Fredrik Nyberg

Fredrik Nyberg

UNVERIFIED PROFILE

Are you Fredrik Nyberg?   Register this Author

Register author
Fredrik Nyberg

Fredrik Nyberg

Publications by authors named "Fredrik Nyberg"

Are you Fredrik Nyberg?   Register this Author

80Publications

2587Reads

44Profile Views

Group IIA Secretory Phospholipase A, Vascular Inflammation, and Incident Cardiovascular Disease.

Arterioscler Thromb Vasc Biol 2019 Jun;39(6):1182-1190

From the Center for Lipid Metabolomics, Division of Preventive Medicine (A.O.A., P.R.L., R.J.G., P.M.R., D.I.C., S.M.), Department of Medicine, Brigham and Women's Hospital, Boston, MA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.118.311894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534275PMC
June 2019

Gefitinib exposure and occurrence of interstitial lung disease in Japanese patients with non-small-cell lung cancer.

Cancer Chemother Pharmacol 2019 May 14;83(5):849-858. Epub 2019 Feb 14.

Department of Clinical Pharmacokinetics and Pharmacodynamics, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00280-019-03788-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458983PMC
May 2019

Cohort Profile: The INTERGENE Study.

Int J Epidemiol 2017 12;46(6):1742-1743h

Section for Epidemiology and Social Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ije/dyw332DOI Listing
December 2017

Patient perspectives on neuromyelitis optica spectrum disorders: Data from the PatientsLikeMe online community.

Mult Scler Relat Disord 2017 Oct 11;17:116-122. Epub 2017 Jul 11.

PatientsLikeMe Inc., 160 s Street, Cambridge, MA 02142, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.msard.2017.07.014DOI Listing
October 2017

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins.

J Med Genet 2016 12 1;53(12):835-845. Epub 2016 Sep 1.

Department of Atherosclerosis Research, Children's Hospital Oakland Research Institute, Oakland, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jmedgenet-2016-103966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309131PMC
December 2016

How comparable are rates of malignancies in patients with rheumatoid arthritis across the world? A comparison of cancer rates, and means to optimise their comparability, in five RA registries.

Ann Rheum Dis 2016 Oct 30;75(10):1789-96. Epub 2015 Nov 30.

Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, UK NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/annrheumdis-2015-208105DOI Listing
October 2016

FTO gene variation, macronutrient intake and coronary heart disease risk: a gene-diet interaction analysis.

Eur J Nutr 2016 Feb 3;55(1):247-55. Epub 2015 Feb 3.

Occupational and Environmental Medicine Unit, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Box 414, 405 30, Gothenburg, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00394-015-0842-0DOI Listing
February 2016

Progressive multifocal leukoencephalopathy: current treatment options and future perspectives.

Ther Adv Neurol Disord 2015 Nov;8(6):255-73

The Progressive Multifocal Leukeoncephalopathy Consortium Secretariat, Drinker Biddle & Reath LLP, 1500 K Street NW, Washington, DC, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1756285615602832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643867PMC
November 2015

Differential Genetic Effects on Statin-Induced Changes Across Low-Density Lipoprotein-Related Measures.

Circ Cardiovasc Genet 2015 Oct 13;8(5):688-95. Epub 2015 Aug 13.

From the Division of Preventive Medicine (A.Y.C., F.G., S.M., P.M.R., D.I.C.), Division of Cardiovascular Medicine (S.M., P.M.R.), Division of Genetics (D.I.C.), Brigham and Women's Hospital and Harvard Medical School, Boston, MA; Personalised Healthcare and Biomarkers AstraZeneca Research and Development, Alderley Park, United Kingdom (B.J.B.); Observational Research Center, AstraZeneca Research and Development, Mölndal (B.D., F.N.); and Unit of Occupational and Environmental Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden (F.N.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCGENETICS.114.000962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618030PMC
October 2015

Exposure to traffic and lung function in adults: a general population cohort study.

BMJ Open 2015 Jun 24;5(6):e007624. Epub 2015 Jun 24.

Section of Occupational and Environmental Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmjopen-2015-007624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479998PMC
June 2015

Interaction effects of long-term air pollution exposure and variants in the GSTP1, GSTT1 and GSTCD genes on risk of acute myocardial infarction and hypertension: a case-control study.

PLoS One 2014 10;9(6):e99043. Epub 2014 Jun 10.

Occupational and Environmental Medicine, Department of Public Health & Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; AstraZeneca R&D, Mölndal, Sweden.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0099043PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4051658PMC
January 2015

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.

