Frederik Barkhof

Frederik Barkhof

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Frederik Barkhof

Publications by authors named "Frederik Barkhof"

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Is retinal vasculature a biomarker in amyloid proven Alzheimer's disease?

Alzheimers Dement (Amst) 2019 Dec 10;11:383-391. Epub 2019 May 10.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.dadm.2019.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517376PMC
December 2019

Retinal thickness as a potential biomarker in patients with amyloid-proven early- and late-onset Alzheimer's disease.

Alzheimers Dement (Amst) 2019 Dec 18;11:463-471. Epub 2019 Jun 18.

Department of Neurology, Alzheimer Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.dadm.2019.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584766PMC
December 2019

Cortical cerebral blood flow in ageing: effects of haematocrit, sex, ethnicity and diabetes.

Eur Radiol 2019 Oct 18;29(10):5549-5558. Epub 2019 Mar 18.

Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1007/s00330-019-06096-wDOI Listing
October 2019

Radiomics in multiple sclerosis and neuromyelitis optica spectrum disorder.

Eur Radiol 2019 Sep 15;29(9):4670-4677. Epub 2019 Feb 15.

Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, People's Republic of China.

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http://dx.doi.org/10.1007/s00330-019-06026-wDOI Listing
September 2019

Gray matter T1-w/T2-w ratios are higher in Alzheimer's disease.

Hum Brain Mapp 2019 Sep 3;40(13):3900-3909. Epub 2019 Jun 3.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/hbm.24638DOI Listing
September 2019

The quantitative neuroradiology initiative framework: application to dementia.

Br J Radiol 2019 Sep 1;92(1101):20190365. Epub 2019 Aug 1.

1Centre for Medical Image Computing (CMIC), Department of Medical Physics and Bioengineering, University College London, London, United Kingdom.

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http://dx.doi.org/10.1259/bjr.20190365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732931PMC
September 2019

Onset of clinical and MRI efficacy of ocrelizumab in relapsing multiple sclerosis.

Neurology 2019 Sep 4. Epub 2019 Sep 4.

From the Department of Radiology and Nuclear Medicine (F.B.), VU University Medical Centre, Amsterdam, the Netherlands; UCL Institutes of Healthcare Engineering and Neurology (F.B.), London, UK; Neurologic Clinic and Policlinic, Departments of Medicine, Clinical Research, Biomedicine and Biomedical Engineering (L.K.), University Hospital Basel, University of Basel, Switzerland; Department of Neurology (J.S.W.), McGovern Medical School, UTHealth, Houston, TX; Department of Radiology (D.K.B.L.), University of British Columbia, Vancouver, Canada; Department of Neurology and Center for Neuroinflammation and Experimental Therapeutics (A.B.-O.), University of Pennsylvania, Philadelphia; Department of Neurology, Medical Faculty (H.-P.H.), Heinrich-Heine University Düsseldorf, Germany; F. Hoffmann-La Roche Ltd. (S.B., A.S., J.N., H.K.), Basel, Switzerland; Genentech, Inc. (J.H., L.J.), South San Francisco; and Department of Neurology (S.L.H.), University of California, San Francisco. During completion of the work related to this article, S. Belachew was an employee of F. Hoffmann-La Roche Ltd.; his current affiliation is Biogen, Cambridge, MA.

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http://dx.doi.org/10.1212/WNL.0000000000008189DOI Listing
September 2019

Cortical atrophy accelerates as cognitive decline worsens in multiple sclerosis.

Neurology 2019 Sep 4. Epub 2019 Sep 4.

From the Departments of Anatomy & Neurosciences (A.J.C.E., M.D.S., K.A.M., H.E.H., M.M.S., J.J.G.G.), Radiology and Nuclear Medicine (I.D., J.W.P., F.B., H.V.), and Neurology (I.D., B.M.J.U.), Amsterdam Neuroscience, MS Center Amsterdam, Amsterdam UMC, Location VUmc, the Netherlands; and Institutes of Neurology and Healthcare Engineering (F.B.), UCL, London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000008198DOI Listing
September 2019

Reproducing Fingerprints: A Step toward Clinical Adoption.

Radiology 2019 Aug 18;292(2):438-439. Epub 2019 Jun 18.

