Publications by authors named "Frederik Barkhof"

98Publications

Cerebral effects of GLP-1 receptor blockade before and after Roux-en-Y Gastric Bypass in obese women: a proof-of-concept resting-state fMRI study.

Diabetes Obes Metab 2020 Oct 20. Epub 2020 Oct 20.

Amsterdam Diabetes Center / Department of Internal Medicine, Amsterdam University Medical Centers, Vrije Universiteit, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/dom.14233DOI Listing
October 2020

Brain structural and functional alterations in MOG antibody disease.

Mult Scler 2020 Oct 15:1352458520964415. Epub 2020 Oct 15.

Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, P.R. China/Tiantan Image Research Center, China National Clinical Research Center for Neurological Diseases, Beijing, P.R. China.

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http://dx.doi.org/10.1177/1352458520964415DOI Listing
October 2020

Mild progressive multifocal leukoencephalopathy after switching from natalizumab to ocrelizumab.

Neurol Neuroimmunol Neuroinflamm 2021 Jan 13;8(1). Epub 2020 Oct 13.

From the Department of Neurology (A.A.T., Z.Y.G.L., E.E.M.S., B.A.J., Z.L.E.K., J.K.), Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, MS Center Amsterdam; Department of Clinical Chemistry (C.E.T.), Neurochemistry Laboratory and Biobank, Amsterdam Neuroscience, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam; Department of Ophthalmology (A.P.), Neuro-ophthalmology Expertise Center, Amsterdam Neuroscience, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands; Department of Diagnostic and Interventional Neuroradiology (M.P.W.), Hanover Medical School, Hanover, Germany; Department of Radiology and Nuclear Medicine (M.P.W., F.B.), Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, MS Center Amsterdam, the Netherlands; Department of Neuroinflammation (F.B.), Queen Square MS Centre, UCL Institute of Neurology, Faculty of Brain Sciences, University College London; and National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre (F.B.), London, United Kingdom.

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http://dx.doi.org/10.1212/NXI.0000000000000904DOI Listing
January 2021

In vivo imaging of chronic active lesions in multiple sclerosis.

Mult Scler 2020 Sep 23:1352458520958589. Epub 2020 Sep 23.

Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, University College London, London, UK/Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London, London, UK/Radiology & Nuclear Medicine, VU University Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458520958589DOI Listing
September 2020

Spinal cord atrophy in a primary progressive multiple sclerosis trial: Improved sample size using GBSI.

Neuroimage Clin 2020 Sep 9;28:102418. Epub 2020 Sep 9.

Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, United Kingdom; National Institute for Health Research, University College London Hospitals Biomedical Research Centre, London, United Kingdom; Centre for Medical Image Computing, Department of Medical Physics and Bioengineering, University College London, London, United Kingdom; Open University of Catalonia, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.nicl.2020.102418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7509079PMC
September 2020

Can MRI be used as a proxy for ? A case study.

Brain Commun 2019 24;1(1):fcz030. Epub 2019 Oct 24.

Department of Anatomy and Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/braincomms/fcz030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425311PMC
October 2019

Pathological correlates of the magnetization transfer ratio in multiple sclerosis.

Neurology 2020 Sep 16. Epub 2020 Sep 16.

Queen Square MS Centre, NMR Research Unit, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, United Kingdom

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http://dx.doi.org/10.1212/WNL.0000000000010909DOI Listing
September 2020

What determines cognitive functioning in the oldest-old? The EMIF-AD 90+ Study.

J Gerontol B Psychol Sci Soc Sci 2020 Sep 8. Epub 2020 Sep 8.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/geronb/gbaa152DOI Listing
September 2020

Histopathology-validated recommendations for cortical lesion imaging in multiple sclerosis.

Brain 2020 Aug 21. Epub 2020 Aug 21.

Department of Anatomy and Neurosciences, MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/brain/awaa233DOI Listing
August 2020

Sex differences in memory clinic patients with possible vascular cognitive impairment.

