Frits Koning

Frits Koning

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Frits Koning

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Update 2020: nomenclature and listing of celiac disease-relevant gluten epitopes recognized by CD4 T cells.

Immunogenetics 2020 02 18;72(1-2):85-88. Epub 2019 Nov 18.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00251-019-01141-wDOI Listing
February 2020

T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease.

Nat Struct Mol Biol 2020 Jan 23;27(1):49-61. Epub 2019 Dec 23.

Infection and Immunity Program and The Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1038/s41594-019-0353-4DOI Listing
January 2020

Narcolepsy - clinical spectrum, aetiopathophysiology, diagnosis and treatment.

Nat Rev Neurol 2019 09 19;15(9):519-539. Epub 2019 Jul 19.

Sleep-Wake Disorders Center, Department of Neurology, Gui-de-Chauliac Hospital, CHU Montpellier, University of Montpellier, Montpellier, France.

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http://dx.doi.org/10.1038/s41582-019-0226-9DOI Listing
September 2019

Safety Assessment of Immune-Mediated Adverse Reactions to Novel Food Proteins.

Trends Biotechnol 2019 Aug 17;37(8):796-800. Epub 2019 Apr 17.

Instituto de Investigación en Ciencias de la Alimentación, CIAL (CSIC-UAM), C/ Nicolás Cabrera, 9, Campus de la Universidad Autónoma de Madrid, 28049 Madrid, Spain.

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http://dx.doi.org/10.1016/j.tibtech.2019.03.010DOI Listing
August 2019

PD-L1 blockade engages tumor-infiltrating lymphocytes to co-express targetable activating and inhibitory receptors.

J Immunother Cancer 2019 Aug 14;7(1):217. Epub 2019 Aug 14.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Albinusdreef 2, 2333, ZA, Leiden, The Netherlands.

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http://dx.doi.org/10.1186/s40425-019-0700-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694641PMC
August 2019

Predicting Cell Populations in Single Cell Mass Cytometry Data.

Cytometry A 2019 Jul 12;95(7):769-781. Epub 2019 Mar 12.

Delft Bioinformatics Lab, Delft University of Technology, Delft 2628 XE, The Netherlands.

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http://doi.wiley.com/10.1002/cyto.a.23738
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http://dx.doi.org/10.1002/cyto.a.23738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767556PMC
July 2019

CyteGuide: Visual Guidance for Hierarchical Single-Cell Analysis.

IEEE Trans Vis Comput Graph 2018 01 29;24(1):739-748. Epub 2017 Aug 29.

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http://dx.doi.org/10.1109/TVCG.2017.2744318DOI Listing
January 2018

A Specialist Macaque MHC Class I Molecule with HLA-B*27-like Peptide-Binding Characteristics.

J Immunol 2017 11 11;199(10):3679-3690. Epub 2017 Oct 11.

Department of Comparative Genetics and Refinement, Biomedical Primate Research Centre, 2288 GJ Rijswijk, the Netherlands.

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http://dx.doi.org/10.4049/jimmunol.1700502DOI Listing
November 2017

Visual analysis of mass cytometry data by hierarchical stochastic neighbour embedding reveals rare cell types.

Nat Commun 2017 11 23;8(1):1740. Epub 2017 Nov 23.

Pattern Recognition and Bioinformatics Group, Delft University of Technology, Mekelweg 4, 2628, CD, Delft, The Netherlands.

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http://dx.doi.org/10.1038/s41467-017-01689-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700955PMC
November 2017

Hybrid Imaging Labels: Providing the Link Between Mass Spectrometry-Based Molecular Pathology and Theranostics.

Theranostics 2017 12;7(3):624-633. Epub 2017 Jan 12.

Interventional Molecular Imaging laboratory, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands;; Laboratory of BioNanoTechnology, Wageningen University, Wageningen, the Netherlands.