Authors:
Iris Postmus Stella Trompet Harshal A Deshmukh Michael R Barnes Xiaohui Li Helen R Warren Daniel I Chasman Kaixin Zhou Benoit J Arsenault Louise A Donnelly Kerri L Wiggins Christy L Avery Paula Griffin QiPing Feng Kent D Taylor Guo Li Daniel S Evans Albert V Smith Catherine E de Keyser Andrew D Johnson Anton J M de Craen David J Stott Brendan M Buckley Ian Ford Rudi G J Westendorp P Eline Slagboom Naveed Sattar Patricia B Munroe Peter Sever Neil Poulter Alice Stanton Denis C Shields Eoin O'Brien Sue Shaw-Hawkins Y-D Ida Chen Deborah A Nickerson Joshua D Smith Marie Pierre Dubé S Matthijs Boekholdt G Kees Hovingh John J P Kastelein Paul M McKeigue John Betteridge Andrew Neil Paul N Durrington Alex Doney Fiona Carr Andrew Morris Mark I McCarthy Leif Groop Emma Ahlqvist Joshua C Bis Kenneth Rice Nicholas L Smith Thomas Lumley Eric A Whitsel Til Stürmer Eric Boerwinkle Julius S Ngwa Christopher J O'Donnell Ramachandran S Vasan Wei-Qi Wei Russell A Wilke Ching-Ti Liu Fangui Sun Xiuqing Guo Susan R Heckbert Wendy Post Nona Sotoodehnia Alice M Arnold Jeanette M Stafford Jingzhong Ding David M Herrington Stephen B Kritchevsky Gudny Eiriksdottir Leonore J Launer Tamara B Harris Audrey Y Chu Franco Giulianini Jean G MacFadyen Bryan J Barratt Fredrik Nyberg Bruno H Stricker André G Uitterlinden Albert Hofman Fernando Rivadeneira Valur Emilsson Oscar H Franco Paul M Ridker Vilmundur Gudnason Yongmei Liu Joshua C Denny Christie M Ballantyne Jerome I Rotter L Adrienne Cupples Bruce M Psaty Colin N A Palmer Jean-Claude Tardif Helen M Colhoun Graham Hitman Ronald M Krauss J Wouter Jukema Mark J Caulfield

Nat Commun 2014 Oct 28;5:5068. Epub 2014 Oct 28.

1] NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London EC1M 6BQ, UK [2] Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, London EC1M6BQ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms6068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220464PMC
October 2014

