Frits R Rosendaal

Frits R Rosendaal

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Frits R Rosendaal

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Associations of sleep duration and quality with serum and hepatic lipids: The Netherlands Epidemiology of Obesity Study.

J Sleep Res 2019 Aug 15;28(4):e12776. Epub 2018 Oct 15.

Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1111/jsr.12776DOI Listing
August 2019

Endogenous sex hormones and risk of venous thromboembolism in young women.

J Thromb Haemost 2019 Aug 4;17(8):1297-1304. Epub 2019 Jun 4.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1111/jth.14474DOI Listing
August 2019

Impact of prothrombotic genotypes on the association between family history of myocardial infarction and venous thromboembolism.

J Thromb Haemost 2019 Aug 7;17(8):1363-1371. Epub 2019 Jun 7.

K. G. Jebsen - Thrombosis Research and Expertise Center (TREC), Department of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway.

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http://dx.doi.org/10.1111/jth.14493DOI Listing
August 2019

Intrinsic Coagulation Pathway, History of Headache, and Risk of Ischemic Stroke.

Stroke 2019 Aug 9;50(8):2181-2186. Epub 2019 Jul 9.

Department of Epidemiology (F.R.R., B.S.S.), Leiden University Medical Center, the Netherlands.

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http://dx.doi.org/10.1161/STROKEAHA.118.023124DOI Listing
August 2019

Mendelian randomization analysis of cholesteryl ester transfer protein and subclinical atherosclerosis: A population-based study.

J Clin Lipidol 2018 Jan - Feb;12(1):137-144.e1. Epub 2017 Nov 2.

Department of Cardiology, Leiden University Medical Center (LUMC), Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.jacl.2017.10.023DOI Listing
July 2019

Associations of Outdoor Temperature, Bright Sunlight, and Cardiometabolic Traits in Two European Population-Based Cohorts.

J Clin Endocrinol Metab 2019 Jul;104(7):2903-2910

Radcliffe Department of Medicine, Oxford Centre for Diabetes, Endocrinology, and Metabolism, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1210/jc.2018-02532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543772PMC
July 2019

Hyperhomocysteinaemia and the risk of recurrent venous thrombosis: results from the MEGA follow-up study.

Br J Haematol 2019 Jul 1. Epub 2019 Jul 1.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1111/bjh.16075DOI Listing
July 2019

Glucose metabolism affects coagulation factors: The NEO study.

J Thromb Haemost 2019 Jul 20. Epub 2019 Jul 20.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1111/jth.14573DOI Listing
July 2019

Low Birth Weight and Kidney Function in Middle-Aged Men and Women: The Netherlands Epidemiology of Obesity Study.

Am J Kidney Dis 2019 Jul 26. Epub 2019 Jul 26.

Department of Nephrology, Leiden University Medical Center, Leiden, the Netherlands; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands; Department of Nephrology, Jeroen Bosch Hospital, Den Bosch, the Netherlands.

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http://dx.doi.org/10.1053/j.ajkd.2019.05.007DOI Listing
July 2019

Association of apolipoproteins C-I, C-II, C-III and E with coagulation markers and venous thromboembolism risk.

Clin Epidemiol 2019 22;11:625-633. Epub 2019 Jul 22.

Department of Clinical Chemistry and Laboratory Medicine, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.2147/CLEP.S196266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659780PMC
July 2019

Risk prediction of recurrent venous thrombosis; where are we now and what can we add?

J Thromb Haemost 2019 Jun 12. Epub 2019 Jun 12.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1111/jth.14535DOI Listing
June 2019

A limited number of medicines pragmatic trials had potential for waived informed consent following the 2016 CIOMS ethical guidelines.

J Clin Epidemiol 2019 Jun 15;114:60-71. Epub 2019 Jun 15.

Departments of Medicine, Health Research and Policy, Biomedical Data Science and Statistics, and Meta-Research Innovation Center at Stanford (METRICS), Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/j.jclinepi.2019.06.007DOI Listing
June 2019

Effect of prothrombotic genotypes on the risk of venous thromboembolism in patients with and without ischemic stroke. The Tromsø Study.

J Thromb Haemost 2019 May 12;17(5):749-758. Epub 2019 Mar 12.

K. G. Jebsen Thrombosis Research and Expertise Center (TREC), Department of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway.

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http://dx.doi.org/10.1111/jth.14410DOI Listing
May 2019

Post-thrombotic syndrome: Short and long-term incidence and risk factors.

Thromb Res 2019 May 6;177:102-109. Epub 2019 Mar 6.

Department of Thrombosis and Hemostasis, Leiden University Medical Center, Albinusdreef 2, 2300 RC Leiden, the Netherlands; Department of Clinical Epidemiology, Leiden University Medical Center, Albinusdreef 2, 2300 RC Leiden, the Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S00493848193015
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http://dx.doi.org/10.1016/j.thromres.2019.03.003DOI Listing
May 2019

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.

Authors:
Nicole M Warrington Robin N Beaumont Momoko Horikoshi Felix R Day Øyvind Helgeland Charles Laurin Jonas Bacelis Shouneng Peng Ke Hao Bjarke Feenstra Andrew R Wood Anubha Mahajan Jessica Tyrrell Neil R Robertson N William Rayner Zhen Qiao Gunn-Helen Moen Marc Vaudel Carmen J Marsit Jia Chen Michael Nodzenski Theresia M Schnurr Mohammad H Zafarmand Jonathan P Bradfield Niels Grarup Marjolein N Kooijman Ruifang Li-Gao Frank Geller Tarunveer S Ahluwalia Lavinia Paternoster Rico Rueedi Ville Huikari Jouke-Jan Hottenga Leo-Pekka Lyytikäinen Alana Cavadino Sarah Metrustry Diana L Cousminer Ying Wu Elisabeth Thiering Carol A Wang Christian T Have Natalia Vilor-Tejedor Peter K Joshi Jodie N Painter Ioanna Ntalla Ronny Myhre Niina Pitkänen Elisabeth M van Leeuwen Raimo Joro Vasiliki Lagou Rebecca C Richmond Ana Espinosa Sheila J Barton Hazel M Inskip John W Holloway Loreto Santa-Marina Xavier Estivill Wei Ang Julie A Marsh Christoph Reichetzeder Letizia Marullo Berthold Hocher Kathryn L Lunetta Joanne M Murabito Caroline L Relton Manolis Kogevinas Leda Chatzi Catherine Allard Luigi Bouchard Marie-France Hivert Ge Zhang Louis J Muglia Jani Heikkinen Camilla S Morgen Antoine H C van Kampen Barbera D C van Schaik Frank D Mentch Claudia Langenberg Jian'an Luan Robert A Scott Jing Hua Zhao Gibran Hemani Susan M Ring Amanda J Bennett Kyle J Gaulton Juan Fernandez-Tajes Natalie R van Zuydam Carolina Medina-Gomez Hugoline G de Haan Frits R Rosendaal Zoltán Kutalik Pedro Marques-Vidal Shikta Das Gonneke Willemsen Hamdi Mbarek Martina Müller-Nurasyid Marie Standl Emil V R Appel Cilius E Fonvig Caecilie Trier Catharina E M van Beijsterveldt Mario Murcia Mariona Bustamante Sílvia Bonas-Guarch David M Hougaard Josep M Mercader Allan Linneberg Katharina E Schraut Penelope A Lind Sarah E Medland Beverley M Shields Bridget A Knight Jin-Fang Chai Kalliope Panoutsopoulou Meike Bartels Friman Sánchez Jakob Stokholm David Torrents Rebecca K Vinding Sara M Willems Mustafa Atalay Bo L Chawes Peter Kovacs Inga Prokopenko Marcus A Tuke Hanieh Yaghootkar Katherine S Ruth Samuel E Jones Po-Ru Loh Anna Murray Michael N Weedon Anke Tönjes Michael Stumvoll Kim F Michaelsen Aino-Maija Eloranta Timo A Lakka Cornelia M van Duijn Wieland Kiess Antje Körner Harri Niinikoski Katja Pahkala Olli T Raitakari Bo Jacobsson Eleftheria Zeggini George V Dedoussis Yik-Ying Teo Seang-Mei Saw Grant W Montgomery Harry Campbell James F Wilson Tanja G M Vrijkotte Martine Vrijheid Eco J C N de Geus M Geoffrey Hayes Haja N Kadarmideen Jens-Christian Holm Lawrence J Beilin Craig E Pennell Joachim Heinrich Linda S Adair Judith B Borja Karen L Mohlke Johan G Eriksson Elisabeth E Widén Andrew T Hattersley Tim D Spector Mika Kähönen Jorma S Viikari Terho Lehtimäki Dorret I Boomsma Sylvain Sebert Peter Vollenweider Thorkild I A Sørensen Hans Bisgaard Klaus Bønnelykke Jeffrey C Murray Mads Melbye Ellen A Nohr Dennis O Mook-Kanamori Fernando Rivadeneira Albert Hofman Janine F Felix Vincent W V Jaddoe Torben Hansen Charlotta Pisinger Allan A Vaag Oluf Pedersen André G Uitterlinden Marjo-Riitta Järvelin Christine Power Elina Hyppönen Denise M Scholtens William L Lowe George Davey Smith Nicholas J Timpson Andrew P Morris Nicholas J Wareham Hakon Hakonarson Struan F A Grant Timothy M Frayling Debbie A Lawlor Pål R Njølstad Stefan Johansson Ken K Ong Mark I McCarthy John R B Perry David M Evans Rachel M Freathy

Nat Genet 2019 05 1;51(5):804-814. Epub 2019 May 1.

Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Royal Devon and Exeter Hospital, Exeter, UK.

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http://dx.doi.org/10.1038/s41588-019-0403-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522365PMC
May 2019

The Association between Habitual Sleep Duration and Sleep Quality with Glycemic Traits: Assessment by Cross-Sectional and Mendelian Randomization Analyses.

J Clin Med 2019 May 15;8(5). Epub 2019 May 15.

Department of Internal Medicine, section of Gerontology and Geriatrics, Leiden University Medical Center, P.O. Box 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.3390/jcm8050682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572144PMC
May 2019

The association of genetic variants in the cholesteryl ester transfer protein gene with hemostatic factors and a first venous thrombosis.

J Thromb Haemost 2019 May 31. Epub 2019 May 31.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1111/jth.14528DOI Listing
May 2019

Adult weight change in relation to visceral fat and liver fat at middle age: The Netherlands epidemiology of obesity study.

Int J Obes (Lond) 2019 Apr 19;43(4):790-799. Epub 2018 Jul 19.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/s41366-018-0163-5DOI Listing
April 2019

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.

Authors:
Amy R Bentley Yun J Sung Michael R Brown Thomas W Winkler Aldi T Kraja Ioanna Ntalla Karen Schwander Daniel I Chasman Elise Lim Xuan Deng Xiuqing Guo Jingmin Liu Yingchang Lu Ching-Yu Cheng Xueling Sim Dina Vojinovic Jennifer E Huffman Solomon K Musani Changwei Li Mary F Feitosa Melissa A Richard Raymond Noordam Jenna Baker Guanjie Chen Hugues Aschard Traci M Bartz Jingzhong Ding Rajkumar Dorajoo Alisa K Manning Tuomo Rankinen Albert V Smith Salman M Tajuddin Wei Zhao Mariaelisa Graff Maris Alver Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Evangelos Evangelou Chuan Gao Anuj Goel Yanick Hagemeijer Sarah E Harris Fernando P Hartwig Meian He Andrea R V R Horimoto Fang-Chi Hsu Yi-Jen Hung Anne U Jackson Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Karin Leander Keng-Hung Lin Jian'an Luan Leo-Pekka Lyytikäinen Nana Matoba Ilja M Nolte Maik Pietzner Bram Prins Muhammad Riaz Antonietta Robino M Abdullah Said Nicole Schupf Robert A Scott Tamar Sofer Alena Stancáková Fumihiko Takeuchi Bamidele O Tayo Peter J van der Most Tibor V Varga Tzung-Dau Wang Yajuan Wang Erin B Ware Wanqing Wen Yong-Bing Xiang Lisa R Yanek Weihua Zhang Jing Hua Zhao Adebowale Adeyemo Saima Afaq Najaf Amin Marzyeh Amini Dan E Arking Zorayr Arzumanyan Tin Aung Christie Ballantyne R Graham Barr Lawrence F Bielak Eric Boerwinkle Erwin P Bottinger Ulrich Broeckel Morris Brown Brian E Cade Archie Campbell Mickaël Canouil Sabanayagam Charumathi Yii-Der Ida Chen Kaare Christensen Maria Pina Concas John M Connell Lisa de Las Fuentes H Janaka de Silva Paul S de Vries Ayo Doumatey Qing Duan Charles B Eaton Ruben N Eppinga Jessica D Faul James S Floyd Nita G Forouhi Terrence Forrester Yechiel Friedlander Ilaria Gandin He Gao Mohsen Ghanbari Sina A Gharib Bruna Gigante Franco Giulianini Hans J Grabe C Charles Gu Tamara B Harris Sami Heikkinen Chew-Kiat Heng Makoto Hirata James E Hixson M Arfan Ikram Yucheng Jia Roby Joehanes Craig Johnson Jost Bruno Jonas Anne E Justice Tomohiro Katsuya Chiea Chuen Khor Tuomas O Kilpeläinen Woon-Puay Koh Ivana Kolcic Charles Kooperberg Jose E Krieger Stephen B Kritchevsky Michiaki Kubo Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Cora E Lewis Yize Li Jingjing Liang Shiow Lin Ching-Ti Liu Jianjun Liu Kiang Liu Marie Loh Kurt K Lohman Tin Louie Anna Luzzi Reedik Mägi Anubha Mahajan Ani W Manichaikul Colin A McKenzie Thomas Meitinger Andres Metspalu Yuri Milaneschi Lili Milani Karen L Mohlke Yukihide Momozawa Andrew P Morris Alison D Murray Mike A Nalls Matthias Nauck Christopher P Nelson Kari E North Jeffrey R O'Connell Nicholette D Palmer George J Papanicolau Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek Neil Poulter Olli T Raitakari Alex P Reiner Frida Renström Treva K Rice Stephen S Rich Jennifer G Robinson Lynda M Rose Frits R Rosendaal Igor Rudan Carsten O Schmidt Pamela J Schreiner William R Scott Peter Sever Yuan Shi Stephen Sidney Mario Sims Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Heather M Stringham Nicholas Y Q Tan Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham Henning Tiemeier Stephen T Turner André G Uitterlinden Diana van Heemst Melanie Waldenberger Heming Wang Lan Wang Lihua Wang Wen Bin Wei Christine A Williams Gregory Wilson Mary K Wojczynski Jie Yao Kristin Young Caizheng Yu Jian-Min Yuan Jie Zhou Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Richard S Cooper Ulf de Faire Ian J Deary Paul Elliott Tõnu Esko Martin Farrall Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Bernardo L Horta Jyh-Ming Jimmy Juang Yoichiro Kamatani Candace M Kammerer Norihiro Kato Jaspal S Kooner Markku Laakso Cathy C Laurie I-Te Lee Terho Lehtimäki Patrik K E Magnusson Albertine J Oldehinkel Brenda W J H Penninx Alexandre C Pereira Rainer Rauramaa Susan Redline Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Jun-Sing Wang Ya Xing Wang Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Tangchun Wu Eleftheria Zeggini Wei Zheng Claude Bouchard Michele K Evans Vilmundur Gudnason Sharon L R Kardia Yongmei Liu Bruce M Psaty Paul M Ridker Rob M van Dam Dennis O Mook-Kanamori Myriam Fornage Michael A Province Tanika N Kelly Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Ruth J F Loos Nora Franceschini Jerome I Rotter Xiaofeng Zhu Laura J Bierut W James Gauderman Kenneth Rice Patricia B Munroe Alanna C Morrison Dabeeru C Rao Charles N Rotimi L Adrienne Cupples

Nat Genet 2019 04 29;51(4):636-648. Epub 2019 Mar 29.

Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41588-019-0378-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467258PMC
April 2019

Repeat length variations in polyglutamine disease-associated genes affect body mass index.

Int J Obes (Lond) 2019 03 17;43(3):440-449. Epub 2018 Aug 17.

Department of Neurology, Leiden University Medical Centre, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/s41366-018-0161-7DOI Listing
March 2019

Glucose levels and diabetes are not associated with the risk of venous thrombosis: results from the MEGA case-control study.

Br J Haematol 2019 Feb 27;184(3):431-435. Epub 2018 Nov 27.

Department of Clinical Epidemiology, Leiden University Medical Centre, Leiden, the Netherlands.

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http://dx.doi.org/10.1111/bjh.15599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587875PMC
February 2019

Maintaining Research and Publication Integrity.

