Fuu-Jen Tsai

Fuu-Jen Tsai

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Fuu-Jen Tsai

Publications by authors named "Fuu-Jen Tsai"

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Dystonin/BPAG1 modulates diabetes and Alzheimer's disease cross-talk: a meta-analysis.

Neurol Sci 2019 Aug 8;40(8):1577-1582. Epub 2019 Apr 8.

Department of Medical Research, China Medical University Hospital, Taichung, 40447, Taiwan.

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http://dx.doi.org/10.1007/s10072-019-03879-3DOI Listing
August 2019

Characterization of in vitro and in vivo bioactivity of a ferulic acid-2-Hydroxypropyl-β-cyclodextrin inclusion complex.

Colloids Surf B Biointerfaces 2019 Aug 20;180:68-74. Epub 2019 Apr 20.

Graduate Institute of Chinese Medicine, China Medical University, Taichung, Taiwan; School of Chinese Medicine, China Medical University, No.91 Hsueh-Shih Road, Taichung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.colsurfb.2019.04.020DOI Listing
August 2019

Protective effects and network analysis of natural compounds obtained from Radix dipsaci, Eucommiae cortex, and Rhizoma drynariae against RANKL-induced osteoclastogenesis in vitro.

J Ethnopharmacol 2019 Jul 7:112074. Epub 2019 Jul 7.

Genetic Center, Proteomics Core Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan; School of Chinese Medicine, China Medical University, Taichung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2019.112074DOI Listing
July 2019

Long-term effects of enzyme replacement therapy for Taiwanese patients with mucopolysaccharidosis IVA.

Pediatr Neonatol 2019 Jun 23;60(3):342-343. Epub 2018 Aug 23.

Department of Medicine, Mackay Medical College, New Taipei City, Taiwan; Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan; Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan; Department of Infant and Child Care, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S18759572183027
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http://dx.doi.org/10.1016/j.pedneo.2018.08.005DOI Listing
June 2019

Network analysis and mechanisms of action of Chinese herb-related natural compounds in lung cancer cells.

Phytomedicine 2019 May 13;58:152893. Epub 2019 Mar 13.

School of Chinese Medicine, China Medical University, Taichung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2019.152893DOI Listing
May 2019

Effects of Chinese herbal medicine therapy on survival and hepatic outcomes in patients with hepatitis C virus infection in Taiwan.

Phytomedicine 2019 Apr 3;57:30-38. Epub 2018 Oct 3.

School of Chinese Medicine, China Medical University, Taichung, Taiwan; Genetic Center, Proteomics Core Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2018.09.237DOI Listing
April 2019

Lupeol suppresses migration and invasion via p38/MAPK and PI3K/Akt signaling pathways in human osteosarcoma U-2 OS cells.

Biosci Biotechnol Biochem 2019 Apr 22:1-11. Epub 2019 Apr 22.

a Department of Biological Science and Technology , China Medical University , Taichung , Taiwan.

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http://dx.doi.org/10.1080/09168451.2019.1606693DOI Listing
April 2019

Congenital generalized lipodystrophy in Taiwan.

J Formos Med Assoc 2019 Jan 1;118(1 Pt 1):142-147. Epub 2018 Mar 1.

Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jfma.2018.02.003DOI Listing
January 2019

β-Sitosterol-2-hydroxypropyl-β-cyclodextrin inclusion complex: Characterization and inhibitory effect on adipogenesis in 3T3-L1 pre-adipocytes.

Steroids 2018 12 31;140:196-201. Epub 2018 Aug 31.

Graduate Institute of Chinese Medicine, China Medical University, Taichung, Taiwan; School of Chinese Medicine, China Medical University, Taichung, Taiwan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0039128X183016
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http://dx.doi.org/10.1016/j.steroids.2018.08.010DOI Listing
December 2018

Identification of Urinary Metabolite Biomarkers of Type 2 Diabetes Nephropathy Using an Untargeted Metabolomic Approach.

J Proteome Res 2018 11 15;17(11):3997-4007. Epub 2018 Oct 15.

Human Genetic Laboratory, Department of Medical Research , China Medical University Hospital , Taichung 40447 , Taiwan.