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

Authors:
Dan E Arking Sara L Pulit Lia Crotti Pim van der Harst Patricia B Munroe Tamara T Koopmann Nona Sotoodehnia Elizabeth J Rossin Michael Morley Xinchen Wang Andrew D Johnson Alicia Lundby Daníel F Gudbjartsson Peter A Noseworthy Mark Eijgelsheim Yuki Bradford Kirill V Tarasov Marcus Dörr Martina Müller-Nurasyid Annukka M Lahtinen Ilja M Nolte Albert Vernon Smith Joshua C Bis Aaron Isaacs Stephen J Newhouse Daniel S Evans Wendy S Post Daryl Waggott Leo-Pekka Lyytikäinen Andrew A Hicks Lewin Eisele David Ellinghaus Caroline Hayward Pau Navarro Sheila Ulivi Toshiko Tanaka David J Tester Stéphanie Chatel Stefan Gustafsson Meena Kumari Richard W Morris Åsa T Naluai Sandosh Padmanabhan Alexander Kluttig Bernhard Strohmer Andrie G Panayiotou Maria Torres Michael Knoflach Jaroslav A Hubacek Kamil Slowikowski Soumya Raychaudhuri Runjun D Kumar Tamara B Harris Lenore J Launer Alan R Shuldiner Alvaro Alonso Joel S Bader Georg Ehret Hailiang Huang W H Linda Kao James B Strait Peter W Macfarlane Morris Brown Mark J Caulfield Nilesh J Samani Florian Kronenberg Johann Willeit J Gustav Smith Karin H Greiser Henriette Meyer Zu Schwabedissen Karl Werdan Massimo Carella Leopoldo Zelante Susan R Heckbert Bruce M Psaty Jerome I Rotter Ivana Kolcic Ozren Polašek Alan F Wright Maura Griffin Mark J Daly David O Arnar Hilma Hólm Unnur Thorsteinsdottir Joshua C Denny Dan M Roden Rebecca L Zuvich Valur Emilsson Andrew S Plump Martin G Larson Christopher J O'Donnell Xiaoyan Yin Marco Bobbo Adamo P D'Adamo Annamaria Iorio Gianfranco Sinagra Angel Carracedo Steven R Cummings Michael A Nalls Antti Jula Kimmo K Kontula Annukka Marjamaa Lasse Oikarinen Markus Perola Kimmo Porthan Raimund Erbel Per Hoffmann Karl-Heinz Jöckel Hagen Kälsch Markus M Nöthen Marcel den Hoed Ruth J F Loos Dag S Thelle Christian Gieger Thomas Meitinger Siegfried Perz Annette Peters Hanna Prucha Moritz F Sinner Melanie Waldenberger Rudolf A de Boer Lude Franke Pieter A van der Vleuten Britt Maria Beckmann Eimo Martens Abdennasser Bardai Nynke Hofman Arthur A M Wilde Elijah R Behr Chrysoula Dalageorgou John R Giudicessi Argelia Medeiros-Domingo Julien Barc Florence Kyndt Vincent Probst Alice Ghidoni Roberto Insolia Robert M Hamilton Stephen W Scherer Jeffrey Brandimarto Kenneth Margulies Christine E Moravec Fabiola del Greco M Christian Fuchsberger Jeffrey R O'Connell Wai K Lee Graham C M Watt Harry Campbell Sarah H Wild Nour E El Mokhtari Norbert Frey Folkert W Asselbergs Irene Mateo Leach Gerjan Navis Maarten P van den Berg Dirk J van Veldhuisen Manolis Kellis Bouwe P Krijthe Oscar H Franco Albert Hofman Jan A Kors André G Uitterlinden Jacqueline C M Witteman Lyudmyla Kedenko Claudia Lamina Ben A Oostra Gonçalo R Abecasis Edward G Lakatta Antonella Mulas Marco Orrú David Schlessinger Manuela Uda Marcello R P Markus Uwe Völker Harold Snieder Timothy D Spector Johan Ärnlöv Lars Lind Johan Sundström Ann-Christine Syvänen Mika Kivimaki Mika Kähönen Nina Mononen Olli T Raitakari Jorma S Viikari Vera Adamkova Stefan Kiechl Maria Brion Andrew N Nicolaides Bernhard Paulweber Johannes Haerting Anna F Dominiczak Fredrik Nyberg Peter H Whincup Aroon D Hingorani Jean-Jacques Schott Connie R Bezzina Erik Ingelsson Luigi Ferrucci Paolo Gasparini James F Wilson Igor Rudan Andre Franke Thomas W Mühleisen Peter P Pramstaller Terho J Lehtimäki Andrew D Paterson Afshin Parsa Yongmei Liu Cornelia M van Duijn David S Siscovick Vilmundur Gudnason Yalda Jamshidi Veikko Salomaa Stephan B Felix Serena Sanna Marylyn D Ritchie Bruno H Stricker Kari Stefansson Laurie A Boyer Thomas P Cappola Jesper V Olsen Kasper Lage Peter J Schwartz Stefan Kääb Aravinda Chakravarti Michael J Ackerman Arne Pfeufer Paul I W de Bakker Christopher Newton-Cheh

Nat Genet 2014 Aug 22;46(8):826-36. Epub 2014 Jun 22.

1] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [3] Harvard Medical School, Boston, Massachusetts, USA. [4] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [5].

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124521PMC
August 2014

Haplotypes of the inducible nitric oxide synthase gene are strongly associated with exhaled nitric oxide levels in adults: a population-based study.

J Med Genet 2014 Jul 11;51(7):449-54. Epub 2014 Apr 11.

Occupational and Environmental Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden AstraZeneca R&D, Mölndal, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jmedgenet-2013-101897DOI Listing
July 2014

The (CCTTT)n microsatellite polymorphism in the NOS2 gene may influence lung cancer risk and long-term survival, especially in non-smokers.

Tumour Biol 2014 May 10;35(5):4425-34. Epub 2014 Jan 10.

Urology Laboratory, Department of Molecular Medicine and Surgery, Karolinska Institutet, 171 76, Stockholm, Sweden,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13277-013-1582-5DOI Listing
May 2014

Nitric oxide synthase (NOS) single nucleotide polymorphisms are associated with coronary heart disease and hypertension in the INTERGENE study.

Nitric Oxide 2014 May 5;39:1-7. Epub 2014 Apr 5.

Occupational and Environmental Medicine, Department of Public Health & Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; AstraZeneca R&D, Mölndal, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.niox.2014.03.164DOI Listing
May 2014

FTO genotype, physical activity, and coronary heart disease risk in Swedish men and women.

Circ Cardiovasc Genet 2014 Apr 12;7(2):171-7. Epub 2014 Mar 12.

Occupational and Environmental Medicine.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCGENETICS.111.000007DOI Listing
April 2014

Novel childhood asthma genes interact with in utero and early-life tobacco smoke exposure.