Alzheimers Dement (Amst) 2020 25;12(1):e12090. Epub 2020 Aug 25.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience Vrije Universiteit Amsterdam, Amsterdam UMC Amsterdam the Netherlands.

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http://dx.doi.org/10.1002/dad2.12090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447910PMC
August 2020

A clinical-radiological framework of the right temporal variant of frontotemporal dementia.

Brain 2020 Sep;143(9):2831-2843

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/brain/awaa225DOI Listing
September 2020

Immune signatures of prodromal multiple sclerosis in monozygotic twins.

Proc Natl Acad Sci U S A 2020 09 17;117(35):21546-21556. Epub 2020 Aug 17.

Department of Neurology with Institute of Translational Neurology, University Hospital Münster, Albert-Schweitzer Campus 1, 48149 Münster, Germany;

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http://dx.doi.org/10.1073/pnas.2003339117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474627PMC
September 2020

The relation between APOE genotype and cerebral microbleeds in cognitively unimpaired middle- and old-aged individuals.

Neurobiol Aging 2020 Jun 29;95:104-114. Epub 2020 Jun 29.

Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands; Institutes of Neurology and Healthcare Engineering, UCL, London, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2020.06.015DOI Listing
June 2020

Prediction of poor clinical outcome in vascular cognitive impairment: TRACE-VCI study.

Alzheimers Dement (Amst) 2020 10;12(1):e12077. Epub 2020 Aug 10.

Department of Neurology and Neurosurgery UMC Utrecht Brain Center University Medical Center Utrecht Utrecht Universiteit Utrecht the Netherlands.

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http://dx.doi.org/10.1002/dad2.12077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416669PMC
August 2020

Sex differences in CSF biomarkers vary by Alzheimer's disease stage and APOE ε4 genotype.

Neurology 2020 Aug 11. Epub 2020 Aug 11.

Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry, Amsterdam Neuroscience, Amsterdam UMC, VU University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1212/WNL.0000000000010629DOI Listing
August 2020

Wearable technologies to measure clinical outcomes in multiple sclerosis: A scoping review.

Mult Scler 2020 Aug 4:1352458520946005. Epub 2020 Aug 4.

Queen Square MS Centre and Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK/National Institute for Health Research (NIHR), Biomedical Research Centre, University College London Hospitals (UCLH), London, UK/MRC CTU at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK.

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http://dx.doi.org/10.1177/1352458520946005DOI Listing
August 2020

Small vessel disease lesion type and brain atrophy: The role of co-occurring amyloid.

Alzheimers Dement (Amst) 2020 13;12(1):e12060. Epub 2020 Jul 13.

Department of Neurology and Neurosurgery UMC Utrecht Brain Center Utrecht University Utrecht the Netherlands.

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http://dx.doi.org/10.1002/dad2.12060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7364862PMC
July 2020

Personalized extended interval dosing of natalizumab in MS: A prospective multicenter trial.

Neurology 2020 08 20;95(6):e745-e754. Epub 2020 Jul 20.

From the Department of Neurology, Amsterdam MS Center (Z.L.E.v.K., B.W.v.O., B.M.J.U., J.K.), Department of Radiology (M.P.W., F.B.), and Neurochemistry Lab and Biobank, Department of Clinical Chemistry (C.E.T.), Amsterdam Neuroscience, and Department of Epidemiology and Biostatistics (B.I.L.-W.), Amsterdam University Medical Centers, Vrije Universiteit; Department of Neurology (E.L.J.H.), St. Antonius Hospital, Utrecht, the Netherlands; Department of Diagnostic and Interventional Neuroradiology (M.P.W.), Hannover Medical School, Germany; Department of Neurology (N.F.K.), OLVG Hospital, Amsterdam; Department of Neurology (J.P.M.), Rijnstate Hospital, Arnhem; Biologics Lab, Bioanalysis (A.d.V.), Sanquin Diagnostic Services; Department of Immunopathology (A.t.B., T.R.), Sanquin Research, Amsterdam; Landsteiner Laboratory (A.t.B., T.R.), Academic Medical Centre, University of Amsterdam, the Netherlands; and UCL Institutes of Neurology & Healthcare Engineering (F.B.), Queen Square, London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000009995DOI Listing
August 2020

Multitracer model for staging cortical amyloid deposition using PET imaging.