Clin Chem 2019 Feb 17;65(2):230-235. Epub 2018 Dec 17.

Professor of Clinical Epidemiology, Leiden University Medical Center, the Netherlands and representative of the UK Committee on Publication Ethics (COPE).

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http://www.clinchem.org/lookup/doi/10.1373/clinchem.2018.298
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http://dx.doi.org/10.1373/clinchem.2018.298901DOI Listing
February 2019

Further comments on "High-titre inhibitors in previously untreated patients with severe haemophilia A receiving recombinant or plasma-derived factor VIII: a budget-impact analysis".

Blood Transfus 2019 01 22;17(1):86. Epub 2017 Dec 22.

"A. Bianchi Bonomi" Haemophilia and Thrombosis Centre, "Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico" and Luigi Villa" Foundation, Milan, Italy.

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http://www.bloodtransfusion.it/articolosing.aspx?id=000950
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http://dx.doi.org/10.2450/2017.0253-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343594PMC
January 2019

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

Authors:
Mary F Feitosa Aldi T Kraja Daniel I Chasman Yun J Sung Thomas W Winkler Ioanna Ntalla Xiuqing Guo Nora Franceschini Ching-Yu Cheng Xueling Sim Dina Vojinovic Jonathan Marten Solomon K Musani Changwei Li Amy R Bentley Michael R Brown Karen Schwander Melissa A Richard Raymond Noordam Hugues Aschard Traci M Bartz Lawrence F Bielak Rajkumar Dorajoo Virginia Fisher Fernando P Hartwig Andrea R V R Horimoto Kurt K Lohman Alisa K Manning Tuomo Rankinen Albert V Smith Salman M Tajuddin Mary K Wojczynski Maris Alver Mathilde Boissel Qiuyin Cai Archie Campbell Jin Fang Chai Xu Chen Jasmin Divers Chuan Gao Anuj Goel Yanick Hagemeijer Sarah E Harris Meian He Fang-Chi Hsu Anne U Jackson Mika Kähönen Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Federica Laguzzi Jian'an Luan Nana Matoba Ilja M Nolte Sandosh Padmanabhan Muhammad Riaz Rico Rueedi Antonietta Robino M Abdullah Said Robert A Scott Tamar Sofer Alena Stančáková Fumihiko Takeuchi Bamidele O Tayo Peter J van der Most Tibor V Varga Veronique Vitart Yajuan Wang Erin B Ware Helen R Warren Stefan Weiss Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Najaf Amin Marzyeh Amini Dan E Arking Tin Aung Eric Boerwinkle Ingrid Borecki Ulrich Broeckel Morris Brown Marco Brumat Gregory L Burke Mickaël Canouil Aravinda Chakravarti Sabanayagam Charumathi Yii-Der Ida Chen John M Connell Adolfo Correa Lisa de Las Fuentes Renée de Mutsert H Janaka de Silva Xuan Deng Jingzhong Ding Qing Duan Charles B Eaton Georg Ehret Ruben N Eppinga Evangelos Evangelou Jessica D Faul Stephan B Felix Nita G Forouhi Terrence Forrester Oscar H Franco Yechiel Friedlander Ilaria Gandin He Gao Mohsen Ghanbari Bruna Gigante C Charles Gu Dongfeng Gu Saskia P Hagenaars Göran Hallmans Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Makoto Hirata Barbara V Howard M Arfan Ikram Ulrich John Tomohiro Katsuya Chiea Chuen Khor Tuomas O Kilpeläinen Woon-Puay Koh José E Krieger Stephen B Kritchevsky Michiaki Kubo Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Cora E Lewis Yize Li Shiow Lin Jianjun Liu Jingmin Liu Marie Loh Tin Louie Reedik Mägi Colin A McKenzie Thomas Meitinger Andres Metspalu Yuri Milaneschi Lili Milani Karen L Mohlke Yukihide Momozawa Mike A Nalls Christopher P Nelson Nona Sotoodehnia Jill M Norris Jeff R O'Connell Nicholette D Palmer Thomas Perls Nancy L Pedersen Annette Peters Patricia A Peyser Neil Poulter Leslie J Raffel Olli T Raitakari Kathryn Roll Lynda M Rose Frits R Rosendaal Jerome I Rotter Carsten O Schmidt Pamela J Schreiner Nicole Schupf William R Scott Peter S Sever Yuan Shi Stephen Sidney Mario Sims Colleen M Sitlani Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Heather M Stringham Nicholas Y Q Tan Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham Stephen T Turner André G Uitterlinden Peter Vollenweider Melanie Waldenberger Lihua Wang Ya Xing Wang Wen Bin Wei Christine Williams Jie Yao Caizheng Yu Jian-Min Yuan Wei Zhao Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Ian J Deary Tõnu Esko Martin Farrall Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Jost Bruno Jonas Yoichiro Kamatani Norihiro Kato Jaspal S Kooner Zoltán Kutalik Markku Laakso Cathy C Laurie Karin Leander Terho Lehtimäki Lifelines Cohort Study Patrik K E Magnusson Albertine J Oldehinkel Brenda W J H Penninx Ozren Polasek David J Porteous Rainer Rauramaa Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Tangchun Wu Wei Zheng Claude Bouchard Kaare Christensen Michele K Evans Vilmundur Gudnason Bernardo L Horta Sharon L R Kardia Yongmei Liu Alexandre C Pereira Bruce M Psaty Paul M Ridker Rob M van Dam W James Gauderman Xiaofeng Zhu Dennis O Mook-Kanamori Myriam Fornage Charles N Rotimi L Adrienne Cupples Tanika N Kelly Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Charles Kooperberg Walter Palmas Kenneth Rice Alanna C Morrison Paul Elliott Mark J Caulfield Patricia B Munroe Dabeeru C Rao Michael A Province Daniel Levy

PLoS One 2018 18;13(6):e0198166. Epub 2018 Jun 18.

The Framingham Heart Study, Framingham, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198166PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005576PMC
January 2019

Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.

Circulation 2019 Jan;139(5):620-635

Department of Epidemiology, (A.P.R., B.M.P., N.L.S.), University of Washington, Seattle.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.034532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438386PMC
January 2019

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.

Authors:
Aldi T Kraja Chunyu Liu Jessica L Fetterman Mariaelisa Graff Christian Theil Have Charles Gu Lisa R Yanek Mary F Feitosa Dan E Arking Daniel I Chasman Kristin Young Symen Ligthart W David Hill Stefan Weiss Jian'an Luan Franco Giulianini Ruifang Li-Gao Fernando P Hartwig Shiow J Lin Lihua Wang Tom G Richardson Jie Yao Eliana P Fernandez Mohsen Ghanbari Mary K Wojczynski Wen-Jane Lee Maria Argos Sebastian M Armasu Ruteja A Barve Kathleen A Ryan Ping An Thomas J Baranski Suzette J Bielinski Donald W Bowden Ulrich Broeckel Kaare Christensen Audrey Y Chu Janie Corley Simon R Cox Andre G Uitterlinden Fernando Rivadeneira Cheryl D Cropp E Warwick Daw Diana van Heemst Lisa de Las Fuentes He Gao Ioanna Tzoulaki Tarunveer S Ahluwalia Renée de Mutsert Leslie S Emery A Mesut Erzurumluoglu James A Perry Mao Fu Nita G Forouhi Zhenglong Gu Yang Hai Sarah E Harris Gibran Hemani Steven C Hunt Marguerite R Irvin Anna E Jonsson Anne E Justice Nicola D Kerrison Nicholas B Larson Keng-Hung Lin Latisha D Love-Gregory Rasika A Mathias Joseph H Lee Matthias Nauck Raymond Noordam Ken K Ong James Pankow Amit Patki Alison Pattie Astrid Petersmann Qibin Qi Rasmus Ribel-Madsen Rebecca Rohde Kevin Sandow Theresia M Schnurr Tamar Sofer John M Starr Adele M Taylor Alexander Teumer Nicholas J Timpson Hugoline G de Haan Yujie Wang Peter E Weeke Christine Williams Hongsheng Wu Wei Yang Donglin Zeng Daniel R Witte Bruce S Weir Nicholas J Wareham Henrik Vestergaard Stephen T Turner Christian Torp-Pedersen Evie Stergiakouli Wayne Huey-Herng Sheu Frits R Rosendaal M Arfan Ikram Oscar H Franco Paul M Ridker Thomas T Perls Oluf Pedersen Ellen A Nohr Anne B Newman Allan Linneberg Claudia Langenberg Tuomas O Kilpeläinen Sharon L R Kardia Marit E Jørgensen Torben Jørgensen Thorkild I A Sørensen Georg Homuth Torben Hansen Mark O Goodarzi Ian J Deary Cramer Christensen Yii-Der Ida Chen Aravinda Chakravarti Ivan Brandslund Klaus Bonnelykke Kent D Taylor James G Wilson Santiago Rodriguez Gail Davies Bernardo L Horta Bharat Thyagarajan D C Rao Niels Grarup Victor G Davila-Roman Gavin Hudson Xiuqing Guo Donna K Arnett Caroline Hayward Dhananjay Vaidya Dennis O Mook-Kanamori Hemant K Tiwari Daniel Levy Ruth J F Loos Abbas Dehghan Paul Elliott Afshan N Malik Robert A Scott Diane M Becker Mariza de Andrade Michael A Province James B Meigs Jerome I Rotter Kari E North

Am J Hum Genet 2019 Jan 27;104(1):112-138. Epub 2018 Dec 27.

Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27516, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323610PMC
January 2019

Illness perceptions and their association with 2 year functional status and change in patients with hand osteoarthritis.

Rheumatology (Oxford) 2018 12;57(12):2190-2199

Department of Rheumatology, Leiden University Medical Center, The Netherlands.

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http://dx.doi.org/10.1093/rheumatology/key231DOI Listing
December 2018

Direct oral anticoagulant use and subsequent start of proton pump inhibitors as proxy for gastric complaints.

Pharmacoepidemiol Drug Saf 2018 12 15;27(12):1371-1378. Epub 2018 Nov 15.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://doi.wiley.com/10.1002/pds.4684
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http://dx.doi.org/10.1002/pds.4684DOI Listing
December 2018

Associations of different body fat deposits with serum 25-hydroxyvitamin D concentrations.

Clin Nutr 2018 Dec 18. Epub 2018 Dec 18.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1016/j.clnu.2018.12.018DOI Listing
December 2018

Role of Routine Laboratory Tests in Assessing Risk of Recurrent Venous Thrombosis: Results from the MEGA Follow-Up Study.

Thromb Haemost 2018 Nov 24;118(11):1918-1929. Epub 2018 Oct 24.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1673694
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http://dx.doi.org/10.1055/s-0038-1673694DOI Listing
November 2018

Venous Thrombosis Risk after Arthroscopy of the Knee: Derivation and Validation of the L-TRiP(ascopy) Score.

Thromb Haemost 2018 Oct 20;118(10):1823-1831. Epub 2018 Sep 20.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1055/s-0038-1670660DOI Listing
October 2018

Habitual Sleep Measures are Associated with Overall Body Fat, and not Specifically with Visceral Fat, in Men and Women.

Obesity (Silver Spring) 2018 10;26(10):1651-1658

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.

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http://doi.wiley.com/10.1002/oby.22289
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October 2018

Next-generation DNA sequencing to identify novel genetic risk factors for cerebral vein thrombosis.

Thromb Res 2018 09 15;169:76-81. Epub 2018 Jun 15.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy; Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico and Fondazione Luigi Villa, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2018.06.011DOI Listing
September 2018

Sex differences in body fat distribution are related to sex differences in serum leptin and adiponectin.

Peptides 2018 09 1;107:25-31. Epub 2018 Aug 1.

Department of Clinical Epidemiology, Leiden University Medical Center (LUMC), PO-Box 9600, 2300RC, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.peptides.2018.07.008DOI Listing
September 2018

Hyperhomocysteinemia and Risk of First Venous Thrombosis: The Influence of (Unmeasured) Confounding Factors.

Am J Epidemiol 2018 07;187(7):1392-1400

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1093/aje/kwy004DOI Listing
July 2018

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.

Authors:
Annah B Wyss Tamar Sofer Mi Kyeong Lee Natalie Terzikhan Jennifer N Nguyen Lies Lahousse Jeanne C Latourelle Albert Vernon Smith Traci M Bartz Mary F Feitosa Wei Gao Tarunveer S Ahluwalia Wenbo Tang Christopher Oldmeadow Qing Duan Kim de Jong Mary K Wojczynski Xin-Qun Wang Raymond Noordam Fernando Pires Hartwig Victoria E Jackson Tianyuan Wang Ma'en Obeidat Brian D Hobbs Tianxiao Huan Hongsheng Gui Margaret M Parker Donglei Hu Lauren S Mogil Gleb Kichaev Jianping Jin Mariaelisa Graff Tamara B Harris Ravi Kalhan Susan R Heckbert Lavinia Paternoster Kristin M Burkart Yongmei Liu Elizabeth G Holliday James G Wilson Judith M Vonk Jason L Sanders R Graham Barr Renée de Mutsert Ana Maria Baptista Menezes Hieab H H Adams Maarten van den Berge Roby Joehanes Albert M Levin Jennifer Liberto Lenore J Launer Alanna C Morrison Colleen M Sitlani Juan C Celedón Stephen B Kritchevsky Rodney J Scott Kaare Christensen Jerome I Rotter Tobias N Bonten Fernando César Wehrmeister Yohan Bossé Shujie Xiao Sam Oh Nora Franceschini Jennifer A Brody Robert C Kaplan Kurt Lohman Mark McEvoy Michael A Province Frits R Rosendaal Kent D Taylor David C Nickle L Keoki Williams Esteban G Burchard Heather E Wheeler Don D Sin Vilmundur Gudnason Kari E North Myriam Fornage Bruce M Psaty Richard H Myers George O'Connor Torben Hansen Cathy C Laurie Patricia A Cassano Joohon Sung Woo Jin Kim John R Attia Leslie Lange H Marike Boezen Bharat Thyagarajan Stephen S Rich Dennis O Mook-Kanamori Bernardo Lessa Horta André G Uitterlinden Hae Kyung Im Michael H Cho Guy G Brusselle Sina A Gharib Josée Dupuis Ani Manichaikul Stephanie J London

Nat Commun 2018 07 30;9(1):2976. Epub 2018 Jul 30.

Epidemiology Branch National Institute of Environmental Health Sciences, National Institutes of Health, US Department of Health and Human Services, Research Triangle Park, NC, 27709, USA.

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http://dx.doi.org/10.1038/s41467-018-05369-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065313PMC
July 2018

Rosuvastatin use improves measures of coagulation in patients with venous thrombosis.

Eur Heart J 2018 May;39(19):1740-1747

Department of Clinical Epidemiology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1093/eurheartj/ehy014DOI Listing
May 2018

Associations between normal range albuminuria, renal function and cardiovascular function in a population-based imaging study.

Atherosclerosis 2018 05 16;272:94-100. Epub 2018 Mar 16.

Leiden University Medical Center, Dept. of Internal Medicine, Div. of Nephrology and Transplant Medicine Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.03.029DOI Listing
May 2018

Genetics of fasting and postprandial metabolite levels are overlapping.

Physiol Genomics 2018 04 26;50(4):235-236. Epub 2018 Jan 26.

Department of Clinical Epidemiology; Leiden University Medical Center , Leiden , the Netherlands.

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http://dx.doi.org/10.1152/physiolgenomics.00101.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966804PMC
April 2018

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.