J Allergy Clin Immunol 2014 Mar 6;133(3):885-8. Epub 2013 Dec 6.

Department of Epidemiology, University of Groningen, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2013.08.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969577PMC
March 2014

Short-term exposure to ozone and levels of exhaled nitric oxide.

Epidemiology 2014 Jan;25(1):79-87

From the aOccupational and Environmental Medicine, Department of Public Health and Clinical Medicine, University of Umeå, Umeå, Sweden; bOccupational and Environmental Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden; and cAstraZeneca R&D, Mölndal, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/EDE.0000000000000002DOI Listing
January 2014

Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations.

Authors:
Nora Franceschini Ervin Fox Zhaogong Zhang Todd L Edwards Michael A Nalls Yun Ju Sung Bamidele O Tayo Yan V Sun Omri Gottesman Adebawole Adeyemo Andrew D Johnson J Hunter Young Ken Rice Qing Duan Fang Chen Yun Li Hua Tang Myriam Fornage Keith L Keene Jeanette S Andrews Jennifer A Smith Jessica D Faul Zhang Guangfa Wei Guo Yu Liu Sarah S Murray Solomon K Musani Sathanur Srinivasan Digna R Velez Edwards Heming Wang Lewis C Becker Pascal Bovet Murielle Bochud Ulrich Broeckel Michel Burnier Cara Carty Daniel I Chasman Georg Ehret Wei-Min Chen Guanjie Chen Wei Chen Jingzhong Ding Albert W Dreisbach Michele K Evans Xiuqing Guo Melissa E Garcia Rich Jensen Margaux F Keller Guillaume Lettre Vaneet Lotay Lisa W Martin Jason H Moore Alanna C Morrison Thomas H Mosley Adesola Ogunniyi Walter Palmas George Papanicolaou Alan Penman Joseph F Polak Paul M Ridker Babatunde Salako Andrew B Singleton Daniel Shriner Kent D Taylor Ramachandran Vasan Kerri Wiggins Scott M Williams Lisa R Yanek Wei Zhao Alan B Zonderman Diane M Becker Gerald Berenson Eric Boerwinkle Erwin Bottinger Mary Cushman Charles Eaton Fredrik Nyberg Gerardo Heiss Joel N Hirschhron Virginia J Howard Konrad J Karczewsk Matthew B Lanktree Kiang Liu Yongmei Liu Ruth Loos Karen Margolis Michael Snyder Bruce M Psaty Nicholas J Schork David R Weir Charles N Rotimi Michele M Sale Tamara Harris Sharon L R Kardia Steven C Hunt Donna Arnett Susan Redline Richard S Cooper Neil J Risch D C Rao Jerome I Rotter Aravinda Chakravarti Alex P Reiner Daniel Levy Brendan J Keating Xiaofeng Zhu

Am J Hum Genet 2013 Sep 22;93(3):545-54. Epub 2013 Aug 22.

Department of Epidemiology, University of North Carolina at Chapel Hill, NC 27599, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2013.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769920PMC
September 2013

Lack of association between SLCO1B1 polymorphisms and clinical myalgia following rosuvastatin therapy.

Am Heart J 2013 Jun 10;165(6):1008-14. Epub 2013 Apr 10.

Center for Cardiovascular Disease Prevention, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ahj.2013.01.025DOI Listing
June 2013

Investigation of novel genes for lung function in children and their interaction with tobacco smoke exposure: a preliminary report.

Acta Paediatr 2013 May 6;102(5):498-503. Epub 2013 Mar 6.

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/apa.12204DOI Listing
May 2013

Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.

Circ Cardiovasc Genet 2012 Dec 1;5(6):676-85. Epub 2012 Nov 1.

Center for Cardiovascular Disease Prevention, the Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCGENETICS.112.963314DOI Listing
December 2012

Similar DNA methylation pattern in lung tumours from smokers and never-smokers with second-hand tobacco smoke exposure.

Mutagenesis 2012 Jul 4;27(4):423-9. Epub 2012 Jan 4.

Faculty of Natural Sciences, Vilnius University, Ciurlionio 21, LT03101 Vilnius, Lithuania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/mutage/ger092DOI Listing
July 2012

Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial.

Circ Cardiovasc Genet 2012 Apr 13;5(2):257-64. Epub 2012 Feb 13.

Center for Cardiovascular Disease Prevention, Brigham and Women’s Hospital, 900 Commonwealth Ave. E, Boston, MA 02215, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCGENETICS.111.961144DOI Listing
April 2012

Single nucleotide polymorphisms in the NOS2 and NOS3 genes are associated with exhaled nitric oxide.