Neurology 2020 09 16;95(11):e1538-e1553. Epub 2020 Jul 16.

From Department of Radiology and Nuclear Medicine (L.E.C., F.H., S.I., M.Y., S.S.V.G., V.W., A.M.W., A.A.L., R.B., B.N.M.v.B., F.B., I.L.A.), Neurochemistry Laboratory (C.E.T.), Alzheimer Center (D.A., A.d.W., E.K., M.v.B., P.J.V., P.S., W.M.v.d.F.), and Department of Neurology (D.A., A.d.W., E.K., M.v.B., P.J.V., P.S., W.M.v.d.F.), Amsterdam UMC, Vrije Universiteit Amsterdam, Netherlands; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation (G.S., J.L.M., J.D.G.), Barcelona; Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (J.D.G.); Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (J.L.M.), Madrid; IMIM (Hospital del Mar Medical Research Institute) (G.S., J.L.M., J.D.G.), Barcelona; Universitat Pompeu Fabra (J.L.M., J.D.G.), Barcelona, Spain; Laboratory of Neuroimaging of Aging (D.A.), University of Geneva; Memory Clinic (D.A.), University Hospital of Geneva, Switzerland; Centre for Medical Image Computing (P.M., F.B.), Medical Physics and Biomedical Engineering, University College London, London, UK; and Janssen Pharmaceutica NV (M.E.S.), Beerse, Belgium.

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http://dx.doi.org/10.1212/WNL.0000000000010256DOI Listing
September 2020

Latent atrophy factors related to phenotypical variants of posterior cortical atrophy.

Neurology 2020 Sep 16;95(12):e1672-e1685. Epub 2020 Jul 16.

From the Department of Neurology and Alzheimer Center (C.G., Y.A.L.P., P.S., W.M.v.d.F., R.O.), and Departments of Radiology and Nuclear Medicine (F.B.) and Epidemiology and Biostatistics (W.M.v.d.F.), Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, the Netherlands; Department of Electrical and Computer Engineering (B.T.T.Y., X.Z., N.S.), Clinical Imaging Research Centre, N1 Institute for Health and Memory Networks Program, National University of Singapore; Montreal Neurological Institute (J.W.V.), McGill University, Montreal, Canada; Computer Science and Artificial Intelligence Laboratory (X.Z.), Massachusetts Institute of Technology, Cambridge; Department of Neurology and Neurological Sciences (E.C.M.), Stanford University, CA; Departments of Neurology, Radiology and Biomedical Imaging (B.L.M., H.J.R., R.L.J., G.D.R.), University of California, San Francisco; Institutes of Neurology & Healthcare Engineering (F.B.), University College London, UK; and Clinical Memory Research Unit (R.O.), Lund University, Sweden.

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http://dx.doi.org/10.1212/WNL.0000000000010362DOI Listing
September 2020

Relationship between β-amyloid and structural network topology in decedents without dementia.

Neurology 2020 08 13;95(5):e532-e544. Epub 2020 Jul 13.

From the Departments of Anatomy and Neurosciences (L.E.J., M.D.S., N.B., J.J.G.G., L.D., W.D.J.v.d.B.), Pathology (A.J.M.R.), and Radiology and Nuclear Medicine (F.B.), Amsterdam UMC, Vrije Universiteit Amsterdam, the Netherlands; and Institutes of Neurology and Healthcare Engineering (F.B.), University College London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000009910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455348PMC
August 2020

A randomized, placebo-controlled, phase 2 trial of laquinimod in primary progressive multiple sclerosis.

Neurology 2020 08 10;95(8):e1027-e1040. Epub 2020 Jul 10.

