Fredrick M Wigley

Fredrick M Wigley

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Fredrick M Wigley

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Longitudinal assessment of interstitial lung disease in single lung transplant recipients with scleroderma.

Rheumatology (Oxford) 2019 Aug 27. Epub 2019 Aug 27.

Department of Medicine, Division of Clinical and Molecular Rheumatology, Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1093/rheumatology/kez341DOI Listing
August 2019

Epigenetic activation and memory at a enhancer in systemic sclerosis.

Sci Transl Med 2019 Jun;11(497)

McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1126/scitranslmed.aaw0790DOI Listing
June 2019

Clinical and Molecular Phenotyping in Scleromyxedema Pre- and Post-Treatment with Intravenous Immunoglobulin.

Arthritis Care Res (Hoboken) 2019 Apr 22. Epub 2019 Apr 22.

Johns Hopkins University School of Medicine, Division of Rheumatology, Baltimore, MD.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/acr.23908
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http://dx.doi.org/10.1002/acr.23908DOI Listing
April 2019

Determining the Risk Factors and Clinical Features Associated With Severe Gastrointestinal Dysmotility in Systemic Sclerosis.

Arthritis Care Res (Hoboken) 2018 09 6;70(9):1385-1392. Epub 2018 Aug 6.

Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1002/acr.23479DOI Listing
September 2018

Vascular complications in systemic sclerosis: a prospective cohort study.

Clin Rheumatol 2018 Sep 26;37(9):2429-2437. Epub 2018 May 26.

Division of Rheumatology, Johns Hopkins University School of Medicine, 5200 Eastern Ave, MFL Bldg, Center Tower, Suite 4100, Baltimore, MD, 21224, USA.

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http://dx.doi.org/10.1007/s10067-018-4148-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166238PMC
September 2018

Pharmacotherapy Options in the Management of Raynaud's Phenomenon.

Curr Treatm Opt Rheumatol 2018 Sep 4;4(3):235-254. Epub 2018 Jul 4.

Division of Rheumatology, Johns Hopkins University, 5200 Eastern Avenue, MFL Building, Center Tower Ste. 4100, Baltimore, MD, 21224.

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http://dx.doi.org/10.1007/s40674-018-0102-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752040PMC
September 2018

Pyridostigmine for the treatment of gastrointestinal symptoms in systemic sclerosis.

Semin Arthritis Rheum 2018 08 5;48(1):111-116. Epub 2018 Jan 5.

Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.1016/j.semarthrit.2017.12.007DOI Listing
August 2018

Autoantibodies and scleroderma phenotype define subgroups at high-risk and low-risk for cancer.

Ann Rheum Dis 2018 08 20;77(8):1179-1186. Epub 2018 Apr 20.

Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1136/annrheumdis-2018-212999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272061PMC
August 2018

Evaluation of cancer-associated myositis and scleroderma autoantibodies in breast cancer patients without rheumatic disease.

Clin Exp Rheumatol 2017 Sep-Oct;35 Suppl 106(4):71-74. Epub 2017 Jun 19.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore; and Division of Medical Oncology, Department of Medicine, Johns Hopkins University School of Medicine Baltimore MD, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947318PMC
December 2017

Editorial: Clinical Trials in Raynaud's Phenomenon: A Spoonful of Sugar (Pill) Makes the Medicine Go Down (in Flames).

Arthritis Rheumatol 2017 12 10;69(12):2256-2258. Epub 2017 Nov 10.

Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1002/art.40307DOI Listing
December 2017

Association of Fibrosing Myopathy in Systemic Sclerosis and Higher Mortality.

Arthritis Care Res (Hoboken) 2017 11;69(11):1764-1770

Johns Hopkins University School of Medicine, Baltimore, Maryland, and National Institute of Arthritis and Musculoskeletal and Skin Diseases/NIH, Bethesda, Maryland.

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http://dx.doi.org/10.1002/acr.23291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791890PMC
November 2017

Treating Raynaud phenomenon: Beyond staying warm.