J Med Genet 2012 Mar;49(3):200-5

Occupational and Environmental Medicine, University of Gothenburg, Gothenburg, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jmedgenet-2011-100584DOI Listing
March 2012

Interaction of apolipoprotein E genotype with smoking and physical inactivity on coronary heart disease risk in men and women.

Atherosclerosis 2012 Feb 17;220(2):486-92. Epub 2011 Oct 17.

Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atherosclerosis.2011.10.011DOI Listing
February 2012

Pharmacogenetic determinants of statin-induced reductions in C-reactive protein.

Circ Cardiovasc Genet 2012 Feb 9;5(1):58-65. Epub 2012 Jan 9.

Center for Cardiovascular Disease Prevention, Division of Preventive Medicine, Brigham and Women’s Hospital, 900 Commonwealth Ave E, Boston, MA 02215, USA.

View Article

Download full-text PDF

Source
http://circgenetics.ahajournals.org/content/early/2012/01/09
Web Search
http://circgenetics.ahajournals.org/cgi/doi/10.1161/CIRCGENE
Publisher Site
http://dx.doi.org/10.1161/CIRCGENETICS.111.961847DOI Listing
February 2012

Blood pressure loci identified with a gene-centric array.

Authors:
Toby Johnson Tom R Gaunt Stephen J Newhouse Sandosh Padmanabhan Maciej Tomaszewski Meena Kumari Richard W Morris Ioanna Tzoulaki Eoin T O'Brien Neil R Poulter Peter Sever Denis C Shields Simon Thom Sasiwarang G Wannamethee Peter H Whincup Morris J Brown John M Connell Richard J Dobson Philip J Howard Charles A Mein Abiodun Onipinla Sue Shaw-Hawkins Yun Zhang George Davey Smith Ian N M Day Debbie A Lawlor Alison H Goodall F Gerald Fowkes Gonçalo R Abecasis Paul Elliott Vesela Gateva Peter S Braund Paul R Burton Christopher P Nelson Martin D Tobin Pim van der Harst Nicola Glorioso Hani Neuvrith Erika Salvi Jan A Staessen Andrea Stucchi Nabila Devos Xavier Jeunemaitre Pierre-François Plouin Jean Tichet Peeter Juhanson Elin Org Margus Putku Siim Sõber Gudrun Veldre Margus Viigimaa Anna Levinsson Annika Rosengren Dag S Thelle Claire E Hastie Thomas Hedner Wai K Lee Olle Melander Björn Wahlstrand Rebecca Hardy Andrew Wong Jackie A Cooper Jutta Palmen Li Chen Alexandre F R Stewart George A Wells Harm-Jan Westra Marcel G M Wolfs Robert Clarke Maria Grazia Franzosi Anuj Goel Anders Hamsten Mark Lathrop John F Peden Udo Seedorf Hugh Watkins Willem H Ouwehand Jennifer Sambrook Jonathan Stephens Juan-Pablo Casas Fotios Drenos Michael V Holmes Mika Kivimaki Sonia Shah Tina Shah Philippa J Talmud John Whittaker Chris Wallace Christian Delles Maris Laan Diana Kuh Steve E Humphries Fredrik Nyberg Daniele Cusi Robert Roberts Christopher Newton-Cheh Lude Franke Alice V Stanton Anna F Dominiczak Martin Farrall Aroon D Hingorani Nilesh J Samani Mark J Caulfield Patricia B Munroe

Am J Hum Genet 2011 Dec 17;89(6):688-700. Epub 2011 Nov 17.

Clinical Pharmacology and Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2011.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234370PMC
December 2011

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.