Authors:
Anubha Mahajan Jennifer Wessel Sara M Willems Wei Zhao Neil R Robertson Audrey Y Chu Wei Gan Hidetoshi Kitajima Daniel Taliun N William Rayner Xiuqing Guo Yingchang Lu Man Li Richard A Jensen Yao Hu Shaofeng Huo Kurt K Lohman Weihua Zhang James P Cook Bram Peter Prins Jason Flannick Niels Grarup Vassily Vladimirovich Trubetskoy Jasmina Kravic Young Jin Kim Denis V Rybin Hanieh Yaghootkar Martina Müller-Nurasyid Karina Meidtner Ruifang Li-Gao Tibor V Varga Jonathan Marten Jin Li Albert Vernon Smith Ping An Symen Ligthart Stefan Gustafsson Giovanni Malerba Ayse Demirkan Juan Fernandez Tajes Valgerdur Steinthorsdottir Matthias Wuttke Cécile Lecoeur Michael Preuss Lawrence F Bielak Marielisa Graff Heather M Highland Anne E Justice Dajiang J Liu Eirini Marouli Gina Marie Peloso Helen R Warren Saima Afaq Shoaib Afzal Emma Ahlqvist Peter Almgren Najaf Amin Lia B Bang Alain G Bertoni Cristina Bombieri Jette Bork-Jensen Ivan Brandslund Jennifer A Brody Noël P Burtt Mickaël Canouil Yii-Der Ida Chen Yoon Shin Cho Cramer Christensen Sophie V Eastwood Kai-Uwe Eckardt Krista Fischer Giovanni Gambaro Vilmantas Giedraitis Megan L Grove Hugoline G de Haan Sophie Hackinger Yang Hai Sohee Han Anne Tybjærg-Hansen Marie-France Hivert Bo Isomaa Susanne Jäger Marit E Jørgensen Torben Jørgensen Annemari Käräjämäki Bong-Jo Kim Sung Soo Kim Heikki A Koistinen Peter Kovacs Jennifer Kriebel Florian Kronenberg Kristi Läll Leslie A Lange Jung-Jin Lee Benjamin Lehne Huaixing Li Keng-Hung Lin Allan Linneberg Ching-Ti Liu Jun Liu Marie Loh Reedik Mägi Vasiliki Mamakou Roberta McKean-Cowdin Girish Nadkarni Matt Neville Sune F Nielsen Ioanna Ntalla Patricia A Peyser Wolfgang Rathmann Kenneth Rice Stephen S Rich Line Rode Olov Rolandsson Sebastian Schönherr Elizabeth Selvin Kerrin S Small Alena Stančáková Praveen Surendran Kent D Taylor Tanya M Teslovich Barbara Thorand Gudmar Thorleifsson Adrienne Tin Anke Tönjes Anette Varbo Daniel R Witte Andrew R Wood Pranav Yajnik Jie Yao Loïc Yengo Robin Young Philippe Amouyel Heiner Boeing Eric Boerwinkle Erwin P Bottinger Rajiv Chowdhury Francis S Collins George Dedoussis Abbas Dehghan Panos Deloukas Marco M Ferrario Jean Ferrières Jose C Florez Philippe Frossard Vilmundur Gudnason Tamara B Harris Susan R Heckbert Joanna M M Howson Martin Ingelsson Sekar Kathiresan Frank Kee Johanna Kuusisto Claudia Langenberg Lenore J Launer Cecilia M Lindgren Satu Männistö Thomas Meitinger Olle Melander Karen L Mohlke Marie Moitry Andrew D Morris Alison D Murray Renée de Mutsert Marju Orho-Melander Katharine R Owen Markus Perola Annette Peters Michael A Province Asif Rasheed Paul M Ridker Fernando Rivadineira Frits R Rosendaal Anders H Rosengren Veikko Salomaa Wayne H-H Sheu Rob Sladek Blair H Smith Konstantin Strauch André G Uitterlinden Rohit Varma Cristen J Willer Matthias Blüher Adam S Butterworth John Campbell Chambers Daniel I Chasman John Danesh Cornelia van Duijn Josée Dupuis Oscar H Franco Paul W Franks Philippe Froguel Harald Grallert Leif Groop Bok-Ghee Han Torben Hansen Andrew T Hattersley Caroline Hayward Erik Ingelsson Sharon L R Kardia Fredrik Karpe Jaspal Singh Kooner Anna Köttgen Kari Kuulasmaa Markku Laakso Xu Lin Lars Lind Yongmei Liu Ruth J F Loos Jonathan Marchini Andres Metspalu Dennis Mook-Kanamori Børge G Nordestgaard Colin N A Palmer James S Pankow Oluf Pedersen Bruce M Psaty Rainer Rauramaa Naveed Sattar Matthias B Schulze Nicole Soranzo Timothy D Spector Kari Stefansson Michael Stumvoll Unnur Thorsteinsdottir Tiinamaija Tuomi Jaakko Tuomilehto Nicholas J Wareham James G Wilson Eleftheria Zeggini Robert A Scott Inês Barroso Timothy M Frayling Mark O Goodarzi James B Meigs Michael Boehnke Danish Saleheen Andrew P Morris Jerome I Rotter Mark I McCarthy

Nat Genet 2018 04 9;50(4):559-571. Epub 2018 Apr 9.

Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/s41588-018-0084-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898373PMC
April 2018

Biomarkers, menopausal hormone therapy and risk of venous thrombosis: The Women's Health Initiative.

Res Pract Thromb Haemost 2018 Apr 17;2(2):310-319. Epub 2018 Apr 17.

Program on Prevention Outcomes and Practices Stanford Prevention Research Center Stanford University Palo Alto CA USA.

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http://dx.doi.org/10.1002/rth2.12100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974918PMC
April 2018

Factor V levels and risk of venous thrombosis: The MEGA case-control study.

Res Pract Thromb Haemost 2018 Apr 14;2(2):320-326. Epub 2018 Apr 14.

Department of Thrombosis and Haemostasis Leiden University Medical Center Leiden The Netherlands.

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http://doi.wiley.com/10.1002/rth2.12091
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http://dx.doi.org/10.1002/rth2.12091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055494PMC
April 2018

Relation of Overall and Abdominal Adiposity With Electrocardiogram Parameters of Subclinical Cardiovascular Disease in Individuals Aged 45 to 65 Years (from the Netherlands Epidemiology of Obesity Study).

Am J Cardiol 2018 03 11;121(5):570-578. Epub 2017 Dec 11.

Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S00029149173185
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http://dx.doi.org/10.1016/j.amjcard.2017.11.030DOI Listing
March 2018

High-titre inhibitors in previously untreated patients with severe haemophilia A receiving recombinant or plasma-derived factor VIII: a budget-impact analysis.

Blood Transfus 2018 02 15;16(2):215-220. Epub 2017 May 15.

"A. Bianchi Bonomi" Haemophilia and Thrombosis Centre, "Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico", Milan, Italy.

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http://dx.doi.org/10.2450/2017.0352-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839620PMC
February 2018

Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent.

Mol Nutr Food Res 2018 02 11;62(3). Epub 2017 Dec 11.

Nutrition and Genomics Laboratory, Jean Mayer-US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA.

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http://dx.doi.org/10.1002/mnfr.201700347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803424PMC
February 2018

Do Comorbidities Play a Role in Hand Osteoarthritis Disease Burden? Data from the Hand Osteoarthritis in Secondary Care Cohort.

J Rheumatol 2017 Nov 15;44(11):1659-1666. Epub 2017 Sep 15.

From the departments of Rheumatology, Radiology, and Clinical Epidemiology, Leiden University Medical Center (LUMC), Leiden, the Netherlands.

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http://dx.doi.org/10.3899/jrheum.170208DOI Listing
November 2017

Is Hepatic Triglyceride Content Associated with Aortic Pulse Wave Velocity and Carotid Intima-Media Thickness? The Netherlands Epidemiology of Obesity Study.

Radiology 2017 10 29;285(1):73-82. Epub 2017 May 29.

From the Departments of Radiology (R.L.W., J.J.M.W., A.d.R., H.J.L.), Clinical Epidemiology (R.d.M., K.B.G., M.d.H., S.l.C., F.R.R.), Internal Medicine (K.B.G.), Medical Statistics and Bio-informatics (S.l.C.), Endocrinology (R.L.W., J.W.A.S.), and Cardiology (J.W.J.), Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, the Netherlands; Department of Internal Medicine, VU University Medical Center, Amsterdam, the Netherlands (M.d.H.); and Department of Internal Medicine, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands (J.W.A.S.).

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http://dx.doi.org/10.1148/radiol.2017160916DOI Listing
October 2017

Genetic risk stratification to reduce inhibitor development in the early treatment of hemophilia A: a SIPPET analysis.

Blood 2017 10 2;130(15):1757-1759. Epub 2017 Aug 2.

Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation, Milan, Italy.

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http://dx.doi.org/10.1182/blood-2017-06-791756DOI Listing
October 2017

Association of impaired renal function with venous thrombosis: A genetic risk score approach.

Thromb Res 2017 Oct 25;158:102-107. Epub 2017 Aug 25.

Sorbonne Universités, UPMC Univ. Paris 06, Institut National pour la Santé et la Recherche Médicale (INSERM), Unité Mixte de Recherche en Santé (UMR_S) 1166, Team Genomics & Pathophysiology of Cardiovascular Diseases, Paris, France; ICAN Institute for Cardiometabolism and Nutrition, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2017.08.015DOI Listing
October 2017

Healthcare and disease burden among refugees in long-stay refugee camps at Lesbos, Greece.

