medical Chemistry, University of Szeged, Szeged, Hungary.

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http://dx.doi.org/10.3389/fchem.2018.00120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917020PMC
April 2018

Bacterial expression and/or solid phase peptide synthesis of 20-40 amino acid long polypeptides and miniproteins, the case study of Class B GPCR ligands.

Curr Protein Pept Sci 2016 ;17(2):147-55

Laboratory of Structural Chemistry and Biology, Institute of Chemistry, Eötvös Loránd University, Pázmány P. sétány 1/A, Budapest, H-1117 Hungary.

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http://dx.doi.org/10.2174/1389203716666151102105215DOI Listing
October 2016

Antiamnesic properties of analogs and mimetics of the tripeptide human urocortin 3.

Amino Acids 2016 09 4;48(9):2261-6. Epub 2016 Jun 4.

Department of Medical Chemistry, University of Szeged, Dóm tér 8, Szeged, 6720, Hungary.

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http://dx.doi.org/10.1007/s00726-016-2268-2DOI Listing
September 2016

Aromatic Cluster Sensor of Protein Folding: Near-UV Electronic Circular Dichroism Bands Assigned to Fold Compactness.

Chemistry 2016 Sep 9;22(39):13871-13883. Epub 2016 Aug 9.

MTA-ELTE Protein Modelling Research Group, Eötvös Loránd University, Pázmány P. sétány 1A, 1117, Budapest, Hungary.

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http://dx.doi.org/10.1002/chem.201602455DOI Listing
September 2016

Kinetic and Thermodynamic Evaluation of Kynurenic Acid Binding to GluR1270-300 Polypeptide by Surface Plasmon Resonance Experiments.

J Phys Chem B 2016 08 8;120(32):7844-50. Epub 2016 Aug 8.

MTA-SZTE Supramolecular and Nanostructured Materials Research Group and ‡Department of Medical Chemistry, Faculty of Medicine, University of Szeged , Dóm tér 8., Szeged H-6720, Hungary.

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http://dx.doi.org/10.1021/acs.jpcb.6b05682DOI Listing
August 2016

Probing pattern and dynamics of disulfide bridges using synthesis and NMR of an ion channel blocker peptide toxin with multiple diselenide bonds.

Chem Sci 2016 Apr 21;7(4):2666-2673. Epub 2015 Dec 21.

Department of Inorganic and Analytical Chemistry , University of Debrecen , Egyetem tér 1 , H-4032 , Debrecen , Hungary . Email:

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http://dx.doi.org/10.1039/c5sc03995aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477041PMC
April 2016

An engineered scorpion toxin analogue with improved Kv1.3 selectivity displays reduced conformational flexibility.

Sci Rep 2015 Dec 22;5:18397. Epub 2015 Dec 22.

MTA-DE-NAP B Ion Channel Structure-Function Research Group, RCMM, University of Debrecen, Debrecen, Egyetem tér 1, H-4032, Hungary.

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http://dx.doi.org/10.1038/srep18397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686915PMC
December 2015

Phosphorylation as conformational switch from the native to amyloid state: Trp-cage as a protein aggregation model.

J Phys Chem B 2015 Feb 6;119(7):2946-55. Epub 2015 Feb 6.

Department of Biochemistry, ‡MTA-ELTE NAP B Neuroimmunology Research Group, and §Department of Anatomy, Cell and Developmental Biology, Institute of Biology Eötvös Loránd University , Pázmány P. sétány 1/C, Budapest, H-1117 Hungary.

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http://dx.doi.org/10.1021/jp5124234DOI Listing
February 2015

Rational design of α-helix-stabilized exendin-4 analogues.

Biochemistry 2014 Jun 28;53(22):3540-52. Epub 2014 May 28.

Laboratory of Structural Chemistry and Biology, Institute of Chemistry, Eötvös Loránd University , Budapest, Hungary.

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http://pubs.acs.org/doi/10.1021/bi500033c
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http://dx.doi.org/10.1021/bi500033cDOI Listing
June 2014

Synthesis of novel pyrazole-based heterocycles via a copper(II)-catalysed domino annulation.

Org Biomol Chem 2013 Oct;11(37):6320-7

Avidin Ltd, Alsó Kikötő sor 11, Szeged, H-6726, Hungary.

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http://dx.doi.org/10.1039/c3ob41146jDOI Listing
October 2013

Synthesis and ABCG2 inhibitory activity of novel fumitremorgin C analogs--specificity and structure activity correlations.

Med Chem 2013 Jun;9(4):494-509

Department of Medical Chemistry, Faculty of General Medicine, University of Szeged, 6720 Szeged Dóm tér 8., Hungary.

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http://dx.doi.org/10.2174/1573406411309040003DOI Listing
June 2013

Synthesis and cytotoxic activity of 4-N-carboxybutyl-5-fluorocytosyl-Arg-Gln-Trp-Arg-Arg-Trp-Trp-Gln-Arg-NH₂.

Bioorg Med Chem Lett 2012 Jul 17;22(13):4233-7. Epub 2012 May 17.

Department of Medical Chemistry, Faculty of General Medicine, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.