Authors:
Georg B Ehret Patricia B Munroe Kenneth M Rice Murielle Bochud Andrew D Johnson Daniel I Chasman Albert V Smith Martin D Tobin Germaine C Verwoert Shih-Jen Hwang Vasyl Pihur Peter Vollenweider Paul F O'Reilly Najaf Amin Jennifer L Bragg-Gresham Alexander Teumer Nicole L Glazer Lenore Launer Jing Hua Zhao Yurii Aulchenko Simon Heath Siim Sõber Afshin Parsa Jian'an Luan Pankaj Arora Abbas Dehghan Feng Zhang Gavin Lucas Andrew A Hicks Anne U Jackson John F Peden Toshiko Tanaka Sarah H Wild Igor Rudan Wilmar Igl Yuri Milaneschi Alex N Parker Cristiano Fava John C Chambers Ervin R Fox Meena Kumari Min Jin Go Pim van der Harst Wen Hong Linda Kao Marketa Sjögren D G Vinay Myriam Alexander Yasuharu Tabara Sue Shaw-Hawkins Peter H Whincup Yongmei Liu Gang Shi Johanna Kuusisto Bamidele Tayo Mark Seielstad Xueling Sim Khanh-Dung Hoang Nguyen Terho Lehtimäki Giuseppe Matullo Ying Wu Tom R Gaunt N Charlotte Onland-Moret Matthew N Cooper Carl G P Platou Elin Org Rebecca Hardy Santosh Dahgam Jutta Palmen Veronique Vitart Peter S Braund Tatiana Kuznetsova Cuno S P M Uiterwaal Adebowale Adeyemo Walter Palmas Harry Campbell Barbara Ludwig Maciej Tomaszewski Ioanna Tzoulaki Nicholette D Palmer Thor Aspelund Melissa Garcia Yen-Pei C Chang Jeffrey R O'Connell Nanette I Steinle Diederick E Grobbee Dan E Arking Sharon L Kardia Alanna C Morrison Dena Hernandez Samer Najjar Wendy L McArdle David Hadley Morris J Brown John M Connell Aroon D Hingorani Ian N M Day Debbie A Lawlor John P Beilby Robert W Lawrence Robert Clarke Jemma C Hopewell Halit Ongen Albert W Dreisbach Yali Li J Hunter Young Joshua C Bis Mika Kähönen Jorma Viikari Linda S Adair Nanette R Lee Ming-Huei Chen Matthias Olden Cristian Pattaro Judith A Hoffman Bolton Anna Köttgen Sven Bergmann Vincent Mooser Nish Chaturvedi Timothy M Frayling Muhammad Islam Tazeen H Jafar Jeanette Erdmann Smita R Kulkarni Stefan R Bornstein Jürgen Grässler Leif Groop Benjamin F Voight Johannes Kettunen Philip Howard Andrew Taylor Simonetta Guarrera Fulvio Ricceri Valur Emilsson Andrew Plump Inês Barroso Kay-Tee Khaw Alan B Weder Steven C Hunt Yan V Sun Richard N Bergman Francis S Collins Lori L Bonnycastle Laura J Scott Heather M Stringham Leena Peltonen Markus Perola Erkki Vartiainen Stefan-Martin Brand Jan A Staessen Thomas J Wang Paul R Burton Maria Soler Artigas Yanbin Dong Harold Snieder Xiaoling Wang Haidong Zhu Kurt K Lohman Megan E Rudock Susan R Heckbert Nicholas L Smith Kerri L Wiggins Ayo Doumatey Daniel Shriner Gudrun Veldre Margus Viigimaa Sanjay Kinra Dorairaj Prabhakaran Vikal Tripathy Carl D Langefeld Annika Rosengren Dag S Thelle Anna Maria Corsi Andrew Singleton Terrence Forrester Gina Hilton Colin A McKenzie Tunde Salako Naoharu Iwai Yoshikuni Kita Toshio Ogihara Takayoshi Ohkubo Tomonori Okamura Hirotsugu Ueshima Satoshi Umemura Susana Eyheramendy Thomas Meitinger H-Erich Wichmann Yoon Shin Cho Hyung-Lae Kim Jong-Young Lee James Scott Joban S Sehmi Weihua Zhang Bo Hedblad Peter Nilsson George Davey Smith Andrew Wong Narisu Narisu Alena Stančáková Leslie J Raffel Jie Yao Sekar Kathiresan Christopher J O'Donnell Stephen M Schwartz M Arfan Ikram W T Longstreth Thomas H Mosley Sudha Seshadri Nick R G Shrine Louise V Wain Mario A Morken Amy J Swift Jaana Laitinen Inga Prokopenko Paavo Zitting Jackie A Cooper Steve E Humphries John Danesh Asif Rasheed Anuj Goel Anders Hamsten Hugh Watkins Stephan J L Bakker Wiek H van Gilst Charles S Janipalli K Radha Mani Chittaranjan S Yajnik Albert Hofman Francesco U S Mattace-Raso Ben A Oostra Ayse Demirkan Aaron Isaacs Fernando Rivadeneira Edward G Lakatta Marco Orru Angelo Scuteri Mika Ala-Korpela Antti J Kangas Leo-Pekka Lyytikäinen Pasi Soininen Taru Tukiainen Peter Würtz Rick Twee-Hee Ong Marcus Dörr Heyo K Kroemer Uwe Völker Henry Völzke Pilar Galan Serge Hercberg Mark Lathrop Diana Zelenika Panos Deloukas Massimo Mangino Tim D Spector Guangju Zhai James F Meschia Michael A Nalls Pankaj Sharma Janos Terzic M V Kranthi Kumar Matthew Denniff Ewa Zukowska-Szczechowska Lynne E Wagenknecht F Gerald R Fowkes Fadi J Charchar Peter E H Schwarz Caroline Hayward Xiuqing Guo Charles Rotimi Michiel L Bots Eva Brand Nilesh J Samani Ozren Polasek Philippa J Talmud Fredrik Nyberg Diana Kuh Maris Laan Kristian Hveem Lyle J Palmer Yvonne T van der Schouw Juan P Casas Karen L Mohlke Paolo Vineis Olli Raitakari Santhi K Ganesh Tien Y Wong E Shyong Tai Richard S Cooper Markku Laakso Dabeeru C Rao Tamara B Harris Richard W Morris Anna F Dominiczak Mika Kivimaki Michael G Marmot Tetsuro Miki Danish Saleheen Giriraj R Chandak Josef Coresh Gerjan Navis Veikko Salomaa Bok-Ghee Han Xiaofeng Zhu Jaspal S Kooner Olle Melander Paul M Ridker Stefania Bandinelli Ulf B Gyllensten Alan F Wright James F Wilson Luigi Ferrucci Martin Farrall Jaakko Tuomilehto Peter P Pramstaller Roberto Elosua Nicole Soranzo Eric J G Sijbrands David Altshuler Ruth J F Loos Alan R Shuldiner Christian Gieger Pierre Meneton Andre G Uitterlinden Nicholas J Wareham Vilmundur Gudnason Jerome I Rotter Rainer Rettig Manuela Uda David P Strachan Jacqueline C M Witteman Anna-Liisa Hartikainen Jacques S Beckmann Eric Boerwinkle Ramachandran S Vasan Michael Boehnke Martin G Larson Marjo-Riitta Järvelin Bruce M Psaty Gonçalo R Abecasis Aravinda Chakravarti Paul Elliott Cornelia M van Duijn Christopher Newton-Cheh Daniel Levy Mark J Caulfield Toby Johnson