From Barts and The London School of Medicine and Dentistry (G.G.), Blizard Institute, Queen Mary University of London, UK; Teva Pharmaceuticals R&D (V.K.), Teva Pharmaceutical Industries (T.L.), Great Valley, PA; Department of Neurology, Medical Faculty (V.K., H.-P.H.), Heinrich-Heine Universität Düsseldorf, Germany; Teva Pharmaceutical Industries (J.R.S., A.P.T.), Malvern, PA; Corinne Goldsmith Dickinson Center for Multiple Sclerosis (S.K.) and Neurology (F.L.), Icahn School of Medicine at Mount Sinai, New York, NY; Departments of Neuroscience, Rehabilitation, Ophthalmology, Genetics, and Maternal and Child Health and Center of Excellence for Biomedical Research (A.U.) and Department of Health Sciences (M.P.S.), University of Genoa; Ospedale Policlinico San Martino-IRCCS (A.U.), Genoa, Italy; Department of Neurology (B.M.J.U.), MS Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, the Netherlands; Division of Neurology (X.M.), University of Toronto/MS Centre St Michael's Hospital, Canada; Neurology-Neuroimmunology Department and Neurorehabilitation Unit (X.M.), Multiple Sclerosis Centre of Catalonia; Department of Neurology (X.M.), Hospital Universitari de la Vall d'Hebron, Barcelona, Spain; Weill Institute for Neurosciences (B.A.C.C.), Department of Neurology, University of California San Francisco; Radiology & Nuclear Medicine (F.L.), VU University Medical Center, Amsterdam, the Netherlands; and UCL Institutes of Neurology and Healthcare Engineering (F.B.), London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000010284DOI Listing
August 2020

Single-subject gray matter networks predict future cortical atrophy in preclinical Alzheimer's disease.

Neurobiol Aging 2020 Oct 21;94:71-80. Epub 2020 May 21.

Department of Neurology, Alzheimer Center Amsterdam, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.neurobiolaging.2020.05.008DOI Listing
October 2020

Using Unsupervised Learning to Identify Clinical Subtypes of Alzheimer's Disease in Electronic Health Records.

Stud Health Technol Inform 2020 Jun;270:499-503

Institute of Health Informatics, University College London, London, UK.

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http://dx.doi.org/10.3233/SHTI200210DOI Listing
June 2020

Clinico-radiological dissociation of disease activity in MS patients: frequency and clinical relevance.

J Neurol 2020 Jun 20. Epub 2020 Jun 20.

Department of Radiology and Nuclear Medicine, Amsterdam UMC, Location VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00415-020-09991-1DOI Listing
June 2020

ATN classification and clinical progression in subjective cognitive decline: The SCIENCe project.

Neurology 2020 07 10;95(1):e46-e58. Epub 2020 Jun 10.

From the Alzheimer Center, Department of Neurology (J.L.E., T.T., L.M.P.W., I.M.W.V., R.E.R.S., A.C.v.H., K.A.v.d.B., M.v.L., J.T., A.d.B., P.J.V., N.D.P., S.A.M.S., P.S., B.N.M.v.B., W.M.v.d.F.), and Department of Radiology & Nuclear Medicine (S.C.J.V., F.B., B.N.v.B.), Amsterdam Neuroscience, Neurochemistry Laboratory, Department of Clinical Chemistry (I.M.W.V., C.E.T.), and Department of Epidemiology & Biostatistics (W.M.v.d.F.), Vrije Universiteit Amsterdam, Amsterdam UMC, the Netherlands; UCL Institutes of Neurology and Healthcare Engineering (F.B.), London, UK; Department of Biological Psychology (A.d.B.), Neuroscience Amsterdam, VU University Amsterdam; Alzheimer Center Limburg (P.J.V.), School for Mental Health and Neuroscience, Maastricht University, the Netherlands; and Department of Neurobiology, Care Sciences and Society (P.J.V.), Division of Neurogeriatrics, Karolinska Institutet, Stockholm Sweden.

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http://dx.doi.org/10.1212/WNL.0000000000009724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7371376PMC
July 2020

MS-SMART study: systematic sampling bias concerns - Authors' reply.