Eur J Epidemiol 2017 09 8;32(9):851-854. Epub 2017 Jun 8.

Department of Clinical Epidemiology, Leiden University Medical Center, 2300RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s10654-017-0269-4DOI Listing
September 2017

Functional Impairment and Risk of Venous Thrombosis in Older Adults.

J Am Geriatr Soc 2017 Sep 9;65(9):2003-2008. Epub 2017 Jun 9.

Department of Clinical Epidemiology, Leiden University Medical Centre, Leiden, Netherlands.

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http://dx.doi.org/10.1111/jgs.14964DOI Listing
September 2017

Lipid levels and risk of venous thrombosis: results from the MEGA-study.

Eur J Epidemiol 2017 08 24;32(8):669-681. Epub 2017 May 24.

Department of Clinical Epidemiology, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s10654-017-0251-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591362PMC
August 2017

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis.

Am J Hum Genet 2017 Aug 27;101(2):227-238. Epub 2017 Jul 27.

Department of Human Genetics, McGill University, Montreal, QC H3A 1B1, Canada; Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, QC H3T 1E2, Canada; Department of Twin Research and Genetic Epidemiology, King's College London, London WC2R 2LS, UK; Department of Medicine, McGill University, Montreal, QC H3G 1Y6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544392PMC
August 2017

Statin use and risk of recurrent venous thrombosis: results from the MEGA follow-up study.

Res Pract Thromb Haemost 2017 Jul 25;1(1):112-119. Epub 2017 May 25.

Department of Clinical Epidemiology Leiden University Medical Center Leiden the Netherlands.

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http://dx.doi.org/10.1002/rth2.12003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058203PMC
July 2017

Genetic variation in the first-pass metabolism of ethinylestradiol, sex hormone binding globulin levels and venous thrombosis risk.

Eur J Intern Med 2017 Jul 1;42:54-60. Epub 2017 Jun 1.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden 2333 ZA, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ejim.2017.05.019DOI Listing
July 2017

Next-Generation Sequencing and In Vitro Expression Study of ADAMTS13 Single Nucleotide Variants in Deep Vein Thrombosis.

PLoS One 2016 1;11(11):e0165665. Epub 2016 Nov 1.

Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico and Fondazione Luigi Villa, Milan, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0165665PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089687PMC
June 2017

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.

Authors:
Felix R Day Deborah J Thompson Hannes Helgason Daniel I Chasman Hilary Finucane Patrick Sulem Katherine S Ruth Sean Whalen Abhishek K Sarkar Eva Albrecht Elisabeth Altmaier Marzyeh Amini Caterina M Barbieri Thibaud Boutin Archie Campbell Ellen Demerath Ayush Giri Chunyan He Jouke J Hottenga Robert Karlsson Ivana Kolcic Po-Ru Loh Kathryn L Lunetta Massimo Mangino Brumat Marco George McMahon Sarah E Medland Ilja M Nolte Raymond Noordam Teresa Nutile Lavinia Paternoster Natalia Perjakova Eleonora Porcu Lynda M Rose Katharina E Schraut Ayellet V Segrè Albert V Smith Lisette Stolk Alexander Teumer Irene L Andrulis Stefania Bandinelli Matthias W Beckmann Javier Benitez Sven Bergmann Murielle Bochud Eric Boerwinkle Stig E Bojesen Manjeet K Bolla Judith S Brand Hiltrud Brauch Hermann Brenner Linda Broer Thomas Brüning Julie E Buring Harry Campbell Eulalia Catamo Stephen Chanock Georgia Chenevix-Trench Tanguy Corre Fergus J Couch Diana L Cousminer Angela Cox Laura Crisponi Kamila Czene George Davey Smith Eco J C N de Geus Renée de Mutsert Immaculata De Vivo Joe Dennis Peter Devilee Isabel Dos-Santos-Silva Alison M Dunning Johan G Eriksson Peter A Fasching Lindsay Fernández-Rhodes Luigi Ferrucci Dieter Flesch-Janys Lude Franke Marike Gabrielson Ilaria Gandin Graham G Giles Harald Grallert Daniel F Gudbjartsson Pascal Guénel Per Hall Emily Hallberg Ute Hamann Tamara B Harris Catharina A Hartman Gerardo Heiss Maartje J Hooning John L Hopper Frank Hu David J Hunter M Arfan Ikram Hae Kyung Im Marjo-Riitta Järvelin Peter K Joshi David Karasik Manolis Kellis Zoltan Kutalik Genevieve LaChance Diether Lambrechts Claudia Langenberg Lenore J Launer Joop S E Laven Stefania Lenarduzzi Jingmei Li Penelope A Lind Sara Lindstrom YongMei Liu Jian'an Luan Reedik Mägi Arto Mannermaa Hamdi Mbarek Mark I McCarthy Christa Meisinger Thomas Meitinger Cristina Menni Andres Metspalu Kyriaki Michailidou Lili Milani Roger L Milne Grant W Montgomery Anna M Mulligan Mike A Nalls Pau Navarro Heli Nevanlinna Dale R Nyholt Albertine J Oldehinkel Tracy A O'Mara Sandosh Padmanabhan Aarno Palotie Nancy Pedersen Annette Peters Julian Peto Paul D P Pharoah Anneli Pouta Paolo Radice Iffat Rahman Susan M Ring Antonietta Robino Frits R Rosendaal Igor Rudan Rico Rueedi Daniela Ruggiero Cinzia F Sala Marjanka K Schmidt Robert A Scott Mitul Shah Rossella Sorice Melissa C Southey Ulla Sovio Meir Stampfer Maristella Steri Konstantin Strauch Toshiko Tanaka Emmi Tikkanen Nicholas J Timpson Michela Traglia Thérèse Truong Jonathan P Tyrer André G Uitterlinden Digna R Velez Edwards Veronique Vitart Uwe Völker Peter Vollenweider Qin Wang Elisabeth Widen Ko Willems van Dijk Gonneke Willemsen Robert Winqvist Bruce H R Wolffenbuttel Jing Hua Zhao Magdalena Zoledziewska Marek Zygmunt Behrooz Z Alizadeh Dorret I Boomsma Marina Ciullo Francesco Cucca Tõnu Esko Nora Franceschini Christian Gieger Vilmundur Gudnason Caroline Hayward Peter Kraft Debbie A Lawlor Patrik K E Magnusson Nicholas G Martin Dennis O Mook-Kanamori Ellen A Nohr Ozren Polasek David Porteous Alkes L Price Paul M Ridker Harold Snieder Tim D Spector Doris Stöckl Daniela Toniolo Sheila Ulivi Jenny A Visser Henry Völzke Nicholas J Wareham James F Wilson Amanda B Spurdle Unnur Thorsteindottir Katherine S Pollard Douglas F Easton Joyce Y Tung Jenny Chang-Claude David Hinds Anna Murray Joanne M Murabito Kari Stefansson Ken K Ong John R B Perry

Nat Genet 2017 Jun 24;49(6):834-841. Epub 2017 Apr 24.

MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.3841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841952PMC
June 2017

A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.

J Med Genet 2017 05 30;54(5):313-323. Epub 2016 Dec 30.

Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1136/jmedgenet-2016-104112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406254PMC
May 2017

Reference curves for the Australian/Canadian Hand Osteoarthritis Index in the middle-aged Dutch population.

Rheumatology (Oxford) 2017 05;56(5):745-752

Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1093/rheumatology/kew483DOI Listing
May 2017

Defining asthma-COPD overlap syndrome: a population-based study.

Eur Respir J 2017 05 1;49(5). Epub 2017 May 1.

Dept of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1183/13993003.02008-2016DOI Listing
May 2017

Liver fat: a relevant target for dietary intervention? Summary of a Unilever workshop.

J Nutr Sci 2017 8;6:e15. Epub 2017 May 8.

Department of Human Biology, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.1017/jns.2017.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468740PMC
May 2017

Control of anticoagulation with VKAs: overestimation of median TTR when assessed by linear extrapolation: A comment.

Thromb Haemost 2017 04 12;117(4):819. Epub 2017 Jan 12.

Frits R. Rosendaal, MD, PhD, Clinical Epidemiology, Leiden University Medical Center Zijllaan 44 Leiden, 2300 RC Leiden, The Netherlands, Tel.: +31 715262217, E-mail:

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http://dx.doi.org/10.1160/TH16-10-0795DOI Listing
April 2017

Nonneutralizing antibodies against factor VIII and risk of inhibitor development in severe hemophilia A.