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http://dx.doi.org/10.1021/acs.jproteome.8b00644DOI Listing
November 2018

Multilocus genetic risk score for diabetic retinopathy in the Han Chinese population of Taiwan.

Sci Rep 2018 Sep 28;8(1):14535. Epub 2018 Sep 28.

Human Genetic Center, Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, 404, Taiwan.

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http://www.nature.com/articles/s41598-018-32916-y
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http://dx.doi.org/10.1038/s41598-018-32916-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162301PMC
September 2018

Novel mutations in the cartilage oligomeric matrix protein gene identified in two Taiwanese patients with pseudoachondroplasia and multiple epiphyseal dysplasia.

Pediatr Neonatol 2018 08 19;59(4):412-414. Epub 2017 Oct 19.

Department of Medical Research, China Medical University Hospital, Taichung, Taiwan; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan; School of Chinese Medicine, China Medical University, Taichung, Taiwan; Department of Medical Genetics, China Medical University Hospital, Taichung, Taiwan; Department of Health and Nutrition Biotechnology, Asia University, Taichung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.pedneo.2017.10.006DOI Listing
August 2018

Hematopoietically expressed homeobox gene is associated with type 2 diabetes in KK Cg-A/J mice and a Taiwanese Han Chinese population.

Exp Ther Med 2018 Jul 10;16(1):185-191. Epub 2018 May 10.

Human Genetics Center, Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 40447, Taiwan, R.O.C.

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http://dx.doi.org/10.3892/etm.2018.6152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995076PMC
July 2018

Identification of one novel homozygous mutation in the NPR2 gene in a patient from Taiwan with acromesomelic dysplasia Maroteaux type.

Pediatr Neonatol 2018 06 7;59(3):322-323. Epub 2017 Dec 7.

Department of Medical Research, China Medical University Hospital, Taichung, Taiwan; Division of Genetics and Metabolism, Children's Hospital of China Medical University, Taichung, Taiwan; School of Chinese Medicine, China Medical University, Taichung, Taiwan; Department of Medical Genetics, China Medical University Hospital, Taichung, Taiwan; Department of Health and Nutrition Biotechnology, Asia University, Taichung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.pedneo.2017.11.017DOI Listing
June 2018

Effects of Chinese herbal medicine on hyperlipidemia and the risk of cardiovascular disease in HIV-infected patients in Taiwan.

J Ethnopharmacol 2018 Jun 10;219:71-80. Epub 2018 Mar 10.

School of Chinese Medicine, China Medical University, Taichung, Taiwan; Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2018.03.006DOI Listing
June 2018

A water-based topical Chinese traditional medicine (Zicao) for wound healing developed using 2-hydroxypropyl-β-cyclodextrin.

Colloids Surf B Biointerfaces 2018 May 10;165:67-73. Epub 2018 Feb 10.

Graduate Institute of Chinese Medicine, China Medical University, Taichung, Taiwan; School of Chinese Medicine, China Medical University, Taichung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.colsurfb.2018.02.013DOI Listing
May 2018

Kaempferol inhibits angiogenic ability by targeting VEGF receptor-2 and downregulating the PI3K/AKT, MEK and ERK pathways in VEGF-stimulated human umbilical vein endothelial cells.

Oncol Rep 2018 May 14;39(5):2351-2357. Epub 2018 Mar 14.

Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 40447, Taiwan, R.O.C.

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http://dx.doi.org/10.3892/or.2018.6312DOI Listing
May 2018

A novel PIGA mutation in a Taiwanese family with early-onset epileptic encephalopathy.

Seizure 2018 May 7;58:52-54. Epub 2018 Apr 7.

Division of Pediatrics Neurology, China Medical University, Children's Hospital, Taichung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.seizure.2018.03.025DOI Listing
May 2018

Inhibition of HSF2 SUMOylation via MEL18 upregulates IGF-IIR and leads to hypertension-induced cardiac hypertrophy.

Int J Cardiol 2018 04 10;257:283-290. Epub 2017 Nov 10.

School of Chinese Medicine, China Medical University, Taichung, Taiwan; Graduate Institute of Basic Medical Science, China Medical University, Taichung, Taiwan; Department of Health and Nutrition Biotechnology, Asia University, Taichung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.10.102DOI Listing
April 2018

Relaxant and vasoprotective effects of ginger extracts on porcine coronary arteries.

