Friedemann Honecker

Friedemann Honecker

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Friedemann Honecker

Publications by authors named "Friedemann Honecker"

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Proteomic Comparison of Malignant Human Germ Cell Tumor Cell Lines.

Dis Markers 2019 3;2019:8298524. Epub 2019 Sep 3.

Department of Oncology, Hematology and Bone Marrow Transplantation with Section of Pneumology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1155/2019/8298524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745167PMC
September 2019

Everolimus in patients with multiply relapsed or cisplatin refractory germ cell tumors: results of a phase II, single-arm, open-label multicenter trial (RADIT) of the German Testicular Cancer Study Group.

J Cancer Res Clin Oncol 2019 Mar 19;145(3):717-723. Epub 2018 Sep 19.

Department of Oncology, Hematology and Bone Marrow Transplantation and Section of Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1007/s00432-018-2752-zDOI Listing
March 2019

Palliative treatment of germ cell cancer.

Cancer Treat Rev 2018 Dec 22;71:102-107. Epub 2018 Oct 22.

Department of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse, CH-3031 Bern, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03057372183016
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http://dx.doi.org/10.1016/j.ctrv.2018.10.007DOI Listing
December 2018

5-Azacitidine Exerts Prolonged Pro-Apoptotic Effects and Overcomes Cisplatin-Resistance in Non-Seminomatous Germ Cell Tumor Cells.

Int J Mol Sci 2018 Dec 21;20(1). Epub 2018 Dec 21.

Department of Oncology, Hematology and Bone Marrow Transplantation with Division of Pneumology, University Medical Center Eppendorf, 20246 Hamburg, Germany.

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http://dx.doi.org/10.3390/ijms20010021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337423PMC
December 2018

Marine Compounds and Autophagy: Beginning of a New Era.

Mar Drugs 2018 Jul 31;16(8). Epub 2018 Jul 31.

Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald-Tumorzentrum, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

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http://dx.doi.org/10.3390/md16080260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117714PMC
July 2018

Risk factors for unplanned discontinuation of scheduled treatment in elderly patients with castration-resistant prostate cancer: results of the IBuTu study.

J Cancer Res Clin Oncol 2018 Mar 4;144(3):571-577. Epub 2018 Jan 4.

Gesundheitsforschung für Männer gGmbH, Claire-Waldoff-Str. 3, 10117, Berlin, Germany.

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http://dx.doi.org/10.1007/s00432-017-2577-1DOI Listing
March 2018

Structure-activity Relationship Studies of New Marine Anticancer Agents and their Synthetic Analogues.

Curr Med Chem 2017 ;24(42):4779-4799

Laboratory of Marine Natural Products Chemistry, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-East Branch, Russian Academy of Sciences, Prospect 100-let Vladivostoku 159, Vladivostok 690022, Russian Federation.

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http://dx.doi.org/10.2174/0929867324666161121115404DOI Listing
February 2018

Marine Compounds and Cancer: 2017 Updates.

Mar Drugs 2018 Jan 24;16(2). Epub 2018 Jan 24.

Laboratory of Experimental Oncology, Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald-Tumorzentrum, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

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http://dx.doi.org/10.3390/md16020041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852469PMC
January 2018

Frondoside A induces AIF-associated caspase-independent apoptosis in Burkitt lymphoma cells.

Leuk Lymphoma 2017 12 16;58(12):2905-2915. Epub 2017 May 16.

a Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology , Hubertus Wald-Tumorzentrum, University Medical Center Hamburg-Eppendorf , Hamburg , Germany.

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http://dx.doi.org/10.1080/10428194.2017.1317091DOI Listing
December 2017

Proteomic-based investigations on the mode of action of the marine anticancer compound rhizochalinin.

Proteomics 2017 Jun;17(11)

Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald-Tumorzentrum, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1002/pmic.201700048DOI Listing
June 2017

The marine triterpene glycoside frondoside A induces p53-independent apoptosis and inhibits autophagy in urothelial carcinoma cells.

BMC Cancer 2017 02 1;17(1):93. Epub 2017 Feb 1.

Laboratory of Experimental Oncology, Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg, 20246, Germany.

