Friederike Flachsbart

Friederike Flachsbart

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Friederike Flachsbart

Friederike Flachsbart

Publications by authors named "Friederike Flachsbart"

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32Publications

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On a Western diet, APOEɛ4 is associated with low innate immune sensing, but not APOEɛ3.

J Allergy Clin Immunol 2018 10 19;142(4):1346-1349.e9. Epub 2018 Jun 19.

Institute of Human Nutrition and Food Science, Kiel University, Kiel, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.05.033DOI Listing
October 2018

Human longevity and variation in DNA damage response and repair: study of the contribution of sub-processes using competitive gene-set analysis.

Eur J Hum Genet 2014 Sep 12;22(9):1131-6. Epub 2014 Feb 12.

1] Epidemiology, Biostatistics and Biodemography, The Danish Aging Research Center, Institute of Public Health, University of Southern Denmark, Odense, Denmark [2] Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.

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http://www.ideal-ageing.eu/uploads/publicaties/2014/2014_deb
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http://www.nature.com/doifinder/10.1038/ejhg.2013.299
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http://dx.doi.org/10.1038/ejhg.2013.299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135411PMC
September 2014

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

Hum Mol Genet 2014 Aug 31;23(16):4420-32. Epub 2014 Mar 31.

Department of Molecular Epidemiology, Netherlands Consortium for Healthy Ageing,

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http://dx.doi.org/10.1093/hmg/ddu139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103672PMC
August 2014

Adjustment for smoking does not alter the FOXO3A association with longevity.

Age (Dordr) 2014 Apr 7;36(2):911-21. Epub 2013 Sep 7.

Institute of Medical Informatics and Statistics, Christian-Albrechts University, Brunswiker Straße 10, 24105, Kiel, Germany.

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http://dx.doi.org/10.1007/s11357-013-9578-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039245PMC
April 2014

Polymorphisms in the superoxidase dismutase genes reveal no association with human longevity in Germans: a case-control association study.

Biogerontology 2013 Dec 22;14(6):719-27. Epub 2013 Oct 22.

Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Schittenhelmstraße 12, 24105, Kiel, Germany.

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http://link.springer.com/10.1007/s10522-013-9470-3
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http://dx.doi.org/10.1007/s10522-013-9470-3DOI Listing
December 2013

Genetic investigation of FOXO3A requires special attention due to sequence homology with FOXO3B.

Eur J Hum Genet 2013 Feb 16;21(2):240-2. Epub 2012 May 16.

Institute of Clinical Molecular Biology, Christian-Albrechts-University, Schittenhelmstrasse 12,Kiel, Germany.

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http://dx.doi.org/10.1038/ejhg.2012.83DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548564PMC
February 2013

Genome-wide miRNA signatures of human longevity.

Aging Cell 2012 Aug 30;11(4):607-16. Epub 2012 May 30.

Institute of Clinical Molecular Biology, Christian-Albrechts-University, Schittenhelmstraße 12, D-24105 Kiel, Germany.

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http://dx.doi.org/10.1111/j.1474-9726.2012.00824.xDOI Listing
August 2012

Genetic variation in the CYP2C monooxygenase enzyme subfamily shows no association with longevity in a German population.

J Gerontol A Biol Sci Med Sci 2011 Nov 27;66(11):1186-91. Epub 2011 Jul 27.

Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Schittenhelmstraße 12, 24105 Kiel, Germany.

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https://academic.oup.com/biomedgerontology/article-lookup/do
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http://dx.doi.org/10.1093/gerona/glr117DOI Listing
November 2011

Candidate gene study of FOXO1, FOXO4, and FOXO6 reveals no association with human longevity in Germans.

Aging Cell 2011 Aug 12;10(4):622-8. Epub 2011 Apr 12.

Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Schittenhelmstrasse 12, Kiel, Germany.

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http://dx.doi.org/10.1111/j.1474-9726.2011.00698.xDOI Listing
August 2011

Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.

Mutat Res 2010 Dec 26;694(1-2):13-9. Epub 2010 Aug 26.

Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, Germany.

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http://dx.doi.org/10.1016/j.mrfmmm.2010.08.006DOI Listing
December 2010

A functional haplotype in the 3'untranslated region of TNFRSF1B is associated with tuberculosis in two African populations.

Am J Respir Crit Care Med 2010 Feb 10;181(4):388-93. Epub 2009 Dec 10.

Molecular Biology and Human Genetics, MRC Centre for Molecular and Cellular Biology and DST/NRF Centre of Excellence for Biomedical TB Research, Stellenbosch University, Stellenbosch, South Africa.

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http://dx.doi.org/10.1164/rccm.200905-0678OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822974PMC
February 2010

Depletion of potential A2M risk haplotype for Alzheimer's disease in long-lived individuals.

Eur J Hum Genet 2010 Jan;18(1):59-61

Institute of Clinical Molecular Biology, Christian-Albrechts University and University Hospital Schleswig-Holstein, 24105 Kiel, Germany.

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http://dx.doi.org/10.1038/ejhg.2009.136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987169PMC
January 2010

Human longevity and 11p15.5: a study in 1321 centenarians.

Eur J Hum Genet 2009 Nov 15;17(11):1515-9. Epub 2009 Apr 15.

Centro Interdipartimentale 'L.Galvani' per Studi Integrati di Bioinformatica, Biofisica e Biocomplessità - Alma Mater Studiorum Università di Bologna, Italy.

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http://www.nature.com/articles/ejhg200954
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http://dx.doi.org/10.1038/ejhg.2009.54DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2986679PMC
November 2009

Association of FOXO3A variation with human longevity confirmed in German centenarians.

Proc Natl Acad Sci U S A 2009 Feb 5;106(8):2700-5. Epub 2009 Feb 5.

Institute of Clinical Molecular Biology, Institute of Medical Informatics and Statistics, and Popgen Biobank, Christian-Albrechts-University, 24105 Kiel, Germany.

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http://www.pnas.org/lookup/doi/10.1073/pnas.0809594106
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http://dx.doi.org/10.1073/pnas.0809594106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650329PMC
February 2009

Role of the toll-like receptor 4 polymorphism Asp299Gly in longevity and myocardial infarction in German men.

Mech Ageing Dev 2007 May-Jun;128(5-6):409-11. Epub 2007 Apr 7.

Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Germany.

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http://dx.doi.org/10.1016/j.mad.2007.04.001DOI Listing
September 2007

Sirtuin 1 (SIRT1) sequence variation is not associated with exceptional human longevity.

Exp Gerontol 2006 Jan 27;41(1):98-102. Epub 2005 Oct 27.

Institute for Clinical Molecular Biology, University Hospital Schleswig-Holstein, 24105 Kiel, Germany.

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http://dx.doi.org/10.1016/j.exger.2005.09.008DOI Listing
January 2006

[Genetic factors in longevity. Healthy living into old age--what role do genes play?].

Med Monatsschr Pharm 2005 Dec;28(12):437-42

Institut für Klinische Molekularbiologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel.

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December 2005