Publications by authors named "Fu-Qiang Huang"

14 Publications

  • Page 1 of 1

A New Segmented Virus Associated with Human Febrile Illness in China.

N Engl J Med 2019 05;380(22):2116-2125

From the School of Life Sciences and Engineering, Foshan University, Foshan, Guangdong Province (Z.-D.W., Z.-T.Y., H.-J.Z., S.-J.H., J.C., F.-Q.H., Q.L.), the Military Veterinary Institute, Academy of Military Medical Sciences, Changchun, Jilin Province (Z.-D.W., L.L., S.-C.W., Q.L.), MOA Key Laboratory of Animal Virology and Department of Veterinary Medicine, Zhejiang University, Hangzhou, Zhejiang Province (Z.-D.W., Y.Y., J.H., Y.-L.J., J.-Y.Z.), the Second Affiliated Hospital of Inner Mongolia University for the Nationalities, Inner Mongolia General Forestry Hospital, Yakeshi, Inner Mongolia Autonomous Region (B.W., S.-Z.H., X.-L.L., W.W.), the College of Life Science, Jilin Agricultural University, Changchun, Jilin Province (F.W., L.Z., S.L., H.-H.L.), the College of Veterinary Medicine, Northeast Agricultural University, Harbin, Heilongjiang Province (M.-X.S.), and the Department of Experimental Pathology, Institute of Radiation Medicine, Beijing (B.W.) - all in China.

Background: In 2017, surveillance for tickborne diseases in China led to the identification of a patient who presented to a hospital in Inner Mongolia with a febrile illness that had an unknown cause. The clinical manifestation of the illness was similar to that of tickborne encephalitis virus (TBEV) infection, but neither TBEV RNA nor antibodies against the virus were detected.

Methods: We obtained a blood specimen from the index patient and attempted to isolate and identify a causative pathogen, using genome sequence analysis and electron microscopy. We also initiated a heightened surveillance program in the same hospital to screen for other patients who presented with fever, headache, and a history of tick bites. We used reverse-transcriptase-polymerase-chain-reaction (RT-PCR) and cell-culture assays to detect the pathogen and immunofluorescence and neutralization assays to determine the levels of virus-specific antibodies in serum specimens from the patients.

Results: We found that the index patient was infected with a previously unknown segmented RNA virus, which we designated Alongshan virus (ALSV) and which belongs to the jingmenvirus group of the family Flaviviridae. ALSV infection was confirmed by RT-PCR assay in 86 patients from Inner Mongolia and Heilongjiang who presented with fever, headache, and a history of tick bites. Serologic assays showed that seroconversion had occurred in all 19 patients for whom specimens were available from the acute phase and the convalescent phase of the illness.

Conclusions: A newly discovered segmented virus was found to be associated with a febrile illness in northeastern China. (Funded by the National Key Research and Development Program of China and the National Natural Science Foundation of China.).
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http://dx.doi.org/10.1056/NEJMoa1805068DOI Listing
May 2019

Impacts of climate change and human activities on grassland vegetation variation in the Chinese Loess Plateau.

Sci Total Environ 2019 Apr 4;660:236-244. Epub 2019 Jan 4.

State Key Laboratory of Grassland Agro-ecosystems, Institute of Arid Agroecology, School of Life Sciences, Lanzhou University, No. 222, South Tianshui Road, Lanzhou 730000, China. Electronic address:

China initiated the "Grain for Green Project" in 1999 to mitigate soil erosion. The vegetation cover of the Chinese Loess Plateau, one of the most erosive regions in the world, has been greatly increased. However, studies on quantitatively investigating the climate change and human activities on vegetation coverage change were rare. In this study, spatio-temporal changes in vegetation coverage were investigated using MODIS normalized difference vegetation index (NDVI) data over 2000-2016. And a new method was introduced using Net Primary Productivity (NPP) model and relationship between NPP and NDVI to quantitatively and spatially distinguish the NDVI affected by climate change and human activities. Results showed that mean NDVI value over 2009-2016 were 14.46% greater than that over 2000-2007. In order to quantify the contribution of climate change and human activities to vegetation change, an NPP model suitable for the grassland of the Chinese Loess Plateau was identified using biomass observations from field survey and literature. The NDVI affected by climate change (NDVI) was estimated by the NPP model and the relationship between NPP and NDVI. And the NDVI affected by human activities (NDVI) was calculated by actual NDVI minus NDVI. Comparison of the two stages showed that human activities and climate change contributed 42.35% and 57.65% respectively to the ΔNDVI on grassland in the Loess Plateau. After analysis of numerous NDVI related factors, the slopes restored by the "Grain for Green Project" was considered the main influence factor of human activities.
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http://dx.doi.org/10.1016/j.scitotenv.2019.01.022DOI Listing
April 2019

Dehydrogenation of Formic Acid at Room Temperature: Boosting Palladium Nanoparticle Efficiency by Coupling with Pyridinic-Nitrogen-Doped Carbon.