From the Center for Medical Image Computing and Institute of Neurology, University College London, London, England (F.B., G.J.M.P.); and Department of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit, De Boelelaan 1117, Amsterdam, the Netherlands (F.B.).

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http://dx.doi.org/10.1148/radiol.2019191146DOI Listing
August 2019

Early imaging predictors of long-term outcomes in relapse-onset multiple sclerosis.

Brain 2019 Aug;142(8):2276-2287

NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1093/brain/awz156DOI Listing
August 2019

Infratentorial and spinal cord lesions: Cumulative predictors of long-term disability?

Mult Scler 2019 Aug 2:1352458519864933. Epub 2019 Aug 2.

Department of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam, The Netherlands/Department of Diagnostic and Interventional Neuroradiology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1177/1352458519864933DOI Listing
August 2019

Longitudinal spinal cord atrophy in multiple sclerosis using the generalized boundary shift integral.

Ann Neurol 2019 Aug 6. Epub 2019 Aug 6.

Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, United Kingdom.

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http://dx.doi.org/10.1002/ana.25571DOI Listing
August 2019

Association between tumor location and neurocognitive functioning using tumor localization maps.

J Neurooncol 2019 Aug 13. Epub 2019 Aug 13.

Department of Medical Psychology and Brain Tumor Center, Amsterdam University Medical Center, Location VUmc, De Boelelaan 1118, 1081 HZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s11060-019-03259-zDOI Listing
August 2019

Associations of brain pathology, cognitive and physical markers with age in cognitively normal individuals aged 60-102 years.

J Gerontol A Biol Sci Med Sci 2019 Aug 14. Epub 2019 Aug 14.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/gerona/glz180DOI Listing
August 2019

Impact of white matter hyperintensity location on depressive symptoms in memory-clinic patients: a lesion–symptom mapping study

J Psychiatry Neurosci 2019 07;44(4):E1-E10

From the Alzheimer Centre Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands (Leeuwis, Hooghiemstra, Prins, Scheltens, van der Flier); the Department of Neurology, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht, the Netherlands (Weaver, Biesbroek, Exalto, Biessels); the Image Sciences Institute, University Medical Centre Utrecht, Utrecht, the Netherlands (Kuijf); the Department of Medical Humanities, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (Hooghiemstra); the Institutes of Neurology and Healthcare Engineering, UCL, London, United Kingdom (Barkhof); the Department of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (Barkhof); and the Department of Epidemiology & Biostatistics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (Flier).

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http://dx.doi.org/10.1503/jpn.180136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606429PMC
July 2019

and cortical superficial siderosis in CAA: Meta-analysis and potential mechanisms.

Neurology 2019 Jul 26;93(4):e358-e371. Epub 2019 Jun 26.

From the Hemorrhagic Stroke Research Program, Department of Neurology (A.C., M.P., A.B., M.E.G., J.N.G., J.R., S.M.G., A.V.), Massachusetts General Hospital Stroke Research Center, Harvard Medical School, Boston; Alzheimer Center and the Neuroscience Campus Amsterdam and Departments of Radiology and Nuclear Medicine (H.I.Z., F.B.), VU University Medical Center, the Netherlands; Karolinska Institutet (S.S., L.-O.W.), Karolinska University Hospital, Stockholm, Sweden; Department of Radiology (K.K., J.R.C.), Mayo Clinic, Rochester, MN; Department of Medicine (Neurology) (A.S.), McMaster University and Population Health Research Institute, Hamilton, Canada; Memory, Aging and Cognition Center (S.H., Y.L.C., J.R.C., C.C.), National University Health System, Singapore; Department of Pharmacology (S.H., Y.L.C., J.R.C., C.C.), National University of Singapore; Department of Nuclear Medicine and Centre for PET (P.A.Y.), The University of Melbourne, Parkville, Australia; Department of Neuroradiology (G.B.), Université Paris-Descartes, INSERM U894, CH Sainte-Anne, Paris, France; Department of Neurology and Neuroscience Center (H.K.N., D.L.N., S.W.S.), Samsung Medical Center, Seoul, Republic of Korea; UCL Institutes of Neurology and Healthcare Engineering (F.B.), London, UK; and Center for Genomic Medicine (J.R.) and Division of Neurocritical Care and Emergency Neurology (J.R.), Massachusetts General Hospital, Harvard Medical School, Boston.