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http://dx.doi.org/10.1186/s12885-017-3085-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286817PMC
February 2017

Evaluation of geriatric assessment in patients with chronic lymphocytic leukemia: Results of the CLL9 trial of the German CLL study group.

Leuk Lymphoma 2016 13;57(4):789-96. Epub 2015 Oct 13.

a German CLL Study Group, Department I of Internal Medicine , Center of Integrated Oncology Cologne-Bonn, University Hospital Cologne , Cologne , Germany .

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http://www.tandfonline.com/doi/full/10.3109/10428194.2015.10
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http://dx.doi.org/10.3109/10428194.2015.1091933DOI Listing
December 2016

Cabazitaxel overcomes cisplatin resistance in germ cell tumour cells.

J Cancer Res Clin Oncol 2016 Sep 16;142(9):1979-94. Epub 2016 Jul 16.

Department of Oncology, Hematology and Bone Marrow Transplantation, University Medical Center Hamburg-Eppendorf, Martinistaße 52, 20246, Hamburg, Germany.

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http://dx.doi.org/10.1007/s00432-016-2204-6DOI Listing
September 2016

Guanidine Alkaloids from the Marine Sponge Monanchora pulchra Show Cytotoxic Properties and Prevent EGF-Induced Neoplastic Transformation in Vitro.

Mar Drugs 2016 Jul 15;14(7). Epub 2016 Jul 15.

Laboratory of Experimental Oncology, Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald-Tumorzentrum, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, Hamburg 20246, Germany.

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http://dx.doi.org/10.3390/md14070133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962023PMC
July 2016

Anti-migratory activity of marine alkaloid monanchocidin A - proteomics-based discovery and confirmation.

Proteomics 2016 05 27;16(10):1590-603. Epub 2016 Apr 27.

Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald-Tumorzentrum, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1002/pmic.201500334DOI Listing
May 2016

Activity of nintedanib in germ cell tumors.

Anticancer Drugs 2016 Feb;27(2):89-98

aLaboratory of Experimental Oncology, Department of Oncology, Hematology, Bone Marrow Transplantation with Section Pneumology, Hubertus Wald Tumor Center, University Hospital Hamburg-Eppendorf, Hamburg bInstitute of Physiology, Charité, Universitätsmedizin Berlin, Berlin, Germany cTumor and Breast Center ZeTuP, St. Gallen, Switzerland.

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http://dx.doi.org/10.1097/CAD.0000000000000305DOI Listing
February 2016

Emerging Therapeutic Targets for Male Germ Cell Tumors.

Curr Oncol Rep 2015 Dec;17(12):54

Institute of Surgical Pathology, University Hospital Zurich, Schmelzbergstrasse 12, Zurich, 8091, Switzerland.

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http://dx.doi.org/10.1007/s11912-015-0479-4DOI Listing
December 2015

Regulation of tissue factor in NT2 germ cell tumor cells by cisplatin chemotherapy.

Thromb Res 2015 Sep 14;136(3):673-81. Epub 2015 Jul 14.

II. Medizinische Klinik und Poliklinik, Onkologisches Zentrum - Universitäres Cancer Center Hamburg (UCCH), Universitätsklinikum Eppendorf, Martinistr. 52, D-20246 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2015.07.002DOI Listing
September 2015

Marine Compounds and Cancer: Where Do We Stand?

Mar Drugs 2015 Sep 2;13(9):5657-65. Epub 2015 Sep 2.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584346PMC
September 2015

First salvage treatment of germ cell tumor patients with bone metastases: retrospective analysis of a large international database.

J Cancer Res Clin Oncol 2015 May 14;141(5):923-31. Epub 2014 Nov 14.

Department of Oncology, Hematology and Bone Marrow Transplantation, University Medical Center Eppendorf, Martinistr. 52, 20246, Hamburg, Germany,

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http://dx.doi.org/10.1007/s00432-014-1876-zDOI Listing
May 2015

Aaptamines from the marine sponge Aaptos sp. display anticancer activities in human cancer cell lines and modulate AP-1-, NF-κB-, and p53-dependent transcriptional activity in mouse JB6 Cl41 cells.

