Fu-Dong Shi

Fu-Dong Shi

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Fu-Dong Shi

Publications by authors named "Fu-Dong Shi"

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DNA Vaccination with Heat Shock Protein 70 Protects (NZB x NZW)F Mice from Systemic Lupus Erythematosus.

Arthritis Rheumatol 2020 Jan 13. Epub 2020 Jan 13.

Department of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA.

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http://dx.doi.org/10.1002/art.41202DOI Listing
January 2020

Race/ethnicity influences outcomes in young adults with supratentorial intracerebral hemorrhage.

Neurology 2020 Jan 22. Epub 2020 Jan 22.

From the Division of Neurocritical Care and Emergency Neurology, Department of Neurology (L.C.M., G.J.F., A.L., K.N.S.), Yale School of Medicine, New Haven, CT; Department of Emergency Medicine (O.A.), Department of Radiology (A.V.), Gardner Neuroscience Institute (O.A., A.V.), Department of Neurology & Rehabilitation Medicine (D.W.), and Comprehensive Stroke Center (D.W.), University of Cincinnati, OH; Barrow Neurological Institute (F.-D.S.), Phoenix, AZ; Department of Neurology (S.J.K.), Baltimore Veterans Administration Medical Center, University of Maryland; Division of Public Health Sciences, Department of Biostatistical Sciences (C.L.), Wake Forest University School of Medicine, Winston-Salem, NC; and Center for Public Health Genomics (C.L.), University of Virginia, Charlottesville.

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http://dx.doi.org/10.1212/WNL.0000000000008930DOI Listing
January 2020

Global brain inflammation in stroke.

Lancet Neurol 2019 Nov 8;18(11):1058-1066. Epub 2019 Jul 8.

China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; Tianjin Medical University General Hospital, Tianjin, China. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(19)30078-XDOI Listing
November 2019

Temporal and Spatial Dynamics of Astroglial Reaction and Immune Response in Cuprizone-Induced Demyelination.

Neurotox Res 2019 Nov 13. Epub 2019 Nov 13.

Institute of Neurology, Huashan Hospital, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, 200025, China.

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http://dx.doi.org/10.1007/s12640-019-00129-4DOI Listing
November 2019

The selective sphingosine 1-phosphate receptor 1 modulator RP101075 improves microvascular circulation after cerebrovascular thrombosis.

FASEB J 2019 Oct 5;33(10):10935-10941. Epub 2019 Jul 5.

Department of Basic Medical Sciences, University of Arizona College of Medicine, Phoenix, Arizona, USA.

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http://dx.doi.org/10.1096/fj.201900282RDOI Listing
October 2019

Dl-3-n-butylphthalide Reduces Neurovascular Inflammation and Ischemic Brain Injury in Mice.

Aging Dis 2019 Oct 1;10(5):964-976. Epub 2019 Oct 1.

1Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin 300052, China.

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http://dx.doi.org/10.14336/AD.2019.0608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764730PMC
October 2019

Augmented Brain Infiltration and Activation of Leukocytes After Cerebral Ischemia in Type 2 Diabetic Mice.

Front Immunol 2019 11;10:2392. Epub 2019 Oct 11.

Neuroprotection Research Laboratory, Departments of Radiology and Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.

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http://dx.doi.org/10.3389/fimmu.2019.02392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797587PMC
October 2019

Colivelin Rescues Ischemic Neuron and Axons Involving JAK/STAT3 Signaling Pathway.

Neuroscience 2019 Sep 30;416:198-206. Epub 2019 Jul 30.

Shanxi Medical University, Taiyuan, China; China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China; Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China. Electronic address:

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http://dx.doi.org/10.1016/j.neuroscience.2019.07.020DOI Listing
September 2019

Peroneus Longus Tendon Autograft is a Safe and Effective Alternative for Anterior Cruciate Ligament Reconstruction.

J Knee Surg 2019 Aug 11;32(8):804-811. Epub 2018 Sep 11.

Department of Orthopaedics, Tangshan People's Hospital, Tangshan, China.

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http://dx.doi.org/10.1055/s-0038-1669951DOI Listing
August 2019

Increased serum IL-36β and IL-36γ levels in patients with neuromyelitis optica spectrum disorders: association with disease activity.