Cleve Clin J Med 2017 10;84(10):797-804

Department of Medicine, Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.3949/ccjm.84a.17025DOI Listing
October 2017

Reply.

Arthritis Rheumatol 2017 09 11;69(9):1915-1916. Epub 2017 Jul 11.

Johns Hopkins University School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.1002/art.40132DOI Listing
September 2017

Exhaled nitric oxide in pulmonary arterial hypertension associated with systemic sclerosis.

Pulm Circ 2016 Dec;6(4):545-550

Division of Pulmonary and Critical Care Medicine, Spectrum Health and Michigan State University College of Human Medicine, Grand Rapids, Michigan, USA.

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http://dx.doi.org/10.1086/688768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210065PMC
December 2016

Independent Association of Severity of Muscle Weakness With Disability as Measured by the Health Assessment Questionnaire Disability Index in Scleroderma.

Arthritis Care Res (Hoboken) 2016 11 9;68(11):1695-1703. Epub 2016 Oct 9.

Julie J. Paik, MD, MHS, Fredrick M. Wigley, MD, Laura K. Hummers, MD, ScM: Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1002/acr.22870DOI Listing
November 2016

Thrombotic complications after radial arterial line placement in systemic sclerosis: A case series.

Semin Arthritis Rheum 2016 10 31;46(2):196-199. Epub 2016 Mar 31.

Division of Rheumatology, Johns Hopkins University School of Medicine, 5200 Eastern Ave., MFL-Center Tower, Suite 4500, Baltimore, MD 21224.

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http://dx.doi.org/10.1016/j.semarthrit.2016.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035550PMC
October 2016

Symptomatic and Electrodiagnostic Features of Peripheral Neuropathy in Scleroderma.

Arthritis Care Res (Hoboken) 2016 08;68(8):1150-7

Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1002/acr.22818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261345PMC
August 2016

Raynaud's Phenomenon.

N Engl J Med 2016 Aug;375(6):556-65

From the Division of Rheumatology (F.M.W.) and the Department of Anesthesiology and Critical Care Medicine (N.A.F.), Johns Hopkins University School of Medicine, Baltimore.

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http://dx.doi.org/10.1056/NEJMra1507638DOI Listing
August 2016

Right Ventricular Functional Reserve in Pulmonary Arterial Hypertension.

Circulation 2016 Jun 11;133(24):2413-22. Epub 2016 May 11.

From Divisions of Cardiology (S.H., B.A.H., E.T., A.C.B., P.S.R., D.A.K., R.J.T.), Pulmonary and Critical Care (S.C.M., R.L.D., T.M.K., P.M.H.), and Rheumatology (L.K.H., A.A.S., Z.M., F.M.W.), Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD; and Departments of Radiology (C.P.C.-V., S.L.Z.) and Biomedical Engineering (D.A.K.), Johns Hopkins Medical Institutions, Baltimore, MD.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.022082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907868PMC
June 2016

Unique Abnormalities in Right Ventricular Longitudinal Strain in Systemic Sclerosis Patients.

Circ Cardiovasc Imaging 2016 06 7;9(6). Epub 2016 Jun 7.

From the Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD (M.M., V.K.T., R.J.T., T.P.A.), Division of Pulmonary and Critical Care Medicine (S.-E.C.), and Division of Rheumatology (L.K.H., F.M.W., A.A.S.), Johns Hopkins University School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.1161/CIRCIMAGING.115.003792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902176PMC
June 2016

Frequency of circulating topoisomerase-I-specific CD4 T cells predicts presence and progression of interstitial lung disease in scleroderma.

Arthritis Res Ther 2016 05 4;18(1):99. Epub 2016 May 4.

Department of Medicine, Division of Rheumatology, University of California, San Francisco, 513 Parnassus Avenue, Med Sci, S-847, San Francisco, CA, 94143, USA.

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http://dx.doi.org/10.1186/s13075-016-0993-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857293PMC
May 2016

Editorial: Scleroderma: Bringing a Disease From Black-and-White Into Technicolor.