Biomed Res Int 2014 23;2014:469309. Epub 2014 Jul 23.

Department of Oncology, Haematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald-Tumorzentrum, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany ; Tumor and Breast Center ZeTuP St. Gallen, Rorschacherstraße 150, 9006 St. Gallen, Switzerland.

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http://dx.doi.org/10.1155/2014/469309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158141PMC
April 2015

Nodal, pulmonary and pleural gliomatosis in a 42-year-old-male with non-seminomatous testicular germ cell cancer.

Histopathology 2014 Jul 14;65(1):142-3. Epub 2014 Mar 14.

Department of Oncology, Hematology and Bone Marrow Transplantation, University Medical Center Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1111/his.12374DOI Listing
July 2014

First salvage treatment in patients with advanced germ cell cancer after cisplatin-based chemotherapy: analysis of a registry of the German Testicular Cancer Study Group (GTCSG).

J Cancer Res Clin Oncol 2014 Jul 3;140(7):1211-20. Epub 2014 Apr 3.

Department of Oncology, Hematology, BMT with Section of Pneumology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany,

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http://dx.doi.org/10.1007/s00432-014-1661-zDOI Listing
July 2014

Venous thromboembolic events in germ cell cancer patients undergoing platinum-based chemotherapy.

Onkologie 2013 14;36(11):663-8. Epub 2013 Oct 14.

Department of Oncology, Hematology and Bone Marrow Transplantation with Section of Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1159/000355652DOI Listing
June 2014

Quinone-carbohydrate nonglucoside conjugates as a new type of cytotoxic agents: synthesis and determination of in vitro activity.

Eur J Med Chem 2014 Apr 5;77:139-44. Epub 2014 Mar 5.

G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Russian Academy of Sciences, 690022 Vladivostok, Prospect 100 let Vladivostoku 159, Russia. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2014.03.006DOI Listing
April 2014

Late recurrence of a pineal germinoma 14 years after radiation and chemotherapy: a case report and review of the literature.

Onkologie 2013 21;36(6):371-3. Epub 2013 May 21.

Department of Oncology and Hematology, Hubertus Wald Tumor Center - University Cancer Center Hamburg, Germany.

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http://dx.doi.org/10.1159/000351255DOI Listing
January 2014

Activity of aaptamine and two derivatives, demethyloxyaaptamine and isoaaptamine, in cisplatin-resistant germ cell cancer.

J Proteomics 2014 Jan 21;96:223-39. Epub 2013 Nov 21.

Department of Oncology, Haematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald-Tumorzentrum, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2013.11.009DOI Listing
January 2014

Proteome analysis of the effects of all-trans retinoic acid on human germ cell tumor cell lines.

J Proteomics 2014 Jan 22;96:300-13. Epub 2013 Nov 22.

Department of Oncology, Hematology and Bone Marrow Transplantation with section Pneumology, Hubertus Wald-Tumor Zentrum (UCCH), University Hospital Eppendorf (UKE), Hamburg, Germany; Division of Hematology, University Hospital Zürich, Zürich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2013.11.010DOI Listing
January 2014

Bone metastases in germ cell tumor patients.

J Cancer Res Clin Oncol 2012 Jun 21;138(6):947-52. Epub 2012 Feb 21.

Department of Oncology/Hematology/Bone marrow transplantation/Pneumology, University Medical Center Eppendorf, Martinistr 52, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1007/s00432-012-1169-3DOI Listing
June 2012

Mycalamide A shows cytotoxic properties and prevents EGF-induced neoplastic transformation through inhibition of nuclear factors.

Mar Drugs 2012 Jun 30;10(6):1212-24. Epub 2012 May 30.

Laboratory of Marine Natural Products Chemistry, GB Elyakov Pacific Institute of Bioorganic Chemistry, Far-East Branch of the Russian Academy of Sciences, Prospect 100-let Vladivostoku 159, Vladivostok 690022, Russia.

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http://dx.doi.org/10.3390/md10061212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397435PMC
June 2012

Proteomic profiling of germ cell cancer cells treated with aaptamine, a marine alkaloid with antiproliferative activity.