BMC Neurol 2019 Aug 5;19(1):185. Epub 2019 Aug 5.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, No 154 Anshan Road, Heping District, Tianjin, 300052, China.

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http://dx.doi.org/10.1186/s12883-019-1415-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681488PMC
August 2019

Dissemination of brain inflammation in traumatic brain injury.

Cell Mol Immunol 2019 Jun 7;16(6):523-530. Epub 2019 Mar 7.

Departments of Neurology and Neurosurgery, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China.

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http://dx.doi.org/10.1038/s41423-019-0213-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804599PMC
June 2019

Astrocytic Interleukin-15 Reduces Pathology of Neuromyelitis Optica in Mice.

Front Immunol 2018 19;9:523. Epub 2018 Mar 19.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.

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http://dx.doi.org/10.3389/fimmu.2018.00523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867910PMC
April 2019

Enhancing natural killer cells is beneficial in multiple sclerosis - No.

Mult Scler 2019 04 13;25(4):512-513. Epub 2018 Nov 13.

Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ, USA/Center for Neuroinflammation, Beijing Tiantan Hospital, Capital Medical University, Beijing, China/Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.

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http://dx.doi.org/10.1177/1352458518799591DOI Listing
April 2019

Study of the cytological features of bone marrow mesenchymal stem cells from patients with neuromyelitis optica.

Int J Mol Med 2019 Mar 9;43(3):1395-1405. Epub 2019 Jan 9.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin 300052, P.R. China.

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http://www.spandidos-publications.com/10.3892/ijmm.2019.4056
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http://dx.doi.org/10.3892/ijmm.2019.4056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365084PMC
March 2019

Altered neurovascular coupling in neuromyelitis optica.

Hum Brain Mapp 2019 02 13;40(3):976-986. Epub 2018 Oct 13.

Department of Radiology and Tianjin Key Laboratory of Functional Imaging, Tianjin, China.

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http://doi.wiley.com/10.1002/hbm.24426
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http://dx.doi.org/10.1002/hbm.24426DOI Listing
February 2019

Bidirectional degeneration in the visual pathway in neuromyelitis optica spectrum disorder (NMOSD).

Mult Scler 2018 10 21;24(12):1585-1593. Epub 2017 Aug 21.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China/Department of Neurology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ, USA.

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http://dx.doi.org/10.1177/1352458517727604DOI Listing
October 2018

Suramin is a novel competitive antagonist selective to α1β2γ2 GABA over ρ1 GABA receptors.

Neuropharmacology 2018 10 30;141:148-157. Epub 2018 Aug 30.

Division of Neurobiology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00283908183058
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http://dx.doi.org/10.1016/j.neuropharm.2018.08.036DOI Listing
October 2018

Neuromyelitis optica spectrum disorders with and without connective tissue disorders.

BMC Neurol 2018 Oct 24;18(1):177. Epub 2018 Oct 24.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, No 154 Anshan Road, Heping District, Tianjin, 300052, China.

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https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-
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http://dx.doi.org/10.1186/s12883-018-1182-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199722PMC
October 2018

Multimodal characterization of gray matter alterations in neuromyelitis optica.

Mult Scler 2018 09 25;24(10):1308-1316. Epub 2017 Jul 25.

Center for Cognition and Brain Disorders, Hangzhou Normal University, Hangzhou, P.R. China/Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments, Hangzhou, P.R. China.

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http://dx.doi.org/10.1177/1352458517721053DOI Listing
September 2018

Relapse of neuromyelitis optica associated with oral progestin.

J Neurol Neurosurg Psychiatry 2018 07 9;89(7):788-789. Epub 2017 Oct 9.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.

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http://dx.doi.org/10.1136/jnnp-2017-316356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031264PMC
July 2018

Depletion of microglia augments the dopaminergic neurotoxicity of MPTP.

FASEB J 2018 06 22;32(6):3336-3345. Epub 2018 Jan 22.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.

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http://www.fasebj.org/doi/10.1096/fj.201700833RR
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http://dx.doi.org/10.1096/fj.201700833RRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956250PMC
June 2018

Acute prevertebral abscess secondary to intradiscal oxygen-ozone chemonucleolysis for treatment of a cervical disc herniation.