Lancet Neurol 2020 06 26;19(6):479-480. Epub 2020 May 26.

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1016/S1474-4422(20)30149-6DOI Listing
June 2020

Response: Brain miliary enhancement.

Neuroradiology 2020 May 25;62(5):547. Epub 2020 Mar 25.

Department of Radiology and Nuclear Medicine, Amsterdam UMC Location VUmc, P.O. Box 7057, 1007, MB, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00234-020-02404-0DOI Listing
May 2020

Prodromal Dementia With Lewy Bodies: Clinical Characterization and Predictors of Progression.

Mov Disord 2020 05 11;35(5):859-867. Epub 2020 Feb 11.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam University Medical Centers, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1002/mds.27997DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317511PMC
May 2020

Ongoing microstructural changes in the cervical cord underpin disability progression in early primary progressive multiple sclerosis.

Mult Scler 2020 Jan 21:1352458519900971. Epub 2020 Jan 21.

Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, University College London, London, UK/Biomedical Research Centre, University College London Hospitals (UCLH), National Institute for Health Research (NIHR), London, UK.

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http://dx.doi.org/10.1177/1352458519900971DOI Listing
January 2020

Brain miliary enhancement.

Neuroradiology 2020 Mar 10;62(3):283-300. Epub 2020 Jan 10.

Department of Radiology and Nuclear Medicine, Amsterdam UMC, Location VUmc, P.O. Box 7057, 1007, MB, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00234-019-02335-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044143PMC
March 2020

Methylphenidate and galantamine in patients with vascular cognitive impairment-the proof-of-principle study STREAM-VCI.

Alzheimers Res Ther 2020 01 7;12(1):10. Epub 2020 Jan 7.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, VU University Medical Center, Amsterdam UMC, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/s13195-019-0567-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947990PMC
January 2020

Generalised boundary shift integral for longitudinal assessment of spinal cord atrophy.

Neuroimage 2020 04 24;209:116489. Epub 2019 Dec 24.

NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, Russell Square, London, WC1B 5EH, UK; Brain MRI 3T , UKCenter, IRCCS Mondino Foundation, Pavia, Italy; Department of Brain and Behavioural Sciences, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1016/j.neuroimage.2019.116489DOI Listing
April 2020

PET and CSF amyloid-β status are differently predicted by patient features: information from discordant cases.

Alzheimers Res Ther 2019 12 7;11(1):100. Epub 2019 Dec 7.

Department of Neurology & Alzheimer Center Amsterdam, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/s13195-019-0561-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898919PMC
December 2019

Why Is Amyloid-β PET Requested After Performing CSF Biomarkers?

J Alzheimers Dis 2020 ;73(2):559-569

Department of Neurology & Alzheimer Center Amsterdam, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.

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http://dx.doi.org/10.3233/JAD-190836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081099PMC
January 2020

Comorbid amyloid-β pathology affects clinical and imaging features in VCD.

Alzheimers Dement 2020 02 4;16(2):354-364. Epub 2020 Jan 4.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jalz.2019.08.190DOI Listing
February 2020

Prion disease diagnosis using subject-specific imaging biomarkers within a multi-kernel Gaussian process.

Neuroimage Clin 2019 25;24:102051. Epub 2019 Oct 25.

Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom; School of Biomedical Engineering & Imaging Sciences, King's College London, King's Health Partners, St Thomas' Hospital, London, SE1 7EH, United Kingdom.

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http://dx.doi.org/10.1016/j.nicl.2019.102051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978211PMC
September 2020

SVM recursive feature elimination analyses of structural brain MRI predicts near-term relapses in patients with clinically isolated syndromes suggestive of multiple sclerosis.

Neuroimage Clin 2019 22;24:102011. Epub 2019 Oct 22.

Queen Square MS Centre, University College London, London, United Kingdom; National Institute of Health Research (NIHR), University College London Hospitals, Biomedical Research Centre, London, United Kingdom.