Int J Mol Med 2018 Apr 11;41(4):2420-2428. Epub 2018 Jan 11.

Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 40447, Taiwan, R.O.C.

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http://dx.doi.org/10.3892/ijmm.2018.3380DOI Listing
April 2018

Characteristics of Chinese herbal medicine usage and its effect on survival of lung cancer patients in Taiwan.

J Ethnopharmacol 2018 Mar 31;213:92-100. Epub 2017 Oct 31.

School of Chinese Medicine, China Medical University, Taichung, Taiwan; Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2017.10.031DOI Listing
March 2018

2-Phenyl-4-quinolone (YT-1) induces G2/M phase arrest and an intrinsic apoptotic mechanism in human leukemia cells.

Oncol Rep 2018 Mar 20;39(3):1331-1337. Epub 2017 Dec 20.

Department of Biochemistry, China Medical University, Taichung 404, Taiwan, R.O.C.

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http://dx.doi.org/10.3892/or.2017.6170DOI Listing
March 2018

The molecular mechanism of contrast-induced nephropathy (CIN) and its link to in vitro studies on iodinated contrast media (CM).

Biomedicine (Taipei) 2018 Mar 26;8(1). Epub 2018 Feb 26.

Genetics Center, Department of Medical Research, China Medical University Hospital, Taichung 404, Taiwan - School of Chinese Medicine, China Medical University, Taichung 404, Taiwan - Department of Medical Genetics, China Medical University Hospital, Taichung 404, Taiwan.

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http://dx.doi.org/10.1051/bmdcn/2018080101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826038PMC
March 2018

Late onset of biliopleural fistula following percutaneous transhepatic biliary drainage: a case report.

Biomedicine (Taipei) 2018 Mar 26;8(1). Epub 2018 Feb 26.

Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 404, Taiwan.

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http://dx.doi.org/10.1051/bmdcn/2018080106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826039PMC
March 2018

Matrix metalloproteinase 14 modulates diabetes and Alzheimer's disease cross-talk: a meta-analysis.

Neurol Sci 2018 Feb 4;39(2):267-274. Epub 2017 Nov 4.

Department of Medical Research, China Medical University Hospital, Taichung, 40447, Taiwan.

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http://dx.doi.org/10.1007/s10072-017-3166-4DOI Listing
February 2018

ITR‑284 modulates cell differentiation in human chronic myelogenous leukemia K562 cells.

Oncol Rep 2018 Jan 9;39(1):383-391. Epub 2017 Nov 9.

Department of Biological Science and Technology, China Medical University, Taichung, Taiwan, R.O.C.

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http://dx.doi.org/10.3892/or.2017.6090DOI Listing
January 2018

The differential regulation of microRNAs is associated with oral cancer.

Oncol Rep 2017 Sep 12;38(3):1613-1620. Epub 2017 Jul 12.

Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan, R.O.C.

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http://dx.doi.org/10.3892/or.2017.5811DOI Listing
September 2017

Autophagy and its link to type II diabetes mellitus.

Biomedicine (Taipei) 2017 Jun 14;7(2). Epub 2017 Jun 14.

Genetics Center, Department of Medical Research, China Medical University Hospital, Taichung 404, Taiwan - School of Chinese Medicine, China Medical University, Taichung 404, Taiwan - Department of Medical Genetics, China Medical University Hospital, China Medical University, Taichung 404, Taiwan.

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http://dx.doi.org/10.1051/bmdcn/2017070201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479440PMC
June 2017

YC-1 induces G/G phase arrest and mitochondria-dependent apoptosis in cisplatin-resistant human oral cancer CAR cells.

Biomedicine (Taipei) 2017 Jun 14;7(2):12. Epub 2017 Jun 14.

Genetics Center, Department of Medical Research, China Medical University Hospital, Taichung 404, Taiwan - School of Chinese Medicine, China Medical University, Taichung 404, Taiwan - Department of Medical Genetics, China Medical University Hospital, Taichung 404, Taiwan.