J Int Med Res 2018 Jun 27;46(6):2461-2465. Epub 2018 Mar 27.

1 Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.

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http://dx.doi.org/10.1177/0300060518764186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023037PMC
June 2018

Brain Ischemia Induces Diversified Neuroantigen-Specific T-Cell Responses That Exacerbate Brain Injury.

Stroke 2018 06 25;49(6):1471-1478. Epub 2018 Apr 25.

From the Department of Neurology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ (W.-N.J., K.W., F.-D.S., Q.L.)

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http://dx.doi.org/10.1161/STROKEAHA.118.020203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976228PMC
June 2018

Engineered agrin attenuates the severity of experimental autoimmune myasthenia gravis.

Muscle Nerve 2018 05 8;57(5):814-820. Epub 2018 Jan 8.

Department of Neurology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, 85013, USA.

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http://dx.doi.org/10.1002/mus.26025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910282PMC
May 2018

Activation of JAK/STAT3 restores NK-cell function and improves immune defense after brain ischemia.

FASEB J 2018 05 8;32(5):2757-2767. Epub 2018 Jan 8.

Center for Neuroinflammation, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

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http://dx.doi.org/10.1096/fj.201700962RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901379PMC
May 2018

Vinpocetine Inhibits NF-κB-Dependent Inflammation in Acute Ischemic Stroke Patients.

Transl Stroke Res 2018 04 9;9(2):174-184. Epub 2017 Jul 9.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Anshan Road, Heping District, Tianjin, 300052, China.

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http://dx.doi.org/10.1007/s12975-017-0549-zDOI Listing
April 2018

Anti-Rituximab antibody in patients with NMOSDs treated with low dose Rituximab.

J Neuroimmunol 2018 03 28;316:107-111. Epub 2017 Dec 28.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin 300052, China. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2017.12.021DOI Listing
March 2018

Stroke-induced immunosuppression and poststroke infection.

Stroke Vasc Neurol 2018 Mar 12;3(1):34-41. Epub 2018 Jan 12.

Departments of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.

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http://dx.doi.org/10.1136/svn-2017-000123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870641PMC
March 2018

Different patterns of longitudinal brain and spinal cord changes and their associations with disability progression in NMO and MS.

Eur Radiol 2018 Jan 30;28(1):96-103. Epub 2017 Jun 30.

Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, People's Republic of China.

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http://dx.doi.org/10.1007/s00330-017-4921-xDOI Listing
January 2018

Organ- and cell-specific immune responses are associated with the outcomes of intracerebral hemorrhage.

FASEB J 2018 01 6;32(1):220-229. Epub 2017 Sep 6.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China;

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http://dx.doi.org/10.1096/fj.201700324RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731128PMC
January 2018

Bortezomib for Neuromyelitis Optica Spectrum Disorder: A New Therapeutic Option for the More Severe Forms?-Reply.

JAMA Neurol 2018 01;75(1):129-130

Departments of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.

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http://dx.doi.org/10.1001/jamaneurol.2017.3450DOI Listing
January 2018

Functional Improvement Among Intracerebral Hemorrhage (ICH) Survivors up to 12 Months Post-injury.

Neurocrit Care 2017 Dec;27(3):326-333

Division of Neurocritical Care and Emergency Neurology, Department of Neurology, Yale University School of Medicine, 15 York St, LCI 1003, New Haven, CT, 06510, USA.

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http://dx.doi.org/10.1007/s12028-017-0425-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700855PMC
December 2017

Infiltration and persistence of lymphocytes during late-stage cerebral ischemia in middle cerebral artery occlusion and photothrombotic stroke models.

J Neuroinflammation 2017 Dec 15;14(1):248. Epub 2017 Dec 15.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China.

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http://dx.doi.org/10.1186/s12974-017-1017-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732427PMC
December 2017

Low expression of complement inhibitory protein CD59 contributes to humoral autoimmunity against astrocytes.

Brain Behav Immun 2017 Oct 2;65:173-182. Epub 2017 May 2.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin 300052, China; Key Laboratory of the Ministry of Education for Medicinal Resources and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China, College of Life Sciences, Shaanxi Normal University, Xi'an 710000, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2017.04.023DOI Listing
October 2017

Rationale and design of combination of an immune modulator Fingolimod with Alteplase bridging with Mechanical Thrombectomy in Acute Ischemic Stroke (FAMTAIS) trial.