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http://dx.doi.org/10.1212/WNL.0000000000007818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669935PMC
July 2019

Cognitive reserve and clinical progression in Alzheimer disease: A paradoxical relationship.

Neurology 2019 Jul 2;93(4):e334-e346. Epub 2019 Jul 2.

From Alzheimer Center Amsterdam, Department of Neurology (A.C.v.L., W.M.v.d.F., E.D., C.G., P.S., R.O.), and Department of Radiology and Nuclear Medicine (A.M.W., F.B., R.O.), Amsterdam Neuroscience, and Department of Epidemiology and Biostatistics (W.M.v.d.F., J.T.), Vrije Universiteit Amsterdam, Amsterdam UMC, the Netherlands; Institutes of Neurology and Healthcare Engineering (F.B.), University College London, UK; and Clinical Memory Research Unit (R.O.), Lund University, Sweden.

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http://dx.doi.org/10.1212/WNL.0000000000007821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669930PMC
July 2019

Improved performance of the 2017 McDonald criteria for diagnosis of multiple sclerosis in children in a real-life cohort.

Mult Scler 2019 Jul 18:1352458519863781. Epub 2019 Jul 18.

Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK/Department of Radiology and Nuclear Medicine, VU University Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458519863781DOI Listing
July 2019

Single-subject structural cortical networks in clinically isolated syndrome.

Mult Scler 2019 Jul 24:1352458519865739. Epub 2019 Jul 24.

Centre for Medical Image Computing (CMIC), UCL Medical Physics and Biomedical Engineering, University College London, London, UK/NIHR University College London Hospitals Biomedical Research Centre, London, UK/Alzheimer Center Amsterdam, Department of Neurology, Amsterdam University Medical Centers, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands/UCL Institute of Healthcare Engineering and UCL Queen Square Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1177/1352458519865739DOI Listing
July 2019

Erratum: Author Correction: High-dimensional detection of imaging response to treatment in multiple sclerosis.

NPJ Digit Med 2019;2:66. Epub 2019 Jul 16.

2Multiple Sclerosis Research Centre, NMR Research Unit, Department of Neuroinflammation, Queen Square Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1038/s41746-019-0144-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635413PMC
July 2019

Medial temporal lobe atrophy and posterior atrophy scales normative values.

Neuroimage Clin 2019 Jul 15;24:101936. Epub 2019 Jul 15.

LANVIE-Laboratory of Neuroimaging of Aging, University of Geneva, Geneva, Switzerland; LANE-Laboratory of Alzheimer's Neuroimaging and Epidemiology, IRCCS Istituto San Giovanni di Dio Fatebenefratelli, Brescia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2019.101936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690662PMC
July 2019

IDEAS becoming reality on the roadmap for biomarker validation in Alzheimer's disease.

Lancet Neurol 2019 Jun;18(6):519-520

UCL Institute of Neurology and UCL Institute of Healthcare Engineering, University College London, London, UK.

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http://dx.doi.org/10.1016/S1474-4422(19)30166-8DOI Listing
June 2019

High-dimensional detection of imaging response to treatment in multiple sclerosis.

NPJ Digit Med 2019 10;2:49. Epub 2019 Jun 10.

2Multiple Sclerosis Research Centre, NMR Research Unit, Department of Neuroinflammation, Queen Square Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1038/s41746-019-0127-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556513PMC
June 2019

Applying causal models to explore the mechanism of action of simvastatin in progressive multiple sclerosis.

Proc Natl Acad Sci U S A 2019 May 9;116(22):11020-11027. Epub 2019 May 9.

Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London WC1B 5EH, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1818978116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561162PMC
May 2019

A multi-shell multi-tissue diffusion study of brain connectivity in early multiple sclerosis.

Mult Scler 2019 May 10:1352458519845105. Epub 2019 May 10.

Queen Square MS Centre, Department of Neuroinflammation, UCL Institute of Neurology, University College London (UCL), London, UK/National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK.