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http://dx.doi.org/10.7150/thno.17484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5327638PMC
October 2017

Abrogation of Immunogenic Properties of Gliadin Peptides through Transamidation by Microbial Transglutaminase Is Acyl-Acceptor Dependent.

J Agric Food Chem 2017 Aug 17;65(34):7542-7552. Epub 2017 Aug 17.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center , Leiden 2333 ZA, The Netherlands.

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http://dx.doi.org/10.1021/acs.jafc.7b02557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579586PMC
August 2017

Weight loss induced by very low calorie diet is associated with a more beneficial systemic inflammatory profile than by Roux-en-Y gastric bypass.

Metabolism 2016 Nov 16;65(11):1614-1620. Epub 2016 Aug 16.

Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, the Netherlands; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2016.07.013DOI Listing
November 2016

Diverse T Cell Receptor Gene Usage in HLA-DQ8-Associated Celiac Disease Converges into a Consensus Binding Solution.

Structure 2016 10 25;24(10):1643-1657. Epub 2016 Aug 25.

Infection and Immunity Program, The Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, VIC 3800, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.str.2016.07.010DOI Listing
October 2016

Adverse Effects of Wheat Gluten.

Authors:
Frits Koning

Ann Nutr Metab 2015 26;67 Suppl 2:8-14. Epub 2015 Nov 26.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1159/000440989DOI Listing
September 2016

Isolation and Cloning of Gluten-Specific T Cells in Celiac Disease.

Methods Mol Biol 2015 ;1326:53-9

Department of Immunohematology and Blood Transfusion, Leiden University Medical Centre, E3-Q, 9600, 2300 RC, Leiden, The Netherlands.

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http://link.springer.com/10.1007/978-1-4939-2839-2_6
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http://dx.doi.org/10.1007/978-1-4939-2839-2_6DOI Listing
August 2016

Mass Cytometry of the Human Mucosal Immune System Identifies Tissue- and Disease-Associated Immune Subsets.

Immunity 2016 05 10;44(5):1227-39. Epub 2016 May 10.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.04.014DOI Listing
May 2016

Ineffective degradation of immunogenic gluten epitopes by currently available digestive enzyme supplements.

PLoS One 2015 1;10(6):e0128065. Epub 2015 Jun 1.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Centre, Leiden, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0128065PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452362PMC
February 2016

Therapy in RCDII: Rationale for Combination Strategies?

Dig Dis 2015 22;33(2):227-30. Epub 2015 Apr 22.

Department of Gastroenterology, VU University Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1159/000381076DOI Listing
January 2016

Recent insight in the pathophysiology of coeliac disease: relevance to rheumatoid arthritis.

Authors:
Frits Koning

Clin Exp Rheumatol 2015 Jul-Aug;33(4 Suppl 92):S8-10. Epub 2015 Oct 12.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.

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December 2015

FcRγ-chain deficiency reduces the development of diet-induced obesity.

Obesity (Silver Spring) 2015 Dec 2;23(12):2435-44. Epub 2015 Nov 2.

Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1002/oby.21309DOI Listing
December 2015

Coeliac disease and gluten-related disorders in childhood.

Nat Rev Gastroenterol Hepatol 2015 Sep 23;12(9):527-36. Epub 2015 Jun 23.

Department of Paediatrics, Leiden University Medical Centre, Albinusdreef 2/PO 9600, 2300 RC Leiden, Netherlands.

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http://www.nature.com/articles/nrgastro.2015.98
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http://dx.doi.org/10.1038/nrgastro.2015.98DOI Listing
September 2015

Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens.

Nat Rev Rheumatol 2015 Aug 19;11(8):450-61. Epub 2015 May 19.

Department of Rheumatology, Leiden University Medical Centre, Albinusdreef 2, Leiden 2333 ZA, Netherlands.

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http://dx.doi.org/10.1038/nrrheum.2015.59DOI Listing
August 2015

The Probiotic Mixture VSL#3 Has Differential Effects on Intestinal Immune Parameters in Healthy Female BALB/c and C57BL/6 Mice.