Arthritis Rheumatol 2015 Dec;67(12):3101-3

Johns Hopkins University, Baltimore, Maryland.

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http://dx.doi.org/10.1002/art.39310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757897PMC
December 2015

Spectrum of Muscle Histopathologic Findings in Forty-Two Scleroderma Patients With Weakness.

Arthritis Care Res (Hoboken) 2015 Oct;67(10):1416-25

Johns Hopkins University School of Medicine and National Institute of Arthritis and Musculoskeletal and Skin Diseases/NIH, Bethesda, Maryland.

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http://dx.doi.org/10.1002/acr.22620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580502PMC
October 2015

Pilot study to determine whether transient receptor potential melastatin type 8 (TRPM8) antibodies are detected in scleroderma.

Clin Exp Rheumatol 2015 Jul-Aug;33(4 Suppl 91):S123-6. Epub 2015 Aug 5.

Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567034PMC
October 2015

Prediction and impact of attacks of Raynaud's phenomenon, as judged by patient perception.

Rheumatology (Oxford) 2015 Aug 9;54(8):1443-7. Epub 2015 Mar 9.

Centre for Musculoskeletal Research, Salford Royal NHS Foundation Trust, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.1093/rheumatology/kev002DOI Listing
August 2015

Management of Raynaud Phenomenon and Digital Ulcers in Scleroderma.

Rheum Dis Clin North Am 2015 Aug 23;41(3):419-38. Epub 2015 May 23.

Division of Rheumatology, Johns Hopkins University School of Medicine, 5200 Eastern Avenue, Suite 4100, Mason F. Lord Building, Center Tower, Baltimore, MD 21224, USA. Electronic address:

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http://dx.doi.org/10.1016/j.rdc.2015.04.005DOI Listing
August 2015

Biomarkers of pulmonary hypertension in patients with scleroderma: a case-control study.

Arthritis Res Ther 2015 Aug 6;17:201. Epub 2015 Aug 6.

Division of Rheumatology, Department of Medicine, Johns Hopkins University, 5200 Eastern Avenue, Mason F. Lord Building, Center Tower, Suite 4000, Baltimore, MD, 21224, USA.

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http://dx.doi.org/10.1186/s13075-015-0712-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527208PMC
August 2015

Intravenous immunoglobulin may be an effective therapy for refractory, active diffuse cutaneous systemic sclerosis.

J Rheumatol 2015 Feb 29;42(2):236-42. Epub 2014 Nov 29.

From the Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.C.L. Poelman, BA; L.K. Hummers, MD, ScM, Associate Professor of Medicine; F.M. Wigley, MD, Professor of Medicine; C. Anderson, MS; F. Boin, MD, Assistant Professor of Medicine; A.A. Shah, MD, MHS, Assistant Professor of Medicine, Division of Rheumatology, Johns Hopkins University School of Medicine.

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http://dx.doi.org/10.3899/jrheum.140833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314512PMC
February 2015

Severity of systemic sclerosis-associated pulmonary arterial hypertension in African Americans.

Medicine (Baltimore) 2014 Jul;93(5):177-85

Divisions of Pulmonary and Critical Care Medicine (IB, SCM, DB, TMK, HC, TH, NC, ALZ, RD, REG, PMH), General Internal Medicine (MS, FMW), Rheumatology (LKH), and Cardiology (RJT, DAK), Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) (IB), Barcelona, Spain; and Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES) (IB), Spain.

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http://dx.doi.org/10.1097/MD.0000000000000032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602454PMC
July 2014

The degree of skin involvement identifies distinct lung disease outcomes and survival in systemic sclerosis.

Ann Rheum Dis 2014 Jun 20;73(6):1060-6. Epub 2013 Apr 20.

Johns Hopkins University School of Medicine, , Baltimore, Maryland, USA.

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http://dx.doi.org/10.1136/annrheumdis-2012-202849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776325PMC
June 2014

Myopathy in scleroderma, its identification, prevalence, and treatment: lessons learned from cohort studies.