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http://dx.doi.org/10.1016/j.nicl.2019.102011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861587PMC
September 2020

A 30-Year Clinical and Magnetic Resonance Imaging Observational Study of Multiple Sclerosis and Clinically Isolated Syndromes.

Ann Neurol 2020 01 22;87(1):63-74. Epub 2019 Nov 22.

Nuclear Magnetic Resonance Research Unit, Queen Square Multiple Sclerosis Centre, University College London Institute of Neurology, London, United Kingdom.

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http://dx.doi.org/10.1002/ana.25637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973080PMC
January 2020

Exploring effects of Souvenaid on cerebral glucose metabolism in Alzheimer's disease.

Alzheimers Dement (N Y) 2019 27;5:492-500. Epub 2019 Sep 27.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.trci.2019.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804721PMC
September 2019

Clinically relevant cranio-caudal patterns of cervical cord atrophy evolution in MS.

Neurology 2019 11 14;93(20):e1852-e1866. Epub 2019 Oct 14.

From the Neuroimaging Research Unit (M.A.R., P.V., A.M., P.P., M.F.) and Neurology Unit (M.A.R., P.P., G.C., M.F.), Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy; Department of Neurology (C.G., C.Z.), Neurocenter of Southern Switzerland, Regional Hospital Lugano (EOC), Lugano; Faculty of Biomedical Sciences (C.G., C.Z.), Università della Svizzera Italiana, Lugano, Switzerland; Section of Neuroradiology and MRI Unit, Department of Radiology (A.R.), and Department of Neurology/Neuroimmunology (X.M.), Multiple Sclerosis Centre of Catalonia, Hospital Universitari Vall d'Hebron, Barcelona, Spain; NMR Research Unit (H.K., O.C.), Queen Square MS Centre, Department of Neuroinflammation, UCL Institute of Neurology, London; Nuffield Department of Clinical Neurosciences (L.M., J.P.), University of Oxford, UK; Department of Advanced Medical and Surgical Sciences, and 3T MRI Center, (A.G., A.B.), University of Campania "Luigi Vanvitelli," Naples, Italy; Department of Neurology (A.G., P.E.), Universitätsmedizin Mannheim, University of Heidelberg, Germany; Department of Radiology and Nuclear Medicine (C.L., B.B.) and Institute of Neuroradiology (C.L., B.B.), St. Josef Hospital, Ruhr-University Bochum, Germany; Department of Radiology and Nuclear Medicine (F.B., H.V.), MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, location VUmc, the Netherlands; Institutes of Neurology and Healthcare Engineering (F.B.), University College London, UK; and Vita-Salute San Raffaele University (P.P., G.C., M.F.), Milan, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000008466DOI Listing
November 2019

Applying the ATN scheme in a memory clinic population: The ABIDE project.

Neurology 2019 10 9;93(17):e1635-e1646. Epub 2019 Oct 9.

From the Alzheimer Center Amsterdam, Department of Neurology (D.A., A.d.W., R.O., W.P., F.B., C.G., I.v.M., M.Z., B.N.v.B., P.S., W.M.v.d.F.), Department of Radiology & Nuclear Medicine (R.O., C.G., M.Y., F.B., B.N.v.B.), and Neurochemistry Laboratory, Department of Clinical Chemistry (C.E.T.), Amsterdam Neuroscience, and Department of Epidemiology & Biostatistics (I.v.M., W.M.v.d.F.), Vrije Universiteit Amsterdam, Amsterdam UMC, the Netherlands; Laboratory of Neuroimaging of Aging (LANVIE) (D.A., G.B.F.), University of Geneva, Switzerland; Memory Clinic (D.A.), University Hospitals of Geneva, Switzerland; Laboratory of Alzheimer's Neuroimaging and Epidemiology (LANE) (D.A.), Saint John of God Clinical Research Centre; Department of Molecular and Translational Medicine (D.A.), University of Brescia, Italy; Clinical Memory Research Unit (R.O.), Lund University, Malmö, Sweden; Institutes of Neurology and Healthcare Engineering (F.B.), UCL, London, UK; and Memory Clinic (D.A., G.B.F.), University Hospitals of Geneva, Switzerland.