Angew Chem Int Ed Engl 2016 09 23;55(39):11849-53. Epub 2016 Aug 23.

Department of Chemistry, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Collaborative Innovation Center of Chemistry for Energy Materials, Fudan University, Shanghai, 200433, P.R. China.

The use of formic acid (FA) to produce molecular H2 is a promising means of efficient energy storage in a fuel-cell-based hydrogen economy. To date, there has been a lack of heterogeneous catalyst systems that are sufficiently active, selective, and stable for clean H2 production by FA decomposition at room temperature. For the first time, we report that flexible pyridinic-N-doped carbon hybrids as support materials can significantly boost the efficiency of palladium nanoparticle for H2 generation; this is due to prominent surface electronic modulation. Under mild conditions, the optimized engineered Pd/CN0.25 catalyst exhibited high performance in both FA dehydrogenation (achieving almost full conversion, and a turnover frequency of 5530 h(-1) at 25 °C) and the reversible process of CO2 hydrogenation into FA. This system can lead to a full carbon-neutral energy cycle.
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http://dx.doi.org/10.1002/anie.201605961DOI Listing
September 2016

Antiperovskite Chalco-Halides Ba3(FeS4)Cl, Ba3(FeS4)Br, and Ba3(FeSe4)Br with Spin Super-Super Exchange.

Sci Rep 2015 Nov 3;5:15910. Epub 2015 Nov 3.

Beijing National Laboratory for Molecular Sciences and State Key Laboratory of Rare Earth Materials Chemistry and Applications, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.

Perovskite-related materials have received increasing attention for their broad applications in photovoltaic solar cells and information technology due to their unique electrical and magnetic properties. Here we report three new antiperovskite chalco-halides: Ba3(FeS4)Cl, Ba3(FeS4)Br, and Ba3(FeSe4)Br. All of them were found to be good solar light absorbers. Remarkably, although the shortest Fe-Fe distance exceeds 6 Å, an unexpected anti-ferromagnetic phase transition near 100 K was observed in their magnetic susceptibility measurement. The corresponding complex magnetic structures were resolved by neutron diffraction experiments as well as investigated by first-principles electronic structure calculations. The spin-spin coupling between two neighboring Fe atoms along the b axis, which is realized by the Fe-S···S-Fe super-super exchange mechanism, was found to be responsible for this magnetic phase transition.
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http://dx.doi.org/10.1038/srep15910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630630PMC
November 2015

[Species identification of Echinococcus isolates collected from canines and Tibetan foxes in Chengduo County, Qinghai Province].

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 2013 Jun;31(3):185-7

Objective: To identify Echinococcus isolates collected from Tibetan foxes(Vulpes ferrilata) and dogs in Chengduo county, Yushu Prefecture, Qinghai Province.

Methods: Six Tibetan foxes and 6 Tibetan dogs died accidently. Small intestines were dissected from the animals. The adult tap-worms were collected by sedimentation technique. The worms were stained with borax carmine and observed under microscope. The isolates were identified initially by morphology and the infection intensity for each animal was calculated. Eight isolates of E. multilocularis and 2 isolates of E. shiquicus were selected for the extraction of total DNA. The mitochondrion DNA CO I gene was amplified with specific primers by PCR, then sequenced and analyzed.

Results: E. multilocularis and E. shiquicus were found. Two out of 6 Tibetan foxes were infected with E. multilocularis, the infection intensity was 1,640 and 839. One Tibetan fox was infected by E. shiquicus with an infection intensity of 833. Two Tibetan dogs were infected with E. multilocularis, and the infection intensity was 10,195 and 78, respectively. The obtained partial sequences of CO I gene were 450 bp. The CO I gene from 8 isolates of E. multilocularis shared 100% homology with the isolates collected from Tibetan dogs in Sichuan Province (Accession No. AB461417). The CO I gene from 2 isolates of E. shiquicus showed high sequence homology (99.2%) with the isolates collected from Ochotona curzoniae in Shiqu County, Sichuan Province(Accession No. AB159136).