Curr Opin Rheumatol 2014 Mar;26(2):124-30

aDepartment of Medicine bDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/BOR.0000000000000024DOI Listing
March 2014

Novel investigational agents for the treatment of scleroderma.

Expert Opin Investig Drugs 2014 Feb 22;23(2):183-98. Epub 2013 Nov 22.

Johns Hopkins University, Medicine/Rheumatology , 55200 Eastern Avenue, MFL Center Tower, Suite 5300, Baltimore, MD 21224 , USA.

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http://dx.doi.org/10.1517/13543784.2014.848852DOI Listing
February 2014

Association of the autoimmune disease scleroderma with an immunologic response to cancer.

Science 2014 Jan 5;343(6167):152-7. Epub 2013 Dec 5.

Ludwig Center, the Howard Hughes Medical Institutions, and the Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1126/science.1246886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038033PMC
January 2014

Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis.

Am J Hum Genet 2014 Jan;94(1):47-61

Instituto de Parasitología y Biomedicina López-Neyra, Consejo Superior de Investigaciones Científicas, Granada 18016, Spain.

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http://eprints.gla.ac.uk/104672/1/104672.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S000292971300571
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http://dx.doi.org/10.1016/j.ajhg.2013.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882906PMC
January 2014

A multi-centre, blinded, randomised, placebo-controlled, laboratory-based study of MQX-503, a novel topical gel formulation of nitroglycerine, in patients with Raynaud phenomenon.

Ann Rheum Dis 2013 Dec 25;72(12):1962-7. Epub 2012 Dec 25.

Department of Medicine, Division of Rheumatology, Johns Hopkins University School of Medicine, , Baltimore, Maryland, USA.

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http://dx.doi.org/10.1136/annrheumdis-2012-201536DOI Listing
December 2013

Integrin-modulating therapy prevents fibrosis and autoimmunity in mouse models of scleroderma.

Nature 2013 Nov 9;503(7474):126-30. Epub 2013 Oct 9.

McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1038/nature12614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992987PMC
November 2013

Review: evidence that systemic sclerosis is a vascular disease.

Arthritis Rheum 2013 Aug;65(8):1953-62

University of Florence, Florence, Italy.

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http://dx.doi.org/10.1002/art.37988DOI Listing
August 2013

Changes in estimated right ventricular systolic pressure predict mortality and pulmonary hypertension in a cohort of scleroderma patients.

Ann Rheum Dis 2013 Jul 11;72(7):1136-40. Epub 2012 Aug 11.

Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1136/annrheumdis-2012-201861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839570PMC
July 2013

My approach to the treatment of scleroderma.

Mayo Clin Proc 2013 Apr;88(4):377-93

Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.mayocp.2013.01.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666163PMC
April 2013

Efficacy of Rho kinase inhibitor fasudil in secondary Raynaud's phenomenon.

Arthritis Care Res (Hoboken) 2012 Jun 24;64(6):925-9. Epub 2012 Jan 24.

Division of Rheumatology, JohnsHopkins University School of Medicine, 5200 Eastern Avenue, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1002/acr.21622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343172PMC
June 2012

Late-age onset systemic sclerosis.

J Rheumatol 2011 Jul 17;38(7):1317-25. Epub 2011 Jun 17.

Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.

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http://www.jrheum.org/cgi/doi/10.3899/jrheum.100956
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http://dx.doi.org/10.3899/jrheum.100956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136880PMC
July 2011

The association of body image dissatisfaction and pain with reduced sexual function in women with systemic sclerosis.

Rheumatology (Oxford) 2011 Jun 27;50(6):1125-30. Epub 2011 Jan 27.

Department of Psychiatry, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1093/rheumatology/keq443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093929PMC
June 2011

Long-term experience of mycophenolate mofetil for treatment of diffuse cutaneous systemic sclerosis.

Ann Rheum Dis 2011 Jun 6;70(6):1104-7. Epub 2011 Mar 6.

Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1136/ard.2010.142000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828653PMC
June 2011

Development and validation of the brief-satisfaction with appearance scale for systemic sclerosis.