Blood 2017 03 29;129(10):1245-1250. Epub 2016 Dec 29.

Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico Ca'Granda Ospedale Maggiore Policlinico and Luigi Villa Foundation, Milan, Italy.

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http://dx.doi.org/10.1182/blood-2016-06-720086DOI Listing
March 2017

Antibiotic use as a marker of acute infection and risk of first and recurrent venous thrombosis.

Br J Haematol 2017 03 17;176(6):961-970. Epub 2017 Feb 17.

Department of Clinical Epidemiology, Leiden University Medical Centre, Leiden, the Netherlands.

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http://dx.doi.org/10.1111/bjh.14551DOI Listing
March 2017

Thromboprophylaxis after Knee Arthroscopy and Lower-Leg Casting.

N Engl J Med 2017 02 3;376(6):515-525. Epub 2016 Dec 3.

From the Departments of Clinical Epidemiology (R.A.A., B.N., A.A., S.C., F.R.R., S.C.C.), Orthopedic Surgery (R.A.A., B.N., R.G.H.H.N.), Medical Statistics and Bioinformatics (S.C.), Trauma Surgery (I.B.S.), and Thrombosis and Hemostasis (S.C.C.), Leiden University Medical Center, Leiden, and Julius Center for Health Sciences and Patient Care, University Medical Center Utrecht, Utrecht (A.A.) - both in the Netherlands.

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February 2017

Can we prevent venous thrombosis with statins: an epidemiologic review into mechanism and clinical utility.

Expert Rev Hematol 2016 Nov 21;9(11):1023-1030. Epub 2016 Oct 21.

a Department of Clinical Epidemiology , Leiden University Medical Center , Leiden , The Netherlands.

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November 2016

Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.

Authors:
Aysu Okbay Bart M L Baselmans Jan-Emmanuel De Neve Patrick Turley Michel G Nivard Mark Alan Fontana S Fleur W Meddens Richard Karlsson Linnér Cornelius A Rietveld Jaime Derringer Jacob Gratten James J Lee Jimmy Z Liu Ronald de Vlaming Tarunveer S Ahluwalia Jadwiga Buchwald Alana Cavadino Alexis C Frazier-Wood Nicholas A Furlotte Victoria Garfield Marie Henrike Geisel Juan R Gonzalez Saskia Haitjema Robert Karlsson Sander W van der Laan Karl-Heinz Ladwig Jari Lahti Sven J van der Lee Penelope A Lind Tian Liu Lindsay Matteson Evelin Mihailov Michael B Miller Camelia C Minica Ilja M Nolte Dennis Mook-Kanamori Peter J van der Most Christopher Oldmeadow Yong Qian Olli Raitakari Rajesh Rawal Anu Realo Rico Rueedi Börge Schmidt Albert V Smith Evie Stergiakouli Toshiko Tanaka Kent Taylor Gudmar Thorleifsson Juho Wedenoja Juergen Wellmann Harm-Jan Westra Sara M Willems Wei Zhao Najaf Amin Andrew Bakshi Sven Bergmann Gyda Bjornsdottir Patricia A Boyle Samantha Cherney Simon R Cox Gail Davies Oliver S P Davis Jun Ding Nese Direk Peter Eibich Rebecca T Emeny Ghazaleh Fatemifar Jessica D Faul Luigi Ferrucci Andreas J Forstner Christian Gieger Richa Gupta Tamara B Harris Juliette M Harris Elizabeth G Holliday Jouke-Jan Hottenga Philip L De Jager Marika A Kaakinen Eero Kajantie Ville Karhunen Ivana Kolcic Meena Kumari Lenore J Launer Lude Franke Ruifang Li-Gao David C Liewald Marisa Koini Anu Loukola Pedro Marques-Vidal Grant W Montgomery Miriam A Mosing Lavinia Paternoster Alison Pattie Katja E Petrovic Laura Pulkki-Råback Lydia Quaye Katri Räikkönen Igor Rudan Rodney J Scott Jennifer A Smith Angelina R Sutin Maciej Trzaskowski Anna E Vinkhuyzen Lei Yu Delilah Zabaneh John R Attia David A Bennett Klaus Berger Lars Bertram Dorret I Boomsma Harold Snieder Shun-Chiao Chang Francesco Cucca Ian J Deary Cornelia M van Duijn Johan G Eriksson Ute Bültmann Eco J C de Geus Patrick J F Groenen Vilmundur Gudnason Torben Hansen Catharine A Hartman Claire M A Haworth Caroline Hayward Andrew C Heath David A Hinds Elina Hyppönen William G William Marjo-Riitta Järvelin Karl-Heinz Jöckel Jaakko Kaprio Sharon L R Kardia Liisa Keltikangas-Järvinen Peter Kraft Laura D Kubzansky Terho Lehtimäki Patrik K E Magnusson Nicholas G Martin Matt McGue Andres Metspalu Melinda Mills Renée de Mutsert Albertine J Oldehinkel Gerard Pasterkamp Nancy L Pedersen Robert Plomin Ozren Polasek Christine Power Stephen S Rich Frits R Rosendaal Hester M den Ruijter David Schlessinger Helena Schmidt Rauli Svento Reinhold Schmidt Behrooz Z Alizadeh Thorkild I A Sørensen Tim D Spector John M Starr Kari Stefansson Andrew Steptoe Antonio Terracciano Unnur Thorsteinsdottir A Roy Thurik Nicholas J Timpson Henning Tiemeier André G Uitterlinden Peter Vollenweider Gert G Wagner David R Weir Jian Yang Dalton C Conley George Davey Smith Albert Hofman Magnus Johannesson David I Laibson Sarah E Medland Michelle N Meyer Joseph K Pickrell Tõnu Esko Robert F Krueger Jonathan P Beauchamp Philipp D Koellinger Daniel J Benjamin Meike Bartels David Cesarini

Nat Genet 2016 11;48(12):1591

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http://dx.doi.org/10.1038/ng1216-1587bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509058PMC
November 2016

Genome-wide associations for birth weight and correlations with adult disease.

Authors:
Momoko Horikoshi Robin N Beaumont Felix R Day Nicole M Warrington Marjolein N Kooijman Juan Fernandez-Tajes Bjarke Feenstra Natalie R van Zuydam Kyle J Gaulton Niels Grarup Jonathan P Bradfield David P Strachan Ruifang Li-Gao Tarunveer S Ahluwalia Eskil Kreiner Rico Rueedi Leo-Pekka Lyytikäinen Diana L Cousminer Ying Wu Elisabeth Thiering Carol A Wang Christian T Have Jouke-Jan Hottenga Natalia Vilor-Tejedor Peter K Joshi Eileen Tai Hui Boh Ioanna Ntalla Niina Pitkänen Anubha Mahajan Elisabeth M van Leeuwen Raimo Joro Vasiliki Lagou Michael Nodzenski Louise A Diver Krina T Zondervan Mariona Bustamante Pedro Marques-Vidal Josep M Mercader Amanda J Bennett Nilufer Rahmioglu Dale R Nyholt Ronald Ching Wan Ma Claudia Ha Ting Tam Wing Hung Tam Santhi K Ganesh Frank Ja van Rooij Samuel E Jones Po-Ru Loh Katherine S Ruth Marcus A Tuke Jessica Tyrrell Andrew R Wood Hanieh Yaghootkar Denise M Scholtens Lavinia Paternoster Inga Prokopenko Peter Kovacs Mustafa Atalay Sara M Willems Kalliope Panoutsopoulou Xu Wang Lisbeth Carstensen Frank Geller Katharina E Schraut Mario Murcia Catharina Em van Beijsterveldt Gonneke Willemsen Emil V R Appel Cilius E Fonvig Caecilie Trier Carla Mt Tiesler Marie Standl Zoltán Kutalik Sílvia Bonas-Guarch David M Hougaard Friman Sánchez David Torrents Johannes Waage Mads V Hollegaard Hugoline G de Haan Frits R Rosendaal Carolina Medina-Gomez Susan M Ring Gibran Hemani George McMahon Neil R Robertson Christopher J Groves Claudia Langenberg Jian'an Luan Robert A Scott Jing Hua Zhao Frank D Mentch Scott M MacKenzie Rebecca M Reynolds William L Lowe Anke Tönjes Michael Stumvoll Virpi Lindi Timo A Lakka Cornelia M van Duijn Wieland Kiess Antje Körner Thorkild Ia Sørensen Harri Niinikoski Katja Pahkala Olli T Raitakari Eleftheria Zeggini George V Dedoussis Yik-Ying Teo Seang-Mei Saw Mads Melbye Harry Campbell James F Wilson Martine Vrijheid Eco Jcn de Geus Dorret I Boomsma Haja N Kadarmideen Jens-Christian Holm Torben Hansen Sylvain Sebert Andrew T Hattersley Lawrence J Beilin John P Newnham Craig E Pennell Joachim Heinrich Linda S Adair Judith B Borja Karen L Mohlke Johan G Eriksson Elisabeth E Widén Mika Kähönen Jorma S Viikari Terho Lehtimäki Peter Vollenweider Klaus Bønnelykke Hans Bisgaard Dennis O Mook-Kanamori Albert Hofman Fernando Rivadeneira André G Uitterlinden Charlotta Pisinger Oluf Pedersen Christine Power Elina Hyppönen Nicholas J Wareham Hakon Hakonarson Eleanor Davies Brian R Walker Vincent Wv Jaddoe Marjo-Riitta Jarvelin Struan Fa Grant Allan A Vaag Debbie A Lawlor Timothy M Frayling George Davey Smith Andrew P Morris Ken K Ong Janine F Felix Nicholas J Timpson John Rb Perry David M Evans Mark I McCarthy Rachel M Freathy

