Publications by authors named "Frederick W Miller"

100Publications

Anti-MDA5 autoantibodies associated with juvenile dermatomyositis constitute a distinct phenotype in North America.

Rheumatology (Oxford) 2020 Nov 3. Epub 2020 Nov 3.

Environmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, MD.

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November 2020

Machine learning algorithms reveal unique gene expression profiles in muscle biopsies from patients with different types of myositis.

Ann Rheum Dis 2020 09 16;79(9):1234-1242. Epub 2020 Jun 16.

Muscle Disease Unit, Laboratory of Muscle Stem Cells and Gene Regulation, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Insititutes of Health, Bethesda, Maryland, USA

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September 2020

Increasing Prevalence of Antinuclear Antibodies in the United States.

Arthritis Rheumatol 2020 06 30;72(6):1026-1035. Epub 2020 Apr 30.

National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina.

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June 2020

Population-based estimates of humoral autoimmunity from the U.S. National Health and Nutrition Examination Surveys, 1960-2014.

PLoS One 2020 13;15(1):e0226516. Epub 2020 Jan 13.

National Institute of Environmental Health Sciences, NIH, Bethesda, Maryland, United States of America.

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April 2020

Transethnic associations among immune-mediated diseases and single-nucleotide polymorphisms of the aryl hydrocarbon response gene ARNT and the PTPN22 immune regulatory gene.

J Autoimmun 2020 02 21;107:102363. Epub 2019 Nov 21.

Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health, USA; Research Triangle Park, NC, USA; Bethesda, MD, USA. Electronic address:

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February 2020

Identification of distinctive interferon gene signatures in different types of myositis.

Neurology 2019 09 21;93(12):e1193-e1204. Epub 2019 Aug 21.

From the National Institute of Arthritis and Musculoskeletal and Skin Diseases (I.P.-F, M.C.-D, A.D., K.P., P.P., F.W.M., A.L.M.), NIH, Bethesda; Johns Hopkins University School of Medicine (I.P.-F., M.C.-D., J.P., J.A., L.C.-S., T.E.L., A.M.C., A.L.M.), Baltimore, MD; Clinic Hospital and the University of Barcelona (J.C.M., J.M.G.-J.); Vall d'Hebron Hospital and Autonomous University of Barcelona (A.S.-O.); and Faculty of Health Sciences (I.P.-F.), Universitat Oberta de Catalunya, Barcelona, Spain.

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September 2019

Endothelial Activation Markers as Disease Activity and Damage Measures in Juvenile Dermatomyositis.

J Rheumatol 2020 07 1;47(7):1011-1018. Epub 2019 Aug 1.

From the Environmental Autoimmunity Group, Clinical Research Branch, US National Institute of Environmental Health Sciences, National Institutes of Health (NIH); Coagulation Laboratory, NIH Clinical Center; Laboratories of Molecular Biology and Pathology, National Cancer Institute, NIH, Bethesda, Maryland; Oklahoma Medical Research Foundation; Haus Bioceuticals Inc., Oklahoma City, Oklahoma, USA.

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July 2020

Long-term outcomes in Juvenile Myositis patients.

Semin Arthritis Rheum 2020 02 28;50(1):149-155. Epub 2019 Jun 28.

Division of Rheumatology, Department of Medicine, George Washington University, Washington, DC, United States; Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, MD, United States. Electronic address:

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February 2020

Response to: 'Comment on: 'Anti-Ro52 autoantibodies are associated with interstitial lung disease and more severe disease in patients with juvenile myositis' by Sabbagh S by Yang .

Ann Rheum Dis 2020 08 17;79(8):e97. Epub 2019 Jun 17.

Muscle Disease Unit, Laboratory of Muscle Stem Cells and Gene Expression, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA

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August 2020

Anti-Ro52 autoantibodies are associated with interstitial lung disease and more severe disease in patients with juvenile myositis.

Ann Rheum Dis 2019 07 24;78(7):988-995. Epub 2019 Apr 24.

Environmental Autoimmunity Group, National Institute of EnvironmentalHealth Sciences, National Institutes of Health (NIH), Bethesda, MD, United States.

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July 2019

Prescription medication use and antinuclear antibodies in the United States, 1999-2004.

J Autoimmun 2018 08 18;92:93-103. Epub 2018 May 18.

Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA. Electronic address:

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August 2018

Medications received by patients with juvenile dermatomyositis.