J Nutr 2015 Jun 6;145(6):1354-61. Epub 2015 May 6.

Department of Metabolic Health Research, TNO, Leiden, The Netherlands; and.

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http://dx.doi.org/10.3945/jn.114.199729DOI Listing
June 2015

Determinants of gliadin-specific T cell selection in celiac disease.

J Immunol 2015 Jun 6;194(12):6112-22. Epub 2015 May 6.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden 2333 ZA, the Netherlands;

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http://dx.doi.org/10.4049/jimmunol.1500161DOI Listing
June 2015

Preface.

Authors:
Frits Koning

Best Pract Res Clin Gastroenterol 2015 Jun 12;29(3):363. Epub 2015 May 12.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Centre, 2300 RC Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bpg.2015.05.002DOI Listing
June 2015

Influence of dietary components on Aspergillus niger prolyl endoprotease mediated gluten degradation.

Food Chem 2015 May 14;174:440-5. Epub 2014 Nov 14.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S03088146140178
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http://dx.doi.org/10.1016/j.foodchem.2014.11.053DOI Listing
May 2015

Local communication among mucosal immune cells in patients with celiac disease.

Gastroenterology 2015 May 24;148(6):1187-94. Epub 2015 Jan 24.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2015.01.030DOI Listing
May 2015

The probiotic mixture VSL#3 mediates both pro- and anti-inflammatory responses in bone marrow-derived dendritic cells from C57BL/6 and BALB/c mice.

Br J Nutr 2014 Oct 2;112(7):1088-97. Epub 2014 Sep 2.

Department of Metabolic Health Research,TNO,Zernikedreef 9, 2333 CK,Leiden,The Netherlands.

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http://dx.doi.org/10.1017/S000711451400169XDOI Listing
October 2014

Celiac disease: past, present, and future challenges: dedicated to the memory of our friend and colleague, Prof David Branski (1944-2013).

J Pediatr Gastroenterol Nutr 2014 Jul;59 Suppl 1:S1-20

*Institute of Gastroenterology, Nutrition, and Liver Diseases, Schneider Children's Medical Center of Israel, Petach Tikva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel †Division of Pediatrics, Gastroenterology, and Nutrition, University of California, San Francisco ‡Leiden University Medical Centre, Leiden, The Netherlands §University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands ||Department of Pediatrics, Università Politecnica delle Marche, Ancona, Italy ¶Center for Celiac Research, Massachustetts General Hospital for Children and Celiac Program at Harvard Medical School, Boston, MA #Department of Medical Translational Sciences and European Laboratory for the Investigation of Food Induced Diseases, University Federico II, Naples, Italy **Department of Medicine and the University of Chicago Celiac Disease Center, University of Chicago, Chicago, IL ††Department of Pediatrics, University of Debrecen, Debrecen, and Celiac Disease Center, Heim Pal Children's Hospital, Budapest, Hungary ‡‡Tampere Center for Child Health Research, University of Tampere and Tampere University Hospital, Tampere, Finland §§Unit of Pediatric Gastroenterology, Department of Pediatrics, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1097/MPG.0000000000000410DOI Listing
July 2014

Pathophysiology of celiac disease.

Authors:
Frits Koning

J Pediatr Gastroenterol Nutr 2014 Jul;59 Suppl 1:S1-4

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/01.mpg.0000450391.46027.48DOI Listing
July 2014

T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease.

Nat Struct Mol Biol 2014 May 28;21(5):480-8. Epub 2014 Apr 28.

1] Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria, Australia. [2] Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK. [3] Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, Victoria, Australia. [4] [5].

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http://dx.doi.org/10.1038/nsmb.2817DOI Listing
May 2014

Increased systemic and adipose tissue inflammation differentiates obese women with T2DM from obese women with normal glucose tolerance.

Metabolism 2014 Apr 10;63(4):492-501. Epub 2013 Dec 10.

Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2013.12.002DOI Listing
April 2014

Dendritic cells promote expansion and survival of aberrant TCR-negative intraepithelial lymphocyte lines from refractory celiac disease type II patients.

Mol Immunol 2014 Mar 16;58(1):10-6. Epub 2013 Nov 16.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2013.10.014DOI Listing
March 2014

Unique peptide-binding motif for Mamu-B*037:01: an MHC class I allele common to Indian and Chinese rhesus macaques.

Immunogenetics 2013 Dec 17;65(12):897-900. Epub 2013 Sep 17.

Comparative Genetics and Refinement, Biomedical Primate Research Centre, 2288 GJ, Rijswijk, The Netherlands,

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http://dx.doi.org/10.1007/s00251-013-0734-5DOI Listing
December 2013

Consumption of gluten with gluten-degrading enzyme by celiac patients: a pilot-study.

World J Gastroenterol 2013 Sep;19(35):5837-47

Greetje J Tack, Jolanda MW van de Water, Chris J Mulder, Department of Gastroenterology and Hepatology, VU University Medical Centre, 1007 MB Amsterdam, The Netherlands.

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http://dx.doi.org/10.3748/wjg.v19.i35.5837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793137PMC
September 2013

HLA reduces killer cell Ig-like receptor expression level and frequency in a humanized mouse model.

J Immunol 2013 Mar 6;190(6):2880-5. Epub 2013 Feb 6.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.

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http://dx.doi.org/10.4049/jimmunol.1200650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197943PMC
March 2013

The million-dollar question: is "gluten-free" food safe for patients with celiac disease?

Am J Clin Nutr 2013 Jan 5;97(1):3-4. Epub 2012 Dec 5.

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http://dx.doi.org/10.3945/ajcn.112.053777DOI Listing
January 2013

Gene expression profiling identifies mechanisms of protection to recurrent trinitrobenzene sulfonic acid colitis mediated by probiotics.

Inflamm Bowel Dis 2012 Aug 11;18(8):1424-33. Epub 2011 Dec 11.

Department of Metabolic Health Research, TNO, Leiden, The Netherlands.

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http://dx.doi.org/10.1002/ibd.22849DOI Listing
August 2012

Celiac disease: quantity matters.

Authors:
Frits Koning

Semin Immunopathol 2012 Jul 26;34(4):541-9. Epub 2012 Jun 26.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, E3-Q, PO box 9600, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00281-012-0321-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410019PMC
July 2012

Nomenclature and listing of celiac disease relevant gluten T-cell epitopes restricted by HLA-DQ molecules.

Immunogenetics 2012 Jun 10;64(6):455-60. Epub 2012 Feb 10.

Centre for Immune Regulation and Department of Immunology, University of Oslo and Oslo University Hospital, Rikshospitalet, Oslo, Norway.

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http://link.springer.com/10.1007/s00251-012-0599-z
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http://dx.doi.org/10.1007/s00251-012-0599-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349865PMC
June 2012

Origin and immunophenotype of aberrant IEL in RCDII patients.

Mol Immunol 2012 Apr 23;50(4):262-70. Epub 2012 Feb 23.

Gastroenterology and Hepatology, VU University Medical Center, The Netherlands.

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http://dx.doi.org/10.1016/j.molimm.2012.01.014DOI Listing
April 2012

Screening for unrecognized coeliac disease in subfertile couples.

Scand J Gastroenterol 2011 Dec 12;46(12):1423-8. Epub 2011 Sep 12.

Department of Paediatric Gastroenterology, Leiden University Medical Center, Leiden, Netherlands.

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http://dx.doi.org/10.3109/00365521.2011.615858DOI Listing
December 2011

Gluten-specific T cells cross-react between HLA-DQ8 and the HLA-DQ2α/DQ8β transdimer.

J Immunol 2011 Nov 17;187(10):5123-9. Epub 2011 Oct 17.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1101179
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http://dx.doi.org/10.4049/jimmunol.1101179DOI Listing
November 2011

Tolerance to ingested deamidated gliadin in mice is maintained by splenic, type 1 regulatory T cells.