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http://dx.doi.org/10.1051/bmdcn/2017070205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479426PMC
June 2017

Filamin B Loss-of-Function Mutation in Dimerization Domain Causes Autosomal-Recessive Spondylocarpotarsal Synostosis Syndrome with Rib Anomalies.

Hum Mutat 2017 05 27;38(5):540-547. Epub 2017 Feb 27.

Department of Medical Genetics, China Medical University Hospital, Taichung, Taiwan.

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http://dx.doi.org/10.1002/humu.23186DOI Listing
May 2017

Genetic epidemiological study doesn't support GLA IVS4+919G>A variant is a significant mutation in Fabry disease.

Mol Genet Metab 2017 05 24;121(1):22-27. Epub 2017 Mar 24.

Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Graduate Institute of Chinese Medical Science, China Medical University, Taichung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2017.03.005DOI Listing
May 2017

Genome-Wide Association Study Meta-Analysis of Long-Term Average Blood Pressure in East Asians.

Circ Cardiovasc Genet 2017 Apr;10(2):e001527

From the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA (C.L., J.H., J.Z., T.N.K.); Center for Genome Science, Korea National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Korea (Y.K.K., J.L., S.H., B.-G.H., S.M., B.-J.K.); Genome Institute of Singapore, Agency for Science, Technology and Research (R.D., J.L., Y.-Y.T.); Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Graduate University of the Chinese Academy of Sciences (H.L., Y.H., Y.W., L.S., X.L.); National Yang-Ming University Hospital, Taipei, Taiwan (I-T.L.); National Yang-Ming University Hospital, Taipei, Taiwan; Singapore Eye Research Institute, Singapore National Eye Center (Y.C., Y.K., Y.Z., N.K., T.Y.W.); Duke-NUS Graduate Medical School, National University of Singapore, (Y.C., N.K., T.Y.W., E-S.T.); Department of Ophthalmology (Y.C., T.Y.W.), Department of Statistics and Applied Probability (Y.-Y.T.), Life Sciences Institute (Y.-Y.T.), NUS Graduate School for Integrative Science and Engineering (Y.-Y.T.), Department of Medicine, National University Health System, Singapore (E-S.T.); MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China (M.H., H.H., L.G., Y.H., T.W.); Division of Endocrine and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taipei, Taiwan (I-T.L., W.H-h.S); School of Medicine, National Yang-Ming University, Taipei, Taiwan (W.H-h.S., K.-W.L.); Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA (X.G., J.Y., K.D.T., J.I.R., Y.-d.I.C.); Division of Cardiovascular Medicine, Department of Internal Medicine, Department of Human Genetics, University of Michigan, Ann Arbor (S.K.G.); Department of Medicine, Tulane University School of Medicine, New Orleans, LA (J.H., J.C.); Saw Swee Hock School of Public Health, National University of Singapore and National University Health System (J.L., Y.-Y.T., X.S., E-S.T.); Division of Biostatistics, Washington University School of Medicine, St. Louis, MO (D.C.R.); Department of Medical Genetics (F.-J.T.) and School of Chinese Medicine (C.-H.C., J.-Y.W.), China Medical University Hospital, Taichung, Taiwan; Department of Medicine, Columbia University Medical Center, New York, NY (W.P.); Department of Epidemiology, Human Genetics and Environmental Sciences, University of Texas School of Public Health, Houston (J.E.H.); Department of Internal Medicine, Ditmanson Medical Foundation, Chiayi Christian Hospital, Taiwan (C.H.L.); Department of Business Administration, National Chung Cheng University, Chia-yi, Taiwan (C.H.L.); Department of Nursing, DaYeh University, Changhua, Taiwan (C.H.L.); Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan (W.-J.L.); State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (D.G.); National Center for Genome Medicine, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan (C.-H.C., J.-Y.W.); Department of Ophthalmology and Visual Science, Khoo Teck Puat Hospital, Singapore, Singapore (N.K.); Medical Genetics Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA (L.J.R.); and Department of Epidemiology and Biostatistics, University of Georgia at Athens, Athens (C.L.); Department of Cardiovascular Center, Taichung Veterans General Hospital, Taichung, Taiwan (K.-W.L.).

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http://dx.doi.org/10.1161/CIRCGENETICS.116.001527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704911PMC
April 2017

Carboxamide analog ITR-284 evokes apoptosis and inhibits migration ability in human lung adenocarcinoma A549 cells.