Semin Arthritis Rheum 2018 12 28;48(3):513-522. Epub 2018 Mar 28.

Environmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Building 10, Rm 4-2352, MSC 1301, 10 Center Drive, Bethesda, MD 20892-1301. Electronic address:

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December 2018

Risk factors and disease mechanisms in myositis.

Nat Rev Rheumatol 2018 04;14(5):255-268

Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, Binghamton University, Binghamton, NY, USA.

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April 2018

Anti-NT5C1A autoantibodies are associated with more severe disease in patients with juvenile myositis.

Ann Rheum Dis 2018 05 23;77(5):714-719. Epub 2018 Jan 23.

Muscle Disease Unit, Laboratory of Muscle Stem Cells and Gene Regulation, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health (NIH), Bethesda, Maryland, USA.

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May 2018

Antinuclear antibodies and mortality in the National Health and Nutrition Examination Survey (1999-2004).

PLoS One 2017 9;12(10):e0185977. Epub 2017 Oct 9.

Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland, United States of America.

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October 2017

Environmental factors associated with disease flare in juvenile and adult dermatomyositis.

Rheumatology (Oxford) 2017 08;56(8):1342-1347

Division of Rheumatology, George Washington University School of Medicine and Health Sciences, Washington, DC.

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August 2017

Association of Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Autoantibodies With DRB1*07:01 and Severe Myositis in Juvenile Myositis Patients.

Arthritis Care Res (Hoboken) 2017 07;69(7):1088-1094

Laboratory of Muscle Stem Cells and Gene Expression, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland.

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July 2017

Muscle myeloid type I interferon gene expression may predict therapeutic responses to rituximab in myositis patients.

Rheumatology (Oxford) 2016 09 23;55(9):1673-80. Epub 2016 May 23.

Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, MD, USA

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September 2016

Gene Expression Profiles from Disease Discordant Twins Suggest Shared Antiviral Pathways and Viral Exposures among Multiple Systemic Autoimmune Diseases.

PLoS One 2015 10;10(11):e0142486. Epub 2015 Nov 10.

Environmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland, United States of America.

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June 2016

Magnetic resonance measurement of muscle T2, fat-corrected T2 and fat fraction in the assessment of idiopathic inflammatory myopathies.

Rheumatology (Oxford) 2016 Mar 27;55(3):441-9. Epub 2015 Sep 27.

Environmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences and

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March 2016

Chimeric cells of maternal origin do not appear to be pathogenic in the juvenile idiopathic inflammatory myopathies or muscular dystrophy.

Arthritis Res Ther 2015 Sep 4;17:238. Epub 2015 Sep 4.

National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Environmental Autoimmunity Group, Program of Clinical Research, 9000 Rockville Pike, Bethesda, MD, 20892, USA.

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September 2015

Myositis registries and biorepositories: powerful tools to advance clinical, epidemiologic and pathogenic research.

Curr Opin Rheumatol 2014 Nov;26(6):724-41

aEnvironmental Autoimmunity Group, Program of Clinical Research, National Institute of Environmental Health Sciences, National Institutes of Health (NIH), DHHS, Bethesda, Maryland, USA bDivision of Immunology, 3rd Department of Internal Medicine, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary.

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November 2014

Expert panel workshop consensus statement on the role of the environment in the development of autoimmune disease.

Int J Mol Sci 2014 Aug 15;15(8):14269-97. Epub 2014 Aug 15.

Division of Extramural Research and Training, NIEHS, NIH, Research Triangle Park, NC 27709, USA.

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August 2014

Novel assessment tools to evaluate clinical and laboratory responses in a subset of patients enrolled in the Rituximab in Myositis trial.

Clin Exp Rheumatol 2014 Sep-Oct;32(5):689-96. Epub 2014 Jul 28.

Environmental Autoimmunity Group, Program of Clinical Research, NIEHS, NIH, Department of Health and Human Services (DHHS), Bethesda, MD, USA.

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December 2014

Idiopathic inflammatory myopathies and the anti-synthetase syndrome: a comprehensive review.

Autoimmun Rev 2014 Apr-May;13(4-5):367-71. Epub 2014 Jan 11.

Department of Medicine, University of Calgary, Calgary, Canada. Electronic address:

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May 2014

The myositis autoantibody phenotypes of the juvenile idiopathic inflammatory myopathies.