Nature 2016 10 28;538(7624):248-252. Epub 2016 Sep 28.

Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Exeter, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5164934PMC
October 2016

Joint effects of cancer and variants in the factor 5 gene on the risk of venous thromboembolism.

Haematologica 2016 09 16;101(9):1046-53. Epub 2016 Jun 16.

K.G. Jebsen Thrombosis Research and Expertise Center (TREC), Department of Clinical Medicine, UiT -The Arctic University of Norway, Tromsø, Norway Division of Internal Medicine, University Hospital of North Norway, Tromsø, Norway.

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http://dx.doi.org/10.3324/haematol.2016.147405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5060021PMC
September 2016

Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.

Authors:
Aysu Okbay Bart M L Baselmans Jan-Emmanuel De Neve Patrick Turley Michel G Nivard Mark Alan Fontana S Fleur W Meddens Richard Karlsson Linnér Cornelius A Rietveld Jaime Derringer Jacob Gratten James J Lee Jimmy Z Liu Ronald de Vlaming Tarunveer S Ahluwalia Jadwiga Buchwald Alana Cavadino Alexis C Frazier-Wood Nicholas A Furlotte Victoria Garfield Marie Henrike Geisel Juan R Gonzalez Saskia Haitjema Robert Karlsson Sander W van der Laan Karl-Heinz Ladwig Jari Lahti Sven J van der Lee Penelope A Lind Tian Liu Lindsay Matteson Evelin Mihailov Michael B Miller Camelia C Minica Ilja M Nolte Dennis Mook-Kanamori Peter J van der Most Christopher Oldmeadow Yong Qian Olli Raitakari Rajesh Rawal Anu Realo Rico Rueedi Börge Schmidt Albert V Smith Evie Stergiakouli Toshiko Tanaka Kent Taylor Gudmar Thorleifsson Juho Wedenoja Juergen Wellmann Harm-Jan Westra Sara M Willems Wei Zhao Najaf Amin Andrew Bakshi Sven Bergmann Gyda Bjornsdottir Patricia A Boyle Samantha Cherney Simon R Cox Gail Davies Oliver S P Davis Jun Ding Nese Direk Peter Eibich Rebecca T Emeny Ghazaleh Fatemifar Jessica D Faul Luigi Ferrucci Andreas J Forstner Christian Gieger Richa Gupta Tamara B Harris Juliette M Harris Elizabeth G Holliday Jouke-Jan Hottenga Philip L De Jager Marika A Kaakinen Eero Kajantie Ville Karhunen Ivana Kolcic Meena Kumari Lenore J Launer Lude Franke Ruifang Li-Gao David C Liewald Marisa Koini Anu Loukola Pedro Marques-Vidal Grant W Montgomery Miriam A Mosing Lavinia Paternoster Alison Pattie Katja E Petrovic Laura Pulkki-Råback Lydia Quaye Katri Räikkönen Igor Rudan Rodney J Scott Jennifer A Smith Angelina R Sutin Maciej Trzaskowski Anna E Vinkhuyzen Lei Yu Delilah Zabaneh John R Attia David A Bennett Klaus Berger Lars Bertram Dorret I Boomsma Harold Snieder Shun-Chiao Chang Francesco Cucca Ian J Deary Cornelia M van Duijn Johan G Eriksson Ute Bültmann Eco J C de Geus Patrick J F Groenen Vilmundur Gudnason Torben Hansen Catharine A Hartman Claire M A Haworth Caroline Hayward Andrew C Heath David A Hinds Elina Hyppönen William G Iacono Marjo-Riitta Järvelin Karl-Heinz Jöckel Jaakko Kaprio Sharon L R Kardia Liisa Keltikangas-Järvinen Peter Kraft Laura D Kubzansky Terho Lehtimäki Patrik K E Magnusson Nicholas G Martin Matt McGue Andres Metspalu Melinda Mills Renée de Mutsert Albertine J Oldehinkel Gerard Pasterkamp Nancy L Pedersen Robert Plomin Ozren Polasek Christine Power Stephen S Rich Frits R Rosendaal Hester M den Ruijter David Schlessinger Helena Schmidt Rauli Svento Reinhold Schmidt Behrooz Z Alizadeh Thorkild I A Sørensen Tim D Spector John M Starr Kari Stefansson Andrew Steptoe Antonio Terracciano Unnur Thorsteinsdottir A Roy Thurik Nicholas J Timpson Henning Tiemeier André G Uitterlinden Peter Vollenweider Gert G Wagner David R Weir Jian Yang Dalton C Conley George Davey Smith Albert Hofman Magnus Johannesson David I Laibson Sarah E Medland Michelle N Meyer Joseph K Pickrell Tõnu Esko Robert F Krueger Jonathan P Beauchamp Philipp D Koellinger Daniel J Benjamin Meike Bartels David Cesarini

Nat Genet 2016 07;48(8):970

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July 2016

A Randomized Trial of Factor VIII and Neutralizing Antibodies in Hemophilia A.

N Engl J Med 2016 May;374(21):2054-64

From the Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda Ospedale Maggiore Policlinico (F.P., P.M.M., E.S., M.E.M.), and Department of Pathophysiology and Transplantation, Università degli Studi di Milano (F.P., P.M.M., I.G.), Milan, Clinica Medica II, Azienda Ospedaliera di Padova, Centro Emofilia, Padua (E.Z.), and Ematologia, Unità Operativa Diagnostica Speciale e Terapia delle Malattie dell'Emostasi e della Trombosi, Università Sapienza, Policlinico Umberto I, Rome (M.G.M.) - all in Italy; the Pediatric Hematology Department, Cairo University Pediatric Hospital (A.E.-B.), and Department of Pediatrics, Faculty of Medicine, Ain Shams University (M.E.), Cairo; Jehangir Clinical Development Center, Department of Hematology, Jehangir Hospital Premises (V.R.), and Sahyadri Speciality Hospital (S.A.), Pune, Jagadguru Jayadeva Murugarajendra Medical College, Davangere (S.H.), Center for Blood Disorders, Chennai (R.V.), Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai (M.V.M.); St. John's Medical College Hospital, Bangalore (C.R.), All India Institute of Medical Sciences, Department of Hematology (T.S.), and Pediatric Hematology Oncology and Bone Marrow Transplantation, Institute for Child Health, Sir Ganga Ram Hospital (A.S.), New Delhi, Melaka-Manipal Medical College, Manipal University, Manipal (D.M.N.), and Kerala Institute of Medical Science, Trivandrum (M.T.) - all in India; the Congenital Pediatric Hematologic Disorders Research Center, Shahid Beheshti University of Medical Sciences, Tehran (P.E.), and Hematology Research Center, Shiraz University of Medical Sciences, Shiraz (M.K.) - both in Iran; Children's Hospital Los Angeles, Los Angeles (G.Y.), and City of Hope National Medical Center, Duarte (N.P.E.) - both in California; Hospital de Especialidades Unidad Médica de Alta Especialidad, Instituto Mexicano del Seguro Social, Monterrey (A.C.S.G.), an

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http://dx.doi.org/10.1056/NEJMoa1516437DOI Listing
May 2016