J Proteome Res 2012 Apr 28;11(4):2316-30. Epub 2012 Mar 28.

Department of Oncology, Haematology and Bone Marrow Transplantation, Section Pneumology, Hubertus Wald-Tumorzentrum, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1021/pr300170pDOI Listing
April 2012

Micro-RNA expression in cisplatin resistant germ cell tumor cell lines.

Mol Cancer 2011 May 15;10:52. Epub 2011 May 15.

Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1186/1476-4598-10-52DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120796PMC
May 2011

Multi tyrosine kinase inhibitor dasatinib as novel cause of severe pre-capillary pulmonary hypertension?

BMC Pulm Med 2011 May 23;11:30. Epub 2011 May 23.

Centre for Pulmonary Hypertension, University Medical Centre Hamburg - Eppendorf, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1186/1471-2466-11-30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121732PMC
May 2011

Histopathological and molecular features of late relapses in non-seminomas.

BJU Int 2011 Mar 18;107(6):936-43. Epub 2010 Oct 18.

Department of Oncology, Haematology, Immunology, Rheumathology and Pulmology, University of Tübingen Medical Centre, Tübingen, Germany.

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http://dx.doi.org/10.1111/j.1464-410X.2010.09631.xDOI Listing
March 2011

Global DNA methylation in fetal human germ cells and germ cell tumours: association with differentiation and cisplatin resistance.

J Pathol 2010 Aug;221(4):433-42

Department of Pathology, Erasmus MC-Erasmus University Medical Center, Daniel den Hoed Cancer Center, Josephine Nefkens Institute, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/path.2725DOI Listing
August 2010

Patterns of relapse after chemotherapy in patients with high-risk non-seminomatous germ cell tumor.

Oncology 2010 6;78(1):47-53. Epub 2010 Mar 6.

Department of Oncology/Hematology/Bone Marrow Transplantation/Pneumology, University Cancer Center Hamburg-Eppendorf, Martinistrasse 52, DE-20246 Hamburg, Germany.

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http://dx.doi.org/10.1159/000292358DOI Listing
April 2010

Lenalidomide in patients with cisplatin-refractory and multiply relapsed germ cell tumors.

J Cancer Res Clin Oncol 2010 Jan 16;136(1):165-7. Epub 2009 Sep 16.

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http://dx.doi.org/10.1007/s00432-009-0677-2DOI Listing
January 2010

[Registries and clinical trials in geriatric oncology in Germany].

Onkologie 2009 25;32 Suppl 3:14-8. Epub 2009 Sep 25.

II Medizinische Klinik und Poliklinik, Onkologie, Hämatologie und Knochenmarktransplantation mit Sektion Pneumologie, Universitätsklinikum Hamburg-Eppendorf, Deutschland.

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http://dx.doi.org/10.1159/000228649DOI Listing
January 2010

Molecular determinants of response to matuzumab in combination with paclitaxel for patients with advanced non-small cell lung cancer.

Mol Cancer Ther 2009 Mar 10;8(3):481-9. Epub 2009 Mar 10.

University Hospital Tübingen, Department of Hematology, Oncology, Rheumatology, Immunology and Pulmonology, Otfried-Müller-Strasse 10, 72074 Tübingen, Germany.

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http://dx.doi.org/10.1158/1535-7163.MCT-08-1068DOI Listing
March 2009

Comparative proteome, transcriptome, and genome analysis of a gonadal and an extragonadal germ cell tumor cell line.

J Proteome Res 2008 Sep 22;7(9):3890-9. Epub 2008 Jul 22.

Department of Oncology/Hematology/Bone Marrow Transplantation with the section of Pneumology, University Hospital Hamburg Eppendorf, Germany.

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http://pubs.acs.org/doi/abs/10.1021/pr800173g
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http://dx.doi.org/10.1021/pr800173gDOI Listing
September 2008

Why human extragonadal germ cell tumours occur in the midline of the body: old concepts, new perspectives.

Int J Androl 2007 Aug;30(4):256-63; discussion 263-4

Department of Pathology, Erasmus University Medical Center, Josephine Nefkens Institute, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/j.1365-2605.2007.00793.xDOI Listing
August 2007

Vitamin D in the treatment of pulmonary tuberculosis.