Int J Stroke 2017 10 1;12(8):906-909. Epub 2017 Jun 1.

1 Department of Neurology, the Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China.

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http://dx.doi.org/10.1177/1747493017710340DOI Listing
October 2017

A TSPO ligand attenuates brain injury after intracerebral hemorrhage.

FASEB J 2017 08 17;31(8):3278-3287. Epub 2017 Apr 17.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China;

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http://dx.doi.org/10.1096/fj.201601377RRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503714PMC
August 2017

Safety and Efficacy of Bortezomib in Patients With Highly Relapsing Neuromyelitis Optica Spectrum Disorder.

JAMA Neurol 2017 08;74(8):1010-1012

Tianjin Neurological Institute, Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China.

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http://dx.doi.org/10.1001/jamaneurol.2017.1336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822186PMC
August 2017

Colony stimulating factor 1 receptor inhibition eliminates microglia and attenuates brain injury after intracerebral hemorrhage.

J Cereb Blood Flow Metab 2017 Jul 1;37(7):2383-2395. Epub 2016 Jan 1.

1 Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.

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http://dx.doi.org/10.1177/0271678X16666551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482387PMC
July 2017

Acetylcholine-producing NK cells attenuate CNS inflammation via modulation of infiltrating monocytes/macrophages.

Proc Natl Acad Sci U S A 2017 07 10;114(30):E6202-E6211. Epub 2017 Jul 10.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin 300052, China;

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http://dx.doi.org/10.1073/pnas.1705491114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544318PMC
July 2017

Comparison of brain and spinal cord magnetic resonance imaging features in neuromyelitis optica spectrum disorders patients with or without aquaporin-4 antibody.

Mult Scler Relat Disord 2017 Apr 7;13:58-66. Epub 2017 Feb 7.

Department of Neurology, Key Laboratory of Posttraumatic Neuro-repair and Regeneration in the Central Nervous System, Tianjin Neurological Institute, Tianjin Medical University General Hospital, China; Barrow Neurological Institute, St Joseph's Hospital and Medical Center, USA.

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http://dx.doi.org/10.1016/j.msard.2017.02.003DOI Listing
April 2017

Brain Ischemia Suppresses Immunity in the Periphery and Brain via Different Neurogenic Innervations.

Immunity 2017 03 14;46(3):474-487. Epub 2017 Mar 14.

Departments of Neurology and Radiology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin 300052, China; Department of Neurology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ 85013, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.02.015DOI Listing
March 2017

Astrocyte-derived interleukin-15 exacerbates ischemic brain injury via propagation of cellular immunity.

Proc Natl Acad Sci U S A 2017 01 19;114(3):E396-E405. Epub 2016 Dec 19.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin 300052, China;

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http://dx.doi.org/10.1073/pnas.1612930114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5255606PMC
January 2017

Autoantibody to MOG suggests two distinct clinical subtypes of NMOSD.

Sci China Life Sci 2016 Dec 26;59(12):1270-1281. Epub 2016 Feb 26.

Departments of Neurology and Immunology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China.

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http://dx.doi.org/10.1007/s11427-015-4997-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101174PMC
December 2016

Intracerebral Hemorrhage Location and Functional Outcomes of Patients: A Systematic Literature Review and Meta-Analysis.

Neurocrit Care 2016 12;25(3):384-391

Division of Neurocritical Care and Emergency Neurology, Department of Neurology, Yale University School of Medicine, 15 York St, LCI 1003, New Haven, CT, 06510, USA.

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http://dx.doi.org/10.1007/s12028-016-0276-4DOI Listing
December 2016

Dimethyl Fumarate and Monomethyl Fumarate Promote Post-Ischemic Recovery in Mice.

Transl Stroke Res 2016 12 10;7(6):535-547. Epub 2016 Sep 10.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China.

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http://dx.doi.org/10.1007/s12975-016-0496-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065588PMC
December 2016

Thalamic Atrophy Contributes to Low Slow Wave Sleep in Neuromyelitis Optica Spectrum Disorder.

Aging Dis 2016 Dec 1;7(6):691-696. Epub 2016 Dec 1.

1Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin 300052, China.

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http://dx.doi.org/10.14336/AD.2016.0419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198860PMC
December 2016

CFHR1-Modified Neural Stem Cells Ameliorated Brain Injury in a Mouse Model of Neuromyelitis Optica Spectrum Disorders.

J Immunol 2016 11 26;197(9):3471-3480. Epub 2016 Sep 26.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin 300052, China;

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http://dx.doi.org/10.4049/jimmunol.1600135DOI Listing
November 2016

mTORC1 pathway disruption ameliorates brain inflammation following stroke via a shift in microglia phenotype from M1 type to M2 type.

FASEB J 2016 10 24;30(10):3388-3399. Epub 2016 Jun 24.

Department of Neurology and Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China;

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http://dx.doi.org/10.1096/fj.201600495RDOI Listing
October 2016

Augmentation of Circulating Follicular Helper T Cells and Their Impact on Autoreactive B Cells in Myasthenia Gravis.

J Immunol 2016 10 19;197(7):2610-7. Epub 2016 Aug 19.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin 300052, China; and

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http://dx.doi.org/10.4049/jimmunol.1500725DOI Listing
October 2016

Non-invasive tracking of CD4+ T cells with a paramagnetic and fluorescent nanoparticle in brain ischemia.

J Cereb Blood Flow Metab 2016 08 19;36(8):1464-76. Epub 2015 Oct 19.

Departments of Neurology, Immunology, Radiology, Key Laboratory of Neurorepair and Regeneration, Tianjin and Ministry of Education, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China Department of Neurology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ, USA.

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http://dx.doi.org/10.1177/0271678X15611137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971610PMC
August 2016

Impact of Autologous Mesenchymal Stem Cell Infusion on Neuromyelitis Optica Spectrum Disorder: A Pilot, 2-Year Observational Study.

CNS Neurosci Ther 2016 08 24;22(8):677-85. Epub 2016 May 24.

Departments of Neurology, Radiology, Ophthalmology, Hematology, Tianjin Medical University General Hospital, Tianjin Medical University Eye Hospital, Tianjin, China.

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http://doi.wiley.com/10.1111/cns.12559
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http://dx.doi.org/10.1111/cns.12559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492909PMC
August 2016

Sleep and Cognitive Abnormalities in Acute Minor Thalamic Infarction.

Neurosci Bull 2016 Aug 30;32(4):341-8. Epub 2016 May 30.

Department of Neurology, Tianjin Medical University General Hospital, Tianjin, 300052, China.

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http://dx.doi.org/10.1007/s12264-016-0036-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563779PMC
August 2016

Selective Sphingosine-1-Phosphate Receptor 1 Modulation Attenuates Experimental Intracerebral Hemorrhage.

Stroke 2016 07 12;47(7):1899-906. Epub 2016 May 12.

From the Departments of Neurology (N.S., Y.S., K.S., Y.F., J.H., Q.L., F.-D.S.) and Radiology (W.H.), Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China; Department of Neurology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ (N.S., K.W., Q.L., F.-D.S.); Department of Neurology, Yale University School of Medicine, New Haven, CT (K.N.S.); and Department of Clinical Research and Multiple Sclerosis Center, Neurology and Neuroscience Associates, Unity Health Network, Akron, OH (D.H.).

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http://stroke.ahajournals.org/content/47/7/1899.full.pdf
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http://dx.doi.org/10.1161/STROKEAHA.115.012236DOI Listing
July 2016

Increased resistin levels in the serum and cerebrospinal fluid of patients with neuromyelitis optica.

Clin Chim Acta 2016 May 19;456:176-179. Epub 2016 Mar 19.

Department of Neurology and Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China. Electronic address:

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http://dx.doi.org/10.1016/j.cca.2016.03.011DOI Listing
May 2016

Neural stem cells sustain natural killer cells that dictate recovery from brain inflammation.

Nat Neurosci 2016 Feb 11;19(2):243-52. Epub 2016 Jan 11.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.

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http://dx.doi.org/10.1038/nn.4211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336309PMC
February 2016

The Effect of Memantine on Cognitive Function and Behavioral and Psychological Symptoms in Mild-to-Moderate Alzheimer's Disease Patients.

