Freya Shephard

Freya Shephard

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Freya Shephard

Freya Shephard

Publications by authors named "Freya Shephard"

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18Publications

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A comparison of the mitochondrial proteome and lipidome in the mouse and long-lived Pipistrelle bats.

Aging (Albany NY) 2019 03;11(6):1664-1685

School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, LE12 5RD, UK.

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http://dx.doi.org/10.18632/aging.101861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461166PMC
March 2019

Elevated 5hmC levels characterize DNA of the cerebellum in Parkinson's disease.

NPJ Parkinsons Dis 2017 1;3. Epub 2017 Feb 1.

School of Veterinary Medicine and Science, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, LE12 5RD UK.

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http://dx.doi.org/10.1038/s41531-017-0007-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460211PMC
February 2017

Mitochondrial proteomic profiling reveals increased carbonic anhydrase II in aging and neurodegeneration.

Aging (Albany NY) 2016 10;8(10):2425-2436

School of Biosciences, University of Nottingham, Sutton Bonington, LE12 5RD, UK.

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http://dx.doi.org/10.18632/aging.101064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115898PMC
October 2016

Analysis of Mitochondrial haemoglobin in Parkinson's disease brain.

Mitochondrion 2016 07 12;29:45-52. Epub 2016 May 12.

University of Nottingham, Faculty of Medicine, SVMS, Sutton Bonington Campus, LE12 5RD, England, UK. Electronic address:

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http://dx.doi.org/10.1016/j.mito.2016.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940210PMC
July 2016

Degenerin channel activation causes caspase-mediated protein degradation and mitochondrial dysfunction in adult C. elegans muscle.

J Cachexia Sarcopenia Muscle 2016 05 4;7(2):181-92. Epub 2015 Jun 4.

MRC/ARUK Centre for Musculoskeletal Ageing Research, Faculty of Medicine and Health Sciences University of Nottingham Nottingham NG7 2UH UK.

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http://dx.doi.org/10.1002/jcsm.12040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864282PMC
May 2016

The integrin-adhesome is required to maintain muscle structure, mitochondrial ATP production, and movement forces in Caenorhabditis elegans.

FASEB J 2015 Apr 9;29(4):1235-46. Epub 2014 Dec 9.

*Department of Sport and Health Science, College of Life and Environmental Sciences, and College of Engineering, Mathematics and Physical Science, University of Exeter, Exeter, United Kingdom; Departments of Chemical Engineering and Mechanical Engineering, Texas Tech University, Lubbock, Texas, USA; Medical Research Council/Arthritis Research UK Centre for Musculoskeletal Ageing Research, Schools of Life Sciences and Medicine, University of Nottingham, Nottingham, United Kingdom; and School of Veterinary Medicine and Science, University of Nottingham, Leicestershire, United Kingdom.

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http://dx.doi.org/10.1096/fj.14-259119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396603PMC
April 2015

Using Multiple Phenotype Assays and Epistasis Testing to Enhance the Reliability of RNAi Screening and Identify Regulators of Muscle Protein Degradation.

Genes (Basel) 2012 2;3(4):686-701. Epub 2012 Nov 2.

Medical Resarch Council/Arthritis Research UK Centre for Musculoskeletal Ageing Research, University of Nottingham, Royal Derby Hospital, Derby, DE22 3DT, UK.

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http://dx.doi.org/10.3390/genes3040686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495584PMC
April 2014

Protective role of DNJ-27/ERdj5 in Caenorhabditis elegans models of human neurodegenerative diseases.

Antioxid Redox Signal 2014 Jan 3;20(2):217-35. Epub 2013 Jul 3.

1 Centro Andaluz de Biología del Desarrollo (CABD-CSIC), Depto. de Fisiología, Anatomía y Biología Celular, Universidad Pablo de Olavide , Sevilla, Spain .

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http://dx.doi.org/10.1089/ars.2012.5051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887457PMC
January 2014

A mitochondrial location for haemoglobins--dynamic distribution in ageing and Parkinson's disease.

Mitochondrion 2014 Jan 10;14(1):64-72. Epub 2013 Dec 10.

School of Veterinary Medicine and Science, Faculty of Medicine and Health Sciences, University of Nottingham, LE12 5RD, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.mito.2013.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969298PMC
January 2014

A single residue change leads to a hydroxylated product from the class II diterpene cyclization catalyzed by abietadiene synthase.

Org Lett 2012 Dec 20;14(23):5828-31. Epub 2012 Nov 20.

Department of Biochemistry, Biophysics, & Molecular Biology, Iowa State University, Ames, Iowa 50011, USA.

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http://dx.doi.org/10.1021/ol3026022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518578PMC
December 2012

Integrated control of protein degradation in C. elegans muscle.

Worm 2012 Jul;1(3):141-50

Medical Research Council/Arthritis Research UK Centre for Musculoskeletal Ageing Research; University of Nottingham; Royal Derby Hospital; Derby, UK.

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http://dx.doi.org/10.4161/worm.20465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583358PMC
July 2012

Identification and functional clustering of genes regulating muscle protein degradation from amongst the known C. elegans muscle mutants.

PLoS One 2011 27;6(9):e24686. Epub 2011 Sep 27.

School of Graduate Entry Medicine and Health, University of Nottingham, Royal Derby Hospital, Derby, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0024686PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181249PMC
April 2012

Distinct control of MyD88 adapter-dependent and Akt kinase-regulated responses by the interleukin (IL)-1RI co-receptor, TILRR.

J Biol Chem 2012 Apr 19;287(15):12348-52. Epub 2012 Jan 19.

Cell Biology Group, University of Sheffield, Sheffield S10 2RX, United Kingdom.

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http://dx.doi.org/10.1074/jbc.C111.321711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320984PMC
April 2012

Calpains mediate integrin attachment complex maintenance of adult muscle in Caenorhabditis elegans.

PLoS Genet 2012 Jan 12;8(1):e1002471. Epub 2012 Jan 12.

School of Graduate Entry Medicine and Health, University of Nottingham, Royal Derby Hospital, Derby, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1002471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257289PMC
January 2012

Identification of mutants of Arabidopsis defective in acclimation of photosynthesis to the light environment.

Plant Physiol 2003 Feb;131(2):472-81

Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield S10 2TN, United Kingdom.

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http://dx.doi.org/10.1104/pp.015479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC166824PMC
February 2003