Arthritis Care Res (Hoboken) 2010 Dec 27;62(12):1779-86. Epub 2010 Jul 27.

McGill University and Lady Davis Institute of the Jewish General Hospital, Montréal, Québec, Canada.

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http://doi.wiley.com/10.1002/acr.20307
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http://dx.doi.org/10.1002/acr.20307DOI Listing
December 2010

Hemodynamic predictors of survival in scleroderma-related pulmonary arterial hypertension.

Am J Respir Crit Care Med 2010 Jul 25;182(2):252-60. Epub 2010 Mar 25.

MD, Division of Pulmonary and Critical Care Medicine, 1830 E Monument St, Fifth Floor, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1164/rccm.200912-1820OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913238PMC
July 2010

Thoracic outlet syndrome secondary to localized scleroderma treated with botulinum toxin injection.

Arthritis Care Res (Hoboken) 2010 Mar;62(3):430-3

Johns Hopkins School of Medicine, Baltimore, Maryland 21224, USA.

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http://dx.doi.org/10.1002/acr.20099DOI Listing
March 2010

Telangiectases in scleroderma: a potential clinical marker of pulmonary arterial hypertension.

J Rheumatol 2010 Jan 1;37(1):98-104. Epub 2009 Dec 1.

Division of Rheumatology, Johns Hopkins University School of Medicine, 5200 Eastern Avenue, Mason F. Lord Building Center Tower, Suite 4100, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.3899/jrheum.090697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419384PMC
January 2010

Raynaud's phenomenon and digital ischemia: a practical approach to risk stratification, diagnosis and management.

Int J Clin Rheumtol 2010;5(3):355-370

Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD 21224.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624318PMC
January 2010

Resolution of pansclerotic morphea after treatment with antithymocyte globulin.

Nat Rev Rheumatol 2009 Sep;5(9):513-6

Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.

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http://www.nature.com/articles/nrrheum.2009.159
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http://dx.doi.org/10.1038/nrrheum.2009.159DOI Listing
September 2009

Vascular disease in scleroderma.

Clin Rev Allergy Immunol 2009 Jun;36(2-3):150-75

Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1007/s12016-008-8106-xDOI Listing
June 2009

Diffuse fasciitis with eosinophilia developing after local irradiation for breast cancer.

Clin Rheumatol 2009 Jun 18;28(6):729-32. Epub 2009 Feb 18.

Department of Dermatology, Johns Hopkins Medical Institutions, 601 North Caroline Street, 6th Floor, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1007/s10067-009-1122-2DOI Listing
June 2009

Abnormalities in the regulators of angiogenesis in patients with scleroderma.

J Rheumatol 2009 Mar 17;36(3):576-82. Epub 2009 Feb 17.

Department of Medicine, Johns Hopkins University, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.3899/jrheum.080516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020014PMC
March 2009

"Still" ill?

Am J Med 2008 Jun;121(6):491-3

Division of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1016/j.amjmed.2008.02.010DOI Listing
June 2008

T cell polarization identifies distinct clinical phenotypes in scleroderma lung disease.

Arthritis Rheum 2008 Apr;58(4):1165-74

Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA.

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http://dx.doi.org/10.1002/art.23406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662772PMC
April 2008

Systemic sclerosis (scleroderma) is unique among our rheumatic diseases. Preface.

Rheum Dis Clin North Am 2008 Feb;34(1):xi-xiii

Johns Hopkins Scleroderma Center, John Hopkins University, 5200 Eastern Avenue, Suite 4100, Mason F. Lord Building, Center Tower, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1016/j.rdc.2008.01.002DOI Listing
February 2008

Often forgotten manifestations of systemic sclerosis.

Rheum Dis Clin North Am 2008 Feb;34(1):221-38; ix

Division of Rheumatology, Johns Hopkins University, 5200 Eastern Avenue, Mason F. Lord Building, Center Tower, Suite 4100, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1016/j.rdc.2007.10.002DOI Listing
February 2008

Scleromyxedema: a case series highlighting long-term outcomes of treatment with intravenous immunoglobulin (IVIG).

