Publications by authors named "Frederik Roels"

15Publications

Running Exercise in Obese Pregnancies Prevents IL-6 Trans-signaling in Male Offspring.

Med Sci Sports Exerc 2016 May;48(5):829-38

1Department of Pediatrics, University Hospital of Cologne, Cologne, GERMANY; 2Department of Ophthalmology, University Hospital of Cologne, Cologne, GERMANY; 3Cologne Centre for Prevention in Childhood and Youth, Heart Centre Cologne, University Hospital of Cologne, Cologne, GERMANY; and 4Department for Physical Activity in Public Health, Institute of Movement and Neurosciences, German Sport University Cologne, Cologne, GERMANY.

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http://dx.doi.org/10.1249/MSS.0000000000000835DOI Listing
May 2016

Transcription factor activating protein 2 beta (TFAP2B) mediates noradrenergic neuronal differentiation in neuroblastoma.

Mol Oncol 2016 Feb 7;10(2):344-59. Epub 2015 Nov 7.

Department of Pediatric Oncology and Hematology, University Children's Hospital of Cologne, Germany; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Germany; Max Planck Institute for Metabolism Research, Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2015.10.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528952PMC
February 2016

Mutational dynamics between primary and relapse neuroblastomas.

Nat Genet 2015 Aug 29;47(8):872-7. Epub 2015 Jun 29.

1] Pediatric Oncology and Hematology, University Children's Hospital Essen, University of Duisburg-Essen, Essen, Germany. [2] Pediatric Oncology and Hematology, Charité University Medicine, Berlin, Germany. [3] German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany.

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http://search.proquest.com/openview/bef3fe020af3cd6708016aba
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http://dx.doi.org/10.1038/ng.3349DOI Listing
August 2015

FOXP1 inhibits cell growth and attenuates tumorigenicity of neuroblastoma.

BMC Cancer 2014 Nov 18;14:840. Epub 2014 Nov 18.

Department of Pediatric Oncology and Hematology and Center for Molecular Medicine Cologne (CMMC), Children's Hospital, University of Cologne, Kerpener Straße 62, Cologne 50924, Germany.

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http://dx.doi.org/10.1186/1471-2407-14-840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251948PMC
November 2014

Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles.

Nature 2014 Jul 9;511(7510):483-7. Epub 2014 Jul 9.

1] Theodor Boveri Institute, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany [2] Comprehensive Cancer Center Mainfranken, University of Würzburg, Josef-Schneider-Str. 6, 97080 Würzburg, Germany [3].

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http://dx.doi.org/10.1038/nature13473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879323PMC
July 2014

GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3.

Cancer Res 2014 May 13;74(9):2604-16. Epub 2014 Jan 13.

Authors' Affiliations: Clinical Cooperation Unit Pediatric Oncology; Departments of Biostatistics and Tumor Genetics; Clinical Cooperation Unit Neuropathology; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ); Departments of Neuropathology and Pediatric Hematology and Oncology, University of Heidelberg, Heidelberg; Transcriptome Analysis Laboratory, University of Goettingen, Goettingen; St. Lukas Klinik Solingen, Solingen; Department of Pediatric Hematology and Oncology; and Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1904DOI Listing
May 2014