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http://dx.doi.org/10.1177/1352458519845105DOI Listing
May 2019

Clinical relevance of acute cerebral microinfarcts in vascular cognitive impairment.

Neurology 2019 Apr 8;92(14):e1558-e1566. Epub 2019 Mar 8.

From the Department of Neurology (D.A.F., H.v.d.B., L.G.E., J.M.F.B., G.J.B.), Brain Center UMC Utrecht, University Medical Center Utrecht, Utrecht University; Department of Neurology (J.M.F.B.), Onze Lieve Vrouwe Gasthuis (OLVG) West; Department of Radiology & Nuclear Medicine (F.B.) Department of Neurology and Alzheimer Center Amsterdam (N.D.P., W.M.v.d.F.), Department of Epidemiology & Biostatistics (W.M.v.d.F.), Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, the Netherlands; and Institutes of Neurology and Healthcare Engineering (F.B.), University College London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000007250DOI Listing
April 2019

Impairment in complex activities of daily living is related to neurodegeneration in Alzheimer's disease-specific regions.

Neurobiol Aging 2019 03 26;75:109-116. Epub 2018 Nov 26.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands; Department of Epidemiology & Biostatistics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.11.018DOI Listing
March 2019

Reduced dynamics of functional connectivity and cognitive impairment in multiple sclerosis.

Mult Scler 2019 Mar 19:1352458519837707. Epub 2019 Mar 19.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1177/1352458519837707DOI Listing
March 2019

Modeling grey matter atrophy as a function of time, aging or cognitive decline show different anatomical patterns in Alzheimer's disease.

Neuroimage Clin 2019 19;22:101786. Epub 2019 Mar 19.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2019.101786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439228PMC
March 2019

Progressive brain rich-club network disruption from clinically isolated syndrome towards multiple sclerosis.

Neuroimage Clin 2018 28;19:232-239. Epub 2018 Mar 28.

Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; Tiantan Image Research Center, China National Clinical Research Center for Neurological Diseases, Beijing, China; Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China; Department of Radiology and Nuclear Medicine, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2018.03.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051763PMC
January 2019

Performance of PML diagnostic criteria in natalizumab-associated PML: data from the Dutch-Belgian cohort.

J Neurol Neurosurg Psychiatry 2019 Jan 12;90(1):44-46. Epub 2018 Aug 12.

Department of Radiology and Nuclear Medicine, Neuroscience Amsterdam, VUmc MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1136/jnnp-2018-318261DOI Listing
January 2019

Unraveling treatment response in multiple sclerosis: A clinical and MRI challenge.

Neurology 2019 Jan 26;92(4):180-192. Epub 2018 Dec 26.

From the Department of Neurosciences (C.G., L.P.), San Camillo-Forlanini Hospital, Rome, Italy; Centre d'Esclerosi Multiple de Catalunya (Cemcat), Department of Neurology/Neuroimmunology (M.T., J.R., J.S.-G., X.M.), and Magnetic Resonance Unit, Department of Radiology (A.R.), Hospital Universitari Vall d'Hebron, Universitat Autonoma de Barcelona, Spain; Biostatistics Unit (M.P.S.), Department of Health Sciences, University of Genoa; Neuroimaging Research Unit (M.F., M.A.R.), Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy; Nuffield Department of Clinical Neurosciences (J.P.), West Wing, John Radcliffe Hospital, Oxford; Institutes of Neurology & Healthcare Engineering (O.C., F.B.), University College London (O.C.), UK; Amsterdam Neuroscience and Department of Radiology and Nuclear Medicine (F.B., H.V.), VU University Medical Center, Amsterdam, the Netherlands; Department of Neurology (J.L.F.), Rigshospitalet Glostrup and University of Copenhagen, Denmark; Neuroradiological Academic Unit (T.A.Y.), Institute of Neurology, London, UK; Department of Neurology (C.E.), Medical University of Graz, Austria; Neurologic Clinic and Policlinic, Department of Medicine (L.K.), Clinical Research, Biomedicine and Biomedical Engineering, University Hospital Basel, University of Basel, Switzerland; Department of Neurology and Psychiatry (C.P.), Sapienza University, Rome; and Neurology and Neurometabolic Unit, Department of Neurological and Behavioral Sciences (N.D.S.), University of Siena, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000006810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345120PMC
January 2019

Exploring resting state connectivity in patients with psychotic depression.