Dement Geriatr Cogn Disord 2015 5;40(1-2):85-93. Epub 2015 Jun 5.

Department of Neurology, Key Laboratory of Post-Traumatic Neuro-Repair and Regeneration in the Central Nervous System, Ministry of Education, Tianjin Key Laboratory of Injuries, Variations and Regeneration of the Nervous System, and Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.

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http://dx.doi.org/10.1159/000430808DOI Listing
January 2016

NK cell phenotypic modulation in lung cancer environment.

PLoS One 2014 9;9(10):e109976. Epub 2014 Oct 9.

Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Micro-environment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, P.R. China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0109976PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192363PMC
December 2015

Fingolimod alters inflammatory mediators and vascular permeability in intracerebral hemorrhage.

Neurosci Bull 2015 Dec 10;31(6):755-62. Epub 2015 May 10.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China.

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http://dx.doi.org/10.1007/s12264-015-1532-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563722PMC
December 2015

Multimodal Quantitative MR Imaging of the Thalamus in Multiple Sclerosis and Neuromyelitis Optica.

Radiology 2015 Dec 4;277(3):784-92. Epub 2015 Jun 4.

From the Departments of Radiology (Y.L., Y.D., J.H., Z.R., K.L.) and Neurology (J.Y., H.D.), Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China; Department of Radiology and Nuclear Medicine, Neuroscience Campus Amsterdam (Y.L., F.B., H.V., M.P.W.), and Department of Physics and Medical Technology (H.V.), VU University Medical Center Amsterdam, Amsterdam, the Netherlands; Department of Neurology and Tianjin Neurologic Institute, Tianjin Medical University General Hospital, Tianjin, P. R. China (Y.L., F.D.S.); Center for Cognition and Brain Disorders, Hangzhou Normal University, Hangzhou 310015, P. R. China (J.W.); and Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments, Hangzhou, P. R. China (J.W.).

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http://dx.doi.org/10.1148/radiol.2015142786DOI Listing
December 2015

Neuroinflammation.

Authors:
Fu-Dong Shi

Neurosci Bull 2015 Dec;31(6):714-6

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China.

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http://dx.doi.org/10.1007/s12264-015-1568-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563734PMC
December 2015

Structural MRI substrates of cognitive impairment in neuromyelitis optica.

Neurology 2015 Oct 30;85(17):1491-9. Epub 2015 Sep 30.

From the Department of Neurology and Tianjin Neurological Institute (Y.L., Y.F., Nan Zhang, M.F., L.S., Y.S., Y.Y., L.Y., F.-D.S.) and Department of Radiology (Q.W., Ningnannan Zhang, C.Y.), Tianjin Medical University General Hospital, PR China; Department of Radiology and Nuclear Medicine, Neuroscience Campus Amsterdam (Y.L., M.M.S., F.B.), and Department of Anatomy and Neuroscience (M.M.S.), VU University Medical Center, Amsterdam, the Netherlands; and Department of Radiology (Y.L.), Xuanwu Hospital, Capital Medical University, Beijing, PR China.

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http://dx.doi.org/10.1212/WNL.0000000000002067DOI Listing
October 2015

Neurological picture. Multiple intracranial arteritis and hypothyroidism secondary to Streptococcus anginosus infection.

J Neurol Neurosurg Psychiatry 2015 Sep 20;86(9):1044-5. Epub 2014 Aug 20.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.

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http://jnnp.bmj.com/lookup/doi/10.1136/jnnp-2014-308048
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http://dx.doi.org/10.1136/jnnp-2014-308048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552935PMC
September 2015

Combination of the Immune Modulator Fingolimod With Alteplase in Acute Ischemic Stroke: A Pilot Trial.

Circulation 2015 Sep 22;132(12):1104-1112. Epub 2015 Jul 22.

Departments of Neurology, Immunology, Radiology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.016371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580515PMC
September 2015

Immune interventions in stroke.

Nat Rev Neurol 2015 Sep 25;11(9):524-35. Epub 2015 Aug 25.

Departments of Neurology and Immunology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin 300052, China.

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http://www.nature.com/articles/nrneurol.2015.144
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http://dx.doi.org/10.1038/nrneurol.2015.144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851339PMC
September 2015

Olfactory dysfunction in neuromyelitis optica spectrum disorders.