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

Authors:
María Soler Artigas Daan W Loth Louise V Wain Sina A Gharib Ma'en Obeidat Wenbo Tang Guangju Zhai Jing Hua Zhao Albert Vernon Smith Jennifer E Huffman Eva Albrecht Catherine M Jackson David M Evans Gemma Cadby Myriam Fornage Ani Manichaikul Lorna M Lopez Toby Johnson Melinda C Aldrich Thor Aspelund Inês Barroso Harry Campbell Patricia A Cassano David J Couper Gudny Eiriksdottir Nora Franceschini Melissa Garcia Christian Gieger Gauti Kjartan Gislason Ivica Grkovic Christopher J Hammond Dana B Hancock Tamara B Harris Adaikalavan Ramasamy Susan R Heckbert Markku Heliövaara Georg Homuth Pirro G Hysi Alan L James Stipan Jankovic Bonnie R Joubert Stefan Karrasch Norman Klopp Beate Koch Stephen B Kritchevsky Lenore J Launer Yongmei Liu Laura R Loehr Kurt Lohman Ruth J F Loos Thomas Lumley Khalid A Al Balushi Wei Q Ang R Graham Barr John Beilby John D Blakey Mladen Boban Vesna Boraska Jonas Brisman John R Britton Guy G Brusselle Cyrus Cooper Ivan Curjuric Santosh Dahgam Ian J Deary Shah Ebrahim Mark Eijgelsheim Clyde Francks Darya Gaysina Raquel Granell Xiangjun Gu John L Hankinson Rebecca Hardy Sarah E Harris John Henderson Amanda Henry Aroon D Hingorani Albert Hofman Patrick G Holt Jennie Hui Michael L Hunter Medea Imboden Karen A Jameson Shona M Kerr Ivana Kolcic Florian Kronenberg Jason Z Liu Jonathan Marchini Tricia McKeever Andrew D Morris Anna-Carin Olin David J Porteous Dirkje S Postma Stephen S Rich Susan M Ring Fernando Rivadeneira Thierry Rochat Avan Aihie Sayer Ian Sayers Peter D Sly George Davey Smith Akshay Sood John M Starr André G Uitterlinden Judith M Vonk S Goya Wannamethee Peter H Whincup Cisca Wijmenga O Dale Williams Andrew Wong Massimo Mangino Kristin D Marciante Wendy L McArdle Bernd Meibohm Alanna C Morrison Kari E North Ernst Omenaas Lyle J Palmer Kirsi H Pietiläinen Isabelle Pin Ozren Pola Sbreve Ek Anneli Pouta Bruce M Psaty Anna-Liisa Hartikainen Taina Rantanen Samuli Ripatti Jerome I Rotter Igor Rudan Alicja R Rudnicka Holger Schulz So-Youn Shin Tim D Spector Ida Surakka Veronique Vitart Henry Völzke Nicholas J Wareham Nicole M Warrington H-Erich Wichmann Sarah H Wild Jemma B Wilk Matthias Wjst Alan F Wright Lina Zgaga Tatijana Zemunik Craig E Pennell Fredrik Nyberg Diana Kuh John W Holloway H Marike Boezen Debbie A Lawlor Richard W Morris Nicole Probst-Hensch Jaakko Kaprio James F Wilson Caroline Hayward Mika Kähönen Joachim Heinrich Arthur W Musk Deborah L Jarvis Sven Gläser Marjo-Riitta Järvelin Bruno H Ch Stricker Paul Elliott George T O'Connor David P Strachan Stephanie J London Ian P Hall Vilmundur Gudnason Martin D Tobin