Oncol Rep 2017 Mar 16;37(3):1786-1792. Epub 2017 Jan 16.

Department of Biological Science and Technology, China Medical University, Taichung 40402, Taiwan, R.O.C.

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http://dx.doi.org/10.3892/or.2017.5374DOI Listing
March 2017

Resveratrol-induced autophagy and apoptosis in cisplatin-resistant human oral cancer CAR cells: A key role of AMPK and Akt/mTOR signaling.

Int J Oncol 2017 Mar 30;50(3):873-882. Epub 2017 Jan 30.

School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 110, Taiwan, R.O.C.

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http://dx.doi.org/10.3892/ijo.2017.3866DOI Listing
March 2017

Effect of Chinese herbal medicine on stroke patients with type 2 diabetes.

J Ethnopharmacol 2017 Mar 16;200:31-44. Epub 2017 Feb 16.

School of Chinese Medicine, China Medical University, Taichung, Taiwan; Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2017.02.024DOI Listing
March 2017

Molecular pathways related to the longevity promotion and cognitive improvement of Cistanche tubulosa in Drosophila.

Phytomedicine 2017 Mar 17;26:37-44. Epub 2017 Jan 17.

Graduate Institute of Acupuncture Science, China Medical University, Taichung, Taiwan; Department of Bioinformatics and Medical Engineering, Asia University, Taichung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.phymed.2017.01.006DOI Listing
March 2017

H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis.

Nat Commun 2017 03 16;8:14799. Epub 2017 Mar 16.

Department of Cancer Biology, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157, USA.

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http://dx.doi.org/10.1038/ncomms14799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357315PMC
March 2017

Qi deficiency is associated with depression in chronic hemodialysis patients.

Complement Ther Med 2017 Feb 28;30:102-106. Epub 2016 Dec 28.

Department of Chinese Medicine, China Medical University Hospital, Taichung 404, Taiwan; School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung 404, Taiwan; Research Center for Chinese Medicine & Acupuncture, China Medical University, Taichung, 404, Taiwan; Research Center for Traditional Chinese Medicine, Department of Medical Research and Department of Chinese Medicine, China Medical University Hospital, Taichung 404, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ctim.2016.12.008DOI Listing
February 2017

Polymorphism and protein expression of MUTYH gene for risk of rheumatoid arthritis.

BMC Musculoskelet Disord 2017 02 7;18(1):69. Epub 2017 Feb 7.

Genetics Center, Department of Medical Research, China Medical University Hospital, Taichung, 404, Taiwan.

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http://bmcmusculoskeletdisord.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/s12891-017-1437-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297156PMC
February 2017

Transformation of 5-D itch scale and numerical rating scale in chronic hemodialysis patients.

BMC Nephrol 2017 02 8;18(1):56. Epub 2017 Feb 8.

Kidney Institute and Division of Nephrology, China Medical University Hospital, No. 2, Yu-der Road, North District, Taichung, 40447, Taiwan.

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http://dx.doi.org/10.1186/s12882-017-0475-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299664PMC
February 2017

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.