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http://dx.doi.org/10.1212/WNL.0000000000008361DOI Listing
October 2019

Randomized trial of daily high-dose vitamin D in patients with RRMS receiving subcutaneous interferon β-1a.

Neurology 2019 11 8;93(20):e1906-e1916. Epub 2019 Oct 8.

From the Department of Neurology (R.H., J.S.,), Zuyderland Medical Centre Sittard, Maastricht University Medical Centre; Department of Neurology (J.S.), Canisius Wilhelmina Ziekenhuis, Nijmegen, the Netherlands; Department of Nutritional Sciences (R.V.), University of Toronto, Canada; Akershus University Hospital and University of Oslo (T.H.), Norway; Merck GmbH (K.M.), Vienna, Austria; Service de Neurologie (M.S.), Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland; Departments of Neurology (J.K.) and Radiology and Nuclear Medicine (F.B.), VU University Medical Centre, Amsterdam, the Netherlands; Institutes of Neurology and Healthcare Engineering (F.B.), University College London, UK; Independent Consultant (M.B.), Krailling, Germany; and U.O.C. Neurologia and Multiple Sclerosis Center (L.M.E.G.), Fondazione Istituto G. Giglio di Cefalù, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000008445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946471PMC
November 2019

Assessment of the appropriate use criteria for amyloid PET in an unselected memory clinic cohort: The ABIDE project.

Alzheimers Dement 2019 11 6;15(11):1458-1467. Epub 2019 Oct 6.

Department of Neurology, Amsterdam Neuroscience, Alzheimer Center, VU University, Amsterdam UMC, Amsterdam, the Netherlands; Department of Epidemiology and Biostatistics, Amsterdam Neuroscience, VU University of Amsterdam, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.jalz.2019.07.003DOI Listing
November 2019

Cerebral amyloid burden is associated with white matter hyperintensity location in specific posterior white matter regions.

Neurobiol Aging 2019 12 9;84:225-234. Epub 2019 Aug 9.

Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, the Netherlands.

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.08.001DOI Listing
December 2019

Cortical atrophy accelerates as cognitive decline worsens in multiple sclerosis.

Neurology 2019 10 4;93(14):e1348-e1359. Epub 2019 Sep 4.

From the Departments of Anatomy & Neurosciences (A.J.C.E., M.D.S., K.A.M., H.E.H., M.M.S., J.J.G.G.), Radiology and Nuclear Medicine (I.D., J.W.P., F.B., H.V.), and Neurology (I.D., B.M.J.U.), Amsterdam Neuroscience, MS Center Amsterdam, Amsterdam UMC, Location VUmc, the Netherlands; and Institutes of Neurology and Healthcare Engineering (F.B.), UCL, London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000008198DOI Listing
October 2019

Onset of clinical and MRI efficacy of ocrelizumab in relapsing multiple sclerosis.

Neurology 2019 11 4;93(19):e1778-e1786. Epub 2019 Sep 4.

From the Department of Radiology and Nuclear Medicine (F.B.), VU University Medical Centre, Amsterdam, the Netherlands; UCL Institutes of Healthcare Engineering and Neurology (F.B.), London, UK; Neurologic Clinic and Policlinic, Departments of Medicine, Clinical Research, Biomedicine and Biomedical Engineering (L.K.), University Hospital Basel, University of Basel, Switzerland; Department of Neurology (J.S.W.), McGovern Medical School, UTHealth, Houston, TX; Department of Radiology (D.K.B.L.), University of British Columbia, Vancouver, Canada; Department of Neurology and Center for Neuroinflammation and Experimental Therapeutics (A.B.-O.), University of Pennsylvania, Philadelphia; Department of Neurology, Medical Faculty (H.-P.H.), Heinrich-Heine University Düsseldorf, Germany; F. Hoffmann-La Roche Ltd. (S.B., A.S., J.N., H.K.), Basel, Switzerland; Genentech, Inc. (J.H., L.J.), South San Francisco; and Department of Neurology (S.L.H.), University of California, San Francisco. During completion of the work related to this article, S. Belachew was an employee of F. Hoffmann-La Roche Ltd.; his current affiliation is Biogen, Cambridge, MA.