J Neurol 2015 Aug 28;262(8):1890-8. Epub 2015 May 28.

Department of Neurology, Tianjin Neurological Institute, Radiology, Tianjin Key Laboratory of Functional Imaging, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin, 300052, China.

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http://dx.doi.org/10.1007/s00415-015-7787-3DOI Listing
August 2015

Chromosome 9p21.3 Variants Are Associated with Cerebral Infarction in Chinese Population.

J Mol Neurosci 2015 Jul 11;56(3):546-52. Epub 2015 Feb 11.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China.

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http://dx.doi.org/10.1007/s12031-015-0494-9DOI Listing
July 2015

Hypoxemia, Sleep Disturbances, and Depression Correlated with Fatigue in Neuromyelitis Optica Spectrum Disorder.

CNS Neurosci Ther 2015 Jul 1;21(7):599-606. Epub 2015 Jun 1.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.

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http://dx.doi.org/10.1111/cns.12411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478121PMC
July 2015

Sleep abnormality in neuromyelitis optica spectrum disorder.

Neurol Neuroimmunol Neuroinflamm 2015 Jun 16;2(3):e94. Epub 2015 Apr 16.

Departments of Neurology (Y. Song, L.P., Y.F., N.S., Y.-J.L., H.C., L.S., Y. Shen, L.C., F.-D.S.) and Immunology (F.-D.S.), Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China; and Department of Neurology (F.D.-S.), Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ.

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http://dx.doi.org/10.1212/NXI.0000000000000094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405292PMC
June 2015

Altered thalamic functional connectivity in multiple sclerosis.

Eur J Radiol 2015 Apr 19;84(4):703-8. Epub 2015 Jan 19.

Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ejrad.2015.01.001DOI Listing
April 2015

Differential patterns of spinal cord and brain atrophy in NMO and MS.

Neurology 2015 Apr 11;84(14):1465-72. Epub 2015 Mar 11.

From the Departments of Radiology (Y.L., Y.D., J.H., Z.R., K.L.) and Neurology (J.Y., H.D.), Xuanwu Hospital, Capital Medical University, Beijing, China; the Department of Radiology and Nuclear Medicine, Neuroscience Campus Amsterdam (Y.L., M.D., H.V., M.P.W., F.B.), and the Department of Anatomy and Neurosciences, Section of Clinical Neuroscience (M.D.), VU University Medical Center, Amsterdam, the Netherlands; the Department of Neurology and Tianjin Neurological Institute (Y.L., F.-D.S.), Tianjin Medical University, General Hospital, China; the Center for Cognition and Brain Disorders (J.W.), Hangzhou Normal University; Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments (J.W.), Hangzhou, China; and Fraunhofer MEVIS (F.W., H.K.H.), Institute for Medical Image Computing, Bremen, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000001441DOI Listing
April 2015

Association of circulating follicular helper T cells with disease course of NMO spectrum disorders.

J Neuroimmunol 2015 Jan 14;278:239-46. Epub 2014 Nov 14.

Department of Neurology and Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin 300052, China. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2014.11.011DOI Listing
January 2015

Quantitative analysis of aquaporin-4 antibody in longitudinally extensive transverse myelitis.

J Neuroimmunol 2015 Jan 5;278:26-9. Epub 2014 Dec 5.

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2014.12.006DOI Listing
January 2015

Alterations of natural killer cells in traumatic brain injury.

Neurosci Bull 2014 Dec 2;30(6):903-912. Epub 2014 Dec 2.

Departments of Neurology and Neurosurgery, Key Laboratory of Post-trauma Neuro-repair and Regeneration in the Central Nervous System, Ministry of Education, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, 300052, China.

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http://dx.doi.org/10.1007/s12264-014-1481-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562566PMC
December 2014

Impact of an immune modulator fingolimod on acute ischemic stroke.

Proc Natl Acad Sci U S A 2014 Dec 8;111(51):18315-20. Epub 2014 Dec 8.

Departments of Neurology and Department of Neurology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ 85013; and Department of Immunology, Tianjin Medical University, Tianjin, 300070, China

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http://dx.doi.org/10.1073/pnas.1416166111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280578PMC
December 2014

Interleukin-17 inhibits adult hippocampal neurogenesis.