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https://linkinghub.elsevier.com/retrieve/pii/S0960894X120064
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http://dx.doi.org/10.1016/j.bmcl.2012.05.045DOI Listing
July 2012

Copper(II)-binding ability of stereoisomeric cis- and trans-2-aminocyclohexanecarboxylic acid-L-phenylalanine dipeptides. A combined CW/pulsed EPR and DFT study.

Inorg Chem 2012 Feb 6;51(3):1386-99. Epub 2012 Jan 6.

Institute of Structural Chemistry, Chemical Research Center of the Hungarian Academy of Sciences, Pusztaszeri út 59-67, H-1025 Budapest, Hungary.

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http://dx.doi.org/10.1021/ic2016116DOI Listing
February 2012

Cooperativity network of Trp-cage miniproteins: probing salt-bridges.

J Pept Sci 2011 Sep 6;17(9):610-9. Epub 2011 Jun 6.

Laboratory of Structural Chemistry and Biology, Institute of Chemistry, Eötvös University, Budapest, Hungary.

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http://dx.doi.org/10.1002/psc.1377DOI Listing
September 2011

Synthesis of N-glycopeptides applying glycoamino Acid building blocks with a combined fmoc/boc strategy.

Protein Pept Lett 2011 Jul;18(7):679-83

Department of Medical Chemistry, Faculty of General Medicine, University of Szeged, 6720 Szeged Dóm tér 8., Hungary.

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http://dx.doi.org/10.2174/092986611795446003DOI Listing
July 2011

A simple chromatographic route for the isolation of meso diaminopimelic acid.

Chirality 2011 Feb 27;23(2):133-7. Epub 2010 Aug 27.

Department of Medical Chemistry, University of Szeged, Szeged, Hungary.

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http://dx.doi.org/10.1002/chir.20888DOI Listing
February 2011

Building β-peptide H10/12 foldamer helices with six-membered cyclic side-chains: fine-tuning of folding and self-assembly.

Org Lett 2010 Dec 4;12(23):5584-7. Epub 2010 Nov 4.

Institute of Pharmaceutical Chemistry, University of Szeged, H-6720 Szeged, Eötvös u. 6, Hungary.

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http://dx.doi.org/10.1021/ol102494mDOI Listing
December 2010

Stabilisation of Peptide foldamers in an aqueous medium by incorporation of azapeptide building blocks.

Chemistry 2009 Oct;15(41):10736-41

Institute of Pharmaceutical Chemistry, University of Szeged, 6720 Szeged, Eötvös u. 6, Hungary.

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http://dx.doi.org/10.1002/chem.200900724DOI Listing
October 2009

Synthesis and studies on cell-penetrating peptides.

Bioconjug Chem 2009 Jul;20(7):1307-14

Institute Gustave Roussy, CNRS UMR 8121, University Paris 11, Villejuif, France.

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http://dx.doi.org/10.1021/bc900005jDOI Listing
July 2009

Design of peptidic foldamer helices: a stereochemical patterning approach.

Angew Chem Int Ed Engl 2009 ;48(12):2171-5

Institute of Pharmaceutical Chemistry, Universitiy of Szeged, 6720 Szeged, Eötvös u. 6, Hungary.

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http://dx.doi.org/10.1002/anie.200805095DOI Listing
May 2009

Sculpting the beta-peptide foldamer H12 helix via a designed side-chain shape.

Chem Commun (Camb) 2009 Jan 14(2):177-9. Epub 2008 Nov 14.

Institute of Pharmaceutical Chemistry, University of Szeged, H-6720, Szeged, Hungary.

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http://dx.doi.org/10.1039/b812114aDOI Listing
January 2009

The Arg160Trp allele of melanocortin-1 receptor gene might protect against vitiligo.

Photochem Photobiol 2008 May-Jun;84(3):565-71. Epub 2008 Feb 11.

Dermatological Research Group of the Hungarian Academy of Sciences and the University of Szeged, Szeged, Hungary.

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http://dx.doi.org/10.1111/j.1751-1097.2008.00296.xDOI Listing
September 2008

Capillary electrophoresis tandem mass spectrometry of bromine-containing charged derivatives of peptides.

J Chromatogr A 2007 Aug 5;1159(1-2):119-24. Epub 2007 May 5.

Department of Medicinal Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.

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http://dx.doi.org/10.1016/j.chroma.2007.05.002DOI Listing
August 2007

Pituitary adenylate cyclase-activating polypeptide induces pial arteriolar vasodilation through cyclooxygenase-dependent and independent mechanisms in newborn pigs.

Brain Res 2007 Aug 27;1165:81-8. Epub 2007 Jun 27.

Department of Physiology, Faculty of Medicine, University of Szeged, 6720 Szeged, Dom ter 10, Hungary.

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http://dx.doi.org/10.1016/j.brainres.2007.06.032DOI Listing
August 2007

Synthesis of Abeta[1-42] and its derivatives with improved efficiency.

J Pept Sci 2007 Feb;13(2):94-9

Department of Medical Chemistry, University of Szeged, H-6720 Szeged, Dóm tér 8, Hungary.