Gastroenterology 2011 Aug 28;141(2):610-20, 620.e1-2. Epub 2011 Apr 28.

Department of Pediatrics, Erasmus Medical Center - Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1053/j.gastro.2011.04.048DOI Listing
August 2011

Successful treatment of coeliac disease by allogeneic haematopoietic stem cell transplantation.

J Pediatr Gastroenterol Nutr 2010 Dec;51(6):793-4

Department of Paediatrics, Hieronymus Bosch Hospital, 's-Hertogenbosch, The Netherlands.

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https://insights.ovid.com/crossref?an=00005176-201012000-000
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http://dx.doi.org/10.1097/MPG.0b013e3181edf35bDOI Listing
December 2010

The PreventCD Study design: towards new strategies for the prevention of coeliac disease.

Eur J Gastroenterol Hepatol 2010 Dec;22(12):1424-30

Department of Pediatric Gastroenterology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1097/MEG.0b013e32833fe9aeDOI Listing
December 2010

The tortoise and the hare: slowly evolving T-cell responses take hastily evolving KIR.

Immunology 2010 Nov 17;131(3):301-9. Epub 2010 Aug 17.

Department of Immunohaematology and Blood Transfusion, Leiden University Medical Centre, Leiden, the Netherlands.

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http://doi.wiley.com/10.1111/j.1365-2567.2010.03337.x
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http://dx.doi.org/10.1111/j.1365-2567.2010.03337.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996550PMC
November 2010

Celiac disease: how complicated can it get?

Immunogenetics 2010 Oct 27;62(10):641-51. Epub 2010 Jul 27.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, RC Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00251-010-0465-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2944025PMC
October 2010

Design of new high-affinity peptide ligands for human leukocyte antigen-DQ2 using a positional scanning peptide library.

Hum Immunol 2010 May 6;71(5):475-81. Epub 2010 Feb 6.

Centre for Immune Regulation, Institute of Immunology, Oslo University Hospital-Rikshospitalet, 0027 Oslo, Norway.

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http://dx.doi.org/10.1016/j.humimm.2010.01.021DOI Listing
May 2010

Design, synthesis and evaluation of high-affinity binders for the celiac disease associated HLA-DQ2 molecule.

Mol Immunol 2010 Feb 3;47(5):1091-7. Epub 2009 Dec 3.

Leiden Institute of Chemistry, Gorlaeus Laboratories, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.molimm.2009.10.036DOI Listing
February 2010

Evidence for natural killer cell-mediated protection from metastasis formation in uveal melanoma patients.

Invest Ophthalmol Vis Sci 2009 Jun 21;50(6):2888-95. Epub 2009 Feb 21.

Department of Ophthalmology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1167/iovs.08-2733DOI Listing
June 2009

Functional killer Ig-like receptors on human memory CD4+ T cells specific for cytomegalovirus.

J Immunol 2009 Apr;182(7):4175-82

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, the Netherlands.

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http://dx.doi.org/10.4049/jimmunol.0800455DOI Listing
April 2009

Phenotypic variance in childhood coeliac disease and the HLA-DQ/DR dose effect.

Scand J Gastroenterol 2009 ;44(1):40-5

Department of Paediatric Gastroenterology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1080/00365520802116422DOI Listing
March 2009

Cutting edge: killer Ig-like receptors mediate "missing self" recognition in vivo.

J Immunol 2009 Mar;182(5):2569-72

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.4049/jimmunol.0804042DOI Listing
March 2009

Fine specificity of monoclonal antibodies against celiac disease-inducing peptides in the gluteome.

Am J Clin Nutr 2008 Oct;88(4):1057-66

Department of Blood Transfusion and Immunohematology, Leiden University Medical Center, Leiden, Netherlands.

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http://dx.doi.org/10.1093/ajcn/88.4.1057DOI Listing
October 2008

Dominance of an alternative CLIP sequence in the celiac disease associated HLA-DQ2 molecule.