Conclusion: E. multilocularis and E. shiquicus have been identified in the small intestines of wild foxes, and E. multilocularis in Tibetan dogs.
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June 2013

Low-temperature rapid synthesis and superconductivity of Fe-based oxypnictide superconductors.

J Am Chem Soc 2010 Mar;132(10):3260-1

CAS Key Laboratory of Materials for Energy Conversion, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, PR China.

Fe-based oxypnictide superconductors were successfully synthesized at lower reaction temperatures and with shorter reaction times made possible by starting with less stable compounds, which provide a larger driving force for reactions. Using ball-milled powders of intermediate compounds, phase-pure superconductors with T(c) above 50 K were synthesized at 1173 K in 20 min. This method is particularly advantageous for retaining F, a volatile dopant that enhances superconductivity. Bulk superconductivity and high upper critical fields up to 392 T in Sm(0.85)Nd(0.15)FeAsO(0.85)F(0.15) were demonstrated.
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http://dx.doi.org/10.1021/ja100055kDOI Listing
March 2010

Syntheses, crystal structures, and physical properties of La5Cu6O4S7 and La5Cu6.33O4S7.

Inorg Chem 2008 May 23;47(10):4368-74. Epub 2008 Apr 23.

Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208-3113, USA.

Single crystal and bulk powder samples of the quaternary lanthanum copper oxysulfides La5Cu6.33O4S7 and La5Cu6O4S7 have been prepared by means of high-temperature sealed-tube reactions and spark plasma sintering, respectively. In the structure of La 5Cu6.33O4S7, Cu atoms tie together the fluorite-like (2)infinity[La5O4S(5+)] and antifluorite-like (2) infinity[Cu6S6(5-)] layers of La5Cu6O4S7. The optical band gap, E g, of 2.0 eV was deduced from both diffuse reflectance spectra on a bulk sample of La5Cu6O4S7 and for the (010) crystal face of a La 5Cu6.33O4S7 single crystal. Transport measurements at 298 K on a bulk sample of La 5Cu 6O 4S 7 indicated p-type metallic electrical conduction with sigma electrical =2.18 S cm(-1), whereas measurements on a La 5Cu6.33O4S7 single crystal led to sigma electrical =4.5 10(-3) S cm(-1) along [100] and to semiconducting behavior. In going from La 5Cu6O4S7 to La5Cu6.33O4S7, the disruption of the (2)infinity[Cu6S6(5-)] layer and the decrease in the overall Cu(2+)(3d(9)) concentration lead to a significant decrease in the electrical conductivity.
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http://dx.doi.org/10.1021/ic7024796DOI Listing
May 2008

Structures and bonding in K0.91U1.79S6 and KU2Se6.

Inorg Chem 2006 Apr;45(8):3307-11

Department of Chemistry, Northwestern University, Evanston, Illinois 60208, USA.

The compounds K0.91U1.79S6 and KU2Se6, members of the AAn2Q6 actinide family (A = alkali metal or Tl; An = Th or U; Q = S, Se, or Te), have been synthesized from US2, K2S, and S at 1273 K and U, K2Se, and Se at 1173 K, respectively. KU2Se6 shows Curie-Weiss behavior above 30 K and no magnetic ordering down to 5 K. The value of mu(eff) is 2.95(1) mu(B)/U. Its electronic spectrum shows the peaks characteristic of 5f-5f transitions. It is a semiconductor with an activation energy of 0.27 eV for electrical conduction. Both K0.91U1.79S6 and KU2Se6 crystallize in space group Immm of the orthorhombic system and are of the KTh2Se6 structure type. Both contain infinite one-dimensional linear Q-Q chains characteristic of the AAn2Q6 family. Typical of the known AAn2Q6 compounds, in KU2Se6, there are two alternating Se-Se distances of 2.703(2) and 2.855(2) A, both much longer than an Se-Se single bond. In contrast, in K0.91U1.79S6, the first sulfide of this family to be characterized structurally, there are alternating normal S2(2-) pairs 2.097(5) A in length. In K0.91U1.79S6, the formal oxidation state of U is 4+.
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http://dx.doi.org/10.1021/ic052140lDOI Listing
April 2006

Syntheses, structure, and selected physical properties of CsLnMnSe3 (Ln = Sm, Gd, Tb, Dy, Ho, Er, Tm, Yb, Y) and AYbZnQ3 (A = Rb, Cs; Q = S, Se, Te).