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http://dx.doi.org/10.1002/psc.801DOI Listing
February 2007

Decreased serum and red blood cell kynurenic acid levels in Alzheimer's disease.

Neurochem Int 2007 Jan 4;50(2):308-13. Epub 2006 Oct 4.

Department of Psychiatry, University of Szeged, Szeged, Hungary.

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http://dx.doi.org/10.1016/j.neuint.2006.08.012DOI Listing
January 2007

Design and functional activity of phosphopeptides with potential immunomodulating capacity, based on the sequence of Grb2-associated binder 1.

Ann N Y Acad Sci 2006 Dec;1091:437-44

Department of Immunology, Eotvos Lorand University, Pazmany Peter setany 1/c, 1117 Budapest, Hungary.

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http://dx.doi.org/10.1196/annals.1378.086DOI Listing
December 2006

Effects of the alternating backbone configuration on the secondary structure and self-assembly of beta-peptides.

J Am Chem Soc 2006 Oct;128(41):13539-44

Institute of Pharmaceutical Chemistry and Department of Medical Chemistry, University of Szeged, H-6701 Szeged, POB 427, Hungary.

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http://pubs.acs.org/doi/abs/10.1021/ja063890c
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http://dx.doi.org/10.1021/ja063890cDOI Listing
October 2006

Secondary structure dependent self-assembly of beta-peptides into nanosized fibrils and membranes.

Angew Chem Int Ed Engl 2006 Apr;45(15):2396-400

Institute of Pharmaceutical Chemistry, University of Szeged, Eötvös u. 6, 6720 Szeged, Hungary.

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http://dx.doi.org/10.1002/anie.200504158DOI Listing
April 2006

Application of alicyclic beta-amino acids in peptide chemistry.

Chem Soc Rev 2006 Apr 19;35(4):323-34. Epub 2006 Jan 19.

Institute of Pharmaceutical Chemistry, University of Szeged, H-6720 Szeged, Eötvös u. 6, Hungary.

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http://dx.doi.org/10.1039/b501173fDOI Listing
April 2006

Design and performance of a sheathless capillary electrophoresis/mass spectrometry interface by combining fused-silica capillaries with gold-coated nanoelectrospray tips.

Rapid Commun Mass Spectrom 2005 ;19(7):881-5

Department of Medical Chemistry, University of Szeged, 6720 Szeged, Dóm tér 8, Hungary.

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http://dx.doi.org/10.1002/rcm.1866DOI Listing
May 2005

A peptide of human muscarinic acetylcholine receptor 3 is antigenic in primary Sjogren's syndrome.

J Autoimmun 2005 Feb 20;24(1):47-54. Epub 2005 Jan 20.

Department of Physiology, University of Szeged, Szeged, Hungary.

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http://dx.doi.org/10.1016/j.jaut.2004.11.005DOI Listing
February 2005

Chain-length-dependent helical motifs and self-association of beta-peptides with constrained side chains.

J Am Chem Soc 2005 Jan;127(2):547-53

Institute of Pharmaceutical Chemistry and Department of Medical Chemistry, University of Szeged, P.O. Box 121, H-6701 Szeged, Hungary.

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http://dx.doi.org/10.1021/ja0475095DOI Listing
January 2005

Modeling of main characteristics of bullous pemphigoid antigen-2 (BPAG2) peptide structure in serological recognition by autoantibodies.

Pathol Oncol Res 2004 18;10(1):52-6. Epub 2004 Mar 18.

Department of Immunology and Biotechnology, University of Pécs, Faculty of Medicine, Pécs, Hungary.

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http://dx.doi.org/10.1007/bf02893410DOI Listing
November 2004

A new strategy to produce beta-peptides: use of alicyclic beta-lactams.

Org Lett 2004 Nov;6(23):4239-41

Institute of Pharmaceutical Chemistry, University of Szeged, H-6720 Szeged, Eötvös u. 6, Hungary.

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http://dx.doi.org/10.1021/ol048356tDOI Listing
November 2004

Levosimendan interacts with potassium channel blockers in human saphenous veins.

Basic Clin Pharmacol Toxicol 2004 Jun;94(6):271-3

Department of Surgery, Albert Szent-Györgyi Medical Center, University of Szeged, Hungary.

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http://dx.doi.org/10.1111/j.1742-7843.2004.pto940603.xDOI Listing
June 2004

Functional consequences of a MAPK docking site on human FcgammaRIIb.

Immunol Lett 2004 Mar;92(1-2):83-90

Research Group of the Hungarian Academy of Science at the Department of Immunology, Eötvös Loránd University, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.imlet.2003.12.006DOI Listing
March 2004

cis-2-aminocyclopentanecarboxylic acid oligomers adopt a sheetlike structure: switch from helix to nonpolar strand.

Angew Chem Int Ed Engl 2002 May;41(10):1718-21

Institute of Pharmaceutical Chemistry, University of Szeged, Eötvös, 6720 Szeged, Hungary.

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http://dx.doi.org/10.1002/1521-3773(20020517)41:10<1718::aid-anie1718>3.0.co;2-2DOI Listing
May 2002