Immunogenetics 2008 Sep 27;60(9):551-5. Epub 2008 Jun 27.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Centre, Leiden, The Netherlands.

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http://link.springer.com/10.1007/s00251-008-0310-6
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http://dx.doi.org/10.1007/s00251-008-0310-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491419PMC
September 2008

Mannosylated self-peptide inhibits the development of experimental autoimmune encephalomyelitis via expansion of nonencephalitogenic T cells.

J Leukoc Biol 2008 Jul 18;84(1):182-90. Epub 2008 Apr 18.

Business Unit Biosciences, TNO Quality of Life, Leiden, The Netherlands.

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http://dx.doi.org/10.1189/jlb.0507312DOI Listing
July 2008

Gluten tolerance in adult patients with celiac disease 20 years after diagnosis?

Eur J Gastroenterol Hepatol 2008 May;20(5):423-9

Department of Dietetics and Nutrition, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1097/MEG.0b013e3282f4de6eDOI Listing
May 2008

Celiac disease: sandwiched between innate and adaptive immune responses induced by gluten.

Authors:
Frits Koning

J Pediatr Gastroenterol Nutr 2008 Apr;46 Suppl 1:E8-9

Leiden University Medical Centre, Leiden, The Netherlands.

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https://insights.ovid.com/crossref?an=00005176-200804001-000
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http://dx.doi.org/10.1097/01.mpg.0000313820.04144.98DOI Listing
April 2008

Tef in the diet of celiac patients in The Netherlands.

Scand J Gastroenterol 2008 Mar;43(3):277-82

Department of Dietetics and Nutrition, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1080/00365520701714871DOI Listing
March 2008

Large-scale characterization of natural ligands explains the unique gluten-binding properties of HLA-DQ2.

J Immunol 2008 Mar;180(5):3268-78

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.4049/jimmunol.180.5.3268DOI Listing
March 2008

Design of azidoproline containing gluten peptides to suppress CD4+ T-cell responses associated with celiac disease.

Bioorg Med Chem 2008 Feb 4;16(4):2053-62. Epub 2007 Nov 4.

Bioorganic Synthesis, Leiden Institute of Chemistry, Leiden University, Einsteinweg 55, 2300 RA, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.bmc.2007.10.091DOI Listing
February 2008

Immunization with mannosylated peptide induces poor T cell effector functions despite enhanced antigen presentation.

Int Immunol 2008 Jan 15;20(1):117-27. Epub 2007 Nov 15.

Business Unit Biosciences, TNO Quality of Life, Zernikedreef 9, 2333 CK Leiden, The Netherlands.

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https://academic.oup.com/intimm/article-lookup/doi/10.1093/i
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http://dx.doi.org/10.1093/intimm/dxm123DOI Listing
January 2008

A tertiary twist to the transglutaminase tale.

Authors:
Frits Koning

PLoS Biol 2007 Dec;5(12):e337

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.

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https://dx.plos.org/10.1371/journal.pbio.0050337
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222976PMC
December 2007

Enzymatic gluten detoxification: the proof of the pudding is in the eating!

Trends Biotechnol 2006 Oct 23;24(10):433-4. Epub 2006 Aug 23.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S016777990600207
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http://dx.doi.org/10.1016/j.tibtech.2006.08.003DOI Listing
October 2006

Genetic and functional analysis of pyroglutamyl-peptidase I in coeliac disease.

Eur J Gastroenterol Hepatol 2006 Jun;18(6):637-44

Complex Genetics Section, DBG-Department of Medical Genetics, University Medical Centre, Utrecht, the Netherlands.

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http://dx.doi.org/10.1097/00042737-200606000-00010DOI Listing
June 2006

Celiac disease--sandwiched between innate and adaptive immunity.

Hum Immunol 2006 Jun 30;67(6):460-8. Epub 2006 Mar 30.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Centre, The Netherlands.

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June 2006