Nat Genet 2011 Sep 25;43(11):1082-90. Epub 2011 Sep 25.

Department of Health Sciences, University of Leicester, Leicester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267376PMC
September 2011

Air pollution exposure--a trigger for myocardial infarction?

Int J Environ Res Public Health 2010 04 31;7(4):1486-99. Epub 2010 Mar 31.

Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijerph7041486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872334PMC
April 2010

Genome-wide association study identifies five loci associated with lung function.

Nat Genet 2010 Jan 13;42(1):36-44. Epub 2009 Dec 13.

Departments of Health Sciences and Genetics, Adrian Building, University of Leicester, Leicester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862965PMC
January 2010

Fibrinogen genes modify the fibrinogen response to ambient particulate matter.

Am J Respir Crit Care Med 2009 Mar 8;179(6):484-91. Epub 2009 Jan 8.

Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Epidemiology, Ingolstaedter Landstrasse, Neuherberg 85764, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.200805-751OCDOI Listing
March 2009

Traffic-related air pollution and childhood respiratory symptoms, function and allergies.

Epidemiology 2008 May;19(3):401-8

Department of Occupational and Environmental Health, Stockholm County Council, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/EDE.0b013e31816a1ce3DOI Listing
May 2008

A case-crossover analysis of out-of-hospital coronary deaths and air pollution in Rome, Italy.

Am J Respir Crit Care Med 2005 Dec 30;172(12):1549-55. Epub 2005 Jun 30.

Department of Epidemiology, Rome E Local Health Authority, Via Santa Costanza 53, 00198 Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.200412-1726OCDOI Listing
December 2005

Haplotypes of G protein-coupled receptor 154 are associated with childhood allergy and asthma.

Am J Respir Crit Care Med 2005 May 11;171(10):1089-95. Epub 2005 Feb 11.

Institute of Environmental Medicine, Centre for Allergy Research, and Department of Biosciences, Karolinska Institutet, Box 210, Stockholm SE-171 77, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.200410-1317OCDOI Listing
May 2005

Influence of CYP1A1, GSTM1, GSTT1, and NQO1 genotypes and cumulative smoking dose on lung cancer risk in a Swedish population.

Cancer Epidemiol Biomarkers Prev 2004 Jun;13(6):908-14

Work Environment Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

View Article

Download full-text PDF

Source
June 2004

Contribution of environmental factors to cancer risk.

Br Med Bull 2003 ;68:71-94

International Agency for Research on Cancer, Lyon, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bmp/ldg023DOI Listing
April 2004

Air pollution and lung cancer mortality in the vicinity of a nonferrous metal smelter in Sweden.

Int J Cancer 2003 Nov;107(3):448-52

Department of Environmental Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ijc.11412DOI Listing
November 2003

Dietary fruit and vegetables protect against somatic mutation in vivo, but low or high intake of carotenoids does not.

Carcinogenesis 2003 Apr;24(4):689-96

Division of Environmental Epidemiology, Institute of Environmental Medicine, Karolinska Institute, Box 210, SE-171 77 Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/carcin/bgg017DOI Listing
April 2003

Influence of common XPD and XRCC1 variant alleles on p53 mutations in lung tumors.

Environ Mol Mutagen 2003 ;41(1):37-42

Department of Biosciences at Novum, Karolinska Institute, S-14157 Huddinge, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/em.10128DOI Listing
March 2003

Glass-based radon-exposure assessment and lung cancer risk.

J Expo Anal Environ Epidemiol 2002 Sep;12(5):344-54

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.jea.7500236DOI Listing
September 2002

The XPD variant alleles are associated with increased aromatic DNA adduct level and lung cancer risk.

Carcinogenesis 2002 Apr;23(4):599-603

Department of Biosciences at Novum, Karolinska Institute, S-141 57 Huddinge, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/carcin/23.4.599DOI Listing
April 2002