Medicine (Baltimore) 2013 Jul;92(4):223-243

From Environmental Autoimmunity Group (LGR, MS, GM, FWM), Program of Clinical Research, National Institute of Environmental Health Sciences, National Institutes of Health, DHHS, Bethesda, Maryland; Department of Epidemiology and Biostatistics (MS, MMR) and Division of Rheumatology, Department of Medicine (GM), George Washington University School of Medicine, Washington, DC; Veteran's Affairs Medical Center (INT), University of Oklahoma Health Sciences Center, and Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States; and IWK Health Center and Dalhousie University (AMH), Halifax, Nova Scotia, Canada.

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July 2013

The clinical phenotypes of the juvenile idiopathic inflammatory myopathies.

Medicine (Baltimore) 2013 Jan;92(1):25-41

From the Environmental Autoimmunity Group (MS, GM, FWM, LGR), Program of Clinical Research, National Institute of Environmental Health Sciences; Center for Information Technology (JDM), National Institutes of Health, DHHS, Bethesda, Maryland; Department of Epidemiology and Biostatistics (MS, MMR) and Division of Rheumatology, Department of Medicine(GM), George Washington University School of Medicine, Washington, DC; IWK Health Center and Dalhousie University (AMH), Halifax, Nova Scotia, Canada; and Veteran's Affairs Medical Center (INT), University of Oklahoma Health Sciences Center, and Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma.

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January 2013

Criteria for environmentally associated autoimmune diseases.

J Autoimmun 2012 Dec 6;39(4):253-8. Epub 2012 Jul 6.

Environmental Autoimmunity Group, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health Clinical Research Center, Bethesda, MD 20892-1301, USA.

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December 2012

Epidemiology of environmental exposures and human autoimmune diseases: findings from a National Institute of Environmental Health Sciences Expert Panel Workshop.

J Autoimmun 2012 Dec 25;39(4):259-71. Epub 2012 Jun 25.

Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health Clinical Research Center, Bethesda, MD 20892-1301, USA.

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December 2012

Laboratory Test Abnormalities are Common in Polymyositis and Dermatomyositis and Differ Among Clinical and Demographic Groups.

Open Rheumatol J 2012 1;6:54-63. Epub 2012 Jun 1.

Environmental Autoimmunity Group, Program of Clinical Research, National Institute of Environmental Health Sciences, National Institutes of Health, HHS, Bethesda, Maryland, USA.

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August 2012

Childhood socioeconomic factors and perinatal characteristics influence development of rheumatoid arthritis in adulthood.

Ann Rheum Dis 2013 Mar 14;72(3):350-6. Epub 2012 May 14.

Epidemiology Branch, Division of Intramural Research, National Institute of Environmental Health Sciences, Durham, NC 27599, USA.

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March 2013

New approaches to the assessment and treatment of the idiopathic inflammatory myopathies.

Ann Rheum Dis 2012 Apr;71 Suppl 2:i82-5

Environmental Autoimmunity Group, Program of Clinical Research, National Institute of Environmental Health Sciences, National Institutes of Health Clinical Research Centre, NIH 10, 10 Centre Drive, MSC 1301 Bethesda, MD 20892-1301, USA.

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April 2012

Plasma proteomic profiles from disease-discordant monozygotic twins suggest that molecular pathways are shared in multiple systemic autoimmune diseases.

Arthritis Res Ther 2011 1;13(6):R181. Epub 2011 Nov 1.

Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, DHHS, 9000 Rockville Pike, Bethesda, MD 20892, USA.

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December 2012

Xenotropic murine leukemia virus-related virus is not associated with chronic fatigue syndrome in patients from different areas of the us in the 1990s.

Virol J 2011 Sep 24;8:450. Epub 2011 Sep 24.

Medical Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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September 2011

State of the art: what we know about infectious agents and myositis.

Curr Opin Rheumatol 2011 Nov;23(6):585-94

National Institutes of Health Clinical Research Center, Bethesda, Maryland, USA.

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November 2011

Environmental agents and autoimmune diseases.

Adv Exp Med Biol 2011 ;711:61-81

National Institute of Environmental Health Sciences, National Institutes of Health, HHS, Bethesda, Maryland, USA.

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June 2011

Mass spectrometric determination of IgG subclass-specific glycosylation profiles in siblings discordant for myositis syndromes.