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http://dx.doi.org/10.1212/WNL.0000000000008189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946481PMC
November 2019

Association between tumor location and neurocognitive functioning using tumor localization maps.

J Neurooncol 2019 Sep 13;144(3):573-582. Epub 2019 Aug 13.

Department of Medical Psychology and Brain Tumor Center, Amsterdam University Medical Center, Location VUmc, De Boelelaan 1118, 1081 HZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s11060-019-03259-zDOI Listing
September 2019

Longitudinal spinal cord atrophy in multiple sclerosis using the generalized boundary shift integral.

Ann Neurol 2019 11 22;86(5):704-713. Epub 2019 Aug 22.

Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, United Kingdom.

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http://dx.doi.org/10.1002/ana.25571DOI Listing
November 2019

Medial temporal lobe atrophy and posterior atrophy scales normative values.

Neuroimage Clin 2019 15;24:101936. Epub 2019 Jul 15.

LANVIE-Laboratory of Neuroimaging of Aging, University of Geneva, Geneva, Switzerland; LANE-Laboratory of Alzheimer's Neuroimaging and Epidemiology, IRCCS Istituto San Giovanni di Dio Fatebenefratelli, Brescia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2019.101936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690662PMC
September 2020

Infratentorial and spinal cord lesions: Cumulative predictors of long-term disability?

Mult Scler 2020 Oct 2;26(11):1381-1391. Epub 2019 Aug 2.

Department of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam, The Netherlands/Department of Diagnostic and Interventional Neuroradiology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1177/1352458519864933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543019PMC
October 2020

The quantitative neuroradiology initiative framework: application to dementia.

Br J Radiol 2019 Sep 1;92(1101):20190365. Epub 2019 Aug 1.

1Centre for Medical Image Computing (CMIC), Department of Medical Physics and Bioengineering, University College London, London, United Kingdom.

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http://dx.doi.org/10.1259/bjr.20190365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732931PMC
September 2019

Early imaging predictors of long-term outcomes in relapse-onset multiple sclerosis.

Brain 2019 08;142(8):2276-2287

NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1093/brain/awz156DOI Listing
August 2019

Erratum: Author Correction: High-dimensional detection of imaging response to treatment in multiple sclerosis.

NPJ Digit Med 2019;2:66. Epub 2019 Jul 16.

2Multiple Sclerosis Research Centre, NMR Research Unit, Department of Neuroinflammation, Queen Square Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1038/s41746-019-0144-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635413PMC
July 2019

Single-subject structural cortical networks in clinically isolated syndrome.

Mult Scler 2020 Oct 24;26(11):1392-1401. Epub 2019 Jul 24.

Centre for Medical Image Computing (CMIC), UCL Medical Physics and Biomedical Engineering, University College London, London, UK/NIHR University College London Hospitals Biomedical Research Centre, London, UK/Alzheimer Center Amsterdam, Department of Neurology, Amsterdam University Medical Centers, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands/UCL Institute of Healthcare Engineering and UCL Queen Square Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1177/1352458519865739DOI Listing
October 2020

Improved performance of the 2017 McDonald criteria for diagnosis of multiple sclerosis in children in a real-life cohort.

Mult Scler 2020 Oct 18;26(11):1372-1380. Epub 2019 Jul 18.

Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK/Department of Radiology and Nuclear Medicine, VU University Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1177/1352458519863781DOI Listing
October 2020

High-dimensional detection of imaging response to treatment in multiple sclerosis.

NPJ Digit Med 2019 10;2:49. Epub 2019 Jun 10.

2Multiple Sclerosis Research Centre, NMR Research Unit, Department of Neuroinflammation, Queen Square Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1038/s41746-019-0127-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556513PMC
June 2019