Medicine (Baltimore) 2008 Jan;87(1):10-20

Department of Medicine, Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1097/MD.0b013e3181630835DOI Listing
January 2008

Persistence of abnormal bronchoalveolar lavage findings after cyclophosphamide treatment in scleroderma patients with interstitial lung disease.

Arthritis Rheum 2007 Dec;56(12):4195-202

Johns Hopkins University School of Medicine, 5200 Eastern Avenue, Baltimore, MD 21224, USA.

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http://doi.wiley.com/10.1002/art.23077
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http://dx.doi.org/10.1002/art.23077DOI Listing
December 2007

Current drug therapy for scleroderma and secondary Raynaud's phenomenon: evidence-based review.

Curr Opin Rheumatol 2007 Nov;19(6):611-8

Wolters Kluwer Health | Adis, Auckland, New Zealand.

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http://dx.doi.org/10.1097/BOR.0b013e3282f13137DOI Listing
November 2007

Antiangiogenic plasma activity in patients with systemic sclerosis.

Arthritis Rheum 2007 Oct;56(10):3448-58

Angiogenesis Research Center, Dartmouth Medical School, Lebanon, New Hampshire 03756, USA.

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http://doi.wiley.com/10.1002/art.22861
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http://dx.doi.org/10.1002/art.22861DOI Listing
October 2007

Autoimmune disorders: nail signs and therapeutic approaches.

Dermatol Ther 2007 Jan-Feb;20(1):17-30

Columbia University Medical Center, New York, New York 10032, USA.

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http://dx.doi.org/10.1111/j.1529-8019.2007.00108.xDOI Listing
May 2007

Bullous pemphigoid in a patient with systemic sclerosis (scleroderma).

J Rheumatol 2006 Oct;33(10):2098

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October 2006

Antineutrophil cytoplasmic antibody-positive crescentic glomerulonephritis in scleroderma--a different kind of renal crisis.

J Rheumatol 2006 Sep 1;33(9):1886-8. Epub 2006 Jul 1.

Division of Rheumatology and Immunology, Medical University of South Carolina, Charleston, South Carolina 29425, USA.

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September 2006

Natural history of mild-moderate pulmonary hypertension and the risk factors for severe pulmonary hypertension in scleroderma.

J Rheumatol 2006 Feb;33(2):269-74

Division of Pulmonary and Critical Care Medicine, University of New Mexico, Albuquerque, 87131, USA.

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February 2006

Paclitaxel modulates TGFbeta signaling in scleroderma skin grafts in immunodeficient mice.

PLoS Med 2005 Dec 1;2(12):e354. Epub 2005 Nov 1.

Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.0020354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1274282PMC
December 2005

Evaluation of topoisomerase-1-specific CD8+ T-cell response in systemic sclerosis.

Ann N Y Acad Sci 2005 Dec;1062:137-45

Division of Rheumatology, The Johns Hopkins University School of Medicine, 5200 Eastern Ave., Mason F. Lord Bldg., Center Tower, Ste. 4100, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1196/annals.1358.016DOI Listing
December 2005

Understanding, assessing and treating Raynaud's phenomenon.

Curr Opin Rheumatol 2005 Nov;17(6):752-60

Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA.

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http://dx.doi.org/10.1097/01.bor.0000179944.35400.6eDOI Listing
November 2005

Long-term outcome of bosentan treatment in idiopathic pulmonary arterial hypertension and pulmonary arterial hypertension associated with the scleroderma spectrum of diseases.

J Heart Lung Transplant 2005 Oct;24(10):1626-31

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1016/j.healun.2004.12.113DOI Listing
October 2005

Raynaud's phenomenon in mixed connective tissue disease.

Rheum Dis Clin North Am 2005 Aug;31(3):465-81, vi

Division of Rheumatology, Johns Hopkins School of Medicine, 5200 Eastern Avenue, Suite 4100, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1016/j.rdc.2005.04.006DOI Listing
August 2005