PLoS One 2019 17;14(1):e0209908. Epub 2019 Jan 17.

Department of Old age Psychiatry, GGZ inGeest Specialized Mental Health Care and Amsterdam University Medical center, location VU University medical center (VUmc), Amsterdam, the Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0209908PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336266PMC
January 2019

Novel imaging phantom for accurate and robust measurement of brain atrophy rates using clinical MRI.

Neuroimage Clin 2019 4;21:101667. Epub 2019 Jan 4.

Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.nicl.2019.101667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350260PMC
January 2019

The Clinical Phenotype of Vascular Cognitive Impairment in Patients with Type 2 Diabetes Mellitus.

J Alzheimers Dis 2019 ;68(1):311-322

Department of Neurology, Brain Center Rudolph Magnus, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.3233/JAD-180914DOI Listing
January 2019

Atrophy subtypes in prodromal Alzheimer's disease are associated with cognitive decline.

Brain 2018 12;141(12):3443-3456

Alzheimer Center and Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/brain/awy264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669409PMC
December 2018

Slowly expanding/evolving lesions as a magnetic resonance imaging marker of chronic active multiple sclerosis lesions.

Mult Scler 2018 Dec 19:1352458518814117. Epub 2018 Dec 19.

NeuroRx Research, Montreal, QC, Canada/Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.1177/1352458518814117DOI Listing
December 2018

Mapping Deep Gray Matter Iron in Multiple Sclerosis by Using Quantitative Magnetic Susceptibility.

Radiology 2018 11 17;289(2):497-498. Epub 2018 Jul 17.

From the Department of Radiology & Nuclear Medicine, VU University Medical Center, De Boelelaan 1117, Amsterdam 1081 HV, the Netherlands (F.B.); and Department of Brain Repair and Rehabilitation (F.B., D.L.T.) and Leonard Wolfson Experimental Neurology Centre (D.L.T.), UCL Institute of Neurology, London, England.

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http://dx.doi.org/10.1148/radiol.2018181274DOI Listing
November 2018

Clinical phenotype, atrophy, and small vessel disease in ε2 carriers with Alzheimer disease.

Neurology 2018 11 19;91(20):e1851-e1859. Epub 2018 Oct 19.

From the Departments of Neurology and Alzheimer Center (C.G., P.S., W.M.v.d.F., R.O.), Radiology and Nuclear Medicine (C.G., F.B., B.N.M.v.B., R.O.), Neurochemistry Lab and Biobank (C.E.T.), and Clinical Chemistry, Epidemiology and Biostatistics (W.M.v.d.F.), VU University Medical Center, Neuroscience Campus Amsterdam, the Netherlands; Dementia Research Centre (C.H.S., S.O., M.J.C.), Department of Neurodegenerative Disease, UCL Institute of Neurology, Centre for Medical Image Computing (C.H.S., S.O., M.J.C.), and Institutes of Neurology & Healthcare Engineering (F.B.), University College London, UK; Department of Neurology (S.W.S.), Sungkyunkwan University School of Medicine, and Neuroscience Center (S.W.S.), Samsung Medical Center; Department of Clinical Research Design & Evaluation (S.W.S.), SAIHST, Sungkyunkwan University, Seoul, Korea; and Clinical Memory Research Unit (R.O.), Lund University, Sweden.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000006503DOI Listing
November 2018

The hippocampus in multiple sclerosis.

Lancet Neurol 2018 10 18;17(10):918-926. Epub 2018 Sep 18.

Neuroimaging Research Unit and Department of Neurology, Institute of Experimental Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(18)30309-0DOI Listing
October 2018

Inclusion of optic nerve involvement in dissemination in space criteria for multiple sclerosis.

Neurology 2018 09 17;91(12):e1130-e1134. Epub 2018 Aug 17.

From the Queen Square Multiple Sclerosis Centre (W.J.B., C.T., D.H.M., O.C.), Department of Neuroinflammation, UCL Institute of Neurology; Lysholm Department of Neuroradiology (K.A.M., F.B.), National Hospital for Neurology and Neurosurgery; UCL Institute of Healthcare Engineering (F.B.), London, UK; Department of Radiology and Nuclear Medicine (F.B.), VU University Medical Centre, Amsterdam, the Netherlands; and NIHR University College London Hospitals Biomedical Research Centre (F.B., O.C.), UK.

