Publications by authors named "G De Palma"

816 Publications

New developments in MRI: System characterization, technical advances and radiotherapy applications.

Phys Med 2021 Sep 16;90:50-52. Epub 2021 Sep 16.

Institute of Biostructures and Bioimaging, National Research Council (CNR), 80145 Napoli, Italy.

A Special Issue of Physica Medica - European Journal of Medical Physics, focused on some important points of contact between the world of magnetic resonance and that of medical physics, was published during 2021. This Editorial describes and comments on the content of this Focus Issue, which contains articles from leading groups invited by the Guest Editors.
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http://dx.doi.org/10.1016/j.ejmp.2021.09.001DOI Listing
September 2021

Thermal evolution of Andean iron oxide-apatite (IOA) deposits as revealed by magnetite thermometry.

Sci Rep 2021 Sep 16;11(1):18424. Epub 2021 Sep 16.

Department of Earth and Environmental Sciences, University of Michigan, 1100 North University Ave, Ann Arbor, MI, USA.

Magnetite is the main constituent of iron oxide-apatite (IOA) deposits, which are a globally important source of Fe and other elements such as P and REE, critical for modern technologies. Geochemical studies of magnetite from IOA deposits have provided key insights into the ore-forming processes and source of mineralizing fluids. However, to date, only qualitative estimations have been obtained for one of the key controlling physico-chemical parameters, i.e., the temperature of magnetite formation. Here we reconstruct the thermal evolution of Andean IOA deposits by using magnetite thermometry. Our study comprised a > 3000 point geochemical dataset of magnetite from several IOA deposits within the Early Cretaceous Chilean Iron Belt, as well as from the Pliocene El Laco IOA deposit in the Chilean Altiplano. Thermometry data reveal that the deposits formed under a wide range of temperatures, from purely magmatic (~ 1000 to 800 °C), to late magmatic or magmatic-hydrothermal (~ 800 to 600 °C), to purely hydrothermal (< 600 °C) conditions. Magnetite cooling trends are consistent with genetic models invoking a combined igneous and magmatic-hydrothermal origin that involve Fe-rich fluids sourced from intermediate silicate magmas. The data demonstrate the potential of magnetite thermometry to better constrain the thermal evolution of IOA systems worldwide, and help refine the geological models used to find new resources.
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http://dx.doi.org/10.1038/s41598-021-97883-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8445919PMC
September 2021

Importance of mitigation measures for hospital transmission of SARS-CoV-2 at the onset of the epidemic: the experience of Brescia, Northern Italy.

Infection 2021 Sep 15. Epub 2021 Sep 15.

University Department of Infectious and Tropical Diseases, WHO Collaborating Centre for TB/HIV Collaborative Activities and for TB Elimination Strategy, University of Brescia, ASST Spedali Civili of Brescia, Brescia, Italy.

Purpose: Since the first Italian case of SARS-CoV-2 was detected in Lombardy (Northern Italy)  Italy quickly became one of the worst-affected European countries, with a severe impact on health-care workers (HCWs). In the first epidemic, HCWs accounted for 12% of all national COVID-19 cases. We evaluated the burden of COVID-19 among HCWs and other non-health-care workers (nHCWs) in a large Italian hospital.

Methods: From March 1st to May 31st 2020, we performed a retrospective study at ASST Civil Hospital, in the Province of Brescia, Lombardy. The study population included all hospital personnel (n = 9265), categorized by professional status.

Results: A SARS-CoV-2 test was performed in 3572 workers (38.5%), with a positive result in 552 (5.9% of all hospital personnel). The temporal trend of SARS-CoV-2 cases in hospital staff broadly reflected that in the community, with a great majority of infections occurred during March 2020 (87.7%). From April onward, a steep decrease of positive cases was observed among hospital personnel, while in the community the decrease was much slower. Medical doctors (8.9%) and nurses (8.5%) were the most affected professional categories with a significantly higher risk of SARS-CoV-2 infection (OR 1.436 and OR 1.410, respectively p < 0.0001). HCWs in COVID-19 units presented a significantly higher risk of infection compared to HCWs in non-COVID units (p < 0.001).

Conclusion: HCWs were severely affected by the COVID-19 epidemic, probably associated with an overwhelming burden of work and lack of preparedness in prevention of nosocomial transmission of the infection. The rapid decrease of COVID-19 spread in the hospital, registered before the one in the community, suggests that the adopted preventive measures were effective.
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http://dx.doi.org/10.1007/s15010-021-01692-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441227PMC
September 2021

Segmental transverse colectomy. Minimally invasive versus open approach: results from a multicenter collaborative study.

Updates Surg 2021 Sep 14. Epub 2021 Sep 14.

Department of Clinical Medicine and Surgery, Federico II University of Naples, Via Sergio Pansini, 5, 80131, Naples, Italy.

The role of minimally invasive surgery in the treatment of transverse colon cancer is still controversial. The aim of this study is to investigate the advantages of a totally laparoscopic technique comparing open versus laparoscopic/robotic approach. Three hundred and eighty-eight patients with transverse colon cancer, treated with a segmental colon resection, were retrospectively analyzed. Demographic data, tumor stage, operative time, intraoperative complications, number of harvested lymph nodes and recovery outcomes were recorded. Recurrences and death were also evaluated during the follow-up. No differences were found between conventional and minimally invasive surgery, both for oncological long-term outcomes (recurrence rate p = 0.28; mortality p = 0.62) and postoperative complications (overall rate p = 0.43; anemia p = 0.78; nausea p = 0.68; infections p = 0.91; bleeding p = 0.62; anastomotic leak p = 0.55; ileus p = 0.75). Nevertheless, recovery outcomes showed statistically significant differences in favor of minimally invasive surgery in terms of time to first flatus (p = 0.001), tolerance to solid diet (p = 0.017), time to first mobilization (p = 0.001) and hospital stay (p = 0.004). Compared with laparoscopic approach, robotic surgery showed significantly better results for time to first flatus (p = 0.001), to first mobilization (p = 0.005) and tolerance to solid diet (p = 0.001). Finally, anastomosis evaluation confirmed the superiority of intracorporeal approach which showed significantly better results for time to first flatus (p = 0.001), to first mobilization (p = 0.003) and tolerance to solid diet (p = 0.001); moreover, we recorded a statistical difference in favor of intracorporeal approach for infection rate (p = 0.04), bleeding (p = 0.001) and anastomotic leak (p = 0.03). Minimally invasive approach is safe and effective as the conventional open surgery, with comparable oncological results but not negligible advantages in terms of recovery outcomes. Moreover, we demonstrated that robotic approach may be considered a valid option and an intracorporeal anastomosis should always be preferred.
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http://dx.doi.org/10.1007/s13304-021-01159-4DOI Listing
September 2021

Laparoscopic left colic artery preserving sigmoidectomy for diverticulitis in a patient with urinary tract malformation-A Video Vignette.

Colorectal Dis 2021 Aug 28. Epub 2021 Aug 28.

Department of Clinical Medicine and Surgery, Federico II University of Naples, Naples, Italy.

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http://dx.doi.org/10.1111/codi.15892DOI Listing
August 2021
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