Authors:
Frank J A van Rooij Rehan Qayyum Albert V Smith Yi Zhou Stella Trompet Toshiko Tanaka Margaux F Keller Li-Ching Chang Helena Schmidt Min-Lee Yang Ming-Huei Chen James Hayes Andrew D Johnson Lisa R Yanek Christian Mueller Leslie Lange James S Floyd Mohsen Ghanbari Alan B Zonderman J Wouter Jukema Albert Hofman Cornelia M van Duijn Karl C Desch Yasaman Saba Ayse B Ozel Beverly M Snively Jer-Yuarn Wu Reinhold Schmidt Myriam Fornage Robert J Klein Caroline S Fox Koichi Matsuda Naoyuki Kamatani Philipp S Wild David J Stott Ian Ford P Eline Slagboom Jaden Yang Audrey Y Chu Amy J Lambert André G Uitterlinden Oscar H Franco Edith Hofer David Ginsburg Bella Hu Brendan Keating Ursula M Schick Jennifer A Brody Jun Z Li Zhao Chen Tanja Zeller Jack M Guralnik Daniel I Chasman Luanne L Peters Michiaki Kubo Diane M Becker Jin Li Gudny Eiriksdottir Jerome I Rotter Daniel Levy Vera Grossmann Kushang V Patel Chien-Hsiun Chen Paul M Ridker Hua Tang Lenore J Launer Kenneth M Rice Ruifang Li-Gao Luigi Ferrucci Michelle K Evans Avik Choudhuri Eirini Trompouki Brian J Abraham Song Yang Atsushi Takahashi Yoichiro Kamatani Charles Kooperberg Tamara B Harris Sun Ha Jee Josef Coresh Fuu-Jen Tsai Dan L Longo Yuan-Tsong Chen Janine F Felix Qiong Yang Bruce M Psaty Eric Boerwinkle Lewis C Becker Dennis O Mook-Kanamori James G Wilson Vilmundur Gudnason Christopher J O'Donnell Abbas Dehghan L Adrienne Cupples Michael A Nalls Andrew P Morris Yukinori Okada Alexander P Reiner Leonard I Zon Santhi K Ganesh

Am J Hum Genet 2017 Jan 22;100(1):51-63. Epub 2016 Dec 22.

Division of Cardiovascular Medicine, Department of Internal Medicine, Department of Human Genetics, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI 48109, USA. Electronic address:

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http://www.cell.com/ajhg/pdf/S0002-9297(16)30520-1.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S000292971630520
Publisher Site
http://dx.doi.org/10.1016/j.ajhg.2016.11.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223059PMC
January 2017

Gadolinium chloride elicits apoptosis in human osteosarcoma U-2 OS cells through extrinsic signaling, intrinsic pathway and endoplasmic reticulum stress.

Oncol Rep 2016 Dec 14;36(6):3421-3426. Epub 2016 Oct 14.

Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan, R.O.C.

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http://dx.doi.org/10.3892/or.2016.5174DOI Listing
December 2016

A case of Pitt-Hopkins syndrome presented with Angelman-like syndromic phenotypes.

Biomedicine (Taipei) 2016 Dec 19;6(4):25. Epub 2016 Nov 19.

Department of Pediatrics, Children's Hospital, China Medical University Hospital, Taichung, 404, Taiwan.

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http://dx.doi.org/10.7603/s40681-016-0025-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147553PMC
December 2016

TRAF6 Restricts p53 Mitochondrial Translocation, Apoptosis, and Tumor Suppression.

Mol Cell 2016 11 3;64(4):803-814. Epub 2016 Nov 3.

Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Graduate Institute of Basic Medical Science, China Medical University, Taichung 404, Taiwan; Department of Biotechnology, Asia University, Taichung 41354, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541903PMC
November 2016

CCY-1a-E2 induces G2/M phase arrest and apoptotic cell death in HL-60 leukemia cells through cyclin-dependent kinase 1 signaling and the mitochondria-dependent caspase pathway.

Oncol Rep 2016 Sep 25;36(3):1633-9. Epub 2016 Jul 25.

Department of Biochemistry, China Medical University, Taichung 404, Taiwan, R.O.C.

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http://dx.doi.org/10.3892/or.2016.4970DOI Listing
September 2016

3-O-methyldopa levels in newborns: Result of newborn screening for aromatic l-amino-acid decarboxylase deficiency.

Mol Genet Metab 2016 08 16;118(4):259-63. Epub 2016 May 16.

Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1016/j.ymgme.2016.05.011DOI Listing
August 2016

Risk of epilepsy in type 1 diabetes mellitus: a population-based cohort study.

Diabetologia 2016 06 31;59(6):1196-203. Epub 2016 Mar 31.

Graduate Institute of Clinical Medical Science and School of Medicine, College of Medicine, China Medical University, No. 2, Yuh-Der Road, Taichung, 40447, Taiwan.

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http://www.diabetologia-journal.org/files/Chou.pdf
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http://link.springer.com/10.1007/s00125-016-3929-0
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http://dx.doi.org/10.1007/s00125-016-3929-0DOI Listing
June 2016

Long-term galsulfase enzyme replacement therapy in Taiwanese mucopolysaccharidosis VI patients: A case series.