J Steroid Biochem Mol Biol 2007 Mar 12;103(3-5):793-8. Epub 2007 Jan 12.

Centre for Health Sciences, Institute of Health Sciences Education, Barts and The London School of Medicine and Dentistry, London E1 2AT, United Kingdom.

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http://dx.doi.org/10.1016/j.jsbmb.2006.12.052DOI Listing
March 2007

Tolerance to chemotherapy in elderly patients with cancer.

Cancer Control 2007 Jan;14(1):44-56

Klinik und Poliklinik fur Innere Medizin II, Department of Hematology and Oncology, Friedrich Schiller Universitat, Erlanger Allee 101, D-07747 Jena, Germany.

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http://dx.doi.org/10.1177/107327480701400106DOI Listing
January 2007

Normal and malignant germ cell development.

Crit Rev Oncog 2006 Dec;12(3-4):297-8; discussion 298-9

Department of Oncology and Hematology, Laboratory of Experimental Oncology, University Hospital Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg, Germany.

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December 2006

Cell-cycle progression and response of germ cell tumors to cisplatin in vitro.

Int J Oncol 2006 Aug;29(2):471-9

Department of Oncology, Hematology, Immunology and Rheumatology, Medical Center, University of Tuebingen, Germany.

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August 2006

Safe use of oxaliplatin in a patient with metastatic breast cancer and combined renal and hepatic failure.

Onkologie 2006 Jun;29(6):273-5

Zentrum für Innere Medizin, Medizinische Klinik und Poliklkinik, Universitätsklinikum Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1159/000093032DOI Listing
June 2006

Germ cell lineage differentiation in non-seminomatous germ cell tumours.

J Pathol 2006 Feb;208(3):395-400

Department of Pathology, Erasmus MC-University Medical Center Rotterdam, Daniel den Hoed Cancer Center, Josephine Nefkens Institute, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/path.1872DOI Listing
February 2006

Maturation delay of germ cells in fetuses with trisomy 21 results in increased risk for the development of testicular germ cell tumors.

Hum Pathol 2006 Jan;37(1):101-11

Department of Pathology, Josephine Nefkens Institute, Erasmus MC-University Medical Center, Daniel den Hoed, 3000 DR Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.humpath.2005.09.021DOI Listing
January 2006

Identification of germ cells at risk for neoplastic transformation in gonadoblastoma: an immunohistochemical study for OCT3/4 and TSPY.

Hum Pathol 2005 May;36(5):512-21

Department of Pathology, Josephine Nefkens Institute, Daniel de Hoed Cancer Center, Erasmus MC-University Medical Center Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.humpath.2005.02.016DOI Listing
May 2005

Pathobiological implications of the expression of markers of testicular carcinoma in situ by fetal germ cells.

J Pathol 2004 Jul;203(3):849-57

Department of Pathology, Josephine Nefkens Institute, Erasmus MC-University Medical Center Rotterdam, Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/path.1587DOI Listing
July 2004

New insights into the pathology and molecular biology of human germ cell tumors.

World J Urol 2004 Apr 20;22(1):15-24. Epub 2004 Mar 20.

Department of Pathology, Josephine Nefkens Institute, Erasmus MC-University Medical Center Rotterdam, Daniel den Hoed Cancer Center, Room 430b, P.O. Box 1738 3000 DR Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00345-004-0399-7DOI Listing
April 2004

Xeroderma pigmentosum group a protein and chemotherapy resistance in human germ cell tumors.

Lab Invest 2003 Oct;83(10):1489-95

Department of Pathology, Laboratory for Experimental Patho-Oncology, Josephine Nefkens Institute, Erasmus MC, University Medical Center Rotterdam, Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.

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October 2003

Colorectal cancer in the elderly: is palliative chemotherapy of value?

Drugs Aging 2003 ;20(1):1-11

Department of Hematology/Oncology/Immunology, University Medical Center II, Eberhard-Karls-Universität, Tübingen, Federal Republic of Germany.

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http://link.springer.com/10.2165/00002512-200320010-00001
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http://dx.doi.org/10.2165/00002512-200320010-00001DOI Listing
June 2003