Inorg Chem 2004 Feb;43(3):1082-9

Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, USA.

CsLnMnSe(3) (Ln = Sm, Gd, Tb, Dy, Ho, Er, Tm, Yb, Y) and AYbZnQ(3) (A = Rb, Cs; Q = S, Se, Te) have been synthesized from solid-state reactions at temperatures in excess 1173 K. These isostructural materials crystallize in the layered KZrCuS(3) structure type in the orthorhombic space group Cmcm. The structure is composed of LnQ(6) octahedra and MQ(4) tetrahedra that share edges to form [LnMQ(3)] layers. These layers stack perpendicular to [010] and are separated by layers of face- and edge-sharing AQ(8) bicapped trigonal prisms. There are no Q-Q bonds in the structure of the ALnMQ(3) compounds so the formal oxidation states of A/Ln/M/Q are 1+/3+/2+/2-. The CsLnMnSe(3) materials, with the exception of CsYbMnSe(3), are Curie-Weiss paramagnets between 5 and 300 K. The magnetic susceptibility data for CsYbZnS(3), RbYbZnSe(3), and CsYbMSe(3) (M = Mn, Zn) show a weak cusp at approximately 10 K and pronounced differences between field-cooled and zero-field-cooled data. However, CsYbZnSe(3) is not an antiferromagnet because a neutron diffraction study indicates that CsYbZnSe(3) shows neither long-range magnetic ordering nor a phase change between 4 and 295 K. Nor is the compound a spin glass because the transition at 10 K does not depend on ac frequency. The optical band gaps of the (010) and (001) crystal faces for CsYbMnSe(3) are 1.60 and 1.59 eV, respectively; the optical band of the (010) crystal faces for CsYbZnS(3) and RbYbZnSe(3) are 2.61 and 2.07 eV, respectively.
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http://dx.doi.org/10.1021/ic030232+DOI Listing
February 2004

The CsLnMSe3 semiconductors (Ln = rare-earth element, Y; M = Zn, Cd, Hg).

Inorg Chem 2003 Jun;42(13):4109-16

Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208-3113, USA.

CsLnCdSe(3) (Ln = Ce, Pr, Sm, Gd, Tb, Dy, Y) and CsLnHgSe(3) (Ln = La, Ce, Pr, Nd, Sm, Gd, Y) have been synthesized at 1123 K. These isostructural materials crystallize in the layered KZrCuS(3) structure type in the orthorhombic space group Cmcm and are group X extensions of the previously characterized Zn compounds. The structure is composed of two-dimensional [LnMSe(3)] layers that stack perpendicular to [010] and are separated by layers of face- and edge-sharing CsSe(8) bicapped trigonal prisms. Because there are no Se-Se bonds in the structure of CsLnMSe(3) (M = Zn, Cd, Hg), the formal oxidation states of Cs/Ln/M/Se are 1+/3+/2+/2-. CsSmHgSe(3) does not adhere to the Curie-Weiss law, whereas CsCeHgSe(3) and CsGdHgSe(3) are Curie-Weiss paramagnets with micro (eff) values of 2.77 and 7.90 micro (B), corresponding well with the theoretical values of 2.54 and 7.94 micro (B) for Ce(3+) and Gd(3+), respectively. Single-crystal optical absorption measurements were performed with polarized light perpendicular to the (010) and (001) crystal faces of these materials. The band gaps of the (010) crystal faces range from 1.94 eV (CsCeHgSe(3)) to 2.58 eV (CsYCdSe(3)) whereas those of the (001) crystal faces span the range 2.37 eV (CsSmHgSe(3)) to 2.54 eV (CsYCdSe(3) and CsYHgSe(3)). The largest band gap variation between crystal faces is 0.06 eV for CsYCdSe(3). Theoretical calculations for CsYMSe(3) indicate that these materials are direct band gap semiconductors whose colors and optical band gaps are dependent upon the orbitals of Y, M, and Se.
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http://dx.doi.org/10.1021/ic020733fDOI Listing
June 2003

Synthesis, structure, electrical properties, and band structure calculations of TiAsTe.