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http://dx.doi.org/10.1212/WNL.0000000000006207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161554PMC
September 2018

Predicting cognitive decline in multiple sclerosis: a 5-year follow-up study.

Brain 2018 09;141(9):2605-2618

Department of Anatomy and Neurosciences, Amsterdam Neuroscience, MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/brain/awy202DOI Listing
September 2018

Correction to: A phase III randomized trial of gantenerumab in prodromal Alzheimer's disease.

Alzheimers Res Ther 2018 09 27;10(1):99. Epub 2018 Sep 27.

Clinical Pharmacology and Bioanalytical R&D, Pharmaceutical Sciences, Roche Pharma Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland.

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http://dx.doi.org/10.1186/s13195-018-0409-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158837PMC
September 2018

Subjective Cognitive Impairment Cohort (SCIENCe): study design and first results.

Alzheimers Res Ther 2018 08 7;10(1):76. Epub 2018 Aug 7.

Alzheimer Center and Department of Neurology, Amsterdam Neuroscience, Amsterdam University Medical Centers, Vrije Universiteit, De Boelelaan 1118, 1081 HZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/s13195-018-0390-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080529PMC
August 2018

Three-Tesla MRI does not improve the diagnosis of multiple sclerosis: A multicenter study.

Neurology 2018 07 20;91(3):e249-e257. Epub 2018 Jun 20.

From the Departments of Neurology (M.H.J.H., J.B., J.K.) and Radiology and Nuclear Medicine (I.D.K., M.L.d.V., M.P.W., F.B.), MS Centre Amsterdam, and Department of Epidemiology and Biostatistics (B.I.L.-W.), VU University Medical Centre; Department of Radiology and Nuclear Medicine (I.D.K.), Onze Lieve Vrouwen Gasthuis, Amsterdam, the Netherlands; Queen Square Multiple Sclerosis Centre (N.C., O.C.) and Institutes of Neurology & Healthcare Engineering (F.B.), UCL Institute of Neurology, London, UK; Department of Neurology and Psychiatry (E.S., P.P.), Sapienza University of Rome, Italy; Department of Neurology (M. Andelova, M. Amann) and Division of Neuroradiology, Department of Radiology (M. Amann, J.M.L.), University Hospital Basel; Medical Image Analysis Centre (M. Amann), Basel, Switzerland; Istituto Neurologico Mediterraneo (P.P.), Neuromed, Pozzilli (IS), Italy; Department of Neurology (C.O.-G.), Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain; National Institute for Health Research (O.C., F.B.), University College London Hospitals (UCLH) Biomedical Research Centre (BRC), UK; Department of Neurosciences (C.G.), San Camillo-Forlanini Hospital, Rome, Italy; and Department of Diagnostic and Interventional Radiology and Nuclear Medicine (C.L.), St. Josef Hospital, Ruhr University, Bochum, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000005825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059032PMC
July 2018

Spinal cord atrophy rates: Ready for prime time in multiple sclerosis clinical trials?

Neurology 2018 07 27;91(4):157-158. Epub 2018 Jun 27.

From the Centre for Medical Image Computing (CMIC) (F.P., F.B.), Department of Medical Physics and Bioengineering, University College London; UCL Institute of Neurology (F.P., F.B.), London, UK; and Department of Radiology and Nuclear Medicine (F.B.), VU University Medical Centre, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1212/WNL.0000000000005873DOI Listing
July 2018

Disclosure of amyloid positron emission tomography results to individuals without dementia: a systematic review.

Alzheimers Res Ther 2018 07 28;10(1):72. Epub 2018 Jul 28.

Department of Neurology & Alzheimer Center, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/s13195-018-0398-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064628PMC
July 2018

Microbleeds are associated with depressive symptoms in Alzheimer's disease.

Alzheimers Dement (Amst) 2018 6;10:112-120. Epub 2017 Dec 6.

Alzheimer Center and Department of Neurology, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.dadm.2017.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956804PMC
December 2017