J Proteome Res 2011 Jul 8;10(7):2969-78. Epub 2011 Jun 8.

Laboratory of Structural Biology, NIH/DHHS, Research Triangle Park, North Carolina 27709, USA.

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July 2011

Gene expression profiles from discordant monozygotic twins suggest that molecular pathways are shared among multiple systemic autoimmune diseases.

Arthritis Res Ther 2011 Apr 26;13(2):R69. Epub 2011 Apr 26.

Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA.

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April 2011

Deciphering the clinical presentations, pathogenesis, and treatment of the idiopathic inflammatory myopathies.

JAMA 2011 Jan;305(2):183-90

Environmental Autoimmunity Group, Program of Clinical Research, National Institute of Environmental Health Sciences, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland 20892, USA.

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January 2011

Environmental factors preceding illness onset differ in phenotypes of the juvenile idiopathic inflammatory myopathies.

Rheumatology (Oxford) 2010 Dec 27;49(12):2381-90. Epub 2010 Aug 27.

Environmental Autoimmunity Group, National Institute of Environmental Sciences, National Institutes of Health, DHHS, Clinical Research Center Room 4-2352, 10 Center Drive, MSC 1301, Bethesda, MD 20892-1301, USA.

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December 2010

Microstructure and mineral composition of dystrophic calcification associated with the idiopathic inflammatory myopathies.

Arthritis Res Ther 2009 26;11(5):R159. Epub 2009 Oct 26.

Paffenbarger Research Center, American Dental Association Foundation, National Institute of Standards and Technology, 100 Bureau Drive, Stop 8546, Gaithersburg, MD 20899, USA.

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February 2010

Genetic risk and protective factors for the idiopathic inflammatory myopathies.

Curr Rheumatol Rep 2009 Aug;11(4):287-94

National Institute of Environmental Health Sciences, National Institutes of Health, Room 1W101, Bethesda, MD 20892, USA.

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August 2009

Metabolic abnormalities and cardiovascular risk factors in children with myositis.

J Pediatr 2009 Dec 29;155(6):882-7. Epub 2009 Jul 29.

National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892-1301, USA.

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December 2009

Review of the classification and assessment of the cutaneous manifestations of the idiopathic inflammatory myopathies.

Dermatol Online J 2009 Feb 15;15(2). Epub 2009 Feb 15.

Division of Dermatology, Department of Medicine, Georgetown University Hospital, Washington, DC.

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February 2009

Photoessay of the cutaneous manifestations of the idiopathic inflammatory myopathies.

Dermatol Online J 2009 Feb 15;15(2). Epub 2009 Feb 15.

Division of Dermatology, Department of Medicine, Georgetown University Hospital, Washington, DC.

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February 2009

UV radiation regulates Mi-2 through protein translation and stability.

J Biol Chem 2008 Dec 15;283(50):34976-82. Epub 2008 Oct 15.

Laboratory of Molecular Carcinogenesis, NIEHS, National Intitutes of Health, Research Triangle Park, NC 27709, USA.

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December 2008

Predictors of acquired lipodystrophy in juvenile-onset dermatomyositis and a gradient of severity.

Medicine (Baltimore) 2008 Mar;87(2):70-86

From Office of Clinical Research (AB, GM, LJN, DMC, TPO, PJB, FWM, LGR), National Institute of Environmental Health Sciences; National Institute of Diabetes Digestive and Kidney Diseases (KIR, EO, EC); Department of Radiology (AP) and Nutrition Department (NS), Clinical Center; National Cancer Institute (DK, MT); National Institutes of Health (NIH), Bethesda, Maryland; Penn State Milton S. Hershey Medical Center (AB), Hershey, Pennsylvania; University of Michigan (EO), Ann Arbor, Michigan; Veterans Affairs Medical Center, University of Oklahoma Health Sciences Center, and Oklahoma Medical Research Foundation (INT), Oklahoma City, Oklahoma; Medical University of South Carolina (JPP), Charleston, South Carolina; Center for Biologics Evaluation and Research (MRH, JL, SRB), Food and Drug Administration, Bethesda, Maryland; Warren Alpert Medical School of Brown University (LBG), Providence, Rhode Island; Columbia University (LI), New York, New York, United States; and Facultad de Medicina/CRIB (MRH, JL), Universidad de Castilla-La Mancha, Albacete, Spain.

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March 2008