Inorg Chem 2003 May;42(10):3194-8

Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.

The new compound TiAsTe has been synthesized by the reaction of the elements in a LiCl/KCl flux at 923 K. The compound crystallizes with four formula units in space group Immm of the orthorhombic system in a cell at 153 K of a = 3.5730(8) A, b = 5.249(1) A, c = 12.794(3) A, V = 240.0(1) A(3). The structure, which is of the NbPS structure type, is a three-dimensional extended framework built from bicapped TiAs(4)Te(4) trigonal prisms. It may be considered to comprise infinity (2) [TiTe] slabs perpendicular to [001] that are interspersed with linear infinity (1)[As] chains running along [010]. The As-As distances alternate at 2.554(2) and 2.695(2) A. Electrical and thermopower measurements indicate that TiAsTe is an n-type metallic compound. Density functional theory calculations help rationalize the chemical bonding and physical properties.
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http://dx.doi.org/10.1021/ic020688bDOI Listing
May 2003

Syntheses, Structures, and Theoretical Study of LaCuSTe and SmCuSTe.

Inorg Chem 1999 Dec;38(26):5978-5983

Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208-3113.

Two mixed-chalcogen compounds LaCuSTe and SmCuSTe have been synthesized by the reactions of the elements at 1123 K. LaCuSTe crystallizes in a cell of dimensions a = 6.4955(8) Å, b = 7.7692(9) Å, c = 7.4665(9) Å, and beta = 95.045(2) degrees (T = 153 K) with four formula units in space group C(2)(h)()(5)-P2(1)/c of the monoclinic system. Its structure is closely related to that of LaCuS(2). SmCuSTe crystallizes as a new structure type in a cell of dimensions a = 7.5195(8) Å, b = 12.6370(14) Å, and c = 7.5287(8) Å (T = 153 K) with eight formula units in space group D(2)(h)()(15)-Pbca of the orthorhombic system. In LaCuSTe, the La atom is coordinated by a bicapped trigonal prism of four S atoms and four Te atoms; in SmCuSTe, the Sm atom is coordinated by a monocapped trigonal prism of four S atoms and three Te atoms. In both structures, the Cu atom is coordinated by a tetrahedron of one S atom and three Te atoms, These structures are built from (CuSTe)(n)() sheets that are separated by the rare-earth-metal atoms. In LaCuSTe, a sheet comprises edge-sharing dimers of CuSTe(3) tetrahedra (Cu(2)S(2)Te(4)) that share each of their Te atoms with four neighboring dimers to form a mixed octagonal/quadrilateral net. In SmCuSTe, a sheet comprises a single tetrahedral CuSTe(3) unit that shares each of its Te atoms with three neighboring tetrahedra to form a hexagonal net. The band structures of these two compounds indicate that they should be semiconductors. The calculations also show that the substitution of Te atoms for S atoms lowers the energy gap compared with those of unsubstituted systems.
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http://dx.doi.org/10.1021/ic990835eDOI Listing
December 1999

Oxide Addition to a Reactive Polysulfide Flux: Synthesis of K(4)Ba

Angew Chem Int Ed Engl 2001 Jul;40(13):2515-2516

Department of Chemistry Northwestern University 2145 Sheridan Road Evanston, IL 60208-3113 (USA).

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July 2001

Oxide Addition to a Reactive Polysulfide Flux: Synthesis of K Ba[Ti OS ] Containing Isolated [Ti OS (S ) ] Clusters.

Angew Chem Int Ed Engl 2001 Jul;40(13):2515-2516

Department of Chemistry Northwestern University 2145 Sheridan Road Evanston, IL 60208-3113 (USA) Fax: (+1) 847-491-2976.

The zero-dimensional cluster compound K Ba[Ti OS (S ) ] has been synthesized from a reactive flux similar to that of K S and Ti used in the synthesis of the one-dimensional compound K Ti S , but augmented by the deliberate introduction of TiO . The picture shows the structure of the [Ti OS (S ) ] ion.
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http://dx.doi.org/10.1002/1521-3773(20010702)40:13<2515::AID-ANIE2515>3.0.CO;2-0DOI Listing
July 2001
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