Sci Rep 2014 Dec 19;4:7554. Epub 2014 Dec 19.

1] Divisions of Neurology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ, USA [2] Department of Physiology, Shantou University of Medical College, Shantou, Guangdong, China.

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http://dx.doi.org/10.1038/srep07554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271266PMC
December 2014

Interleukin-7 expression and its effect on natural killer cells in patients with multiple sclerosis.

J Neuroimmunol 2014 Nov 27;276(1-2):180-6. Epub 2014 Aug 27.

Department of Neurology, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ 85013, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2014.08.618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254214PMC
November 2014

Cortical thinning correlates with cognitive change in multiple sclerosis but not in neuromyelitis optica.

Eur Radiol 2014 Sep 7;24(9):2334-43. Epub 2014 Jun 7.

Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, People's Republic of China.

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http://dx.doi.org/10.1007/s00330-014-3239-1DOI Listing
September 2014

Fingolimod for the treatment of intracerebral hemorrhage: a 2-arm proof-of-concept study.

JAMA Neurol 2014 Sep;71(9):1092-101

Department of Neurology, Key Laboratory of Neurorepair and Regeneration, Tianjin and Ministry of Education, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China4Department of Immunology, Tianjin Medical University, T.

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http://dx.doi.org/10.1001/jamaneurol.2014.1065DOI Listing
September 2014

IL-17 promotes murine lupus.

J Immunol 2014 Jul 11;193(2):540-3. Epub 2014 Jun 11.

Division of Rheumatology, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095; and

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http://dx.doi.org/10.4049/jimmunol.1400931DOI Listing
July 2014

Regulatory CD4+ T cells promote B cell anergy in murine lupus.

J Immunol 2014 May 26;192(9):4069-73. Epub 2014 Mar 26.

Division of Rheumatology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095;

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http://dx.doi.org/10.4049/jimmunol.1302897DOI Listing
May 2014

Structural damage and functional reorganization in ipsilesional m1 in well-recovered patients with subcortical stroke.

Stroke 2014 Mar 4;45(3):788-93. Epub 2014 Feb 4.

From the Department of Radiology, Tianjin Key Laboratory of Functional Imaging (J.Z., L.M., W.Q., N.L., C.Y.) and Department of Neurology, Tianjin Neurological Institute (F.-D.S.), Tianjin Medical University General Hospital, Tianjin, China.

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.113.003425
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http://dx.doi.org/10.1161/STROKEAHA.113.003425DOI Listing
March 2014

Glatiramer acetate ameliorates experimental autoimmune neuritis.

Immunol Cell Biol 2014 Feb 26;92(2):164-9. Epub 2013 Nov 26.

1] Department of Neurology and Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China [2] Department of Neurology, Barrow Neurological Institute, St Joseph's Hospital and Medical Center, Phoenix, AZ, USA.

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http://dx.doi.org/10.1038/icb.2013.81DOI Listing
February 2014

CX3CR1 deficiency suppresses activation and neurotoxicity of microglia/macrophage in experimental ischemic stroke.

J Neuroinflammation 2014 Feb 3;11:26. Epub 2014 Feb 3.

Department of Neurology and the BNI-ASU Center for Preclinical Imaging, Barrow Neurological Institute, St, Joseph's Hospital and Medical Center, 350 West Thomas Road, Phoenix, Arizona 85013, USA.

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http://dx.doi.org/10.1186/1742-2094-11-26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942808PMC
February 2014

Ischemic neurons recruit natural killer cells that accelerate brain infarction.

Proc Natl Acad Sci U S A 2014 Feb 3;111(7):2704-9. Epub 2014 Feb 3.

Department of Neurology, Key Laboratory of Neurorepair and Regeneration, Tianjin and Ministry of Education and Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin 300052, China.

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http://dx.doi.org/10.1073/pnas.1315943111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932858PMC
February 2014

Author response.

Neurology 2014 Feb;82(6):547

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February 2014

Leptin promotes lupus T-cell autoimmunity.

Clin Immunol 2013 Dec 12;149(3):530-3. Epub 2013 Sep 12.

Department of Medicine, University of California at Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.clim.2013.09.002DOI Listing
December 2013