Mol Genet Metab Rep 2016 06 18;7:63-9. Epub 2016 Apr 18.

Department of Medicine, Mackay Medical College, New Taipei City, Taiwan; Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan; Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan; Department of Infant and Child Care, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.

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http://dx.doi.org/10.1016/j.ymgmr.2016.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834679PMC
June 2016

Current concepts regarding developmental mechanisms in diabetic retinopathy in Taiwan.

Biomedicine (Taipei) 2016 Jun 5;6(2). Epub 2016 May 5.

Genetics Center, Department of Medical Research, China Medical University Hospital, No. 2 Yuh Der Road, 404, Taichung, Taiwan.

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http://dx.doi.org/10.7603/s40681-016-0007-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859317PMC
June 2016

Marked improvement in febrile infection-related epilepsy syndrome after lidocaine plus MgSO4 treatment in a 12-year-old girl.

Epilepsy Behav Case Rep 2016 2;6:6-9. Epub 2016 Jun 2.

Division of Pediatric Neurology, Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan; Institute of Medicine, School of Medicine, Chung Shan Medical University, Taichung, Taiwan.

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http://dx.doi.org/10.1016/j.ebcr.2016.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917485PMC
June 2016

Inhibition of DNA methyltransferase 1 increases nuclear receptor subfamily 4 group A member 1 expression and decreases blood glucose in type 2 diabetes.

Oncotarget 2016 Jun;7(26):39162-39170

Human Genetic Center, Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan.

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http://dx.doi.org/10.18632/oncotarget.10043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129922PMC
June 2016

Kaempferol induces ATM/p53-mediated death receptor and mitochondrial apoptosis in human umbilical vein endothelial cells.

Int J Oncol 2016 May 4;48(5):2007-14. Epub 2016 Mar 4.

Department of Pharmacy and Master Program, Tajen University, Pingtung, Taiwan, R.O.C.

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http://dx.doi.org/10.3892/ijo.2016.3420DOI Listing
May 2016

Identification and Characterization of Mutations in the CLCN7 Gene in a Taiwanese Patient with Infantile Malignant Osteopetrosis.

Pediatr Neonatol 2016 Apr 13;57(2):155-7. Epub 2015 Aug 13.

Department of Medical Research, China Medical University Hospital, Taichung, Taiwan; Department of Genetics and Metabolism, Children's Hospital of China Medical University, Taichung, Taiwan; School of Chinese Medicine, China Medical University, Taichung, Taiwan; Department of Medical Genetics, China Medical University Hospital, Taichung, Taiwan; Department of Health and Nutrition Biotechnology, Asia University, Taichung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.pedneo.2015.04.013DOI Listing
April 2016

Cardiac structure and function and effects of enzyme replacement therapy in patients with mucopolysaccharidoses I, II, IVA and VI.

Mol Genet Metab 2016 Apr 16;117(4):431-7. Epub 2016 Feb 16.

Department of Medicine, Mackay Medical College, New Taipei City, Taiwan; Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan; Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan; Department of Infant and Child Care, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2016.02.003DOI Listing
April 2016

Rapid fabrication of functionalized plates for peptides, glycopeptides and protein purification and mass spectrometry analysis.

Analyst 2016 Apr;141(7):2183-90

Proteomics Core Laboratory, Department of Medical Research, China Medical University Hospital, Taichung 40402, Taiwan. and Graduate Institute of Integrated Medicine, China Medical University, Taichung 40402, Taiwan.

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http://dx.doi.org/10.1039/c6an00113kDOI Listing
April 2016

AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation.

Cancer Res 2016 Mar 12;76(6):1451-62. Epub 2016 Jan 12.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Center for Molecular Medicine and Graduate Institute of Cancer Biology, China Medical University, Taichung, Taiwan. Department of Biotechnology, Asia University, Taichung, Taiwan. Graduate School of Biomedical Sciences, The University of Texas Health Science Center, Houston, Texas.

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http://cancerres.aacrjournals.org/content/early/2016/01/12/0
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http://cancerres.aacrjournals.org/content/early/2016/01/12/0
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http://cancerres.aacrjournals.org/content/early/2016/03/03/0
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-15-1941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794388PMC
March 2016